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This thesis is an investigation of Middle English insanity language. It analyses change in the Middle English lexical field of INSANITY, the semantic structure of lexemes wod and mad, and compares INSANITY conceptual metaphors in Middle English and present-day English. The INSANITY lexical field is an ideal one to study language change, due to socio-cultural changes since the Middle Ages such as advances in medical knowledge, the development of the field of psychiatry and legal changes protecting people with a mental illness from discrimination. The general theoretical aims were to examine a) change in conceptual metaphor, and b) semantic and lexical change with a particular focus on the decline in use of adjective wod. The theoretical frameworks are cognitive linguistics, prototype theory, and conceptual metaphor theory, and the data is derived from Middle English corpora and other sources. The INSANITY database I created for this study consisted of 1307 instances of mad, wod and near-synonyms in context. The main results can be divided into three groups. Firstly, the lexical field study demonstrates that various intra-linguistic and socio-cultural phenomena effect lexical change. Using case studies amongst others of the decline of wod in the Wycliffite Bible and of Caxton's translations from French, and a systematic variation across genre, I argue that the important factors are i) the arrival of new medical loanwords such as frensy, lunatic and malencolie; ii) the early re-emergence of the vernacular in medical texts starting in the twelfth century, and the development of a new medical register; iii) the so-called medieval 'inward turn'; iv) changes in the neighbouring lexical field of ANGER. Secondly, the semasiological study of wod and mad shows that the meanings of these two lexemes are structured and change in line with the central tenets of prototype theory, i.e. as described for diachronic prototype semantics by Geeraerts (1997). The path of mad's semantic development does not parallel that of wod after the thirteenth century. Mad's senses do not have the emphasis on wildness and fury that the senses of wod do. A particularly interesting finding is the semantic change from a sub-sense of adverb mad and adjective mad, 'unrestrained', leading in present-day English to a new delexicalised and grammaticalised sense of mad, where its use as an intensifier enhances scalar quantity and quality. Thirdly, the conceptual metaphor study demonstrates that predominantly the same conceptual metaphors are seen in both Middle English and present-day English, with some exceptions such as the concept of insanity being related to moral decline, as evidenced in the dearth of FALLING metaphors for insanity in present-day English. Conceptual metaphors such as INSANITY IS ANOTHER PLACE are evidenced in present-day English expressions such as out of her senses, or not in my right mind. In 1422, Thomas Hoccleve could write of a dysseveraunce between himself and his wit, or about his wyld infirmitie, which threw him owt of my selfe, illustrating the same underlying concepts. Other INSANITY conceptual metaphors which remain unchanged are GOING ASTRAY, LACK OF ORDER, LACK OF WHOLENESS, DARKNESS, FORCE, PRISON and BURDEN. Because of its unique approach in combining onomasiological and semasiological approaches with a conceptual metaphor study, this study reveals not only specific patterns of change, but differences in the rate of change on the lexical and conceptual levels. Lexical change driven by the need to be expressive, and reflecting socio-cultural changes such as changes in medical knowledge, can be seen to happen rapidly over the Middle English period. However, underlying conceptual change is barely discernible even over a much longer period of time from Middle English to present-day English. This research is significant because it provides a basis for future analysis of insanity language in other periods and contexts. It also contributes to the study of semantic change in general, highlighting the insights that can be gained by combining different types of data-driven analyses.

Pediatric brain cancer is a rare and potentially deadly diagnosis that affects children in Kentucky at a higher incidence than those nationally. Limited exposures in children early in life to warrant the development and progression of brain cancer point to the role parental exposures experienced in the period prior to conception and throughout pregnancy may play in its development. Many of these exposures may be experienced through occupation. Data on a subset of pediatric brain cancer cases in Kentucky was compared to all cases diagnosed in the state from 1995 to 2019. Survey data of the study sample was collected and work-related characteristics of biological mothers of the sample were standardized using industry codes and analyzed to identify occupation fields with potential associations to pediatric brain cancer. Cases diagnosed at a younger age and those from metropolitan areas were over-represented in the sample. The maternal occupation of the sample varied slightly from the occupational prevalence of the general population. However, since the comparison was made to all working women in the United States 16 years and older, the comparison is flawed. Additional research is needed to verify these findings and identify additional exposures that may contribute to cancer development.

This qualitative study used focus groups to explore and understand the experiences of 13 self-identified Latina students who were attending a predominantly White university in the Midwest. The use of Chicana feminist theory and academic and social integration theory helped frame the study. Similarities and differences among Latinas, as well as an exploration of the intersections of gender, race, ethnicity, and culture in relation to the experiences of Latinas while attending college at a predominantly White university in the Midwest were highlighted. Through the exploration of their lived experiences, participants identified the factors and conditions affecting their experiences in college, how family and culture shaped their experiences, and how their perceptions of the campus environment shaped their experiences while in college. The results of this study suggest that maintaining close ties to family members, having a space on campus to practice and enjoy Latino culture, being resilient, and finding their niche in the campus environment through programs focused on underrepresented students were the keys to their persistence in college. Another major finding of this study, that requires further study, is the undesirable change in the relationship between Latina mothers and daughters as the daughter furthers her education. Many participants’ close relationships with their mothers were instrumental to their enrolling in college yet tension arose between mother and daughter as the daughter progressed toward graduation.