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Presents several letters to the editor. Testimony made before the U.S. Senate Committee regarding removal of postmasters upon secret charges; Legalization of mortgage contracts; Trade association formed by manufacturers and dealers in dental supplies.

Presents letters to the editor. Requirement and supply of teachers in the U.S. Schools; Book on the history of Medford by Charles Brooks.

Presents several letters to the editor. Comments on the silver question; Discussion about the Inter-State Commerce Bill; Schemes for aiding the poor by legislation.

Replication factor C (RFC) is an essential, multi-subunit ATPase that functions in DNA replication, DNA repair, and DNA metabolism-related checkpoints. In order to investigate how the individual RFC subunits contribute to these functions in vivo, we undertook a genetic analysis ofRFCgenes from budding yeast. We isolated and characterized mutations in theRFC5gene that could suppress the cold-sensitive phenotype ofrfc1-1mutants. Analysis of theRFC5suppressors revealed that they could not suppress the elongated telomere phenotype, the sensitivity to DNA damaging agents, or the mutator phenotype ofrfc1-1mutants. Unlike the checkpoint-defectiverfc5-1mutation, theRFC5suppressor mutations did not interfere with the methylmethane sulfonate- or hydroxyurea-induced phosphorylation of Rad53p. The Rfc5p suppressor substitutions mapped to amino acid positions in the conserved RFC box motifs IV–VII. Comparisons of the structures of related RFC box-containing proteins suggest that these RFC motifs may function to coordinate interactions between neighboring subunits of multi-subunit ATPases.

One of the textile industry’s largest consumers of energy is the tenter frame dryer. To assist the industry in operating these dryers efficiently, a mathematical model which simulates the drying process and a scheme to solve for the parameters in the differential equations of the model have been developed and are presented in this paper. Temperature profiles predicted from the model are compared with profiles measured on commercial dryers. Also dryer simulation studies to elucidate optimal operating conditions are discussed.

Five-thousand foot isobars are argued for again for the plateau area. The argument brings in typical examples which show comparatively the value of one system against the standard procedure.

Presents letters to the editor. Retention of William T. Harris as commissioner of education; Discussion on the anti-foreign spirit in Japan; Comments on the tariff on books.