201 results on '"Beck WC"'
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2. AIDS: Is It an Ill Wind?
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Beck, WC. and Meyer, Kenneth
- Abstract
Historically, infection control can, we believe, be divided into three eras, each lasting about a half century. We wonder whether we are now seeing the beginning of a fourth.The first era, which we call the nascent period, began roughly in the middle of the last century. It arose from the discoveries of Ignaz Semmelweis and Florence Nightingale. The benefits of each of their contributions on hospital mortality were so spectacular that they would qualify for the “lead ball” award. (Del Gurchio quoted Lloyd MacLean as saying, “If you hold a lead ball out of the window and when you let it go it goes up, you do not need a statistician to tell you it was a significant event.” Hence, the “lead ball” award.)The second era would be the aseptic period. It dates from the acceptance of the findings of Pasteur, Lister, and Koch. Their concepts achieved general acceptance, after a hard fight, at the beginning of the 20th century.
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- 1992
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3. CDC field triage criteria accurately predicts outcomes in high impact trauma.
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Sifford MC, Dailey R, Reif R, Hutchison M, Mason C, Kimbrough K, Davis B, Bhavaraju A, Jensen HK, Robertson R, Taylor J, Beck WC, and Sexton K
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- Centers for Disease Control and Prevention, U.S., Humans, Injury Severity Score, Retrospective Studies, Trauma Centers, United States, Triage methods, Wounds and Injuries therapy
- Abstract
Background: The precision of emergency medical services (EMS) triage criteria dictates whether an injured patient receives appropriate care. The trauma triage protocol is a decision scheme that groups patients into triage categories of major, moderate and minor. We hypothesized that there is a difference between trauma triage category and injury severity score (ISS)., Methods: This retrospective, observational study was conducted to investigate a difference between trauma triage category and ISS. Bivariate analysis was used to test for differences between the subgroup means. The differences between the group means on each measure were analyzed for direction and statistical significance using ANOVA for continuous variables and chi square tests for categorical variables. Logistic and linear regressions were performed to evaluate factors predicting mortality, ICU length of stay., Results: With respect to trauma triage category, our findings indicate that minor and moderate triage categories are similar with respect to ISS, GCS, ICU LOS, hospital LOS, and mortality. However, after excluding for low impact injuries (falls), differences between the minor and moderate categories were evident when comparing to ISS, GCS, ICU LOS, and hospital LOS. Additionally, after excluding for low impact injures, ISS, ICU LOS, and hospital stay were found to correlate well with trauma triage category., Conclusions: In this retrospective, observational study significant differences were not seen when comparing ISS with the trauma triage categories of moderate and minor during our initial analysis. However, a difference was found after excluding for low impact injuries. These findings suggest that CDC criteria accurately predicts outcomes in high impact trauma.
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- 2022
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4. Avoiding Cribari gridlock 2: The standardized triage assessment tool outperforms the Cribari matrix method in 38 adult and pediatric trauma centers.
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Roden-Foreman JW, Rapier NR, Foreman ML, Cribari C, Parsons M, Zagel AL, Cull J, Coniglio RA, McGraw C, Blackmore AR, Lyell CA, Adams CA Jr, Lueckel SN, Regner JL, Holzmacher J, Sarani B, Sexton KW, Beck WC, Milia DJ, Hess JC, Workman CF, Greenwell C, Weaver M, Agrawal V, Amos JD, Nance ML, Campbell M, Dunn J, Steen S, McGonigal MD, Schroeppel TJ, Putty B, Sherar D, and Flohr SD
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- Adult, Child, Humans, Injury Severity Score, Patient Discharge, Retrospective Studies, Triage, Workload, Trauma Centers, Wounds and Injuries
- Abstract
Objectives: The Cribari Matrix Method (CMM) is the current standard to identify over/undertriage but requires manual trauma triage reviews to address its inadequacies. The Standardized Triage Assessment Tool (STAT) partially emulates triage review by combining CMM with the Need For Trauma Intervention, an indicator of major trauma. This study aimed to validate STAT in a multicenter sample., Methods: Thirty-eight adult and pediatric US trauma centers submitted data for 97,282 encounters. Mixed models estimated the effects of overtriage and undertriage versus appropriate triage on the odds of complication, odds of discharge to a continuing care facility, and differences in length of stay for both CMM and STAT. Significance was assessed at p <0.005., Results: Overtriage (53.49% vs. 30.79%) and undertriage (17.19% vs. 3.55%) rates were notably lower with STAT than with CMM. CMM and STAT had significant associations with all outcomes, with overtriages demonstrating lower injury burdens and undertriages showing higher injury burdens than appropriately triaged patients. STAT indicated significantly stronger associations with outcomes than CMM, except in odds of discharge to continuing care facility among patients who received a full trauma team activation where STAT and CMM were similar., Conclusions: This multicenter study strongly indicates STAT safely and accurately flags fewer cases for triage reviews, thereby reducing the subjectivity introduced by manual triage determinations. This may enable better refinement of activation criteria and reduced workload., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Author KWS declares that he is funded by the University of Arkansas for Medical Sciences Clinician Scientist Program. All other authors report no conflicts of interest or competing interests exist., (Copyright © 2020. Published by Elsevier Ltd.)
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- 2021
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5. Hemorrhage-Control Training in Medical Education.
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Gowen JT, Sexton KW, Thrush C, Privratsky A, Beck WC, Taylor JR, Davis B, Kimbrough MK, Jensen HK, Robertson RD, and Bhavaraju A
- Abstract
Objectives: To evaluate and analyze the efficacy of implementation of hemorrhage-control training into the formal medical school curriculum. We predict this training will increase the comfort and confidence levels of students with controlling major hemorrhage and they will find this a valuable skill set for medical and other healthcare professional students., Methods: After IRB and institutional approval was obtained, hemorrhage-control education was incorporated into the surgery clerkship curriculum for 96 third-year medical students at the University of Arkansas for Medical Sciences using the national Stop The Bleed program. Using a prospective study design, participants completed pre- and post-training surveys to gauge prior experiences and comfort levels with controlling hemorrhage and confidence levels with the techniques taught. Course participation was mandatory; survey completion was optional. The investigators were blinded as to the individual student's survey responses. A knowledge quiz was completed following the training., Results: Implementation of STB training resulted in a significant increase in comfort and confidence among students with all hemorrhage-control techniques. There was also a significant difference in students' perceptions of the importance of this training for physicians and other allied health professionals., Conclusion: Hemorrhage-control training can be effectively incorporated into the formal medical school curriculum via a single 2-hour Stop The Bleed course, increasing students' comfort level and confidence with controlling major traumatic bleeding. Students value this training and feel it is a beneficial addition to their education. We believe this should be a standard part of undergraduate medical education., Competing Interests: Declaration of conflicting Interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2020.)
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- 2020
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6. Characterization of Acidosis in Trauma Patient.
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Corwin GS, Sexton KW, Beck WC, Taylor JR, Bhavaraju A, Davis B, Kimbrough MK, Jensen JC, Privratsky A, and Robertson RD
- Abstract
Background: Recent data suggest that acidosis alone is not a good predictor of mortality in trauma patients. Little data are currently available regarding factors associated with survival in trauma patients presenting with acidosis., Aims: The aims were to characterize the outcomes of trauma patients presenting with acidosis and to identify modifiable risk factors associated with mortality in these patients., Settings and Design: This is a retrospective observational study of University of Arkansas for Medical Sciences (UAMS) trauma patients between November 23, 2013, and May 21, 2017., Methods: Data were collected from the UAMS trauma registry. The primary outcome was hospital mortality. Analyses were performed using t-test and Pearson's Chi-squared test. Simple and multiple logistic regressions were performed to determine crude and adjusted odds ratios., Results: There were 532 patients identified and 64.7% were acidotic (pH < 7.35) on presentation: 75.9% pH 7.2-7.35; 18.5% pH 7.0-7.2; and 5.6% pH ≤ 7.0. The total hospital mortality was 23.7%. Nonsurvivors were older and more acidotic, with a base deficit >-8, Glasgow Coma Scale (GCS) ≤ 8, systolic blood pressure ≤ 90, International Normalized Ratio (INR) >1.6, and Injury Severity Score (ISS) >15. Mortality was significantly higher with a pH ≤ 7.2 but mortality with a pH 7.2-7.35 was comparable to pH > 7.35. In the adjusted model, pH ≤ 7.0, pH 7.0-7.2, INR > 1.6, GCS ≤ 8, and ISS > 15 were associated with increased mortality. For patients with a pH ≤ 7.2, only INR was associated with increase in mortality., Conclusions: A pH ≤ 7.2 is associated with increased mortality. For patients in this range, only the presence of coagulopathy is associated with increased mortality. A pH > 7.2 may be an appropriate treatment goal for acidosis. Further work is needed to identify and target potentially modifiable factors in patients with acidosis such as coagulopathy., Competing Interests: There are no conflicts of interest., (Copyright: © 2020 Journal of Emergencies, Trauma, and Shock.)
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- 2020
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7. ROTEM as a Predictor of Mortality in Patients With Severe Trauma.
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Smith AR, Karim SA, Reif RR, Beck WC, Taylor JR, Davis BL, Bhavaraju AV, Jensen HK, Kimbrough MK, and Sexton KW
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- Adult, Aged, Arkansas epidemiology, Female, Humans, Male, Middle Aged, Retrospective Studies, Trauma Centers statistics & numerical data, Trauma Severity Indices, Thrombelastography, Wounds and Injuries mortality
- Abstract
Background: Hemorrhage, especially when complicated by coagulopathy, is the most preventable cause of death in trauma patients. We hypothesized that assessing hemostatic function using rotational thromboelastometry (ROTEM) or conventional coagulation tests can predict the risk of mortality in patients with severe trauma indicated by an injury severity score greater than 15., Methods: We retrospectively reviewed trauma patients with an injury severity score >15 who were admitted to the emergency department between November 2015 and August 2017 in a single level I trauma center. Patients with available ROTEM and conventional coagulation data (partial thromboplastin time [PTT], prothrombin time [PT], and international normalized ratio) were included in the study cohort. Logistic regression was performed to assess the relationship between coagulation status and mortality., Results: The study cohort included 301 patients with an average age of 47 y, and 75% of the patients were males. Mortality was 23% (n = 68). Significant predictors of mortality included abnormal APTEM (thromboelastometry (TEM) assay in which fibrinolysis is inhibited by aprotinin (AP) in the reagent) parameters, specifically a low APTEM alpha angle, a high APTEM clot formation time, and a high APTEM clotting time. In addition, an abnormal international normalized ratio significantly predicted mortality, whereas abnormal PT and PTT did not., Conclusions: A low APTEM alpha angle, an elevated APTEM clot formation time, and a high APTEM clotting time significantly predicted mortality, whereas abnormal PT and PTT did not appear to be associated with increased mortality in this patient population. Viscoelastic testing such as ROTEM appears to have indications in the management and stabilization of trauma patients., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2020
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8. Rethinking the definition of major trauma: The need for trauma intervention outperforms Injury Severity Score and Revised Trauma Score in 38 adult and pediatric trauma centers.
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Roden-Foreman JW, Rapier NR, Foreman ML, Zagel AL, Sexton KW, Beck WC, McGraw C, Coniglio RA, Blackmore AR, Holzmacher J, Sarani B, Hess JC, Greenwell C, Adams CA Jr, Lueckel SN, Weaver M, Agrawal V, Amos JD, Workman CF, Milia DJ, Bertelson A, Dorlac W, Warne MJ, Cull J, Lyell CA, Regner JL, McGonigal MD, Flohr SD, Steen S, Nance ML, Campbell M, Putty B, Sherar D, and Schroeppel TJ
- Subjects
- Adolescent, Adult, Age Factors, Aged, Female, Humans, Male, Middle Aged, Prognosis, Trauma Centers statistics & numerical data, United States, Wounds and Injuries diagnosis, Wounds and Injuries pathology, Wounds and Injuries therapy, Young Adult, Injury Severity Score, Trauma Severity Indices, Wounds and Injuries classification
- Abstract
Background: Patients' trauma burdens are a combination of anatomic damage, physiologic derangement, and the resultant depletion of reserve. Typically, Injury Severity Score (ISS) >15 defines major anatomic injury and Revised Trauma Score (RTS) <7.84 defines major physiologic derangement, but there is no standard definition for reserve. The Need For Trauma Intervention (NFTI) identifies severely depleted reserves (NFTI+) with emergent interventions and/or early mortality. We hypothesized NFTI would have stronger associations with outcomes and better model fit than ISS and RTS., Methods: Thirty-eight adult and pediatric U.S. trauma centers submitted data for 88,488 encounters. Mixed models tested ISS greater than 15, RTS less than 7.84, and NFTI's associations with complications, survivors' discharge to continuing care, and survivors' length of stay (LOS)., Results: The NFTI had stronger associations with complications and LOS than ISS and RTS (odds ratios [99.5% confidence interval]: NFTI = 9.44 [8.46-10.53]; ISS = 5.94 [5.36-6.60], RTS = 4.79 [4.29-5.34]; LOS incidence rate ratios (99.5% confidence interval): NFTI = 3.15 [3.08-3.22], ISS = 2.87 [2.80-2.94], RTS = 2.37 [2.30-2.45]). NFTI was more strongly associated with continuing care discharge but not significantly more than ISS (relative risk [99.5% confidence interval]: NFTI = 2.59 [2.52-2.66], ISS = 2.51 [2.44-2.59], RTS = 2.37 [2.28-2.46]). Cross-validation revealed that in all cases NFTI's model provided a much better fit than ISS greater than 15 or RTS less than 7.84., Conclusion: In this multicenter study, NFTI had better model fit and stronger associations with the outcomes than ISS and RTS. By determining depletion of reserve via resource consumption, NFTI+ may be a better definition of major trauma than the standard definitions of ISS greater than 15 and RTS less than 7.84. Using NFTI may improve retrospective triage monitoring and statistical risk adjustments., Level of Evidence: Prognostic, level IV.
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- 2019
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9. Is It Safe to Fly Patients with Penetrating Trauma in a Rural State?
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Greer JW, Reif R, Karim S, Beck WC, Bhavaraju A, Davis B, Taylor JR, and Sexton KW
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- Adolescent, Adult, Female, Humans, Injury Severity Score, Logistic Models, Male, Middle Aged, Retrospective Studies, Rural Population, Trauma Centers, Wounds, Penetrating mortality, Young Adult, Air Ambulances, Wounds, Penetrating therapy
- Abstract
Background: There is limited data pertaining to the triage and transportation of patients with penetrating trauma in rural states. Large urban trauma centers have found rapid transport to be beneficial even when done by nonemergency medical staff. However, there is limited application to a rural state with only a single level 1 trauma center., Materials and Methods: This a retrospective observational study of 854 trauma patients transported by helicopter emergency services between 2009 and 2015 to the state's only level 1 trauma center., Results: After excluding patients with other injuries or lack of data, 854 patients underwent final analysis. Compared with penetrating trauma, blunt trauma had a significantly different chance of survival (92.0% versus 81.2%, P = 0.002) and a significantly different injury severity score (17 ± 12 versus 12 ± 9, P = 0.002). After controlling for blunt injuries, age, gender, injury severity score, tachycardia, tachypnea, hypotension, glasgow coma scale, and dispatch to hospital arrival time in multivariate analysis, blunt trauma had higher odds of survival than penetrating trauma (OR, 5.97; 95% CI, 2.52-14.12; P = <0.001 = 1). Gender, tachycardia, tachypnea, and dispatch to arrival time did not impact a patient's likelihood of survival., Conclusions: Penetrating trauma has a higher mortality when compared with blunt trauma in Helicopter Emergency Services transported patients in a rural state. Perhaps a new algorithm in the management of penetrating trauma would include hemorrhage control at a locoregional hospital before definitive care. Further study is required to understand the exact variables that lead to a higher mortality in penetrating trauma in a rural state., (Published by Elsevier Inc.)
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- 2019
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10. Right external iliac artery thrombus following the use of resuscitative endovascular balloon occlusion of the aorta for placenta accreta.
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Greer JW, Flanagan C, Bhavaraju A, Davis B, Kimbrough MK, Privratsky A, Robertson R, Taylor JR, Sexton KW, and Beck WC
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A 33-year-old female, 32 weeks and 1 day gestation, with known placenta accreta who presented to the emergency department with 2 h of severe abdominal pain, nausea and vomiting. She became hypotensive and underwent emergency cesarean section. Emergency general surgery was consulted for placement of a resuscitative endovascular balloon for aortic occlusion (REBOA). After successful delivery, the balloon was inflated in zone 3 and systolic blood pressure rose from 70 to 170 mmHg. The patient underwent hysterectomy for ongoing hemorrhage. The patient was taken to the surgical intensive care unit. The patient was noted to have pulses following removal of the sheath. Arterial brachial indices and arterial duplex was performed 48 h after sheath removal. The patient was found to have complete occlusion of the right external iliac artery. Vascular surgery was consulted and cut-down performed with thrombus removal via fogarty catheter. The patient was discharged 2 days later without further complication.
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- 2018
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11. Morning report decreases length of stay in trauma patients.
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Wolfe JD, Gardner JR, Beck WC, Taylor JR, Bhavaraju A, Davis B, Kimbrough MK, Robertson RD, Karim SA, and Sexton KW
- Abstract
Background: Modern acute care surgery (ACS) programs depend on consistent patient hand-offs to facilitate care, as most programs have transitioned to shift-based coverage. We sought to determine the impact of implementing a morning report (MR) model on patient outcomes in the trauma service of a tertiary care center., Methods: The University of Arkansas for Medical Sciences (UAMS) Division of ACS implemented MR in October 2015, which consists of the trauma day team, the emergency general surgery day team, and a combined night float team. This study queried the UAMS Trauma Registry and the Arkansas Clinical Data Repository for all patients meeting the National Trauma Data Bank inclusion criteria from January 1, 2011 to April 30, 2018. Bivariate frequency statistics and generalized linear model were run using STATA V.14.2., Results: A total of 11 253 patients (pre-MR, n=6556; post-MR, n=4697) were analyzed in this study. The generalized linear model indicates that implementation of MR resulted in a significant decrease in length of stay (LOS) in trauma patients., Discussion: This study describes an approach to improving patient outcomes in a trauma surgery service of a tertiary care center. The data show how an MR session can allow for patients to get out of the hospital faster; however, broader implications of these sessions have yet to be studied. Further work is needed to describe the decisions being made that allow for a decreased LOS, what dynamics exist between the attendings and the residents in these sessions, and if these sessions can show some of the same benefits in other surgical services., Level of Evidence: Level 4, Care Management., Competing Interests: Competing interests: None declared.
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- 2018
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12. Dilated cardiomyopathy secondary to acute pancreatitis caused by hypertriglyceridemia.
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Greer JW, Beck WC, Bhavaraju A, Davis B, Kimbrough MK, Jensen J, Privratsky A, Robertson R, Taylor JR, and Sexton KW
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A 30-year-old male presented to an outside facility with acute pancreatitis and triglycerides of 1594. He was transferred to our facility after becoming febrile, hypoxic and in acute renal failure with triglycerides of 4243. CT scan performed showed wall-off pancreatic necrosis. He underwent continuous renal replacement therapy and his acute renal failure resolved. He was treated with broad spectrum antibiotics and discharged. He developed a fever to 101 a week later and was found to have a large infected pancreatic pseudocyst. This was managed with an IR placed drain. This was continued for 6 weeks. He came to the emergency department several weeks later with shortness of breath and 3+ edema to bilateral lower extremities and lower abdomen. TTE performed showed an EF of 15%. He was diuresed 25 L during that stay. His heart failure was medically managed. We present this case of dilated cardiomyopathy secondary to acute pancreatitis.
- Published
- 2018
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13. Severe acute gallstone pancreatitis with diffuse hemorrhagic gastritis.
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Harris TJ, Beck WC, Bhavaraju A, Davis B, Kimbrough MK, Jensen JC, Privratsky A, Taylor JR, and Sexton KW
- Abstract
A 67-year-old male presented with acute pancreatitis secondary to gallstones, also known as acute biliary pancreatitis, and subsequently developed gastric outlet obstruction and was transferred to our hospital. A gastro-jejunal feeding tube was placed and an open cholecystectomy was performed. The patient had a pancreatic drain placed for interval increase in pancreatic necrosis and then nearly exsanguinated from gastroduodenal artery pseudoaneurysm bleed. This was managed by coiling the gastroduodenal artery. The patient underwent a pancreatic necrosectomy with malencot drain placement and developed a post-operative upper gastrointestinal bleeding. An EGD showed diffuse gastritis, but no varices. And 18 days later the patient rebled, with the same diffuse gastritis. After further complications the patient elected to receive palliative care at a hospice facility. We are presenting this unusual case of diffuse, hemorrhagic gastritis after acute necrotizing pancreatitis.
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- 2018
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14. Identifying Barriers to Microlaparoscopy in the Performance of Surgical Procedures.
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LeCompte MT, Baucom RB, Beck WC, Holzman MD, Sharp KW, Nealon WH, and Poulose BK
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- Body Mass Index, Female, Humans, Laparoscopy instrumentation, Laparoscopy statistics & numerical data, Male, Microsurgery instrumentation, Microsurgery statistics & numerical data, Middle Aged, Operative Time, Prospective Studies, Surgical Instruments, Laparoscopy methods, Microsurgery methods
- Published
- 2017
15. The importance of surgeon-reviewed computed tomography for incisional hernia detection: a prospective study.
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Baucom RB, Beck WC, Holzman MD, Sharp KW, Nealon WH, and Poulose BK
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- Adult, Aged, Female, General Surgery, Hernia, Ventral etiology, Humans, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Referral and Consultation, Sensitivity and Specificity, Single-Blind Method, Hernia, Ventral diagnostic imaging, Postoperative Complications diagnostic imaging, Tomography, X-Ray Computed
- Abstract
Patients with incisional hernias or abdominal pain are frequently referred with abdominal computed tomography (CT) scans. The purpose of this study was to determine the sensitivity and specificity of a CT radiology report for the detection of incisional hernias. General surgery patients with a history of an abdominal operation and a recent viewable abdominal CT scan were enrolled prospectively. Patients with a stoma, fistula, or soft tissue infection were excluded. The results of the radiology reports were compared with blinded, surgeon-interpreted CT for each patient. Testing characteristics including sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. One hundred eighty-one patients were enrolled with a mean age of 54 years. Sixty-eight per cent were women. Hernia prevalence was 55 per cent, and mean hernia width was 5.2 cm. The radiology report had a sensitivity and specificity of 79 per cent and 94 per cent, respectively, for hernia diagnosis. The PPV and NPV were 94 and 79 per cent, respectively. Reliance on the CT report alone underestimates the presence of incisional hernia. Referring physicians should not use CT as a screening modality for detection of hernias. Referral to a surgeon for evaluation before imaging may provide more accurate diagnosis and potentially decrease the cost of caring for this population.
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- 2014
16. Comparative Evaluation of Dynamic Abdominal Sonography for Hernia and Computed Tomography for Characterization of Incisional Hernia.
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Baucom RB, Beck WC, Phillips SE, Holzman MD, Sharp KW, Nealon WH, and Poulose BK
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- Comparative Effectiveness Research, Female, Humans, Male, Middle Aged, Prospective Studies, Sensitivity and Specificity, Hernia, Ventral diagnostic imaging, Tomography, X-Ray Computed, Ultrasonography methods
- Abstract
Importance: Previous work has demonstrated that dynamic abdominal sonography for hernia (DASH) is accurate for the diagnosis of incisional hernia. The usefulness of DASH for characterization of incisional hernia is unknown., Objective: To determine whether DASH can be objectively used to characterize incisional hernias by measurement of mean surface area (MSA)., Design, Setting, and Participants: A prospective cohort study was conducted. A total of 109 adults with incisional hernia were enrolled between July 1, 2010, and March 1, 2012. Patients with a stoma, fistula, or soft-tissue infection were excluded., Interventions: DASH was performed by a surgeon to determine the maximal transverse and craniocaudal dimensions of the incisional hernia. A separate surgeon, blinded to the DASH results, performed the same measurements using computed tomography (CT)., Main Outcomes and Measures: The MSA was calculated, and the difference in MSA by DASH and CT was compared using the Wilcoxon signed rank test. Subset analysis was performed with patients stratified into nonobese, obese, and morbidly obese groups. We hypothesized that there was no significant difference between MSA as measured by DASH compared with CT., Results: A total of 109 patients were enrolled (mean age, 56 years; mean body mass index, 32.2 [calculated as weight in kilograms divided by height in meters squared]; and 67.0% women). The mean (SD) MSA measurements were similar between the modalities: DASH, 41.8 (67.5) cm2 and CT, 44.6 (78.4) cm2 (P = .82). The MSA measurements determined by DASH and CT were also similar for all groups when stratified by body mass index. There were 15 patients who had a hernia 10 cm or larger in transverse dimension. The mean body mass index of this group was 39.2, and the MSA measurements by DASH and CT were similar (P = .26)., Conclusions and Relevance: DASH can be used to objectively characterize hernias by MSA, with accuracy demonstrated in the obese population and in patients whose hernias were very large (≥10 cm in diameter). DASH offers the advantages of real-time imaging and no ionizing radiation and may obviate the need for the patient to schedule additional imaging appointments.
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- 2014
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17. Prospective evaluation of surgeon physical examination for detection of incisional hernias.
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Baucom RB, Beck WC, Holzman MD, Sharp KW, Nealon WH, and Poulose BK
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- Female, Hernia, Abdominal diagnostic imaging, Humans, Laparoscopy, Male, Middle Aged, Predictive Value of Tests, Prospective Studies, Recurrence, Sensitivity and Specificity, Tomography, X-Ray Computed, Diagnostic Errors statistics & numerical data, Hernia, Abdominal diagnosis, Hernia, Abdominal surgery, Physical Examination
- Abstract
Background: Surgeon physical examination is often used to monitor for hernia recurrence in clinical and research settings, despite a lack of information on its effectiveness. This study aims to compare surgeon-reviewed CT with surgeon physical examination for the detection of incisional hernia., Study Design: General surgery patients with an earlier abdominal operation and a recent viewable CT scan of the abdomen and pelvis were enrolled prospectively. Patients with a stoma, fistula, or soft-tissue infection were excluded. Surgeon-reviewed CT was treated as the gold standard. Patients were stratified by body mass index into nonobese (body mass index <30) and obese groups. Testing characteristics and real-world performance, including positive predictive value and negative predictive value, were calculated., Results: One hundred and eighty-one patients (mean age 54 years, 68% female) were enrolled. Hernia prevalence was 55%. Mean area of hernias was 44.6 cm(2). Surgeon physical examination had a low sensitivity (77%) and negative predictive value (77%). This difference was more pronounced in obese patients, with sensitivity of 73% and negative predictive value 69%., Conclusions: Surgeon physical examination is inferior to CT for detection of incisional hernia, and fails to detect approximately 23% of hernias. In obese patients, 31% of hernias are missed by surgeon physical examination. This has important implications for clinical follow-up and design of studies evaluating hernia recurrence, as ascertainment of this result must be reliable and accurate., (Copyright © 2014 American College of Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2014
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18. Disease-based mortality after percutaneous endoscopic gastrostomy: utility of the enterprise data warehouse.
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Poulose BK, Kaiser J, Beck WC, Jackson P, Nealon WH, Sharp KW, and Holzman MD
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- Comorbidity, Diabetes Mellitus mortality, Enteral Nutrition statistics & numerical data, Female, Follow-Up Studies, Gastrostomy adverse effects, Gastrostomy methods, Heart Failure mortality, Humans, Male, Middle Aged, Neoplasms mortality, Pulmonary Disease, Chronic Obstructive mortality, Risk Factors, Stroke mortality, Survival Analysis, Survival Rate, Gastrostomy mortality
- Abstract
Background: Percutaneous endoscopic gastrostomy (PEG) remains a mainstay of enteral access. Thirty-day mortality for PEG has ranged from 16 to 43 %. This study aims to discern patient groups that demonstrate limited survival after PEG placement. The Enterprise Data Warehouse (EDW) concept allows an efficient means of integrating administrative, clinical, and quality-of-life data. On the basis of this concept, we developed the Vanderbilt Procedural Outcomes Database (VPOD) and analyzed these data for evaluation of post-PEG mortality over time., Methods: Patients were identified using the VPOD from 2008 to 2010 and followed for 1 year after the procedure. Patients were categorized according to common clinical groups for PEG placement: stroke/CNS tumors, neuromuscular disorders, head and neck cancers, other malignancies, trauma, cerebral palsy, gastroparesis, or other indications for PEG. All-cause mortality at 30, 60, 90, 180, and 360 days was determined by linking VPOD information with the Social Security Death Index. Chi-square analysis was used to determine significance across groups., Results: Nine hundred fifty-three patients underwent PEG placement during the study period. Mortality over time (30-, 60-, 90-, 180-, and 360-day mortality) was greatest for patients with malignancies other than head and neck cancer (29, 45, 57, 66, and 72 %) and least for cerebral palsy or patients with gastroparesis (7 % at all time points). Patients with neuromuscular disorders had a similar mortality curve as head and neck cancer patients. Stroke/CNS tumor patients and patients with other indications had the second highest mortality, while trauma patients had low mortality., Conclusions: PEG mortality was much higher in patients with malignancies other than head and neck cancer compared to previously published rates. PEG should be used with great caution in this and other high-risk patient groups. This study demonstrates the power of an EDW-based database to evaluate large numbers of patients with clinically meaningful results.
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- 2013
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19. The chosen few: disproportionate resource use in ventral hernia repair.
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Poulose BK, Beck WC, Phillips SE, Sharp KW, Nealon WH, and Holzman MD
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- Databases, Factual, Female, Health Resources economics, Hernia, Ventral economics, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Risk Factors, United States, Health Resources statistics & numerical data, Hernia, Ventral surgery, Herniorrhaphy economics, Hospital Charges statistics & numerical data
- Abstract
The objectives of this study were to determine if disproportionately small numbers of patients use more resources for ventral hernia repair (VHR) and to identify factors associated with this group. Patients undergoing VHR were identified using national 2009 Healthcare Cost and Utilization Project data. Mean total hospital charges (THCs) were calculated and patients were divided into high charges (HC, greater than 50% mean THC) and low charges (LC, 50% or less mean THC) groups. Multivariate analysis was used to identify factors associated with the HC group. We estimated 181,000 hospitalizations for VHR in 2009 with mean THC of $54,000. Fifteen per cent of patients comprised the HC group with 85 per cent in the LC group. The HC group had higher THC ($173,000 vs $32,000; P < 0.05), increased mean length of stay (16.0 vs 4.1 days, P < 0.05), and higher mortality (6.3 vs 0.6%, P < 0.05). Risk factors for HC included congestive heart failure (odds ratio [OR], 2.2; 95% confidence interval [CI], 2.0 to 2.5), chronic lung disease (OR, 1.3; 95% CI, 1.2 to 1.4), Asian race (OR, 2.5; 95% CI, 1.7 to 3.7), nonelective operation (OR, 1.9; 95% CI, 1.6 to 2.3), and male gender (OR, 1.2; 95% CI, 1.1 to 1.3). For inpatient VHR, a remarkably small proportion of patients use disproportionately high hospital resources. The identified risk factors can help surgeons predict patients who are likely to consume large amounts of resources.
- Published
- 2013
20. Comparative effectiveness of dynamic abdominal sonography for hernia vs computed tomography in the diagnosis of incisional hernia.
- Author
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Beck WC, Holzman MD, Sharp KW, Nealon WH, Dupont WD, and Poulose BK
- Subjects
- Comparative Effectiveness Research, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Hernia, Ventral diagnostic imaging, Tomography, X-Ray Computed, Ultrasonography methods
- Abstract
Background: Diagnosis and characterization of incisional hernia are often established by CT, which incurs radiation exposure and substantial cost in clinical practice. The purpose of this study was to determine the comparative effectiveness of surgeon-performed Dynamic Abdominal Sonography for Hernia (DASH) vs CT for incisional hernia evaluation., Study Design: Patients with previous abdominal operations and recent CT imaging were enrolled prospectively; patients with stomas, fistula, or soft tissue infection were excluded. In the clinic setting, DASH was performed with prerequisite training of the American College of Surgeons Ultrasound for Surgeons Basic Course. Clinical evidence of hernia, results of DASH examination, and radiologist documentation of incisional hernia were compared with the gold standard of surgeon-interpreted CT. Testing characteristics of sensitivity and specificity were compared and predictive values were calculated. Inter-rater reliability was performed by comparing DASH results in a subgroup of patients with 3 different evaluators., Results: There were 181 patients enrolled, with a mean age of 54 years, and 68% were women. In patients in whom hernias were identified, the mean hernia size was 44.6 cm(2) (range 0.2 to 468.3 cm(2)). The DASH examination showed high sensitivity (98%) and specificity (88%). Hernia prevalence was 55% in this population, resulting in positive and negative predictive values of 91% and 97%, respectively. Four patients had clinically detectable hernias that were not seen on CT but were discovered with DASH. Inter-rater reliability for DASH was high, with an observed intraclass correlation coefficient of 0.79., Conclusions: The DASH examination is an accurate alternative to CT scan for diagnosing abdominal wall hernias, with additional benefits of no radiation exposure and instant bedside interpretation. The use of DASH to detect hernia recurrence can greatly facilitate long-term follow-up of hernia patients., (Copyright © 2013 American College of Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
21. Achalasia.
- Author
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Beck WC and Sharp KW
- Subjects
- Catheterization methods, Esophagus surgery, Humans, Manometry, Morbidity trends, Pressure, United States epidemiology, Digestive System Surgical Procedures methods, Esophageal Achalasia diagnosis, Esophageal Achalasia epidemiology, Esophageal Achalasia therapy, Esophagoscopy methods, Esophagus physiopathology, Gastrointestinal Agents therapeutic use
- Abstract
This article reviews the diagnosis and treatment of achalasia, a rare esophageal motility disorder characterized by absent peristalsis and failure of the lower esophageal sphincter (LES) to relax. Various treatment options including management with sublingual nitrates or calcium channel blockers, injection of the LES with botulism toxin, pneumatic dilation of the LES, and pneumatic dilation are discussed. Laparoscopic Heller myotomy is minimally invasive with incumbent low morbidity and mortality rates, and combined with a partial fundoplication is a durable, safe, and effective treatment option for patients with achalasia., (Copyright © 2011 Elsevier Inc. All rights reserved.)
- Published
- 2011
- Full Text
- View/download PDF
22. Gown-glove interface: a possible solution to the danger zone.
- Author
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Meyer KK and Beck WC
- Subjects
- Humans, Gloves, Surgical, Infectious Disease Transmission, Patient-to-Professional prevention & control, Protective Clothing, Universal Precautions methods
- Abstract
The gown-glove interface is the weakest point in the present barrier system of gown and glove protection for the surgeon and other healthcare professionals who come into direct contact with body liquids. Try it yourself: put on a fluid-resistant gown and surgical gloves. See that the glove cuff is well proximal to the stockinette. Hold your wrist and forearm for a moment under running water. Wait a minute to see if your forearm is wet. A wet forearm during surgery would be a blooded one. We propose a gown redesign that creates a dart at the terminal forearm, sealed by a liquid-proof method, and then similarly sealing the proximal end of the glove to the sleeve.
- Published
- 1995
- Full Text
- View/download PDF
23. Effect of povidone iodine dermatologic ointment on wound healing.
- Author
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Kashyap A, Beezhold D, Wiseman J, and Beck WC
- Subjects
- Administration, Cutaneous, Animals, Cortisone adverse effects, Cortisone analogs & derivatives, Female, Hydroxyproline analysis, Mice, Ointments, Surgical Wound Infection pathology, Surgical Wound Infection prevention & control, Tensile Strength, Povidone-Iodine therapeutic use, Wound Healing drug effects
- Abstract
Objective: To evaluate the effect of topical povidone iodine ointment on wound healing., Materials and Methods: 60 female mice randomly divided into four groups, A-D. Each mouse had a 2 cm linear incision made on the dorsal skin. Group A had povidone iodine ointment, and group B had ointment base applied for 7 days to the healing incision. Group C were given steroids for 7 days, and group D were allowed to heal without treatment. On Day 8, the strength of the incision was tested with an in vivo tensometer, and the hydroxyproline content of the incision was determined., Results: Using ANOVA and Fischer's LSD test (P < 0.05), povidone iodine as well as steroid groups had significantly reduced wound strengths as compared to the controls and the group with ointment base. No significant difference in the hydroxyproline content was seen., Conclusions: Povidone iodine significantly reduces wound strength without reducing the total hydroxyproline content of the wound.
- Published
- 1995
24. Divide and conquer--protection, comfort, and cost of the surgeon's gown.
- Author
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Beck WC, Belkin NL, and Meyer KK
- Subjects
- Costs and Cost Analysis, Protective Clothing economics, General Surgery, Infection Control, Protective Clothing standards
- Published
- 1995
- Full Text
- View/download PDF
25. Starch glove powder should follow talc into limbo.
- Author
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Beck WC and Beezhold DH
- Subjects
- Humans, Rubber, Talc, Gloves, Surgical, Powders adverse effects
- Published
- 1994
26. Barrier breach of surgical gloves.
- Author
-
Beck WC
- Subjects
- Equipment Failure, Humans, General Surgery, Gloves, Surgical standards, Infection Control methods, Occupational Exposure
- Abstract
The barrier properties of natural rubber latex gloves have been of clinical interest since the concept of using an integrity monitor was introduced by me over 30 years ago. Although surgeons expect their gloves to serve as an effective barrier during use, products can and do fail. Failure is often unrecognized, resulting in the wearer's exposure to potential pathogens and the patient to microorganisms shed by surgical team members. Although a variety of solutions have been suggested (double gloving, cut-resistant gloves), these remedies do not alert the surgeon to a breach of barrier, the cost and consequences of which are astronomical to the health system. As a result, some form of breach detection device is now recommended to minimize the likelihood of exposure, infection, and/or allergy.
- Published
- 1994
27. Flash sterilization and instrument tape--an experimental study.
- Author
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Kostyal DA, Verhage JM, Beezhold DH, and Beck WC
- Subjects
- Evaluation Studies as Topic, Humans, Sterilization methods, Surgical Instruments standards, Equipment Contamination prevention & control, Operating Rooms standards, Sterilization standards
- Abstract
A letter appearing in the AORN Journal questioned whether flash sterilization is appropriate for instruments coded with color identification tape. The reply stated that porous, colored tape required a longer time to penetrate and sterilize the area beneath, and thus if it should peel off, the zone beneath might not be sterile. This conclusion was, as far as we can determine, reached by intuitive reasoning and not by experimental evidence. Therefore, the following experimental approach was undertaken to test the hypothesis. Spores on discs were placed between the color-code tape and a metal instrument. Exposure to heat (135 degrees C) and time (3 min.) was in a gravity displacement sterilizer. We then determined whether spore kill has been achieved. The test organism was B. stearothermophilus. None of the discs that were in contact with the instruments while being sterilized showed any growth. Thus, it appears that sterility can be achieved on the instrument surfaces that are beneath color-code tape in three minutes.
- Published
- 1993
28. Barrier testing methods.
- Author
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Beck WC
- Subjects
- Humans, Infection Control standards, Protective Clothing standards
- Published
- 1993
- Full Text
- View/download PDF
29. Surgical glove powders bind latex antigens.
- Author
-
Beezhold D and Beck WC
- Subjects
- Adsorption, Animals, Antigens metabolism, Blotting, Western, Disease Models, Animal, Drug Hypersensitivity blood, Drug Hypersensitivity etiology, Electrophoresis, Polyacrylamide Gel, Enzyme-Linked Immunosorbent Assay, Evaluation Studies as Topic, Humans, Immune Sera, Latex metabolism, Powders, Protein Binding, Rabbits, Starch immunology, Starch metabolism, Antigens immunology, Drug Hypersensitivity immunology, Gloves, Surgical standards, Latex adverse effects, Starch adverse effects
- Abstract
Latex surgical gloves have recently been identified as a potential source of allergens. Much of the current information suggests that the soluble proteins in latex may cause significant reactions in sensitive individuals. The starch powders used as a lubricant on some latex gloves have also been identified as potential allergens in some patients. In this study, we determined these powders to act as potential carriers of latex allergens. We have produced a polyclonal antiserum to be used as a reagent to study latex proteins. By Western blot analysis, we identified a significant interaction between latex proteins and starch powders. The binding of latex proteins to starch particles results in a glove particle that may have an increased potential to act as an allergen. The latex protein-starch particles represent a potential mechanism for exposure and sensitization of health care workers to latex allergens. Elimination of these particles from the operating room should reduce the route of sensitization and the potential for adverse reactions to latex.
- Published
- 1992
- Full Text
- View/download PDF
30. Issues related to surgical gloves.
- Author
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Beck WC
- Subjects
- History, 19th Century, History, 20th Century, Powders, Starch, Gloves, Surgical history, Infection Control
- Published
- 1992
31. The surgical mask: another 'sacred cow'?
- Author
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Beck WC
- Subjects
- Humans, Masks, Surgical Wound Infection prevention & control
- Published
- 1992
- Full Text
- View/download PDF
32. Glove tears and sharp injuries in surgical personnel.
- Author
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Beck WC
- Subjects
- Equipment Failure, Humans, Needlestick Injuries, Accidents, Occupational, General Surgery, Gloves, Surgical standards, Wounds, Stab
- Published
- 1992
- Full Text
- View/download PDF
33. Protecting the index finger during surgery.
- Author
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Beck WC
- Subjects
- Humans, Accidents, Occupational prevention & control, Finger Injuries prevention & control, Protective Devices, Surgical Procedures, Operative
- Published
- 1991
34. Acute appendicitis. A 5-year review.
- Author
-
Ricci MA, Trevisani MF, and Beck WC
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Appendectomy adverse effects, Appendicitis complications, Appendicitis pathology, Child, Child, Preschool, Female, Humans, Incidence, Infant, Intestinal Perforation complications, Intestinal Perforation pathology, Male, Middle Aged, Pennsylvania epidemiology, Peritonitis etiology, Rupture, Spontaneous, Appendicitis epidemiology, Intestinal Perforation epidemiology
- Abstract
A startling 31 per cent rate of perforated appendicitis in 1984 prompted a 5-year review at the Guthrie Medical Center. An increase over previous rates of 13 per cent and 0 per cent in 1964 and 1944 was confirmed in this study. Perforation accompanied 44 of 240 cases of appendicitis (18.3%); diagnostic accuracy in 295 cases undergoing operation was 81.4 per cent. Groups at risk for perforation were patients in the first decade of life (34.3% with perforations) and those over 50 years of age (48% perforated). Perforation rates were generally inversely related to accuracy. Accuracy was poorest in women in the second to fourth decade or those in the mid-portion of the menstrual cycle. When the appendix was not perforated, complications occurred in 8.7 per cent of patients while 29.5 per cent with a perforation had a complication. The mean hospital stay was prolonged by 2.5 days if the appendix was perforated. An increased awareness of the risk by both the public and physicians is essential to reduce the number of perforations.
- Published
- 1991
35. Asepsis plus/minus comfort.
- Author
-
Beck WC
- Subjects
- General Surgery methods, General Surgery standards, Humans, Protective Clothing supply & distribution, Asepsis standards, General Surgery organization & administration, Protective Clothing standards
- Published
- 1991
36. Medical waste. The growing issues of management and disposal.
- Author
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Fay MF, Beck WC, Fay JM, and Kessinger MK
- Subjects
- Humans, Refuse Disposal legislation & jurisprudence, Refuse Disposal standards, United States, Medical Waste, Refuse Disposal methods, Waste Products
- Abstract
When addressing the impact of medical waste management and regulatory controls on the health care industry, it is important to remember that as long as modern medicine continues to maintain and sustain its current quality of life and wellness standards, industry will continue to generate various byproducts that have adverse effects on both people and the environment. It is important, therefore, to carefully evaluate the impact of societal demands. Unless government, industry, environmental groups, and health care providers abandon their current adversarial relationships and work together to solve shared problems, there will be no improvement in the growing problem of medical waste. The long-term solutions to today's growing waste problems depend to a great extent on human factors and the willingness of industry, medical community, and governmental bodies to cooperate with each other, recognizing the cause-effect relationship of a continued demand for disposable products. There are many pieces to the waste management puzzle. Obviously, surgeons cannot perform surgery without exposure to blood, tissue or body fluids, and nurses cannot maintain asepsis without sterile products. Because the health care team cannot totally eliminate the source of medical waste, they must learn to more effectively manage and control it. Health care professionals must encourage industry and government to work together to develop standards for products and materials used as barriers and use more biodegradable materials. Health care facilities must learn to minimize the amount of medical waste designated as regulated or infectious. Segregating potentially infectious material from clean waste at the point of generation may reduce both volume and cost.
- Published
- 1990
- Full Text
- View/download PDF
37. Pimping.
- Author
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Beck WC
- Subjects
- Internship and Residency, Social Dominance, Terminology as Topic
- Published
- 1990
38. Effect of vitamin A and zinc on wound healing in steroid-treated mice.
- Author
-
Trevisani MF, Ricci MA, Tolland JT, and Beck WC
- Subjects
- Animals, Cortisone pharmacology, Female, Mice, Tensile Strength drug effects, Cortisone analogs & derivatives, Vitamin A pharmacology, Wound Healing drug effects, Zinc pharmacology
- Published
- 1987
39. Technology and group diseases: treatment calls for planning, consultative approach.
- Author
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Beck WC, Bednarek T, and Weaver D
- Subjects
- Humans, Patient Care Team, Referral and Consultation, Therapeutics, United States, Disease classification, Patient Care Planning, Technology, Radiologic
- Published
- 1980
40. Benefits of alcohol rediscovered.
- Author
-
Beck WC
- Subjects
- Humans, Preoperative Care, Alcohols, Anti-Infective Agents, Local, Disinfectants
- Published
- 1984
- Full Text
- View/download PDF
41. Handwashing substitute for degerming.
- Author
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Beck WC
- Subjects
- Humans, Disinfectants, Hand microbiology
- Published
- 1978
- Full Text
- View/download PDF
42. Surgical glove perforation.
- Author
-
Beck WC
- Subjects
- Equipment Failure, Gloves, Surgical standards
- Published
- 1989
- Full Text
- View/download PDF
43. Sterilization of anesthetic apparatus.
- Author
-
Beck WC
- Subjects
- Female, Humans, Anesthesia, Epidural adverse effects, Anesthesia, Obstetrical adverse effects, Bupivacaine adverse effects, Seizures chemically induced
- Published
- 1978
44. Choosing surgical illumination.
- Author
-
Beck WC
- Subjects
- General Surgery, Lighting, Operating Rooms
- Abstract
(1) Lighting systems for the surgical task are combinations of ambient room lighting to complement the operating task light. The two must match to produce a good effect. (2) Only a few surgical task lights are available, and their characteristics and relative merits should be studied. (3) Ideally the surgeon should test the task light to judge its suitability for his taste.
- Published
- 1980
- Full Text
- View/download PDF
45. Alcohol foam has a place in the clinical arena.
- Author
-
Beck WC
- Subjects
- Humans, 1-Propanol therapeutic use, Hand Disinfection methods, Health Occupations
- Published
- 1989
- Full Text
- View/download PDF
46. Organizational responsibilities in the control of surgical infection.
- Author
-
Beck WC
- Subjects
- Hospital Administration, Humans, Manuals as Topic, General Surgery, Surgical Wound Infection prevention & control
- Published
- 1977
47. Abridged sterility--a level of disinfection.
- Author
-
Beck WC
- Subjects
- Disinfection, Sterilization
- Published
- 1977
- Full Text
- View/download PDF
48. Gloves. Manufacturers respond to cost containment ... glove usage.
- Author
-
Fay MF and Beck WC
- Subjects
- United States, Catalogs, Commercial as Topic, Gloves, Surgical standards, Hospitals
- Published
- 1987
49. A consultation with Dr. Dominique-Jean Larrey.
- Author
-
Beck WC
- Subjects
- France, History, 19th Century, Military Medicine history
- Published
- 1979
50. Postoccupancy evaluation of a surgical suite.
- Author
-
Fitzgerald H and Beck WC
- Subjects
- Evaluation Studies as Topic, Surveys and Questionnaires, Operating Rooms standards
- Published
- 1979
- Full Text
- View/download PDF
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