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1,565 results on '"Beck, Roy W."'

1. Associations between daily step count classifications and continuous glucose monitoring metrics in adults with type 1 diabetes: analysis of the Type 1 Diabetes Exercise Initiative (T1DEXI) cohort

Author

Turner, Lauren V., Marak, Martin Chase, Gal, Robin L., Calhoun, Peter, Li, Zoey, Jacobs, Peter G., Clements, Mark A., Martin, Corby K., Doyle, III, Francis J., Patton, Susana R., Castle, Jessica R., Gillingham, Melanie B., Beck, Roy W., Rickels, Michael R., and Riddell, Michael C.

Published
2024
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2. Complications, Visual Acuity, and Refractive Error 3 Years after Secondary Intraocular Lens Implantation for Pediatric Aphakia

Author

Freedman, Sharon F., Wallace, David K., Enyedi, Laura B., Prakalapakorn, Sasapin, Jones, Sarah K., Hug, Denise, Stahl, Erin D., Dent, Rebecca J., Kong, Lingkun, Wang, Serena, Gallerson, Bryan K., Hutchinson, Amy K., Lenhart, Phoebe, Brower, Judy, Morrison, David G., Ruark, Scott T., Mets-Halgrimson, Rebecca, Yoon, Hawke, Ralay-Ranaivo, Hantamalala, Hamidullah, Aaliyah, Areaux, Raymond, Anderson, Jill S., Holleschau, Ann M., Superstein, Rosanne, Belanger, Caroline, Fallaha, Nicole, Hamel, Patrick, Thibeault, Maryse, Tamkins, Susanna M., Chang, Ta, Park, Hee-Jung S., Trumler, Anya A., Liu, Xiaonong, Astle, William F., Sanders, Emi N., Traboulsi, Elias, Ghasia, Fatema, McOwen, Diana C., Gray, Michael E., Yang, Michael B., Bowman, Corey S., Galvin, Jennifer, Therriault, Margaret, Smith, Heather, Whitaker, Michele E., Orge, Faruk, Grigorian, Adriana P., Baird, Alicia M., Strominger, Mitchell B., Chen, Vicki, Klein, Shelley, Kemmer, Jacquelyn D., Neiman, Alexandra E., Mendoza, Myra N., Frohwein, Jill J., Bremer, Don, Cassady, Cybil, Golden, Richard, Jordan, Catherine, Rogers, David, Oravec, Sara A., Yanovitch, Tammy L., Lunsford, Keven, Nye, Christina, Shea, Caroline, Stillman, SueAnn M., LaRoche, G. Robert, Van Iderstine, Stephen C., Robertson, Elisa, Cruz, Oscar A., Ghadban, Rafif, Govreau, Dawn, Larson, Scott A., Longmuir, Susannah, Shan, Xiaoyan, Clarke, Michael P., Taylor, Kate, Powell, Christine, Hammond, Benjamin P., Gearinger, Matthew D., Czubinski, Andrea, Hendricks, Dorothy H., Jin, Jing, Salvin, Jonathan H., Fisher, Alicia, Lee, Katherine A., Brooks, Daniel, Schweinler, Bonita R., Sala, Nicholas A., Sala, Allyson M., Summers, Allison I., Karr, Daniel J., Wilson, Lorri B., Rauch, Paula K., O'Hara, Mary, Gandhi, Nandini, Hashmi, Tania, Colburn, Jeffrey, Dittman, Eileen, Whitfill, Charles R., Wheeler, Amy M., McCourt, Emily A., Singh, Jasleen, Welnick, Nanastasia, Azar, Nathalie F., Baker, Joseph, Droste, Patrick J., Peters, Robert J., Hilbrands, Jan, Pineles, Stacy L., Bernardo, Marianne J., Peterson, Edward, Peterson, Charla H., Kumar, Kartik, Melese, Ephrem, Lingua, Robert, Grijalva, Jeff, Crouch, Earl R., jr., Crouch, Earl R., III, Ventura, Gaylord, Anninger, William, Benson, Shawn L., Karp, Karen A., Smith, Jordana M., Brickman-Kelleher, Jill, Ticho, Benjamin H., Khammar, Alexander J., Clausius, Deborah A., Guo, Suquin, Suh, Donny, Chamberlain, Carolyn, Schloff, Susan, Madigan, William P., Burkman, Donna, Christiansen, Stephen P., Ramsey, Jean E., McConnell, Kate H., Friedman, Ilana, Rosado, Jose, Sauberan, Donald P., Hemberger, Jody C., Davis, Patricia L., Rudaitis, Indre, Lowery, Robert S., Cupit, Shawn, Bothun, Erick D., Mohney, Brian G., Wernimont, Suzanne M., Neilsen, Rebecca A., Herlihy, Erin P., Baran, Francine, Gladstone, Amy, Smith, Justin, Mellott, Mei, Kieser, Troy, Erzurum, S. Ayse, Colon, Beth, Shah, Birva, Quebbemann, Micaela, Beck, Roy W., Austin, Darrell S., Boyle, Nicole M., Conner, Courtney L., Chandler, Danielle L., Donahue, Quayleen, Fimbel, Brooke P., Robinson, Julianne L., Hercinovic, Amra, Hoepner, James E., Kaplon, Joseph D., Henderson, Robert J., Melia, B. Michele, Ortiz, Gillaine, Woodard, Victoria C., Stutz, Kathleen M., Sutherland, Desirae R., Wu, Rui, Everett, Donald F., Diener-West, Marie, Baker, John D., Davis, Barry, Phelps, Dale L., Poff, Stephen W., Saunders, Richard A., Tychsen, Lawrence, Bradfield, Yasmin S., Foster, Nicole C., Plager, David A., Salchow, Daniel J., Birch, Eileen E., Manny, Ruth E., Silver, Jayne L., Weise, Katherine K., Verderber, Lisa C., Repka, Michael X., Dean, Trevano W., Kraker, Raymond T., Li, Zhuokai, Yen, Kimberly G., de Alba Campomanes, Alejandra G., Young, Marielle P., Rahmani, Bahram, Haider, Kathryn M., Whitehead, George F., Lambert, Scott R., Kurup, Sudhi P., Kraus, Courtney L., Cotter, Susan A., Holmes, Jonathan M., Hatt, Sarah R., and Traboulsi, Elias I.

Published
2024
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4. Home OCT Imaging for Newly Diagnosed Neovascular Age-Related Macular Degeneration: A Feasibility Study

Author

Glassman, Adam R., Beck, Roy W., Baptista, Alyssa, Beaulieu, Wesley T., Calhoun, Claire T., Constantine, Sharon R., Dale, Brian B., Dupre, Simone S., Franklin, Crystal A., Galusic, Sandra, Huggins, Meagan, Hunter, Brenda L., Johnson, Paula A., Josic, Kristin, Kelly, Brittany, Liu, Danni, Maguire, Maureen G., Meadows, Britney, Melia, Michele, Preston, Carin M., Stockdale, Cynthia R., Zokruah, Alice, Sun, Jennifer K., Martin, Daniel F., Bhargava, Sangeeta, Barkmeier, Andrew J., Baskin, Darrell, Blodi, Barbra, Chew, Emily, Ferris, Frederick L., III, Jaffe, Glenn J., Jampol, Lee M., Jhaveri, Chirag D., MacCumber, Mathew, Maturi, Raj K., Solomon, Sharon D., Antoszyk, Andrew N., Lujan, Brandon, Slahi-Had, Hani, Lane, Richard Gary, Adams, Lydia, Rivera, Rachel R., Nakoski, Brenda, Weeks, Rhonda F., Braverman, Allan L., McDonald-Mueller, Lauren, Stuart, Maria A., Pulliam, Brook G., Boyd, Lynda K., Wehmeier, Jarrod, Schremp, Steve A., Googe, Joseph M., Oliver, Kristina, Walsh, Justin, Asher, Julie, Milstead, Katie, Wheeler, Jeff, Griffone, Hodge A., Blinder, Kevin J., Calhoun, Claire, Mein, Calvin E., Baskin, Darrell E., Vieyra, Gabriela, and Chica, Moises A.

Published
2024
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6. Assessment of Baseline Ultrawidefield Fluorescein Angiographic Quantitative Leakage Parameters with Ultrawidefield Fundus Features and Clinical Parameters in Diabetic Retinopathy in Protocol AA

Author

Harara, Abla M., Palacios, Angela N., Berger, Brian B., Corak, Boris, Luong, Bianca, Jhaveri, Chirag D., Wilson, Daniela Mariel, Jonna, Gowtham, Gunderson, Ivana, Hosein, Kimberly, Reid, Ryan M., Chexal, Saradha, Moore, Tori, Seidu, Tina A., Gatavaski, Valerie, Ren, Yong, Stern, Bradley A., Benvenutti, Celia E., Oude-Reimerink, Dinah S., Shaheen, Jenny, Grybas, John, Vitale-Kuhn, Julianne, Staffne, Jessica L., Ventimiglia, Katie M., Allis, Megan, Monk, Mary K., Thomas, Marc E., Massu, Nicole M., Edwards, Paul Andrew, Troszak, Tracy A., Irons, Amber N., Rego, Brittany, Han, Dennis P., Dorsey, Eleanor, Nelson, Erika, Sheppard, Hannah, Beringer, Joseph R., Kim, Judy E., Keller, Kristy L., Packard, Krissa L., Altmann, Marriner L., Goldberg, Mara, Chen, Nickolas, Winter, Pat A., Bourgeois, Shay, Jacobo, Samantha, Moebius, Stephanie J., Connor, Thomas B., Barwick, Vicki, Williams, Vesper V., Wirostko, William J., Ghuman, A. Thomas, Leslie, Anita H., Sharma, Ashish G., Kiesel, Cheryl, Dyshanowitz, Danielle, Knips, Eileen, Wing, Glenn, Walker, Joseph P., Raskauskas, Paul A., Kiesel, Raymond K., Schlossman, Deborah K., Weimann, Elizabeth S., Sharuk, George S., Kwak, Hanna, Cavallerano, Jerry D., Rhee, Jae W., Sampani, Konstantina, Tran, Katie V., Bestourous, Leila, Miranda, Linette, Krigman, Michael N., Stockman, Margaret E., Arrigg, Paul G., Cavicchi, Robert W., Kirby, Rita K., Glynn, Shireen, Papaconstantinou, Steve L., Shah, Sabera T., Murtha, Timothy J., Carli, William, Finch, Autumn K., Gentile, Angella K., Price, Angela K., Murphy, Brittany A., Rowland, Beverly O., Fleming, Christina J., Mahr, Courtney, Shore, Carol A., Browning, David, McClain, Donna, Breglio, Erica, Lester, Gina M., Herby, Jenna T., Bratcher, Kayla A., Clark, Loraine M., Jackson, Lisa A., Watson, Lynn, McOwen, Michael D., Punjabi, Omar S., Bojaj, Swann J., Ennis, Sarah A., Fredenberg, Sherry L., Jones, Taylor S., Ragin, Teneisha A., Balasubramaniam, Uma M., Ornelas, Blanca, Rodriquez, Brenda, Edwards, Carla, Carns, Danielle R., Tonner, Eileen E., Woo, Kisung, Richine, Len, MacCumber, Mathew W., Merrill, Pauline Townsend, Kociborski, Sarah, Harless, Ashley M., Harris, Charlotte, White, Lorraine, Maturi, Raj K., Asher, Julie, Walsh, Justin, Wheeler, Jeff, Milstead, Katie, Oliver, Kristina, Lovelady, Lisa, Anderson, Nicholas G., Coppola, Patricia, Lince, Raul E., Shuler, R. Keith, Morris, Steve, Oelrich, Sarah M., Gardner, Brandon S., Moore, Bob, Cain, Dennis, Donohue, Deborah, Emmert, David, Adeyemo, Kemi, Levin, Lisa K., Frey, Mary, Rhoton, Nick, Bressler, Susan, Solomon, Sharon D., Ford, Amy L., Hughes, Ashley, Brewer, Alisha N., Booth, JoAnn T., Lunsford, Keven W., Ukleya, Lauren D., Burris, Russ, Kingsley, Ronald M., Almeida, Shannon R., Icks, Sonny, Shah, Vinay A., Bergman, Vanessa A., Castellarin, Alessandro A., Shook, Aimee H., Walker, Aimee, Pieramici, Dante J., Hong, Gina, Avery, Kelly, McKee, Kate M., Giust, Matthew, Munoz, Marco A., Fishbein, Sarah, Camp, Alecia B., Baker, Carl W., Baker, Jil D., Sedberry, Kylie S., Lambert, Lynnette F., Orr, Margaret J., Alcaraz, Sonya L., Kettler, Samantha, Caldwell, Tracey M., Miller, Abigail, Dorr, Christine M., Hampton, G. Robert, Brown, Jamin S., Barker, Jeffrey P., Rosenberg, Kevin I., Kwasniewski, Lynn M., Sienkiewycz, Laurie J., Spuches, Lisa, Manley, Michelle L., Robarge, Nicole E., DeSantis, Stefanie R., DeForge, Teresa M., Brucker, Alexander J., Kim, Benjamin J., Berger, Jim M., DuPont, Joan C., Drossner, Sheri, Freeman, Sara, Studebaker, Ashley, Payne, John F., Wells, John A., Spivey, Robbin, Ogbuewu, Tiffany N., Swinford, Tiffany R., Guillory, Adrienne, Hutson, Amy, Schefler, Amy C., Shah, Ankoor R., Almanza, Belinda A., Dives, Brenda, Richter, Beau A., Stoever, Cary A., Brown, David M., Foerster, Danee, Garcia, David, Rodriguez, Diana, Park, Daniel, Chen, Eric, Kegley, Eric N., Quellar, Elizabeth, Twining, Garret L., Koger-Grifaldo, Heather, Ortega, Ilsa, Carranza, Jolene, Major, James C., Williamson, Kimberly, Burt, Lindsay, Salinas, Luis R., Wolff, Lisa M., Benz, Matthew S., Estes, Maura A., James, Miranda F., Berry, Meredith, Vela, Melina, Landaverde, Nubia, Webb, Nina A., Fish, Richard H., Kim, Rosa Y., Yee, Rebecca, Karani, Sadia Y., Supapo, Stacy M., Dodel, Tamara L., McCoy, Tyneisha, Wong, Tien P., Sneed, Veronica A., Barnhart, Cassandra J., Cantrell, Debra, DuBose, Elizabeth L., Sharpe, Houston P., Ulrich, Jan Niklas, Bhansali, Kanika A., Esquejo, Rona Lyn, Garg, Seema, Grout, Sean, McKinney, Allen, Bobbitt, Brenda J., Wendel, Ceara L., Fagan, Damanda F., Andrews, Jacqueline, Holmes, Krystal Nikki, Seyez, Karen L., Williamson, Kimberly A., Moinfar, Nader, Walters, Paige N., Carlton, Steve, Rehling, Shannon M., Williams, Shana E., Reed, Tiara L., VandeVelde, Amber R., Yeager, Frank T., Fox, Gregory M., Batlle, Ivan R., Bruce, Kiersten, Pippin, Katherine, Ainley, Lexie R., Singh, Ravi S.J., Adamo, Ashley M., Guardado, Adrian, Patel, Apurva K., Puckett, Brian S., Hoerner, Christine, Ma, Colin, Clark, David J., Flato, Inessa M., Cohen, Joshua, Charpentier, Margaret E., Kopfer, Marcia, Peters, Mark A., Smith, Pualani, Tlucek, Paul S., Hobbs, Stephen, Ho, Stephanie L., Metzger, Ashley M., McCalla, Alesia K., Thompson, Amy, Ringrose, Christine, Sandler, Dallas R., Leder, Henry A., Belz, Jennifer L., Starr, JoAnn, Simmons, Jennifer L., Orr, Peggy R., Sotirakos, Peter, Singletary, Pamela V., Cain, Terri, Coffey, Teresa, Carter, Tiffany M., Robinson, Twyla J., Shah, Chirag P., Cammarata, Dominique, Kruger, Jennifer L., Colegrove, Lindsey, Graham, Margie, Gleason, Shane T., Noel, Bryan, Damron, Catherine, Holcomb, Diana M., Slade, Edward A., Van Arsdall, Jeanne, Bicknell, Lisa, Buck, Michelle, Stone, Thomas W., Farooq, Amina, Parsons, Brook, Singh, Harinderjit, Ivey, Ken, Foster, Lindsay Allison, Woodward, Michele, Ortiz, Siobhan O., Bailey, Thomas, Mynampati A, Bharani Krishna, White, Cheryl L., Hamdani, Ghulam Shabbir, Smith, Jazzmin N., Chalam, Kakarla V., Sambhav, Kumar, Babaria, Romesh, Grover, Sandeep, Carroll, Catherine, Chau, Felix Y., Lim, Jennifer I., Talasnik, Lauren A., Janowicz, Mark, Stankovic, Natasa, Berlatsky, Sarah L., Niec, Marcia, Sun, Jie, Johnson, Tametha, Ovando, Yesenia, Nakoski, Brenda, Mein, Calvin E., Wienecke, Christopher Sean, Castillo, Elaine, Baker, Jaynee, San Roman, Jonathan, Adams, Lydia, Kirschbaum, Lita, Chica, Moises A., Cloudt, Sara L., Moore, Tori R., Sabates, Felix N., Gallimore, Gary S., Chen, Yin C., Swann, Adrienne C., Cadwell, Deborah M., Diddie, Kenneth R., Boisvert, Taryn F., Tessau, Carrie D., Bowers, Jack, Nielsen, Jared S., Rostvold, Jay, Spillman, Jamie, Alliman, Kyle J., Boender, Lisa M., Johnson, Marilyn A., Parker, Marianne, Bix, Paula L., Ridgway, Spencer D., Woehl, Tami Jo, Stonewall, Whitney, Brown, Christopher M., Lema, Gareth M.C., Wiechelt, Luann, Yoganathan, Pradeepa, Boglione, Sandra L., Montesclaros, Chris A., Mangham, Cory, Karsaliya, Gopal, Le, Phillip V., Wong, Robert W., Godfrey, Anne Marie, Kuzmanovic, Aleksandra, Kirker, Andrew William, Harrison, Bryan, Forooghian, Farzin, Elvena, Garnet Louise, Hall, Laura J., Turhal, Bilgin, Brown, Ian, Kotei, Isaac A., Chen, Lina, Brent, Michael Henry, Moon, Michelle, Sutakovic, Olivera, Chang, Angela, Godfrey, Anne-Marie, Albiani, David, Maberley, David A.L., Navajas, Eduardo Vitor, Grant, Kelly, Tran, Khoi A., Jovanovic, Mira, Cao, Sijia, Wiens, Theresa, Kozbial, Andrzej, Orlin, Anton, Lenane, Courtney Nichole, Herder, Susan P., Kiss, Szilard, Reeves, Tom, Cruess, Alan F., Dean, Andrea, Hoskin-Mott, Ann, Morrison, Christine, Caldwell, Meggie D., Hynes, Mitzi, Gupta, R. Rishi, Durling, Stacey, MacDonnell, Trina, Beck, Roy W., Baptista, Alyssa, Beaulieu, Wesley T., Calhoun, Claire T., Constantine, Sharon R., Correia, Isabella, Dale, Brian B., Dupre, Simone S., Franklin, Crystal A., Galusic, Sandra, Huggins, Meagan, Hunter, Brenda L., Johnson, Paula A., Josic, Kristin, Kelly, Brittany, Maguire, Maureen G., Meadows, Britney, Stockdale, Cynthia R., Zokruah, Alice, Bhargava, Sangeeta, Barkmeier, Andrew J., Baskin, Darrell, Blodi, Barbra, Chew, Emily, Ferris, Frederick L., Jaffe, Glenn J., Bressler, Neil M., Lujan, Brandon, Tolls, Dorothy, Sheridan, Daniel, Pitoc, Cloyd M., Anne C Aquino, Lizzie, Salva, Claude Michael G., Lewis, Drew, Stainback, Jeffery, Makkena, Vijaya, Winter, Katrina, Mora, Adiel, Harrington, Chris, Vinh, Doc-Lap, Ehlers, Justis P., Yordi, Sari, Martin, Alison, Srivastava, Sunil K., and Sun, Jenifer K.

Published
2024
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7. Eight-Year Outcomes of Bilateral Lateral Rectus Recessions versus Unilateral Recession-Resection in Childhood Basic-Type Intermittent Exotropia

Author

Miller, Aaron M., Olvera, Maria N., Alexander, Monsey L., Curtin, Kathleen Mary, Dillon, Angela C., Gray, Carole L., Jackson, Jorie L., Qadir, Ximena V., Ramos, Cynthia R., Paysse, Evelyn A., Coats, David K., Yen, Kimberly G., Romany, Gihan, Homann, Melynda J., Kong, Lingkun, Law, Christine, Churchill, Sarah, MacSween, Lesley E., Hoover, Darren L., Huston, Pamela A., Racan, Pamela M., Soros, Kari E., Sala, Nicholas A., Sala, Nicholas Anthony, Johnson, Catherine, Sala, Allyson, Zeto, V. Lori, Donahue, Sean P., Wilkins, Carsyn Saige, Biernacki, Ronald J., Campbell, Megan K., Fraine, Lisa A., Ruark, Scott T., Crouch, Eric, Crouch, Earl R., Jr., Ventura, Gaylord G., Fritz, Carolina Andrea, Anderson, Jill S., Areaux, Raymond G., Jr, Holleschau, Ann M., Harder, Jessica Ann, May, Laura M., Merrill, Kim S., Schweigert, Anna I., Petersen, David B., Pickens, Tori S., McMurtrey, J. Ryan, Morrell, Beth A., Repka, Michael X., Liu, Xiaonong, Christoff, Alex, Silbert, David I., Modjesky, Heather, Woodall, Hayley L., Summers, Allison I., Kuo, Annie F., Wilson, Lorri B., Rauch, Paula, Lee, Jessy, Casey, Grant A., Narain, Srianna, Woodruff, Kevin, Ticho, Benjamin H., Clausius, Deborah A., Allen, Megan, Quebbemann, Micaela N., Shah, Birva K., Bothun, Erick D., Holmes, Jonathan M., Mohney, Brian G., Wernimont, Suzanne M., Czaplewski, Lindsay L., Eastman, Stacy L., Huisman, Jordan Joseph, Klaehn, Lindsay D., Kramer, Andrea M., Kroening, Rose M., Priebe, Debbie M., Wohlers, Moriah A., Jensen, Allison A., Flanagan, Maureen A., Tolbert, Tiffany Talia, Traboulsi, Elias, Ghasia, Fatema F., Meador, Angela M., McOwen, Diana Christine, Enyedi, Laura B., Jones, Sarah K., Kashyap, Namita, Loud, Rachel N., Waters, Amy L., Marsh, Justin D., Bond, Lezlie L., Ariss, Michelle M., Dent, Rebecca J., Phillips, Paul H., Lowery, Robert Scott, Haley, Wendy Jean, Brown, Shaina, Colon, Beth, Cupit, Shawn L., Holtorf, Hannah L., Sanders, Hayley Elizabeth, Bowsher, James D., Cheeseman, Edward W., Weas, Nikki M., Bradham, Carol U., Rahmani, Bahram, Ranaivo, Hantamalala Ralay, Cruz, Karla G., De Leon, Erika A., Klauer, Anthony Jeffrey, Tzanetakos, Vivian, McCoy Vrablec, Laura, Orge, Faruk H., Richards, Leslie, Baird, Alicia Marie, Glaser, Stephen R., Yost, Kasey L., Flores, Odalis R., Herlihy, Erin P., Taira, Alyssa, Alexander, Jessica, Gladstone, Amy, Kiens, Bridget Ann, Tews, Lyndsey A., Whitehead, George F., Shea, Caroline J., Stillman, SueAnn Marie, Nye, Christina N., Bartiss, Michael John, McGaw, Tennille F., Davis, Patricia L., Hulett, Katie R., Twite, Jacqueline, Bradfield, Yasmin S., Adler, Angela M., Anderson, Kristin A., Kraker, Raymond T., Beck, Roy W., Austin, Darrell S., Boyle, Nicole M., Chandler, Danielle L., Connelly, Patricia L., Conner, Courtney L., Donahue, Quayle, Fimbel, Brooke P., Henderson, Robert J., Hoepner, James E., Kaplon, Joseph D., Melia, B. Michele, Ortiz, Gillaine, Robinson, Julianne L., Stutz, Kathleen M., Sutherland, Desirae R., Toro, David O., Woodard, Victoria C., Wu, Rui, Cotter, Susan A., Birch, Eileen E., Christiansen, Stephen P., Hatt, Sarah R., Leske, David A., Melia, Michele, O’Hara, Mary, Pang, Yi, Romanchuck, Kenneth, Tamkins, Susanna M., Wallace, David K., Wheeler, David T., Bhatt, Amit, Chen, Angela M., Cheung, Nathan L., Cobb, Patricia, Colon, Beth J., Crouch, Eric R., Dean, Trevano W., Erzurum, S. Ayse, Esposito, Christina A., Fang, Caroline C., Gray, Michael E., Gunton, Kammi B., Hopkins, Kristine B., Jastrzembski, Benjamin G., Jenewein, Erin C., Jordan, Catherine O., Kraus, Courtney, Kurup, Sudhi P., Lazar, Elizabeth L., Li, Zhuokai, Lorenzana, Ingryd, McDowell, Paula S., Morrison, Ann M., Morrison, David G., Nylin, Elyse, Parker, Sue M., Patel, Reena, Plaumann, Maureen D., Pollack, Karen, Raghuram, Aparna, Retnasothie, Dashaini V., Roberts, Tawna L., Scheiman, Mitchell M., Shah, Veeral S., Superstein, Rosanne, Titelbaum, Jenna R., Vricella, Marilyn, Yamada, Tomohiko, Astle, William F., Christian, Melanie L., Everett, Donald F., Freedman, Sharon F., Good, William V., Lambert, Scott R., Lee, Katherine A., London, Richard, Manh, Vivian M., Manny, Ruth E., Pineles, Stacy L., Rogers, David L., Schweinler, Bonita R., Silver, Jayne L., Suh, Donny W., Verderber, Lisa C., Weise, Katherine K., Diener-West, Marie, Baker, John D., Davis, Barry, Higgins, Rosemary D., Poff, Stephen W., Saunders, Richard A., and Tychsen, Lawrence

Published
2024
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8. Continuous glucose monitoring and metrics for clinical trials: an international consensus statement

Author

Battelino, Tadej, Alexander, Charles M, Amiel, Stephanie A, Arreaza-Rubin, Guillermo, Beck, Roy W, Bergenstal, Richard M, Buckingham, Bruce A, Carroll, James, Ceriello, Antonio, Chow, Elaine, Choudhary, Pratik, Close, Kelly, Danne, Thomas, Dutta, Sanjoy, Gabbay, Robert, Garg, Satish, Heverly, Julie, Hirsch, Irl B, Kader, Tina, Kenney, Julia, Kovatchev, Boris, Laffel, Lori, Maahs, David, Mathieu, Chantal, Mauricio, Dídac, Nimri, Revital, Nishimura, Rimei, Scharf, Mauro, Del Prato, Stefano, Renard, Eric, Rosenstock, Julio, Saboo, Banshi, Ueki, Kohjiro, Umpierrez, Guillermo E, Weinzimer, Stuart A, and Phillip, Moshe

Published
2023
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11. Cambridge hybrid closed-loop algorithm in children and adolescents with type 1 diabetes: a multicentre 6-month randomised controlled trial

Author

Hovorka, R, Acerini, C L, Thankamony, A, Allen, J M, Boughton, C K, Dovc, K, Dunger, D B, Ware, J, Musolino, G, Tauschmann, M, Wilinska, M E, Hayes, J F, Hartnell, S, Slegtenhorst, S, Ruan, Y, Haydock, M, Mangat, J, Denvir, L, Kanthagnany, SK, Law, J, Randell, T, Sachdev, P, Saxton, M, Coupe, A, Stafford, S, Ball, A, Keeton, R, Cresswell, R, Crate, L, Cripps, H, Fazackerley, H, Looby, L, Navarra, H, Saddington, C, Smith, V, Verhoeven, V, Bratt, S, Khan, N, Moyes, L, Sandhu, K, West, C, Wadwa, R P, Alonso, G, Forlenza, G, Slover, R, Towers, L, Berget, C, Coakley, A, Escobar, E, Jost, E, Lange, S, Messer, L, Thivener, K, Campbell, F M, Yong, J, Metcalfe, E, Allen, M, Ambler, S, Waheed, S, Exall, J, Tulip, J, Buckingham, B A, Ekhlaspour, L, Maahs, D, Norlander, L, Jacobson, T, Twon, M, Weir, C, Leverenz, B, Keller, J, Davis, N, Kumaran, A, Trevelyan, N, Dewar, H, Price, G, Crouch, G, Ensom, R, Haskell, L, Lueddeke, LM, Mauras, N, Benson, M, Bird, K, Englert, K, Permuy, J, Ponthieux, K, Marrero-Hernandez, J, DiMeglio, L A, Ismail, H, Jolivette, H, Sanchez, J, Woerner, S, Kirchner, M, Mullen, M, Tebbe, M, Besser, R EJ, Basu, S, London, R, Makaya, T, Ryan, F, Megson, C, Bowen-Morris, J, Haest, J, Law, R, Stamford, I, Ghatak, A, Deakin, M, Phelan, K, Thornborough, K, Shakeshaft, J, Weinzimer, S A, Cengiz, E, Sherr, J L, Van Name, M, Weyman, K, Carria, L, Steffen, A, Zgorski, M, Sibayan, J, Beck, R W, Borgman, S, Davis, J, Rusnak, J, Hellman, A, Cheng, P, Kanapka, L, Kollman, C, McCarthy, C, Chalasani, S, Hood, K K, Hanes, S, Viana, J, Lanning, M, Fox, D S, Arreaza-Rubin, G, Eggerman, T, Green, N, Janicek, R, Gabrielson, D, Belle, S H, Castle, J, Green, J, Legault, L, Willi, S M, Wysham, C, Ware, Julia, Boughton, Charlotte K, Allen, Janet M, Wilinska, Malgorzata E, Tauschmann, Martin, Denvir, Louise, Thankamony, Ajay, Campbell, Fiona M, Wadwa, R Paul, Buckingham, Bruce A, Davis, Nikki, DiMeglio, Linda A, Mauras, Nelly, Besser, Rachel E J, Ghatak, Atrayee, Weinzimer, Stuart A, Hood, Korey K, Fox, D Steven, Kanapka, Lauren, Kollman, Craig, Sibayan, Judy, Beck, Roy W, and Hovorka, Roman

Published
2022
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12. TNF-α inhibitors for type 1 diabetes: exploring the path to a pivotal clinical trial.

Author

Bazile, Cassandra, Malik, Magdy M. Abdel, Ackeifi, Courtney, Anderson, Randy L., Beck, Roy W., Donath, Marc Y., Dutta, Sanjoy, Hedrick, Joseph A., Karpen, Stephen R., Kay, Thomas W. H., Marder, Thomas, Marinac, Marjana, McVean, Jennifer, Meyer, Robert, Pettus, Jeremy, Quattrin, Teresa, Verstegen, Ruud H. J., Vieth, Joshua A., and Latres, Esther

Subjects
TYPE 1 diabetes, TUMOR necrosis factors, YOUNG adults, TREND setters, INSULIN pumps
Abstract

Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing b-cells in the pancreas. This destruction leads to chronic hyperglycemia, necessitating lifelong insulin therapy to manage blood glucose levels. Typically diagnosed in children and young adults, T1D can, however, occur at any age. Ongoing research aims to uncover the precise mechanisms underlying T1D and to develop potential interventions. These include efforts to modulate the immune system, regenerate b-cells, and create advanced insulin delivery systems. Emerging therapies, such as closed-loop insulin pumps, stem cell-derived b-cell replacement and disease-modifying therapies (DMTs), offer hope for improving the quality of life for individuals with T1D and potentially moving towards a cure. Currently, there are no disease-modifying therapies approved for stage 3 T1D. Preserving b-cell function in stage 3 T1D is associated with better clinical outcomes, including lower HbA1c and decreased risk of hypoglycemia, neuropathy, and retinopathy. Tumor Necrosis Factor alpha (TNFa) inhibitors have demonstrated efficacy at preserving b-cell function by measurement of C-peptide in two clinical trials in people with stage 3 T1D. However, TNF-a inhibitors have yet to be evaluated in a pivotal trial for T1D. To address the promising clinical findings of TNF-a inhibitors in T1D, Breakthrough T1D convened a panel of key opinion leaders (KOLs) in the field. The workshop aimed to outline an optimal clinical path for moving TNF-a inhibitors to a pivotal clinical trial in T1D. Here, we summarize the evidence for the beneficial use of TNF-a inhibitors in T1D and considerations for strategies collectively identified to advance TNF-a inhibitors beyond phase 2 clinical studies for stage 3 T1D. [ABSTRACT FROM AUTHOR]

Published
2024
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13. A Randomized Comparison of Postprandial Glucose Excursion Using Inhaled Insulin Versus Rapid-Acting Analog Insulin in Adults With Type 1 Diabetes Using Multiple Daily Injections of Insulin or Automated Insulin Delivery.

Author

Hirsch, Irl B., Beck, Roy W., Marak, Martin Chase, Calhoun, Peter, Mottalib, Adham, Salhin, Amna, Manessis, Anastasios, Coviello, Andrea D., Bhargava, Anuj, Thorsell, Ashley, Atakov Castillo, Astrid, Bode, Bruce W., Levister, Camilla, Levy, Carol J., Donahue, Cassandra, Cordero, Christian, Beatson, Christie, Langel, Christine R., Jacobson, Christopher, and Kurek, Corey

Subjects
*INSULIN derivatives, *TYPE 1 diabetes, *BLOOD sugar, *INSULIN therapy, *INSULIN
Abstract

OBJECTIVE: To compare postprandial glucose excursions following a bolus with inhaled technosphere insulin (TI) or subcutaneous rapid-acting analog (RAA) insulin. RESEARCH DESIGN AND METHODS: A meal challenge was completed by 122 adults with type 1 diabetes who were using multiple daily injections (MDI), a nonautomated pump, or automated insulin delivery (AID) and who were randomized to bolus with their usual RAA insulin (n = 61) or TI (n = 61). RESULTS: The primary outcome, the treatment group difference in area under the curve for glucose >180 mg/dL over 2 h, was less with TI versus RAA (adjusted difference −12 mg/dL, 95% CI −22 to −2, P = 0.02). With TI, the glucose excursion was smaller (P = 0.01), peak glucose lower (P = 0.01), and time to peak glucose shorter (P = 0.006). Blood glucose <70 mg/dL occurred in one participant in each group. CONCLUSIONS: Postmeal glucose excursion was smaller with TI than with RAA insulin in a cohort that included both AID and MDI users. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Effect of Impaired Awareness of Hypoglycemia on Glucose Decline During and After Exercise in the T1DEXI Study.

Author

Kamimoto, Jorge L Jo, Li, Zoey, Gal, Robin L, Castle, Jessica R, Doyle, Francis J, Jacobs, Peter G, Martin, Corby K, Beck, Roy W, Calhoun, Peter, Riddell, Michael C, and Rickels, Michael R

Subjects
CONTINUOUS glucose monitoring, TYPE 1 diabetes, GLYCOSYLATED hemoglobin, HYPOGLYCEMIA, INSULIN
Abstract

Context Adults with type 1 diabetes (T1D) face the necessity of balancing the benefits of exercise with the potential hazards of hypoglycemia. Objective This work aimed to assess whether impaired awareness of hypoglycemia (IAH) affects exercise-associated hypoglycemia in adults with T1D. Methods We compared continuous glucose monitoring (CGM)-measured glucose during exercise and for 24 hours following exercise from 95 adults with T1D and IAH (Clarke score ≥4 or ≥1 severe hypoglycemic event within the past year) to 95 "aware" adults (Clarke score ≤2 and no severe hypoglycemic event within the past year) matched on sex, age, insulin delivery modality, and glycated hemoglobin A1c. A total of 4236 exercise sessions, and 1794 exercise days and 839 sedentary days, defined as 24 hours following exercise or a day without exercise, respectively, were available for analysis. Results Participants with IAH exhibited a nonsignificant trend toward greater decline in glucose during exercise compared to "aware" (−21 ± 44 vs −19 ± 43 mg/dL [−1.17 ± 2.44 vs −1.05 ± 2.39 mmol/L], adjusted group difference of −4.2 [95% CI, −8.4 to 0.05] mg/dL [−0.23 95% CI, −.47 to 0.003 mmol/L]; P =.051). Individuals with IAH had a higher proportion of days with hypoglycemic events below 70 mg/dL [3.89 mmol/L] (≥15 minutes <70 mg/dL [<3.89 mmol/L]) both on exercise days (51% vs 43%; P =.006) and sedentary days (48% vs 30%; P =.001). The increased odds of experiencing a hypoglycemic event below 70 mg/dL (<3.89 mmol/L) for individuals with IAH compared to "aware" did not differ significantly between exercise and sedentary days (interaction P =.36). Conclusion Individuals with IAH have a higher underlying risk of hypoglycemia than "aware" individuals. Exercise does not appear to differentially increase risk for hypoglycemia during the activity, or in the subsequent 24 hours for IAH compared to aware individuals with T1D. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Continuous Glucose Monitoring Profiles in Pregnancies With and Without Gestational Diabetes Mellitus.

Author

Durnwald, Celeste, Beck, Roy W., Li, Zoey, Norton, Elizabeth, Bergenstal, Richard M., Johnson, Mary, Dunnigan, Sean, Banfield, Matthew, Krumwiede, Katie, Sibayan, Judy, Calhoun, Peter, and Carlson, Anders L.

Subjects
*CONTINUOUS glucose monitoring, *GESTATIONAL diabetes, *PREGNANT women, *HYPERGLYCEMIA, *GLUCOSE tolerance tests
Abstract

OBJECTIVE: To determine whether continuous glucose monitoring (CGM)-derived glycemic patterns can characterize pregnancies with gestational diabetes mellitus (GDM) as diagnosed by standard oral glucose tolerance test at 24–28 weeks' gestation compared with those without GDM. RESEARCH DESIGN AND METHODS: The analysis includes 768 individuals enrolled from two sites prior to 17 weeks' gestation between June 2020 and December 2021 in a prospective observational study. Participants wore blinded Dexcom G6 CGMs throughout gestation. Main outcome of interest was a diagnosis of GDM by oral glucose tolerance test (OGTT). Glycemic levels in participants with GDM versus without GDM were characterized using CGM-measured glycemic metrics. RESULTS: Participants with GDM (n = 58 [8%]) had higher mean glucose (109 ± 13 vs. 100 ± 8 mg/dL [6.0 ± 0.7 vs. 5.6 ± 0.4 mmol/L], P < 0.001), greater glucose SD (23 ± 4 vs. 19 ± 3 mg/dL [1.3 ± 0.2 vs. 1.1 ± 0.2 mmol/L], P < 0.001), less time in range 63–120 mg/dL (3.5–6.7 mmol/L) (70% ± 17% vs. 84% ± 8%, P < 0.001), greater percent time >120 mg/dL (>6.7 mmol/L) (median 23% vs. 12%, P < 0.001), and greater percent time >140 mg/dL (>7.8 mmol/L) (median 7.4% vs. 2.7%, P < 0.001) than those without GDM throughout gestation prior to OGTT. Median percent time >120 mg/dL (>6.7 mmol/L) and time >140 mg/dL (>7.8 mmol/L) were higher as early as 13–14 weeks of gestation (32% vs. 14%, P < 0.001, and 5.2% vs. 2.0%, P < 0.001, respectively) and persisted during the entire study period prior to OGTT. CONCLUSIONS: Prior to OGTT at 24–34 weeks' gestation, pregnant individuals who develop GDM have higher CGM-measured glucose levels and more hyperglycemia compared with those who do not develop GDM. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Doses of medial rectus muscle recessions for divergence insufficiency-type esotropia

Author

Miller, Aaron M., primary, Holmes, Jonathan M., additional, Wu, Rui, additional, Kraker, Raymond T., additional, Crouch, Eric R., additional, Lee, Katherine A., additional, Del Monte, Monte A., additional, Marsh, Justin D., additional, Kraus, Courtney L., additional, Wallace, David K., additional, Colburn, Jeffrey D., additional, Kemp, Pavlina S., additional, Cotter, Susan A., additional, Beck, Roy W., additional, Alvarez, Gillaine, additional, Austin, Darrell S., additional, Boyle, Nicole M., additional, Chandler, Danielle L., additional, Connelly, Patricia L., additional, Conner, Courtney L., additional, Dean, Trevano W., additional, Donahue, Quayleen, additional, Fimbel, Brooke P., additional, Henderson, Robert J., additional, Hercinovic, Amra, additional, Hoepner, James E., additional, Kaplon, Joseph D., additional, Li, Zhuokai, additional, Melia, B. Michele, additional, Robinson, Julianne L., additional, Shah, Jennifer A., additional, Toro, David O., additional, Jenewein, Erin C., additional, Felius, Joost, additional, Collins, Megan E., additional, Leske, David A., additional, Astle, William F., additional, Birch, Eileen E., additional, Chen, Angela M., additional, Christian, Melanie L., additional, Christiansen, Stephen P., additional, Crouch, Earl R., additional, Donahue, Sean P., additional, Enyedi, Laura B., additional, Erzurum, S. Ayse, additional, Everett, Donald F., additional, Freedman, Sharon F., additional, Good, William V., additional, Lambert, Scott R., additional, London, Richard, additional, Manh, Vivian M., additional, Manny, Ruth E., additional, Morrison, David G., additional, Pineles, Stacy L., additional, Ranaivo, Hantamalala Ralay, additional, Repka, Michael X., additional, Ruark, Scott T., additional, Schweinler, Bonita R., additional, Silver, Jayne L., additional, Summers, Allison I., additional, Verderber, Lisa C., additional, and Weise, Katherine K., additional

Published
2024
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19. Cost-Effectiveness of Closed-Loop Automated Insulin Delivery Using the Cambridge Hybrid Algorithm in Children and Adolescents with Type 1 Diabetes: Results from a Multicenter 6-Month Randomized Trial

Author

Fox, D. Steven, primary, Ware, Julia, additional, Boughton, Charlotte K, additional, Allen, Janet M., additional, Wilinska, Malgorzata E, additional, Tauschmann, Martin, additional, Denvir, Louise, additional, Thankamony, Ajay, additional, Campbell, Fiona, additional, Wadwa, R. Paul, additional, Buckingham, Bruce A., additional, Davis, Nikki, additional, DiMeglio, Linda A., additional, Mauras, Nelly, additional, Besser, Rachel E. J., additional, Ghatak, Atrayee, additional, Weinzimer, Stuart A., additional, Kanapka, Lauren, additional, Kollman, Craig, additional, Sibayan, Judy, additional, Beck, Roy W., additional, Hood, Korey K., additional, and Hovorka, Roman, additional

Published
2024
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24. REPLACE-BG: A Randomized Trial Comparing Continuous Glucose Monitoring With and Without Routine Blood Glucose Monitoring in Adults With Well-Controlled Type 1 Diabetes

Author

Aleppo, Grazia, Ruedy, Katrina J, Riddlesworth, Tonya D, Kruger, Davida F, Peters, Anne L, Hirsch, Irl, Bergenstal, Richard M, Toschi, Elena, Ahmann, Andrew J, Shah, Viral N, Rickels, Michael R, Bode, Bruce W, Philis-Tsimikas, Athena, Pop-Busui, Rodica, Rodriguez, Henry, Eyth, Emily, Bhargava, Anuj, Kollman, Craig, and Beck, Roy W

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Diabetes, Pediatric, Prevention, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Metabolic and endocrine, Adult, Aged, Blood Glucose, Blood Glucose Self-Monitoring, Diabetes Mellitus, Type 1, Female, Glycated Hemoglobin, Humans, Insulin Infusion Systems, Male, Middle Aged, Socioeconomic Factors, Young Adult, REPLACE-BG Study Group, Medical and Health Sciences, Endocrinology & Metabolism, Biomedical and clinical sciences, Health sciences
Abstract

ObjectiveTo determine whether the use of continuous glucose monitoring (CGM) without confirmatory blood glucose monitoring (BGM) measurements is as safe and effective as using CGM adjunctive to BGM in adults with well-controlled type 1 diabetes (T1D).Research design and methodsA randomized noninferiority clinical trial was conducted at 14 sites in the T1D Exchange Clinic Network. Participants were ≥18 years of age (mean 44 ± 14 years), had T1D for ≥1 year (mean duration 24 ± 12 years), used an insulin pump, and had an HbA1c ≤9.0% (≤75 mmol/mL) (mean 7.0 ± 0.7% [53 ± 7.7 mmol/mol]); prestudy, 47% were CGM users. Participants were randomly assigned 2:1 to the CGM-only (n = 149) or CGM+BGM (n = 77) group. The primary outcome was time in range (70-180 mg/dL) over the 26-week trial, with a prespecified noninferiority limit of 7.5%.ResultsCGM use averaged 6.7 ± 0.5 and 6.8 ± 0.4 days/week in the CGM-only and CGM+BGM groups, respectively, over the 26-week trial. BGM tests per day (including the two required daily for CGM calibration) averaged 2.8 ± 0.9 and 5.4 ± 1.4 in the two groups, respectively (P < 0.001). Mean time in 70-180 mg/dL was 63 ± 13% at both baseline and 26 weeks in the CGM-only group and 65 ± 13% and 65 ± 11% in the CGM+BGM group (adjusted difference 0%; one-sided 95% CI -2%). No severe hypoglycemic events occurred in the CGM-only group, and one occurred in the CGM+BGM group.ConclusionsUse of CGM without regular use of confirmatory BGM is as safe and effective as using CGM with BGM in adults with well-controlled T1D at low risk for severe hypoglycemia.

Published
2017

25. Evaluation of Pump Discontinuation and Associated Factors in the T1D Exchange Clinic Registry.

Author

Wong, Jenise C, Boyle, Claire, DiMeglio, Linda A, Mastrandrea, Lucy D, Abel, Kimber-Lee, Cengiz, Eda, Cemeroglu, Pinar A, Aleppo, Grazia, Largay, Joseph F, Foster, Nicole C, Beck, Roy W, Adi, Saleh, and T1D Exchange Clinic Network

Subjects
T1D Exchange Clinic Network, Humans, Diabetes Mellitus, Type 1, Insulin Infusion Systems, Registries, Longitudinal Studies, Patient Compliance, Adolescent, Adult, Child, Child, Preschool, Female, Male, Young Adult, Glycated Hemoglobin, T1D Exchange, adult, children, continuous subcutaneous insulin infusion, discontinuation factors, pump use, Clinical Research, Pediatric Research Initiative, Pediatric, Diabetes, Autoimmune Disease, 6.1 Pharmaceuticals, 7.1 Individual care needs, Evaluation of treatments and therapeutic interventions, Management of diseases and conditions, Nutrition and Dietetics
Abstract

BackgroundThe objectives of this study were to examine factors associated with insulin pump discontinuation among children and adults followed longitudinally for 1 year in the multicenter T1D Exchange clinic registry, and to provide participant-reported reasons for stopping pump therapy.MethodsWe longitudinally followed 8935 participants of all ages using an insulin pump at the time of registry enrollment. Logistic regressions were used to identify demographic and clinical factors associated with pump discontinuation. Pump discontinuation was self-reported by participants on a first annual follow-up survey.ResultsThe overall frequency of pump discontinuation was 3%. Discontinuation was higher in adolescents (4%) and young adults (4%) than in younger children (3%) or older adults (1%). In multivariate analysis of children between 6 and

Published
2017

27. Effect of initiating use of an insulin pump in adults with type 1 diabetes using multiple daily insulin injections and continuous glucose monitoring (DIAMOND): a multicentre, randomised controlled trial

Author

Toschi, Elena, Wolpert, Howard, Atakov-Castillo, Astrid, Markovic, Edvina, Aronoff, Stephen, Brooks, Satanya, Martinez, Gloria, Mendez, Angela, Dunnam, Theresa, Bhargava, Anuj, Fitzgerald, Kathy, Wright, Diana, Khoo, Teck, Theuma, Pierre, Herrold, Tara, Thomsen, Debra, Bergenstal, Richard, McCann, Kathleen, Monk, Arlene, Ashanti, Char, Liljenquist, David, Judge, Heather, Halford, Jean, Kruger, Davida, Levy, Shiri, Bhan, Arti, Cushman, Terra, Dawson, Lameka, Remtema, Heather, Wolf, Fawn, Neifing, James, Murdoch, Jennifer, Staat, Susan, Mayfield, Tamara, Ahmann, Andrew, Klopfenstein, Bethany, Joarder, Farahnaz, Hanavan, Kathy, Castle, Jessica, Aby-Daniel, Diana, Morimoto, Victoria, DeFrang, Donald, Wollam, Bethany, McGill, Janet, Jordan, Olivia, Recklein, Carol, Kipnes, Mark, Haller, Stacie, Ryan, Terri, Bode, Bruce, Boyd, Jennifer, Rastogi, Nitin, Lindmark, Katherine, Biggs, William, Sandoval, Lorena, Eifert, Robin, Cota, Becky, Nguyen, Quang, Martinez, Alejandra, Duran, Cathy, Segel, Scott, Sutton, David, Roura, Miguel, Rosenwasser, Rebecca, McElveen, Jennifer, Knisely, Emily, Johnson, Anne, Odugbesan, A. Ola, Wardell, Karla, Paulus, Carolyn, Wahlen, Jack, Winkfield, Jon, Wahlen, Hilary, Hepworth, Emily, Winkfield, David, Owens, Sue, Leichter, Steven, Evans, Emily, Konigsberg, Sarah, Rahman, Jennifer, Gaudiani, Linda, Woods, Natalie, Cardozo, Jesse, Wheeler, Kate, Kane, Jennifer, Eubanks, Terri, Ruedy, Katrina, Beck, Roy W., Kollman, Craig, Riddlesworth, Tonya, Mouse, Thomas, Price, David, Casal, Eileen, Graham, Claudia, Polonsky, William, Beck, Roy W, Riddlesworth, Tonya D, Ruedy, Katrina J, Ahmann, Andrew J, Bergenstal, Richard M, Bode, Bruce W, Kruger, Davida F, and McGill, Janet B

Published
2017
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30. Corneal Graft Rejection 10 Years After Penetrating Keratoplasty in the Cornea Donor Study

Author

Dunn, Steven P, Gal, Robin L, Kollman, Craig, Raghinaru, Dan, Dontchev, Mariya, Blanton, Christopher L, Holland, Edward J, Lass, Jonathan H, Kenyon, Kenneth R, Mannis, Mark J, Mian, Shahzad I, Rapuano, Christopher J, Stark, Walter J, and Beck, Roy W

Subjects
Organ Transplantation, Eye Disease and Disorders of Vision, Neurodegenerative, Clinical Research, Transplantation, Rare Diseases, 6.4 Surgery, Evaluation of treatments and therapeutic interventions, Eye, Aged, Allografts, Corneal Edema, Follow-Up Studies, Fuchs' Endothelial Dystrophy, Graft Rejection, Graft Survival, Humans, Incidence, Keratoplasty, Penetrating, Middle Aged, Postoperative Complications, Risk Factors, Tissue Donors, Transplant Recipients, corneal graft rejection, penetrating keratoplasty, corneal graft failure, Writing Committee for the Cornea Donor Study Research Group, Clinical Sciences, Opthalmology and Optometry, Ophthalmology & Optometry
Abstract

PurposeThe aim of this study was to assess the effect of donor and recipient factors on corneal allograft rejection and evaluate whether a rejection event was associated with graft failure.MethodsOne thousand ninety subjects undergoing penetrating keratoplasty for a moderate risk condition (principally Fuchs dystrophy or pseudophakic corneal edema) were followed for up to 12 years. Associations of baseline recipient and donor factors with the occurrence of a rejection event were assessed in univariate and multivariate proportional hazards models.ResultsAmong 651 eyes with a surviving graft at 5 years, the 10-year graft failure (±99% confidence interval) rates were 12% ± 4% among eyes with no rejection events in the first 5 years, 17% ± 12% in eyes with at least 1 probable, but no definite rejection event, and 22% ± 20% in eyes with at least 1 definite rejection event. The only baseline factor significantly associated with a higher risk of definite graft rejection was a preoperative history of glaucoma, particularly when previous glaucoma surgery had been performed and glaucoma medications were being used at the time of transplant (10-year incidence 35% ± 23% compared with 14% ± 4% in eyes with no history of glaucoma/intraocular pressure treatment, P = 0.008).ConclusionsPatients who experienced a definite rejection event frequently developed graft failure raising important questions as to how we might change acute and long-term corneal graft management. Multivariate analysis indicated that previous use of glaucoma medications and glaucoma filtering surgery was a significant risk factor related to a definite rejection event.

Published
2014

31. Real-Time Continuous Glucose Monitoring Among Participants in the T1D Exchange Clinic Registry

Author

Wong, Jenise C, Foster, Nicole C, Maahs, David M, Raghinaru, Dan, Bergenstal, Richard M, Ahmann, Andrew J, Peters, Anne L, Bode, Bruce W, Aleppo, Grazia, Hirsch, Irl B, Kleis, Lora, Chase, H Peter, DuBose, Stephanie N, Miller, Kellee M, Beck, Roy W, and Adi, Saleh

Subjects
Clinical Research, Diabetes, Prevention, Pediatric, Bioengineering, Autoimmune Disease, Metabolic and endocrine, Adolescent, Adult, Blood Glucose, Blood Glucose Self-Monitoring, Child, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Diabetic Ketoacidosis, Female, Glycated Hemoglobin, Humans, Hypoglycemia, Incidence, Insulin, Insulin Infusion Systems, Male, Monitoring, Ambulatory, Patient Education as Topic, Registries, Retrospective Studies, Risk Factors, Young Adult, T1D Exchange Clinic Network
Abstract

ObjectiveTo assess the frequency of continuous glucose monitoring (CGM) device use, factors associated with its use, and the relationship of CGM with diabetes outcomes (HbA1c, severe hypoglycemia [SH], and diabetic ketoacidosis [DKA]).Research design and methodsSurvey questions related to CGM device use 1 year after enrollment in the T1D Exchange clinic registry were completed by 17,317 participants. Participants were defined as CGM users if they indicated using real-time CGM during the prior 30 days.ResultsNine percent of participants used CGM (6% of children

Published
2014

32. A contrast between children and adolescents with excellent and poor control: the T1D exchange clinic registry experience

Author

Campbell, Meredith S, Schatz, Desmond A, Chen, Vincent, Wong, Jenise C, Steck, Andrea, Tamborlane, William V, Smith, Jennifer, Beck, Roy W, Cengiz, Eda, Laffel, Lori M, Miller, Kellee M, Haller, Michael J, and Network, for the T1D Exchange Clinic

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Autoimmune Disease, Pediatric Research Initiative, Prevention, Pediatric, Diabetes, Management of diseases and conditions, 7.1 Individual care needs, Metabolic and endocrine, Adolescent, Ambulatory Care Facilities, Blood Glucose, Child, Diabetes Mellitus, Type 1, Diabetic Ketoacidosis, Female, Glycated Hemoglobin, Humans, Hypoglycemia, Male, Registries, Self Care, Socioeconomic Factors, United States, pediatric, blood glucose self-monitoring, type 1 diabetes mellitus, diabetes mellitus, insulin, T1D Exchange Clinic Network, Paediatrics and Reproductive Medicine, Endocrinology & Metabolism, Clinical sciences, Paediatrics
Abstract

ObjectivesOptimizing glycemic control in pediatric type 1 diabetes (T1D) is essential to minimizing long-term risk of complications. We used the T1D Exchange database from 58 US diabetes clinics to identify differences in diabetes management characteristics among children categorized as having excellent vs. poor glycemic control.MethodsAmong registry participants 6-17 yr old with diabetes duration ≥ 2 yr, those with excellent control [(A1c

Published
2014

33. A Comparison of Continuous Glucose Monitoring-Measured Time-in-Range 70–180 mg/dL Versus Time-in-Tight-Range 70–140 mg/dL.

Author

Beck, Roy W., Raghinaru, Dan, Calhoun, Peter, and Bergenstal, Richard M.

Subjects
*CONTINUOUS glucose monitoring, *TYPE 1 diabetes, *TYPE 2 diabetes, *GLUCOSE
Abstract

Objective: To evaluate the relationship between continuous glucose monitoring (CGM)-measured time-in-range 70–180 mg/dL (TIR) and time-in-tight-range 70–140 mg/dL (TITR). Methods: TIR and TITR were calculated from CGM data collected using blinded or unblinded Dexcom sensors from 9 studies with 912 participants with type 1 diabetes (T1D) and 2 studies with 184 participants with type 2 diabetes (T2D). The TIR-TITR relationship was assessed overall and stratified by coefficient of variation (CV) and by time below range <70 mg/dL (TBR). Results: The correlation between TIR and TITR was 0.94. TITR was higher for a given TIR for T2D compared with T1D. However, after adjusting for the differences in CV or TBR, both of which were higher with T1D than T2D, the differences were minimized. The TIR-TITR relationship was nonlinear, with a higher ratio of TITR:TIR observed as TIR increased ranging from 0.42 when TIR was 20% to 0.66 when TIR was 80%. Similarly, as TITR increased, the ratio of TIR:TITR decreased, varying from 2.6 with TITR of 10% to 1.3 for TITR of 70%. The TIR-TITR relationship varied according to CV and TBR, such that the higher the CV or higher the amount of TBR the greater was TITR for a given TIR. Conclusions: TIR and TITR are highly correlated, although the relationship is nonlinear. With knowledge of TIR, TITR can be estimated with reasonable precision. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Comprehensive Telehealth Model to Support Diabetes Self-Management

Author

Aleppo, Grazia, primary, Gal, Robin L., additional, Raghinaru, Dan, additional, Kruger, Davida, additional, Beck, Roy W., additional, Bergenstal, Richard M., additional, Cushman, Terra, additional, Hood, Korey K., additional, Johnson, Mary L., additional, McArthur, Teresa, additional, Bradshaw, Amy, additional, Olson, Beth A., additional, Oser, Sean M., additional, Oser, Tamara K., additional, Kollman, Craig, additional, and Weinstock, Ruth S., additional

Published
2023
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36. Home OCT Imaging for Newly Diagnosed Neovascular Age-Related Macular Degeneration

Author

Blinder, Kevin J., primary, Calhoun, Claire, additional, Maguire, Maureen G., additional, Glassman, Adam R., additional, Mein, Calvin E., additional, Baskin, Darrell E., additional, Vieyra, Gabriela, additional, Jampol, Lee M., additional, Chica, Moises A., additional, Sun, Jennifer K., additional, Martin, Daniel F., additional, Beck, Roy W., additional, Baptista, Alyssa, additional, Beaulieu, Wesley T., additional, Calhoun, Claire T., additional, Constantine, Sharon R., additional, Dale, Brian B., additional, Dupre, Simone S., additional, Franklin, Crystal A., additional, Galusic, Sandra, additional, Huggins, Meagan, additional, Hunter, Brenda L., additional, Johnson, Paula A., additional, Josic, Kristin, additional, Kelly, Brittany, additional, Liu, Danni, additional, Meadows, Britney, additional, Melia, Michele, additional, Preston, Carin M., additional, Stockdale, Cynthia R., additional, Zokruah, Alice, additional, Bhargava, Sangeeta, additional, Barkmeier, Andrew J., additional, Baskin, Darrell, additional, Blodi, Barbra, additional, Chew, Emily, additional, Ferris, Frederick L., additional, Jaffe, Glenn J., additional, Jhaveri, Chirag D., additional, MacCumber, Mathew, additional, Maturi, Raj K., additional, Solomon, Sharon D., additional, Antoszyk, Andrew N., additional, Lujan, Brandon, additional, Slahi-Had, Hani, additional, Lane, Richard Gary, additional, Adams, Lydia, additional, Rivera, Rachel R., additional, Nakoski, Brenda, additional, Weeks, Rhonda F., additional, Braverman, Allan L., additional, McDonald-Mueller, Lauren, additional, Stuart, Maria A., additional, Pulliam, Brook G., additional, Boyd, Lynda K., additional, Wehmeier, Jarrod, additional, Schremp, Steve A., additional, Googe, Joseph M., additional, Oliver, Kristina, additional, Walsh, Justin, additional, Asher, Julie, additional, Milstead, Katie, additional, Wheeler, Jeff, additional, and Griffone, Hodge A., additional

Published
2023
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37. Automated Insulin Delivery with Remote Real-Time Continuous Glucose Monitoring for Hospitalized Patients with Diabetes: A Multicenter, Single-Arm, Feasibility Trial

Author

Davis, Georgia M., primary, Hughes, Michael S., additional, Brown, Sue A., additional, Sibayan, Judy, additional, Perez-Guzman, M. Citlalli, additional, Stumpf, Meaghan, additional, Thompson, Zachary, additional, Basina, Marina, additional, Patel, Ronak M., additional, Hester, Joi, additional, Abraham, Amalia, additional, Ly, Trang T., additional, Chaney, Cherie, additional, Tan, Marilyn, additional, Hsu, Liana, additional, Kollman, Craig, additional, Beck, Roy W., additional, Lal, Rayhan, additional, Buckingham, Bruce, additional, and Pasquel, Francisco J., additional

Published
2023
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38. Beneficial Effects of Control-IQ Automated Insulin Delivery in Basal-Bolus and Basal-Only Insulin Users With Type 2 Diabetes

Author

Levy, Carol J., primary, Raghinaru, Dan, additional, Kudva, Yogish C., additional, Pandit, Keta, additional, Blevins, Thomas, additional, Casaubon, Luis, additional, Desjardins, Donna, additional, Levister, Camilla M., additional, O’Malley, Grenye, additional, Reid, Corey, additional, Lum, John, additional, Kollman, Craig, additional, and Beck, Roy W., additional

Published
2023
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39. Donor Age and Factors Related to Endothelial Cell Loss 10 Years after Penetrating Keratoplasty Specular Microscopy Ancillary Study

Author

Group, Writing Committee for the Cornea Donor Study Research, Lass, Jonathan H, Benetz, Beth Ann, Gal, Robin L, Kollman, Craig, Raghinaru, Dan, Dontchev, Mariya, Mannis, Mark J, Holland, Edward J, Chow, Christopher, McCoy, Kristen, Price, Francis W, Sugar, Alan, Verdier, David D, and Beck, Roy W

Subjects
Transplantation, Clinical Trials and Supportive Activities, Eye Disease and Disorders of Vision, Clinical Research, Eye, Adolescent, Adult, Aged, Aging, Cell Count, Child, Corneal Edema, Corneal Endothelial Cell Loss, Double-Blind Method, Endothelium, Corneal, Eye Banks, Female, Fuchs' Endothelial Dystrophy, Graft Survival, Humans, Keratoplasty, Penetrating, Male, Middle Aged, Postoperative Complications, Prospective Studies, Risk Factors, Time Factors, Tissue Donors, Young Adult, Writing Committee for the Cornea Donor Study Research Group, Clinical Sciences, Opthalmology and Optometry, Public Health and Health Services, Ophthalmology & Optometry
Abstract

ObjectiveTo examine the effect of donor age and other perioperative factors on long-term endothelial cell loss after penetrating keratoplasty (PKP).DesignMulticenter, prospective, double-masked clinical trial.ParticipantsWe included 176 participants from the Cornea Donor Study cohort who had not experienced graft failure ≥ 10 years after PKP for a moderate risk condition (principally Fuchs' dystrophy or pseudophakic/aphakic corneal edema).MethodsCorneas from donors 12 to 75 years old were assigned to participants using a randomized approach, without respect to recipient factors. Surgery and postoperative care were performed according to the surgeons' usual routines. Images of the central endothelium were obtained preoperatively and at intervals for 10 years postoperatively. Images were analyzed by a central image analysis reading center to determine endothelial cell density (ECD).Main outcome measuresEndothelial cell density at 10 years.ResultsAmong study participants with a clear graft at 10 years, the 125 who received a cornea from a donor 12 to 65 years old experienced a median cell loss of 76%, resulting in a 10-year median ECD of 628 cells/mm(2) (interquartile range [IQR], 522-850 cells/mm(2)), whereas the 51 who received a cornea from a donor 66 to 75 years old experienced a cell loss of 79%, resulting in a median 10-year ECD of 550 cells/mm(2) (IQR, 483-694 cells/mm(2); P adjusted for baseline ECD = 0.03). In addition to younger donor age, higher ECD values were significantly associated with higher baseline ECD (P1000 cells/mm(2).ConclusionsSubstantial cell loss occurs in eyes with a clear graft 10 years after PKP, with the rate of cell loss being slightly greater with older donor age. Greater preoperative ECD and larger donor tissue size are associated with higher ECD at 10 years.

Published
2013

40. The Effect of Donor Age on Penetrating Keratoplasty for Endothelial Disease Graft Survival after 10 Years in the Cornea Donor Study

Author

Group, Writing Committee for the Cornea Donor Study Research, Mannis, Mark J, Holland, Edward J, Gal, Robin L, Dontchev, Mariya, Kollman, Craig, Raghinaru, Dan, Dunn, Steven P, Schultze, Robert L, Verdier, David D, Lass, Jonathan H, Raber, Irving M, Sugar, Joel, Gorovoy, Mark S, Sugar, Alan, Stulting, R Doyle, Montoya, Monty M, Penta, Jeffrey G, Benetz, Beth Ann, and Beck, Roy W

Subjects
Eye Disease and Disorders of Vision, Clinical Trials and Supportive Activities, Transplantation, Clinical Research, Eye, Adolescent, Adult, Age Factors, Aged, Aging, Child, Corneal Edema, Double-Blind Method, Eye Banks, Female, Follow-Up Studies, Fuchs' Endothelial Dystrophy, Graft Survival, Humans, Keratoplasty, Penetrating, Male, Middle Aged, Prospective Studies, Registries, Tissue Donors, Young Adult, Writing Committee for the Cornea Donor Study Research Group, Clinical Sciences, Opthalmology and Optometry, Public Health and Health Services, Ophthalmology & Optometry
Abstract

ObjectiveTo determine whether the 10-year success rate of penetrating keratoplasty for corneal endothelial disorders is associated with donor age.DesignMulticenter, prospective, double-masked clinical trial.ParticipantsA total of 1090 participants undergoing penetrating keratoplasty at 80 sites for Fuchs' dystrophy (62%), pseudophakic/aphakic corneal edema (34%), or another corneal endothelial disorder (4%) and followed for up to 12 years.MethodsForty-three eye banks provided corneas from donors aged 12 to 75 years, using a randomized approach to assign donor corneas to study participants without respect to recipient factors. Surgery and postoperative care were performed according to the surgeons' usual routines.Main outcome measuresGraft failure defined as a regraft or, in the absence of a regraft, a cloudy cornea that was sufficiently opaque to compromise vision for 3 consecutive months.ResultsIn the primary analysis, the 10-year success rate was 77% for 707 corneas from donors aged 12 to 65 years compared with 71% for 383 donors aged 66 to 75 years (difference, +6%; 95% confidence interval, -1 to +12; P = 0.11). When analyzed as a continuous variable, higher donor age was associated with lower graft success beyond the first 5 years (P

Published
2013

41. Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice

Author

Phillip, Moshe, Nimri, Revital, Bergenstal, Richard M, Barnard-Kelly, Katharine, Danne, Thomas, Hovorka, Roman, Kovatchev, Boris P, Messer, Laurel H, Parkin, Christopher G, Ambler-Osborn, Louise, Amiel, Stephanie A, Bally, Lia, Beck, Roy W, Biester, Sarah, Biester, Torben, Blanchette, Julia E, Bosi, Emanuele, Boughton, Charlotte K, Breton, Marc D, Brown, Sue A, Buckingham, Bruce A, Cai, Albert, Carlson, Anders L, Castle, Jessica R, Choudhary, Pratik, Close, Kelly L, Cobelli, Claudio, Criego, Amy B, Davis, Elizabeth, de Beaufort, Carine, de Bock, Martin I, DeSalvo, Daniel J, DeVries, J Hans, Dovc, Klemen, Doyle, Francis J, Ekhlaspour, Laya, Shvalb, Naama Fisch, Forlenza, Gregory P, Gallen, Geraldine, Garg, Satish K, Gershenoff, Dana C, Gonder-Frederick, Linda A, Haidar, Ahmad, Hartnell, Sara, Heinemann, Lutz, Heller, Simon, Hirsch, Irl B, Hood, Korey K, Isaacs, Diana, Klonoff, David C, Kordonouri, Olga, Kowalski, Aaron, Laffel, Lori, Lawton, Julia, Lal, Rayhan A, Leelarathna, Lalantha, Maahs, David M, Murphy, Helen R, Nørgaard, Kirsten, O'Neal, David, Oser, Sean, Oser, Tamara, Renard, Eric, Riddell, Michael C, Rodbard, David, Russell, Steven J, Schatz, Desmond A, Shah, Viral N, Sherr, Jennifer L, Simonson, Gregg D, Wadwa, R Paul, Ward, Candice, Weinzimer, Stuart A, Wilmot, Emma G, Battelino, Tadej, General Internal Medicine, APH - Health Behaviors & Chronic Diseases, and AGEM - Amsterdam Gastroenterology Endocrinology Metabolism

Subjects
closed-loop, Endocrinology, consensus recommendations, automated insulin delivery, type 1 diabetes, Endocrinology, Diabetes and Metabolism, 610 Medicine & health, 610 Medizin und Gesundheit
Abstract

The significant and growing global prevalence of diabetes continues to challenge people with diabetes (PwD), healthcare providers, and payers. While maintaining near-normal glucose levels has been shown to prevent or delay the progression of the long-term complications of diabetes, a significant proportion of PwD are not attaining their glycemic goals. During the past 6 years, we have seen tremendous advances in automated insulin delivery (AID) technologies. Numerous randomized controlled trials and real-world studies have shown that the use of AID systems is safe and effective in helping PwD achieve their long-term glycemic goals while reducing hypoglycemia risk. Thus, AID systems have recently become an integral part of diabetes management. However, recommendations for using AID systems in clinical settings have been lacking. Such guided recommendations are critical for AID success and acceptance. All clinicians working with PwD need to become familiar with the available systems in order to eliminate disparities in diabetes quality of care. This report provides much-needed guidance for clinicians who are interested in utilizing AIDs and presents a comprehensive listing of the evidence payers should consider when determining eligibility criteria for AID insurance coverage.

Published
2023

42. Severe hypoglycemia and diabetic ketoacidosis among youth with type 1 diabetes in the T1D Exchange clinic registry

Author

Cengiz, Eda, Xing, Dongyuan, Wong, Jenise C, Wolfsdorf, Joseph I, Haymond, Morey W, Rewers, Arleta, Shanmugham, Satya, Tamborlane, William V, Willi, Steven M, Seiple, Diane L, Miller, Kellee M, DuBose, Stephanie N, Beck, Roy W, and Network, for the T1D Exchange Clinic

Subjects
Prevention, Pediatric Research Initiative, Autoimmune Disease, Clinical Research, Pediatric, Diabetes, Metabolic and endocrine, Adolescent, Adolescent Development, Adult, Child, Child Development, Child, Preschool, Cohort Studies, Diabetes Mellitus, Type 1, Diabetic Ketoacidosis, Glycated Hemoglobin, Humans, Hyperglycemia, Hypoglycemia, Hypoglycemic Agents, Logistic Models, Registries, Risk, Severity of Illness Index, United States, Young Adult, childhood type 1, diabetic ketoacidosis, hypoglycemia, pediatric diabetes, type 1, T1D Exchange Clinic Network, Paediatrics and Reproductive Medicine, Endocrinology & Metabolism
Abstract

ObjectiveSevere hypoglycemia (SH) and diabetic ketoacidosis (DKA) are common serious acute complications of type 1 diabetes (T1D). The aim of this study was to determine the frequency of SH and DKA and identify factors related to their occurrence in the T1D Exchange pediatric and young adult cohort.Research design and methodsThe analysis included 13 487 participants in the T1D Exchange clinic registry aged 2 to

Published
2013

43. Comparing autoantibody status

Author

Gerard‐Gonzalez, Andrea, Gitelman, Stephen E, Cheng, Peiyao, Dubose, Stephanie N, Miller, Kellee M, Olson, Beth A, Redondo, Maria J, Steck, Andrea K, and Beck, Roy W

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Autoimmune Disease, Pediatric, Diabetes, Metabolic and endocrine, Autoantibodies, Body Composition, Body Mass Index, Child, Child, Preschool, Diabetes Mellitus, Type 1, Female, Humans, Male, Registries, autoantibodies, autoantibody, childhood type 1 diabetes, pediatric diabetes, Public Health and Health Services, Clinical sciences, Epidemiology
Abstract

ObjectiveTo compare characteristics of autoantibody (aAb)-positive and -negative cases of type 1 diabetes (T1D)

Published
2013

44. Psychosocial Impact of the Insulin-Only iLet Bionic Pancreas for Adults, Youth, and Caregivers of Youth with Type 1 Diabetes

Author

Weissberg-Benchell, Jill, primary, Vesco, Anthony T., additional, Shapiro, Jenna, additional, Calhoun, Peter, additional, Damiano, Edward, additional, Russell, Steven J, additional, Li, Zoey, additional, El-Khatib, Firas, additional, Ruedy, Katrina J., additional, Balliro, Courtney, additional, and Beck, Roy W., additional

Published
2023
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46. Beneficial Effects of Control-IQ Automated Insulin Delivery in Basal-Bolus and Basal-Only Insulin Users With Type 2 Diabetes.

Author

Levy, Carol J., Raghinaru, Dan, Kudva, Yogish C., Pandit, Keta, Blevins, Thomas, Casaubon, Luis, Desjardins, Donna, Levister, Camilla M., O’Malley, Grenye, Reid, Corey, Lum, John, Kollman, Craig, and Beck, Roy W.

Subjects
RESEARCH, CLINICAL trials, CONFIDENCE intervals, HYPOGLYCEMIC agents, TYPE 2 diabetes, INSULIN, TREATMENT effectiveness, COMPARATIVE studies, T-test (Statistics), INSULIN pumps, RESEARCH funding, DESCRIPTIVE statistics, QUESTIONNAIRES, DATA analysis software, PATIENT safety, LONGITUDINAL method
Abstract

The t:slim X2 insulin pump with Control-IQ technology (Control-IQ) advanced hybrid closed-loop automated insulin delivery system was evaluated in this prospective single-arm trial. Thirty adults with type 2 diabetes using the Control-IQ system showed substantial glycemic improvement with no increase in hypoglycemia. Mean time in range (70–180 mg/dL) improved 15%, representing an increase of 3.6 hours/day, and mean glucose decreased by 22 mg/dL. [ABSTRACT FROM AUTHOR]

Published
2024
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48. Trial of Hybrid Closed-Loop Control in Young Children with Type 1 Diabetes

Author

Wadwa, R. Paul, primary, Reed, Zachariah W., additional, Buckingham, Bruce A., additional, DeBoer, Mark D., additional, Ekhlaspour, Laya, additional, Forlenza, Gregory P., additional, Schoelwer, Melissa, additional, Lum, John, additional, Kollman, Craig, additional, Beck, Roy W., additional, and Breton, Marc D., additional

Published
2023
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50. The Type 1 Diabetes and EXercise Initiative (T1DEXI): Examining the acute glycemic effects of different types of structured exercise sessions in type 1 diabetes in a real-world setting

Author

Riddell, Michael C., primary, Li, Zoey, primary, Gal, Robin L., primary, Calhoun, Peter, primary, Jacobs, Peter G., primary, Clements, Mark A., primary, Martin, Corby K., primary, III, Francis J. Doyle,, primary, Patton, Susana R., primary, Castle, Jessica R., primary, Gillingham, Melanie B., primary, Beck, Roy W., primary, and Rickels, Michael R., primary

Published
2023
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