176 results on '"Becher JG"'
Search Results
2. Chirurgie bij heup (sub)luxaties bij kinderen met CP: Van richtlijn naar landelijke registratie
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Nederhand, Marc, Boldingh, Eric, van der Sluijs, J.A., Buizer, AI, Becher, JG, Rehabilitation medicine, and AMS - Rehabilitation & Development
- Published
- 2021
3. Selective dorsal rhizotomy as treatment in cerebral palsy
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Martens, Brian H M, van Schie, PEM, van Ouwerkerk, WJR, Becher, JG, Vermeulen, R. Jeroen, Buizer, AI, Rehabilitation medicine, Amsterdam Movement Sciences - Restoration and Development, and Neurosurgery
- Published
- 2018
4. Van revisie tot implementatie: Richtlijn Diagnostiek en behandeling spastische cerebrale parese bij kinderen
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Buizer, AI, Voorman, J.M., Hilberink, S.R., Ketelaar, Marjolijn, Becher, JG, Rehabilitation medicine, and Amsterdam Movement Sciences - Restoration and Development
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- 2018
5. Behandeling van spasticiteit bij kinderen door Selectieve Dorsale Rhizotomie: indicaties en resultaten
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Becher, JG, Bolster, EAM, van Ouwerkerk, WJR, Strijers, RLM, van Schie, PEM, Vermeulen, R. Jeroen, van de Pol, LA, Stadhouder, A, and Buizer, AI
- Published
- 2018
6. Outcome of medial hamstring lengthening in children with spastic paresis: A biomechanical and morphological observational study
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Martinuzzi, A, Haberfehlner, H, Jaspers, RT, Rutz, E, Harlaar, J, van der Sluijs, JA, Witbreuk, MM, van Hutten, K, Romkes, J, Freslier, M, Brunner, R, Becher, JG, Maas, H, Buizer, AI, Martinuzzi, A, Haberfehlner, H, Jaspers, RT, Rutz, E, Harlaar, J, van der Sluijs, JA, Witbreuk, MM, van Hutten, K, Romkes, J, Freslier, M, Brunner, R, Becher, JG, Maas, H, and Buizer, AI
- Abstract
To improve gait in children with spastic paresis due to cerebral palsy or hereditary spastic paresis, the semitendinosus muscle is frequently lengthened amongst other medial hamstring muscles by orthopaedic surgery. Side effects on gait due to weakening of the hamstring muscles and overcorrections have been reported. How these side effects relate to semitendinosus morphology is unknown. This study assessed the effects of bilateral medial hamstring lengthening as part of single-event multilevel surgery (SEMLS) on (1) knee joint mechanics (2) semitendinosus muscle morphology and (3) gait kinematics. All variables were assessed for the right side only. Six children with spastic paresis selected for surgery to counteract limited knee range of motion were measured before and about a year after surgery. After surgery, in most subjects popliteal angle decreased and knee moment-angle curves were shifted towards a more extended knee joint, semitendinosus muscle belly length was approximately 30% decreased, while at all assessed knee angles tendon length was increased by about 80%. In the majority of children muscle volume of the semitendinosus muscle decreased substantially suggesting a reduction of physiological cross-sectional area. Gait kinematics showed more knee extension during stance (mean change ± standard deviation: 34±13°), but also increased pelvic anterior tilt (mean change ± standard deviation: 23±5°). In most subjects, surgical lengthening of semitendinosus tendon contributed to more extended knee joint angle during static measurements as well as during gait, whereas extensibility of semitendinosus muscle belly was decreased. Post-surgical treatment to maintain muscle belly length and physiological cross-sectional area may improve treatment outcome of medial hamstring lengthening.
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- 2018
7. Somatisch Onvoldoende Verklaarde Lichamelijke Klachten (Solk)
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Beusekom, Babette, Hadders-Algra, M, Maathuis, K, Pangalila, RF, Becher, JG, de Moor, J, and Child and Adolescent Psychiatry / Psychology
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- 2015
8. Knee Moment-Angle Characteristics and Semitendinosus Muscle Morphology in Children with Spastic Paresis Selected for Medial Hamstring Lengthening
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Martinuzzi, A, Haberfehlner, H, Jaspers, RT, Rutz, E, Becher, JG, Harlaar, J, van der Sluijs, JA, Witbreuk, MM, Romkes, J, Freslier, M, Brunner, R, Maas, H, Buizer, AI, Martinuzzi, A, Haberfehlner, H, Jaspers, RT, Rutz, E, Becher, JG, Harlaar, J, van der Sluijs, JA, Witbreuk, MM, Romkes, J, Freslier, M, Brunner, R, Maas, H, and Buizer, AI
- Abstract
To increase knee range of motion and improve gait in children with spastic paresis (SP), the semitendinosus muscle (ST) amongst other hamstring muscles is frequently lengthened by surgery, but with variable success. Little is known about how the pre-surgical mechanical and morphological characteristics of ST muscle differ between children with SP and typically developing children (TD). The aims of this study were to assess (1) how knee moment-angle characteristics and ST morphology in children with SP selected for medial hamstring lengthening differ from TD children, as well as (2) how knee moment-angle characteristics and ST morphology are related. In nine SP and nine TD children, passive knee moment-angle characteristics and morphology of ST (i.e. fascicle length, muscle belly length, tendon length, physiological cross-sectional area, and volume) were assessed by hand-held dynamometry and freehand 3D ultrasound, respectively. At net knee flexion moments above 0.5 Nm, more flexed knee angles were found for SP compared to TD children. The measured knee angle range between 0 and 4 Nm was 30% smaller in children with SP. Muscle volume, physiological cross-sectional area, and fascicle length normalized to femur length were smaller in SP compared to TD children (62%, 48%, and 18%, respectively). Sixty percent of the variation in knee angles at 4 Nm net knee moment was explained by ST fascicle length. Altered knee moment-angle characteristics indicate an increased ST stiffness in SP children. Morphological observations indicate that in SP children planned for medial hamstring lengthening, the longitudinal and cross-sectional growth of ST muscle fibers is reduced. The reduced fascicle length can partly explain the increased ST stiffness and, hence, a more flexed knee joint in these SP children.
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- 2016
9. Cerebral palsy
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Graham, HK, Rosenbaum, P, Paneth, N, Dan, B, Lin, J-P, Damiano, DL, Becher, JG, Gaebler-Spira, D, Colver, A, Reddihough, D, Crompton, KE, Lieber, RL, Graham, HK, Rosenbaum, P, Paneth, N, Dan, B, Lin, J-P, Damiano, DL, Becher, JG, Gaebler-Spira, D, Colver, A, Reddihough, D, Crompton, KE, and Lieber, RL
- Abstract
Cerebral palsy is the most common cause of childhood-onset, lifelong physical disability in most countries, affecting about 1 in 500 neonates with an estimated prevalence of 17 million people worldwide. Cerebral palsy is not a disease entity in the traditional sense but a clinical description of children who share features of a non-progressive brain injury or lesion acquired during the antenatal, perinatal or early postnatal period. The clinical manifestations of cerebral palsy vary greatly in the type of movement disorder, the degree of functional ability and limitation and the affected parts of the body. There is currently no cure, but progress is being made in both the prevention and the amelioration of the brain injury. For example, administration of magnesium sulfate during premature labour and cooling of high-risk infants can reduce the rate and severity of cerebral palsy. Although the disorder affects individuals throughout their lifetime, most cerebral palsy research efforts and management strategies currently focus on the needs of children. Clinical management of children with cerebral palsy is directed towards maximizing function and participation in activities and minimizing the effects of the factors that can make the condition worse, such as epilepsy, feeding challenges, hip dislocation and scoliosis. These management strategies include enhancing neurological function during early development; managing medical co-morbidities, weakness and hypertonia; using rehabilitation technologies to enhance motor function; and preventing secondary musculoskeletal problems. Meeting the needs of people with cerebral palsy in resource-poor settings is particularly challenging.
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- 2016
10. A randomized controlled trial studying efficacy and tolerance of a knee-ankle-foot orthosis used to prevent equinus in children with spastic cerebral palsy
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Maas, JC, primary, Dallmeijer, AJ, additional, Huijing, PA, additional, Brunstrom-Hernandez, JE, additional, van Kampen, PJ, additional, Bolster, EAM, additional, Dunn, C, additional, Herndon, K, additional, Jaspers, RT, additional, and Becher, JG, additional
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- 2014
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11. Dynamic spasticity of plantar flexor muscles in cerebral palsy gait
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van der Krogt, MM, primary, Doorenbosch, CAM, additional, Becher, JG, additional, and Harlaar, J, additional
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- 2010
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12. ‘Satisfaction with intrathecal baclofen treatment in paediatric patients with progressive neurological disease’
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Bonouvrié, LA, primary, van Schie, PEM, additional, Becher, JG, additional, van Ouwerkerk, WJR, additional, and Vermeulen, RJ, additional
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- 2008
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13. Teleconsultation using movement analysis can affect patient treatment
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Bloo, JKC, primary, Kleissen, RFM, additional, Nene, AV, additional, Becher, JG, additional, Harlaar, J, additional, and Zilvold, G, additional
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- 1999
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14. Synergy of EMG patterns in gait as an objective measure of muscle selectivity in children with spastic cerebral palsy.
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Zwaan E, Becher JG, and Harlaar J
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- 2012
15. Effectiveness of functional progressive resistance exercise training on walking ability in children with cerebral palsy: a randomized controlled trial.
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Scholtes VA, Becher JG, Janssen-Potten YJ, Dekkers H, Smallenbroek L, and Dallmeijer AJ
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- 2012
16. Physical activity in young children with cerebral palsy.
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Zwier JN, van Schie PEM, Becher JG, Smits D, Gorter JW, and Dallmeijer AJ
- Abstract
Purpose. The aim of this study was to describe the physical activity levels of 5- and 7-year-old children with cerebral palsy (CP, n = 97), to compare their physical activity levels with those of typically developing peers (TD, n = 57) and the Dutch recommendation for physical activity, and to investigate the associated factors. Method. The level of physical activity (hours spent on sports and physical activity per week) and contextual factors were assessed with standardised questionnaires. Results. Mean duration of self-reported physical activity for children with CP was 3.4 (± 1.9) h/week, which was significantly less than the 5.8 (± 2.3) h/week for TD-peers. Ninety-three percent of the children with CP were insufficiently physically active according to the Dutch recommendation for physical activity. Multiple regression analyses showed that younger age and lower educational level of the mother were significantly associated with lower levels of physical activity for children with CP, while severity of CP was not associated with physical activity levels. Twenty-two percent of the parents reported that more facilities in sport and games are required for children with CP. Conclusion. Physical activity is low in young children with CP and needs to be promoted at an early stage. [ABSTRACT FROM AUTHOR]
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- 2010
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17. Studies examining the efficacy of Ankle Foot Orthoses should report activity level and mechanical evidence.
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Harlaar J, Brehm M, Becher JG, Bregman DJ, Buurke J, Holtkamp F, De Groot V, and Nollet F
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- 2010
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18. Course of health-related quality of life in 9--16-year-old children with cerebral palsy: associations with gross motor abilities and mental health.
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Janssen CGC, Voorman JM, Becher JG, Dallmeijer AJ, and Schuengel C
- Abstract
Purpose. To chart the 3-year course of health-related quality of life (HRQoL) of 9-13-year-old children with cerebral palsy (CP), and to determine its relationship with gross motor abilities and mental health. Methods. Children ( n = 91; 58 boys, mean age 11 years, age ranging from 8 years and 6 months to 13 years and 8 months) and parents were assessed annually with the TNO-AZL questionnaires for children's health-related quality of life as a dependent variable, and the gross motor function measure for children with CP and the child behaviour check list as independent variables. Results. The children reported lower HRQoL compared with children in the general population, but reported a higher HRQoL than their parents. The HRQoL remained fairly stable over the 3 years, except for an increase in the autonomy domain. The HRQOL was moderately associated with gross motor abilities, and negatively associated with internalising mental health problems. Externalising problems were only negatively associated with parent-reported HRQoL. Conclusions. Children with CP are more resilient and positive about their HRQoL than their parents think they are. In general, mental health in children with CP appeared to be important in understanding their perceived QoL, in addition to the severity of the CP itself. [ABSTRACT FROM AUTHOR]
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- 2010
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19. Measuring mobility limitations in children with cerebral palsy: interrater and intrarater reliability of a mobility questionnaire (MobQues)
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Van Ravesteyn NT, Dallmeijer AJ, Scholtes VA, Roorda LD, and Becher JG
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AIM: The objective of this study was to assess the reliability of a mobility questionnaire (MobQues) that was developed to measure the mobility limitations of children with cerebral palsy (CP) as rated by their parents. A clinical version of the questionnaire, consisting of 47 items (MobQues47), is available, as well as a research version with 28 items for a specific population (MobQues28). Total scores are expressed on a scale of 0 to 100. METHOD: We assessed the interrater reliability between both parents of 289 children with CP (168 males, 121 females, age range 2-13 y, Gross Motor Function Classification System levels I-IV) and the intrarater reliability within a subgroup of 38 parents (of 23 children) who completed the MobQues twice. RESULTS: For the interrater reliability, high intraclass correlation coefficients (ICCs) were found for the MobQues47 (ICC 0.92) and MobQues28 (ICC 0.87). The standard error of measurement (SEM) was 7.8 and 8.9 respectively. As expected, the intrarater reliability was higher, as represented by higher ICCs (0.96-0.99) and lower SEMs (3.5-4.9) for both MobQues versions. INTERPRETATION: The results of this study indicate that the MobQues is a reliable instrument to measure the mobility limitations of children with CP. [ABSTRACT FROM AUTHOR]
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- 2010
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20. Motor testing at 1 year improves the prediction of motor and mental outcome at 2 years after perinatal hypoxic-ischaemic encephalopathy.
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van Schie PE, Becher JG, Dallmeijer AJ, Barkhof F, Van Weissenbruch MM, and Vermeulen RJ
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AIM: To investigate the predictive value of motor testing at 1 year for motor and mental outcome at 2 years after perinatal hypoxic-ischaemic encephalopathy (HIE) in term neonates. METHOD: Motor and mental outcome at 2 years was assessed with the Bayley Scales of Infant Development, 2nd edition (BSID-II) in 32 surviving children (20 males, 12 females; mean gestational age 40.2 wk, SD 1.4; mean birthweight 3217g, SD 435) participating in a prospective cohort study of HIE. The predictive value of three motor tests (Alberta Infant Motor Scale [AIMS], BSID-II, and the Neurological Optimality Score [NOS]) at 1 year was analysed, in addition to predictions based on neonatal Sarnat staging and magnetic resonance imaging (MRI). Poor motor test results were defined as an AIMS z-score of <-2, a psychomotor developmental index of the BSID-II of <70, or a NOS of <26. Poor motor and poor mental outcome at 2 years was defined as a psychomotor developmental index or mental developmental index of the BSID-II of <70. RESULTS: Twelve children, all with Sarnat grade II, had a poor motor outcome and 12 children, of whom one had Sarnat grade I, had a poor mental outcome at 2 years. Nine children had cerebral palsy, of whom five had quadriplegia, three had dyskinesia, and one had hemiplegia. Poor motor tests at 1 year increased the probability of a poor motor outcome from 71% (range 92 to 100%), and a poor mental outcome from 59% (range 77 to 100%) in children with Sarnat grade II and abnormal MRI, assessed with the AIMS and BSID-II or NOS respectively. INTERPRETATION: Additional motor testing at 1 year improves the prediction of motor and mental outcome at 2 years in children with Sarnat grade II and abnormal MRI. [ABSTRACT FROM AUTHOR]
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- 2010
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21. Clinical assessment of spasticity in children with cerebral palsy: a critical review of available instruments.
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Scholtes VAB, Becher JG, Beelen A, and Lankhorst GJ
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This study reviews the instruments used for the clinical assessment of spasticity in children with cerebral palsy, and evaluates their compliance with the concept of spasticity, defined as a velocity-dependent increase in muscle tone to passive stretch. Searches were performed in Medline, Embase, and Cinahl, including the keywords 'spasticity', 'child', and 'cerebral palsy', to identify articles in which a clinical method to measure spasticity was reported. Thirteen clinical spasticity assessment instruments were identified and evaluated using predetermined criteria. This review consists of reports on the standardization applied for assessment at different velocities, testing posture, and quantification of spasticity. Results show that most instruments do not comply with the concept of spasticity; standardization of assessment method is often lacking, and scoring systems of most instruments are ambiguous. Only the Tardieu Scale complies with the concept of spasticity, but this instrument has a comprehensive and time-consuming clinical scoring system. [ABSTRACT FROM AUTHOR]
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- 2006
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22. Pediatric rehabilitation in children with cerebral palsy: general management, classification of motor disorders.
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Becher JG
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- 2002
23. Measurement of impaired muscle function of the gastrocnemius, soleus, and tibialis anterior muscles in spastic hemiplegia: a preliminary study.
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Becher JG, Harlaar J, Lankhorst GJ, and Vogelaar TW
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Based on the results of several electrodiagnostic and biomechanical studies, the following classification of muscle dysfunction in spastic hemiplegia is proposed: changes in muscle activation (excess symptoms, e.g., spasticity, and deficit symptoms, e.g., paresis); changes in muscle stiffness; and changes in muscle length. The clinical significance of this classification is that different types of muscle dysfunction might require specific treatment. The authors have developed techniques to measure quantitatively each type of muscle dysfunction: free frequency repetitive movement (FFRM) and torque angle diagram (TAD). Surface EMGs of tibialis anterior, gastrocnemius, and soleus muscle are recorded during active (FFRM) and passive (TAD) ankle movements. EMG data are converted to parameters for abnormal muscle activation (excess and deficit symptoms). Parameters for muscle stiffness and muscle length are derived from the hysteresis curve of the TAD. This article describes the measurements and the results of a validation study. For the validation study, four hypotheses were formulated: 1) in nonimpaired control subjects, parameters expressing abnormal muscle activation are low; 2) in hemiplegic subjects, differences between the affected and the unaffected sides will be found for all types of parameters; 3) after local anaesthesia of the tibial nerve on the hemiplegic side, excess symptoms will decrease, while muscle stiffness remains unchanged; and 4) despite a uniform gait pattern, between-subject differences can be detected with regard to muscle activation, stiffness, and length. The first hypothesis was tested and confirmed in two controls; the remaining three were tested and confirmed in ten hemiplegic subjects (mean age 47.7 yrs, mean time since onset 10.7 yrs). However, the level of co-contraction of the gastrocnemius muscle was low, probably indicating that the clinical significance of this phenomenon might be limited. The results support the validity of the proposed classification and measurements. [ABSTRACT FROM AUTHOR]
- Published
- 1998
24. Letters to the editor. 'Satisfaction with intrathecal baclofen treatment in paediatric patients with progressive neurological disease'.
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Bonouvrié LA, van Schie PEM, Becher JG, van Ouwerkerk WJR, and Vermeulen RJ
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- 2008
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25. Effect of multilevel botulinum toxin A and comprehensive rehabilitation in cerebral palsy on mobility and gait 1 year after treatment.
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Scholtes VAB, Dallmeijer AJ, and Becher JG
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- 2006
26. Definition of a randomized controlled trial.
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Beckerman H, Becher JG, and Lankhorst GJ
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- 2005
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27. Utility of language comprehension tests for unintelligible or non-speaking children with cerebral palsy: a systematic review.
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Geytenbeek J, Harlaar L, Stam M, Ket H, Becher JG, Oostrom K, and Vermeulen J
- Abstract
AIM: to identify the use and utility of language comprehension tests for unintelligible or non-speaking children with severe cerebral palsy (CP). METHOD: severe CP was defined as severe dysarthria (unintelligible speech) or anarthria (absence of speech) combined with severe limited mobility, corresponding to Gross Motor Function Classification System levels IV to V. An electronic search in the databases of PubMed, PsychInfo, Embase, and CINAHL was made of studies published between January 1965 and December 2008. Indexing terms and free-text terms for 'cerebral palsy', 'language', and 'instrumentation' were used. Studies were included when (1) the focus was to investigate comprehension of spoken language of children (0-18 y) with severe CP, and (2) language tests were described. RESULTS: twelve standardized tests and five experimental instruments were identified. All standardized tests were developed for children without limited mobility. Only the Peabody Picture Vocabulary Test - Revised was frequently used and feasible for older children with severe CP (> 9 y). The other tests were used occasionally. To establish utility, adaptations of standardized test procedures were necessary. INTERPRETATION: language comprehension tests for children with severe CP are scarce. A language comprehension test specifically designed for these children is warranted. [ABSTRACT FROM AUTHOR]
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- 2010
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28. Measuring mobility limitations in children with cerebral palsy: content and construct validity of a mobility questionnaire (MobQues)
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VAN Ravesteyn NT, Scholtes VA, Becher JG, Roorda LD, Verschuren O, and Dallmeijer AJ
- Abstract
AIM: the objective of this study was to assess the validity of a mobility questionnaire (MobQues) that was developed to measure parent-reported mobility limitations in children with cerebral palsy (CP). METHOD: the parents of 439 children with CP (256 males and 183 females; age range 2-18y; Gross Motor Function Classification System [GMFCS] levels I-IV) completed the mobility questionnaire (MobQues). To assess content validity, we linked all meaningful concepts of the MobQues items to the International Classification of Functioning, Disability and Health (ICF). To assess construct validity, we compared the total scores of the two versions of the MobQues (MobQues47 and MobQues28) according to GMFCS level, and determined Pearson's correlation coefficient (r) with the Gross Motor Function Measure-66 (GMFM-66). RESULTS: content validity was demonstrated by the fact that 46 of the 47 MobQues items were linked to categories in the 'Mobility' chapter of the ICF. Construct validity was demonstrated by the finding that MobQues scores decreased with increasing GMFCS levels (p<0.001). In a subgroup of 162 children, positive correlations were found between total scores and the GMFM-66 (MobQues47, r=0.75; MobQues28, r=0.67, p<0.001). INTERPRETATION: the results of this study provide evidence supporting the content and construct validity of the MobQues as a measure of mobility limitation in children with CP. [ABSTRACT FROM AUTHOR]
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- 2010
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29. Lower limb strength training in children with cerebral palsy--a randomized controlled trial protocol for functional strength training based on progressive resistance exercise principles.
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Scholtes VA, Dallmeijer AJ, Rameckers EA, Verschuren O, Tempelaars E, Hensen M, and Becher JG
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Until recently, strength training in children with cerebral palsy (CP) was considered to be inappropriate, because it could lead to increased spasticity or abnormal movement patterns. However, the results of recent studies suggest that progressive strength training can lead to increased strength and improved function, but low methodological quality and incomplete reporting on the training protocols hampers adequate interpretation of the results. This paper describes the design and training protocol of a randomized controlled trial to assess the effects of a school-based progressive functional strength training program for children with CP.~Background~Background~Fifty-one children with Gross Motor Function Classification Systems levels I to III, aged of 6 to 13 years, were recruited. Using stratified randomization, each child was assigned to an intervention group (strength training) or a control group (usual care). The strength training was given in groups of 4-5 children, 3 times a week, for a period of 12 weeks. Each training session focussed on four exercises out of a 5-exercise circuit. The training load was gradually increased based on the child's maximum level of strength, as determined by the 8 Repetition Maximum (8 RM). To evaluate the effectiveness of the training, all children were evaluated before, during, directly after, and 6 weeks after the intervention period. Primary outcomes in this study were gross motor function (measured with the Gross Motor Function Measure and functional muscle strength tests) and walking ability (measured with the 10-meter, the 1-minute and the timed stair test). Secondary outcomes were lower limb muscle strength (measured with a 6 RM test, isometric strength tests, and a sprint capacity test), mobility (measured with a mobility questionnaire), and sport activities (measured with the Children's Assessment of Participation and Enjoyment). Spasticity and range of motion were assessed to evaluate any adverse events.~Methods/results~Results~Randomized clinical trials are considered to present the highest level of evidence. Nevertheless, it is of utmost importance to report on the design, the applied evaluation methods, and all elements of the intervention, to ensure adequate interpretation of the results and to facilitate implementation of the intervention in clinical practice if the results are positive.~Conclusion~Conclusions~Trial Register NTR1403.~Trial Registration~Background [ABSTRACT FROM AUTHOR]
- Published
- 2008
30. Validity of the Dutch ABILHAND-Kids in adolescents with cerebral palsy.
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Dallmeijer AI, Van Eck M, Roebroeck M, and Becher JG
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- 2007
31. Short- and long-term effects of selective dorsal rhizotomy on gross motor function in children with cerebral palsy.
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Schothorst M, Van Schie PEM, Dallmeijer AJ, and Becher JG
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- 2007
32. Physical strain of walking in children with cerebral palsy.
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Dallmeijer AJ, Brehm MA, De Haas LMJ, and Becher JG
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- 2006
33. Physical activity level and sports participation of adolescents of 12 to 16 years with cerebral palsy.
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Van Eck M, Dallmeijer AJ, Beckerman H, Voorman JM, and Becher JG
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- 2006
34. Botulinum toxin A injections do not improve surface EMG patterns during gait in children with cerebral palsy-A randomized controlled study.
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van der Houwen LE, Scholtes VA, Becher JG, and Harlaar J
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- 2011
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35. Arithmetic performance of children with cerebral palsy: The influence of cognitive and motor factors.
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van Rooijen M, Verhoeven L, Smits DW, Ketelaar M, Becher JG, and Steenbergen B
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- 2012
36. Attainment of personal goals in the first year of intrathecal baclofen treatment in dyskinetic cerebral palsy: a prospective cohort study.
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Bonouvrié LA, Haberfehlner H, Becher JG, Vles JSH, Vermeulen RJ, and Buizer AI
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- Child, Humans, Young Adult, Baclofen therapeutic use, Goals, Injections, Spinal adverse effects, Injections, Spinal methods, Pain etiology, Prospective Studies, Cohort Studies, Cerebral Palsy, Dystonia drug therapy, Dystonia chemically induced, Muscle Relaxants, Central therapeutic use
- Abstract
Purpose: To assess attainment of individual treatment goals one year after intrathecal baclofen (ITB) pump implantation in individuals with dyskinetic cerebral palsy (CP)., Materials and Methods: A multi-center prospective cohort study was conducted including 34 non-walking individuals with severe dyskinetic CP, classified as Gross Motor Function Classification System (GMFCS) IV/V, aged 4-24 years, 12 months after pump implantation. The main outcome measure was Goal Attainment Scaling (GAS). Predictors of GAS results were analyzed. Complications were registered systematically., Results: Seventy-one percent of individuals with dyskinetic CP fully achieved one or more treatment goals. One or more treatment goals were partially achieved in 97% of individuals. Two factors were found to be associated with attainment of goals: Dyskinesia Impairment Scale (DIS) score at baseline and the difference in pain score between baseline and follow-up. These two variables explain 30% of the variance in the outcome., Conclusions: Intrathecal baclofen is effective in achieving individual treatment goals in children and young adults with dyskinetic CP after nine to 12 months of ITB treatment. A positive outcome on treatment goals is, for a small part, associated with higher severity of dystonia at baseline and with improvement of pain during treatment., Clinical Trial Registration Number: Dutch Trial Register, number NTR3642.Implications for rehabilitationIntrathecal baclofen treatment is effective in attainment of personal treatment goals, one year after pump implantation in patients with dyskinetic cerebral palsy.A positive outcome on treatment goals is, for a small part, related to higher severity of dystonia at the start and on improvement of pain during treatment.
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- 2023
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37. Improvements in Muscle Strength Are Associated With Improvements in Walking Capacity in Young Children With Cerebral Palsy: A Secondary Analysis.
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van Vulpen LF, de Groot S, Rameckers EAA, Becher JG, and Dallmeijer AJ
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- Child, Child, Preschool, Exercise Test, Female, Humans, Isometric Contraction physiology, Lower Extremity physiopathology, Male, Muscle Strength physiology, Muscle, Skeletal physiopathology, Walk Test, Cerebral Palsy physiopathology, Cerebral Palsy rehabilitation, Walking physiology
- Abstract
Purpose: To evaluate whether changes in lower-limb muscle strength explain changes in walking capacity during 14-week periods of usual care, power training and follow-up for children with spastic cerebral palsy., Methods: Secondary analysis of a previously conducted double-baseline controlled trial of 22 children with spastic cerebral palsy. Generalized estimating equations were used to evaluate the relationships between within-subject changes in isometric muscle strength and walking capacity over 3 periods., Results: Changes in hip abductor strength were associated with changes in the Muscle Power Sprint Test, changes in gastrocnemius and hip abductor strength were associated with changes in the Shuttle Run Test, and changes in gastrocnemius strength were associated with changes in the 1-minute walk test. All associations supported better walking capacity with increased strength., Conclusion: Walking capacity, especially sprint capacity, can be improved by increasing strength by functional power training in this population., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2020 Academy of Pediatric Physical Therapy of the American Physical Therapy Association.)
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- 2021
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38. Gastrocnemius Medialis Muscle Geometry and Extensibility in Typically Developing Children and Children With Spastic Paresis Aged 6-13 Years.
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Weide G, Huijing PA, Bar-On L, Sloot L, Buizer AI, Becher JG, Harlaar J, and Jaspers RT
- Abstract
Gait of children with spastic paresis (SP) is frequently characterized by a reduced ankle range of motion, presumably due to reduced extensibility of the triceps surae (TS) muscle. Little is known about how morphological muscle characteristics in SP children are affected. The aim of this study was to compare gastrocnemius medialis (GM) muscle geometry and extensibility in children with SP with those of typically developing (TD) children and assess how GM morphology is related to its extensibility. Thirteen children with SP, of which 10 with a diagnosis of spastic cerebral palsy and three with SP of unknown etiology (mean age 9.7 ± 2.1 years; GMFCS: I-III), and 14 TD children (mean age 9.3 ± 1.7 years) took part in this study. GM geometry was assessed using 3D ultrasound imaging at 0 and 4 Nm externally imposed dorsal flexion ankle moments. GM extensibility was defined as its absolute length change between the externally applied 0 and 4 Nm moments. Anthropometric variables and GM extensibility did not differ between the SP and TD groups. While in both groups, GM muscle volume correlated with body mass, the slope of the regression line in TD was substantially higher than that in SP (TD = 3.3 ml/kg; SP = 1.3 ml/kg, p < 0.01). In TD, GM fascicle length increased with age, lower leg length and body mass, whereas in SP children, fascicle length did not correlate with any of these variables. However, the increase in GM physiological cross-sectional area as a function of body mass did not differ between SP and TD children. Increases in lengths of tendinous structures in children with SP exceeded those observed in TD children (TD = 0.85 cm/cm; SP = 1.16 cm/cm, p < 0.01) and even exceeded lower-leg length increases. In addition, only for children with SP, body mass ( r = -0.61), height ( r = -0.66), muscle volume ( r = - 0.66), physiological cross-sectional area ( r = - 0.59), and tendon length ( r = -0.68) showed a negative association with GM extensibility. Such negative associations were not found for TD children. In conclusion, physiological cross-sectional area and length of the tendinous structures are positively associated with age and negatively associated with extensibility in children with SP., (Copyright © 2020 Weide, Huijing, Bar-On, Sloot, Buizer, Becher, Harlaar and Jaspers.)
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- 2020
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39. Ankle foot orthoses in cerebral palsy: Effects of ankle stiffness on trunk kinematics, gait stability and energy cost of walking.
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Meyns P, Kerkum YL, Brehm MA, Becher JG, Buizer AI, and Harlaar J
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- Biomechanical Phenomena, Cerebral Palsy physiopathology, Child, Female, Gait Disorders, Neurologic physiopathology, Humans, Male, Range of Motion, Articular, Walk Test, Walking physiology, Ankle physiopathology, Cerebral Palsy rehabilitation, Energy Metabolism physiology, Foot Orthoses, Gait Disorders, Neurologic rehabilitation
- Abstract
In children with cerebral palsy (CP), rigid ventral shell ankle-foot orthoses (vAFOs) are often prescribed to reduce excessive knee flexion in stance and lower the energy cost of walking (ECW). However, how vAFOs affect ECW is a complex issue, as vAFOs may have an impact on lower limb biomechanics, upper body movements, and balance. Besides, the vAFO's biomechanical effect have been shown to be dependent on its stiffness around the ankle joint. We examined whether vAFO stiffness influences trunk movements and gait stability in CP, and whether there is a relationship between these factors and ECW. Fifteen children with spastic CP were prescribed vAFOs. Stiffness was varied into a rigid, stiff and flexible configuration. At baseline (shoes-only) and for each vAFO stiffness configuration, 3D-gait analyses and ECW-tests were performed. From the gait analyses, we derived trunk tilt, lateroflexion, and rotation range of motion (RoM) and the mediolateral and anteroposterior Margins of Stability (MoS) and their variability as measures of gait stability. With the ECW-test we determined the netEC. We found that wearing vAFOs significantly increased trunk lateroflexion (Wald χ2 = 33.7, p < 0.001), rotation RoM (Wald χ2 = 20.5, p < 0.001) and mediolateral gait instability (Wald χ2 = 10.4, p = 0.016). The extent of these effects partly depended on the stiffness of the vAFO. Significant relations between trunk movements, gait stability and ECW were found r = 0.57-0.81, p < 0.05), which indicates that trunk movements and gait stability should be taken into account when prescribing vAFOs to improve gait in children with CP walking with excessive knee flexion., Competing Interests: Declaration of competing interest YK is currently employed by OIM Orthopedie, the company that manufactured all orthoses for the study. However, at the time the study was conducted, she was employed by Amsterdam UMC (as a PhD-student) and had no (financial) relation to OIM in any way., (Copyright © 2020 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.)
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- 2020
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40. Use of the Dyskinesia Impairment Scale in non-ambulatory dyskinetic cerebral palsy.
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Haberfehlner H, Bonouvrié LA, Boeschoten K, Fleuren S, Monbaliu E, Becher JG, Vermeulen RJ, and Buizer AI
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- Adolescent, Baclofen administration & dosage, Baclofen therapeutic use, Cerebral Palsy drug therapy, Cerebral Palsy physiopathology, Child, Disability Evaluation, Dyskinesias drug therapy, Dyskinesias physiopathology, Female, Humans, Injections, Spinal, Male, Muscle Relaxants, Central administration & dosage, Muscle Relaxants, Central therapeutic use, Severity of Illness Index, Treatment Outcome, Young Adult, Cerebral Palsy diagnosis, Dyskinesias diagnosis
- Abstract
Aim: To assess the responsiveness, concurrent validity, and feasibility of the Dyskinesia Impairment Scale (DIS) in non-ambulatory patients with dyskinetic cerebral palsy (CP)., Method: The study is a secondary analysis of data collected in the IDYS trial, a randomized controlled trial on the effects of intrathecal baclofen (ITB). The DIS and Barry-Albright Dystonia Scale (BADS) were conducted at baseline and after 3 months of ITB or placebo treatment. Responsiveness was assessed by comparing the effect sizes and correlation of change after treatment between the DIS and BADS. Concurrent validity was evaluated by assessing the correlations between scales. Feasibility was evaluated for each DIS item by the number of participants who successfully accomplished the item., Results: Thirty-three non-ambulatory patients (9 females, 24 males) with dyskinetic CP (ITB-treated: n=17, mean [SD] age: 14y 1mo [4y 1mo]; placebo-treated: n=16, mean [SD] age: 14y 7mo [4y]) were included in the study. The effect sizes for BADS and DIS were similar in The ITB-treated group (-0.29 and -0.22 respectively). Changes after treatment on the DIS dystonia subscale correlated with changes on the BADS (r=0.64; p<0.001). The DIS dystonia subscale and BADS correlated at baseline and follow-up (r=0.78; p<0.001 and r=0.79; p<0.001). Not all DIS activity items could be performed in this sample of patients., Interpretation: For non-ambulatory patients with dyskinetic CP, the responsiveness of the DIS equalled the responsiveness of BADS. Concurrent validity was adequate. Feasibility for activity items was restricted in patients with severe dyskinetic CP., What This Paper Adds: The Dyskinesia Impairment Scale (DIS) and Barry-Albright Dystonia Scale showed similar responsiveness in non-ambulatory patients with dyskinetic cerebral palsy (CP). No floor or ceiling effect was observed for DIS in non-ambulatory participants. The concurrent validity of DIS was adequate in non-ambulatory participants. Patients with dyskinetic CP in Gross Motor Function Classification System levels IV and V could not perform all DIS activity items., (© 2019 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press.)
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- 2020
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41. Foot flexibility confounds the assessment of triceps surae extensibility in children with spastic paresis during typical physical examinations.
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Weide G, Huijing PA, Becher JG, Jaspers RT, and Harlaar J
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- Adolescent, Child, Child, Preschool, Female, Humans, Male, Foot physiopathology, Muscle Spasticity complications, Muscle, Skeletal physiopathology, Paresis physiopathology, Physical Examination
- Abstract
Accurate assessment of the talo-crural (ankle) joint angle at physical examination is important for assessing extensibility of m. triceps surae (TS) in children with spastic cerebral paresis (SCP). The main aim of this study was to quantify foot flexibility during standardized measurements of TS muscle-tendon complex extensibility (i.e. based on foot-sole rotation) in SCP children, and typical developed (TD) ones. Additionally, we aim to define a method that minimizes the confounding effects of foot flexibility on estimates of talo-crural joint angles and TS extensibility. Children, aged 6-13 years, with SCP (GMFCS I-III, n = 13) and TD children (n = 14) participated in this study. Externally applied -1 Nm, 0 Nm, 1 Nm and 4 Nm dorsal flexion foot plate moments were imposed. Resulting TS origin-insertion lengths, foot sole (φ
FoSo ) rotations, and changes in talo-crural joint angle (φTaCr ) were measured. Foot flexibility was quantified as Δ(φTaCr -φFoSo ) between the 0 Nm and 4 Nm dorsal flexion conditions. In both groups, φFoSo rotations of approximately 20° were observed between 0 Nm and 4 Nm dorsal flexion, of which about 6° (≈30%) was related to foot flexibility. Foot flexibility correlated to φFoSo (r = 0.69) but not to φTaCr (r = 0.11). For φFoSo no significant differences were found between groups at 4 Nm. However, for SCP children the mean estimate of φTaCr was 4.3° more towards plantar flexion compared to the TD group (p < 0.05). Normalized TS lengths show a higher coefficient of correlation with φTaCr (r2 = 0.82) than with φFoSo (r2 = 0.60), indicating that TS lengths are better estimated by talo-cural joint angles. In both SCP and TD children aged 6-13 year, estimates of TS length and extensibility based on foot sole assessments are confounded by foot flexibility. Assessments of TS extensibility at physical examination will be more accurate when based on measurements of talo-crural joint angles., (Copyright © 2019. Published by Elsevier Ltd.)- Published
- 2020
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42. The Effect of Intrathecal Baclofen in Dyskinetic Cerebral Palsy: The IDYS Trial.
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Bonouvrié LA, Becher JG, Vles JSH, Vermeulen RJ, and Buizer AI
- Subjects
- Adolescent, Adult, Child, Child, Preschool, Double-Blind Method, Female, Humans, Injections, Spinal, Male, Treatment Outcome, Young Adult, Baclofen administration & dosage, Cerebral Palsy diagnosis, Cerebral Palsy drug therapy, Muscle Relaxants, Central administration & dosage
- Abstract
Objective: Intrathecal baclofen treatment is used for the treatment of dystonia in patients with severe dyskinetic cerebral palsy; however, the current level of evidence for the effect is low. The primary aim of this study was to provide evidence for the effect of intrathecal baclofen treatment on individual goals in patients with severe dyskinetic cerebral palsy., Methods: This multicenter, randomized, double-blind, placebo-controlled trial was performed at 2 university medical centers in the Netherlands. Patients with severe dyskinetic cerebral palsy (Gross Motor Functioning Classification System level IV-V) aged 4 to 24 years who were eligible for intrathecal baclofen were included. Patients were assigned by block randomization (2:2) for treatment with intrathecal baclofen or placebo for 3 months via an implanted microinfusion pump. The primary outcome was goal attainment scaling of individual treatment goals (GAS T score). A linear regression model was used for statistical analysis with study site as a covariate. Safety analyses were done for number and type of (serious) adverse events., Results: Thirty-six patients were recruited from January 1, 2013, to March 31, 2018. Data for final analysis were available for 17 patients in the intrathecal baclofen group and 16 in the placebo group. Mean (standard deviation) GAS T score at 3 months was 38.9 (13.2) for intrathecal baclofen and 21.0 (4.6) for placebo (regression coefficient = 17.8, 95% confidence interval = 10.4-25.0, p < 0.001). Number and types of (serious) adverse events were similar between groups., Interpretation: Intrathecal baclofen treatment is superior to placebo in achieving treatment goals in patients with severe dyskinetic cerebral palsy. ANN NEUROL 2019., (© 2019 The Authors. Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association.)
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- 2019
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43. Intrathecal baclofen in metachromatic leukodystrophy.
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van der Veldt N, van Rappard DF, van de Pol LA, van der Knaap MS, van Ouwerkerk WJR, Becher JG, Wolf NI, and Buizer AI
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- Adolescent, Child, Female, Humans, Infusion Pumps, Implantable, Injections, Spinal, Male, Retrospective Studies, Treatment Outcome, Young Adult, Baclofen administration & dosage, Leukodystrophy, Metachromatic drug therapy, Muscle Relaxants, Central administration & dosage
- Abstract
Metachromatic leukodystrophy (MLD) is a rare progressive neurological disorder, often accompanied by motor impairments that are challenging to treat. In this case series, we report the course of treatment with intrathecal baclofen (ITB), aimed at improving daily care and comfort in children and young adults with MLD. All patients with MLD in our centre on ITB treatment for a minimum of 6 months were included (n=10; 4 males, 6 females; mean age 10y 8mo [range 6-24y]). Eight patients had MLD with a predominant spastic movement disorder (sMLD) and two were mainly dyskinetic. Patients with sMLD were compared with matched patients with spastic cerebral palsy (CP). Complication rates related to ITB treatment were similar in both groups. ITB treatment course in the first 6 months after pump implantation appears to show more dose increase in most patients MLD, compared to patients with spastic CP. This may be due to the progressive disease in MLD. ITB is a feasible therapy to improve daily care and comfort in patients with MLD and should therefore be considered early. WHAT THIS PAPER ADDS: Intrathecal baclofen (ITB) is a feasible therapy to improve comfort and daily care in children and young people with metachromatic leukodystrophy (MLD). In the first 6 months of ITB treatment, MLD seems to show more dose increase compared to spastic cerebral palsy., (© 2018 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press.)
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- 2019
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44. Effect of continuous intrathecal baclofen therapy in children: a systematic review.
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Buizer AI, Martens BHM, Grandbois van Ravenhorst C, Schoonmade LJ, Becher JG, and Vermeulen RJ
- Subjects
- Child, Child, Preschool, Cohort Studies, Humans, Infusion Pumps, Implantable, Baclofen administration & dosage, Cerebral Palsy drug therapy, GABA-B Receptor Agonists administration & dosage, Injections, Spinal methods
- Abstract
Aim: To investigate the effects of continuous intrathecal baclofen (ITB) therapy in children with cerebral palsy (CP) and other neurological conditions., Method: This systematic review was conducted using standardized methodology, searching four electronic databases (PubMed, Embase, CINAHL, Cochrane Library) for relevant literature published between inception and September 2017. Included studies involved continuous ITB as an intervention and outcome measures relating to all International Classification of Functioning, Disability and Health: Children and Youth (ICF-CY) components., Results: Thirty-three studies were identified, of which one, including 17 children with spastic CP, produced level II evidence, and the others, mainly non-controlled cohort studies, level IV and V. Outcomes at body function level were most frequently reported. Results suggest continuous ITB may be effective in reducing spasticity and dystonia in CP, as well as other neurological conditions, and may improve the ease of care and quality of life of children with CP, but the level of evidence is low., Interpretation: Despite three decades of applying ITB in children and a relatively large number of studies investigating the treatment effects, a direct link has not yet been demonstrated because of the low scientific quality of the primary studies. Further investigation into the effects of continuous ITB at all levels of the ICF-CY is warranted. Although large, controlled trials may be difficult to realize, national and international collaborations may provide opportunities. Also, multicentre prospective cohort studies with a long-term follow-up, employing harmonized outcome measures, can offer prospects to expand our knowledge of the effects of continuous ITB therapy in children., What This Paper Adds: There is low-level evidence for continuous intrathecal baclofen (ITB) in children with cerebral palsy. Continuous ITB is effective in reducing spasticity and dystonia in non-controlled cohort studies. Evaluation of individual goals and systematic assessment of long-term effects in large cohort studies are required., (© 2018 The Authors Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press.)
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- 2019
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45. Improved parent-reported mobility and achievement of individual goals on activity and participation level after functional power-training in young children with cerebral palsy: a double-baseline controlled trial.
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van Vulpen LF, de Groot S, Rameckers EA, Becher JG, and Dallmeijer AJ
- Subjects
- Child, Child, Preschool, Exercise Therapy methods, Female, Goals, Humans, Male, Parents psychology, Treatment Outcome, Activities of Daily Living, Cerebral Palsy therapy, Resistance Training methods, Walking physiology
- Abstract
Background: In children with cerebral palsy (CP), strength training programs to improve walking capacity and participation in activities of daily living are commonly used in clinical practice, despite lacking evidence of its effectiveness. It has been suggested that strength training with high movement velocity could be more effective than traditional resistance training to improve functional abilities such as walking. In a recently published study, we have demonstrated the positive effects of functional high-velocity resistance (power) training on muscle strength and walking capacity in young children with CP. Whether this type of training is also effective in achieving individual predefined goals in daily activities and self-reported mobility limitations, has not yet been described however., Aim: To evaluate the effect of functional power-training on parent-reported mobility and achievement of individual goals on activity and participation level in young children with CP., Design: A double-baseline design was used to compare a 14-week period usual care with a 14-week period of functional power-training (3 times a week) and a follow-up period of 14 weeks., Setting: A rehabilitation center, two special needs schools for children with physical disabilities, and a university medical center outpatient clinic., Population: Twenty-two children with spastic CP (13 bilateral, GMFCS level I [N.=10] and level II [N.=12], mean age 7.5 years [SD 1.8, range 4-10 years]) and their parents participated., Methods: Outcome measures were goal attainment scaling (GAS) of individual daily activity related treatment goals, mobility performance as measured using the Functional Mobility Scale (FMS-5 m, 50 m and 500 m), and the parent-reported Mobility Questionnaire (MobQues)., Results: After power-training, 86% of children achieved or exceeded their goal, compared with 14% in the usual care period (P<.001). The probability of improvement by one point or more on the FMS-500 meter after functional power-training was 10 times higher, compared with the usual care period (Relative Risk=10.0 with 95% CI 1.4 - 71.3). No changes were found in the FMS-5m and FMS-50m categories. Improvement on the MobQues was significantly greater after power-training compared with usual care (7.9% (95% CI 2.7 - 13.0, P=.005)). The improvement in performance in the activities defined in the treatment goals continued during the follow-up period., Conclusions and Clinical Rehabilitation Impact: The results indicated that functional power-training is an effective training to achieve personalized treatment goals for activities in daily life and parent-reported mobility performance in young children with cerebral palsy.
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- 2018
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46. Outcome of medial hamstring lengthening in children with spastic paresis: A biomechanical and morphological observational study.
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Haberfehlner H, Jaspers RT, Rutz E, Harlaar J, van der Sluijs JA, Witbreuk MM, van Hutten K, Romkes J, Freslier M, Brunner R, Becher JG, Maas H, and Buizer AI
- Subjects
- Adolescent, Anthropometry, Biomechanical Phenomena, Cerebral Palsy pathology, Cerebral Palsy physiopathology, Child, Female, Gait, Hamstring Muscles pathology, Hamstring Muscles physiopathology, Humans, Knee Joint physiopathology, Male, Muscle Spasticity pathology, Muscle Spasticity physiopathology, Muscle Spasticity surgery, Prospective Studies, Treatment Outcome, Cerebral Palsy surgery, Hamstring Muscles surgery, Tenotomy methods
- Abstract
To improve gait in children with spastic paresis due to cerebral palsy or hereditary spastic paresis, the semitendinosus muscle is frequently lengthened amongst other medial hamstring muscles by orthopaedic surgery. Side effects on gait due to weakening of the hamstring muscles and overcorrections have been reported. How these side effects relate to semitendinosus morphology is unknown. This study assessed the effects of bilateral medial hamstring lengthening as part of single-event multilevel surgery (SEMLS) on (1) knee joint mechanics (2) semitendinosus muscle morphology and (3) gait kinematics. All variables were assessed for the right side only. Six children with spastic paresis selected for surgery to counteract limited knee range of motion were measured before and about a year after surgery. After surgery, in most subjects popliteal angle decreased and knee moment-angle curves were shifted towards a more extended knee joint, semitendinosus muscle belly length was approximately 30% decreased, while at all assessed knee angles tendon length was increased by about 80%. In the majority of children muscle volume of the semitendinosus muscle decreased substantially suggesting a reduction of physiological cross-sectional area. Gait kinematics showed more knee extension during stance (mean change ± standard deviation: 34±13°), but also increased pelvic anterior tilt (mean change ± standard deviation: 23±5°). In most subjects, surgical lengthening of semitendinosus tendon contributed to more extended knee joint angle during static measurements as well as during gait, whereas extensibility of semitendinosus muscle belly was decreased. Post-surgical treatment to maintain muscle belly length and physiological cross-sectional area may improve treatment outcome of medial hamstring lengthening.
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- 2018
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47. Erratum: Risk Factors for Dystonia after Selective Dorsal Rhizotomy in Nonwalking Children and Adolescents with Bilateral Spasticity.
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van de Pol LA, Vermeulen RJ, van 't Westende C, van Schie PEM, Bolster EAM, van Ouwerkerk PWJR, Strijers RL, Becher JG, Stadhouder A, de Graaf P, and Buizer AI
- Abstract
Competing Interests: Disclosure The authors report no conflicts of interest in this work.
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- 2018
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48. Risk Factors for Dystonia after Selective Dorsal Rhizotomy in Nonwalking Children and Adolescents with Bilateral Spasticity.
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van de Pol LA, Vermeulen RJ, van 't Westende C, van Schie PEM, Bolster EAM, van Ouwerkerk PWJR, Strijers RL, Becher JG, Stadhouder A, de Graaf P, and Buizer AI
- Subjects
- Adolescent, Caregivers psychology, Chi-Square Distribution, Child, Child, Preschool, Dystonia diagnostic imaging, Female, Humans, Magnetic Resonance Imaging, Male, Postoperative Complications diagnostic imaging, Retrospective Studies, Risk Factors, Young Adult, Dystonia etiology, Muscle Spasticity surgery, Postoperative Complications physiopathology, Rhizotomy adverse effects
- Abstract
We recently showed a beneficial effect of selective dorsal rhizotomy (SDR) on daily care and comfort in nonwalking children with severe bilateral spasticity. However, despite careful selection, some patients showed dystonia after the intervention, in which cases caregivers tended to be less satisfied with the result.The aim of this study is to identify risk factors for dystonia after SDR in children and adolescents with severe bilateral spasticity (GMFCS levels IV/V).Clinical and MRI risk factors for dystonia after SDR were studied in our cohort of 24 patients. Patients with clinical evidence of dystonia and brain MRI showing basal ganglia abnormalities were excluded for SDR.Nine of 24 patients (38%) showed some degree of dystonia after SDR. There was a significant association between the cause of spasticity and dystonia after SDR; in six (67%) patients with a congenital disorder, dystonia was present versus three (20%) with an acquired disorder (Chi-squared test: C(1) = 5.23, p = 0.02).This study allows more optimal selection of patients that may benefit from SDR. Patients with an acquired cause of spasticity, when selected carefully on clinical examination and MRI, rarely show dystonia after SDR. However, patients with an underlying congenital disorder have a considerable risk of dystonia after SDR., Competing Interests: Conflict of Interest: None., (Georg Thieme Verlag KG Stuttgart · New York.)
- Published
- 2018
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49. Measuring wearing time of knee-ankle-foot orthoses in children with cerebral palsy: comparison of parent-report and objective measurement.
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Maas JC, Dallmeijer AJ, Oudshoorn BY, Bolster EAM, Huijing PA, Jaspers RT, and Becher JG
- Subjects
- Child, Female, Humans, Male, Time Factors, Cerebral Palsy rehabilitation, Foot Orthoses, Parents, Telemetry
- Abstract
Purpose state: Orthotic wearing time may be an important confounder in efficacy studies of treatment in children with spastic cerebral palsy (SCP). Most studies measure parent-reported wearing time (WT
parent ) with questionnaires, but it is questionable whether this yields valid results. This study aims to compare WTparent with objectively measured wearing time (WTobj ) in children with SCP receiving orthotic treatment., Method: Eight children with SCP participated in this observational study. For one year, they received knee-ankle-foot orthosis (KAFO) treatment. WTparent was measured using questionnaires. WTobj was measured using temperature sensor-data-loggers that were attached to the KAFOs. The 2.5th and 97.5th percentiles and median of differences between methods (per participant) were used to calculate limits of agreement and systematic differences., Results: There was no systematic difference between WTparent and WTobj (0.1 h per week), but high inter-individual variation of the difference was found, as reflected by large limits of agreement (lower limit/2.5th percentile: -1.7 h/week; upper limit/97.5th percentile: 11.1 h/week)., Conclusions: Parent-reported wearing time (WTparent) of a KAFO differs largely from objectively measured wearing time (WTobj ) using temperature sensors. Therefore, parent-reported wearing time (WTparent ) of KAFOs should be interpreted with utmost care. Implications for Rehabilitation Low wearing time of orthoses may be a cause of inefficacy of orthotic treatment and incorrect reported wearing time may bias results of efficacy studies. Results of this study show that parent-reported wearing time is not in agreement with objectively measured wearing time. Parent-reported wearing time of KAFOs should be interpreted with utmost care. Objective methods are recommended for measuring orthotic wearing time.- Published
- 2018
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50. Improved Walking Capacity and Muscle Strength After Functional Power-Training in Young Children With Cerebral Palsy.
- Author
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van Vulpen LF, de Groot S, Rameckers E, Becher JG, and Dallmeijer AJ
- Subjects
- Child, Child, Preschool, Female, Gait Disorders, Neurologic rehabilitation, Humans, Lower Extremity physiopathology, Male, Treatment Outcome, Cerebral Palsy complications, Cerebral Palsy rehabilitation, Gait Disorders, Neurologic etiology, Muscle Strength physiology, Resistance Training methods, Walking physiology
- Abstract
Background: Strength training programs for children with cerebral palsy (CP) showed inconclusive evidence for improving walking, despite improvements in strength. Recent studies have suggested that strength training with high movement velocity is more effective for improving walking than traditional resistance training., Objective: The purpose of this study was to evaluate the effect of functional high-velocity resistance training (power-training) to improve muscle strength and walking capacity of children with CP., Method: Twenty-two children with spastic CP participated (13 bilateral, Gross Motor Function Classification System [GMFCS] level I [n = 10] and II [n = 12], 7.5 years [SD 1.8, range 4-10 years]). Within-subjects changes in a 14-weeks usual care period were compared with changes in a 14-week functional power-training period (in groups, 3×/wk). Outcome measures were the muscle power sprint test (MPST), 1-minute walk test (1MWT), 10-m shuttle run test (SRT), gross motor function (GMFM-66), isometric strength of lower-limb muscles and dynamic ankle plantar flexor strength., Results: Changes during the training period were significantly larger than changes in the usual care period for all outcome measures ( P < .05). Large improvements were found during the training period for walking capacity (ΔMPST [mean]: 27.6 W [95%CI 15.84-39.46, 83% increase], Δ1MWT: 9.4 m [95% CI 4.17-14.68, 13%], ΔSRT: 4.2 [95%CI 2.57-5.83, 56%], ΔGMFM-66: 5.5 [95% CI 3.33-7.74, 7%]) and muscle strength (18%-128%), while outcomes remained stable in the usual care period., Conclusions: The results indicate that functional power-training is an effective training for improving walking capacity in young children with cerebral palsy.
- Published
- 2017
- Full Text
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