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154 results on '"Bayle, Nicolas"'

5. Validity of movement smoothness metrics for upper limb reaching movements in people with moderate to severe subacute stroke

Author

CORNEC, Gwenaël, primary, LEMPEREUR, Mathieu, additional, MENSAH-GOURMEL, Johanne, additional, ROBERTSON, Johanna, additional, MIRAMAND, Ludovic, additional, MEDEE, Beatrice, additional, BELLAICHE, Soline, additional, GROSS, Raphael, additional, GRACIES, Jean-Michel, additional, REMY-NERIS, Olivier, additional, and BAYLE, Nicolas, additional

Published
2024
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6. Use of Botulinum Toxin in Upper-Limb Tremor: Systematic Review and Perspectives.

Author

Motavasseli, Damien, Delorme, Cécile, Bayle, Nicolas, Gracies, Jean-Michel, Roze, Emmanuel, and Baude, Marjolaine

Subjects
BOTULINUM toxin, BOTULINUM A toxins, ESSENTIAL tremor, RANDOMIZED controlled trials, MOVEMENT disorders, WRIST
Abstract

Background: Tremor is the most common movement disorder, with significant functional and psychosocial consequences. Oral medications have been disappointing or limited by side effects. Surgical techniques are effective but associated with risks and adverse events. Botulinum toxin (BT) represents a promising avenue but there is still no double-blind evidence of efficacy on upper limb function. A systematic review on the effects of BT in upper-limb tremor was conducted. Methods: A systematic search of the literature was conducted up to July 2023, including the keywords "botulinum toxin" and "tremor". All randomized controlled trials (RCTs) and open-label studies were analyzed. Independent reviewers assessed their methodological quality. Results: There were only eight published RCTs and seven published open-label studies, with relatively small sample sizes. This review suggests that BT is more effective when injections are patient-tailored, with analyses based on clinical judgement or kinematics. Subjective and objective measures frequently improve but transient weakness may occur after injections, especially if wrist or fingers extensors are targeted. A number of studies had methodological limitations. Conclusions: The authors discuss how to optimize tremor assessments and effects of BT injection. Controlled evidence is still lacking but it is suggested that distal "asymmetric" BT injections (targeting flexors/pronators while sparing extensors/supinators) and proximal injections, involving shoulder rotators when indicated, may avoid excessive weakness while optimizing functional benefit. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Contributors

Author

Diong, Joanna, Heroux, Martin, Bayle, Nicolas, Butler, Jane, and Gandevia, Simon

Published
2022
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19. Worldwide Survey of Clinician Practice on use of Adjunctive Therapies Following Botulinum Toxin Injection for Spasticity

Author

Schillebeeckx, Fabienne, primary, Mills, Patricia B., additional, Ip, Alvin, additional, Schinwelski, Michal, additional, Teixeira, Joao Eduardo Marten, additional, Ashford, Stephen, additional, Bayle, Nicolas, additional, Chemello, Elena, additional, Jacinto, Jorge, additional, Nayar, Meenakshi, additional, Suzigan, Erika, additional, and Deltombe, Thierry, additional

Published
2022
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25. Contributors

Author

Alhusaini, Adel Abdullah, primary, Anderson, David I., additional, Barbu-Roth, Marianne, additional, Bayle, Nicolas, additional, Belmonti, Vittorio, additional, Boyd, Roslyn, additional, Campos, Joseph J., additional, Cioni, Giovanni, additional, Dahl, Audun, additional, Damiano, Diane L., additional, Einspieler, Christa, additional, Eyre, Janet, additional, Fetters, Linda, additional, Galea, Mary P., additional, Gordon, Andrew M., additional, Gough, Martin, additional, Gracies, Jean-Michel, additional, Guzzetta, Andrea, additional, Lieber, Richard L., additional, Nielsen, Jens Bo, additional, Perez, Micah, additional, Rivera, Monica, additional, Shepherd, Roberta B., additional, Shortland, Adam P., additional, Smith, Lucas R., additional, Teulier, Caroline, additional, and Uchiyama, Ichiro, additional

Published
2014
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27. Quantified clinical measures linked to ambulation speed in hemiparesis.

Author

Ghédira, Mouna, Pradines, Maud, Mardale, Valentina, Gracies, Jean-Michel, Bayle, Nicolas, and Hutin, Emilie

Subjects
WALKING speed, RANGE of motion of joints, RECTUS femoris muscles, MULTIVARIATE analysis, RETROSPECTIVE studies, REGRESSION analysis, SPASTICITY, MUSCLE weakness, LEG, WALKING, CALF muscles, GLUTEAL muscles, DESCRIPTIVE statistics, DATA analysis software, HEMIPLEGIA
Abstract

In spastic paresis, the respective contributions to active function of antagonist hypoextensibility, spasticity, and impaired descending command remain unknown. Objectives: We explored correlations between ambulation speed and coefficients of shortening, spasticity and, weakness for three lower limb extensors. This retrospective study identified 140 subjects with chronic hemiparesis (>6 months since injury) assessed during a single visit with barefoot 10-meter ambulation at comfortable and fast speed, and measurements of passive range of motion (XV1), angle of catch at fast stretch (XV3) and active range of motion (XA) against the resistance of gastrocnemius, rectus femoris, and gluteus maximus. Coefficients of shortening (CSH=[XN-XV1]/XN; XN, normal expected amplitude based on anatomical values), spasticity (CSP=[XV1-XV3]/XV1), and weakness (CWK=[XV1-XA]/XV1) were derived. For each muscle, multivariable analysis explored CSH, CSP, and CWK as potential predictors of ambulation speed. Ambulation speed was 0.62±0.28m/s (mean±SD, comfortable) and 0.84±0.38m/s (fast) and was correlated with CSH and CWK against gastrocnemius (CSH, comfortable, ns; fast, β=−0.20, p=.03; CWK, comfortable, β=−0.21, p=.010; fast, β=−0.21, p =.012), rectus femoris (CSH, comfortable, β=−0.41, p=6E−7; fast, β=−0.43, p=5E−7; CWK, comfortable, β=−0.36, p=5E−5; fast, β=−0.33, p=.0003) and gluteus maximus (CSH, comfortable, β=−0.19, p=.02; fast, β=−0.26, p=.002; CWK, comfortable, β=−0.26, p=.002; fast, β=−0.22, p=.010). Ambulation speed was not correlated with CSP. In chronic hemiparesis, ambulation speed correlates with coefficients of shortening and of weakness in lower limb extensors, but not with their spasticity level. This may encourage therapists to focus treatment primarily on muscle shortening by stretching programs and on impaired descending command by active training. [ABSTRACT FROM AUTHOR]

Published
2022
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29. Worldwide clinician survey on practice patterns and perceptions on use of adjunct therapies following botulinum toxin injection for limb spasticity

Author

Deltombe, Thierry, primary, Schillebeeckx, Fabienne, additional, Ip, Alvin, additional, Schinwelski, Michal, additional, Teixeira, Joao Marten, additional, Ashford, Stephen, additional, Bayle, Nicolas, additional, Chemello, Elena, additional, Jacinto, Jorge, additional, Nayar, Meena, additional, Suzigan, Erika, additional, and Mills, Patricia, additional

Published
2021
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31. Supplemental_Materials – Supplemental material for Ultrasound Structural Changes in Triceps Surae After a 1-Year Daily Self-stretch Program: A Prospective Randomized Controlled Trial in Chronic Hemiparesis

Author

Pradines, Maud, Ghedira, Mouna, Portero, Raphaël, Masson, Ingrid, Marciniak, Christina, Hicklin, Dawn, Hutin, Emilie, Portero, Pierre, Jean-Michel Gracies, and Bayle, Nicolas

Subjects
FOS: Clinical medicine, 110308 Geriatrics and Gerontology, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, Supplemental_Materials for Ultrasound Structural Changes in Triceps Surae After a 1-Year Daily Self-stretch Program: A Prospective Randomized Controlled Trial in Chronic Hemiparesis by Maud Pradines, Mouna Ghedira, Raphaël Portero, Ingrid Masson, Christina Marciniak, Dawn Hicklin, Emilie Hutin, Pierre Portero, Jean-Michel Gracies and Nicolas Bayle in Neurorehabilitation and Neural Repair

Published
2019
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33. Time, touch and temperature affect perceived finger position and ownership in the grasp illusion

Author

Héroux, Martin E., Bayle, Nicolas, Butler, Annie A., and Gandevia, Simon C.

Subjects
body regions, Hand Strength, Touch, Ownership, Temperature, Humans, Proprioception, Illusions, health care economics and organizations, Neuroscience
Abstract

The brain's internal model of the body and the sense of body ownership are fundamental to interaction with the world.It is thought that temporally congruent, repetitive multisensory stimuli are required to elicit a sense of body ownership.Here we investigate the ability of static cutaneous stimuli – passively grasping an artificial finger – to induce body ownership and alter perceived body position; we also investigate how physical characteristics of grasped objects alter these senses.We show that static cutaneous stimuli can alter perceived body position and induce an illusion of ownership and also that signals of temperature, texture and shape of grasped finger‐sized objects influence body ownership.Thus, these aspects of human proprioception can be altered by a single sustained sensory stimulus and by the physical characteristics of held objects.

Published
2017

34. Ultrasound Structural Changes in Triceps Surae After a 1-Year Daily Self-stretch Program: A Prospective Randomized Controlled Trial in Chronic Hemiparesis

Author

Pradines, Maud, primary, Ghedira, Mouna, additional, Portero, Raphaël, additional, Masson, Ingrid, additional, Marciniak, Christina, additional, Hicklin, Dawn, additional, Hutin, Emilie, additional, Portero, Pierre, additional, Gracies, Jean-Michel, additional, and Bayle, Nicolas, additional

Published
2019
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35. Composite active range of motion (CXA) and relationship with active function in upper and lower limb spastic paresis.

Author

Bayle, Nicolas, Maisonobe, Pascal, Raymond, Romain, Balcaitiene, Jovita, and Gracies, Jean-Michel

Subjects
*ARM, *BOTULINUM toxin, *BRAIN tumors, *RANGE of motion of joints, *LEG, *REHABILITATION centers, *RESEARCH funding, *SPASTICITY, *STATISTICS, *STROKE, *DATA analysis, *RANDOMIZED controlled trials, *BLIND experiment, *WALKING speed, *DISEASE complications
Abstract

Objective: The aim of this study is to evaluate a novel composite measure of active range of motion (XA) and determine whether this measure correlates with active function. Design: Post hoc analysis of two randomized, placebo-controlled, double-blind studies with open-label extensions exploring changes in active function with abobotulinumtoxinA. Setting: Tertiary rehabilitation centers in Australia, Europe, and the United States. Subjects: Adults with upper (n = 254) or lower (n = 345) limb spastic paresis following stroke or brain trauma. Interventions: AbobotulinumtoxinA (⩽5 treatment cycles) in the upper or lower limb. Main measures: XA was used to calculate a novel composite measure (CXA), defined as the sum of XA against elbow, wrist, and extrinsic finger flexors (upper limb) or soleus and gastrocnemius muscles (lower limb). Active function was assessed by the Modified Frenchay Scale and 10-m comfortable barefoot walking speed in the upper limb and lower limb, respectively. Correlations between CXA and active function at Weeks 4 and 12 of open-label cycles were explored. Results: CXA and active function were moderately correlated in the upper limb (P < 0.0001–0.0004, r = 0.476–0.636) and weakly correlated in the lower limb (P < 0.0001–0.0284, r = 0.186–0.285) at Weeks 4 and 12 of each open-label cycle. Changes in CXA and active function were weakly correlated only in the upper limb (Cycle 2 Week 12, P = 0.0160, r = 0.213; Cycle 3 Week 4, P = 0.0031, r = 0.296). Across cycles, CXA improvements peaked at Week 4, while functional improvements peaked at Week 12. Conclusion: CXA is a valid measure for functional impairments in spastic paresis. CXA improvements following abobotulinumtoxinA injection correlated with and preceded active functional improvements. [ABSTRACT FROM AUTHOR]

Published
2020
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36. Effects of a 6-month self-rehabilitation programme in addition to botulinum toxin injections and conventional physiotherapy on limitations of patients with spastic hemiparesis following stroke (ADJU-TOX): protocol study for a randomised controlled, investigator blinded study

Author

Bonnyaud, Celine, primary, Gallien, Philippe, additional, Decavel, Pierre, additional, Marque, Philippe, additional, Aymard, Claire, additional, Pellas, Frédéric, additional, Isner, Marie-Eve, additional, Boyer, François Constant, additional, Muller, François, additional, Daviet, Jean-Christophe, additional, Dehail, Patrick, additional, Perrouin-Verbe, Brigitte, additional, Bayle, Nicolas, additional, Coudeyre, Emmanuel, additional, Perennou, Dominic, additional, Laffont, Isabelle, additional, Ropers, Jacques, additional, Domingo-Saidji, Nabila-Yasmine, additional, Bensmail, Djamel, additional, and Roche, Nicolas, additional

Published
2018
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39. Les auteurs

Author

Tiffreau, Vincent, De Boissezon, Xavier, Decavel, Pierre, Giraux, Pascal, Jacquin-Courtois, Sophie, Rémy-Néris, Olivier, Verin, Éric, Amarenco, Gérard, Bayle, Nicolas, Beaudreuil, Johann, Bensoussan, Laurent, Bonan, Isabelle, Bouillet, Benjamin, Boutevillain, Laura, Brochard, Sylvain, Carpentier, Vincent, Chantrelle, Marie, Coudeyre, Emmanuel, Daviet, Jean-Christophe, Dehail, Patrick, Dinomais, Mickael, Doutrellot, Pierre-Louis, Drigny, Joffrey, Ducheine, Clément, Dupeyron, Arnaud, Edouard, Pascal, Garcies, Jean-Michel, Gautheron, Vincent, Genêt, François, Glize, Bertrand, Grémeaux, Vincent, Guinet-Lacoste, Amandine, Hadouiri, Nawale, Hérisson, Christian, Houx, Laetitia, Hupin, David, Isner, Marie-Ève, Laffont, Isabelle, Luauté, Jacques, Marotte, Hubert, Nguyen, Christelle, Obert, Philippe, Ottavy, Maud, Paysant, Jean, Pérennou, Dominic, Perroin-Verbe, Brigitte, Pinelli, Virgile, Poppe, Jean-Baptiste, Prum, Grégoire, Rannou, François, Ribault, Shams, Robain, Gilberte, Roche, Frédéric, Rode, Gilles, Roquet, Marion, Rosin, Maxime, Schnitzler, Alexis, Teng, Maelys, Thoumie, Philippe, Vérin, Éric, Viollet, Émilie, Vuillerot, Carole, and Yelnik, Alain

Published
2021
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