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48 results on '"Bausserman, Linda"'

5. Plateau in body habitus changes and serum lipid abnormalities in HIV-positive women on highly active antiretroviral therapy: a 3.5-year study

Author

Mahajan, Anish P., Tashima, Karen T., Bausserman, Linda L., Flynn, Mary M., and Carpenter, Charles C.J.

Subjects
Body composition, HIV infection -- Drug therapy, Lipid metabolism disorders -- Causes of, Health
Abstract

Most changes in body composition in female HIV patients taking highly active antiretroviral therapy (HAART) occur within the first year and usually stabilize after 2.5 years. However, blood levels of fats and cholesterol become elevated, which is a risk factor for cardiovascular disease.

Published
2001

6. Changes in body habitus and serum lipid abnormalities in HIV-positive women on highly active antiretroviral therapy (HAART)

Author

Dong, Krista L., Bausserman, Linda L., Flynn, Mary M., Dickinson, Brian P., Flanigan, Timothy P., Mileno, Maria D., Tashima, Karen T., and Carpenter, Charles C.J.

Subjects
Antiviral agents -- Adverse and side effects, Fat metabolism, HIV infection -- Drug therapy, Health
Abstract

Highly active antiretroviral therapy (HAART) can have adverse effects on blood lipids that can increase the patient's risk of heart disease. This was seen in a study of 21 women who developed abnormal fat deposits and elevated cholesterol levels.

Published
1999

7. Lipid reactivity to stress: biological and behavioral influences

Author

Stoney, Catherine M., Bausserman, Linda, Niaura, Raymond, Marcus, Bess, and Flynn, Mary

Subjects
Lipid research -- Research, Stress (Psychology) -- Health aspects, Blood pressure -- Research, Health, Psychology and mental health
Abstract

Research about physiological and behavioral influences on lipid concentrations is presented. Responses of atherogenic lipids to stress, diastolic blood pressure, and various stressors are examined.

Published
1999

8. Lipid reactivity to stress: comparison of chronic and acute stress responses in middle-aged airline pilots

Author

Stoney, Catherine M., Matacin, Mala, Niaura, Raymond, and Bausserman, Linda

Subjects
Stress (Psychology) -- Physiological aspects, Lipoproteins -- Research, Middle aged persons -- Psychological aspects, Health, Psychology and mental health
Abstract

Research about how psychological stress affects lipid responsivity for middle-aged people. Physiological response to various stress factors on apoproteins, and low and high density lipoprotein are discussed.

Published
1999

17. Apolipoprotein Quantitation

Author

Herbert, Peter N., Bausserman, Linda L., Henderson, Lloyd O., Heinen, Robert J., LaPiana, Marguerite J., Church, Eve C., Shulman, Richard S., and Peeters, Hubert, editor

Published
1978
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20. Adiponectin and type 2 diabetes in Samoan adults

Author

Dibello, Julia R., Baylin, Ana, Viali, Satupaitea, Tuitele, John, Bausserman, Linda, and Mcgarvey, Stephen T.

Subjects
Americans -- Physiological aspects, Logistic regression -- Usage, Polypeptides -- Health aspects, Type 2 diabetes -- Risk factors, Type 2 diabetes -- Genetic aspects, Biological sciences
Published
2009

21. Interactive effects ofAPOEhaplotype, sex, and exercise on postheparin plasma lipase activities

Author

Seip, Richard L., primary, Zoeller, Robert F., additional, Angelopoulos, Theodore J., additional, Salonia, James, additional, Bilbie, Cherie, additional, Moyna, Niall M., additional, Miles, Mary P., additional, Visich, Paul S., additional, Pescatello, Linda S., additional, Gordon, Paul M., additional, Tsongalis, Gregory J., additional, Bausserman, Linda, additional, and Thompson, Paul D., additional

Published
2011
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32. Hyperhomocysteinemia, hyperfibrinogenemia, and lipoprotein (a) excess in maintenance dialysis patients: a matched case-control study

Author

Bostom, Andrew G., primary, Shemin, Douglas, additional, Lapane, Kate L., additional, Sutherland, Patrice, additional, Nadeau, Marie R., additional, Wilson, Peter W.F., additional, Yoburn, David, additional, Bausserman, Linda, additional, Tofler, Geoffrey, additional, Jacques, Paul F., additional, Selhub, Jacob, additional, and Rosenberg, Irwin H., additional

Published
1996
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37. Interactive effects of APOE haplotype, sex, and exercise on postheparin plasma lipase activities.

Author

Seip, Richard L., Zoeller, Robert F., Angelopoulos, Theodore J., Salonia, James, Bilbie, Cherie, Moyna, Niall M., Miles, Mary P., Visich, Paul S., Pescatello, Linda S., Gordon, Paul M., Tsongalis, Gregory J., Bausserman, Linda, and Thompson, Paul D.

Subjects
APOLIPOPROTEIN E, LIPOPROTEINS, LIPASES, INSULIN, LIPIDS
Abstract

Hepatic lipase (HL) and lipoprotein lipase (LPL) activities (HLA, LPLA) modify lipoproteins and facilitate their binding to hepatic receptors. Apolipoprotein E (APOE) physically interacts with the lipases, and the three common haplotypes of the APOE gene (ε2, ε3, and ε4) yield protein isoforms (E2, E3, and E4, respectively) that are functionally different. Lipase activities themselves differ by sex and exercise training status. The interaction of APOE genotype, exercise training, and sex effects on lipase activities has not been studied. We measured postheparin plasma lipase activities in normolipidemic men and women with the three most common APOE genotypes, which are the haplotype combinations ε2/ε3 (n = 53 ), ε3/ε3 (n = 62), and ε4/ε3 (n = 52), enrolled in 6 mo of aerobic exercise training. These haplotype combinations comprise an estimated 11.6, 62.3, and 21.3% of the population, respectively. Baseline HLA was 35% lower in women than in men (P < 0.0001). In men but not women, HLA was higher in ε2/ε3 group compared with E4/~3 (P = 0.01) and ~3/~3 (P = 0.05). Neither sex nor APOE genotype affected baseline LPLA. Training decreased HLA by 5.2% (P = 0.018) with no APOE effect. The apparent increase in LPLA following exercise was significant and APOE dependent only when corrected for baseline insulin (P < 0.05). Exercise decreased LPLA by 0.8 µmol free fatty acid (FFA)⋅ml-1⋅h-1 (-6%) in ε3/ε3 compared with the combined increases of 6.6% in ε2/ε3 and 12% in ε4/ε3 (P = 0.018 vs. ε3/ε3). However, these differences were statistically significant only after correcting for baseline insulin. We conclude that common APOE genotypes interact with 1) sex to modulate HLA regardless of training status, with ε2/ε3 men demonstrating higher HLA than ε3/ε3 or ε4/ε3 men, and 2) aerobic training to modulate LPLA, regardless of sex, with ε3/ε3 subjects showing a significant decrease compared with an increase in ε2/ε3 and ε3/ε4 after controlling for baseline insulin. [ABSTRACT FROM AUTHOR]

Published
2011
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38. Interaction of the Apoproteins of Very Low Density and High Density Lipoproteins with Synthetic Phospholipids.

Author

Rosseneu, Maryvonne, Soetewey, Frederick, Peeters, Hubert, Bausserman, Linda L., and Herbert, Peter N.

Subjects
LIPOPROTEINS, PHOSPHOLIPIDS, MOLECULAR association, LECITHIN, LIPOSOMES, DENSITY, BIOCHEMISTRY
Abstract

The interaction of synthetic dimyristoyl phosphatidylcholine (lecithin) liposomes with isolated apoC-I and apoC-III proteins from very low density lipoproteins has been studied by micro- calorimetry. Complex formation is a highly exothermal process characterized by a maximal enthalpy of -130 kcal/mol (-544 kJ) apoC-III-1 and -65 kcal mol apoC-I proteins (-272 kJ). The complex composition determined after its isolation by ultracentrifugal flotation agrees with the value derived from the enthalpy binding curves. The binding of a constant amount of dimyristoyl lecithin to apoprotein mixtures containing various proportions of apoA-I and apoC-III failed to demonstrate the existence of any preferential association between the two apoproteins, in contrast with results obtained previously with apoA-I/ apoA-II protein mixtures. Finally the various contributions to the enthalpy of binding such as that arising from an increase in apoprotein helicity have been evaluated. A classification of the apolipoproteins according so their lipid-binding affinity is proposed as: apoA-II [This symbol cannot be presented in ASCII format] apoC-III > apoC-I > apoA-I proteins. [ABSTRACT FROM AUTHOR]

Published
1976
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