Search

Your search keyword '"Baur, Max"' showing total 519 results
Start Over Author "Baur, Max"

Refine your results

more »

more »

more »

more »
519 results on '"Baur, Max"'

5. SNP-Based Analysis of Genetic Substructure in the German Population

Author

Steffens, Michael, Lamina, Claudia, Illig, Thomas, Bettecken, Thomas, Vogler, Rainer, Entz, Patricia, Suk, Eun-Kyung, Toliat, Mohammad Reza, Klopp, Norman, Caliebe, Amke, König, Inke R., Köhler, Karola, Lüdemann, Jan, Lacava, Amalia Diaz, Fimmers, Rolf, Lichtner, Peter, Ziegler, Andreas, Wolf, Andreas, Krawczak, Michael, Nürnberg, Peter, Hampe, Jochen, Schreiber, Stefan, Meitinger, Thomas, Wichmann, H.-Erich, Roeder, Kathryn, Wienker, Thomas F., and Baur, Max P.

Published
2006

10. Preface

Author

Schäfer, Helmut, Amos, Christopher, and Baur, Max P.

Published
2003

17. A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q

Author

Cichon, Sven, Schumacher, Johannes, Müller, Daniel J., Hürter, Martina, Windemuth, Christine, Strauch, Konstantin, Hemmer, Susanne, Schulze, Thomas G., Schmidt-Wolf, Gabriele, Albus, Margot, Borrmann-Hassenbach, Margitta, Franzek, Ernst, Lanczik, Mario, Fritze, Jürgen, Kreiner, Roland, Reuner, Ulrike, Weigelt, Bettina, Minges, Jürgen, Lichtermann, Dirk, Lerer, Bernhard, Kanyas, Kyra, Baur, Max P., Wienker, Thomas F., Maier, Wolfgang, Rietschel, Marcella, Propping, Peter, and Nöthen, Markus M.

Published
2001

19. Nomenclature for Factors of the HLA System 1984

Author

Albert, Ekkehard D., Baur, Max P., Mayr, Wolfgang R., Bertrams, J., Goldmann, S., Grosse-Wilde, H., Opelz, G., Rittner, C., Schendel, D. J., Scholz, S., Wank, R., Albert, Ekkehard D., editor, Baur, Max P., editor, Mayr, Wolfgang R., editor, Bertrams, J., editor, Goldmann, S., editor, Grosse-Wilde, H., editor, Opelz, G., editor, Rittner, C., editor, Schendel, D. J., editor, Scholz, S., editor, and Wank, R., editor

Published
1984
Full Text
View/download PDF

22. Efficient Strategy for Detecting Gene x Gene Joint Action and Its Application in Schizophrenia

Author

Won, Sungho, Kwon, Min-Seok, Baur, Max, Uitterlinden, Andre G, Hofmann, A., Lange, Christoph, Investigators, GROUP, Kahn, René S, Linszen, Don H, van Os, Jim, Wiersma, Durk, Bruggeman, Richard, Mattheisen, Manuel, Cahn, Wiepke, de Haan, Lieuwe, Krabbendam, Lydia, Myin-Germeys, Inez, Park, Suyeon, Park, Changsoon, Kihara, Daisuke, Cichon, Sven, Ophoff, Roel, Nöthen, Markus M, Rietschel, Marcella, Psychiatrie & Neuropsychologie, RS: MHeNs - R2 - Mental Health, MUMC+: MA Psychiatrie (3), MUMC+: Hersen en Zenuw Centrum (3), Adult Psychiatry, Amsterdam Neuroscience, Internal Medicine, and Epidemiology

Subjects
Linkage disequilibrium, Epidemiology, Genome-wide association study, genetics [Genetic Loci], Computational biology, Biology, minor allele frequency, methods [Genome-Wide Association Study], Polymorphism, Single Nucleotide, Statistical power, Gene Frequency, Genetic model, Humans, genetics [Schizophrenia], Genetic Predisposition to Disease, ddc:610, genetics [Genome, Human], genetics [Genetic Predisposition to Disease], Gene, Allele frequency, Genetics (clinical), Genetic association, Genetics, Models, Genetic, Genome, Human, Hardy-Weinberg disequilibrium, Epistasis, Genetic, gene x gene joint action, Minor allele frequency, Genes, Genetic Loci, Case-Control Studies, genetics [Polymorphism, Single Nucleotide], Schizophrenia, genetics [Gene Frequency], genetics [Epistasis, Genetic], genetics [Linkage Disequilibrium], linkage disequilibrium, Genome-Wide Association Study
Abstract

We propose a new approach to detect gene ? gene joint action in genome-wide association studies (GWASs) for case-control designs. This approach offers an exhaustive search for all two-way joint action (including, as a special case, single gene action) that is computationally feasible at the genome-wide level and has reasonable statistical power under most genetic models. We found that the presence of any gene ? gene joint action may imply differences in three types of genetic components: the minor allele frequencies and the amounts of Hardy-Weinberg disequilibrium may differ between cases and controls, and between the two genetic loci the degree of linkage disequilibrium may differ between cases and controls. Using Fisher's method, it is possible to combine the different sources of genetic information in an overall test for detecting gene ? gene joint action. The proposed statistical analysis is efficient and its simplicity makes it applicable to GWASs. In the current study, we applied the proposed approach to a GWAS on schizophrenia and found several potential gene ? gene interactions. Our application illustrates the practical advantage of the proposed method. ? 2013

Published
2014
Full Text
View/download PDF

40. Transmission of Vitamin D Receptor Haplotypes Differs Among Subsets of German Type 1 Diabetes Mellitus Families

Author

PANI, MICHAEL A., KNAPP, MICHAEL, DONNER, HORST, SIEGMUND, THORSTEN, BAUR, MAX P., USADEL, KLAUS H., and BADENHOOP, KLAUS

Subjects
Vitamin D -- Physiological aspects, Type 1 diabetes -- Health aspects, Health
Abstract

Vitamin D experimentally influences type 1 diabetes mellitus pathogenesis via its nuclear receptor (VDR). VDR haplotypes were recently reported to be associated with susceptibility to type 1 diabetes in Germans [...]

Published
2000

45. GENESTAT : an information portal for design and analysis of genetic association studies

Author

Ripatti, Samuli, Becker, Tim, Bickeboeller, Heike, Dominicus, Annica, Fischer, Christine, Humphreys, Keith, Jonasdottir, Gudrun, Moreau, Yves, Olsson, Marita, Ploner, Alexander, Sheehan, Nuala, Van Steen, Kristel, Baur, Max, van Duijn, Cornelia, Palmgren, Juni, Ripatti, Samuli, Becker, Tim, Bickeboeller, Heike, Dominicus, Annica, Fischer, Christine, Humphreys, Keith, Jonasdottir, Gudrun, Moreau, Yves, Olsson, Marita, Ploner, Alexander, Sheehan, Nuala, Van Steen, Kristel, Baur, Max, van Duijn, Cornelia, and Palmgren, Juni

Abstract

We present the rationale, the background and the structure for version 2.0 of the GENESTAT information portal (www.genestat.org) for statistical genetics. The fast methodological advances, coupled with a range of standalone software, makes it difficult for expert as well as non-expert users to orientate when designing and analysing their genetic studies. The ultimate ambition of GENESTAT is to guide on statistical methodology related to the broad spectrum of research in genetic epidemiology. GENESTAT 2.0 focuses on genetic association studies. Each entry provides a summary of a topic and gives links to key papers, websites and software. The flexibility of the internet is utilised for cross-referencing and for open editing. This paper gives an overview of GENESTAT and gives short introductions to the current main topics in GENESTAT, with additional entries on the website. Methods and software developers are invited to contribute to the portal, which is powered by a Wikipedia-type engine and allows easy additions and editing., authorCount :15

Published
2009
Full Text
View/download PDF

46. Genestat: An information portal for design and analysis of genetic association studies

Author

Ripatti, Samuli, Becker, Tim, Bickeböller, Heike, Dominicus, Annica, Fischer, Christine, Humphreys, Keith, Jonasdottir, Gudrun, Moreau, Yves, Olsson, Marita, Ploner, Alexander, Sheehan, Nuala, van Steen, Kristel, Baur, Max, van Duijn, Cornelia, Palmgren, Juni, Ripatti, Samuli, Becker, Tim, Bickeböller, Heike, Dominicus, Annica, Fischer, Christine, Humphreys, Keith, Jonasdottir, Gudrun, Moreau, Yves, Olsson, Marita, Ploner, Alexander, Sheehan, Nuala, van Steen, Kristel, Baur, Max, van Duijn, Cornelia, and Palmgren, Juni

Published
2008

47. ISFG: Recommendations on biostatistics in paternity testing

Author

Gjertson, David W, Brenner, Charles H, Baur, Max P, Carracedo, Angel, Guidet, Francois, Luque, Juan A, Lessig, Rüdiger, Mayr, Wolfgang R, Pascali, Vince L, Prinz, Mechthild, Schneider, Peter M, Morling, Niels, Gjertson, David W, Brenner, Charles H, Baur, Max P, Carracedo, Angel, Guidet, Francois, Luque, Juan A, Lessig, Rüdiger, Mayr, Wolfgang R, Pascali, Vince L, Prinz, Mechthild, Schneider, Peter M, and Morling, Niels

Abstract

Udgivelsesdato: 2007-Dec, The Paternity Testing Commission (PTC) of the International Society for Forensic Genetics has taken up the task of establishing the biostatistical recommendations in accordance with the ISO 17025 standards and a previous set of ISFG recommendations specific to the genetic investigations in paternity cases. In the initial set, the PTC recommended that biostatistical evaluations of paternity are based on a likelihood ratio principle - yielding the paternity index, PI. Here, we have made five supplementary biostatistical recommendations. The first recommendation clarifies and defines basic concepts of genetic hypotheses and calculation concerns needed to produce valid PIs. The second and third recommendations address issues associated with population genetics (allele probabilities, Y-chromosome markers, mtDNA, and population substructuring) and special circumstances (deficiency/reconstruction and immigration cases), respectively. The fourth recommendation considers strategies regarding genetic evidence against paternity. The fifth recommendation covers necessary documentation, reporting details and assumptions underlying calculations. The PTC strongly suggests that these recommendations should be adopted by all laboratories involved in paternity testing as the basis for their biostatistical analysis.

Published
2007

48. P4-084: Genome-wide association study using cerebrospinal fluid biomarkers beta-amyloid-42 and pTau181 in German samples of Alzheimer's disease

Author

Ramirez, Alfredo, primary, Herold, Christine, additional, Lewczuk, Piotr, additional, Lacour, André, additional, Drichel, Dmitriy, additional, Schürmann, Britta, additional, Kornhuber, Johannes, additional, Peters, Oliver, additional, Heun, Reiner, additional, Hampel, Harald, additional, Frölich, Lutz, additional, Hüll, Michael, additional, Hoffmann, Per, additional, Vogt, Stefani, additional, Kölsch, Heike, additional, Heneka, Michael, additional, Alferink, Judith, additional, Rüther, Eckart, additional, Wiltfang, Jens, additional, Dichgans, Martin, additional, Baur, Max, additional, Jessen, Frank, additional, Maier, Wolfgang, additional, Becker, Tim, additional, and Nöthen, Markus, additional

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results