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852 results on '"Baum, Bruce J."'

7. Supplementary Table 1, Supplementary Figures 1 through 9, and Supplementary Materials and Methods from Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation

Author

Marmary, Yitzhak, primary, Adar, Revital, primary, Gaska, Svetlana, primary, Wygoda, Annette, primary, Maly, Alexander, primary, Cohen, Jonathan, primary, Eliashar, Ron, primary, Mizrachi, Lina, primary, Orfaig-Geva, Carmit, primary, Baum, Bruce J., primary, Rose-John, Stefan, primary, Galun, Eithan, primary, and Axelrod, Jonathan H., primary

Published
2023
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8. Xerostomia

Author

Cotrim, Ana P., Zheng, Changyu, Baum, Bruce J., Sonis, Stephen T., editor, and Keefe, Dorothy M., editor

Published
2013
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13. Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

Author

Baum, Bruce J., Alevizos, Ilias, Zheng, Changyu, Cotrim, Ana P., Liu, Shuying, McCullagh, Linda, Goldsmith, Corinne M., Burbelo, Peter D., Citrin, Deborah E., Mitchell, James B., Nottingham, Liesl K., Rudy, Susan F., Van Waes, Carter, Whatley, Millie A., Brahim, Jaime S., Chiorini, John A., Danielides, Stamatina, Turner, R. James, Patronas, Nicholas J., Chen, Clara C., Nikolov, Nikolay P., and Illei, Gabor G.

Published
2012

15. Gene Therapy of Salivary Diseases

Author

Baum, Bruce J., primary, Afione, Sandra, additional, Chiorini, John A., additional, Cotrim, Ana P., additional, Goldsmith, Corinne M., additional, and Zheng, Changyu, additional

Published
2016
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16. Clinical Research, Dental Education, and the NIH Clinical Research Training Program.

Author

Baum, Bruce J. and Davis, Clifford

Abstract

An expert panel, convened by the National Institutes of Health to address concerns about the future of clinical research, describes a training program at the National Institutes of Health that also included dental students. Possible reasons for low application rates among dental students are ascribed to inadequate dissemination of information, high student indebtedness, and low interest in clinical research. (CH)

Published
1998

18. Ahead of her time: The multidimensional impact of Marie Ussing Nylen.

Author

Robey, Pamela Gehron and Baum, Bruce J.

Subjects
*TEETH, *CONNECTIVE tissues, *EXECUTIVES, *HUMANISM, *ELECTRON microscopy, *BONE regeneration, *MINERALS, *DENTAL research
Abstract

Marie Ussing Nylen was a trail blazing scientist and administrative leader at the US National Institutes of Health. She accomplished this when it was extremely difficult for a woman to do so. She was also a whole person ‐ a wife, mother, and talented athlete, that is, a well‐rounded person by any definition. She was a gift to dental and oral science, as well as to those fortunate enough to know and work with her. [ABSTRACT FROM AUTHOR]

Published
2023
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23. Has Modern Biology Entered the Mouth? The Clinical Impact of Biological Research.

Author

Baum, Bruce J.

Abstract

Three areas of biological research that are beginning to have an impact on clinical medicine are examined, including molecular biology, cell biology, and biotechnology. It is concluded that oral biologists and educators must work cooperatively to bring rapid biological and biomedical advances into dental training in a meaningful way. (MSE)

Published
1991

35. Inadequate training in the biological sciences and medicine for dental students: an impending crisis for dentistry

Author

Baum, Bruce J.

Subjects
Biology -- Study and teaching, Dental students -- Training, Dentists -- Practice, Medical sciences -- Study and teaching, Patients -- Care and treatment, Patients -- Management, Company business management, Health
Abstract

The importance of providing proper training to dental students in medicine and biological sciences, to help the dentists take efficient care of patients who are undergoing other medical treatments, is discussed.

Published
2007

36. Xerostomia

Author

Cotrim, Ana P., primary, Zheng, Changyu, additional, and Baum, Bruce J., additional

Published
2012
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37. Gene Therapy of Salivary Diseases

Author

Baum, Bruce J., primary, Adriaansen, Janik, additional, Cotrim, Ana P., additional, Goldsmith, Corinne M., additional, Perez, Paola, additional, Qi, Senrong, additional, Rowzee, Anne M., additional, and Zheng, Changyu, additional

Published
2010
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39. The impact of gene therapy on dentistry: a revisiting after six years

Author

Baum, Bruce J., Kok, Marc, Tran, Simon D., and Yamano, Seiichi

Subjects
Gene therapy -- Research, Mouth diseases -- Care and treatment, Health
Abstract

In dentistry, genes could be introduced into bone, salivary glands, keratinocytes, and cancer cells. Although gene therapy is relatively primitive in 2002, a wide range of gene therapy options should be available by 2015.

Published
2002

43. The impact of tissue engineering on dentistry

Author

Baum, Bruce J. and Mooney, David J.

Subjects
Artificial organs -- Health aspects, Dentistry -- Innovations, Health
Abstract

Tissue engineering will have a substantial impact on dentistry. Tissue engineering involves growing biological tissues in the laboratory, or giving patients drugs that stimulate tissue formation in the body. Skin, connective tissues, and even bone can be produced in this way. Dental applications include periodontal disease, bone grafts, cavities, and lost teeth. Gene therapy could be used to stimulate saliva production in patients with Sjogren's disease or those who have received radiation therapy for head and neck cancer. Drugs could be used to stimulate wound healing inside the mouth.

Published
2000

44. Longitudinal Influence of Age, Menopause, Hormone Replacement Therapy, and Other Medications on Parotid Flow Rates in Healthy Women

Author

Ghezzi, Elisa M., Wagner-Lange, Leslie A., Schork, M. Anthony, Metter, E. Jeffrey, Baum, Bruce J., Streckfus, Charles F., and Ship, Jonathan A.

Subjects
Aging -- Physiological aspects, Salivary glands -- Diseases, Drugs -- Adverse and side effects, Health, Seniors
Abstract

Background. Recent investigations have demonstrated that parotid salivary dysfunction is not a normal process of aging, but may be the consequence of systemic conditions and their treatment, including medications and menopause. The purpose of this study was to assess longitudinally the influence of age, menopausal status, hormone replacement therapy, and other medications on stimulated parotid flow rates (SPFRs) in healthy women. Methods. Medical diagnoses, menopausal status, medication utilization, and 2% citric acid stimulated parotid salivas were collected from 396 women, aged 21 to 96 years, from the Baltimore Longitudinal Study of Aging (National Institute on Aging, National Institutes of Health) over a 17-year span by three investigators. Results. There was no overall longitudinal effect of time on SPFR. Age at first visit was a significant predictor of a decrease in SPFR when adjusted for time and xerostomic medications. However, the deleterious effect of taking one xerostomic medication was equivalent to approximately 14 years of aging. Menopausal status and hormone replacement therapy were not consistently associated with diminished SPFR. Conclusions. These results suggest that menopause and hormone replacement therapy are not associated with parotid salivary dysfunction. Aging may have a statistically significant yet small deleterious influence on SPFR; however, the adverse influence of xerostomic medications is much larger.

Published
2000

47. Aiming high

Author

Baum, Bruce J. and Scully, Crispian

Published
2009

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