234 results on '"Baukrowitz, Thomas"'
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2. Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels
3. Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
4. Gain-of-function mutations in KCNK3 cause a developmental disorder with sleep apnea
5. An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier
6. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.
7. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2
8. Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
9. From head to tail - Atomistic mechanism of long-range coupling from the cytosolic sensor domain to the selectivity filter in TREK K2Pchannels
10. Functional Conversion between A-Type and Delayed Rectifier K + Channels by Membrane Lipids
11. PIP$_2$ and PIP as Determinants for ATP Inhibition of K$_{ATP}$ Channels
12. Two Functionally Distinct Subsites for the Binding of Internal Blockers to the Pore of Voltage-Activated K + Channels
13. Use-Dependent Blockers and Exit Rate of the Last Ion from the Multi-Ion Pore of a K$^+$ Channel
14. Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation
15. Sodium permeable and “hypersensitive” TREK‐1 channels cause ventricular tachycardia
16. KCNJ10 gene mutations causing EAST syndrome (epilepsy, ataxia, sensorineural deafness, and tubulopathy) disrupt channel function
17. The versatile regulation of K2P channels by polyanionic lipids of the phosphoinositide and fatty acid metabolism
18. Side pockets provide the basis for a new mechanism of Kv channel–specific inhibition
19. Defective X-gating caused byde novogain-of-function mutations inKCNK3underlies a developmental disorder with sleep apnea
20. The versatile regulation of K2P channels by polyanionic lipids of the phosphoinositide (PIP2) and fatty acid metabolism (LC-CoA)
21. Identification of the muscarinic pathway underlying cessation of sleep-related burst activity in rat thalamocortical relay neurons
22. The pore structure and gating mechanism of K2P channels
23. RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels
24. Norfluoxetine inhibits TREK-2 K2P channels by multiple mechanisms including state-independent effects on the selectivity filter gate
25. Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel
26. Structural Basis for Gating of the Two-Pore Domain K+ (K2P) Channels TASK-1 and TALK-2
27. Molecular basis of inward rectification: polyamine interaction sites located by combined channel and ligand mutagenesis
28. Functional conversion between A-type and delayed rectifier [K.sup.+] channels by membrane lipids
29. Inward rectification in KATP channels: a pH switch in the pore
30. Multiple Mechanisms Underlie State-Independent Inhibitory Effects of Norfluoxetine on TREK-2 K2P Channels
31. Characterisation of the Versatile Gating Behaviour in Talk-2 K2P Channels
32. Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel
33. Random mutagenesis screening indicates the absence of a separate H+-sensor in the pH-sensitive Kir channels
34. Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels
35. Two functionally distinct subsites for the binding of internal blockers to the pore of voltage-activated K+ channels
36. The inward rectification mechanism of the HERG cardiac potassium channel
37. Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ Channel
38. The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels
39. A pharmacological master key mechanism that unlocks the selectivity filter gate in K + channels
40. A Pharmacological Masterkey Mechanism to Unlock the Selectivity Filter Gate in K+ Channels
41. Gain-of-function mutations in KCNK3cause a developmental disorder with sleep apnea
42. Author response: The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels
43. The VAMP‐associated protein VAPB is required for cardiac and neuronal pacemaker channel function
44. Erratum: The pore structure and gating mechanism of K2P channels
45. Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel
46. Silver as a Probe of Selectivity Filter Gating in TREK-1 K2P Channels
47. From head to tail—atomistic mechanism of long-range coupling from the cytosolic sensor domain to the selectivity filter in TREK K2Pchannels
48. Dynamic interplay of the proximal C-terminus and selectivity filter reveals gating and pharmacological modulation mechanisms in TREK K2P channels
49. Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states
50. Liposome-Based in Vitro Biosynthesis of Two-Pore Domain Potassium Channels for Functional Studies
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