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2. Ticarcillin-Clavulanate Therapy for Infections With Ticarcillin-Resistant Microorganisms

Author

Baucom W, Michael S. Gelfand, and Lawson Rd

Subjects
Adult, Male, Penicillin Resistance, Penicillins, Serious infection, Microbiology, Clavulanic Acids, Potassium Clavulanate, Gram-Negative Bacteria, polycyclic compounds, medicine, Humans, Ticarcillin, heterocyclic compounds, Prospective Studies, Ticarcillin/clavulanic acid, Aged, Aged, 80 and over, business.industry, Bacterial Infections, General Medicine, Middle Aged, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, bacteria, Ticarcillin Disodium, Drug Therapy, Combination, Female, business, medicine.drug
Abstract

In a prospective study, 46 episodes of serious infection with ticarcillin-resistant microorganisms were treated with the combination ticarcillin disodium and clavulanate potassium (Timentin). Clinical cure was achieved in 35 of the 46 episodes (76%), and microbiologic eradication was achieved in 30 (65%). We found no development of resistance to ticarcillin-clavulanate and observed no serious side effects.

Published
1989

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