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O trabalho tem como objetivo investigar as escolhas teórico-metodológicas e as abordagens de pesquisa de um periódico na área de avaliação educacional. Trata-se de uma pesquisa documental, descritiva e de abordagem mista. Foi coletado um total de 88 trabalhos dispostos em 11 edições/volumes da revista IMPA ao longo do recorte temporal de 2020 a 2024, os quais foram selecionados para o processo de análise. Os dados foram apresentados em forma de quadro descritivo e distribuídos a partir de frequência relativa (%) e absoluta (n). Os resultados indicaram a predominância da abordagem de pesquisa qualitativa, além de bibliografia/documentos, documentos e questionário como as técnicas mais requisitadas no processo de obtenção dos dados.

BackgroundBedside ultrasonography, also known as point-of-care ultrasound (PoCUS), is a promising technological tool that enhances clinical assessment, enriching diagnostic capabilities and clinical reasoning. Its use in nursing spans various patient populations and health care settings, providing nurses with a valuable health assessment tool to improve care quality and patient safety. Despite its growing integration into clinical practice, PoCUS training has mainly focused on physicians, leaving a gap for trained nurses who demonstrate similar proficiency in conducting scans and interpreting images. Previous research highlights the value of digital tools in PoCUS training, showing their role in improving professionals’ and students’ knowledge, image interpretation skills, and clinical acumen. ObjectiveThis study aimed to (1) establish an assessment instrument gauging nurses’ competency milestones in PoCUS and evaluate its content and appearance validity, (2) develop a series of 5 educational videos focused on PoCUS and assess their content and appearance validity, and (3) construct an online learning environment tailored to nurses’ PoCUS training needs and evaluate its content and appearance validity. MethodsWe will conduct a methodological study of technological production guided by Rogers’ diffusion of innovations theory. Subproject 1 will design and validate a comprehensive assessment tool for evaluating nurses’ competency milestones in PoCUS use. For this purpose, a scoping review will be conducted. The review will be based on JBI Collaboration guidelines and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extended for Scoping Reviews (PRISMA-ScR) checklist. Subproject 2 involves an evaluation of content and appearance validity for a series of 5 educational videos on PoCUS, designed specifically for nurses about applying peripherally inserted central catheter lines, inserting nasogastric feeding tubes, assessing gastric residual volume, assessing pressure injuries and soft tissue conditions, and assessing muscle mass to monitor patient nutritional status. In subproject 3, a comprehensive online learning environment dedicated to PoCUS training for nurses will be developed and validated. The launch of an online learning environment represents a cornerstone of our dissemination strategy, scheduled to coincide with the inaugural Brazilian PoCUS symposium for nurses, an event organized by the project members. This platform will serve as a pivotal resource for continuous learning and professional development. ResultsSubproject 1 will start in the second half of 2024 and is expected to be completed by mid-2025. Subproject 2 is currently ongoing and is expected to be completed in early 2026. Subproject 3 is set to begin in early 2025 and is planned to be completed by 2026. ConclusionsThrough these concerted efforts, the project aims to bridge the existing gap in PoCUS training for nurses, thereby fostering their proficiency and enhancing patient care outcomes. International Registered Report Identifier (IRRID)PRR1-10.2196/58030

Na primeira década do século XXI, o Povo indígena Truká através de um processo de retomada, conseguiu reaver todo o território da Ilha da Assunção (Cabrobó/PE) das mãos dos posseiros, esse contexto constitui movimentos de reafirmação identitária que envolvem diversas questões políticas, sociais e culturais contemporâneas. A construção do presente texto visa analisar a relação dos Truká com a terra após a reconquista de seus territórios. A pesquisa objetiva compreender as vivências Truká e suas relações identitárias pós retomadas e foi desenvolvida com base na análise do corpus e a partir da categorização, distribuição de códigos, inferência, descrição e interpretação dos dados, dentre as narrativas das lutas, retomadas, cultura, sentimentos de pertencimento e identidade das lideranças indígenas locais. A análise dos códigos e documentações por meio do gerenciador evidenciou em 30 entrevistas realizadas, 11 categorias e 1.304 códigos, destacando-se as ações coletivas, relação com a terra, pertencimento, tradições, cultura e saberes, estabelecendo uma ligação entre as tradições e coletividades, construídas e em construção, que representam os eixos da identidade Truká na atualidade. A escola Truká é resguarda a cultura e fortalece a identidade Truká com o território garantindo a sobrevivência político-social presente nas mobilizações do povo.

ABSTRACT: Leptospirosis is a zoonotic disease that must be studied on the One Health point of view. It is possible that there are particularities in the epidemiology of leptospirosis in Caatinga biome, where the environment is often unfavorable and challenges the adaptability of Leptospira spp. Overall, 100 dogs (47 shelter and 53 stray dogs) selected based on sampling calculation were used to evaluate the Leptospira spp. seroprevalence and associated factors. The microscopic agglutination test (MAT) was applied to detect anti-Leptospira spp. antibodies (cut-off titer 50). Risk factors were identified using the robust Poisson regression analysis. Twenty-four animals (24%; 95% CI = 15.6% - 32.4%) were seroreactive, antibody titers ranged from 50 to 200, and the reacting serogroups were Ballum (17%), Autumnalis (6%) and Djasiman (1%). The factors/categories associated with seropositivity were the environment where the animal stay/soil (prevalence ratio [PR] = 6.03; 95% CI for PR: 1.86 - 7.69; P < 0.001) and access to polluted water/yes (PR = 3.79; 95% CI for PR: 1.85 - 24.22; P = 0.011). The results suggested leptospirosis as a concern in the One Health context in stray and shelter dogs from the Caatinga biome despite the adverse conditions of this biome for the survive of Leptospira spp. on the environment. Moreover, despite being social and government issues, factors such as environment where the animal stay (soil) and access to polluted water must be carefully deemed and corrected to avoid the transmission of leptospires to animals and humans.

BACKGROUND AND OBJECTIVES: This research stems from the scarcity of official data regarding the homeless population and the challenging realities faced by this group, such as social invisibility and precarious access to healthcare services. The main objective is to conduct a narrative review to understand the interconnection between chronic pain (CP), depression, and sleep disorders in this population, identifying key factors that play a role in these conditions. CONTENTS: The study employs a qualitative narrative review, conducting a comprehensive search in the Web of Science and Scopus databases without temporal restrictions. It utilizes English descriptors related to homelessness, depression, and sleep disorders. Globally, over 100 million people are homeless, with Brazil particularly affected by this phenomenon due to the economic crisis. The prevalence of CP in this group is linked to precarious living conditions, discrimination, and exposure to violence. The impairment of sleep quality, depression, and the bidirectional relationship between CP and depressive disorders are highlighted. Social vulnerability, lack of access to health resources, and the adversities of living conditions contribute to the complexity of challenges faced by the homeless population, negatively impacting overall health. CONCLUSION: Individuals experiencing homelessness face increased vulnerability to injuries, CP, depression, and sleep disorders. The bidirectional relationship between pain and depression is exacerbated by the adversities they endure. It is crucial to implement specific and effective health policies to improve living conditions, promoting equity and social justice for this vulnerable and marginalized population.

ABSTRACT Objectives: to identify in the literature the main nursing diagnoses according to the NANDA-I diagnostic classification for people hospitalized with heart failure. Methods: an integrative literature review, carried out in February 2019 and updated in July 2023, in the MEDLINE via PubMed, LILACS, SciELO and CINAHL databases. Given the use of acronym PEO, studies without a time cut in Portuguese, English and Spanish were included. Descriptive analysis was carried out to present the identified information. Results: analysis of 27 articles identified 24 nursing diagnoses, with emphasis on Decreased Cardiac Output, Excessive Fluid Volume, Decreased Activity Tolerance and Fatigue. Final Considerations: evidence can contribute to better diagnostic decisions centered on people with heart failure in search of more assertive health results and have the potential to support future studies on a possible syndromic pattern in this population.

ABSTRACT Objective: to assess validity evidence of an educational video on safe sexual activity after acute coronary syndrome. Method: study in three phases: video development; content validity analysis by 11 experts; and analysis of validity based on response processes by seven people with coronary disease. The content validity ratio (CVR) was calculated with critical values for the second phase of 0.63 and for the third of 1.0. Results: the video addressed the importance of resuming sexual activity and positions that consume less energy, clinical warning signs, the importance of adhering to treatment and a welcoming environment for sexual practice. A CVR above the critical value was obtained with a total of 4 minutes and 41 seconds. Conclusion: the educational video brings together adequate content validity evidence and can be used as a tool for patients after acute coronary syndrome.

Resumo Objetivo Fornecer uma visão geral da prevalência de diagnósticos de enfermagem em diferentes populações de pacientes e cenários de cuidado à saúde, e sobre os métodos de identificação dos diagnósticos de enfermagem. Métodos Revisão descritiva com aplicação de método sistemático de acordo com as diretrizes do Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Foram incluídos estudos das bases de dados Medline e CINAHL publicados entre janeiro de 2007 e janeiro de 2020, que relataram a prevalência de diagnósticos de enfermagem, independentemente da população e do cenário (n=1839). Resultados Após a triagem, foram incluídos 328 artigos para análise. Foram identificadas 20 populações diferentes de pacientes com suas respectivas prevalências de diagnósticos de enfermagem. A maioria dos estudos foi realizada em ambientes hospitalares (por exemplo, unidades de terapia intensiva e cirúrgicas). A Classificação da NANDA International foi uma linguagem padronizada de enfermagem amplamente utilizada e o Risco de infecção foi o diagnóstico mais frequentemente identificado. Foram identificadas diversas lacunas quanto aos métodos utilizados nos artigos. Conclusão Foram identificados os diagnósticos de enfermagem mais prevalentes nas diferentes populações de pacientes. Além disso, foram sumarizados os diagnósticos de enfermagem das cinco linguagens padronizadas de enfermagem reconhecidas pela American Nurses Association e identificados avanços, lacunas e uma chamada para ação.

There is growing interest in using cannabinoids across various clinical scenarios, including pain medicine, leading to the disregard of regulatory protocols in some countries. Legislation has been implemented in Brazil, specifically in the state of São Paulo, permitting the distribution of cannabinoid products by health authorities for clinical purposes, free of charge for patients, upon professional prescription. Thus, it is imperative to assess the existing evidence regarding the efficacy and safety of these products in pain management. In light of this, the São Paulo State Society of Anesthesiology (SAESP) established a task force to conduct a narrative review on the topic using the Delphi method, requiring a minimum agreement of 60% among panelists. The study concluded that cannabinoid products could potentially serve as adjuncts in pain management but stressed the importance of judicious prescription. Nevertheless, this review advises against their use for acute pain and cancer-related pain. In other clinical scenarios, established treatments should take precedence, particularly when clinical protocols are available, such as in neuropathic pain. Only patients exhibiting poor therapeutic responses to established protocols or demonstrating intolerance to recommended management may be considered as potential candidates for cannabinoids, which should be prescribed by physicians experienced in handling these substances. Special attention should be given to individual patient characteristics and the likelihood of drug interactions.

The aim of this paper is to analyse the concept of testimony and to promote reflections that support the understanding of this linguistic act through the lens of the concept of Zeitzeuge/Zeitzeugenschaft. Our analyses aim to observe how the value of the witness is constructed in the paratext of Ruth Klüger’s work weiter leben, from the German original and its paperback version (1992; 1997) to the later versions in French (1997), English (2001) and Portuguese (2005). In addition to drawing on the work of various scholars on the notion of testimony, this paper is based on the principles of dialogic discourse theory in conjunction with the category of paratext proposed by Genette (2009). Among other things, this study shows how discourse in the testimony is directly influenced by the valorisation of the role of the witness, which in the case analysed leads to different ways of reading the “same work”.

Background: This study aimed to investigate the analgesic impact of S(+)-ketamine on pain behavior and synovial inflammation in an osteoarthritis (OA) model. Methods: Animals were grouped as follows: OA-Saline (n = 24) and OA-Ketamine (n = 24), OA induced via intra-articular sodium monoiodoacetate (MIA); a Non-OA group (n = 24) served as the control. On the 7th day post OA induction, animals received either saline or S(+)-ketamine (0.5 mg.kg−1). Behavioral and histopathological assessments were conducted up to day 28. Results: S(+)-ketamine reduced allodynia from day 7 to 28 and hyperalgesia from day 10 to 28. It notably alleviated weight distribution deficits from day 10 until the end of the study. Significant walking improvement was observed on day 14 in S(+)-ketamine-treated rats. Starting on day 14, OA groups showed grip force decline, which was countered by S(+)-ketamine on day 21. However, S(+)-ketamine did not diminish synovial inflammation. Conclusion: Low Intra-articular (IA) doses of S(+)-ketamine reduced MIA-induced OA pain but did not reverse synovial histopathological changes. IRB approval number: 23115 012030/2009-05.

Este estudo buscou investigar a aplicabilidade da talidomida no manejo da dor na endometriose induzida em animais. Foi realizada uma revisão de escopo confeccionada e organizada seguindo o método Joanna Briggs Institute, além de seguir os padrões do PRISMA – ScR. Foram feitas pesquisas em seis bases de dados eletrônicas associando descritores e as palavras chaves, por meio de busca booleana correspondente aos blocos conceituais voltados para recuperação de estudos sobre endometriose, dor, manejo da dor e talidomida. Os países dos estudos foram: Irã (n =1, 50%) e Turquia (n = 1, 50%). Todos os artigos (n = 2; 100%) foram publicados em inglês. Quanto ao ano de publicação, observa-se que todos foram publicados nos últimos 10 anos. Nos estudos onde há comparação entre talidomida e placebo observa-se que há uma alta resposta associada com a redução de fatores inflamatórios impactando diretamente na melhora clínica dos quadros álgicos com benefícios que levam até a redução de fatores de crescimento e controle do ciclo das metaloproteinases (MPP). A busca dos estudos mostrou a atividade antiangiogênica e anti-inflamatória do fármaco, o que sugere uma opção para ser utilizada como tratamento de dor, contudo poucas literaturas estão disponíveis com talidomida.

Objective: to evaluate the evidence of validity of the internal structure and reliability of the Brazilian version of the Smoking Cessation Counseling instrument Method: psychometric study of confirmatory factor analysis and reliability carried out on 250 nurses in clinical practice. For the analysis of the convergent validity of the factor model, Average Variance Extracted values were calculated, and discriminant analysis was carried out using the Fornell-Larcker criterion. Reliability was examined using Cronbach’s alpha coefficient and composite reliability Results: it was necessary to exclude seven items from the Advanced Counseling domain and one item from the Basic Counseling domain in order to properly obtain the Average Variance Extracted values and the Fornell-Larcker criterion. The composite reliability ranged from 0.76 to 0.86 and the overall Cronbach`s alpha coefficient was 0.86, ranging from 0.53 to 0.84 depending on the domain assessed. The final version of the instrument was made up of 16 items divided into 4 domains Conclusion: the Brazilian version of Smoking Cessation Counseling obtained adequate psychometric evidence of validity and reliability. Further studies are needed to refine the instrument.

Summary: Background: Patients admitted to the Intensive Care Unit (ICU) are at greater risk of developing nosocomial infections due to their investigations, treatment and changes in the immune system. One of the most prevalent nosocomial infections is respiratory tract infection, such as hospital acquired pneumonia and ventilator-associated pneumonia (VAP). The bacteria commonly found in the oral cavity in the hospital environment are Streptococcus viridians, Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus spp., and Klebsiella pneumoniae. There is a need to test and define appropriate standard protocols for oral hygiene in patients undergoing mechanical ventilation in ICUs through the intervention of a dental specialist, preventing the proliferation of microorganisms into the respiratory tract, thus reducing hospitalization time, the use of antibiotics, and increased morbidity/mortality. Objective: This study aimed to evaluate the effectiveness of dental brushing in the reduction of the pathogenic buccal microbiota associated with mechanical ventilation in patients admitted to the Evangelical Hospital from Londrina, Paraná, Brazil. Methodology: The sample consisted of 90 patients (of both sexes), mean age of 65 years, under mechanical ventilation by orotracheal tube and tracheostomized patients, without suspected or confirmed diagnosis of pneumonia. Patients were randomized ∗∗∗ Results: Results showed that oral hygiene using a toothbrush by suction, with chlorhexidine gel 0.12% (Group B), was more effective than conventional hygiene using gauze soaked with chlorhexidine 0.12% (Group A) in reducing pathogenic buccal microbiota. Conclusions: There was a reduction of the pathogenic buccal microbiota in mechanically ventilated patients receiving oral hygiene using a toothbrush by suction with chlorhexidine gel 0.12% (Group B)

Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) supplementation has been used to improve cognitive outcomes in diseases associated with cognition. However, the influence of APOEε4 genotype on these relationships remains unclear. Therefore, this systematic review aims to discuss the evidence regarding the effects of DHA and EPA supplementation on cognitive decline variables and relate them to APOEε4 genotype in middle-aged and older adults. The Medline (via PubMed), Scopus, Web of Science, and Bireme/Lilacs databases were searched for studies, retrieving 1863 articles. After the step selection, two randomized clinical trials (RCTs) that evaluated the effects of EPA and DHA supplementation on cognitive variables were included. All the methodological steps were performed by two raters. The results of the RCTs were not congruent, as the non-carriers in the APOEε4 supplemented group performed worse in the quick-choice reaction time cognitive domain, whereas the carriers improved in the reasoning domain. The increase in DHA concentration in the supplemented group was lower in APOEε4 carriers than in individuals with other genotypes. Additionally, a smaller decline in right hippocampal brain volume correlated with higher EPA concentrations after supplementation in APOEε4 non-carriers. The dosage and supplementation time (18 months) were similar between studies. In conclusion, DHA and EPA supplementation showed no pragmatic effects on cognitive variables when considering the presence of the APOEε4 allele.

Background and Aim: Treatment of endometriosis involves pain relief which is achieved through the administration of analgesics and non-steroidal anti-inflammatory drugs, with or without the addition of hormone therapy. At present, studies investigating endometriosis pain management using experimental rat models and the use of medications are scarce. Therefore, this study aimed to systematically evaluate research trends and critical points in the field of endometriosis pain management using experimental models. Materials and Methods: A total of 30 publications related to this topic that were published from 2012 to 2022 were retrieved from various databases, including Web of Science, Scopus, PubMed, Embase, and CINAHL, using appropriate English keywords. The quality of the publications was evaluated using impact metrics, productivity, term density mapping, and author network. Results: The average publication rate was three articles per year, reaching its peak in 2021 at five articles per year. The United States and China were found to be the most productive countries, with 12 and 10 publications per year, respectively. The field of medicine (37.0%) was the most abundant, although the H-index was relatively low (13:13). Term density mapping involved the search of 542 keywords, of which 35 were selected, with only 8 exhibiting significant density. Conclusion: In the past decade, there has been a shortage of publications that have addressed pain in endometriosis in experimental models and, within this context the majority of the production and publication in this field has been performed by the United States and China. After performing this bibliometric review, it can be inferred that more research is required in this field, to develop new approaches and treatments for endometriotic pain.

The pequi (Caryocar brasiliense) fruit peel, despite being frequently discarded, has a high content of bioactive compounds, and therefore has a high nutritional value. The present study aimed to explore the bioactivities in the pequi peel, particularly their potential health benefits at the level of antioxidant activity. The exploitation of this fruit could also present significant economic benefits and applications of pequi by-products would represent a reduction in waste, having a positive impact on the environment. Phenolic compounds present in the pequi exocarp and external mesocarp were identified by paper spray mass spectrometry (PS-MS) and quantified by HPLC. The total phenolic content (TPC) along with the amount of 2,2-diphenyl-1-picrylhydrazyl (DPPH), Ferric Reducing Antioxidant Power (FRAP), and the amount of 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS) were also determined in peel extracts. Epicatechin was the most abundant phenolic compound found, followed by the caffeic, salicylic, and gallic acids. In addition, fingerprinting revealed compounds related to several beneficial health effects. In short, the results obtained were encouraging for potential applications of pequi peel in the field of functional foods.

Abstract Objective Evaluate the effect of combined training on body image (BI), body composition and functional capacity in patients with breast cancer. As also the relationship of BI with body composition and functional capacity. Methods This was a Controlled Clinical Trial study, this study including 26 patients with breast cancer (30 to 59 years). The training group (n = 13) underwent 12 weeks of training, including three 60-min sessions of aerobic exercise and resistance training, and two sessions of flexibility training per week; each flexibility exercise lasted 20s. The Control Group (n = 13) received only the standard hospital treatment. Participants were evaluated at baseline and after 12 weeks. BI (primary outcomes) was assessed using the Body Image After Breast Cancer Questionnaire; Body composition was estimated with the indicators: Body mass index; Weight, Waist hip Ratio; Waist height ratio; Conicity index; Reciprocal ponderal index; Percentage of fat; Circumference of the abdomen and waist; Functional capacity by cardiorespiratory fitness (cycle ergometer) and strength (manual dynamometer). The statistic was performed in the Biostatistics and Stata 14.0 (α = 5%). Results The patients in the training group showed a reduction in the limitation dimension (p = 0.036) on BI, However, an increase in waist circumference was observed in both groups. In addition an increase in VO2max (p < 0.001) and strength in the right (p = 0.005) and left arms (p = 0.033). Conclusion Combined training demonstrates to be an effective and non-pharmacological strategy to patients with breast cancer, with improvement on BI and functional capacity, changing related variables negatively when there is no physical training.

RESUMO Objetivo Identificar e correlacionar as queixas de alterações miofuncionais orofaciais e de risco para distúrbios respiratórios do sono com hábitos de sono na infância. Método Participaram 71 pais ou responsáveis de crianças de 6 a 11 anos, matriculadas em uma escola pública. Foi aplicado um formulário com questões semiestruturadas/anamnese e os protocolos Nordic Orofacial Test-Screening - entrevista, Pediatric Obstructive Sleep Apnea Screening Tool Questionnaire, e Children’s Sleep Habits Questionnaire - todos em suas versões em português/Brasil no formato online. Para a análise estatística, realizou-se o teste de correlação de Spearman, considerando o nível de significância de 5%. Resultados 29 crianças eram do sexo feminino (40,8%) e 42 do sexo masculino (59,2%), com média de idade de 8,52 anos. As queixas miofuncionais orofaciais encontradas foram relacionadas às funções de respiração (35,2%), mastigação e deglutição (32,4%) e hábitos deletérios (33,8%). Todas as crianças apresentaram um baixo risco para distúrbios respiratórios do sono e quanto aos hábitos de sono, 23 crianças (32,39%) apresentaram uma somatória menor, enquanto que 48 crianças (67,61%) ultrapassaram 41 pontos. Conclusão Houve correlação entre risco para distúrbios respiratórios do sono em crianças com as queixas de alterações miofuncionais orofaciais e com a baixa qualidade/maus hábitos de sono.

ABSTRACT: Leptospirosis, a disease of significant economic impact on livestock and public health concern, may exhibit unique epidemiological characteristics in indigenous villages, particularly those located within semiarid climates such as the Caatinga biome in Brazil. This environment often presents conditions unfavorable for leptospire survival. This study conducted serological diagnoses of livestock in indigenous villages within the Caatinga biome, Northeastern Brazil. The survey was carried out in the Mãe Maria and Santa Helena indigenous villages, home to the Xukuru de Cimbres tribe, in the county of Pesqueira, Pernambuco State, Brazil, within the Caatinga biome. Blood samples were collected from cattle (n = 42), goats (n = 41), and sheep (n = 19). Out of the 102 samples tested, 73 (71.6%; 95% CI = 62.8% - 80.3%) were seroreactive (cut-off ≥ 100). The seropositivity rates for cattle, goats, and sheep were 54.8%, 80.5%, and 89.5%, respectively. A statistically significant difference was observed in the proportion of seropositive animals between cattle and goats and cattle and sheep (P < 0.05). Icterohaemorrhagiae was identified as the most probable serogroup across all animal species. The study revealed that livestock in indigenous villages within the Caatinga biome are frequently exposed to leptospires. This finding underscores the importance of a One Health approach, emphasizing the need for comprehensive studies in areas where large human and animal populations coexist. Such studies are crucial for investigating zoonotic infections and for planning and implementing control measures against livestock-associated leptospirosis.

Abstract Background Prediabetes (PD) is defined as impaired fasting glucose and/or impaired glucose tolerance (IGT) and may be associated with high risk of cardiovascular injury. It is recommended that PD patients be screened for signs of arterial stiffness and cardiovascular injury to reinforce therapeutic strategies. Objectives To identify pulse wave velocity values discriminative for arterial stiffness and cardiovascular injury in PD patients. Methods A cross-sectional study was conducted with PD (N=43) and normoglycemic (N=37) patients who underwent clinical evaluation, arterial stiffness assessment by carotid-femoral pulse wave velocity (cfPWV) using SphygmoCor, laboratory blood analysis, investigation of morphological and functional cardiac variables by transthoracic echocardiogram, and assessment of carotid intima-media-thickness (CIMT) by carotid ultrasonography. A statistical analysis was performed using SPSS software and values of p

Buscou-se caracterizar as práticas pedagógicas utilizadas nos cursos de Licenciatura em Educação Física durante a pandemia de covid-19. Trata-se de um estudo descritivo com abordagem quantitativa realizado entre os meses de outubro de 2020 e julho de 2021. Os dados foram coletados via Google Formulários. A amostra foi composta por 27 professores de IES públicas e privadas. Os dados foram analisados por meio da estatística descritiva. Encontrou-se que o método de ensino mais utilizado foi o remoto. Encontrou-se as seguintes prevalências: métodos avaliativos - avaliações objetivas e os seminários; plataforma - Google Meet; dificuldades de docentes e estudantes - fácil dispersão dos alunos e a baixa qualidade da conexão da internet. Conclui-se que, apesar da imposição emergencial da utilização do meio virtual para o ensino e da falta de suporte financeiro, os professores se adaptaram às demandas de ensino remoto e apontam que o aprendizado gerado se faz significativo.

Background Animal models are commonly used to assess the efficacy of new materials to be employed in the surgical repair of a nerve injury. However, there is no published surgical repair protocol for sciatic nerve neurotmesis in rats.

Aims: To investigate the associations of 25-hydroxyvitamin D (25(OH)D) concentrations, vitamin D intake, magnesium, and calcium with glycemic control in individuals with type 2 diabetes mellitus (T2DM). Methods: A total of 107 adult with T2DM, residing in the state of Sergipe/Brazil (latitude: 10°), were evaluated for serum concentrations of 25(OH)D, parathyroid hormone, fasting glucose, %HbA1c, insulin, C-peptide, total cholesterol and fractions, homeostasis of beta-cell function (HOMA-B), insulin sensitivity (HOMA-S) and resistance (HOMA-IR), anthropometry, body composition, and usual food intake. The results were analyzed according to 25(OH)D status (insufficient/deficient

Leptospirosis is an infectious disease that affects domestic animals, wild animals, and humans. It represents a public health problem and has an important economic impact on livestock. This study aims to investigate the importance of genital and transplacental infection in the epidemiology of leptospirosis in cows maintained in Caatinga biome conditions, Northeastern Brazil, as well as reporting organs colonized by Leptospira spp. in embryos and fetuses. Blood, urinary tract (urine, bladder, and kidney), and reproductive tract (vaginal fluid, uterus, uterine tube, ovary, and placenta) samples were collected from 15 slaughtered pregnant cows. Two embryos and 13 fetuses were sampled. Central nervous system and choroid ovoid samples were collected from embryos. Blood, central nervous system, lung, peritoneal liquid, abomasal content, liver, spleen, urine, bladder, kidney, and reproductive system samples were collected from fetuses. Diagnostic methods included the microscopic agglutination test (MAT) using a collection of 24 serovars belonging to 17 different pathogenic serogroups of five species as antigens, as well as polymerase chain reaction (PCR). Anti-Leptospira spp. antibodies were found in 9 cows (60%), while 13 cows (86.67%) had at least one organ or urine with leptospiral DNA. No fetus was seroreactive. Among the embryos and fetuses, 13 (86.67%) presented leptospiral DNA, proving a high frequency of transplacental infection (100%). For cows, the most frequent biological materials regarding Leptospira spp. DNA detection were placenta (13 out of 15 samples; 86.7%), uterus (10 out of 15 samples; 66.7%), and vaginal fluid (5 out of 15 samples; 33.3%), while, for fetuses/embryos, the most frequent PCR-positive samples were choroid ovoid (1/2; 50%), spleen (6/13; 46.2%), kidney (5/13; 38.5%), and central nervous system (5/15; 33.3%). Sequenced samples based on the LipL32 gene presented 99% similarity with L. borgpetersenii. The results indicate that transplacental infection is an efficient way of spreading Leptospira spp. in cows maintained in Caatinga biome conditions. Therefore, prevention and control strategies must include actions that interrupt transmission through this alternative route.

Osteoarthritis (OA) remains a chronic incurable condition, presenting substantial challenges in treatment. This study explores a novel strategy by investigating the concurrent use of cuminaldehyde, a natural compound, with indomethacin in animal models of MIA-induced OA. Our results demonstrate that the co-administration of cuminaldehyde and indomethacin does indeed produce a superior effect when compared to these compounds individually, significantly enhancing therapeutic outcomes. This effect is evidenced by a marked reduction in pro-inflammatory cytokines IL-6 and IFN-γ, alongside a significant increase in the anti-inflammatory cytokine IL-10, compared to treatments with each compound alone. Radiographic analyses further confirm the preservation of joint integrity and a reduction in osteoarthritic damage, highlighting the association’s efficacy in cartilage-reducing damage. These findings suggests that the association of cuminaldehyde and indomethacin not only slows OA progression but also offers enhanced cartilage-reducing damage and fosters the production of protective cytokines. This study underscores the potential benefits of integrating natural products with pharmaceuticals in OA management and stresses the importance of further research to fully understand the mechanisms underlying the observed potentiated effects.

ABSTRACT Objective: To identify the predictors of self-care behaviors in individuals with heart failure. Method: A cross-sectional study including 405 patients with heart failure. Self-care behaviors were assessed by the Self-Care of Heart Failure Index. Sociodemographic and clinical characteristics were investigated as predictors of self-care maintenance, management and confidence through logistic regressions. Results: The predictors of self-care maintenance were number of children (p

Resumo Objetivo Avaliar a qualidade do sono de profissionais dos serviços de emergência e sua associação com o nível de fadiga e qualidade de vida. Métodos Estudo descritivo, transversal e correlacional, realizado nas unidades do Serviço de Atendimento Móvel de Urgência (SAMU) e na Unidade de Pronto Atendimento (UPA), no ano de 2021, com 108 participantes. Para avaliação da qualidade do sono, foi utilizado o Índice de Qualidade do Sono de Pittsburgh versão Brasileira (PSQI-BR); para avaliação da Fadiga, foi utilizada a Escala de Fadiga de Chalder, em conjunto com a Escala de Necessidade de Descanso (ENEDE); e para avaliação da qualidade de vida, foi utilizado o World Health Organization Quality of Life Brief Version (WHOQOL-bref), sendo que os instrumentos utilizados foram adaptados para a língua portuguesa em estudos anteriores. Foram aplicados testes de associação para a análise estatística, tendo sido utilizados o Teste Qui-Quadrado de Pearson, o Teste U Mann-Whitney ou Kruskal Wallis e a correlação de Spearman. Valores de p

ABSTRACT Objective: To analyze the evidence of content validity of telephone messages regarding preventive measures against COVID-19. Method: Methodological study, in which messages containing text and image were developed through a narrative literature review and whose content was evaluated by eight judges in terms of clarity, practical relevance, theoretical relevance and vocabulary. The content validity index (CVI) was calculated, and messages that reached levels above 90% were considered to have adequate evidence of validity. Results: Eighteen text messages/images were developed containing information about COVID-19, hand hygiene, use and handling of masks and the importance of social distancing. After second round of evaluation, a content validity index above 90% was obtained in all evaluated indicators. Conclusion: The telephone messages were developed and showedadequate evidence of content validity.

O objetivo principal deste artigo foi investigar a relevância dos laços afetivos na educação musical de crianças autistas. Em vista disso, serão apresentadas três atividades musicais no decorrer deste trabalho denominadas “Jogo de imitações”, “Jogo da memória” e “Paisagem sonora”. Essas atividades foram elaboradas para enfatizar claramente os laços afetivos desenvolvidos entre a professora e as crianças com Transtorno do Espectro Autista (TEA). A partir do esboço e da discussão em torno dessas três atividades musicais, foi possível perceber que os laços afetivos entre a professora e as crianças foram importantes durante a mediação das atividades, e que a relação afetiva auxiliou na aprendizagem musical das crianças autistas. Enfatizamos a importância da elaboração e realização de atividades musicais baseadas no afeto, assim como a atenção às particularidades das crianças dentro do espectro autista, podendo assim colaborar para uma aprendizagem adaptada incentivando o desenvolvimento musical e uma educação musical mais inclusiva. Além disso, esperamos incentivar os professores de música e de outras áreas a desenvolver práticas inclusivas com crianças que apresentam necessidades específicas por meio de atividades baseadas no afeto.

This clinical guideline supported by the Brazilian Sleep Association comprises a brief history of the development of Brazilian sleep physiotherapy, outlines the role of the physiotherapist as part of a sleep health team, and describes the clinical guidelines in respect of the management of some sleep disorders by the physiotherapist (including sleep breathing disorders, i.e., obstructive sleep apnea, central sleep apnea, upper airway resistance syndrome, hypoventilation syndromes and overlap syndrome, and pediatric sleep breathing disorders; sleep bruxism; circadian rhythms disturbances; insomnia; and Willis-Ekbom disease/periodic limb movement disorder. This clinical practice guideline reflects the state of the art at the time of publication and will be reviewed and updated as new information becomes available.

ABSTRACT Objectives: to assess the evidence of reliability and convergent construct validity of the King’s Parkinson’s Disease Pain Questionnaire. Methods: psychometric study of 75 older adults with Parkinson’s disease. The instrument was applied by two researchers separately and reapplied by one researcher 15 days later. In terms of reliability, internal consistency was assessed using the Cronbach’s alpha test and stability using the intraclass correlation coefficient. Scores of the King’s Parkinson’s Disease Pain Questionnaire were compared to those of the Geriatric Pain Measure in the assessment of construct validity. Results: the mean Cronbach’s alpha obtained between the three assessments was above 0.60, the intraclass correlation between the three assessments was above 0.90, and there was a weak but significant correlation between the two applied scales. Conclusions: the instrument showed adequate evidence of convergent construct validity and reliability, and can be used in clinical practice.

Os rituais sagrados no Semiárido Brasileiro configuram-se como uma das multiplicidades de saberes sociais e humanos, que constituem esse ambiente. Buscou-se analisar as dimensões espirituais vivenciadas no Semiárido Brasileiro, tendo como referência dois territórios: um situado no Submédio São Francisco, a ilha do Massangano, comunidade rural negra pertencente ao município da cidade de Petrolina/PE e o quilombo de Laje dos Negros, no município de Campo Formoso, no estado da Bahia. A metodologia utilizada para seleção dos participantes da pesquisa foi a técnica Snowbal. Os resultados mostram que as expressões religiosas dos locais estudados abarcam valores profanos como religiosos e geraram, com o passar do tempo, formas próprias de resistência às influências externas e, consequentemente, proteção dos saberes tradicionais nessas comunidades. As manifestações religiosas possuem uma simbologia cultural replicada a partir das tradições e da memória, constituindo, assim, a identidade dos membros, que compõem as duas comunidades estudadas.

The jump is one of the main body elements in Rhythmic Gymnastics (RG). To perform it correctly, gymnasts must develop appropriate force and velocity levels to reach enough jump height to show the body shape during flight, as defined by the RG Code of Points. Jumping performance is influenced by the mechanical force-velocity (F-V) profile and the maximum power generated by the lower limbs. The F-V profile identification can provide a more accurate and complete mechanical representation of its capabilities and needs. This study aimed to analyse the F-V profile during the counter movement jump of RG athletes, identify the magnitude and direction of the imbalance between the two variables (force and velocity), and compare the jumping ability and mechanical variables of different age groups. Eighteen Portuguese gymnasts (average age 12.2±1.8 years) were evaluated, according to age group: beginner and youth gymnasts (G1- ages 10 to 12) and junior and senior gymnasts (G2 - ages 13 to 16), and according to the F-V profile imbalance detected. The data collection was performed after a covid-19 lockdown period. Results showed anthropometric differences between age groups but no differences in the F-V profile related variables. When gymnasts were compared according to the deficit, differences were found in variables force and velocity. Furthermore, 72.3% of the gymnasts presented force deficit, 11% presented velocity deficit and 16.6% were balanced. Considering the deficits found, the demands of the sport and of each athlete, it is essential to include strength training in the regular training routines of rhythmic gymnasts.

Este artigo tem como objetivo avaliar alguns impactos econômicos da implementação da rede 5G no setor de Tecnologia da Informação e Comunicação (TIC) brasileiro, em decorrência das novas demandas por soluções digitais inovadoras. O artigo baseia-se nas perspectivas teóricas da economia da inovação desenvolvidas por Schumpeter e nos conceitos de paradigmas e trajetórias tecnológicas desenvolvidos pela escola Neoschumpeteriana. A metodologia adotada inclui uma revisão da literatura sobre teorias da inovação e autores que aplicam esses conceitos ao desenvolvimento do setor de TIC. Além disso, foram realizadas entrevistas com profissionais da área de TIC para avaliar suas percepções sobre os alguns dos possíveis impactos econômicos da implantação do 5G no Brasil. Os resultados obtidos por meio da literatura permitem situar os efeitos da evolução da tecnologia 5G como uma trajetória tecnológica presente nos paradigmas tecnológicos das áreas de comunicação e informação, e as a análise das entrevistas mostra que mais de 80% dos participantes acreditam que haverá um aumento na demanda por soluções digitais TIC, sendo que o setor do agronegócio será o maior impulsionador dessas demandas, com investimentos em infraestrutura de TI e adaptações de soluções já existentes em IoT, Big Data, Inteligência Artificial e softwares sob demanda.

This paper presents the comprehensive state-of-the-art on the challenges that short sea shipping currently faces across the world. The concept and its relationship with coastal shipping are introduced, followed by a review of the EU policies for short sea shipping and its practical impacts in modal split. A survey of the literature on the strong and weak points of this form of transportation is carried out, aimed at explaining the difficulties in achieving relevant modal shifts from road to sea. The experience with short sea shipping across the world is described and discussed, providing a global perspective. The paper then discusses the main challenges and opportunities in this field, namely decarbonisation, autonomous navigation, and digitalization. Conclusions are drawn on the possible impact of these game changing developments in this segment of the shipping industry.

Com o objetivo de conhecer inovações promovidas em modelos de negócios para diferenciar a proposta de valor em busca de vantagem competitiva, a elaboração deste estudo principiou por uma pesquisa bibliográfica em que se buscou conhecer os principais conceitos e exemplos relativos à inovação para a competitividade, inovação em modelos de negócios e proposta de valor para a vantagem competitiva. Em seguida, procurou-se identificar modelos atuais de negócio que se encaixassem na proposta da pesquisa, ou seja, empresas que oferecem e agregam valor aos seus clientes mediante processos e oferta de soluções que evidenciam práticas inovadoras. Com esse propósito, recorreu-se a entrevistas para conhecer opiniões e percepções de gestores em organizações de variados setores. Os dados obtidos foram interpretados por meio de análise de conteúdo, que originou a identificação de categorias temáticas, possibilitando estruturar os aspectos revelados na visão declarada dos participantes, e seus respectivos impactos nas estratégias de atuação de suas empresas no mercado. Os resultados possibilitaram o alcance do objetivo geral da pesquisa, uma vez que os achados possibilitam agregar conhecimento sobre modelos inovadores de negócio e propostas de valor idealizadas com base na busca pela competitividade, além de conhecer exemplos de inovação na oferta de serviços e produtos.

Thiago Alves Rodrigues, Eduardo José Silva Gomes de Oliveira, Beatriz Morais Costa, Rayanne Luiza Tajra Mualem Araújo, João Batista Santos Garcia Chronic Pain Clinic, University Hospital of the Federal University of Maranhão (HU-UFMA), São Luís, Maranhão, BrazilCorrespondence: Thiago Alves Rodrigues, Chronic Pain Clinic, University Hospital of the Federal University of Maranhão (HU-UFMA), Rua do Farol, n. 05. Ed Porto Real, Ap 1101, Ponta do Farol, São Luis, Maranhão, Brazil, CEP 65077-450, Email thiagoalves2005@gmail.comIntroduction: Patients with post-surgery persistent spinal pain syndrome (PSPS) or non-surgical PSPS might be affected by sustained fear-avoidance beliefs (FAB), anxiety and depression. In this scenario, this study aimed to describe those aspects in patients with post-surgery PSPS and non-surgical PSPS.Methods: This study included patients with PSPS, and non-surgical PSPS, over 18 years, with quarterly evaluations at the Chronic Pain Clinic. After evaluation, demographic and clinical characteristics were obtained. The Beck Depression Inventory-II, Beck Anxiety Inventory, Douleur neuropathique 4 questions, Visual Analog Pain Scale, and Fear-Avoidance Beliefs Questionnaire–Brazilian Version (FABQ-Brazil) were used to evaluate psychological aspects.Results: Forty-six patients were included, 23 patients with post-surgery PSPS and 23 with non-surgical PSPS. Both groups had high scores in the physical and work domains of the FABQ, high rates of absenteeism and most patients in these groups had moderate-to-severe neuropathic pain and some degree of anxiety and/or depression. The groups showed no statistically significant difference (p > 0.05) when comparing all questionnaires.Discussion: This is one of the first studies to evaluate FAB and other associated psychological factors, such as anxiety and depression, in patients with post-surgery PSPS in a follow-up several years after surgery and compare with patients diagnosed with non-surgical PSPS. In this study, most patients in both groups had high scores in the FABQ domains, not having statistically relevant difference between groups.Conclusion: Even though there was no statistically relevant difference between the PSPS patient with or without surgical history in terms of the assessed outcome measures, the described scores for fear-avoidance beliefs, pain, anxiety and depression were high, showing an interference in the daily life activities of those patients.Keywords: fear, depression, anxiety, spine surgery, back pain

Abstract We aimed to determine the herd and animal levels seroprevalence and associated factors for Toxoplasma gondii infections in cattle from the state of Paraíba, Northeastern Brazil. Herds (n = 434) and cows aged ≥ 24 months (n = 1,895) were randomly selected, and serum samples were tested with the immunofluorescence antibody test (IFAT) using as cutoff of 64. Of the 434 farms investigated, 197 had at least one seropositive cow (prevalence of 49.0%; 95% CI = 44.3%-53.8%), and the prevalence at animal level was 18.0% (95% CI = 5.3%-21.1%). The antibody titers ranged from 64 to 1024, with the most frequent titers being 64 (10.8%) and 128 (3.7%). The risk factors identified were property located in Sertão region (odds ratio [OR] = 3.07), property located in Agreste/Zona da Mata regions (OR = 2.00), animal purchasing (OR = 2.68), herd size of 34-111 animals (OR = 2.91) and herd size > 111 animals (OR = 6.97). The results suggest the wide distribution of T. gondii infections in cattle throughout the state of Paraíba, and the risk factors identified are not possible to correct.

Leukemia is among the most common types of hematological cancers and the use of herbal medicines to prevent and treat leukemia are under quick development. Among several molecular pathways involved in leukemia pathogenesis and exacerbations, purinergic signaling is revealed as a key component. In the present study, the effects of two doses (5 ug/mL and 10 ug/mL) of Immunity-6™, a phytocomplex composed by beta-glucan, green tea (Camelia sinensis), chamomile (Matricaria chamomilla), and ascorbic acid (vitamin C) was tested in vitro, using chronic myelogenous leukemia cell line (K-562; 5 ×104/mL/well), which were challenged with lipopolysaccharide (LPS; 1 ug/mL) for 24 h. The results demonstrated that both doses of Immunity-6™ inhibited ATP release (p

Background: Heart failure demands self-care skills and behaviors that can be negatively impacted by a low level of perceived control (PC), a belief about having the necessary resources to deal with negative events. Having valid and reliable instruments to measure PC is important to support interventions that improve self-care and related outcomes. The Control Attitudes Scale-Revised (CAS-R)was developed in the United States to measure PC in cardiac conditions. In Brazil, there are no instruments available to measure this construct. Objective: The aims of this study were to translate and adapt the CAS-R to the Brazilian population and to assess the content validity of the adapted version. Methods: The CAS-R was translated, back-translated, and assessed by an expert committee for linguistic equivalences. An agreement > 80%was considered adequate. Content validity (clarity, theoretical relevance, and practical pertinence) wasassessedbyboth an expertprofessionalpanel (n=6-8) and a panel of patientswith heart failure (n = 40). A content validity coefficient > 0.70was considered acceptable. Results: The translations to Brazilian Portuguesewere considered consistentwith the original CAS-R. In the third round of linguistic equivalence assessment, all items achieved acceptable agreement, except for 2 items. After modifications to the instrument to achieve adequate equivalences, the adapted version had a final content validity coefficient of 0.93. Most patients were able to understand the instrument. Conclusions: The CAS-R-Brazilian version is equivalent to the original CAS-R and has satisfactory evidence of content validity. Additional psychometric testing will be performed to allow for the assessment of PC in individuals with heart failure in Brazil. [ABSTRACT FROM AUTHOR]

ABSTRACT Objectives: to develop and analyze content validity evidence of a website for patients with coronary artery disease. Methods: a methodological study, carried out in the phases: Definition - determined contents for inclusion in the website, architecture and design; Implementation - subjects included in the website; Assessment - website submitted to analysis by 13 experts and eight laypersons regarding organization, content and design, on a scale of 1 (no agreement) to 4 (complete agreement). Items that reached Content Validity Ratio (CVR) higher than the established critical values and Content Validity Index greater than 0.80 were considered valid. Results: eight domains related to secondary prevention in coronary heart disease were included on the website. Critical CVR and adequate CVI were obtained according to professional and lay experts. Conclusions: the website was developed, achieving adequate content validity evidence, and can be used as an educational tool for this population.

Buscou-se relatar a experiência de um profissional de educação física no desenvolvimento de Projetos Terapêuticos Singulares (PTS) utilizados no acompanhamento de usuários em sofrimento mental de um CAPSad da região metropolitana Fortaleza-CE. Trata-se de uma pesquisa do tipo relato de experiência com abordagem qualitativa realizada de janeiro de 2021 a fevereiro de 2022. Os resultados indicam que a participação do profissional de educação física residente foi de grande importância desde o planejamento do PTS junto às equipes multidisciplinares aos acompanhamentos individuais e/ou coletivos dos usuários e seus familiares no contexto de recuperação. O cuidado integral e participativo contribuiu no desenvolvimento da autonomia dos sujeitos rumo à responsabilização do próprio cuidado.

ABSTRACT: Animal hoarding disorder, especially dogs and cats, is a complex issue that occurs in almost all communities, and it is necessary to collect data that contribute to the understanding of leptospirosis within the One Health initiative. In order to determine the seroprevalence of Leptospirasp., 71 dogs and 39 cats from 33 people with animal hoarding profile in the municipality of Patos, state of Paraíba, semi-arid region of Northeastern Brazil were evaluated by using the microscopic serum agglutination test (MAT) as diagnostic test. Thirty-eight animals (34.5%; 95% CI = 25.7 - 43.4%) were seroreactive, with 46.5% in dogs and 12.8% in cats (P < 0.01), with the highest frequency of the Icterohaemorrhagiae serogroup in both species. The high seroprevalence reported suggests the need for public policies for this vulnerable population in order to prevent the transmission of zoonoses.