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12 results on '"Batista, Ana Beatriz"'

4. Unravelling the Gut Microbiome Role in Cardiovascular Disease: A Systematic Review and a Meta-Analysis.

Author

Martins, Diana, Silva, Cláudia, Ferreira, António Carlos, Dourado, Sara, Albuquerque, Ana, Saraiva, Francisca, Batista, Ana Beatriz, Castro, Pedro, Leite-Moreira, Adelino, Barros, António S., and Miranda, Isabel M.

Subjects
GUT microbiome, TRIMETHYLAMINE oxide, HDL cholesterol, CARDIOVASCULAR diseases, HUMAN microbiota, BACTERIAL population
Abstract

A notable shift in understanding the human microbiome's influence on cardiovascular disease (CVD) is underway, although the causal association remains elusive. A systematic review and meta-analysis were conducted to synthesise current knowledge on microbial taxonomy and metabolite variations between healthy controls (HCs) and those with CVD. An extensive search encompassing three databases identified 67 relevant studies (2012–2023) covering CVD pathologies from 4707 reports. Metagenomic and metabolomic data, both qualitative and quantitative, were obtained. Analysis revealed substantial variability in microbial alpha and beta diversities. Moreover, specific changes in bacterial populations were shown, including increased Streptococcus and Proteobacteria and decreased Faecalibacterium in patients with CVD compared with HC. Additionally, elevated trimethylamine N-oxide levels were reported in CVD cases. Biochemical parameter analysis indicated increased fasting glucose and triglycerides and decreased total cholesterol and low- and high-density lipoprotein cholesterol levels in diseased individuals. This study revealed a significant relationship between certain bacterial species and CVD. Additionally, it has become clear that there are substantial inconsistencies in the methodologies employed and the reporting standards adhered to in various studies. Undoubtedly, standardising research methodologies and developing extensive guidelines for microbiome studies are crucial for advancing the field. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Critically ill COVID-19 patients in northeast Brazil: mortality predictors during the first and second waves including SAPS 3

Author

Lázaro, Ana Paula Pires, primary, Albuquerque, Polianna Lemos Moura Moreira, additional, Meneses, Gdayllon Cavalcante, additional, Zaranza, Marza de Sousa, additional, Batista, Ana Beatriz, additional, Aragão, Natalia Linhares Ponte, additional, Beliero, Andrea Mazza, additional, Guimarães, Álvaro Rolim, additional, Aragão, Nilcyeli Linhares, additional, Leitão, Alessandra Marjorye Maia, additional, de Carvalho, Marcelo Costa Freire, additional, Cavalcante, Maria Isabel de Alencar, additional, Mota, Fabio Augusto Xerez, additional, Daher, Elizabeth De Francesco, additional, Martins, Alice Maria Costa, additional, and da Silva Junior, Geraldo Bezerra, additional

Published
2022
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9. Hérnia de Richter

Author

Batista, Ana Beatriz Esteves, primary, Borges Tavares Vieira, Richard Raphael, additional, Araújo, Ana Claudia Aguiar Alves, additional, Pentagna, Bernardo Teixeira, additional, De Paula, Joaquim Ferreira, additional, and Batista, Carlos Augusto Marques, additional

Published
2019
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