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7. A novel approach to accurately measuring the burden of hospitalisations for cardiovascular disease in people with diabetes: A pilot study.

Author

Huynh, Quan, Burgess, John, Flentje, Kate, Tan, Neville, Batchelor, Riley, Marwick, Thomas H., and Shaw, Jonathan E.

Subjects
MYOCARDIAL infarction diagnosis, DIABETES complications, STROKE diagnosis, CARDIOVASCULAR diseases, RESEARCH funding, HOSPITAL care, STATISTICAL sampling, PILOT projects, CARDIOVASCULAR diseases risk factors, HEART failure, RETROSPECTIVE studies, DESCRIPTIVE statistics, LONGITUDINAL method, MEDICAL coding, MEDICAL records, ACQUISITION of data, STATISTICS, CONFIDENCE intervals, DATA analysis software, ECONOMIC aspects of diseases, NOSOLOGY, SENSITIVITY & specificity (Statistics)
Abstract

Aim: To determine the reliability of hospital discharge codes for heart failure (HF), acute myocardial infarction (AMI) and stroke compared with adjudicated diagnosis, and to pilot a scalable approach to adjudicate records on a population‐based sample. Methods: A population‐based sample of 685 people with diabetes admitted (1274 admissions) to one of three Australian hospitals during 2018–2020 were randomly selected for this study. All medical records were reviewed and adjudicated. Results: Cardiovascular diseases were the most common primary reason for hospitalisation in people with diabetes, accounting for ~17% (215/1274) of all hospitalisations, with HF as the leading cause. ICD‐10 codes substantially underestimated HF prevalence and had the lowest agreement with the adjudicated diagnosis of HF (Kappa = 0.81), compared with AMI and stroke (Kappa ≥ 0.91). While ICD‐10 codes provided suboptimal sensitivity (72%) for HF, the performance was better for AMI (sensitivity 84%; specificity 100%) and stroke (sensitivity 85%; specificity 100%). A novel approach to screen possible HF cases only required adjudicating 8% (105/1274) of records, correctly identified 78/81 of HF admissions and yielded 96% sensitivity and 98% specificity. Conclusions: While ICD‐10 codes appear reliable for AMI or stroke, a more complex diagnosis such as HF benefits from a two‐stage process to screen for suspected HF cases that need adjudicating. The next step is to validate this novel approach on large multi‐centre studies in diabetes. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Sex differences among patients presenting to hospital with out‐of‐hospital cardiac arrest and shockable rhythm

Author

Ho, Felicia CS, primary, Zheng, Wayne C, additional, Noaman, Samer, additional, Batchelor, Riley J, additional, Wexler, Noah, additional, Hanson, Laura, additional, Bloom, Jason E, additional, Al‐Mukhtar, Omar, additional, Haji, Kawa, additional, D'Elia, Nicholas, additional, Kaye, David, additional, Shaw, James, additional, Yang, Yang, additional, French, Craig, additional, Stub, Dion, additional, Cox, Nicholas, additional, and Chan, William, additional

Published
2022
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12. Evaluation of factors associated with selection for coronary angiography and in‐hospital mortality among patients presenting with out‐of‐hospital cardiac arrest without ST‐segment elevation

Author

Zheng, Wayne C., primary, Noaman, Samer, additional, Batchelor, Riley J., additional, Hanson, Laura, additional, Bloom, Jason E., additional, Al‐Mukhtar, Omar, additional, Haji, Kawa, additional, D'Elia, Nicholas, additional, Ho, Felicia C. S., additional, Kaye, David, additional, Shaw, James, additional, Yang, Yang, additional, French, Craig, additional, Stub, Dion, additional, Cox, Nicholas, additional, and Chan, William, additional

Published
2022
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13. Incidence, predictors and clinical implications of new renal impairment following percutaneous coronary intervention

Author

Wong, Nathan, primary, Dinh, Diem T, additional, Brennan, Angela, additional, Batchelor, Riley, additional, Duffy, Stephen J, additional, Shaw, James A, additional, Chan, William, additional, Layland, Jamie, additional, van Gaal, William J, additional, Reid, Christopher M, additional, Liew, Danny, additional, and Stub, Dion, additional

Published
2022
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15. Sex differences among patients presenting to hospital with out‐of‐hospital cardiac arrest and shockable rhythm.

Author

Ho, Felicia CS, Zheng, Wayne C, Noaman, Samer, Batchelor, Riley J, Wexler, Noah, Hanson, Laura, Bloom, Jason E, Al‐Mukhtar, Omar, Haji, Kawa, D'Elia, Nicholas, Kaye, David, Shaw, James, Yang, Yang, French, Craig, Stub, Dion, Cox, Nicholas, and Chan, William

Subjects
CARDIOPULMONARY resuscitation, CONFIDENCE intervals, PSYCHOLOGY of cardiac patients, RETROSPECTIVE studies, SEX distribution, HEART sounds, TREATMENT effectiveness, COMPARATIVE studies, CORONARY angiography, CARDIAC arrest, HEALTH equity, LOGISTIC regression analysis, HEART diseases, LONGITUDINAL method
Abstract

Objective: Sex differences in patients presenting with out‐of‐hospital cardiac arrest (OHCA) and shockable rhythm might be associated with disparities in clinical outcomes. Methods: We conducted a retrospective cohort study and compared characteristics and short‐term outcomes between male and female adult patients who presented with OHCA and shockable rhythm at two large metropolitan health services in Melbourne, Australia between the period of 2014–2018. Logistic regression was used to assess the effect of sex on clinical outcomes. Results: Of 212 patients, 166 (78%) were males and 46 (22%) were females. Both males and females presented with similar rates of ST‐elevation myocardial infarction (44% vs 36%, P = 0.29), although males were more likely to have a history of coronary artery disease (32% vs 13%) and a final diagnosis of a cardiac cause for their OHCA (89% vs 72%), both P = 0.01. Rates of coronary angiography (81% vs 71%, P = 0.23) and percutaneous coronary intervention (51% vs 42%, P = 0.37) were comparable among males and females. No differences in rates of in‐hospital mortality (38% vs 37%, P = 0.90) and 30‐day major adverse cardiac and cerebrovascular events (composite of all‐cause mortality, myocardial infarction, coronary revascularization and nonfatal stroke) (39% vs 41%, P = 0.79) were observed between males and females, respectively. Female sex was not associated with worse in‐hospital mortality when adjusted for other variables (odds ratio 0.66, 95% confidence interval 0.28–1.60, P = 0.36). Conclusion: Among patients presenting with OHCA and a shockable rhythm, baseline sex and sex differences were not associated with disparities in short‐term outcomes in contemporary systems of care. [ABSTRACT FROM AUTHOR]

Published
2023
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16. Determinants of Undertaking Coronary Angiography and Adverse Prognostic Predictors Among Patients Presenting With Out-of-Hospital Cardiac Arrest and a Shockable Rhythm

Author

Zheng, Wayne C., primary, Noaman, Samer, additional, Batchelor, Riley J., additional, Hanson, Laura, additional, Bloom, Jason, additional, Kaye, David, additional, Duffy, Stephen J., additional, Walton, Antony, additional, Pellegrino, Vincent, additional, Shaw, James, additional, Yang, Yang, additional, French, Craig, additional, Stub, Dion, additional, Cox, Nicholas, additional, and Chan, William, additional

Published
2022
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17. ADVERSE PROGNOSTIC PREDICTORS AMONG PATIENTS PRESENTING WITH OUT-OF-HOSPITAL CARDIAC ARREST AND A SHOCKABLE RHYTHM

Author

Zheng, Wayne, primary, Noaman, Samer, additional, Batchelor, Riley, additional, Hanson, Laura, additional, Bloom, Jason, additional, Kaye, David, additional, Duffy, Stephen, additional, Walton, Tony, additional, Pellegrino, Vincent, additional, Yang, Yang, additional, French, Craig, additional, Cox, Nicholas, additional, Stub, Dion, additional, and Chan, William, additional

Published
2021
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18. CLINICAL OUTCOMES OF UNPROTECTED LEFT MAIN CORONARY ARTERY PERCUTANEOUS CORONARY INTERVENTION IN AUSTRALIAN NON-SURGICAL CENTRES

Author

Hanson, Laura, primary, Vogrin, Sara, additional, Noaman, Samer, additional, Goh, Cheng Yee, additional, Dinh, Diem, additional, Lefkovits, Jeffrey, additional, Reid, Christopher, additional, Brennan, Angela, additional, Zheng, Wayne, additional, Bloom, Jason, additional, Batchelor, Riley, additional, Haji, Kawa, additional, Koh, Youlin, additional, Stub, Dion, additional, Cox, Nicholas, additional, and Chan, William, additional

Published
2021
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19. Adverse impact of chronic kidney disease on clinical outcomes following percutaneous coronary intervention

Author

Bloom, Jason E, primary, Dinh, Diem T, additional, Noaman, Samer, additional, Martin, Catherine, additional, Lim, Michael, additional, Batchelor, Riley, additional, Zheng, Wayne, additional, Reid, Christopher, additional, Brennan, Angela, additional, Lefkovits, Jeffrey, additional, Cox, Nicholas, additional, Duffy, Stephen J, additional, and Chan, William, additional

Published
2020
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