1. Maxillary mucormycosis and aspergillosis in post-COVID-19 patients in Mexico: A case series.
- Author
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Urias-Barreras CM, Rodríguez-Archilla A, Canizalez-Roman A, Bastidas DA, and León-Sicairos NM
- Subjects
- Humans, Mexico epidemiology, Cross-Sectional Studies, Retrospective Studies, SARS-CoV-2, Mucormycosis complications, Mucormycosis diagnosis, Mucormycosis epidemiology, COVID-19 complications, COVID-19 epidemiology, Aspergillosis diagnosis, Aspergillosis epidemiology, Aspergillosis etiology, Osteonecrosis
- Abstract
Background: Fungal infections, during or as a consequence of SARS-CoV-2 infection, associated with uncontrolled diabetes mellitus and indiscriminate use of corticosteroids have been reported. In the jaw, mostly mucormycosis has been diagnosed in hospitals., Methods: A retrospective, cross-sectional, descriptive study of the clinical, imaging, and histopathologic characteristics of maxillary invasive fungal infection in post-COVID-19 patients diagnosed in a private non-hospital oral pathology service in Mexico during 2020-2022 was conducted., Results: We found 20 cases of maxillary invasive fungal infections in post-COVID-19 patients, 75% including a diagnosis of mucormycosis and 25% diagnosed as probable aspergillosis. The most common signs and symptoms were exposed necrotic bone followed by tooth mobility, discharge, and pain. On imaging, unilateral maxillary sinus involvement was observed in 6 cases (30%), and bilateral maxillary sinus involvement was observed in 3 cases (15%)., Conclusions: It is essential to consider the association of osteonecrosis of the jaw in post-COVID-19 patients, with aspergillosis, not only mucormycosis, for early diagnosis and appropriate treatment., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Masson SAS. All rights reserved.)
- Published
- 2024
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