1. Phage small proteins play large roles in phage-bacterial interactions.
- Author
-
Beggs GA and Bassler BL
- Subjects
- Bacterial Physiological Phenomena, Bacteriophages physiology, Bacteriophages genetics, Bacteriophages metabolism, Bacteria virology, Bacteria metabolism, Bacteria genetics, Viral Proteins metabolism, Viral Proteins genetics
- Abstract
Phages have wide influence on bacterial physiology, and likewise, bacterial processes impinge on phage biology. Key to these interactions are phage small proteins (<100 aa). Long underappreciated, recent work has revealed millions of phage small proteins, and increasingly, mechanisms by which they function to dictate phage and/or bacterial behavior and evolution. Here, we describe select phage small proteins that mediate phage-bacterial interactions by modulating phage lifestyle decision-making components or by altering host gene expression., Competing Interests: Declaration of Competing Interest The authors declare they have no competing interests., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2024
- Full Text
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