1,680 results on '"Bas, M."'
Search Results
2. Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum
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Andrzejczyk, Karolina, Abou Kamar, Sabrina, van Ommen, Anne-Mar, Canto, Elisa Dal, Petersen, Teun B., Valstar, Gideon, Akkerhuis, K. Martijn, Cramer, Maarten Jan, Umans, Victor, Rutten, Frans H., Teske, Arco, Boersma, Eric, Menken, Roxana, van Dalen, Bas M., Hofstra, Leonard, Verhaar, Marianne, Brugts, Jasper, Asselbergs, Folkert, den Ruijter, Hester, and Kardys, Isabella
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- 2024
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3. Identifying plasma proteomic signatures from health to heart failure, across the ejection fraction spectrum
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Karolina Andrzejczyk, Sabrina Abou Kamar, Anne-Mar van Ommen, Elisa Dal Canto, Teun B. Petersen, Gideon Valstar, K. Martijn Akkerhuis, Maarten Jan Cramer, Victor Umans, Frans H. Rutten, Arco Teske, Eric Boersma, Roxana Menken, Bas M. van Dalen, Leonard Hofstra, Marianne Verhaar, Jasper Brugts, Folkert Asselbergs, Hester den Ruijter, and Isabella Kardys
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Heart failure ,HFpEF ,HFrEF ,Biomarkers ,Proteomics ,Medicine ,Science - Abstract
Abstract Circulating proteins may provide insights into the varying biological mechanisms involved in heart failure (HF) with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF). We aimed to identify specific proteomic patterns for HF, by comparing proteomic profiles across the ejection fraction spectrum. We investigated 4210 circulating proteins in 739 patients with normal (Stage A/Healthy) or elevated (Stage B) filling pressures, HFpEF, or ischemic HFrEF (iHFrEF). We found 2122 differentially expressed proteins between iHFrEF-Stage A/Healthy, 1462 between iHFrEF–HFpEF and 52 between HFpEF-Stage A/Healthy. Of these 52 proteins, 50 were also found in iHFrEF vs. Stage A/Healthy, leaving SLITRK6 and NELL2 expressed in lower levels only in HFpEF. Moreover, 108 proteins, linked to regulation of cell fate commitment, differed only between iHFrEF–HFpEF. Proteomics across the HF spectrum reveals overlap in differentially expressed proteins compared to stage A/Healthy. Multiple proteins are unique for distinguishing iHFrEF from HFpEF, supporting the capacity of proteomics to discern between these conditions.
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- 2024
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4. Real-time parameter updating for nonlinear digital twins using inverse mapping models and transient-based features
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Kessels, Bas M., Fey, Rob H. B., and van de Wouw, Nathan
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- 2023
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5. Pulmonary Computed Tomography Screening Frequency in Primary Antibody Deficiency
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Smits, Bas M., Boland, Sharisa L., Hol, Marjolein E., Dandis, Rana, Leavis, Helen L., de Jong, Pim A., Prevaes, Sabine M.P.J., Mohamed Hoesein, Firdaus A.A., van Montfrans, Joris M., and Ellerbroek, Pauline M.
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- 2024
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6. Echocardiographic follow-up after cardiac rehabilitation designed for patients with obesity
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Snelder, Sanne M., den Uijl, Iris, Sunamura, Madoka, Zijlstra, Felix, ter Hoeve, Nienke, and van Dalen, Bas M.
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- 2023
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7. Decreased left atrial function in obesity patients without known cardiovascular disease
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Aga, Y. S., Kroon, D., Snelder, S. M., Biter, L. U., de Groot-de Laat, L. E., Zijlstra, F., Brugts, J. J., and van Dalen, Bas M.
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- 2023
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8. Potential role of left atrial strain in estimation of left atrial pressure in patients with chronic heart failure
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Yaar S. Aga, Sabrina Abou Kamar, Jie Fen Chin, Victor. J. van denBerg, Mihai Strachinaru, Daniel Bowen, Rene Frowijn, Martijn K. Akkerhuis, Alina A. Constantinescu, Victor Umans, Marcel L. Geleijnse, Eric Boersma, Jasper J. Brugts, Isabella Kardys, and Bas M. vanDalen
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Heart failure with reduced ejection fraction ,Left atrial strain ,Left atrial pressure ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims In a large proportion of heart failure with reduced ejection fraction (HFrEF) patients, echocardiographic estimation of left atrial pressure (LAP) is not possible when the ratio of the peak early left ventricular filling velocity over the late filling velocity (E/A ratio) is not available, which may occur due to several potential causes. Left atrial reservoir strain (LASr) is correlated with LV filling pressures and may serve as an alternative parameter in these patients. The aim of this study was to determine whether LASr can be used to estimate LAP in HFrEF patients in whom E/A ratio is not available. Methods and results Echocardiograms of chronic HFrEF patients were analysed and LASr was assessed with speckle tracking echocardiography. LAP was estimated using the current ASE/EACVI algorithm. Patients were divided into those in whom LAP could be estimated using this algorithm (LAPe) and into those in whom this was not possible because E/A ratio was not available (LAPne). We assessed the prognostic value of LASr on the primary endpoint (PEP), which comprised the composite of hospitalization for the management of acute or worsened HF, left ventricular assist device implantation, cardiac transplantation, and cardiovascular death, whichever occurred first in time. We studied 153 patients with a mean age of 58 years of whom 76% men and 82% who were in NYHA class I‐II. A total of 86 were in the LAPe group and 67 in the LAPne group. LASr was significantly lower in the LAPne group as compared with the LAPe group (15.8% vs. 23.8%, P
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- 2023
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9. Cardiac Surgery in Jehovah's Witnesses: 329 Consecutive Cases
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Langstraat, Mandy, Megens-Bastiaanse, Carla M., Rettig, Thijs C.D., Scohy, Thierry V., and Gerritse, Bas M.
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- 2023
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10. Normalization of Cardiac Function After Bariatric Surgery Is Related to Autonomic Function and Vitamin D
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Snelder, Sanne M., Aga, Yaar, de Groot - de Laat, Lotte E., Biter, L. Ulas, Cabezas, Manuel Castro, Pouw, Nadine, Birnie, Erwin, Boxma - de Klerk, Bianca, Klaassen, René A., Zijlstra, Felix, and van Dalen, Bas M.
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- 2023
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11. Model Updating for Nonlinear Dynamic Digital Twins Using Data-Based Inverse Mapping Models
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Kessels, Bas M., Fey, Rob H. B., Abbasi, Mohammad H., Wouw, Nathan van de, Madarshahian, Ramin, editor, and Hemez, Francois, editor
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- 2022
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12. Effect of bariatric surgery on NAFLD/NASH: a single-centre observational prospective cohort study
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Manuel Castro Cabezas, Bas M van Dalen, Diederick E Grobbee, Ellen M van der Zwan, Jan A Apers, Robert J de Knegt, Danny A Kanhai, Willy B Theel, Bianca M Boxma-de Klerk, Femme Dirksmeier-Harinck, Elisabeth FC van Rossum, Bojou Neecke, Thomas Hankemeier, and Janneke Wiebolt
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Medicine - Abstract
Introduction The prevalence of non-alcoholic fatty liver disease (NAFLD) ranges from 25% in the general population to 90% in patients with obesity scheduled for bariatric surgery. NAFLD can progress towards non-alcoholic steatohepatitis (NASH) associated with complications such as cirrhosis, hepatocellular carcinoma and cardiovascular disease. To date, losing weight and lifestyle modifications are the best known treatments for NASH. Bariatric surgery significantly improves NAFLD/NASH in the short term. However, the extent of this improvement is not yet clear and long-term data on the natural course of NAFLD/NASH after bariatric surgery are lacking. The factors involved in NAFLD/NASH regression after bariatric surgery have not been elucidated.Methods and analysis This is an observational prospective cohort study including patients scheduled for bariatric surgery. Extensive metabolic and cardiovascular analyses will be carried out including measurements of carotid intima media thickness and pulse wave velocity. Genomic, proteomic, lipidomic and metabolomic studies will be done. Microbioma analyses before and 1 year after surgery will be done. Transient elastography measurements will be performed before and at 1, 3 and 5 years after surgery. For those with an elevated preoperative transient elastography measurement by Fibroscan, a laparoscopic liver biopsy will be performed during surgery. Primary outcome measures are the change of steatosis and liver fibrosis 5 years after surgery. Secondary outcome measure is the comparison of the transient elastography measurements with the NAFLD Activity Score from the biopsies.Ethics and dissemination The protocol has been approved by the Medical Research Ethics Committees United, Nieuwegein, on 1 March 2022 (registration code R21.103/NL79423.100.21). The study results will be submitted for publication in peer-reviewed journals and data will be presented at scientific meetings.Trial registration number NCT05499949.
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- 2023
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13. Prognostic value of temporal patterns of global longitudinal strain in patients with chronic heart failure
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Sabrina Abou Kamar, Yaar S. Aga, Marie de Bakker, Victor J. van den Berg, Mihai Strachinaru, Dan Bowen, René Frowijn, K. Martijn Akkerhuis, Jasper Brugts, Olivier Manintveld, Victor Umans, Marcel L. Geleijnse, Eric Boersma, Bas M. van Dalen, and Isabella Kardys
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global longitudinal strain ,left ventricle ejection fraction ,heart failure ,repeated measurements ,longitudinal studies ,NT-proBNP ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
BackgroundWe investigated whether repeatedly measured global longitudinal strain (GLS) has incremental prognostic value over repeatedly measured left ventricular ejection fraction (LVEF) and N-terminal pro B-type natriuretic peptide (NT-proBNP), and a single “baseline” GLS value, in chronic heart failure (HF) patients.MethodsIn this prospective observational study, echocardiography was performed in 173 clinically stable chronic HF patients every six months during follow up. During a median follow-up of 2.7 years, a median of 3 (25th–75th percentile:2–4) echocardiograms were obtained per patient. The endpoint was a composite of HF hospitalization, left ventricular assist device, heart transplantation, cardiovascular death. We compared hazard ratios (HRs) for the endpoint from Cox models (used to analyze the first available GLS measurements) with HRs from joint models (which links repeated measurements to the time-to-event data).ResultsMean age was 58 ± 11 years, 76% were men, 81% were in New York Heart Association functional class I/II, and all had LVEF < 50% (mean ± SD: 27 ± 9%). The endpoint was reached by 53 patients. GLS was persistently decreased over time in patients with the endpoint. However, temporal GLS trajectories did not further diverge in patients with versus without the endpoint and remained stable during follow-up. Both single measurements and temporal trajectories of GLS were significantly associated with the endpoint [HR per SD change (95%CI): 2.15(1.34–3.46), 3.54 (2.01–6.20)]. In a multivariable model, repeatedly measured GLS maintained its prognostic value while repeatedly measured LVEF did not [HR per SD change (95%CI): GLS:4.38 (1.49–14.70), LVEF:1.14 (0.41–3.23)]. The association disappeared when correcting for repeatedly measured NT-proBNP.ConclusionTemporal evolution of GLS was associated with adverse events, independent of LVEF but not independent of NT-proBNP. Since GLS showed decreased but stable values in patients with adverse prognosis, single measurements of GLS provide sufficient information for determining prognosis in clinical practice compared to repeated measurements, and temporal GLS patterns do not add prognostic information to NT-proBNP.
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- 2023
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14. Short-term Mortality and Postoperative Complications of Abdominal Aortic Aneurysm Repair in Obese versus Non-obese Patients
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Bo Zonneveld, Duyen Vu, Isabella Kardys, Bas M van Dalen, and Sanne M Snelder
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obesity ,abdominal aortic aneurysm ,postoperative complications ,mortality ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Background : Obesity is a risk factor not only for abdominal aortic aneurysm (AAA) but also for complications after vascular surgery. This study was to determine the effect of obesity on short-term mortality and post-intervention complications after AAA repair. Methods : A systematic review and meta-analysis were performed. A systematic search was performed in PubMed; the articles describing the differences in post-intervention complications after open or endovascular repair of an AAA between obese and non-obese patients were selected. The primary outcome was short-term mortality defined as in-hospital mortality or mortality within 30 days after AAA repair. The secondary outcomes were cardiac complications, pulmonary failure, renal failure, and wound infections. The meta-analysis was performed using OpenMeta. Results : Four articles were included in the meta-analysis; these articles included 35,989 patients of which 10,917 (30.3%) were obese. The meta-analysis showed no significant differences for short-term mortality (odds ratio [OR], 0.85; 95% confidence interval [CI], 0.69-1.04). Also, no significant difference was found in pulmonary failure (OR, 1.09; 95% CI, 0.85-1.42). However, obese patients were less likely to suffer from cardiac complications (OR, 0.73; 95% CI, 0.55-0.96). Nevertheless, there was a significantly higher risk of renal failure (OR, 1.16; 95% CI, 1.05-1.30) and wound infections (OR, 1.92; 95% CI, 1.55-2.38) in obese patients. Conclusion : Obesity is not a risk factor for short-term mortality after AAA repair compared to non-obesity. Moreover, obese patients suffer less from cardiac complications than non-obese patients.
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- 2021
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15. Contemporary guideline‐directed medical therapy in de novo, chronic, and worsening heart failure patients: First data from the TITRATE‐HF study
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Malgie, Jishnu, primary, Wilde, Mariëlle I., additional, Clephas, Pascal R.D., additional, Emans, Mireille E., additional, Koudstaal, Stefan, additional, Schaap, Jeroen, additional, Mosterd, Arend, additional, van Ramshorst, Jan, additional, Wardeh, Alexander J., additional, van Wijk, Sandra, additional, van den Heuvel, Mieke, additional, Wierda, Eric, additional, Borleffs, C. Jan Willem, additional, Saraber, Colette, additional, Beeres, Saskia L.M.A., additional, van Kimmenade, Roland, additional, Jansen Klomp, Wouter, additional, Denham, Robert, additional, da Fonseca, Carlos A., additional, Klip, IJsbrand T., additional, Manintveld, Olivier C., additional, van der Boon, Robert M.A., additional, van Ofwegen, Clara E.E., additional, Yilmaz, Ayten, additional, Pisters, Ron, additional, Linssen, Gerard C.M., additional, Faber, Nikola, additional, van Heerebeek, Loek, additional, van de Swaluw, Julio E.C., additional, Bouhuijzen, Lex J., additional, Post, Marco C., additional, Kuijper, Aaf F.M., additional, Wu, Ka wai, additional, van Beek, Eugène A., additional, Hesselink, Tim, additional, Kleijn, Lennaert, additional, Kurvers, Maurice J.M., additional, Tio, René A., additional, Langerveld, Jorina, additional, van Dalen, Bas M., additional, van Eck, J.W. Martijn, additional, Handoko, M. Louis, additional, Hermans, Walter R.M., additional, Koornstra‐Wortel, Hetty J.J., additional, Szymanski, Mariusz K., additional, Rooker, Dennis, additional, Tandjung, Kenneth, additional, Eijsbouts, Sabine C.M., additional, Asselbergs, Folkert W., additional, van der Meer, Peter, additional, Brunner‐La Rocca, Hans‐Peter, additional, de Boer, Rudolf A., additional, and Brugts, Jasper J., additional
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- 2024
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16. Clinical outcomes after primary repair for thumb ulnar collateral ligament ruptures: a systematic review and meta-analysis
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Legerstee, Ingmar W. F., primary, Derksen, Bas M., additional, van der Oest, Mark J. W., additional, Hundepool, Caroline A., additional, Duraku, Liron S., additional, Selles, Ruud. W., additional, and Michiel Zuidam, J., additional
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- 2024
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17. Cardiac Function Normalizes 1 Year After Bariatric Surgery in Half of the Obesity Patients with Subclinical Cardiac Dysfunction
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Snelder, Sanne M., Aga, Yaar, de Groot-de Laat, Lotte E., Biter, L. Ulas, Castro Cabezas, Manuel, Pouw, Nadine, Boxma - de Klerk, Bianca M., Klaassen, René A., Zijlstra, Felix, and van Dalen, Bas M.
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- 2021
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18. Heterozygous Variants in the DNA-binding Domain of c-Myb May Affect Normal B/T Cell Development
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Bas M. Smits, Taila Hartley, Ester Dünnebach, Marije Bartels, Kim M. Boycott, Kirstin D. Kernohan, David A. Dyment, Jacques C. Giltay, Elie Haddad, Olga Jarinova, Joris van Montfrans, Annet van Royen-Kerkhof, Lars T. van der Veken, Moniek de Witte, Stefan Nierkens, Anne Pham-Huy, and Helen L. Leavis
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Diseases of the blood and blood-forming organs ,RC633-647.5 - Published
- 2022
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19. A Minimal Parameter Set Facilitating Early Decision-making in the Diagnosis of Hemophagocytic Lymphohistiocytosis
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Smits, Bas M., van Montfrans, Joris, Merrill, Samuel A., van de Corput, Lisette, van Gijn, Mariëlle, de Vries, Andrica, van den Bos, Cor, Abbink, Floor, van der Molen, Renate G., Dors, Natasja, Lindemans, Caroline, Boelens, Jaap J., and Nierkens, Stefan
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- 2021
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20. Pulmonary Computed Tomography Screening Frequency in Primary Antibody Deficiency
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Immuno/reuma onderzoek 1 (Vastert), Immuno/reuma onderzoek 7 (Montfrans), Infection & Immunity, MS Radiologie, MS Reumatologie/Immunologie/Infectie, Researchgr. Systems Radiology, Cancer, Circulatory Health, Regenerative Medicine and Stem Cells, Longziekten patientenzorg, Cluster B, Immuno/reuma patientenzorg, Child Health, MS Interne Geneeskunde, Smits, Bas M, Boland, Sharisa L, Hol, Marjolein E, Dandis, Rana, Leavis, Helen, de Jong, Pim A, Prevaes, Sabine M P J, Mohamed Hoesein, Firdaus A A, van Montfrans, Joris M, Ellerbroek, Pauline M, Immuno/reuma onderzoek 1 (Vastert), Immuno/reuma onderzoek 7 (Montfrans), Infection & Immunity, MS Radiologie, MS Reumatologie/Immunologie/Infectie, Researchgr. Systems Radiology, Cancer, Circulatory Health, Regenerative Medicine and Stem Cells, Longziekten patientenzorg, Cluster B, Immuno/reuma patientenzorg, Child Health, MS Interne Geneeskunde, Smits, Bas M, Boland, Sharisa L, Hol, Marjolein E, Dandis, Rana, Leavis, Helen, de Jong, Pim A, Prevaes, Sabine M P J, Mohamed Hoesein, Firdaus A A, van Montfrans, Joris M, and Ellerbroek, Pauline M
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- 2024
21. Subclinical cardiac dysfunction in obesity patients is linked to autonomic dysfunction: findings from the CARDIOBESE study
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Sanne M. Snelder, Lotte E. deGroot‐de Laat, L. Ulas Biter, Manuel Castro Cabezas, Nadine Pouw, Erwin Birnie, Bianca M. Boxma‐de Klerk, René A. Klaassen, Felix Zijlstra, and Bas M. vanDalen
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Obesity/obese ,Cardiac dysfunction ,Global longitudinal strain ,Speckle‐tracking echocardiography ,Heart rate variability ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims Obesity doubles the lifetime risk of developing heart failure. Current knowledge on the role of obesity in causing cardiac dysfunction is insufficient for optimal risk stratification. The aim of this study was first to estimate the prevalence of subclinical cardiac dysfunction in obesity patients and second to investigate the underlying pathophysiology. Methods and results The CARDIOBESE study is a cross‐sectional multicentre study of 100 obesity patients [body mass index (BMI) ≥ 35 kg/m2] without known cardiovascular disease and 50 age‐matched and gender‐matched non‐obese controls (BMI ≤ 30 kg/m2). Echocardiography was performed, blood samples were collected, and a Holter monitor was affixed. Fifty‐nine obesity patients [48 (42–50) years, 70% female] showed subclinical cardiac dysfunction: 57 patients had decreased global longitudinal strain (GLS), and two patients with normal GLS had either diastolic dysfunction or increased brain natriuretic peptide (BNP). Only one non‐obese control had diastolic dysfunction, and none had another sign of cardiac dysfunction. Multivariable logistic analysis identified male gender and standard deviation of all NN intervals (SDNN) index, which is a measure of autonomic dysfunction, as independent significant risk factors for subclinical cardiac dysfunction in obesity patients. Conclusions There was a high prevalence (61%) of subclinical cardiac dysfunction in obesity patients without known cardiovascular disease, which appeared to be best identified by GLS. Subclinical cardiac dysfunction in obesity was linked to autonomic dysfunction and male gender, and not to the presence of traditional cardiac risk factors, increased C‐reactive protein, increased BNP, increased high‐sensitivity troponin I, or increased left ventricular mass.
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- 2020
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22. Three-dimensional QCA-based vessel fractional flow reserve (vFFR) in Heart Team decision-making: a multicentre, retrospective, cohort study
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Felix Zijlstra, Bas M van Dalen, Joost Daemen, Nicolas M Van Mieghem, Roberto Diletti, Nick van Boven, Isabella Kardys, Mariusz Tomaniak, Kaneshka Masdjedi, Tara Neleman, Ibrahim T Kucuk, Alise Vermaire, Laurens J C van Zandvoort, Loe Kie Soei, Wijnand K den Dekker, and Jeroen M Wilschut
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Medicine - Abstract
Objectives To evaluate the feasibility of three-vessel three-dimensional (3D) quantitative coronary angiography (QCA)-based fractional flow reserve (FFR) computation in patients discussed within the Heart Team in whom the treatment decision was based on angiography alone, and to evaluate the concordance between 3D QCA-based vessel FFR (vFFR)-confirmed functional lesion significance and revascularisation strategy as proposed by the Heart Team.Design Retrospective, cohort.Setting 3D QCA-based FFR indices have not yet been evaluated in the context of Heart Team decision-making; consecutive patients from six institutions were screened for eligibility and three-vessel vFFR was computed by blinded analysts.Participants Consecutive patients with chronic coronary syndrome or unstable angina referred for Heart Team consultation. Exclusion criteria involved: presentation with acute myocardial infarction (MI), significant valve disease, left ventricle ejection fraction
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- 2022
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23. Diseño de un conjunto de indicadores sobre recomendaciones de «No Hacer»
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José Blázquez Álvarez, M., Farmacia, S., Pilar Ferrer Bas, M., Calidad Enfermería, A., García Gambín, Francisco, Evaluación, S., Pérez Ayala, Millán, Análisis Clínicos, S., Picazo Córdoba, Román, Documentación Clínica, S., Vera Guirao, Juan J., Informática, S., Moreno López, A.B., and López-Picazo Ferrer, J.J.
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- 2020
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24. Obesity and cardiovascular disease: how to solve a puzzle with so many interlocking pieces?
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van Dalen, Bas M, primary and Chin, Jie Fen, additional
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- 2024
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25. Refraining from closed reduction of displaced distal radius fractures in the emergency department – in short: the RECORDED trial
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Derksen, Bas M, primary, Jawahier, Priscilla A, additional, Wijers, Olivier, additional, Knops, Simon P, additional, de Vries, Mark R, additional, Hooff, Christiaan C Drijfhout van, additional, Verhofstad, Michiel H J, additional, and Schep, Niels W L, additional
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- 2024
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26. Immunoglobulin Replacement Therapy Versus Antibiotic Prophylaxis as Treatment for Incomplete Primary Antibody Deficiency
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Smits, Bas M., Kleine Budde, Ilona, de Vries, Esther, ten Berge, Ineke J. M., Bredius, Robbert G. M., van Deuren, Marcel, van Dissel, Jaap T., Ellerbroek, Pauline M., van der Flier, Michiel, van Hagen, P. Martin, Nieuwhof, Chris, Rutgers, Bram, Sanders, Lieke E. A. M., Simon, Anna, Kuijpers, Taco W., and van Montfrans, Joris M.
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- 2021
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27. Left atrial strain by three-dimensional speckle tracking echocardiography: The long road to establishment for a nouveau arrive
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van Dalen, Bas M., Aga, Yaar S., and van der Zwaan, Heleen B.
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- 2022
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28. Subgenomic flavivirus RNA binds the mosquito DEAD/H-box helicase ME31B and determines Zika virus transmission by Aedes aegypti
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Göertz, Giel P., van Bree, Joyce W. M., Hiralal, Anwar, Fernhout, Bas M., Steffens, Carmen, Boeren, Sjef, Visser, Tessa M., Vogels, Chantal B. F., Abbo, Sandra R., Fros, Jelke J., Koenraadt, Constantianus J. M., van Oers, Monique M., and Pijlman, Gorben P.
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- 2019
29. Physical model of scour at the toe of rock armoured structures
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den Bieman, Joost P., van Gent, Marcel R.A., and Hoonhout, Bas M.
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- 2019
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30. Naturally Occurring Shear Waves in Healthy Volunteers and Hypertrophic Cardiomyopathy Patients
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Strachinaru, Mihai, Bosch, Johan G., van Gils, Lennart, van Dalen, Bas M., Schinkel, Arend F.L., van der Steen, Antonius F.W., de Jong, Nico, Michels, Michelle, Vos, Hendrik J., and Geleijnse, Marcel L.
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- 2019
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31. Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial
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Abdelhamid, N, Abdul Rahman, D, Abdul-Saheb, M, Abreu, P, Abroskina, M, Abu Ahmad, F, Accassat, S, Acciaresi, M, Adami, A, Ahmad, N, Ahmed, F, Alberto Hawkes, M, Alemseged, F, Ali, A, Altavilla, R, Alwis, L, Amarenco, P, Amaro, S, Amaya Sanchez, LE, Amelia Pinto, A, Ameriso, SF, Amin, H, Amino, T, Amjad, AK, Anagnostou, E, Andersen, G, Anderson, C, Anderson, DC, Andrea Falco, M, Andres Mackinnon, F, Andreu, D, Androulakis, M, Angel Gamero, M, Angel Saredo, G, Angeles Diaz, R, Angels Font, M, Anticoli, S, Arauz, A, Arauz Gongora, AA, Araya, P, Arenillas Lara, JF, Arias Rivas, S, Arnold, M, Augustin, S, Avelar, W, Azevedo, E, Babikian, V, Bacellar, A, Badalyan, K, Bae, HJ, Baez Martinez, EM, Bagelmann, H, Bailey, P, Bak, Z, Baker, M, Balazs, A, Baldaranov, D, Balogun, I, Balueva, T, Bankuti, Z, Bar, M, Baranowska, A, Bardutzky, J, Barker Trejo, S, Barlinn, J, Baronnet, F, Barroso, C, Barteys, M, Bartolottiova, T, Barulin, A, Bas, M, Bashir, S, Basile, V, Bathe-Peters, R, Bathula, R, 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32. Acute perimyocarditis associated withBartonella henselaeinfection
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Cucchi, David GJ, primary, Govers, Annebel, additional, Janse, Frank H, additional, and van Dalen, Bas M, additional
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- 2023
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33. Mutual information-based feature selection for inverse mapping parameter updating of dynamical systems
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Kessels, Bas M., primary, Fey, Rob H. B., additional, and de Wouw, Nathan van, additional
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- 2023
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34. Decreased left atrial function in obesity patients without known cardiovascular disease
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Y. S. Aga, D. Kroon, S. M. Snelder, L. U. Biter, L. E. de Groot-de Laat, F. Zijlstra, J. J. Brugts, Bas M. van Dalen, Cardiology, and Orthopedics and Sports Medicine
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SDG 3 - Good Health and Well-being - Abstract
Obesity is a risk factor for heart failure with preserved ejection fraction (HFpEF). We hypothesized that assessment of left atrial (LA) strain may be useful to reveal precursors of HFpEF in obesity patients. Echocardiograms of obesity patients without known cardiovascular disease who underwent bariatric surgery, and echocardiograms of age- and gender matched controls were analyzed. The echocardiogram was repeated 1 year after bariatric surgery. LA reservoir strain (LASr), LA conduit strain (LAScd), and LA contractile strain (LASct) were measured. 77 Obesity patients were compared with 46 non-obese controls. Obesity patients showed a significantly decreased LA function compared with non-obese individuals (LASr 32.2% ± 8.8% vs. 39.6% ± 10.8%, p
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- 2023
35. Treatment Strategies for GLILD in Common Variable Immunodeficiency: A Systematic Review
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Olivia A. C. Lamers, Bas M. Smits, Helen Louisa Leavis, Godelieve J. de Bree, Charlotte Cunningham-Rundles, Virgil A. S. H. Dalm, Hsi-en Ho, John R. Hurst, Hanna IJspeert, Sabine M. P. J. Prevaes, Alex Robinson, Astrid C. van Stigt, Suzanne Terheggen-Lagro, Annick A. J. M. van de Ven, Klaus Warnatz, Janneke H. H. M. van de Wijgert, and Joris van Montfrans
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systematic review ,immunodeficiency ,common variable immunodeficiency ,CVID ,granulomatous lymphocytic interstitial lung disease ,GLILD ,Immunologic diseases. Allergy ,RC581-607 - Abstract
IntroductionBesides recurrent infections, a proportion of patients with Common Variable Immunodeficiency Disorders (CVID) may suffer from immune dysregulation such as granulomatous-lymphocytic interstitial lung disease (GLILD). The optimal treatment of this complication is currently unknown. Experienced-based expert opinions have been produced, but a systematic review of published treatment studies is lacking.GoalsTo summarize and synthesize the published literature on the efficacy of treatments for GLILD in CVID.MethodsWe performed a systematic review using the PRISMA guidelines. Papers describing treatment and outcomes in CVID patients with radiographic and/or histologic evidence of GLILD were included. Treatment regimens and outcomes of treatment were summarized.Results6124 papers were identified and 42, reporting information about 233 patients in total, were included for review. These papers described case series or small, uncontrolled studies of monotherapy with glucocorticoids or other immunosuppressants, rituximab monotherapy or rituximab plus azathioprine, abatacept, or hematopoietic stem cell transplantation (HSCT). Treatment response rates varied widely. Cross-study comparisons were complicated because different treatment regimens, follow-up periods, and outcome measures were used. There was a trend towards more frequent GLILD relapses in patients treated with corticosteroid monotherapy when compared to rituximab-containing treatment regimens based on qualitative endpoints. HSCT is a promising alternative to pharmacological treatment of GLILD, because it has the potential to not only contain symptoms, but also to resolve the underlying pathology. However, mortality, especially among immunocompromised patients, is high.ConclusionsWe could not draw definitive conclusions regarding optimal pharmacological treatment for GLILD in CVID from the current literature since quantitative, well-controlled evidence was lacking. While HSCT might be considered a treatment option for GLILD in CVID, the risks related to the procedure are high. Our findings highlight the need for further research with uniform, objective and quantifiable endpoints. This should include international registries with standardized data collection including regular pulmonary function tests (with carbon monoxide-diffusion), uniform high-resolution chest CT radiographic scoring, and uniform treatment regimens, to facilitate comparison of treatment outcomes and ultimately randomized clinical trials.
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- 2021
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36. Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model
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Westeneng, Henk-Jan, Debray, Thomas P A, Visser, Anne E, van Eijk, Ruben P A, Rooney, James P K, Calvo, Andrea, Martin, Sarah, McDermott, Christopher J, Thompson, Alexander G, Pinto, Susana, Kobeleva, Xenia, Rosenbohm, Angela, Stubendorff, Beatrice, Sommer, Helma, Middelkoop, Bas M, Dekker, Annelot M, van Vugt, Joke J F A, van Rheenen, Wouter, Vajda, Alice, Heverin, Mark, Kazoka, Mbombe, Hollinger, Hannah, Gromicho, Marta, Körner, Sonja, Ringer, Thomas M, Rödiger, Annekathrin, Gunkel, Anne, Shaw, Christopher E, Bredenoord, Annelien L, van Es, Michael A, Corcia, Philippe, Couratier, Philippe, Weber, Markus, Grosskreutz, Julian, Ludolph, Albert C, Petri, Susanne, de Carvalho, Mamede, Van Damme, Philip, Talbot, Kevin, Turner, Martin R, Shaw, Pamela J, Al-Chalabi, Ammar, Chiò, Adriano, Hardiman, Orla, Moons, Karel G M, Veldink, Jan H, and van den Berg, Leonard H
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- 2018
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37. What Works When Treating Granulomatous Disease in Genetically Undefined CVID? A Systematic Review
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Astrid C. van Stigt, Willem A. Dik, Lieke S. J. Kamphuis, Bas M. Smits, Joris M. van Montfrans, P. Martin van Hagen, Virgil A. S. H. Dalm, and Hanna IJspeert
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common variable immune deficiency ,granulomatous disease ,lung ,immunosuppressive therapy ,extrapulmonary ,Immunologic diseases. Allergy ,RC581-607 - Abstract
BackgroundGranulomatous disease is reported in at least 8–20% of patients with common variable immunodeficiency (CVID). Granulomatous disease mainly affects the lungs, and is associated with significantly higher morbidity and mortality. In half of patients with granulomatous disease, extrapulmonary manifestations are found, affecting e.g. skin, liver, and lymph nodes. In literature various therapies have been reported, with varying effects on remission of granulomas and related clinical symptoms. However, consensus recommendations for optimal management of extrapulmonary granulomatous disease are lacking.ObjectiveTo present a literature overview of the efficacy of currently described therapies for extrapulmonary granulomatous disease in CVID (CVID+EGD), compared to known treatment regimens for pulmonary granulomatous disease in CVID (CVID+PGD).MethodsThe following databases were searched: Embase, Medline (Ovid), Web-of-Science Core Collection, Cochrane Central, and Google Scholar. Inclusion criteria were 1) CVID patients with granulomatous disease, 2) treatment for granulomatous disease reported, and 3) outcome of treatment reported. Patient characteristics, localization of granuloma, treatment, and association with remission of granulomatous disease were extracted from articles.ResultsWe identified 64 articles presenting 95 CVID patients with granulomatous disease, wherein 117 different treatment courses were described. Steroid monotherapy was most frequently described in CVID+EGD (21 out of 53 treatment courses) and resulted in remission in 85.7% of cases. In CVID+PGD steroid monotherapy was described in 15 out of 64 treatment courses, and was associated with remission in 66.7% of cases. Infliximab was reported in CVID+EGD in six out of 53 treatment courses and was mostly used in granulomatous disease affecting the skin (four out of six cases). All patients (n = 9) treated with anti-TNF-α therapies (infliximab and etanercept) showed remission of extrapulmonary granulomatous disease. Rituximab with or without azathioprine was rarely used for CVID+EGD, but frequently used in CVID+PGD where it was associated with remission of granulomatous disease in 94.4% (17 of 18 treatment courses).ConclusionAlthough the number of CVID+EGD patients was limited, data indicate that steroid monotherapy often results in remission, and that anti-TNF-α treatment is effective for granulomatous disease affecting the skin. Also, rituximab with or without azathioprine was mainly described in CVID+PGD, and only in few cases of CVID+EGD.
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- 2020
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38. Characterization of heterotrophic growth and sesquiterpene production by Rhodobacter sphaeroides on a defined medium
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Orsi, Enrico, Folch, Pauline L., Monje-López, Vicente T., Fernhout, Bas M., Turcato, Alessandro, Kengen, Servé W. M., Eggink, Gerrit, and Weusthuis, Ruud A.
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- 2019
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39. Normalization of Cardiac Function After Bariatric Surgery Is Related to Autonomic Function and Vitamin D
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Sanne M. Snelder, Yaar Aga, Lotte E. de Groot - de Laat, L. Ulas Biter, Manuel Castro Cabezas, Nadine Pouw, Erwin Birnie, Bianca Boxma - de Klerk, René A. Klaassen, Felix Zijlstra, Bas M. van Dalen, and Cardiology
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Nutrition and Dietetics ,SDG 3 - Good Health and Well-being ,Endocrinology, Diabetes and Metabolism ,Surgery - Abstract
Purpose Subclinical cardiac dysfunction is common in patients with obesity. Bariatric surgery is associated with normalization of subclinical cardiac function in 50% of the patients with obesity. The aim of this study was to identify predictors for a lack of improvement of subclinical cardiac dysfunction 1-year post-bariatric surgery. Methods Patients who were referred for bariatric surgery were enrolled in a longitudinal study. Inclusion criteria were age 35–65 years and BMI ≥ 35 kg/m2. Patients with a suspicion of or known cardiovascular disease were excluded. Conventional and advanced echocardiography, Holter monitoring, and blood tests were performed pre- and 1-year post-bariatric surgery. Subclinical cardiac dysfunction was defined as either a reduced left ventricular ejection fraction, decreased global longitudinal strain (GLS), diastolic dysfunction, arrhythmia, or an increased BNP or hs Troponin I. Results A total of 99 patients were included of whom 59 patients had cardiac dysfunction at baseline. Seventy-two patients completed the 1-year follow-up after bariatric surgery. There was a significant reduction in weight and cardiovascular risk factors. Parameters of cardiac function, such as GLS, improved. However, in 20 patients cardiac dysfunction persisted. Multivariate analysis identified a decreased heart rate variability (which is a measure of autonomic function), and a decreased vitamin D pre-surgery as predictors for subclinical cardiac dysfunction after bariatric surgery. Conclusion Although there was an overall improvement of cardiac function 1-year post-bariatric surgery, autonomic dysfunction and a decreased vitamin D pre-bariatric surgery were predictors for a lack of improvement of subclinical cardiac dysfunction. Graphical abstract
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- 2023
40. Cardiovascular Biomarker Profiles in Obesity and Relation to Normalization of Subclinical Cardiac Dysfunction after Bariatric Surgery
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Sanne M. Snelder, Nadine Pouw, Yaar Aga, Manuel Castro Cabezas, L. Ulas Biter, Felix Zijlstra, Isabella Kardys, and Bas M. van Dalen
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obesity/obese ,bariatric surgery ,cardiac dysfunction ,biomarkers ,Cytology ,QH573-671 - Abstract
Aims: We aimed to gain insight into the underlying pathophysiology of cardiac dysfunction in obesity patients and the improvement of cardiac function after weight loss. Methods: This is a longitudinal study in which 92 cardiovascular biomarkers were measured by multiplex immunoassays in obesity patients without known cardiovascular disease, before and one year after bariatric surgery. Results: Out of 100 eligible patients, 72 patients completed the follow-up. A total of 72 (78%) biomarkers changed significantly. The biomarkers with the highest relative changes represented processes linked mainly to insulin resistance and inflammation. In the patients with persistent subclinical cardiac dysfunction, the baseline values of 10 biomarkers were different from values in patients with normalization of cardiac function. Most of these biomarkers were linked to inflammation or atherosclerosis. Finally, a model was developed to investigate the relationship between changes in the biomarkers and persistent subclinical cardiac dysfunction. Seven biomarkers were retained in this model, mainly linked to inflammation, atherosclerosis, and hypercoagulability. Conclusion: The majority (78%) of cardiovascular biomarkers changed, pointing mainly to modulation of insulin resistance and inflammation. The baseline levels of 10 biomarkers, as well as pre- to post-bariatric surgery changes in seven biomarkers, were related to persistent subclinical cardiac dysfunction after bariatric surgery.
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- 2022
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41. Efficient switching of mCherry fluorescence using chemical caging
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Cloin, Bas M. C., De Zitter, Elke, Salas, Desiree, Gielen, Vincent, Folkers, Gert E., Mikhaylova, Marina, Bergeler, Maike, Krajnik, Bartosz, Harvey, Jeremy, Hoogenraad, Casper C., Van Meervelt, Luc, Dedecker, Peter, and Kapitein, Lukas C.
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- 2017
42. Effect of bariatric surgery on NAFLD/NASH: a single-centre observational prospective cohort study
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Theel, Willy B, primary, Boxma-de Klerk, Bianca M, additional, Dirksmeier-Harinck, Femme, additional, van Rossum, Elisabeth FC, additional, Kanhai, Danny A, additional, Apers, Jan A, additional, van Dalen, Bas M, additional, De Knegt, Robert J, additional, Neecke, Bojou, additional, van der Zwan, Ellen M, additional, Grobbee, Diederick E, additional, Hankemeier, Thomas, additional, Wiebolt, Janneke, additional, and Castro Cabezas, Manuel, additional
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- 2023
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43. Cardiac Shear Wave Elastography Using a Clinical Ultrasound System
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Strachinaru, Mihai, Bosch, Johan G., van Dalen, Bas M., van Gils, Lennart, van der Steen, Antonius F.W., de Jong, Nico, Geleijnse, Marcel L., and Vos, Hendrik J.
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- 2017
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44. Cardiac Shear Wave Velocity Detection in the Porcine Heart
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Vos, Hendrik J., van Dalen, Bas M., Heinonen, Ilkka, Bosch, Johan G., Sorop, Oana, Duncker, Dirk J., van der Steen, Antonius F.W., and de Jong, Nico
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- 2017
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45. Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement
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Heinonen, Ilkka, Sorop, Oana, van Dalen, Bas M., Wüst, Rob C. I., van de Wouw, Jens, de Beer, Vincent J., Octavia, Yanti, van Duin, Richard W. B., Hoogstrate, Youri, Blonden, Lau, Alkio, Milla, Anttila, Katja, Stubbs, Andrew, van der Velden, Jolanda, Merkus, Daphne, and Duncker, Dirk J.
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- 2020
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46. Atrial Septal Defect Mimicking Right Atrial Myxoma: Multimodality Imaging of Cardiac Mass
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van der Zwaan, Heleen B., Kirschbaum, Sharon W., Snelder, Sanne M., von der Thüsen, Jan, and van Dalen, Bas M.
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- 2020
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47. Heart failure treatment in patients with and without obesity with an ejection fraction below 50%
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Yaar S. Aga, Sumant P. Radhoe, Dilan Aydin, G. C. M. Linssen, Philip C. Rademaker, Peter R. Geerlings, Marco W. F. van Gent, Ismail Aksoy, Liane Oosterom, Hans‐Peter Brunner‐La Rocca, Bas M. van Dalen, Jasper J. Brugts, MUMC+: MA Cardiologie (3), RS: Carim - H02 Cardiomyopathy, Cardiologie, and MUMC+: MA Med Staf Spec Cardiologie (9)
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RISK ,obesity ,IMPACT ,Clinical Biochemistry ,heart failure ,General Medicine ,DIAGNOSIS ,Biochemistry ,MEDICAL THERAPY ,pharmacotherapy ,SDG 3 - Good Health and Well-being ,PARADOX ,ESC GUIDELINES ,guideline adherence ,METAANALYSIS - Abstract
Background: The aim of this study was to assess heart failure (HF) treatment in patients with and without obesity in a large contemporary real-world Western European cohort. Methods: Patients with a left ventricular ejection fraction (LVEF) 2 and ≥30 kg/m 2) was performed. Results: Seven thousand six hundred seventy-one patients were included, 1284 (16.7%) had a BMI ≥30 kg/m 2, and 618 (8.1%) had a BMI ≥35 kg/m 2. Median BMI was 26.4 kg/m 2. Patients with obesity were younger and had a higher rate of comorbidities such as diabetes mellitus, hypertension and obstructive sleep apnoea (OSAS). Prescription rates of guideline-directed medical therapy (GDMT) increased significantly with BMI. The differences were most pronounced for mineralocorticoid receptor antagonists (MRAs) and diuretics. Patients with obesity more often received the guideline-recommended target dose. In multivariable logistic regression, obesity was significantly associated with a higher likelihood of receiving ≥100% of the guideline-recommended target dose of beta-blockers (OR 1.34, 95% CI 1.10–1.62), renin–angiotensin system (RAS)-inhibitors (OR 1.34, 95% CI 1.15–1.57) and MRAs (OR 1.40, 95% CI 1.04–1.87). Conclusions: Guideline-recommended HF drugs are more frequently prescribed and at a higher dose in patients with obesity as compared to HF patients without obesity.
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- 2023
48. Real-time parameter updating for nonlinear digital twins using inverse mapping models and transient-based features
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Bas M. Kessels, Rob H. B. Fey, Nathan van de Wouw, Group Van de Wouw, Dynamics and Control, and Mechanical Engineering
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Model updating ,Control and Systems Engineering ,Applied Mathematics ,Mechanical Engineering ,Nonlinear systems ,Parameter estimation ,Aerospace Engineering ,Ocean Engineering ,Electrical and Electronic Engineering ,Transient-based features ,Digital twin ,Neural networks - Abstract
In the context of digital twins, it is essential that a model gives an accurate description of the (controlled) dynamic behavior of a physical system during the system’s entire operational life. Therefore, model updating techniques are required that enable real-time updating of physically interpretable parameter values and are applicable to a wide range of (nonlinear) dynamical systems. As traditional, iterative, parameter updating methods may be computationally too expensive for real-time updating, the inverse mapping parameter updating (IMPU) method is proposed as an alternative. For this method, first, an artificial neural network (ANN) is trained offline using novel features of simulated transient response data. Then, in the online phase, this ANN maps, with little computational cost, a set of measured output response features to parameter estimates enabling real-time model updating. In this paper, various types of transient response features are introduced to update parameter values of nonlinear dynamical systems with increased computational efficiency and accuracy. To analyze the efficacy of these features, the IMPU method is applied to a (simulated) nonlinear multibody system. It is shown that a smart selection of features, based on, e.g., the frequency content of the transient response, can improve the accuracy of the estimated parameter values, leading to more accurate updated models. Furthermore, the generalization capabilities of the ANNs are analyzed for these feature types, by varying the number of training samples and assessing the effect of incomplete training data. It is shown that the IMPU method can predict parameter values that are not part of the training data with acceptable accuracy as well.
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- 2023
49. A score for the differential diagnosis of bradykinin- and histamine-induced head and neck swellings
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Lenschow, M., Bas, M., Johnson, F., Wirth, M., and Strassen, U.
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- 2018
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50. Round-the-clock performance of coronary CT angiography for suspected acute coronary syndrome: Results from the BEACON trial
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Lubbers, Marisa M., Dedic, Admir, Kurata, Akira, Dijkshoorn, Marcel, Schaap, Jeroen, Lammers, Jeroen, Lamfers, Evert J., Rensing, Benno J., Braam, Richard L., Nathoe, Hendrik M., Post, Johannes C., Rood, Pleunie P., Schultz, Carl J., Moelker, Adriaan, Ouhlous, Mohamed, van Dalen, Bas M., Boersma, Eric, and Nieman, Koen
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- 2018
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