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2. Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022

Author

de Kleine, R, Lexmond, W, Buescher, G, Sturm, E, Kelly, D, Lohse, A, Lenz, D, Jorgensen, M, Protopapa, P, Shteyer, E, Iorio, R, Pukite, I, Kucinskiene, R, Grima, A, Koot, B, Pop, T, De Bruyne, R, Stephenne, Vukovic, J, Mitrova, K, Kvistgaard, H, Merras-Salmio, L, Hery, G, Debray, D, Ruiz, M, Schulz-Jurgensen, S, Lurz, E, Hives, V, Cananzi, M, D'Antiga, L, di Giorgio, A, Pinon, M, Kaminska, D, Costa, I, Brecelj, J, Bartolo, G, Quintero, J, Fischler, B, Mclin, V, de Kleine R. H., Lexmond W. S., Buescher G., Sturm E., Kelly D., Lohse A. W., Lenz D., Jorgensen M. H., Protopapa P., Shteyer E., Iorio R., Pukite I., Kucinskiene R., Grima A. -M., Koot B., Pop T. L., De Bruyne R., Vukovic J., Mitrova K., Kvistgaard H., Merras-Salmio L., Hery G., Debray D., Ruiz M., Schulz-Jurgensen S., Lurz E., Hives V., Cananzi M., D'Antiga L., di Giorgio A., Pinon M., Kaminska D., Costa I. G., Brecelj J., Bartolo G. M., Quintero J., Fischler B., McLin V., de Kleine, R, Lexmond, W, Buescher, G, Sturm, E, Kelly, D, Lohse, A, Lenz, D, Jorgensen, M, Protopapa, P, Shteyer, E, Iorio, R, Pukite, I, Kucinskiene, R, Grima, A, Koot, B, Pop, T, De Bruyne, R, Stephenne, Vukovic, J, Mitrova, K, Kvistgaard, H, Merras-Salmio, L, Hery, G, Debray, D, Ruiz, M, Schulz-Jurgensen, S, Lurz, E, Hives, V, Cananzi, M, D'Antiga, L, di Giorgio, A, Pinon, M, Kaminska, D, Costa, I, Brecelj, J, Bartolo, G, Quintero, J, Fischler, B, Mclin, V, de Kleine R. H., Lexmond W. S., Buescher G., Sturm E., Kelly D., Lohse A. W., Lenz D., Jorgensen M. H., Protopapa P., Shteyer E., Iorio R., Pukite I., Kucinskiene R., Grima A. -M., Koot B., Pop T. L., De Bruyne R., Vukovic J., Mitrova K., Kvistgaard H., Merras-Salmio L., Hery G., Debray D., Ruiz M., Schulz-Jurgensen S., Lurz E., Hives V., Cananzi M., D'Antiga L., di Giorgio A., Pinon M., Kaminska D., Costa I. G., Brecelj J., Bartolo G. M., Quintero J., Fischler B., and McLin V.

Abstract

To detect potential concern about severe acute hepatitis in children, we conducted a survey among 50 ERN RARE-LIVER centres. By 26 April 2022, 34 centres, including 25 transplant centres, reported an estimated median of 3-5, 0-2 and 3-5 cases in 2021, 2020 and 2019 and a mean of 2 (range: 0-8) cases between January and April 2022 (mean in 10 large liver transplant centres: 3). Twelve centres reported suspicion of an increase, but no rise. Following a report by the United Kingdom (UK) on 5 April 2022 on the occurrence of cases of severe acute hepatitis in children aged 16 years or under, the World Health Organization (WHO) raised concerns about the possibility of an epidemic [1,2]. By 21 April, 169 possible or confirmed cases were reported fulfilling the WHO case definition [3]. The cause of the hepatitis is unknown but a link to a virus infection has been suggested due to the epidemiological pattern of cases [4,5]. The hepatitis can progress to paediatric acute liver failure (pALF) necessitating urgent liver transplantation to avoid multi-organ failure [6]. We intended to assess whether a rise in incidence of severe acute hepatitis or pALF could be observed between 1 January and 26 April 2022 in comparison to previous years, within the European Reference Network on Hepatological Diseases (ERN RARE-LIVER) [7].

Published
2022

4. Current practices on diagnosis, prevention and treatment of post-transplant lymphoproliferative disorder in pediatric patients after solid organ transplantation: Results of ern transplantchild healthcareworking group survey

Author

Baker, A, Remacha, E, Canizales, J, Bravo-Gallego, L, Fitzpatrick, E, Melgar, A, Bartolo, G, Guereta, L, Boluda, E, Mozo, Y, Broniszczak, D, Jarmuzek, W, Kalicinski, P, Maecker-Kolhoff, B, Carlens, J, Baumann, U, Roy, C, Chardot, C, Benetti, E, Cananzi, M, Calore, E, Dello Strologo, L, Candusso, M, Lopes, M, Brito, M, Goncalves, C, Do Carmo, C, Stephenne, X, Wennberg, L, Stone, R, Rascon, J, Lindemans, C, Turkiewicz, D, Giraldi, E, Nicastro, E, D'Antiga, L, Ackermann, O, Vega, P, Baker A., Remacha E. F., Canizales J. T., Bravo-Gallego L. Y., Fitzpatrick E., Melgar A. A., Bartolo G. M., Guereta L. G., Boluda E. R., Mozo Y., Broniszczak D., Jarmuzek W., Kalicinski P., Maecker-Kolhoff B., Carlens J., Baumann U., Roy C., Chardot C., Benetti E., Cananzi M., Calore E., Dello Strologo L., Candusso M., Lopes M. F., Brito M. J., Goncalves C., Do Carmo C., Stephenne X., Wennberg L., Stone R., Rascon J., Lindemans C., Turkiewicz D., Giraldi E., Nicastro E., D'Antiga L., Ackermann O., Vega P. J., Baker, A, Remacha, E, Canizales, J, Bravo-Gallego, L, Fitzpatrick, E, Melgar, A, Bartolo, G, Guereta, L, Boluda, E, Mozo, Y, Broniszczak, D, Jarmuzek, W, Kalicinski, P, Maecker-Kolhoff, B, Carlens, J, Baumann, U, Roy, C, Chardot, C, Benetti, E, Cananzi, M, Calore, E, Dello Strologo, L, Candusso, M, Lopes, M, Brito, M, Goncalves, C, Do Carmo, C, Stephenne, X, Wennberg, L, Stone, R, Rascon, J, Lindemans, C, Turkiewicz, D, Giraldi, E, Nicastro, E, D'Antiga, L, Ackermann, O, Vega, P, Baker A., Remacha E. F., Canizales J. T., Bravo-Gallego L. Y., Fitzpatrick E., Melgar A. A., Bartolo G. M., Guereta L. G., Boluda E. R., Mozo Y., Broniszczak D., Jarmuzek W., Kalicinski P., Maecker-Kolhoff B., Carlens J., Baumann U., Roy C., Chardot C., Benetti E., Cananzi M., Calore E., Dello Strologo L., Candusso M., Lopes M. F., Brito M. J., Goncalves C., Do Carmo C., Stephenne X., Wennberg L., Stone R., Rascon J., Lindemans C., Turkiewicz D., Giraldi E., Nicastro E., D'Antiga L., Ackermann O., and Vega P. J.

Abstract

(1) Background: Post-transplant lymphoproliferative disease (PTLD) is a significant complication of solid organ transplantation (SOT). However, there is lack of consensus in PTLD management. Our aim was to establish a present benchmark for comparison between international centers and between various organ transplant systems and modalities; (2) Methods: A cross-sectional questionnaire of relevant PTLD practices in pediatric transplantation was sent to multidisciplinary teams from 17 European center members of ERN TransplantChild to evaluate the centers’ approach strategies for diagnosis and treatment and how current practices impact a cross-sectional series of PTLD cases; (3) Results: A total of 34 SOT programs from 13 European centers participated. The decision to start preemptive treatment and its guidance was based on both EBV viremia monitoring plus additional laboratory methods and clinical assessment (61%). Among treatment modalities the most common initial practice at diagnosis was to reduce the immunosuppression (61%). A total of 126 PTLD cases were reported during the period 2012-2016. According to their histopathological classification, monomorphic lesions were the most frequent (46%). Graft rejection after PTLD remission was 33%. Of the total cases diagnosed with PTLD, 88% survived; (4) Conclusions: There is still no consensus on prevention and treatment of PTLD, which implies the need to generate evidence. This might successively allow the development of clinical guidelines.

Published
2021

5. Measuring characteristic differences between high- and low-performing discharges on the MegaJOuLe Neutron Imaging Radiography (MJOLNIR) DPF

Author

Schmidt, A., primary, Goyon, C., additional, Link, A., additional, Cooper, C., additional, Anaya, E., additional, Anderson, M., additional, Bartolo, G., additional, Campbell, P. C., additional, Chapman, S., additional, Max, D., additional, McMahon, M., additional, Podpaly, Y. A., additional, and Povilus, A., additional

Published
2022
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7. Marine Strategy Framework Directive- Descriptor 2, Non-Indigenous Species

Author

Tsiamis, Konstantinos, Palialexis, Andreas, Connor, David, Antoniadis, Stavros, Bartilotti, Cátia, Bartolo, G. Angela, Berggreen, Ulrik Christian, Boschetti, Simona, Buschbaum, Christian, Canning-Clode, João, Carbonell, Aina, Castriota, Luca, Corbeau, Clemence, Costa, Ana, Cvitković, Ivan, Despalatović, Marija, Dragičević, Branko, Dulčić, Jakov, Fortič, Ana, Francé, Janja, Gittenberger, Arjan, Gizzi, Francesca, Gollasch, Stephan, Gruszka, Piotr, Hegarty, Mary, Hema, Tatjana, Jensen, Kathe, Josephides, Marios, Kabuta, Saa, Kerckhof, Francis, Kovtun-Kante, Anastasiia, Krakau, Manuela, Kraśniewski, Wojciech, Lackschewitz, Dagmar, Lehtiniemi, Maiju, Lieberum, Christian, Linnamägi, Merike, Lipej, Lovrenc, Livi, Silvia, Lundgreen, Kim, Magliozzi, Chiara, Massé, Cécile, Mavrič, Borut, Michailidis, Nikolas, Moncheva, Snejana, Mozetič, Patricija, Naddafi, Rahmat, Ninčević, Gladan Živana, Ojaveer, Henn, Olenin, Sergej, Orlando-Bonaca, Martina, Ouerghi, Atef, Parente, Manuela, Pavlova, Petya, Peterlin, Monika, Pitacco, Valentina, Png- Gonzalez, Lydia, Rousou, Maria, Sala-Pérez, Manuel, Serrano, Alberto, Skorupski, Jakub, Smolders, Sander, Srebaliene, Greta, Stæhr, Peter Anton, Stefanova, Kremena, Strake, Solvita, Tabarcea, Cristina, Todorova, Valentina, Trkov, Domen, Tuaty-Guerra, Miriam, Vidjak, Olja, Zenetos, Argyro, Žuljević, Ante, and Cardoso, Ana Cristina

Subjects
biodiversity, ecosystem, environmental impact, environmental protection, marine ecosystem, marine life, protection of animal life, report
Published
2021

8. Impact of genotype, serum bile acids, and surgical biliary diversion on native liver survival in FIC1 deficiency

Author

Arıkan, Çiğdem (ORCID 0000-0002-0794-2741 & YÖK ID 240198), van Wessel, D. B. E.; Thompson, R. J.; Gonzales, E.; Jankowska, I.; Shneider, B. L.; Sokal, E.; Grammatikopoulos, T.; Kadaristiana, A.; Jacquemin, E.; Spraul, A.; Lipiński, P.; Czubkowski, P.; Rock, N.; Shagrani, M.; Broering, D.; Algoufi, T.; Mazhar, N.; Nicastro, E.; Kelly, D.; Nebbia, G.; Arnell, H.; Fischler, B.; Hulscher, J. B. F.; Serranti, D.; Debray, D.; Lacaille, F.; Goncalves, C.; Hierro, L.; Muñoz Bartolo, G.; Mozer-Glassberg, Y.; Azaz, A.; Brecelj, J.; Dezsőfi, A.; Luigi Calvo, P.; Krebs-Schmitt, D.; Hartleif, S.; van der Woerd, W. L.; Wang, J. S.; Li, L. T.; Durmaz, Ö.; Kerkar, N.; Hørby Jørgensen, M.; Fischer, R.; Jimenez-Rivera, C.; Alam, S.; Cananzi, M.; Laverdure, N.; Ferreira, C. T.; Ordonez, F.; Wang, H.; Sency, V.; Kim, K. M.; Chen, H. L.; Carvalho, E.; Fabre, A.; Quintero Bernabeu, J.; Alonso, E. M.; Sokol, R. J.; Suchy, F. J.; Loomes, K. M.; McKiernan, P. J.; Rosenthal, P.; Turmelle, Y.; Rao, G. S.; Horslen, S.; Kamath, B. M.; Rogalidou, M.; Karnsakul, W. W.; Hansen, B.; Verkade, H. J., Arıkan, Çiğdem (ORCID 0000-0002-0794-2741 & YÖK ID 240198), and van Wessel, D. B. E.; Thompson, R. J.; Gonzales, E.; Jankowska, I.; Shneider, B. L.; Sokal, E.; Grammatikopoulos, T.; Kadaristiana, A.; Jacquemin, E.; Spraul, A.; Lipiński, P.; Czubkowski, P.; Rock, N.; Shagrani, M.; Broering, D.; Algoufi, T.; Mazhar, N.; Nicastro, E.; Kelly, D.; Nebbia, G.; Arnell, H.; Fischler, B.; Hulscher, J. B. F.; Serranti, D.; Debray, D.; Lacaille, F.; Goncalves, C.; Hierro, L.; Muñoz Bartolo, G.; Mozer-Glassberg, Y.; Azaz, A.; Brecelj, J.; Dezsőfi, A.; Luigi Calvo, P.; Krebs-Schmitt, D.; Hartleif, S.; van der Woerd, W. L.; Wang, J. S.; Li, L. T.; Durmaz, Ö.; Kerkar, N.; Hørby Jørgensen, M.; Fischer, R.; Jimenez-Rivera, C.; Alam, S.; Cananzi, M.; Laverdure, N.; Ferreira, C. T.; Ordonez, F.; Wang, H.; Sency, V.; Kim, K. M.; Chen, H. L.; Carvalho, E.; Fabre, A.; Quintero Bernabeu, J.; Alonso, E. M.; Sokol, R. J.; Suchy, F. J.; Loomes, K. M.; McKiernan, P. J.; Rosenthal, P.; Turmelle, Y.; Rao, G. S.; Horslen, S.; Kamath, B. M.; Rogalidou, M.; Karnsakul, W. W.; Hansen, B.; Verkade, H. J.

Abstract

Mutations in ATP8B1 can lead to familial intrahepatic cholestasis type 1 (FIC1) deficiency, or progressive familial intrahepatic cholestasis type 1 (PFIC1). The rarity of FIC1 deficiency has largely prevented a detailed analysis of its natural history, effects of predicted protein truncating mutations (PPTMs), and possible associations of serum bile acid (sBA) concentrations and surgical biliary diversion (SBD) with long-term outcome. We aimed to provide novel insights by using the largest genetically defined cohort of FIC1 deficiency patients to date. This multicenter, combined retrospective and prospective study included 130 patients with compound heterozygous or homozygous predicted pathogenic ATP8B1 variants. Patients were categorized according to the number of PPTMs (i.e., splice site, frameshift due to deletion or insertion, nonsense, duplication); FIC1-A (n=67; no PPTM), FIC1-B (n=29; one PPTM) or FIC1-C (n=34; two PPTMs). Survival analysis showed an overall native liver survival (NLS) of 44% at age 18y. NLS was comparable between FIC1-A, FIC1-B, and FIC1-C (%NLS at age 10y: 67%, 41%, and 59%, respectively; P=0.12), despite FIC1-C undergoing SBD less often (%SBD at age 10y: 65%, 57%, and 45%, respectively; P=0.03). sBAs at presentation were negatively associated with NLS (NLS at age 10y; sBAs <194 µmol/L: 49% versus sBAs ≥194 µmol/L: 15%; P=0.03). SBD decreased sBAs (230 [125-282] to 74 [11-177] μmol/L; P=0.005). SBD (HR 0.55, 95% CI 0.28-1.03, P=0.06) and post-SBD sBA concentrations <65μmol/L (P=0.05) tended to be associated with improved NLS. Conclusion: Less than half of FIC1 deficiency patients reach adulthood with native liver. The number of PPTMs did not associate with the natural history or prognosis of FIC1 deficiency. sBA concentrations at initial presentation and after SBD provide limited prognostic information on long-term NLS.

Published
2021

11. Simulation-Guided Experiments on the Megajoule Neutron Imaging Radiography (Mjolnir) DPF

Author

Schmidt, A., primary, Anaya, E., additional, Anderson, M., additional, Angus, J., additional, Bartolo, G., additional, Chapman, S., additional, Cooper, C., additional, Drury, O., additional, Goyon, C., additional, Higginson, D., additional, Holod, I., additional, Link, A., additional, McMahon, M., additional, Podpaly, Y., additional, Povilus, A., additional, Durand, A., additional, and Max, D., additional

Published
2020
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15. The ITER toroidal field model coil (TFMC)

Author

Salpietro, E, Maix, R, Bevilacqua, G, Di Bartolo, G, Fillunger, H, Mitchell, N, Turck, B, Libeyre, P, Ulbricht, A, Spadoni, M, Della Corte, A, Bieder, H, Bresson, D, Krischel, D, and Tardivelli, G.E

Published
1999
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17. Designing and manufacturing of the coil support structure of W7-X

Author

Chauvin, D., Koppe, T., Cardella, A., Missal, B., Pilopp, D., Reich, J., Di Bartolo, G., Camin, R., Gonzales, I., Giordano, L., Langone, S., W7-X Team, and W7-X Team

Subjects
Tokamak, Electromagnet, Computer science, Continuous operation, Mechanical Engineering, Mechanical engineering, Superconducting magnet, Fusion power, law.invention, Nuclear Energy and Engineering, law, Electromagnetic coil, Electrical equipment, General Materials Science, Stellarator, Civil and Structural Engineering
Abstract

Wendelstein 7-X (W7-X) is a fully optimized low-shear stellarator and shall demonstrate the reactor potential of this fusion plant. It is presently under construction at the Greifswald Branch Institute of IPP. The superconducting magnet system will allow continuous operation, limited only by the plasma exhaust system whose capacity is designed for 30 min full power operation. The Wendelstein 7-X (W7-X) coils and structures are part of the largest superconducting fusion device being constructed at present. They represent a technical challenge at industrial level and the need for proven techniques and manufacturing processes in accordance to the highest quality standards. The production of these components requires a management of monitoring for quality and tests. The coil system consists of 20 planar and 50 non-planar coils. They are supported by a pentagonal 10 m diameter, 2.5 m high coil support structure (CSS). The CSS is divided into five modules. Each module consists of two equal half modules. The manufacturing status of the CSS and the main project management and technical challenges will be presented. The lessons learned in the large scale production of this difficult kind of support structure will be presented as relevant experience for the realization of similar systems for future fusion devices, such as ITER.

Published
2009

18. Bibliografia Ogliastrina

Author

Bartolo G., Brandas G. F., DE WAELE, JO HILAIRE AGNES, Bartolo G., Brandas G.F., and De Waele J.

Subjects
OGLIASTRA, BIBLIOGRAFIA, SARDEGNA
Abstract

Bibliografia su tutti gli scritti (libri, articoli scientifici, articoli su giornali, tesi di laurea ecc.) che trattano la regione geografica dell'Ogliastra, con 5764 titoli inseriti e suddivisi per argomenti, e 563 tesi di laurea. L'opera è il risultato di oltre 10 anni di ricerche bibliografiche.

Published
2012

19. Study on UF PES Membranes Spray-Coated with Polymerizable Bicontinuous Microemulsion Materials for Low-Fouling Behavior

Author

Sneha De, Jonathan Heer, Suwetha Sankar, Fabian Geiger, Ephraim Gukelberger, Francesco Galiano, Raffaella Mancuso, Bartolo Gabriele, Alberto Figoli, and Jan Hoinkis

Subjects
membrane fouling, fouling propensity, low-fouling layer, PBM-coated membranes, spray coating, critical flux, Chemical technology, TP1-1185, Chemical engineering, TP155-156
Abstract

The low-fouling propensity of commercially available polyethersulfone (PES) membranes was studied after modification of the membrane surface via coating with polymerizable bicontinuous microemulsion (PBM) materials. The PBM coating was polymerized within 1 min using ultraviolet (UV) light exposure. It was detected on the PES membrane surface via attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. The PBM coating led to an average 10% increase in the hydrophilicity of the PES membrane surface and an increase in total organic content (TOC) removal by more than 15%. Flux-step tests were conducted with model foulant comprising 100 mg L−1 humic acid (HA) solution to detect the onset of critical fouling, characterized by a rapid and substantial increase in TMP, and to compare the fouling propensity of commercially available PES membranes with PBM-coated membranes. The critical flux was found to be about 40% higher for PBM spray-coated membrane and 20% lower for PBM casting-coated membrane than the commercial PES membrane. This demonstrates the performance advantages of the thin PBM layer spray-coated on PES membrane compared to the thick casting-coated PBM layer. The study showcases the potential of PBM spray-coated membranes over commercial PES membranes for use in membrane bioreactors (MBR) for wastewater treatment systems with reduced maintenance over longer operation periods.

Published
2023
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20. Palladium Iodide Catalyzed Multicomponent Carbonylative Synthesis of 2-(4-Acylfuran-2-yl)acetamides

Author

Ida Ziccarelli, Lucia Veltri, Tommaso Prestia, Roberta Amuso, Maria A. Chiacchio, Raffaella Mancuso, and Bartolo Gabriele

Subjects
alkynes, amides, aminocarbonylation, carbonylation, C–H activation, conjugate addition, Organic chemistry, QD241-441
Abstract

2-Propargyl-1,3-dicarbonyl compounds have been carbonylated under oxidative conditions and with the catalysis of the PdI2/KI catalytic system to selectively afford previously unreported 2-(4-acylfuran-2-yl)acetamides in fair to good yields (54–81%) over 19 examples. The process takes place under relatively mild conditions and occurs via a mechanistic pathway involving Csp-H activation by oxidative monoamincarbonylation of the terminal triple bond of the substrates with formation of 2-ynamide intermediates, followed by 5-exo-dig O-cyclization (via intramolecular conjugate addition of the in situ formed enolate to the 2-ynamide moiety) and aromative isomerization.

Published
2023
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21. La bibliografia speleologica della Sardegna (1580-2006)

Author

Bartolo G., Grafitti G., Mucedda M., Villani M., DE WAELE, JO HILAIRE AGNES, Bartolo G., De Waele J., Grafitti G., Mucedda M., and Villani M.

Subjects
GROTTE, BIBLIOGRAFIA, BANCA DATI, SARDEGNA, SPELEOLOGIA
Abstract

Scopo del presente lavoro, primo del genere per la Sardegna, è quello di mettere a disposizione non solo degli speleologi, ma anche di tutti coloro che intendono o intenderanno occuparsi delle grotte naturali e artificiali della nostra Isola, quanto è stato scritto sull’argomento. Si è trattato di una lunga ricerca, durata oltre sei anni, nel corso dei quali abbiamo selezionato e catalogato opere monografiche, articoli e saggi, consultando libri, bollettini, riviste e quotidiani alla ricerca non solo di lavori d’interesse prettamente speleologico, ma anche archeologico, biologico, naturalistico, geografico, geologico, paleontologico etc. Tutte le pubblicazioni reperite, in cui si descrivono o si citano grotte sarde, sono state catalogate in una banca dati Access, nella quale sono state raccolte informazioni sui tipi d’argomenti trattati (archeologia, geologia, biospeleologia etc.). Questo ha consentito di fare complesse interrogazioni al database con combinazioni d’informazioni geografiche di ciascuna grotta (numero catastale, comune, nome), con gli argomenti trattati negli articoli catalogati. Chiaramente il libro, di prossima pubblicazione, non è certo destinato a un grosso pubblico, ma ad una stretta cerchia di persone che, per passione (speleologi, escursionisti) o per lavoro (archeologi, geologi, biologi, etc.), sono e saranno interessate ad avere un’ampia guida bibliografica a supporto delle loro attività e ricerche.

Published
2008

22. L'Ogliastra. Vicende Ambiente Tradizioni Grotte

Author

Bartolo G., DE WAELE, JO HILAIRE AGNES, Bartolo G., and De Waele J.

Subjects
AMBIENTE, OGLIASTRA, STORIA, SPELEOLOGIA
Abstract

Volume contenente cenni storici e descrizioni culturali e naturalistiche del territorio della nuova provincia d'Ogliastra, ampiamente documentata attraverso numersoe immagini. Nella parte naturalistica si descrive il territorio, la geologia, la fauna e la flora, l'archeologia, oltre a dare informazioni sulla tutela ambientale e sulla valorizzazione. Il volume contiene una descrizione dettagliata dei 23 paesi che compongono la provincia. Il volume chiude con un capitolo sulla Speleologia corredata dai rilievi topografici delle maggiori grotte.

Published
2007

27. An Overview of Catalytic Carbonylative Double Cyclization Reactions

Author

Bartolo Gabriele, Raffaella Mancuso, Nicola Della Ca’, Lucia Veltri, and Ida Ziccarelli

Subjects
carbonylation, cyclization, double cyclization, fused heterocycles, heterocyclization, heterocycles, Chemical technology, TP1-1185, Chemistry, QD1-999
Abstract

This short review is aimed at giving an overview of catalytic carbonylative double cyclization reactions, which are processes in which suitable organic substrates and carbon monoxide are sequentially activated by a promoting a catalyst to form two new cycles with the concomitant incorporation of carbon monoxide as a carbonyl function in the final product. Paradigmatic examples of this powerful synthetic methodology, which allows the one-step synthesis of complex molecular architectures from simple building blocks using the simplest and readily available C-1 unit (CO), are illustrated and discussed. The review is divided into five sections: (1) Introduction, (2) Functionalized Olefinic Substrates, (3) Functionalized Acetylenic Substrates, (4) Functionalized Halides, (5) Conclusions and Future Perspectives.

Published
2023
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29. Le Orchidaceae swi Monti Erei (Sicilia centrale)

Author

Bartolo, G., Ganci, S., and Pulvirenti, Santa Gloria

Subjects
Orchidaceae, distribution, cartography UTM, Erei Mounts, C - Sicily, C - Sicily, distribution, cartography UTM, Erei Mounts, Orchidaceae
Published
2011

30. Managment of patients with latex allergy: latex free-protocols

Author

Azzolina, R, LA CAMERA, Giuseppa, Messina, A, Navarria, D. V., Chiarenza, F, Cavaleri, M, Fiorino, S. L., Celestri, M, Di Francesco, A, and Di bartolo, G. L.

Subjects
sensibilizzazione, manifestazioni, IgE mediation reaction, sensitization, clinical, Reazione IgE mediata, sensibilizzazione, manifestazioni, Reazione IgE mediata, IgE mediation reaction, sensitization, clinical
Published
2011

31. Anaphylactic shock from the bite of vipera Aspis hugy

Author

Azzolina, R., Giuseppa LA CAMERA, Messina, A., Di Francesco, A., Chiarenza, F., Cavaleri, M., Navarria, D. V., Fiorino, L. S., Celestri, M., and Di Bartolo, G. L.

Subjects
Viperidi, spreading poison, serum antivenom, Viperidi, diffusione del veleno, siero antiveleno, spreading poison, siero antiveleno, Viperidi, serum antivenom, diffusione del veleno
Published
2011

33. L’Orto Siculo dell’Università di Catania.Da Tornabene a oggi: progetto scientifico e realizzazioni concrete. The Sicilian Garden of Catania University.From Tornabene to the present day: a scientific project and its concrete realisations

Author

Bartolo, G., Brullo, C., and Pulvirenti, Santa Gloria

Subjects
Catania, Orto Botanico, Orto Siculo, storia scientifica, Catania, Botanical Garden, Sicilian Garden, scientific history, Orto Botanico, Orto Siculo, Catania, storia scientifica, scientific history, Botanical Garden, Sicilian Garden
Published
2010

35. Storia scientifica e assetto attuale dell’Orto siculo dell’Università di Catania

Author

Bartolo, G, Brullo, C, and Pulvirenti, Santa Gloria

Subjects
Orto botanico, Orto siculo, Elenco floristico, Storia locale, Catania, Botanical Garden, Sicilian garden, Floristic checklist, Local history, Catania, Storia locale, Sicilian garden, Local history, Elenco floristico, Catania, Orto botanico, Orto siculo, Botanical Garden, Floristic checklist
Published
2010

47. Karyomorphology, heterochromatin patterns and evolution in the genus Ophrys (Orchidaceae)

Author

D’Emerico S., Pignone D., Bartolo G., Pulvirenti S., Terrasi C., Stuto S., and Scrugli A.

Abstract

Karyomorphology and relationships between three genera within Orchidinae (Orchidaceae). In the present contribution, karyomorphology, cytological heterochromatin amounts, and chromosomal C-bands distribution, are used as landmarks to study relationships among three genera of the family Orchidaceae, namely, Anacamptis, Ophrys and Serapias. The obtained data suggest a possible pathway of karyotype evolution in which the genus Anacamptis is the one from which both Ophrys and Serapias evolved; the differences in karyomorphology and, possibly, evolutionary rates are discussed in terms of species adaptation.

Published
2005

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