776 results on '"Bartels D"'
Search Results
2. The Orai1 Antagonist ELD607 Safely Reduces Lung Inflammation in G551D Cystic Fibrosis Ferrets
- Author
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Sassano, F., primary, Ahmad, S., additional, Iskarpatyoti, J., additional, Schmalstig, A., additional, Glawe, D., additional, Fakhari, S., additional, Engelhardt, J.F., additional, Bartels, D., additional, and Tarran, R., additional
- Published
- 2024
- Full Text
- View/download PDF
3. PlantACT! - how to tackle the climate crisis
- Author
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King Abdullah University of Science and Technology, European Commission, Hirt, Heribert [0000-0003-3119-9633], Al-Babili, Salim [0000-0003-4823-2882], Almeida-Trapp, Marilia [0000-0002-9980-322X], Aranda, Manuel [0000-0001-6673-016X], Bartels, D. [0000-0003-0505-3083], Bennett, Malcom [0000-0003-0475-390X], Blilou, Ikram [0000-0001-8003-3782], Boer, Damian [0000-0003-1240-2253], Boulouis, Alix [0000-0002-2552-3938], Bowler, Chris [0000-0003-3835-6187], Brunel-Muguet, Sophie [0000-0001-6940-4618], Chardon, Fabien [0000-0001-7909-3884], Colcombet, Jean [0000-0002-0176-3857], Colot, Vincent [0000-0002-6382-1610], Daszkowska-Golec, Agata [0000-0001-9479-0813], Dinneny, Jose R. [0000-0002-3998-724X], Field, Ben [0000-0003-2142-4606], Gardener, Catherine H. [0000-0001-8528-3772], Gojon, Alain [0000-0001-5412-8606], Gomès, Eric [0000-0003-2582-1203], Gomez-Alvarez, Eva María [0000-0002-1284-7212], Gutiérrez Armenta, Crisanto [0000-0001-8905-8222], Havaux, Michel [0000-0002-6434-393X], Hayes, Scott [0000-0001-8943-6238], Heard, Edith [0000-0001-8052-7117], Alghamdi, Amal Khalaf [0000-0002-3491-5271], Laplaze, Laurent [0000-0002-6568-6504], Lauersen, Kyle J. [0000-0002-5538-7201], Leonhardt, Nathalie [0000-0002-5392-9732], Johnson, Xenie [0000-0003-3424-7047], Jones, Jonathan [0000-0002-4953-261X], Kollist, Hannes [0000-0002-6895-3583], Kopriva, Stanislav [0000-0002-7416-6551], Krapp, Anne [0000-0003-2034-5615], Masson, Mauricio Lopez-Portillo [0000-0003-3895-6254], McCabe, Matthew F. [0000-0002-1279-5272], Merendino, Livia [0000-0003-1593-5442], Molina, Antonio [0000-0003-3137-7938], Moreno Ramirez, Jose L. [0000-0002-0907-1361], Mueller-Roeber, Bernd [0000-0002-1410-464X], Nicolas, Michael [0000-0002-7311-5306], Nir, Ido [0000-0002-6223-6700], Pardo, José M. [0000-0003-4510-8624], Reichheld, Jean-Philippe [0000-0001-6884-0602], Rodriguez, Pedro [0000-0002-5886-9425], Rouached, Hatem [0000-0002-7751-0477], Saad, Maged M. [0000-0002-5655-8674], Schlögelhofer, Peter [0000-0002-0909-3587], De Smet, Ive [0000-0003-4607-8893], Stanschewski, Clara [0000-0002-3596-9108], Stra, Alice [0000-0002-0856-6039], Tester, Mark [0000-0002-5085-8801], Weber, A. [0000-0003-0970-4672], Weigel, Detlef [0000-0002-2114-7963], Wigge, Philip [0000-0003-4822-361X], Wrzaczek, Michael [0000-0002-5946-9060], Wulff, Brande B.H. [0000-0003-4044-4346], Hirt, Heribert, Al-Babili, Salim, Almeida-Trapp, Marilia, Martin, Antoine, Aranda, Manuel, Bartels, D., Bennett, Malcom, Blilou, Ikram, Boer, Damian, Boulouis, Alix, Bowler, Chris, Brunel-Muguet, Sophie, Chardon, Fabien, Colcombet, Jean, Colot, Vincent, Daszkowska-Golec, Agata, Dinneny, Jose R., Field, Ben, Froehlich, Katja, Gardener, Catherine H., Gojon, Alain, Gomès, Eric, Gomez-Alvarez, Eva María, Gutiérrez Armenta, Crisanto, Havaux, Michel, Hayes, Scott, Heard, Edith, Hodges, Michael, Alghamdi, Amal Khalaf, Laplaze, Laurent, Lauersen, Kyle J., Leonhardt, Nathalie, Johnson, Xenie, Jones, Jonathan, Kollist, Hannes, Kopriva, Stanislav, Krapp, Anne, Masson, Mauricio Lopez-Portillo, McCabe, Matthew F., Merendino, Livia, Molina, Antonio, Moreno Ramirez, Jose L., Mueller-Roeber, Bernd, Nicolas, Michael, Nir, Ido, Orduna, Izamar Olivas, Pardo, José M., Reichheld, Jean-Philippe, Rodriguez, Pedro, Rouached, Hatem, Saad, Maged M., Schlögelhofer, Peter, Singh, Kirti A., De Smet, Ive, Stanschewski, Clara, Stra, Alice, Tester, Mark, Walsh, Catherine, Weber, A., Weigel, Detlef, Wigge, Philip, Wrzaczek, Michael, Wulff, Brande B.H., Young, Iain M., King Abdullah University of Science and Technology, European Commission, Hirt, Heribert [0000-0003-3119-9633], Al-Babili, Salim [0000-0003-4823-2882], Almeida-Trapp, Marilia [0000-0002-9980-322X], Aranda, Manuel [0000-0001-6673-016X], Bartels, D. [0000-0003-0505-3083], Bennett, Malcom [0000-0003-0475-390X], Blilou, Ikram [0000-0001-8003-3782], Boer, Damian [0000-0003-1240-2253], Boulouis, Alix [0000-0002-2552-3938], Bowler, Chris [0000-0003-3835-6187], Brunel-Muguet, Sophie [0000-0001-6940-4618], Chardon, Fabien [0000-0001-7909-3884], Colcombet, Jean [0000-0002-0176-3857], Colot, Vincent [0000-0002-6382-1610], Daszkowska-Golec, Agata [0000-0001-9479-0813], Dinneny, Jose R. [0000-0002-3998-724X], Field, Ben [0000-0003-2142-4606], Gardener, Catherine H. [0000-0001-8528-3772], Gojon, Alain [0000-0001-5412-8606], Gomès, Eric [0000-0003-2582-1203], Gomez-Alvarez, Eva María [0000-0002-1284-7212], Gutiérrez Armenta, Crisanto [0000-0001-8905-8222], Havaux, Michel [0000-0002-6434-393X], Hayes, Scott [0000-0001-8943-6238], Heard, Edith [0000-0001-8052-7117], Alghamdi, Amal Khalaf [0000-0002-3491-5271], Laplaze, Laurent [0000-0002-6568-6504], Lauersen, Kyle J. [0000-0002-5538-7201], Leonhardt, Nathalie [0000-0002-5392-9732], Johnson, Xenie [0000-0003-3424-7047], Jones, Jonathan [0000-0002-4953-261X], Kollist, Hannes [0000-0002-6895-3583], Kopriva, Stanislav [0000-0002-7416-6551], Krapp, Anne [0000-0003-2034-5615], Masson, Mauricio Lopez-Portillo [0000-0003-3895-6254], McCabe, Matthew F. [0000-0002-1279-5272], Merendino, Livia [0000-0003-1593-5442], Molina, Antonio [0000-0003-3137-7938], Moreno Ramirez, Jose L. [0000-0002-0907-1361], Mueller-Roeber, Bernd [0000-0002-1410-464X], Nicolas, Michael [0000-0002-7311-5306], Nir, Ido [0000-0002-6223-6700], Pardo, José M. [0000-0003-4510-8624], Reichheld, Jean-Philippe [0000-0001-6884-0602], Rodriguez, Pedro [0000-0002-5886-9425], Rouached, Hatem [0000-0002-7751-0477], Saad, Maged M. [0000-0002-5655-8674], Schlögelhofer, Peter [0000-0002-0909-3587], De Smet, Ive [0000-0003-4607-8893], Stanschewski, Clara [0000-0002-3596-9108], Stra, Alice [0000-0002-0856-6039], Tester, Mark [0000-0002-5085-8801], Weber, A. [0000-0003-0970-4672], Weigel, Detlef [0000-0002-2114-7963], Wigge, Philip [0000-0003-4822-361X], Wrzaczek, Michael [0000-0002-5946-9060], Wulff, Brande B.H. [0000-0003-4044-4346], Hirt, Heribert, Al-Babili, Salim, Almeida-Trapp, Marilia, Martin, Antoine, Aranda, Manuel, Bartels, D., Bennett, Malcom, Blilou, Ikram, Boer, Damian, Boulouis, Alix, Bowler, Chris, Brunel-Muguet, Sophie, Chardon, Fabien, Colcombet, Jean, Colot, Vincent, Daszkowska-Golec, Agata, Dinneny, Jose R., Field, Ben, Froehlich, Katja, Gardener, Catherine H., Gojon, Alain, Gomès, Eric, Gomez-Alvarez, Eva María, Gutiérrez Armenta, Crisanto, Havaux, Michel, Hayes, Scott, Heard, Edith, Hodges, Michael, Alghamdi, Amal Khalaf, Laplaze, Laurent, Lauersen, Kyle J., Leonhardt, Nathalie, Johnson, Xenie, Jones, Jonathan, Kollist, Hannes, Kopriva, Stanislav, Krapp, Anne, Masson, Mauricio Lopez-Portillo, McCabe, Matthew F., Merendino, Livia, Molina, Antonio, Moreno Ramirez, Jose L., Mueller-Roeber, Bernd, Nicolas, Michael, Nir, Ido, Orduna, Izamar Olivas, Pardo, José M., Reichheld, Jean-Philippe, Rodriguez, Pedro, Rouached, Hatem, Saad, Maged M., Schlögelhofer, Peter, Singh, Kirti A., De Smet, Ive, Stanschewski, Clara, Stra, Alice, Tester, Mark, Walsh, Catherine, Weber, A., Weigel, Detlef, Wigge, Philip, Wrzaczek, Michael, Wulff, Brande B.H., and Young, Iain M.
- Abstract
Greenhouse gas (GHG) emissions have created a global climate crisis which requires immediate interventions to mitigate the negative effects on all aspects of life on this planet. As current agriculture and land use contributes up to 25% of total GHG emissions, plant scientists take center stage in finding possible solutions for a transition to sustainable agriculture and land use. In this article, the PlantACT! (Plants for climate ACTion!) initiative of plant scientists lays out a road map of how and in which areas plant scientists can contribute to finding immediate, mid-term, and long-term solutions, and what changes are necessary to implement these solutions at the personal, institutional, and funding levels.
- Published
- 2023
4. Huanglongbing in Texas: Report on the first detections in commercial citrus
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da Graça, J. V., Kunta, M., Sétamou, M., Rascoe, J., Li, W., Nakhla, M. K., Salas, B., and Bartels, D. W.
- Abstract
Huanglongbing (HLB), also known as citrus greening, is a destructive citrus disease associated with 3 α-proteobacteria species of Candidatus Liberibacter. The first report of HLB in the USA was from Florida in 2005 and Ca. L. asiaticus (Las) is the only species currently confirmed in the USA. In January 2012, a Valencia sweet orange tree in a commercial orchard in San Juan, Texas, tested positive for Las by real-time and conventional PCR assays and by the sequence of its partial 16S rRNA gene. The sample tested negative for Ca. L. americanus and Ca. L. africanus. All 4 Valencia sweet orange seedlings that were graft-inoculated using budwood from the first Texas HLB-infected tree showed typical HLB symptoms 3 months post-inoculation and tested positive for the pathogen. Such HLB typical symptoms as leaf blotchy mottle, twig die-back, veinal chlorosis, lopsided and greening fruits were observed on the Las-positive tree in the orchard, which immediately triggered an intensive survey of the disease in the area. Typical HLB symptoms were found on 54 Valencia sweet orange trees in the same orchard and 18 Rio Red grapefruit trees in an adjacent orchard. All these symptomatic trees tested positive for Las by PCR and sequencing.
- Published
- 2015
5. 163 Ferret pulmonary ionocytes abundance is regulated by extracellular osmolarity in air-liquid interface culture
- Author
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Gasser, G., primary, Yuan, F., additional, Zhang, Y., additional, Heil, M., additional, Yi, Y., additional, Yan, Z., additional, Bartels, D., additional, Liu, X., additional, Sun, X., additional, and Engelhardt, J., additional
- Published
- 2023
- Full Text
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6. 363 Role of diet in pregnancy associated morbidity in cystic fibrosis ferrets
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Yi, Y., primary, Corrigan, E., additional, Nugent, E., additional, Lacina, A., additional, Harvison, J., additional, Yang, Q., additional, Liang, B., additional, Snow, G., additional, Xie, Y., additional, Li, W., additional, Robertson, C., additional, Liu, G., additional, Sun, X., additional, Engelhardt, J., additional, and Bartels, D., additional
- Published
- 2023
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7. 225 Anatomical organization of salivary gland ionocytes in the ferret mapped by FOXI1 lineage tracing
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Sun, X., primary, Yuan, F., additional, Wu, P., additional, Liang, B., additional, Liu, G., additional, Weng, Y., additional, Bartels, D., additional, and Engelhardt, J., additional
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- 2023
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8. 160 LUNAR-CFTR mRNA improves mucociliary clearance in cystic fibrosis ferrets
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Liu, X., primary, Luo, M., additional, Snow, G., additional, Fakhari, S., additional, Pei, Y., additional, Wu, S., additional, Ma, J., additional, Bartels, D., additional, Shukla, S., additional, Boehme, S., additional, Geller, D., additional, and Engelhardt, J., additional
- Published
- 2023
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9. 169 MUC5B and MUC5AC are both required for effective airway mucociliary clearance in ferrets
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Zhang, Y., primary, Evans, I., additional, Yuan, F., additional, Ievlev, V., additional, Moninger, T., additional, Ermund, A., additional, He, N., additional, Guo, L., additional, Yi, Y., additional, Sun, X., additional, Hansson, G., additional, Bartels, D., additional, and Engelhardt, J., additional
- Published
- 2023
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10. 44 Characterization of Pseudomonas aeruginosa lung colonization in adolescent cystic fibrosis ferrets
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Lacina, A., primary, Corrigan, E., additional, Fakhari, S., additional, Nugent, E., additional, Shonka, A., additional, Snow, G., additional, Sun, X., additional, Engelhardt, J., additional, and Bartels, D., additional
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- 2023
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11. 162 A common FOXI1-lineage progenitor specifies pulmonary ionocytes, pulmonary neuroendocrine cells, and tuft cells
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Yuan, F., primary, Lemire, E., additional, Gasser, G., additional, Montoro, D., additional, Jagadeesh, K., additional, Zhang, Y., additional, Duan, Y., additional, Heil, M., additional, Yi, Y., additional, Bartels, D., additional, Liu, X., additional, Yan, Z., additional, Sun, X., additional, Haber, A., additional, and Engelhardt, J., additional
- Published
- 2023
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12. Placebo- und Noceboeffekte bei Pruritus: Methodologische und klinische Implikationen
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Tekampe, J., Peerdeman, K. J., Bartels, D. J. P., van Laarhoven, A. I. M., and Evers, A. W. M.
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- 2018
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13. Phytosanitary Treatments
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Hennessey, M. K., Jeffers, L., Nendick, D., Glassy, Ken, Floyd, L., Hansen, J. D., Bailey, W. D., Winborne, I., Bartels, D., Ramsey, C., Devorshak, C., Gordh, Gordon, editor, and McKirdy, Simon, editor
- Published
- 2014
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14. 425 Development of an AICDA-CreERT2 ferret model to study adaptive humoral immunity
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Lynch, T., primary, Sun, X., additional, Tang, Y., additional, Bartels, D., additional, Gries, C., additional, Liang, B., additional, Ievlev, V., additional, Bishop, G., additional, Parekh, K., additional, and Engelhardt, J., additional
- Published
- 2022
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15. 258 Impact of temporal changes in cystic fibrosis transmembrane conductance regulator activity on fertility, conception, pregnancy, and lactation in ferrets with cystic fibrosis
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Sun, X., primary, Yi, Y., additional, Liang, B., additional, Wu, P., additional, Liu, G., additional, Bartels, D., additional, and Engelhardt, J., additional
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- 2022
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16. 602 Optimization of cystic fibrosis transmembrane conductance regulatorG551D ferret model for early synchronized lung microbial colonization
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Lacina, A., primary, Shonka, A., additional, Zhang, Y., additional, Edwin, I., additional, Nugent, E., additional, Apak, I., additional, Corrigan, E., additional, Sun, X., additional, Limoli, D., additional, Engelhardt, J., additional, and Bartels, D., additional
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- 2022
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17. 665 Single-cell ribonucleic acid sequencing reveals pulmonary ionocytes subtypes in proximal ferret airway epithelium
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Yuan, F., primary, Gasser, G., additional, Montoro, D., additional, Jagadeesh, K., additional, Lemire, E., additional, Liu, X., additional, Sun, X., additional, Bartels, D., additional, Haber, A., additional, and Engelhardt, J., additional
- Published
- 2022
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18. Learning by Building (Destroying and Tinkering, Too): A Powerful Science Communication Tool
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Altmann, V., Tamez, M., Bartels, D., Tobin, Ken, editor, Stocklmayer, Susan M., editor, Gore, Michael M., editor, and Bryant, Chris, editor
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- 2001
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19. Genetic Transformation of Craterostigma plantagineum
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Furini, A., Salamini, F., Bartels, D., and Bajaj, Y. P. S., editor
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- 2001
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20. Molecular Analysis of Cold-Hardening in Barley
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Cattivelli, L., Crosatti, C., Grossi, M., Portesi, A., Rizza, F., Stanca, A. M., Furini, A., Bartels, D., and Cherry, Joe H., editor
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- 1994
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21. Transparency and Reproducibility of Observational Cohort Studies Using Large Healthcare Databases.
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Wang, S V, Verpillat, P, Rassen, J A, Patrick, A, Garry, E M, and Bartels, D B
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- 2016
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22. Expression of luciferase in transgenic tobacco mediated by a promoter element from desiccation tolerant Craterostigma plantagineum
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Dale, P. L., Båga, M., Szalay, A. A., Piatkowski, D., Salamini, F., Bartels, D., Bliss, F. A., editor, Karssen, C. M., editor, van Loon, L. C., editor, and Vreugdenhil, D., editor
- Published
- 1992
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23. Molecular Analysis of Desiccation Tolerance in the Resurrection Plant Craterostigma Plantagineum
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Bartels, D., Schneider, K., Piatkowski, D., Elster, R., Iturriaga, G., Terstappen, G., Binh, Le Tran, Salamini, F., Herrmann, R. G., editor, and Larkins, B. A., editor
- Published
- 1991
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24. Callus from the resurrection plant Craterostigma plantagineum is a versatile tool to study ABA-mediated gene expression
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Bartels, D., Summerfield, R. J., editor, Altman, Arie, editor, Ziv, Meira, editor, and Izhar, Shamay, editor
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- 1999
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25. 613: Impact of VX-770 on fertility, pregnancy, and lactation in second-generation CFTRG551D/G551D ferrets
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Sun, X., primary, Liang, B., additional, Yi, Y., additional, Wang, H., additional, Wu, P., additional, Bartels, D., additional, and Engelhardt, J., additional
- Published
- 2021
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26. 658: In utero CFTR modulator therapy protects from meconium ileus and improves postnatal survival in F508del ferrets
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Evans, T., primary, Liang, B., additional, Yan, Z., additional, Sun, X., additional, Yi, Y., additional, Vegter, A., additional, Guo, L., additional, Yang, Y., additional, Feng, Z., additional, Park, S., additional, Qi, L., additional, Bartels, D., additional, Gibson, K., additional, Meyerholz, D., additional, and Engelhardt, J., additional
- Published
- 2021
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27. 663: LUNAR efficiently delivers mRNA into ferret airway epithelial cells in vitro and in vivo
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Liu, X., primary, Luo, M., additional, Pei, Y., additional, Bao, B., additional, Cai, Q., additional, Liang, B., additional, Bartels, D., additional, Perez-Garcia, C., additional, and Engelhardt, J., additional
- Published
- 2021
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28. 666: Genome editing in ferret airway epithelia mediated by CRISPR/nucleases delivered with amphiphilic peptide shuttles
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Liu, X., primary, Luo, M., additional, Hallée, S., additional, Cai, Q., additional, Liang, B., additional, Bartels, D., additional, Guay, D., additional, and Engelhardt, J., additional
- Published
- 2021
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29. The tail(ed) end of things: a study of suffixation in select mammal and bird names in insular Celtic
- Author
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Bartels, D., Ó Flaithearta, M. (Thesis Advisor), Bartels, D., and Ó Flaithearta, M. (Thesis Advisor)
- Abstract
Suffixation is the most common way of word-formation in Indo-European languages, and one of the several ways in which animal terms, lexical items that refer to specific animals, can be formed. In this thesis the process of suffixation will be examined through a corpus of Irish and Welsh mammal and bird names ending in one of the Irish suffixes -ach, -ech; -óc, -óg; -án or Welsh suffixes -og; -en, -yn. This thesis argues that these suffixes are attached to a base with a morphological and semantic motivation. The Irish suffix -ach, -ech and Welsh suffix -og, -iog are adjectival suffixes in origin, but adjectival derivations based on a noun or adjective can be substantivized and become substantival mammal and bird terms. The Irish suffixes -óc, -óg; -án and Welsh suffix -en, -yn do not have a clear morphological function, but they are employed to form substantival derivatives from adjectival or substantival bases. All suffixes are also connected on a semantic level: all examined suffixes correspond to three semantic categories as proposed by Paul Russell.
- Published
- 2021
30. Phytosanitary Treatments
- Author
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Hennessey, M. K., primary, Jeffers, L., additional, Nendick, D., additional, Glassy, Ken, additional, Floyd, L., additional, Hansen, J. D., additional, Bailey, W. D., additional, Winborne, I., additional, Bartels, D., additional, Ramsey, C., additional, and Devorshak, C., additional
- Published
- 2013
- Full Text
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31. Crowdsourcing hypothesis tests: Making transparent how design choices shape research results
- Author
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Landy, J, Jia, M, Ding, I, Viganola, D, Tierney, W, Dreber, A, Johannesson, M, Pfeiffer, T, Ebersole, C, Gronau, Q, Ly, A, van den Bergh, D, Marsman, M, Derks, K, Wagenmakers, E, Proctor, A, Bartels, D, Bauman, C, Brady, W, Cheung, F, Cimpian, A, Dohle, S, Donnellan, M, Hahn, A, Hall, M, Jiménez-Leal, W, Johnson, D, Lucas, R, Monin, B, Montealegre, A, Mullen, E, Pang, J, Ray, J, Reinero, D, Reynolds, J, Sowden, W, Storage, D, Su, R, Tworek, C, Van Bavel, J, Walco, D, Wills, J, Xu, X, Yam, K, Yang, X, Cunningham, W, Schweinsberg, M, Urwitz, M, The Crowdsourcing Hypothesis Tests, C, Uhlmann, E, Mari, S, Landy, Justin F, Jia, Miaolei Liam, Ding, Isabel L, Viganola, Domenico, Tierney, Warren, Dreber, Anna, Johannesson, Magnus, Pfeiffer, Thomas, Ebersole, Charles R, Gronau, Quentin F, Ly, Alexander, van den Bergh, Don, Marsman, Maarten, Derks, Koen, Wagenmakers, Eric-Jan, Proctor, Andrew, Bartels, Daniel M, Bauman, Christopher W, Brady, William J, Cheung, Felix, Cimpian, Andrei, Dohle, Simone, Donnellan, M Brent, Hahn, Adam, Hall, Michael P, Jiménez-Leal, William, Johnson, David J, Lucas, Richard E, Monin, Benoît, Montealegre, Andres, Mullen, Elizabeth, Pang, Jun, Ray, Jennifer, Reinero, Diego A, Reynolds, Jesse, Sowden, Walter, Storage, Daniel, Su, Runkun, Tworek, Christina M, Van Bavel, Jay J, Walco, Daniel, Wills, Julian, Xu, Xiaobing, Yam, Kai Chi, Yang, Xiaoyu, Cunningham, William A, Schweinsberg, Martin, Urwitz, Molly, The Crowdsourcing Hypothesis Tests Collaboration, Uhlmann, Eric L, Landy, J, Jia, M, Ding, I, Viganola, D, Tierney, W, Dreber, A, Johannesson, M, Pfeiffer, T, Ebersole, C, Gronau, Q, Ly, A, van den Bergh, D, Marsman, M, Derks, K, Wagenmakers, E, Proctor, A, Bartels, D, Bauman, C, Brady, W, Cheung, F, Cimpian, A, Dohle, S, Donnellan, M, Hahn, A, Hall, M, Jiménez-Leal, W, Johnson, D, Lucas, R, Monin, B, Montealegre, A, Mullen, E, Pang, J, Ray, J, Reinero, D, Reynolds, J, Sowden, W, Storage, D, Su, R, Tworek, C, Van Bavel, J, Walco, D, Wills, J, Xu, X, Yam, K, Yang, X, Cunningham, W, Schweinsberg, M, Urwitz, M, The Crowdsourcing Hypothesis Tests, C, Uhlmann, E, Mari, S, Landy, Justin F, Jia, Miaolei Liam, Ding, Isabel L, Viganola, Domenico, Tierney, Warren, Dreber, Anna, Johannesson, Magnus, Pfeiffer, Thomas, Ebersole, Charles R, Gronau, Quentin F, Ly, Alexander, van den Bergh, Don, Marsman, Maarten, Derks, Koen, Wagenmakers, Eric-Jan, Proctor, Andrew, Bartels, Daniel M, Bauman, Christopher W, Brady, William J, Cheung, Felix, Cimpian, Andrei, Dohle, Simone, Donnellan, M Brent, Hahn, Adam, Hall, Michael P, Jiménez-Leal, William, Johnson, David J, Lucas, Richard E, Monin, Benoît, Montealegre, Andres, Mullen, Elizabeth, Pang, Jun, Ray, Jennifer, Reinero, Diego A, Reynolds, Jesse, Sowden, Walter, Storage, Daniel, Su, Runkun, Tworek, Christina M, Van Bavel, Jay J, Walco, Daniel, Wills, Julian, Xu, Xiaobing, Yam, Kai Chi, Yang, Xiaoyu, Cunningham, William A, Schweinsberg, Martin, Urwitz, Molly, The Crowdsourcing Hypothesis Tests Collaboration, and Uhlmann, Eric L
- Abstract
To what extent are research results influenced by subjective decisions that scientists make as they design studies? Fifteen research teams independently designed studies to answer five original research questions related to moral judgments, negotiations, and implicit cognition. Participants from 2 separate large samples (total N > 15,000) were then randomly assigned to complete 1 version of each study. Effect sizes varied dramatically across different sets of materials designed to test the same hypothesis: Materials from different teams rendered statistically significant effects in opposite directions for 4 of 5 hypotheses, with the narrowest range in estimates being d = -0.37 to + 0.26. Meta-analysis and a Bayesian perspective on the results revealed overall support for 2 hypotheses and a lack of support for 3 hypotheses. Overall, practically none of the variability in effect sizes was attributable to the skill of the research team in designing materials, whereas considerable variability was attributable to the hypothesis being tested. In a forecasting survey, predictions of other scientists were significantly correlated with study results, both across and within hypotheses. Crowdsourced testing of research hypotheses helps reveal the true consistency of empirical support for a scientific claim.
- Published
- 2020
32. Identification of further Craterostigma plantagineum cdt mutants affected in abscisic acid mediated desiccation tolerance
- Author
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Smith-Espinoza, C.J., Phillips, J.R., Salamini, F., and Bartels, D.
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- 2005
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33. Reverse genetic approaches in plants and yeast suggest a role for novel, evolutionarily conserved, selenoprotein-related genes in oxidative stress defense
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Rodrigo, M.-J., Moskovitz, J., Salamini, F., and Bartels, D.
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- 2002
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34. Rate constants and kinetic isotope effects in hydrogen abstractions by H from formic acid
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Lossack, A M, Bartels, D M, and ‡, E Roduner 1
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- 2001
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35. Building national estimates of the burden of road traffic injuries in developing countries from all available data sources: Iran
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Bhalla, K, Naghavi, M, Shahraz, S, Bartels, D, and Murray, C J L
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- 2009
- Full Text
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36. Evaluation of portal venous gas detected by ultrasound examination for diagnosis of necrotising enterocolitis
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Dördelmann, M, Rau, G A, Bartels, D, Linke, M, Derichs, N, Behrens, C, and Bohnhorst, B
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- 2009
- Full Text
- View/download PDF
37. Investigating the molecular basis of desiccation tolerance using the resurrection plant Craterostigma plantagineum as an experimental system
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Bartels, D., Chandler, J., Bockel, C., Frank, W., Kleines, M., Rodrigo, M. J., Phillips, J., Mariaux, J. -B., Furini, A., and Salamini, F.
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- 1997
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- View/download PDF
38. Structure and function of the vp1 gene homologue from the resurrection plant Craterostigma plantagineum Hochst.
- Author
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Chandler, J. W. and Bartels, D.
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- 1997
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39. Molecular genetics of desiccation and tolerant systems.
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Phillips, J. R., primary, Oliver, M. J., additional, and Bartels, D., additional
- Published
- 2002
- Full Text
- View/download PDF
40. Learning by Building (Destroying and Tinkering, Too): A Powerful Science Communication Tool
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Altmann, V., primary, Tamez, M., additional, and Bartels, D., additional
- Published
- 2001
- Full Text
- View/download PDF
41. Genetic Transformation of Craterostigma plantagineum
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Furini, A., primary, Salamini, F., additional, and Bartels, D., additional
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- 2001
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- View/download PDF
42. BRIGEP—the BRIDGE-based genome–transcriptome–proteome browser
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Goesmann, A., Linke, B., Bartels, D., Dondrup, M., Krause, L., Neuweger, H., Oehm, S., Paczian, T., Wilke, A., and Meyer, F.
- Published
- 2005
43. Population based study on the outcome of small for gestational age newborns
- Author
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Bartels, D B, Kreienbrock, L, Dammann, O, Wenzlaff, P, and Poets, C F
- Published
- 2005
44. Callus from the resurrection plant Craterostigma plantagineum is a versatile tool to study ABA-mediated gene expression
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Bartels, D., primary
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- 1999
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- View/download PDF
45. Messenger-RNA and protein changes associated with induction ofBrassica microspore embryogenesis
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Pechan, P. M., Bartels, D., Brown, D. C. W., and Schell, J.
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- 1991
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46. Messenger-RNA and protein changes associated with induction of Brassica microspore embryogenesis
- Author
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Pechan, P. M., Bartels, D., Brown, D. C. W., and Schell, J.
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- 1991
- Full Text
- View/download PDF
47. The Changing Landscape for Stroke Prevention in AF: Findings From the GLORIA-AF Registry Phase 2
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Huisman, M. V., Rothman, K. J., Paquette, M., Teutsch, C., Diener, H. -C., Dubner, S. J., Halperin, J. L., C. S., Ma, Zint, K., Elsaesser, A., Bartels, D. B., Lip, G. Y. H., Abban, D., Abdul, N., Abelson, M., Ackermann, A., Adams, F., Adams, L., Adragao, P., Ageno, W., Aggarwal, R., Agosti, S., Marin, J. A., Aguilar, F., Aguilar Linares, J. A., Aguinaga, L., Ahmad, Z., Ainsworth, P., Al Ghalayini, K., Al Ismail, S., Alasfar, A., Alawwa, A., Al-Dallow, R., Alderson, L., Alexopoulos, D., Ali, A., Ali, M., Aliyar, P., Al-Joundi, T., Al Mahameed, S., Almassi, H., Almuti, K., Al-Obaidi, M., Alshehri, M., Altmann, U., Alves, A. R., Al-Zoebi, A., Amara, W., Amelot, M., Amjadi, N., Ammirati, F., Andrawis, N., Angoulvant, D., Annoni, G., Ansalone, G., Antonescu, S. A., Ariani, M., Arias, J. C., Armero, S., Arora, R., Arora, C., Ashcraft, W., Aslam, M. S., Astesiano, A., Audouin, P., Augenbraun, C., Aydin, S., Azar, R., Azim, A., Aziz, S., Backes, L. M., Baig, M., Bains, S., Bakbak, A., Baker, S., Bakhtiar, K., Bala, R., Banayan, J., Bandh, S., Bando, S., Banerjee, S., Bank, A., Barbarash, O., Baron, G., Barr, C., Barrera, C., Barton, J., Kes, V. B., Baula, G., Bayeh, H., Bazargani, N., Behrens, S., Bell, A., Benezet-Mazuecos, J., Benhalima, B., Berdague, P., Berg van den, B. J., Bergen van, P. F. M. M., Berngard, E., Bernstein, R., Berrospi, P., Berti, S., Bertomeu, V., Berz, A., Bettencourt, P., Betzu, R., Beyer-Westendorf, J., Bhagwat, R., Black, T., Blanco Ibaceta, J. H., Bloom, S., Blumberg, E., Bo, M., Bockisch, V., Bohmer, E., Bongiorni, M. G., Boriani, G., Bosch, R., Boswijk, D. J., Bott, J., Bottacchi, E., Kalan, M. B., Brandes, A., Bratland, B., Brautigam, D., Breton, N., Brouwers, P. J. A. M., Browne, K., Bruguera, J., Brunehaut, M., Brunschwig, C., Buathier, H., Buhl, A., Bullinga, J., Butcher, K., Cabrera Honorio, J. W., Caccavo, A., Cadinot, D., Cai, S., Calvi, V., Camm, J., Candeias, R., Capo, J., Capucci, A., Cardoso, J. N., Duarte Vera, Y. C., Carlson, B., Carvalho, P., Cary, S., Casanova, R., Casu, G., Cattan, S., Cavallini, C., Cayla, G., Cha, T. J., Cha, K. S., Chaaban, S., Chae, J. K., Challappa, K., Chand, S., Chandrashekar, H., Chang, M., Charbel, P., Chartier, L., Chatterjee, K., Cheema, A., Chen, S. -A., Chevallereau, P., Chiang, F. -T., Chiarella, F., Chih-Chan, L., Cho, Y. K., Choi, D. J., Chouinard, G., Danny, Chow, H. F., Chrysos, D., Chumakova, G., Jose Roberto Chuquiure Valenzuela, E. J., Cieza-Lara, T., Nica, V. C., Ciobotaru, V., Cislowski, D., Citerne, O., Claus, M., Clay, A., Clifford, P., Cohen, S., Cohen, A., Colivicchi, F., Collins, R., Compton, S., Connors, S., Conti, A., Buenostro, G. C., Coodley, G., Cooper, M., Corbett, L., Corey, O., Coronel, J., Corrigan, J., Cotrina Pereyra, R. Y., Cottin, Y., Coutu, B., Cracan, A., Crean, P., Crenshaw, J., Crijns, H. J. G. M., Crump, C., Cucher, F., Cudmore, D., Cui, L., Culp, J., Darius, H., Dary, P., Dascotte, O., Dauber, I., Davee, T., Davies, R., Davis, G., Davy, J. -M., Dayer, M., De La Briolle, A., de Mora, M., De Teresa, E., De Wolf, L., Decoulx, E., Deepak, S., Defaye, P., Del-Carpio Munoz, F., Brkljacic, D. D., Deluche, L., Destrac, S., Deumite, N. J., Di Legge, S., Dibon, O., Diemberger, I., Dillinger, J., Dionisio, P., Naydenov, S., Dotani, I., Dotcheva, E., D'Souza, A., Dubrey, S., Ducrocq, X., Dupljakov, D., Duthinh, V., Dutra, O. P., Dutta, D., Duvilla, N., Dy, J., Dziewas, R., Eaton, C., Eaves, W., Ebinger, M., Eck van, J. W. M., Edwards, T., Egocheaga, I., Ehrlich, C., Eisenberg, S., El Hallak, A., El Jabali, A., El Mahmoud, R., El Shahawy, M., Eldadah, Z., Elghelbazouri, F., Elhag, O., El-Hamdani, M., Elias, D., Ellery, A., El-Sayed, H., Elvan, A., Erickson, B., Espaliat, E., Essandoh, L., Everington, T., Evonich, R., Ezhov, A., Facila, L., Farsad, R., Fayard, M., Fedele, F., Gomes Ferreira, L. G., Ferreira, D., Santos, J. F., Ferrier, A., Finsen, A., First, B., Fisher, R., Floyd, J., Folk, T., Fonseca, C., Fonseca, L., Forman, S., Forsgren, M., Foster, M., Foster, N., Frais, M., Frandsen, B., Frappe, T., Freixa, R., French, W., Freydlin, M., Frickel, S., Fruntelata, A. G., Fujii, S., Fujino, Y., Fukunaga, H., Furukawa, Y., Gabelmann, M., Gabris, M., Gadsboll, N., Galin, P., Galinier, M., Ganim, R., Garcia, R., Quintana, A. G., Gartenlaub, O., Genz, C., Georger, F., Georges, J. -L., Georgeson, S., Ghanbasha, A., Giedrimas, E., Gierba, M., Gillespie, E., Giniger, A., Gkotsis, A., Gmehling, J., Gniot, J., Goethals, P., Goldberg, R., Goldmann, B., Goldscher, D., Golitsyn, S., Gomez Lopez, E. A., Gomez Mesa, J. E., Gonzalez, E., Cocina, E. G., Juanatey, C. G., Gorbunov, V., Gordon, B., Gorka, H., Gornick, C., Gorog, D., Goss, F., Gotte, A., Goube, P., Goudevenos, I., Goulden, D., Graham, B., Grande, A., Greco, C., Green, M., Greer, G., Gremmler, U., Grena, P., Grinshstein, Y., Grond, M., Gronda, E., Grondin, F., Gronefeld, G., Groot de, J. R., Guardigli, G., Guarnieri, T., Caiedo, C. G., Guignier, A., Gulizia, M., Gumbley, M., Gupta, D., Hack, T., Haerer, W., Hakas, J., Hall, C., Hampsey, J., Hananis, G., Hanbali, B., Handel, F., Hargrove, J., Hargroves, D., Harris, K., Hartley, D., Haruna, T., Hata, Y., Hayek, E., Healey, J., Hearne, S., Heggelund, G., Hemels, M. E. W., Hemery, Y., Henein, S., Henz, B., Her, S. -H., Hermany, P., Hernandes, M. E., Higashino, Y., Hill, M., Hisadome, T., Hishida, E., Hitchcock, J., Hoffer, E., Hoghton, M., Holmes, C., Hong, S. K., Houppe Nousse, M. -P., Howard, V., Hsu, L. F., Huang, C. -H., Huckins, D., Huehnergarth, K., Huizenga, A., Huntley, R., Hussein, G., Hwang, G. -S., Igbokidi, O., Iglesias, I., Ikpoh, M., Imberti, D., Ince, H., Indolfi, C., Ionova, T., Ip, J., Irles, D., Iseki, H., Ismail, Y., Israel, N., Isserman, S., Iteld, B., Ivanchura, G., Iyer, R., Iyer, V., Iza Villanueva, R. O., Jackson-Voyzey, E., Jaffrani, N., Jager, F., Jain, M., James, M., Jamon, Y., Jang, S. W., Pereira Jardim, C. A., Jarmukli, N., Jeanfreau, R., Jenkins, R., Jiang, X., Jiang, H., Jiang, T., Jiang, N., Jimenez, J., Jobe, R., Joffe, I., Johansson, B., Jones, N., Moura Jorge, J. C., Jouve, B., Jundi, M., Jung, W., Jung, B. C., Jung, K. T., Kabbani, S., Kabour, A., Kafkala, C., Kajiwara, K., Kalinina, L., Kampus, P., Kanda, J., Kapadia, S., Karim, A., Karolyi, L., Kashou, H., Kastrup, A., Katsivas, A., Kaufman, E., Kawai, K., Kawajiri, K., Kazmierski, J., Keeling, P., Kerfes, G. A., Kerr Saraiva, J. F., Ketova, G., Khaira, A., Khalid, M., Khludeeva, E., Khripun, A., Kim, D. I., Kim, D. K., Kim, N. H., Kim, K. S., Kim, Y. -H., Kim, J. B., Kim, J. S., Kinova, E., Klein, A., Kleinschnitz, C., Kmetzo, J., Kneller, G. L., Knezevic, A., Koch, S., Koenig, K., Angela Koh, S. M., Kohrmann, M., Koons, J., Korabathina, R., Korennova, O., Koschutnik, M., Kosinski, E., Kovacic, D., Kowalczyk, J., Koziolova, N., Kragten, J. A., Krause, L. U., Kreidieh, I., Krenning, B. J., Krishnaswamy, K., Krysiak, W., Kuck, K. -H., Kumar, S., Kumler, T., Kuniss, M., Kuo, J. -Y., Kuppers, A., Kurrelmeyer, K., Kwan, T., Kyo, E., Labovitz, A., Lacroix, A., Lam, A., Lanas Zanetti, F. T., Landau, C., Landini, G., Lang, W., Larsen, T. B., Laske, V., Lavandier, K., Law, N., Lee, M. H., Lee, D., Leitao, A., Lejay, D., Lelonek, M., Lenarczyk, R., Leprince, P., Lequeux, B., Leschke, M., Ley, N., Li, Z., Li, Y., Li, X., Li, W., Liang, J., Lieber, I., Lillestol, M., Limon Rodriguez, R. H., Lin, H., Lip, G., Litchfield, J., Liu, Z., Liu, X., Liu, Y., Liu, F., Liu, W., Llamas Esperon, G. A., Llisterri, J. L., Lo, T., Lo, E., Lobos, J. M., Lodde, B. -P., Loiselet, P., Lopez-Sendon, J., Lorga Filho, A. M., Lori, I., Luo, M., Lupovitch, S., Lyrer, P., Zuhairy, H. M., Ma, C., Ma, G., Ma, H., Madariaga, I., Maeno, K., Magnin, D., Mahmood, S., Mahood, K., Maid, G., Mainigi, S., Makaritsis, K., Maldonado Villalon, J. A., Malhotra, R., Malik, A., Mallecourt, C., Mallik, R., Manning, R., Manolis, A., Mantas, I., Manzur Jattin, F. G., Marcionni, N., Marin, F., Santana, A. M., Martinez, J., Martinez, L., Maskova, P., Hernandez, N. M., Matskeplishvili, S., Matsuda, K., Mavri, A., May, E., Mayer, N., Mazon, P., Mcclure, J., Mccormack, T., Mcgarity, W., Mcguire, M., Mcintyre, H., Mclaughlin, P., Mclaurin, B., Medina Palomino, F. A., Mehta, P., Mehzad, R., Meinel, A., Melandri, F., Mena, A., Meno, H., Menzies, D., Metcalf, K., Meyer, B., Miarka, J., Mibach, F., Michalski, D., Michel, P., Chreih, R. M., Mikdadi, G., Mikhail, M., Mikus, M., Milicic, D., Militaru, C., Miller, G., Milonas, C., Minescu, B., Mintale, I., Miralles, A., Mirault, T., Mistry, D., Mitchell, G., Miu, N. V., Miyamoto, N., Moccetti, T., Mohammed, A., Nor, A. M., Molina de Salazar, D. I., Molon, G., Molony, D., Mondillo, S., Mont, L., Moodley, R., Moore, R., Ribeiro Moreira, D. A., Mori, K., Moriarty, A., Morka, J., Moschos, N., Mota Gomes, M. A., Mousallem, N., Moya, A., Mugge, A., Mulhearn, T., Muller, J. -J., Muresan, C. M., Muse, D., Musial, W., Musumeci, F., Nadar, V., Nageh, T., Nair, P., Nakagawa, H., Nakamura, Y., Nakayama, T., Nam, K. -B., Napalkov, D., Natarajan, I., Nayak, H., Nechvatal, L., Neiman, J., Nerheim, P., Neuenschwander, F. C., Nishida, K., Nizov, A., Novikova, T., Novo, S., Nowalany-Kozielska, E., Nsah, E., Nunez Fragoso, J. C., Nyvad, O., de Los Rios Ibarra, M. O., O'Donnell, M., O'Donnell, P., D. J., Oh, Y. S., Oh, Daniel Oh, C. T., O'Hara, G., Oikonomou, K., Olalla, J. J., Olivari, Z., Oliver, R., Olympios, C., Osborne, J., Osca, J., Osman, R., Osunkoya, A., Padanilam, B., Panchenko, E., Pandey, A. S., Vicenzo de Paola, A. A., Paraschos, A., Pardell, H., Park, H. W., Park, J. S., Parkash, R., Parker, I., Parrens, E., Parris, R., Passamonti, E., Patel, J., Patel, R., Pentz, W. H., Persic, V., Perticone, F., Peters, P., Petkar, S., Pezo, L. F., Pham, D., Cao Phai, G. P., Phlaum, S., Pineau, J., Pineda-Velez, A., Pini, R., Pinter, A., Pinto, F., Pirelli, S., Pivac, N., Pizzini, A. M., Pocanic, D., Calin Podoleanu, C. G., Polanczyk, C. A., Polasek, P., Poljakovic, Z., Pollock, S., Polo, J., Poock, J., Poppert, H., Porro, Y., Pose, A., Poulain, F., Poulard, J. -E., Pouzar, J., Povolny, P., Pozzer, D., Pras, A., Prasad, N., Prevot, S., Protasov, K., Prunier, L., Puleo, J., Pye, M., Qaddoura, F., Quedillac, J. -M., Raev, D., Rahimi, S., Raisaro, A., Rama, B., Ranadive, N., Randall, K., Ranjith, N., Raposo, N., Rashid, H., Raters, C., Rauch-Kroehnert, U., Rebane, T., Regner, S., Renzi, M., Reyes Rocha, M. A., Reza, S., Ria, L., Richter, D., Rickli, H., Rickner, K., Rieker, W., Rigo, F., Ripoll, T., Fonteles Ritt, L. E., Roberts, D., Pascual, C. R., Briones, I. R., Reyes, H. R., Roelke, M., Roman, M., Romeo, F., Ronner, E., Ronziere, T., Rooyer, F. A., Rosenbaum, D., Roth, S., Rozkova, N., Rubacek, M., Rubalcava, F., Rubanenko, O., Rubin, A., Borret, M. R., Rybak, K., Sabbour, H., Morales, O. S., Sakai, T., Salacata, A., Salecker, I., Salem, A., Salfity, M., Salguero, R., Salvioni, A., Samson, M., Sanchez, G., Sandesara, C., Saporito, W. F., Sasaoka, T., Sattar, P., Savard, D., Scala, P. -J., Scemama, J., Schaupp, T., Schellinger, P., Scherr, C., Schmitz, K. -H., Schmitz, B., Schmitz, L., Schnitzler, R., Schnupp, S., Schoeniger, P., Schon, N., Schuster, S., Schwimmbeck, P., Seamark, C., Seebass, R., Seidl, K. -H., Seidman, B., Sek, J., Sekaran, L., Seko, Y., Sepulveda Varela, P. A., Sevilla, B., Shah, V., Shah, A., Shah, N., Shanes, J., Sharareh, A., Sharma, V. K., Shaw, L., Shimizu, Y., Shimomura, H., Shin, D. G., Shin, E. -S., Shite, J., Shoukfeh, M., Shoultz, C., Silver, F., Sime, I., Simmers, T. A., Singal, D., Singh, N., Siostrzonek, P., Sirajuddin, M., Skeppholm, M., Smadja, D., Smith, R., Smith, D., Soda, H., Sofley, C. W., Sokal, A., Sotolongo, R., de Souza, O. F., Sparby, J. 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J, Zimmermann, S, Zimmermann, R, Zukerman, L, and Zwaan van der, C
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Male ,oral anticoagulation ,Internationality ,Middle Aged ,registry ,Antithrombins ,Dabigatran ,Stroke ,Cross-Sectional Studies ,Fibrinolytic Agents ,Humans ,Female ,atrial fibrillation ,Prospective Studies ,Registries ,Cardiology and Cardiovascular Medicine ,Aged ,Atrial Fibrillation - Abstract
Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non–vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients’ baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age ≥75 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score ≥2; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701)
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- 2017
48. The Role of Sucrose-Phosphate Synthase and Sucrose Synthase in the Desiccation Tolerance of the Resurrection Plant, Craterostigma Plantagineum Hochst
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Ingram, J., primary, Gallagher, L., additional, Elster, R., additional, Bianchi, G., additional, and Bartels, D., additional
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- 1995
- Full Text
- View/download PDF
49. PBI46 IMPLEMENTATION OF ADALIMUMAB BIOSIMILARS IN DENMARK
- Author
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Jensen, T.B., primary, Traerup Andersen, J., additional, Kim, S.C., additional, Kjellberg, J., additional, Bartels, D., additional, Rolighed Christensen, H., additional, and Jimenez Solem, E., additional
- Published
- 2019
- Full Text
- View/download PDF
50. PNS116 COMPARATIVE PRICING POLICY ANALYSIS BETWEEN DENMARK AND FRANCE.
- Author
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Rodrigues, J., primary, Bartels, D., additional, Gundtoft, L., additional, Planel, M.P., additional, Sales, J.P., additional, and Behnk, T.A., additional
- Published
- 2019
- Full Text
- View/download PDF
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