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4. Alpha-fetoprotein and gamma-glutamyltransferase in patients with liver cirrhosis and hepatocellular carcinoma.

Author

Barrientos, Marcos Arango, Sierra, Santiago Naranjo, Aristizábal, Luz Adriana Ocampo, Maya, Octavio Germán Muñoz, Tobón, John Jairo Zuleta, Duque, Sergio Iván Hoyos, Arango, Gonzalo Correa, Navas, María Cristina Navas, and Gutiérrez, Juan Carlos Restrepo

Subjects
*ALPHA fetoproteins, *BLOOD proteins, *GLOBULINS, *TRANSFERASES, *TREATMENT of cirrhosis of the liver, *CANCER patients
Abstract

Introduction: Hepatocellular carcinoma (HCC) is one of the complications associated with liver cirrhosis (LC). The main objective of the present study was to describe the levels of the serological markers alpha-fetoprotein (AFP) and gamma-glutamyltranspeptidase (GGT) in patients with LC and/or HCC. Methods: Cross sectional study that included 99 patients with a diagnosis of LC and/or HCC. Results: 66 (66.7%) patients had a diagnosis of LC, 23 (23.2%) had LC alongside with HCC and 10 (10.1%) had HCC without LC. AFP levels were higher in individuals with HCC associated with LC when compared with those with LC only (20 and 2.93 ng/ mL, p <0.05), the levels of GGT were also higher in patients with HCC associated with LC (208 and 109 IU/L, p <0.05). Not a single patient with HCC had normal levels of AFP and GGT simultaneously. Conclusions: In patients with HCC associated with LC levels of AFP and GGT were significantly higher than those found in individuals with LC only. [ABSTRACT FROM AUTHOR]

Published
2010

5. Alfa-fetoproteína y gamma-glutamiltranspeptidasa en pacientes con cirrosis hepática y carcinoma hepatocelular.

Author

Barrientos, Marcos Arango, Sierra, Santiago Naranjo, Aristizábal, Luz Adriana Ocampo, Maya, Octavio Germán Muñoz, Tobón, John Jairo Zuleta, Duque, Sergio Iván Hoyos, Arango, Gonzalo Correa, Navas, María Cristina Navas, and Gutiérrez, Juan Carlos Restrepo

Subjects
*ALPHA fetoproteins, *TRANSFERASES, *ENZYMES, *CIRRHOSIS of the liver, *ALCOHOLISM, *LIVER cancer
Abstract

Introduction: Hepatocellular carcinoma (HCC) is one of the complications associated with liver cirrhosis (LC). The main objective of the present study was to describe the levels of the serological markers alpha-fetoprotein (AFP) and gamma-glutamyltranspeptidase (GGT) in patients with LC and/or HCC. Methods: Cross sectional study that included 99 patients with a diagnosis of LC and/or HCC. Results: 66 (66.7%) patients had a diagnosis of LC, 23 (23.2%) had LC alongside with HCC and 10 (10.1%) had HCC without LC. AFP levels were higher in individuals with HCC associated with LC when compared with those with LC only (20 and 2.93 ng/ mL, p <0.05), the levels of GGT were also higher in patients with HCC associated with LC (208 and 109 IU/L, p <0.05). Not a single patient with HCC had normal levels of AFP and GGT simultaneously. Conclusions: In patients with HCC associated with LC levels of AFP and GGT were significantly higher than those found in individuals with LC only. [ABSTRACT FROM AUTHOR]

Published
2010

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