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2. Prognostic implications of thyroid disease in patients with atrial fibrillation

Author

Vasilopoulou, Anthi, Patsiou, Vasiliki, Bekiaridou, Alexandra, Papazoglou, Andreas S., Moysidis, Dimitrios V., Spaho, Marina, Zergioti, Martha, Kostakakis, Dimitrios, Kyriakideli, Maria-Eirini, Lampropoulou, Chrysanthi-Ioanna, Kartas, Anastasios, Samaras, Athanasios, Baroutidou, Amalia, Tzikas, Apostolos, Ziakas, Antonios, and Giannakoulas, George

Published
2024
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6. Use of apixaban in adults with congenital heart disease and atrial arrhythmias: The PROTECT-AR study

Author

Kartas, Anastasios, Papazoglou, Andreas S., Moysidis, Dimitrios V., Despotopoulos, Stefanos, Baroutidou, Amalia, Kosmidis, Diamantis, Koutsakis, Athanasios, Liori, Sotiria, Apostolopoulou, Sotiria, Frogoudaki, Alexandra, Tzifa, Afrodite, Galatas, Apostolos, Alexandridis, Georgios, Spiridonidis, Efstathios, Doundoulakis, Ioannis, Karagiannidis, Efstratios, Karvounis, Haralambos, Ziakas, Antonios, and Giannakoulas, George

Published
2024
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7. Abstract 15341: A Prospective Study on the Safety and Effectiveness of Apixaban for the Prevention of Thromboembolism in Adults With Congenital Heart Disease and Atrial Arrhythmias: The PROTECT-AR Study

Author

Kartas, Anastasios, Papazoglou, Andreas, Moysidis, Dimitrios, Despotopoulos, Stefanos, Kosmidis, Diamantis, Baroutidou, Amalia, Koutsakis, Athanasios, Liori, Sotiria, Apostolopoulou, Sotiria, Frogoudaki, Alexandra, Tzifa, Afrodite, Galatas, Apostolos, ALEXANDRIDIS, GEORGIOS, Spyridonidis, Efstathios, Doundoulakis, Ioannis, KARAGIANNIDIS, EFSTRATIOS, Karvounis, Charalampos I, Ziakas, Antonios, and Giannakoulas, George

Published
2023
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10. Prescription rates and prognostic implications of optimally-targeted guideline-directed medical treatment in heart failure and atrial fibrillation Insights from the MISOAC-AF trial

Author

Moysidis, Dimitrios V., Kartas, Anastasios, Samaras, Athanasios, Papazoglou, Andreas S., Patsiou, Vasiliki, Αlexandra Bekiaridou, Baroutidou, Amalia, Tsagkaris, Christos, Karagiannidis, Efstratios, Daios, Stylianos, Anastasiou, Vasileios, Tsalikakis, Dimitrios, Efthimiadis, Georgios, Ziakas, Antonios, Tzikas, Apostolos, and Giannakoulas, George

Published
2022
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11. Polypharmacy and Major Adverse Events in Atrial Fibrillation

Author

Tsagkaris, Christos, Papazoglou, Andreas S., Kartas, Anastasios, Samaras, Athanasios, Moysidis, Dimitrios V., Vouloagkas, Ioannis, Baroutidou, Amalia, Bekiaridou, Alexandra, Patsiou, Vasiliki, Chatzisolomou, Antreas, Panteris, Eleftherios, Karagiannidis, Efstratios, Karvounis, Haralambos, Tzikas, Apostolos, and Giannakoulas, George

Published
2022
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12. ACE Inhibitor and Angiotensin Receptor Blocker Use During Pregnancy:Data from the ESC Registry Of Pregnancy and Cardiac Disease (ROPAC)

Author

van der Zande, Johanna A., Ramlakhan, Karishma P., Prokselj, Katja, Muñoz-Ortiz, Edison, Baroutidou, Amalia, Lipczynska, Magdalena, Nagy, Edit, Rutz, Tobias, Franx, Arie, Hall, Roger, Johnson, Mark R., Roos-Hesselink, Jolien W., van der Zande, Johanna A., Ramlakhan, Karishma P., Prokselj, Katja, Muñoz-Ortiz, Edison, Baroutidou, Amalia, Lipczynska, Magdalena, Nagy, Edit, Rutz, Tobias, Franx, Arie, Hall, Roger, Johnson, Mark R., and Roos-Hesselink, Jolien W.

Abstract

Angiotensin-converting enzyme inhibitors (ACE-Is) and angiotensin receptor blockers (ARBs) are not recommended during the second and third trimester because of the significant risk of congenital anomalies associated with their use. However, data are scarce, especially regarding their use in the first trimester and about the impact of stopping just before pregnancy. Our study illustrates the profile of the women who used ACE-Is or ARBs during pregnancy and evaluates the impact on perinatal outcomes. The Registry of Pregnancy and Cardiac Disease is a prospective, global registry of pregnancies in women with structural heart disease. Outcomes were compared between women who used ACE-Is or ARBs and those who did not. Multivariable regression analysis was performed to assess the effect of ACE-I or ARB use on the occurrence of congenital anomalies. ACE-Is (n = 35) and/or ARBs (n = 8) were used in 42 (0.7%) of the 5,739 Registry of Pregnancy and Cardiac Disease pregnancies. Women who used ACE-Is or ARBs more often came from a low-or-middle-income country (57% vs 40%, p = 0.021), had chronic hypertension (31% vs 6%, p <0.001), or a left ventricular ejection fraction <40% (33% vs 4%, p <0.001). In the multivariable analysis, ACE-I use during the first trimester was associated with an increased risk of congenital anomaly (odds ratio 3.2, 95% confidence interval 1.0 to 9.6). Therefore, ACE-Is should be avoided during pregnancy, also in the first trimester, because of a higher risk of congenital anomalies. However, there is no need to stop long before pregnancy. Preconception counseling is crucial to discuss the potential risks of these medications, to evaluate the clinical condition and, if possible, to change or stop the medication.

Published
2024

13. Speckle Tracking Echocardiography in Patients with Non-Ischemic Dilated Cardiomyopathy Who Undergo Cardiac Resynchronization Therapy: A Narrative Review.

Author

Antoniou, Nikolaos, Kalaitzoglou, Maria, Tsigkriki, Lamprini, Baroutidou, Amalia, Tsaousidis, Adam, Koulaouzidis, George, Giannakoulas, George, and Charisopoulou, Dafni

Subjects
SPECKLE tracking echocardiography, ECHOCARDIOGRAPHY, NARRATIVE therapy, DILATED cardiomyopathy, PATIENT selection, CARDIAC pacing
Abstract

Non-ischemic dilated cardiomyopathy (DCM) represents a significant cause of heart failure, defined as the presence of left ventricular (LV) dilatation and systolic dysfunction unexplained solely by abnormal loading conditions or coronary artery disease. Cardiac resynchronization therapy (CRT) has emerged as a cornerstone in the management of heart failure, particularly in patients with DCM. However, identifying patients who will benefit the most from CRT remains challenging. Speckle tracking echocardiography (STE) has garnered attention as a non-invasive imaging modality that allows for the quantitative assessment of myocardial mechanics, offering insights into LV function beyond traditional echocardiographic parameters. This comprehensive review explores the role of STE in guiding patient selection and optimizing outcomes in CRT for DCM. By assessing parameters such as LV strain, strain rate, and dyssynchrony, STE enables a more precise evaluation of myocardial function and mechanical dyssynchrony, aiding in the identification of patients who are most likely to benefit from CRT. Furthermore, STE provides valuable prognostic information and facilitates post-CRT optimization by guiding lead placement and assessing response to therapy. Through an integration of STE with CRT, clinicians can enhance patient selection, improve procedural success rates, and ultimately, optimize clinical outcomes in patients with DCM. This review underscores the pivotal role of STE in advancing personalized management strategies for DCM patients undergoing CRT. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Renal function and mortality in patients with atrial fibrillation

Author

Liampas, Evangelos, Kartas, Anastasios, Samaras, Athanasios, Papazoglou, Andreas S., Moysidis, Dimitrios V., Vrana, Eleni, Botis, Michail, Papanastasiou, Anastasios, Baroutidou, Amalia, Vouloagkas, Ioannis, Karagiannidis, Efstratios, Akrivos, Evangelos, Tsalikakis, Dimitrios, Fyntanidou, Varvara, Karvounis, Haralambos, Tzikas, Apostolos, and Giannakoulas, George

Published
2022
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17. Prognostic implications of thyroid disease in patients with atrial fibrillation

Author

Vasilopoulou, Anthi, primary, Patsiou, Vasiliki, additional, Bekiaridou, Alexandra, additional, Papazoglou, Andreas S., additional, Moysidis, Dimitrios V., additional, Spaho, Marina, additional, Zergioti, Martha, additional, Kostakakis, Dimitrios, additional, Kyriakideli, Maria-Eirini, additional, Lampropoulou, Chrysanthi-Ioanna, additional, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Baroutidou, Amalia, additional, Tzikas, Apostolos, additional, Ziakas, Antonios, additional, and Giannakoulas, George, additional

Published
2023
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18. Contribution of pressure and flow changes to resistance reduction after pulmonary arterial hypertension treatment: a meta-analysis of 3898 patients

Author

Farmakis, Ioannis T., primary, Baroutidou, Amalia, additional, Patsiou, Vasiliki, additional, Arvanitaki, Alexandra, additional, Doundoulakis, Ioannis, additional, Hobohm, Lukas, additional, Zafeiropoulos, Stefanos, additional, Konstantinides, Stavros V, additional, D'Alto, Michele, additional, Badagliacca, Roberto, additional, and Giannakoulas, George, additional

Published
2023
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19. Prognostic significance of diabetes mellitus in patients with atrial fibrillation

Author

Papazoglou, Andreas S., Kartas, Anastasios, Samaras, Athanasios, Vouloagkas, Ioannis, Vrana, Eleni, Moysidis, Dimitrios V., Akrivos, Evangelos, Kotzampasis, Georgios, Baroutidou, Amalia, Papanastasiou, Anastasios, Liampas, Evangelos, Botis, Michail, Karagiannidis, Efstratios, Stalikas, Nikolaos, Karvounis, Haralambos, Tzikas, Apostolos, and Giannakoulas, George

Published
2021
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23. Cardioselective versus Non-Cardioselective Beta-Blockers and Outcomes in Patients with Atrial Fibrillation and Chronic Obstructive Pulmonary Disease

Author

Vlachopoulou, Dimitra, primary, Balomenakis, Charalampos, additional, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Papazoglou, Andreas S., additional, Moysidis, Dimitrios V., additional, Barmpagiannos, Konstantinos, additional, Kyriakou, Melina, additional, Papanastasiou, Anastasios, additional, Baroutidou, Amalia, additional, Vouloagkas, Ioannis, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2023
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24. Prognostic implications of adherence to oral anticoagulants among patients with atrial fibrillation: Insights from MISOAC-AF trial

Author

Patsiou, Vasiliki, primary, Samaras, Athanasios, additional, Kartas, Anastasios, additional, Moysidis, Dimitrios V., additional, Papazoglou, Andreas S., additional, Bekiaridou, Alexandra, additional, Baroutidou, Amalia, additional, Ziakas, Antonios, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2023
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25. Prescription Rates and Prognostic Implications of Optimally Targeted Guideline-Directed Medical Treatment in Heart Failure and Atrial Fibrillation: Insights From The MISOAC-AF Trial

Author

Moysidis, Dimitrios V., primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Papazoglou, Andreas S., additional, Patsiou, Vasiliki, additional, Bekiaridou, Alexandra, additional, Baroutidou, Amalia, additional, Tsagkaris, Christos, additional, Karagiannidis, Efstratios, additional, Daios, Stylianos, additional, Anastasiou, Vasileios, additional, Tsalikakis, Dimitrios, additional, Efthimiadis, Georgios, additional, Ziakas, Antonios, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2023
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26. Clinical outcomes in patients with atrial fibrillation treated with digoxin, according to the presence of heart failure: Insights from the MISOAC-AF trial

Author

Botis, Michail, primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Akrivos, Evangelos, additional, Vrana, Elena, additional, Liampas, Evangelos, additional, Papazoglou, Andreas S., additional, Moysidis, Dimitrios V., additional, Papanastasiou, Anastasios, additional, Baroutidou, Amalia, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, Parissis, John, additional, Drakos, Stavros G., additional, and Giannakoulas, George, additional

Published
2022
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27. Association of Health Status Metrics with Clinical Outcomes in Patients with Adult Congenital Heart Disease and Atrial Arrhythmias

Author

Baroutidou, Amalia, primary, Kartas, Anastasios, additional, Papazoglou, Andreas S., additional, Kosmidis, Diamantis, additional, Moysidis, Dimitrios V., additional, Otountzidis, Nikolaos, additional, Doundoulakis, Ioannis, additional, Despotopoulos, Stefanos, additional, Vrana, Elena, additional, Koutsakis, Athanasios, additional, Rampidis, Georgios P., additional, Ntiloudi, Despoina, additional, Liori, Sotiria, additional, Avramidis, Dimosthenis, additional, Karagiannidis, Efstratios, additional, Nikolopoulos, Theodoros Thomas, additional, Apostolopoulou, Sotiria, additional, Frogoudaki, Alexandra, additional, Tzifa, Afrodite, additional, Karvounis, Haralambos, additional, and Giannakoulas, George, additional

Published
2022
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29. Rhythm control versus rate control in patients with atrial fibrillation and heart failure across the left ventricular ejection fraction spectrum

Author

Moysidis, Dimitrios V., primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Papazoglou, Andreas S., additional, Akrivos, Evangelos, additional, Vouloagkas, Ioannis, additional, Papanastasiou, Anastasios, additional, Vrana, Eleni, additional, Baroutidou, Amalia, additional, Botis, Michail, additional, Liampas, Evangelos, additional, Tsagkaris, Christos, additional, Karagiannidis, Efstratios, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2022
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31. Education level predicts mortality and morbidity in hospitalised patients with atrial fibrillation

Author

Patsiou, Vasiliki, primary, Moysidis, Dimitrios V., additional, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Papazoglou, Andreas S., additional, Bekiaridou, Alexandra, additional, Tsagkaris, Christos, additional, Vouloagkas, Ioannis, additional, Loudovikou, Anna, additional, Papanastasiou, Anastasios, additional, Vrana, Eleni, additional, Baroutidou, Amalia, additional, Botis, Michail, additional, Liampas, Evangelos, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2022
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32. Potent P2Y12 inhibitors versus clopidogrel to predict adherence to antiplatelet therapy after an acute coronary syndrome: insights from IDEAL-LDL

Author

Kourti, Olga, primary, Konstantas, Orestis, primary, Farmakis, Ioannis Τ, primary, Zafeiropoulos, Stefanos, primary, Psarakis, Georgios, primary, Vrana, Elena, primary, Baroutidou, Amalia, primary, Graidis, Spyridon, primary, Touriki, Aikaterini-Vassiliki, primary, Tsolakidis, Christos, primary, Spyridaki, Konstantina, primary, Psathas, Thomas, primary, Daniilidou, Anastasia, primary, Karvounis, Haralambos, primary, and Giannakoulas, George, primary

Published
2022
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33. Supplemental Material, sj-docx-1-cpt-10.1177_10742484211069422 - Associations of Atrial Fibrillation Patterns With Mortality and Cardiovascular Events: Implications of the MISOAC-AF Trial

Author

Baroutidou, Amalia, Kartas, Anastasios, Samaras, Athanasios, Papazoglou, Andreas S., Vrana, Eleni, Moysidis, Dimitrios V., Akrivos, Evangelos, Papanastasiou, Anastasios, Vouloagkas, Ioannis, Botis, Michail, Liampas, Evangelos, Karagiannidis, Artemios G., Karagiannidis, Efstratios, Efthimiadis, Georgios, Karvounis, Haralambos, Tzikas, Apostolos, and Giannakoulas, George

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, Cardiology, 110323 Surgery, 110306 Endocrinology, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
Abstract

Supplemental Material, sj-docx-1-cpt-10.1177_10742484211069422 for Associations of Atrial Fibrillation Patterns With Mortality and Cardiovascular Events: Implications of the MISOAC-AF Trial by Amalia Baroutidou, Anastasios Kartas, Athanasios Samaras, Andreas S. Papazoglou, Eleni Vrana, Dimitrios V. Moysidis, Evangelos Akrivos, Anastasios Papanastasiou, Ioannis Vouloagkas, Michail Botis, Evangelos Liampas, Artemios G. Karagiannidis, Efstratios Karagiannidis, Georgios Efthimiadis, Haralambos Karvounis, Apostolos Tzikas and George Giannakoulas in Journal of Cardiovascular Pharmacology and Therapeutics

Published
2022
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34. The Adult Congenital Heart Disease Anatomic and Physiological Classification: Associations with Clinical Outcomes in Patients with Atrial Arrhythmias

Author

Kartas, Anastasios, primary, Papazoglou, Andreas S., additional, Kosmidis, Diamantis, additional, Moysidis, Dimitrios V., additional, Baroutidou, Amalia, additional, Doundoulakis, Ioannis, additional, Despotopoulos, Stefanos, additional, Vrana, Elena, additional, Koutsakis, Athanasios, additional, Rampidis, Georgios P., additional, Ntiloudi, Despoina, additional, Liori, Sotiria, additional, Mousiama, Tereza, additional, Avramidis, Dimosthenis, additional, Apostolopoulou, Sotiria, additional, Frogoudaki, Alexandra, additional, Tzifa, Afrodite, additional, Karvounis, Haralambos, additional, and Giannakoulas, George, additional

Published
2022
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36. Associations of Atrial Fibrillation Patterns With Mortality and Cardiovascular Events: Implications of the MISOAC-AF Trial

Author

Baroutidou, Amalia, primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Papazoglou, Andreas S., additional, Vrana, Eleni, additional, Moysidis, Dimitrios V., additional, Akrivos, Evangelos, additional, Papanastasiou, Anastasios, additional, Vouloagkas, Ioannis, additional, Botis, Michail, additional, Liampas, Evangelos, additional, Karagiannidis, Artemios G., additional, Karagiannidis, Efstratios, additional, Efthimiadis, Georgios, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2022
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37. Predictive Role of Platelet-Associated Indices on Admission and Discharge in the Long-Term Prognosis of Acute Coronary Syndrome Patients

Author

Psarakis, Georgios, primary, Farmakis, Ioannis, additional, Zafeiropoulos, Stefanos, additional, Kourti, Olga, additional, Konstantas, Orestis, additional, Vrana, Eleni, additional, Baroutidou, Amalia, additional, Tsolakidis, Christos, additional, Touriki, Aikaterini-Vassiliki, additional, Psathas, Thomas, additional, Graidis, Spyridon, additional, Spyridaki, Konstantina, additional, Daniilidou, Anastasia, additional, Tsakiridis, Konstantinos, additional, Tsalikakis, Dimitrios, additional, Skoura, Lemonia, additional, Karvounis, Haralambos, additional, and Giannakoulas, George, additional

Published
2021
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38. Oral anticoagulation patterns and prognosis in octogenarian patients with atrial fibrillation

Author

Papanastasiou, Anastasios, primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Vrana, Eleni, additional, Papazoglou, Andreas, additional, Moysidis, Dimitrios V., additional, Baroutidou, Amalia, additional, Botis, Michail, additional, Liampas, Evaggelos, additional, Vouloagkas, Ioannis, additional, Mareti, Evangelia, additional, Karagiannidis, Efstratios, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2021
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39. Gender-Related Differences In Treatment Patterns And Outcomes of Patients With Atrial Fibrillation: Insights From The MISOAC-AF Trial

Author

Vouloagkas, Ioannis, primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Papazoglou, Andreas S., additional, Moysidis, Dimitrios V., additional, Vrana, Eleni, additional, Papanastasiou, Anastasios, additional, Baroutidou, Amalia, additional, Botis, Michail, additional, Kotzampasis, Georgios, additional, Liampas, Evangelos, additional, Zegkos, Thomas, additional, Mouratoglou, Sophia Anastasia, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2021
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40. Τhe association of heart failure across left ventricular ejection fraction with mortality in atrial fibrillation

Author

Kartas, Anastasios, primary, Samaras, Athanasios, additional, Akrivos, Evangelos, additional, Vrana, Eleni, additional, Papazoglou, Andreas S., additional, Moysidis, Dimitrios V., additional, Papanastasiou, Anastasios, additional, Baroutidou, Amalia, additional, Botis, Michail, additional, Liampas, Evangelos, additional, Vouloagkas, Ioannis, additional, Karagiannidis, Efstratios, additional, Karvounis, Haralambos, additional, Parissis, John, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2021
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41. sj-pdf-1-ang-10.1177_00033197211052134 ��� Supplemental Material for Predictive Role of Platelet-Associated Indices on Admission and Discharge in the Long-Term Prognosis of Acute Coronary Syndrome Patients

Author

Psarakis, Georgios, Farmakis, Ioannis, Zafeiropoulos, Stefanos, Kourti, Olga, Konstantas, Orestis, Vrana, Eleni, Baroutidou, Amalia, Tsolakidis, Christos, Touriki, Aikaterini-Vassiliki, Psathas, Thomas, Graidis, Spyridon, Spyridaki, Konstantina, Daniilidou, Anastasia, Tsakiridis, Konstantinos, Tsalikakis, Dimitrios, Skoura, Lemonia, Karvounis, Haralambos, and Giannakoulas, George

Subjects
Cardiology
Abstract

Supplemental Material, sj-pdf-1-ang-10.1177_00033197211052134 for Predictive Role of Platelet-Associated Indices on Admission and Discharge in the Long-Term Prognosis of Acute Coronary Syndrome Patients by Georgios Psarakis, Ioannis Farmakis, Stefanos Zafeiropoulos, Olga Kourti, Orestis Konstantas, Eleni Vrana, Amalia Baroutidou, Christos Tsolakidis, Aikaterini-Vassiliki Touriki, Thomas Psathas, Spyridon Graidis, Konstantina Spyridaki, Anastasia Daniilidou, Konstantinos Tsakiridis, Dimitrios Tsalikakis, Lemonia Skoura, Haralambos Karvounis and George Giannakoulas in Angiology

Published
2021
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42. Prognostic significance of diabetes mellitus in patients with atrial fibrillation

Author

Papazoglou, Andreas S, primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Akrivos, Evangelos, additional, Vouloagkas, Ioannis, additional, Vrana, Eleni, additional, Moysidis, Dimitrios V, additional, Kotzampasis, Georgios, additional, Baroutidou, Amalia, additional, Papanastasiou, Anastasios, additional, Liampas, Evangelos, additional, Botis, Michail, additional, Karagiannidis, Efstratios, additional, Stalikas, Nikolaos, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2021
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43. Prognostic Significance of Diabetes Mellitus in Patients with Atrial Fibrillation

Author

Papazoglou, Andreas S, primary, Kartas, Anastasios, additional, Samaras, Athanasios, additional, Akrivos, Evangelos, additional, Vouloagkas, Ioannis, additional, Vrana, Eleni, additional, Moysidis, Dimitrios V, additional, Kotzampasis, Georgios, additional, Baroutidou, Amalia, additional, Papanastasiou, Anastasios, additional, Liampas, Evangelos, additional, Botis, Michail, additional, Karagiannidis, Efstratios, additional, Stalikas, Nikolaos, additional, Karvounis, Haralambos, additional, Tzikas, Apostolos, additional, and Giannakoulas, George, additional

Published
2020
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44. Predictive Role of Platelet-Associated Indices on Admission and Discharge in the Long-Term Prognosis of Acute Coronary Syndrome Patients.

Author

Psarakis, Georgios, Farmakis, Ioannis, Zafeiropoulos, Stefanos, Kourti, Olga, Konstantas, Orestis, Vrana, Eleni, Baroutidou, Amalia, Tsolakidis, Christos, Touriki, Aikaterini-Vassiliki, Psathas, Thomas, Graidis, Spyridon, Spyridaki, Konstantina, Daniilidou, Anastasia, Tsakiridis, Konstantinos, Tsalikakis, Dimitrios, Skoura, Lemonia, Karvounis, Haralambos, and Giannakoulas, George

Subjects
STATISTICS, CONFIDENCE intervals, BLOOD platelets, MULTIVARIATE analysis, ACUTE coronary syndrome, PATIENTS, HOSPITAL admission & discharge, SEVERITY of illness index, SURVIVAL analysis (Biometry), PLATELET count, HOSPITAL care, PREDICTIVE validity, ADVERSE health care events, DISCHARGE planning, MEAN platelet volume
Abstract

Our study aimed to investigate the association between platelet indices and their in-hospital change and long-term prognosis in acute coronary syndrome (ACS). Data from a randomized controlled trial (NCT02927808) recruiting ACS patients were analyzed (survival analysis). The examined variables were platelet count (PC), mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) on admission and discharge, as well as their alteration during hospitalization. The primary endpoint was major adverse cardiac events (MACE) (cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke or hospitalization for unstable angina) and all-cause mortality, while secondary endpoints were all-cause hospitalization and bleeding events. The study included 252 patients with a follow-up of 39 (28–45) months. In the univariate analysis, MACE was associated with discharge PC [hazard ratio (HR) 2.20, 95% confidence interval (CI) 1.10–4.40], discharge MPV (HR 0.48, 95% CI 0.25–0.94), and in-hospital PC difference (HR 0.25, 95% CI 0.13–0.51). In the multivariable analysis, only in-hospital PC decrease correlated with lower MACE incidence (adjusted HR.27, 95% CI 0.14–0.54) and lower all-cause hospitalization risk (adjusted HR 0.36, 95% CI 0.19–0.68). PC reduction during hospitalization for ACS is an independent predictor of better prognosis. [ABSTRACT FROM AUTHOR]

Published
2022
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45. Nailfold videocapillaroscopy as a non-invasive tool for the assessment of peripheral microangiopathy in cardiovascular diseases.

Author

Baroutidou A, Arvanitaki A, Pagkopoulou E, Anyfanti P, Ziakas A, Kamperidis V, Giannakoulas G, and Dimitroulas T

Abstract

Cardiovascular disease (CVD) remains the main cause of morbidity and mortality worldwide. Accumulating evidence supports the presence of endothelial and microvascular dysfunction in CVD, which can be assessed using several methods in peripheral organs and tissues. Naifold videocapillaroscopy (NVC) is an established, noninvasive, easily applicable technique for the assessment of peripheral microcirculation. There is limited capillaroscopic data in the field of CVD, though, and the diagnostic or possible prognostic significance of the capillaroscopic alterations in this population is still a matter of research. This review aims to summarize the current knowledge on the capillaroscopic findings in patients with cardiovascular risk factors or established atherosclerotic and nonatherosclerotic CVD, focusing on the possible correlations of these alterations with clinical and laboratory markers of cardiac function., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Published
2024
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