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6. High extracellular sodium chloride concentrations induce resistance to LPS signal in human dendritic cells

Author

Al-Hajj, Sally, primary, Lemoine, Roxane, additional, Chadet, Stéphanie, additional, Goumard, Annabelle, additional, Legay, Laura, additional, Roxburgh, Ellena, additional, Heraud, Audrey, additional, Deluce, Nora, additional, Lamendour, Lucille, additional, Burlaud-Gaillard, Julien, additional, Gatault, Philippe, additional, Büchler, Mathias, additional, Roger, Sébastien, additional, Halimi, Jean-Michel, additional, and Baron, Christophe, additional

Published
2023
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13. THE VOLTAGE-GATED SODIUM CHANNEL BETA4 SUBUNIT MAINTAINS EPITHELIAL PHENOTYPE IN MAMMARY CELLS

Author

Doray, Adélaïde, Lemoine, Roxane, Severin, Marc, Chadet, Stéphanie, Lopez-Charcas, Osbaldo, Héraud, Audrey, Baron, Christophe, Besson, Pierre, Monteil, Arnaud, Pedersen, Stine Falsig, Roger, Sébastien, EA4245 - Transplantation, Immunologie, Inflammation [Tours] (T2i), Université de Tours (UT), University of Copenhagen = Københavns Universitet (KU), Institut de Génomique Fonctionnelle (IGF), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.), Université de Tours, University of Copenhagen = Københavns Universitet (UCPH), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), and Monteil, Arnaud

Subjects
QH301-705.5, [SDV]Life Sciences [q-bio], NaVβ4, Down-Regulation, Article, Cell Line, Mesoderm, Mammary Glands, Animal, Epithelial-to-Mesenchymal Transition, Animals, Humans, Biology (General), beta Catenin, Voltage-Gated Sodium Channel beta-4 Subunit, Cell Polarity, Epithelial Cells, β-catenin, [SDV] Life Sciences [q-bio], Protein Subunits, Phenotype, Proteolysis, Female, mammary cells Powered by Editorial Manager® and ProduXion Manager® from Aries Systems Corporation, epithelial-to-mesenchymal transition, mammary cells, epithelial phenotype
Abstract

The SCN4B gene, coding for the NaVβ4 subunit of voltage-gated sodium channels, was recently found to be expressed in normal epithelial cells and down-regulated in several cancers. However, its function in normal epithelial cells has not been characterized. In this study, we demonstrated that reducing NaVβ4 expression in MCF10A non-cancer mammary epithelial cells generated important morphological changes observed both in two-dimensional cultures and in three-dimensional cysts. Most notably, the loss of NaVβ4 induced a complete loss of epithelial organisation in cysts and increased proteolytic activity towards the extracellular matrix. Loss of epithelial morphology was associated with an increased degradation of β-catenin, reduced E-cadherin expression and induction of mesenchymal markers N-cadherin, vimentin, and α-SMA expression. Overall, our results suggest that Navβ4 may participate in the maintenance of the epithelial phenotype in mammary cells and that its downregulation might be a determining step in early carcinogenesis.

Published
2021

24. Association between polymorphism in the human programmed death-1 (PD-1) gene and cytomegalovirus infection after kidney transplantation

Author

Hoffmann, Thomas W., Halimi, Jean-Michel, Buchler, Mathias, Velge-Roussel, Florence, Goudeau, Alain, Al-Najjar, Azmi, Marliere, Jean-Frederic, Lebranchu, Yvon, and Baron, Christophe

Subjects
Genetic polymorphisms -- Research, Cytomegalovirus infections -- Genetic aspects, Cytomegalovirus infections -- Risk factors, Cytomegalovirus infections -- Research, Apoptosis -- Genetic aspects, Apoptosis -- Research, Kidneys -- Transplantation, Kidneys -- Complications and side effects, Kidneys -- Research, Health
Published
2010

27. Les mécanismes de l’alloréactivité, des rejets de greffe et de la réaction du greffon contre l’hôte. Chapitre 27

Author

Blancho, Gilles, de Carvalho-Bittencourt, Marcelo, Baron, Christophe, Labalette, Myriam, Moins-Teisserenc, Hélène, Sterkers, Ghislaine, Tiberghien, Pierre, Centre hospitalier universitaire de Nantes (CHU Nantes), Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Université de Tours (UT), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Lille, Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), AP-HP Hôpital universitaire Robert-Debré [Paris], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC), and DE CARVALHO, MARCELO

Subjects
[SDV.IMM] Life Sciences [q-bio]/Immunology, [SDV.IMM]Life Sciences [q-bio]/Immunology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

28. The association between renal resistive index and premature mortality after kidney transplantation is modified by pre-transplant diabetes status: a cohort study

Author

de Freminville, Jean-Baptiste, primary, Vernier, Louis-Marie, additional, Roumy, Jérome, additional, Patat, Frédéric, additional, Gatault, Philippe, additional, Sautenet, Bénédicte, additional, Bailly, Elodie, additional, Chevallier, Eloi, additional, Barbet, Christelle, additional, Longuet, Hélène, additional, Merieau, Elodie, additional, Baron, Christophe, additional, Buchler, Matthias, additional, and Halimi, Jean-Michel, additional

Published
2019
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29. Increased risk of rejection after basiliximab induction in sensitized kidney transplant recipients without pre‐existing donor‐specific antibodies – a retrospective study

Author

Goumard, Annabelle, primary, Sautenet, Bénédicte, additional, Bailly, Elodie, additional, Miquelestorena‐Standley, Elodie, additional, Proust, Barbara, additional, Longuet, Hélène, additional, Binet, Lise, additional, Baron, Christophe, additional, Halimi, Jean‐Michel, additional, Büchler, Matthias, additional, and Gatault, Philippe, additional

Published
2019
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30. Impact on renal resistive index of diabetes in renal transplant donors and recipients: A retrospective analysis of 1827 kidney transplant recipients

Author

de Freminville, Jean‐Baptiste, primary, Vernier, Louis‐Marie, additional, Roumy, Jérome, additional, Patat, Frédéric, additional, Gatault, Philippe, additional, Sautenet, Bénédicte, additional, Bailly, Elodie, additional, Chevallier, Eloi, additional, Barbet, Christelle, additional, Longuet, Hélène, additional, Merieau, Elodie, additional, Baron, Christophe, additional, Buchler, Matthias, additional, and Halimi, Jean‐Michel, additional

Published
2019
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32. The association between renal resistive index and premature mortality after kidney transplantation is modified by pre-transplant diabetes status: a cohort study.

Author

Freminville, Jean-Baptiste de, Vernier, Louis-Marie, Roumy, Jérome, Patat, Frédéric, Gatault, Philippe, Sautenet, Bénédicte, Bailly, Elodie, Chevallier, Eloi, Barbet, Christelle, Longuet, Hélène, Merieau, Elodie, Baron, Christophe, Buchler, Matthias, and Halimi, Jean-Michel

Subjects
KIDNEY transplantation, EARLY death, PEOPLE with diabetes, COHORT analysis, DIABETES
Abstract

Background Renal resistive index (RI) predicts mortality in renal transplant recipients, but we do not know whether this is true in diabetic patients. The objective of this study was to analyse the long-term predictive value of RI for death with a functioning graft (DWFG) in renal transplant recipients with or without pre-transplant diabetes. Methods We conducted a retrospective study in 1800 renal transplant recipients between 1985 and 2017 who were followed for up to 30 years (total observation period: 14 202 patient years). Donor and recipient characteristics at time of transplantation and at 3 months were reviewed. The long-term predictive value of RI for DWFG and the age–RI and arterial pressure–RI relationships were assessed. Results A total of 284/1800 (15.7%) patients had diabetes mellitus before transplantation. RI was <0.75 in 1327/1800 patients (73.7%). High RI was associated with a higher risk of DWFG in non-diabetic patients [hazard ratio (HR) = 3.39, 95% confidence interval 2.50–4.61; P < 0.001], but not in patients with pre-transplant diabetes (HR = 1.25, 0.70–2.19; P = 0.39), even after multiple adjustments. There was no interaction between diabetes and age. In contrast, there was an interaction between RI and pulse pressure. Conclusion Our study indicates that RI is not a predictor of DWFG in diabetic renal transplant recipients, in contrast to non-diabetic recipients. These findings could be due to a different age–RI or pulse pressure–RI relationship. [ABSTRACT FROM AUTHOR]

Published
2020
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34. Polymorphism in programmed cell death 1 gene is strongly associated with lung and kidney allograft survival in recipients from CMV-positive donors

Author

Forconi, Catherine, primary, Gatault, Philippe, additional, Miquelestorena-Standley, Elodie, additional, Noble, Johan, additional, Al-Hajj, Sally, additional, Guillemain, Romain, additional, Stern, Marc, additional, Hoffmann, Thomas, additional, Prat, Louis, additional, Suberbielle, Caroline, additional, Masson, Emeline, additional, Cesbron-Gautier, Anne, additional, Gaudy-Graffin, Catherine, additional, Goudeau, Alain, additional, Thibault, Gilles, additional, Ivanes, Fabrice, additional, Guibon, Roseline, additional, Kazma, Ihab, additional, Lebranchu, Yvon, additional, Büchler, Matthias, additional, Magnan, Antoine, additional, Halimi, Jean-Michel, additional, and Baron, Christophe, additional

Published
2017
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35. Impact on renal resistive index of diabetes in renal transplant donors and recipients: A retrospective analysis of 1827 kidney transplant recipients.

Author

Freminville, Jean‐Baptiste, Vernier, Louis‐Marie, Roumy, Jérome, Patat, Frédéric, Gatault, Philippe, Sautenet, Bénédicte, Bailly, Elodie, Chevallier, Eloi, Barbet, Christelle, Longuet, Hélène, Merieau, Elodie, Baron, Christophe, Buchler, Matthias, Halimi, Jean‐Michel, de Freminville, Jean-Baptiste, Vernier, Louis-Marie, and Halimi, Jean-Michel

Abstract

High renal resistive index (RI) is observed in diabetes and is associated with poor patient survival, but whether it is primarily due to renal vascular resistance or systemic vascular alterations is unclear. The respective impact of kidney transplant from diabetic donors or to diabetic recipients on RI would shed some light on this issue. The objective of the study was to analyze the impact of donor and recipient diabetes on RI in order to understand the respective impact of the kidney and the vascular environment. The authors conducted a retrospective study in 1827 renal transplant recipients who received a kidney between 1985 and 2017, and had Doppler measurements at 3 months after transplant. Donor and recipient characteristics at the time of transplant and at 3 months were reviewed. Both donor diabetes and recipient diabetes were associated with RI in univariate analysis, but only recipient diabetes remained significantly associated in stepwise multivariate analyses (effect estimate on RI: +0.03 ± 0.005, P < 0.001). These findings were confirmed when RI was expressed as a binary variable using a cutoff of 0.75 (OR = 2.50 [1.77, 3.54], P < 0.001). Other determinants of RI were recipient characteristics (age, sex, systolic and diastolic blood pressure, and duration of dialysis). Donor characteristics were not associated with RI. Our results suggest that high RI observed in diabetic recipients shortly after transplant is primarily due to the new vascular environment, rather than to characteristics of the transplanted kidney. Therefore, RI reflects systemic rather than intra-renal changes. [ABSTRACT FROM AUTHOR]

Published
2019
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37. Explanations for the good behaviour in sewer networks of calcium aluminate cement materials

Author

Herisson, Jean, Gueguen Minerbe, Marielle, Van Hullebusch, Eric D., EYCHENNE-BARON, Christophe, Chaussadent, Thierry, Comportement Physico-chimique et Durabilité des Matériaux (IFSTTAR/MAST/CPDM), Communauté Université Paris-Est-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR), Laboratoire Géomatériaux et Environnement (LGE), Université Paris-Est Marne-la-Vallée (UPEM), Kerneos Research and Technology Center, Cadic, Ifsttar, and Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Communauté Université Paris-Est

Subjects
[CHIM.MATE] Chemical Sciences/Material chemistry, RESEAU D'ASSAINISSEMENT, CORROSION, [CHIM.MATE]Chemical Sciences/Material chemistry, [SPI.MAT] Engineering Sciences [physics]/Materials, [SPI.MAT]Engineering Sciences [physics]/Materials
Abstract

Sewer networks are subjected to many corrosion agents leading to deterioration of variant magnitude. One type of damage can be ascribed to concrete corrosion by biogenic sulfuric acid. According to field data, cementitious materials have different behaviours depending more especially on cement type. Those made with calcium aluminate cement (CAC) offer better performance than those made of ordinary Portland cement (OPC). This difference of durability may have three origins that can be combined. The first one is due to the oxidation of hydrogen sulfide at the surface of each materials leading to a lower amount of elemental sulfur deposited on CAC materials due to the difference of matrix composition (chemical composition and mineralogy). Elemental sulfur is then oxidized into sulfuric acid by microorganisms and leads to cementitious materials corrosion. The second one, the alumina content of CAC materials stabilizes the surface pH at around 3-4 and therefore limits the development of the most deleterious sulfur oxidizing bacteria. The last one, the aluminium content of CAC has a bacteriostatic effect on some microorganisms, limiting biofilm development. All that results are participating at the good performances of CAC materials.

Published
2013

38. Sulfur cycle in sewer networks and its consequences on cementitious materials

Author

Herisson, Jean, Van Hullebusch, Eric D., Gueguen, Marielle, Moletta-Denat, Marina, EYCHENNE-BARON, Christophe, Chaussadent, Thierry, Cadic, Ifsttar, Laboratoire Géomatériaux et Environnement (LGE), Université Paris-Est Marne-la-Vallée (UPEM), Département Matériaux (IFSTTAR/MAT), Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-PRES Université Paris-Est, Laboratoire de Biotechnologie de l'Environnement [Narbonne] (LBE), Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro)-Institut National de la Recherche Agronomique (INRA), Kerneos Research Technology Center, Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA), and Lge, Admin

Subjects
BETON, MICROORGANISME, ASSAINISSEMENT, BACTERIE, DEGRADATION, [SPI.MAT] Engineering Sciences [physics]/Materials, ALUMINATE, [SPI.MAT]Engineering Sciences [physics]/Materials
Abstract

Sewer networks enclose many biological and chemical transformations involving sulfur molecules oxidation leading to biogenic sulfuric acid production. Sewage effluents contain many sulfur species such as sulfates and sulfites which are reduced in anoxic zones by sulfate reducing bacteria (Desulfovibrio sp., Desulfobulbus sp.) into hydrogen sulfide (H2S). This gas is emitted in the aerial part of the pipe and degrades materials. This deterioration proceeds either directly as H2S is a corrosive gas, or indirectly through the action of microorganisms that will oxidize H2S into sulfuric acid. This acid will dissolve the cement matrix and produce expansive products (such as gypsum or ettringite). In the worst case it leads to pipes destruction. This study aims at understanding the deterioration mechanisms occuring in the aerial part of the pipe. A special attention is given to the impact of different cementitious material on microorganisms involved in the global sulfur cycle (sulfur oxidizing bacteria such as Starkeya novella, Halothiobacillus neapolitanus, Thiomonas intermedia and Acidithiobacillus thiooxidans). According to field data, cementitious materials made with Calcium Aluminate Cement (CAC) offer far better performance on site than those made of Ordinary Portland Cement (OPC). This behaviour difference is likely associated with a different microorganism diversity. This work is divided into three parts. The first one consists in an exposition of CAC and OPC mortars in real sewer networks. This on-site experiment aims to follow the evolution of biodiversity and also to characterize the degradation of cementitious materials. Capillary Electrophoresis - Single Strand Conformation Polymorphism (CE-SSCP) analyses performed on each sample reveals that biodiversity is highly related to cement composition. OPC mortars hosts more numerous and diverse microorganisms than CAC mortars. The second part is represented by various lab experiments aiming to better describe the different steps involved in the whole mechanism. According to our tests, abiotic oxidation of H2S into elemental sulfur is highly dependent on materials composition. While elemental sulfur deposition can be seen on OPC mortars, none is observed on CAC mortars. Depending on sulfur source available, bacteria will have various growth rates. We have studied the impact of three sulfur sources (S2O32-, S0, H2S) on the growth of sulfur oxidising bacteria. All results obtained are used, in a third part, to design an accelerated experiment that should be standardized to test sewer networks materials.

Published
2012

39. Hemolytic Uremic Syndrome: Recurrence after Renal Transplantation

Author

LAHLOU, ANIS, LANG, PHILIPPE, CHARPENTIER, BERNARD, BARROU, BENOIT, GLOTZ, DENIS, BARON, CHRISTOPHE, HIESSE, CHRISTIAN, KREIS, HENRI, LEGENDRE, CHRISTOPHE, BEDROSSIAN, JEANINE, MOUGENOT, BEATRICE, SRAER, JEAN DANIEL, and RONDEAU, ERIC

Subjects
Hemolytic-uremic syndrome -- Care and treatment, Kidneys -- Transplantation
Published
2000

41. SP007GENOME-WIDE ASSOCIATION STUDY IDENTIFIES NEW LOCI ASSOCIATED WITH ACUTE RENAL GRAFT REJECTION

Author

Ghisdal, Lidia, primary, Baron, Christophe, additional, Lebranchu, Yvon, additional, Viklický, Ondrej, additional, Konarikova, Alena, additional, Naesen, Maerten, additional, Dinic, Miriana, additional, Alamartine, Eric, additional, Touchard, Guy, additional, Thierry, Antoine, additional, Essig, Marie, additional, Rerolle, Jean-Philippe, additional, Merville, Pierre, additional, Taupin, Jean-Luc, additional, Le Meur, Yannick, additional, Glowacki, François, additional, Noël, Christian, additional, Legendre, Christophe, additional, Coppieter, Wouter, additional, Do Campo, Elisa, additional, Georges, Michel, additional, Massart, Annick, additional, Racapé, Judith, additional, Abramowicz, Daniel, additional, and Abramowicz, Marc, additional

Published
2015
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42. TCF7L2 POLYMORPHISM IS AN INDEPENDENT RISK FACTOR FOR NEW ONSET DIABETES MELLITUS AFTER TRANSPLANTATION: A COHORT STUDY ON 1229 RENAL TRANSPLANT PATIENTS

Author

Ghisdal, Lidia, Baron, Christophe, Lebranchu, Yvon, Halimi, Jean-Michel, Le Meur, Yannick, Rerolle, Jean-Philippe, Drouet, Mireille, Lionet, Arnaud, Glowacki, Francois, Noel, Christian, Wissing, Karl Martin, Abramowicz, Daniel, Abramowicz, Marc, and Internal Medicine Specializations

Subjects
TCF7L2, diabetes mellitus, new onset, Risk factor, polymorphism
Abstract

No abstract available

Published
2009

45. CMV‐infected kidney grafts drive the expansion of blood‐borne CMV‐specific T cells restricted by shared class I HLAmolecules via presentation on donor cells

Author

Gatault, Philippe, Al‐Hajj, Sally, Noble, Johan, Chevallier, Eloi, Piollet, Marie, Forconi, Catherine, Gaudy‐Graffin, Catherine, Thibault, Gilles, Miquelestorena‐Standley, Elodie, Halimi, Jean‐Michel, Büchler, Matthias, Lemoine, Roxane, and Baron, Christophe

Abstract

We aimed to determine the role of cytomegalovirus (CMV)‐infected donor cells in the development of a CMV‐specific immune response in kidney transplant recipients. We assessed the CMVpp65‐specific immune response by using interferon‐ɣ ELISPOTand dextramers in peripheral blood mononuclear cells from 115 recipients (D+R− 31, D+R + 44, D−R + 40) late after transplantation (mean 59 ± 42 months). Receiving a kidney from a D+ donor resulted in a higher number of IFN‐ɣ‐producing anti‐CMVT cells (P= .004). This effect disappeared with the absence of shared HLAclass I specificities between donors and recipients (P= .430). To confirm the role of donor cells in stimulating the expansion of newly developed CMV‐specific CD8+T cells after transplantation, we compared the number of HLA‐A2–restricted CMV‐specific CD8+T cells in primo‐infected recipients who received an HLA‐A2 or non–HLA‐A2 graft. The median of anti‐CMVpp65 T cells restricted by HLA‐A2 was very low for patients who received a non–HLA‐A2 graft vs an HLA‐A2 graft (300 [0‐14638] vs. 17972 [222‐85594] anti‐CMVpp65 CD8+T cells/million CD8+T cells, P= .001). This adds new evidence that CMV‐infected kidney donor cells present CMVpeptides and drive an inflation of memory CMV‐specific CD8+T cells, likely because of frequent CMVreplications within the graft. Donor cytomegalovirus (CMV) infection affects the CMV‐specific immune response and donor‐shared HLA‐I is crucial for the development of CMV‐specific CD8+ T cells, suggesting that CMV‐infected kidney donor cells present CMV peptides and drive an inflation in memory CMV‐specific T cells.

Published
2018
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46. Risk factors for impairedCD4+T‐cell reconstitution following rabbit antithymocyte globulin treatment in kidney transplantation

Author

Longuet, Hélène, primary, Sautenet, Bénédicte, additional, Gatault, Philippe, additional, Thibault, Gilles, additional, Barbet, Christelle, additional, Marliere, Jean‐Frédérique, additional, Halimi, Jean‐Michel, additional, Lebranchu, Yvon, additional, Baron, Christophe, additional, and Büchler, Matthias, additional

Published
2013
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48. Reaction of Butyltin Hydroxide Oxide with p -Toluenesulfonic Acid: Synthesis, X-ray Crystal Analysis, and Multinuclear NMR Characterization of {(BuSn)12O14(OH)6}(4-CH3C6H4SO3)2

Author

EYCHENNE-BARON, Christophe, Ribot, François, Steunou, Nathalie, Sanchez, Clément, Fayon, Franck, Biesemans, Monique, Martins, José, Willem, Rudolph, Laboratoire de Chimie de la Matière Condensée de Paris (site Paris VI) (LCMCP (site Paris VI)), Université Pierre et Marie Curie - Paris 6 (UPMC)-Collège de France (CdF (institution))-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Matériaux Hybrides et Nanomatériaux (LCMCP-MHN), Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Novel Advanced Nano-Objects (LCMCP-NANO), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre de recherches sur les matériaux à haute température (CRMHT), Centre National de la Recherche Scientifique (CNRS), High-Resolution NMR Centre, Vrije Universiteit Brussel (VUB), High Resolution NMR Centre, and Vrije Universiteit Brussel

Subjects
[CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.INOR]Chemical Sciences/Inorganic chemistry, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2000

49. Pharmacokinetic and pharmacodynamic studies of two different rabbit antithymocyte globulin dosing regimens: Results of a randomized trial

Author

Büchler, Matthias, primary, Longuet, Hélène, additional, Lemoine, Roxane, additional, Herr, Florence, additional, Gatault, Philippe, additional, Thibault, Gilles, additional, Ternant, David, additional, Foulon, Christine, additional, Pilorge, Bernadette, additional, Lemay, Djamila, additional, Sung, Crystal, additional, Halimi, Jean-Michel, additional, Baron, Christophe, additional, and Lebranchu, Yvon, additional

Published
2013
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