Search

Background: The advent of Deep Learning initiated a new era in which neural networks relying solely on Whole-Slide Images can estimate the survival time of cancer patients. Remarkably, despite deep learning's potential in this domain, no prior research has been conducted on image-based survival analysis specifically for peritoneal mesothelioma. Prior studies performed statistical analysis to identify disease factors impacting patients' survival time. Methods: Therefore, we introduce MPeMSupervisedSurv, a Convolutional Neural Network designed to predict the survival time of patients diagnosed with this disease. We subsequently perform patient stratification based on factors such as their Peritoneal Cancer Index and on whether patients received chemotherapy treatment. Results: MPeMSupervisedSurv demonstrates improvements over comparable methods. Using our proposed model, we performed patient stratification to assess the impact of clinical variables on survival time. Notably, the inclusion of information regarding adjuvant chemotherapy significantly enhances the model's predictive prowess. Conversely, repeating the process for other factors did not yield significant performance improvements. Conclusions: Overall, MPeMSupervisedSurv is an effective neural network which can predict the survival time of peritoneal mesothelioma patients. Our findings also indicate that treatment by adjuvant chemotherapy could be a factor affecting survival time. [ABSTRACT FROM AUTHOR]

In the current context of climate change and demographic expansion, one of the phenomena that humanity faces are the suburban wildfires. To prevent the occurrence of suburban forest fires, fire risk assessment and early fire detection approaches need to be applied. Forest fire risk mapping depends on various factors and contributes to the identification and monitoring of vulnerable zones where risk factors are most severe. Therefore, watchtowers, sensors, and base stations of autonomous unmanned aerial vehicles need to be placed carefully in order to ensure adequate visibility or battery autonomy. In this study, fire risk assessment of an urban forest was performed and the recently introduced 360-degree data were used for early fire detection. Furthermore, a single-step approach that integrates a multiscale vision transformer was introduced for accurate fire detection. The study area includes the suburban pine forest of Thessaloniki city (Greece) named Seich Sou, which is prone to wildfires. For the evaluation of the performance of the proposed workflow, real and synthetic 360-degree images were used. Experimental results demonstrate the great potential of the proposed system, which achieved an F-score for real fire event detection rate equal to 91.6%. This indicates that the proposed method could significantly contribute to the monitoring, protection, and early fire detection of the suburban forest of Thessaloniki. [ABSTRACT FROM AUTHOR]

Gastric cancer is one of the most frequent causes of cancer-related deaths worldwide. Gastric atrophy (GA) and gastric intestinal metaplasia (IM) of the mucosa of the stomach have been found to increase the risk of gastric cancer and are considered precancerous lesions. Therefore, the early detection of GA and IM may have a valuable role in histopathological risk assessment. However, GA and IM are difficult to confirm endoscopically and, following the Sydney protocol, their diagnosis depends on the analysis of glandular morphology and on the identification of at least one well-defined goblet cell in a set of hematoxylin and eosin (H&E) -stained biopsy samples. To this end, the precise segmentation and classification of glands from the histological images plays an important role in the diagnostic confirmation of GA and IM. In this paper, we propose a digital pathology end-to-end workflow for gastric gland segmentation and classification for the analysis of gastric tissues. The proposed GAGL-VTNet, initially, extracts both global and local features combining multi-scale feature maps for the segmentation of glands and, subsequently, it adopts a vision transformer that exploits the visual dependences of the segmented glands towards their classification. For the analysis of gastric tissues, segmentation of mucosa is performed through an unsupervised model combining energy minimization and a U-Net model. Then, features of the segmented glands and mucosa are extracted and analyzed. To evaluate the efficiency of the proposed methodology we created the GAGL dataset consisting of 85 WSI, collected from 20 patients. The results demonstrate the existence of significant differences of the extracted features between normal, GA and IM cases. The proposed approach for gland and mucosa segmentation achieves an object dice score equal to 0.908 and 0.967 respectively, while for the classification of glands it achieves an F1 score equal to 0.94 showing great potential for the automated quantification and analysis of gastric biopsies. [ABSTRACT FROM AUTHOR]

Pedestrian detection is a challenging task, mainly owing to the numerous appearances of human bodies. Modern detectors extract representative features via the deep neural network; however, they usually require a large training set and high-performance GPUs. For these cases, we propose a novel human detection approach that integrates a pretrained face detector based on multitask cascaded convolutional neural networks and a traditional pedestrian detector based on aggregate channel features via a score combination module. The proposed detector is a promising approach that can be used to handle pedestrian detection with limited datasets and computational resources. The proposed detector is investigated comprehensively in terms of parameter choices to optimize its performance. The robustness of the proposed detector in terms of the training set, test set, and threshold is observed via tests and cross dataset validations on various pedestrian datasets, including the INRIA, part of the ETHZ, and the Caltech and Citypersons datasets. Experiments have proved that this integrated detector yields a significant increase in recall and a decrease in the log average miss rate compared with sole use of the traditional pedestrian detector. At the same time, the proposed method achieves a comparable performance to FRCNN on the INRIA test set compared with sole use of the Aggregated Channel Features detector. [ABSTRACT FROM AUTHOR]

Tertiary lymphoid structures (TLS) are ectopic aggregates of lymphoid cells in inflamed, infected, or tumoral tissues that are easily recognized on an H&E histology slide as discrete entities, distinct from lymphocytes. TLS are associated with improved cancer prognosis but there is no standardised method available to quantify their presence. Previous studies have used immunohistochemistry to determine the presence of specific cells as a marker of the TLS. This has now been proven to be an underestimate of the true number of TLS. Thus, we propose a methodology for the automated identification and quantification of TLS, based on H&E slides. We subsequently determined the mathematical criteria defining a TLS. TLS regions were identified through a deep convolutional neural network and segmentation of lymphocytes was performed through an ellipsoidal model. This methodology had a 92.87% specificity at 95% sensitivity, 88.79% specificity at 98% sensitivity and 84.32% specificity at 99% sensitivity level based on 144 TLS annotated H&E slides implying that the automated approach was able to reproduce the histopathologists' assessment with great accuracy. We showed that the minimum number of lymphocytes within TLS is 45 and the minimum TLS area is 6,245μm2. Furthermore, we have shown that the density of the lymphocytes is more than 3 times those outside of the TLS. The mean density and standard deviation of lymphocytes within a TLS area are 0.0128/μm2 and 0.0026/μm2 respectively compared to 0.004/μm2 and 0.001/μm2 in non-TLS regions. The proposed methodology shows great potential for automated identification and quantification of the TLS density on digital H&E slides. [ABSTRACT FROM AUTHOR]

The recognition of wood species is a laborious process, which is performed by experts, who attempt to distinguish the different species in different wood sections based on their macroscopic and microscopic characteristics. Most of these characteristics can be observed in the transverse or cross section of woods. According to experts, the next most important surface for wood species recognition is the tangential section while significant information can also be obtained from the radial section of woods. Based on the recent advances in the area of computer vision and pattern recognition, most researchers have proposed imagebased approaches attempting to address the problem either in microscopic or macroscopic scale. The main limitation is that in many cases there are some features that are not visible in each wood section. Firstly, we examine the contribution of each section in wood species recognition using two different computer-based texture analysis methods. Furthermore, we compare wood species recognition methods for both grayscale images and colorscale images. Finally, we propose a novel fusion method and we demonstrate that wood species recognition accuracy can be increased by fusing features from different wood sections. For the evaluation of the proposed method, a dataset, namely "WOOD-AUTH", consisting of more than 4272 wood images of twelve common wood species, was used. [ABSTRACT FROM AUTHOR]

In this paper we address the problem of automated grading of invasive breast carcinoma through the encoding of histological images as VLAD (Vector of Locally Aggregated Descriptors) representations on the Grassmann manifold. The proposed method considers each image as a set of multidimensional spatially-evolving signals that can be efficiently modeled through a higher-order linear dynamical systems analysis. Subsequently, each H&E (Hematoxylin and Eosin) stained breast cancer histological image is represented as a cloud of points on the Grassmann manifold, while a vector representation approach is applied aiming to aggregate the Grassmannian points based on a locality criterion on the manifold. To evaluate the efficiency of the proposed methodology, two datasets with different characteristics were used. More specifically, we created a new medium-sized dataset consisting of 300 annotated images (collected from 21 patients) of grades 1, 2 and 3, while we also provide experimental results using a large dataset, namely BreaKHis, containing 7,909 breast cancer histological images, collected from 82 patients, of both benign and malignant cases. Experimental results have shown that the proposed method outperforms a number of state of the art approaches providing average classification rates of 95.8% and 91.38% with our dataset and the BreaKHis dataset, respectively. [ABSTRACT FROM AUTHOR]

In this paper, we consider the problem of multi-dimensional dynamic texture analysis, and we introduce a new higher order linear dynamical system (h-LDS) descriptor. The proposed h-LDS descriptor is based on the higher order decomposition of the multidimensional image data and enables the analysis of dynamic textures by using information from various image elements. In addition, we propose a methodology for its application to video-based early warning systems that focus on smoke identification. More specifically, the proposed methodology enables the representation of video subsequences as histograms of h-LDS descriptors produced by the smoke candidate image patches in each subsequence. Finally, to further improve the classification accuracy, we propose the combination of multidimensional dynamic texture analysis with the spatiotemporal modeling of smoke by using a particle swarm optimization approach. The ability of the h-LDS to analyze the dynamic texture information is evaluated through a multivariate comparison against the standard LDS descriptor. The experimental results that use two video datasets have shown the great potential of the proposed smoke detection method. [ABSTRACT FROM PUBLISHER]

Forest biomass originating from Mediterranean forest vegetation could be a potential source of renewable energy in the form of pellets, butdue to its diversity there is a need for better understanding and detailed examination of its main fuel characteristics. The aim of this work was the evaluation of the impact that bark percentage and barked stem diameter have on the ash content and heating value of thefollowing evergreen Mediterranean hardwood species: Arbutus unedo, Erica arborea, Quercus coccifera, Quercus ilex and Phillyrea latifolia. For all the above species, the barked diameter, bark thickness, bark percentage as well as the ash content and higher heating value of bark and wood have been determined. In all cases the ash content of bark was higher than that of wood and also higher than the requirement of the related EN standard. Therefore the bark of tested species could be used in the production of pellets provided that its ratio would be in a level corresponding to the maximum allowed ash content values. Taking into account the results of the determinations, the equations and graphs were used in order to calculate the minimum of the stem diameter requirements in order to meet with the ash content restrictions. The effect of stem diameter on the HHV (higher heating value) was also evaluated. Among the tested species, Erica arborea proved to be the most appropriate for the production of pellets showing the highest HHV and the lowest ash content. [ABSTRACT FROM AUTHOR]

In this study, Scots pine wood (Pinus sylvestris L.) was thermally treated at 200oC, for three different time periods of 4, 6 and 8 hours. The Bending strength (MOR) and Impact Bending strength of treated and untreated pine wood specimens were determined and measurements of wood colour were implemented before and after each thermal treatment, in order to evaluate the colour changes coming from the treatment processes. An attempt was made to correlate this colour change with the change of the mechanical properties of treated wood. The results indicated that MOR decreased as the intensity of the treatment increased, recording decrease percentages of between 0.34-25.9%, compared to untreated wood, while the impact bending strength values of treated specimens marked 0.69-22.34% lower strength. The noteworthy is that a strong and significant relationship was recorded between the colour change and the mechanical properties change. Based on the results of this study, it could be claimed that the mechanical strength values of treated pinewood could be sufficiently estimated by the corresponding colour change values that have been measured. Therefore, the measurement of colour coordinates and the calculation of the total colour change values offer the opportunity to estimate automatically, quite precisely and through a non-destructive way the mechanical properties of wood. [ABSTRACT FROM AUTHOR]

Every year, a large number of wildfires all over the world burn forested lands, causing adverse ecological, economic, and social impacts. Beyond taking precautionary measures, early warning and immediate response are the only ways to avoid great losses. To this end, in this paper we propose a computer vision approach for fire-flame detection to be used by an early-warning fire monitoring system. Initially, candidate fire regions in a frame are defined using background subtraction and color analysis based on a nonparametric model. Subsequently, the fire behavior is modeled by employing various spatio-temporal features, such as color probability, flickering, spatial, and spatio-temporal energy, while dynamic texture analysis is applied in each candidate region using linear dynamical systems and a bag-of-systems approach. To increase the robustness of the algorithm, the spatio-temporal consistency energy of each candidate fire region is estimated by exploiting prior knowledge about the possible existence of fire in neighboring blocks from the current and previous video frames. As a final step, a two-class support vector machine classifier is used to classify the candidate regions. Experimental results have shown that the proposed method outperforms existing state-of-the-art algorithms. [ABSTRACT FROM PUBLISHER]

The environmental challenges the world faces nowadays have never been greater or more complex. Global areas covered by forests and urban woodlands are threatened by natural disasters that have increased dramatically during the last decades, in terms of both frequency and magnitude. Large-scale forest fires are one of the most harmful natural hazards affecting climate change and life around the world. Thus, to minimize their impacts on people and nature, the adoption of well-planned and closely coordinated effective prevention, early warning, and response approaches are necessary. This paper presents an overview of the optical remote sensing technologies used in early fire warning systems and provides an extensive survey on both flame and smoke detection algorithms employed by each technology. Three types of systems are identified, namely terrestrial, airborne, and spaceborne-based systems, while various models aiming to detect fire occurrences with high accuracy in challenging environments are studied. Finally, the strengths and weaknesses of fire detection systems based on optical remote sensing are discussed aiming to contribute to future research projects for the development of early warning fire systems. [ABSTRACT FROM AUTHOR]

The environmental challenges the world faces have never been greater or more complex. Global areas that are covered by forests and urban woodlands are threatened by large-scale forest fires that have increased dramatically during the last decades in Europe and worldwide, in terms of both frequency and magnitude. To this end, rapid advances in remote sensing systems including ground-based, unmanned aerial vehicle-based and satellite-based systems have been adopted for effective forest fire surveillance. In this paper, the recently introduced 360-degree sensor cameras are proposed for early fire detection, making it possible to obtain unlimited field of view captures which reduce the number of required sensors and the computational cost and make the systems more efficient. More specifically, once optical 360-degree raw data are obtained using an RGB 360-degree camera mounted on an unmanned aerial vehicle, we convert the equirectangular projection format images to stereographic images. Then, two DeepLab V3+ networks are applied to perform flame and smoke segmentation, respectively. Subsequently, a novel post-validation adaptive method is proposed exploiting the environmental appearance of each test image and reducing the false-positive rates. For evaluating the performance of the proposed system, a dataset, namely the "Fire detection 360-degree dataset", consisting of 150 unlimited field of view images that contain both synthetic and real fire, was created. Experimental results demonstrate the great potential of the proposed system, which has achieved an F-score fire detection rate equal to 94.6%, hence reducing the number of required sensors. This indicates that the proposed method could significantly contribute to early fire detection. [ABSTRACT FROM AUTHOR]

Wood recognition is a crucial task for wood sciences and industries, since it leads to the identification of the anatomical features and physical properties of wood. Traditionally, the recognition process relies almost exclusively on human experts, who are based on various characteristics of wood, such as color, structure and texture. However, there are numerous types of wood species in the nature that are difficult to be identified even by experienced scientists. Towards this end, in this paper we propose a novel approach for automated wood species recognition through multidimensional texture analysis. By taking advantage of the fact that static wood images contain periodic spatially-evolving characteristics, we introduce a new spatial descriptor considering each wood image as a collection of multidimensional signals. More specifically, the proposed methodology enables the representation of wood images as concatenated histograms of higher order linear dynamical systems produced by vertical and horizontal image patches. The final classification of images, i.e., histogram representations, into wood species, is performed using a Support Vector Machines (SVM) classifier. For the evaluation of the proposed method, a dataset, namely “WOOD-AUTH”, consisting of more than 4200 wood images (from cross, radial and tangential sections of normal wood structure) of twelve common wood species existing in Greek territory, was created. Experimental results presented in this paper show the great potential of the proposed methodology, which, despite a small number of misclassification cases with regards to both anatomically similar and different species, outperforms a number of state of the art approaches, yielding a classification rate of 91.47% in wood cross sections. [ABSTRACT FROM AUTHOR]