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10 results on '"Bargalló-Alabart N"'

8. [Epilepsy surgery in a reference centre]

Author

Elices E, Rumiá J, Cañizares-Alejos S, Boget-Llucià T, Setoáin-Perego J, Pintor-Pérez L, Bargalló-Alabart N, Teresa Ribalta Farres, and Arroyo S

Subjects
Adult, Male, Epilepsy, Adolescent, Humans, Female, Middle Aged, Anterior Temporal Lobectomy, Referral and Consultation
Abstract

Patients with drug resistant epilepsy are potential candidates for surgery. The pre surgical study of these patients involves a multidisciplinary approach.We included patients who had been submitted to EEG video monitoring in our centre (a tertiary university hospital) between April 1995 and May 2000. The evaluation protocol included magnetic resonance (MR) brain scan (according to a specific protocol), neuropsychological and psychiatric evaluation, and ictal/interictal SPECT, when possible. Patients who underwent surgery were followed up at regular intervals until at least two years after surgery.Of the 299 patients with EEG video monitoring, 87 had been submitted to surgery up to June 2000. Nine of these patients required invasive subdural studies or studies of the foramen ovale using electrodes. Of the patients who underwent surgery, 44.8% had sclerosis of the hippocampus in the MR and in 10% it was found to be normal. The results of pathological anatomy revealed: 49.3% with sclerosis of the hippocampus, 15.1% with benign tumours, 13.7% with gliosis, 4.1% heterotopias and 4.1% cavernomas. Just one patient has been submitted to surgery again because of badly controlled seizures. Eight patients have presented post surgical complications (four with permanent morbidity). Of the 73 patients who were followed up for at least a year, 83.6% are in Engel class I, 9.6% in class II, 2.7% in class III and 4.1% in class IV. Among patients who underwent a temporal resection, 88.7% were in class I and 0% in class IV.Epilepsy surgery, in selected patients, has a very low morbidity/mortality rate and the chances that seizures will disappear or greatly improve are high.

Published
2002

10. [Neuroimaging and cerebral palsy].

Author

Pueyo-Benito R, Vendrell-Gómez P, Bargalló-Alabart N, and Mercader-Sobrequés JM

Subjects
Diagnostic Imaging, Humans, Cerebral Palsy pathology
Abstract

Introduction: A high percentage of subjects with cerebral palsy (CP) present brain injuries, which are revealed by neuroimaging techniques. On the whole the pattern of brain damage is heterogeneous., Development: We review the studies that have described the brain damage in CP using structural and functional neuroimaging techniques. Brain damage is considered according to the type of CP and taking the gestational age into account., Conclusions: According to structural neuroimaging studies carried out in spastic diplegia, the brain pattern differs with the gestational age. In early subjects with spastic diplegia it is the periventricular white matter that is mainly affected. In spastic quadriplegia, cortico subcortical lesions and hypoplasia of the corpus callosum are also observed. Unilateral lesions predominate in the case of hemiplegia. Hemiplegic subjects may also present damage to the white matter, cortico subcortical lesions and congenital brain malformations. In these subjects, some of the injury patterns observed seem to be related with the clinical features they display. Dyskinetic CP is characterised by the absence of lesions and alteration of the basal ganglia and the thalamus. Very few studies have been conducted that take the different types of CP into account in comparing the findings of structural and functional neuroimaging.

Published
2002

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