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2. Clinical characteristics of bipolar disorders with postpartum depressive onset

Author

Etain, B., Henry, C., Olié, E., Leboyer, M., Haffen, E., Llorca, P.M., Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Drancourt, N., Sanchez, J.P., Saliou, E., Hebbache, C., Petrucci, J., Willaume, L., Bourdin, E., Bellivier, F., Carminati, M., Marlinge, E., Meheust, J., Antoniol, B., Desage, A., Gard, S., Jutant, A., Mbailara, K., Minois, I., Zanouy, L., Abettan, C., Bardin, L., Cazals, A., Courtet, P., Deffinis, B., Ducasse, D., Gachet, M., Henrion, A., Martinerie, E., Molière, F., Noisette, B., Tarquini, G., Azorin, J.M., Belzeaux, R., Correard, N., Consoloni, J.L., Groppi, F., Lescalier, L., Montant, J., Rebattu, M., Viglianese, N., Cohen, R., Kahn, J.P., Milazzo, M., Wajsbrot-Elgrabli, O., Bougerol, T., Fredembach, B., Suisse, A., Halili, B., Pouchon, A., Polosan, M., Galliot, A.M., Grévin, I., Cannavo, A.S., Kayser, N., Passerieux, C., Roux, P., Aubin, V., Cussac, I., Dupont, M.A., Loftus, J., Medecin, I., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., Tebeka, Sarah, Godin, Ophelia, Mazer, Nicolas, Bellivier, Frank, Courtet, Philippe, Etain, Bruno, Gard, Sébastien, Leboyer, Marion, Llorca, Pierre-Michel, Loftus, Joséphine, Olié, Emilie, Passerieux, Christine, Polosan, Mircea, Schwan, Raymund, Belzeaux, Raoul, and Dubertret, Caroline

Published
2021
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3. Clinical predictors of recurrences in bipolar disorders type 1 and 2: A FACE-BD longitudinal study

Author

Etain, B., Olié, E., Leboyer, M., Llorca, P.M., Henry, C., Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Sanchez, J.P., Saliou, E., Hebbache, C., Petrucci, J., Willaume, L., Bourdin, E., Bellivier, F., Carminati, M., Maruani, J., Marlinge, E., Meheust, J., Antoniol, B., Desage, A., Gard, S., Jutant, A., Mbailara, K., Minois, I., Zanouy, L., Abettan, C., Bardin, L., Cazals, A., Courtet, P., Deffinis, B., Ducasse, D., Gachet, M., Henrion, A., Martinerie, E., Molière, F., Noisette, B., Tarquini, G., Azorin, J.M., Belzeaux, R., Correard, N., Consoloni, J.L., Groppi, F., Lescalier, L., Montant, J., Rebattu, M., Viglianese, N., Cohen, R., Gross, G., Schwan, R., Schwitzer, T., Wajsbrot-Elgrabli, O., Bougerol, T., Fredembach, B., Suisse, A., Halili, B., Gaoua, Z., Polosan, M., Cannavo, A.S., Galliot, A.M., Grévin, I., Kayser, N., Liaskovski, G., Passerieux, C., Roux, P., Aubin, V., Cussac, I., Dupont, M.A., Loftus, J., Medecin, I., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., and Aouizerate, B.

Published
2021
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7. Key findings on bipolar disorders from the longitudinal FondaMental Advanced Center of Expertise-Bipolar Disorder (FACE-BD) cohort

Author

Leboyer, M., primary, Godin, O., additional, Llorca, P.M., additional, Aubin, V., additional, Bellivier, F., additional, Belzeaux, R., additional, Courtet, P., additional, Costagliola, D., additional, Dubertret, C., additional, M'Bailara, K., additional, Haffen, E., additional, Henry, C., additional, Laouamri, H., additional, Passerieux, C., additional, Pelletier, A., additional, Polosan, M., additional, Roux, P., additional, Schwan, R., additional, Samalin, L., additional, Olié, E., additional, Etain, Bruno, additional, Etain, B., additional, Leboyer, M., additional, Barteau, V., additional, Bensalem, S., additional, Souryis, K., additional, Hotier, S., additional, Sanchez, J.P., additional, Saliou, E., additional, Hebbache, C., additional, Petrucci, J., additional, Wuillaume, L., additional, Bourdin, E., additional, Carminati, M., additional, Hennion, V., additional, Marlinge, E., additional, Meheust, J., additional, Zekri, C., additional, Desage, A., additional, Gard, S., additional, Minois, I., additional, Sportich, J., additional, Zanouy, L., additional, Abettan, C., additional, Bardin, L., additional, Cazals, A., additional, Deffinis, B., additional, Ducasse, D., additional, Gachet, M., additional, Henrion, A., additional, Martinerie, E., additional, Molière, F., additional, Noisette, B., additional, and Tarquini, E.G., additional

Published
2022
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8. Childhood maltreatment and metabolic syndrome in bipolar disorders: In search of moderators

Author

Etain, B., Henry, C., Olié, E., Leboyer, M., Haffen, E., Llorca, PM, Barteau, V., Bensalem, S., Godin, O., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Drancourt, N., Sanchez, JP., Saliou, E., Hebbache, C., Petrucci, J., Willaume, L., Bourdin, E., Bellivier, F., Carminati, M., Marlinge, E., Meheust, J., Meyrel, M., Aouizerate, B., Desage, A., Gard, S., Sportich, J, Mbailara, K., Minois, I., Zanouy, L., Bardin, L., Cazals, A., Courtet, P., Deffinis, B., Ducasse, D., Gachet, M., Henrion, A., Moliere, F., Noisette, B., Olie, E., Tarquini, G., Belzeaux, R., Correard, N., Groppi, F., Lefrere, A., Lescalier, L., Moreau, E., Pastol, J., Rebattu, M., Roux, B., Viglianese, N., Cohen, R., Schwan, Raymond, Kahn, J.P., Milazzo, M., Wajsbrot-Elgrabli, O., Bougerol, T., Fredembach, B., Suisse, A., Halili, B., Pouchon, A, Polosan, M., Galliot, A.M., Grévin, I., Cannavo, A.S., Kayser, N., Passerieux, C., Roux, P., Service de Psychiatrie, Aubin, V., Cussac, I., Dupont, M.A, Loftus, J., Medecin, I., Dubertret, C., Mazer, N., Portalier, C., Scognamiglio, C., Bing, A., Godin, Ophelia, Gaube, Géraud, Olié, Emilie, Belzeaux, Raoul, Bellivier, Frank, Loftus, Joséphine, Courtet, Philippe, Dubertret, Caroline, llorca, Pierre-Michel, Gard, Sebastien, Henry, Chantal, Schwan, Raymund, Passerieux, Christine, Polosan, Mircea, Samalin, Ludovic, Leboyer, Marion, and Etain, Bruno

Published
2021
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9. Handedness in bipolar disorders is associated with specific neurodevelopmental features: results of the BD-FACE cohort

Author

Mallet, Jasmina, Godin, Ophélia, Mazer, Nicolas, Le Strat, Yann, Bellivier, Frank, Belzeaux, Raoul, Etain, Bruno, Fond, Guillaume, Gard, Sébastien, Henry, Chantal, Leboyer, Marion, Llorca, Pierre-Michel, Loftus, Joséphine, Olié, Emilie, Passerieux, Christine, Polosan, Mircea, Schwan, Raymund, Roux, Paul, Dubertret, Caroline, Barteau, V., Bensalem, S., Laouamri, H., Souryis, K., Hotier, S., Pelletier, A., Drancourt, N., Sanchez, J., Saliou, E., Hebbache, C., Petrucci, J., Willaume, L., Bourdin, E., Carminati, M., Marlinge, E., Meheust, J., Antoniol, B., Desage, A., Jutant, A., Mbailara, K., Minois, I., Zanouy, L., Abettan, C., Bardin, L., Cazals, A., Courtet, P., Deffinis, B., Ducasse, D., Gachet, M., Henrion, A., Martinerie, E., Molière, F., Noisette, B., Tarquini, G., Azorin, J., Correard, N., Muraccioli, I., Groppi, F., Lescalier, L., Rebattu, M., Viglianese, N., Cohen, R., Kahn, J., Milazzo, M., Wajsbrot-Elgrabli, O., Bougerol, T., Fredembach, B., Suisse, A., Tassan, L., Pouchon, A., Cannavo, A., Crea, A., Feuga, V., Galliot, A., Kayser, N., Aubin, V., Cussac, I., Dupont, M., Medecin, I., Bing, A., Samalin, L., Foures, L, Lacelle, D., Pires, S., Doriat, C., Blanc, O., Fondation FondaMental [Créteil], Hôpital Louis Mourier - AP-HP [Colombes], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), IMRB - 'Biologie du système neuromusculaire' [Créteil] (U955 Inserm - UPEC), École nationale vétérinaire - Alfort (ENVA)-Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Optimisation thérapeutique en Neuropsychopharmacologie (OPTeN (UMR_S_1144 / U1144)), Assistance Publique - Hôpitaux de Marseille (APHM), Institut de Neurosciences de la Timone (INT), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre d'études et de recherche sur les services de santé et la qualité de vie (CEReSS), Aix Marseille Université (AMU), CHU Bordeaux [Bordeaux], GHU AP-HP Centre Université de Paris, Institut Pascal (IP), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), CHU Clermont-Ferrand, Centre Hospitalier Princesse Grace, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier de Versailles André Mignot (CHV), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Centre Hospitalier Universitaire [Grenoble] (CHU), [GIN] Grenoble Institut des Neurosciences (GIN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), This work was funded by AP-HP (Assistance Publique des Hôpitaux de Paris), Fondation FondaMental (RTRS Santé Mentale), by the 'Investissements d’Avenir' programs managed by the Agence Nationale de Recherche (ANR), France under references ANR-11-IDEX-0004-02 and ANR-10-COHO-10-01, and by INSERM (Institut National de la Santé et de la Recherche Médicale)., ANR-10-COHO-0010,Psy-COH,FondaMental-Cohortes(2010), ANR-11-IDEX-0004,SUPER,Sorbonne Universités à Paris pour l'Enseignement et la Recherche(2011), BOHAUD, FRANCOISE, Cohortes - FondaMental-Cohortes - - Psy-COH2010 - ANR-10-COHO-0010 - COHO - VALID, and Sorbonne Universités à Paris pour l'Enseignement et la Recherche - - SUPER2011 - ANR-11-IDEX-0004 - IDEX - VALID

Subjects
Pediatrics, medicine.medical_specialty, medicine.drug_class, Substance-Related Disorders, Bipolar disorder, [SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, Functional Laterality, Dyslexia, Cognition, medicine, Humans, Pharmacology (medical), [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Child, Biological Psychiatry, Handedness, business.industry, Laterality, Neuropsychology, Mood stabilizer, General Medicine, medicine.disease, Substance abuse, Psychiatry and Mental health, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, Cohort, Language disorders, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], business, Neurocognitive, Body mass index
Abstract

International audience; Objectives: High rates of non-right-handedness (NRH) and mixed-handedness exist in neurodevelopmental disorders. Dysfunctional neurodevelopmental pathways may be implicated in the underlying pathophysiology of bipolar disorders (BD), at least in some subgroups. Yet little is known about correlates of NRH and mixed-handedness in BD. The objectives of this national study are to determine (i) the prevalence of NRH and mixed-handedness in a well-stabilized sample of BD individuals; (ii) if NRH/mixed-handedness in BD is associated with a different clinical, biological and neurocognitive profile.Methods: We included 2174 stabilized individuals. Participants were tested with a comprehensive battery of neuropsychological tests. Handedness was assessed using a single oral question. Learning and/or language disorders and obstetrical complications were recorded using childhood records. Common environmental, clinical and biological parameters were assessed.Results: The prevalence of NRH and mixed-handedness were, respectively, 11.6 and 2.4%. Learning/language disorders were found in 9.7% out of the total sample and were associated with atypical handedness (only dyslexia for mixed-handedness (p < 0.01), and dyslexia and dysphasia for NRH (p = 0.01 and p = 0.04, respectively). In multivariate analyses, NRH was associated with a younger age of BD onset (aOR 0.98 (95% CI 0.96-0.99) and lifetime substance use disorder (aOR 1.40 (95% CI 1.03-1.82) but not with any of the cognitive subtasks. Mixed-handedness was associated in univariate analyses with lifetime substance use disorder, lifetime cannabis use disorder (all p < 0.01) and less mood stabilizer prescription (p = 0.028). No association was found between NRH or mixed-handedness and the following parameters: trauma history, obstetrical complications, prior psychotic symptoms, bipolar subtype, attention deficit/hyperactivity disorder, peripheral inflammation or body mass index.Conclusions: Handedness may be associated with specific features in BD, possibly reflecting a specific subgroup with a neurodevelopmental load.

Published
2021
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14. Clinical characteristics of bipolar disorders with postpartum depressive onset

Author

Tebeka, Sarah, primary, Godin, Ophelia, additional, Mazer, Nicolas, additional, Bellivier, Frank, additional, Courtet, Philippe, additional, Etain, Bruno, additional, Gard, Sébastien, additional, Leboyer, Marion, additional, Llorca, Pierre-Michel, additional, Loftus, Joséphine, additional, Olié, Emilie, additional, Passerieux, Christine, additional, Polosan, Mircea, additional, Schwan, Raymund, additional, Belzeaux, Raoul, additional, Dubertret, Caroline, additional, Etain, B., additional, Henry, C., additional, Olié, E., additional, Leboyer, M., additional, Haffen, E., additional, Llorca, P.M., additional, Barteau, V., additional, Bensalem, S., additional, Godin, O., additional, Laouamri, H., additional, Souryis, K., additional, Hotier, S., additional, Pelletier, A., additional, Drancourt, N., additional, Sanchez, J.P., additional, Saliou, E., additional, Hebbache, C., additional, Petrucci, J., additional, Willaume, L., additional, Bourdin, E., additional, Bellivier, F., additional, Carminati, M., additional, Marlinge, E., additional, Meheust, J., additional, Antoniol, B., additional, Desage, A., additional, Gard, S., additional, Jutant, A., additional, Mbailara, K., additional, Minois, I., additional, Zanouy, L., additional, Abettan, C., additional, Bardin, L., additional, Cazals, A., additional, Courtet, P., additional, Deffinis, B., additional, Ducasse, D., additional, Gachet, M., additional, Henrion, A., additional, Martinerie, E., additional, Molière, F., additional, Noisette, B., additional, Tarquini, G., additional, Azorin, J.M., additional, Belzeaux, R., additional, Correard, N., additional, Consoloni, J.L., additional, Groppi, F., additional, Lescalier, L., additional, Montant, J., additional, Rebattu, M., additional, Viglianese, N., additional, Cohen, R., additional, Kahn, J.P., additional, Milazzo, M., additional, Wajsbrot-Elgrabli, O., additional, Bougerol, T., additional, Fredembach, B., additional, Suisse, A., additional, Halili, B., additional, Pouchon, A., additional, Polosan, M., additional, Galliot, A.M., additional, Grévin, I., additional, Cannavo, A.S., additional, Kayser, N., additional, Passerieux, C., additional, Roux, P., additional, Aubin, V., additional, Cussac, I., additional, Dupont, M.A., additional, Loftus, J., additional, Medecin, I., additional, Dubertret, C., additional, Mazer, N., additional, Portalier, C., additional, Scognamiglio, C., additional, and Bing, A., additional

Published
2021
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16. Trajectories of functioning in bipolar disorders: A longitudinal study in the FondaMental Advanced Centers of Expertise in Bipolar Disorders cohort

Author

Godin, Ophelia, primary, Leboyer, Marion, additional, Mazroui, Yassin, additional, Aouizerate, Bruno, additional, Azorin, Jean-Michel, additional, Raoul, Belzeaux, additional, Bellivier, Frank, additional, Polosan, Mircea, additional, Courtet, Philippe, additional, Dubertret, Caroline, additional, Henry, Chantal, additional, Kahn, Jean-Pierre, additional, Loftus, Josephine, additional, Olié, Emilie, additional, Passerieux, Christine, additional, Costagliola, Dominique, additional, Etain, Bruno, additional, Haffen, E., additional, Llorca, P.M., additional, Barteau, V., additional, Bensalem, S., additional, Laaidi, M., additional, Laouamri, H., additional, Souryis, K., additional, Hotier, S., additional, Pelletier, A., additional, Drancourt, N., additional, Sanchez, J.P., additional, Saliou, E., additional, Hebbache, C., additional, Petrucci, J., additional, Willaume, L., additional, Bourdin, E., additional, Carminati, M., additional, Etain, B., additional, Marlinge, E., additional, Meheust, J., additional, Antoniol, B., additional, Desage, A., additional, Gard, S., additional, Jutant, A., additional, Mbailara, K., additional, Minois, I., additional, Zanouy, L., additional, Abettan, C., additional, Bardin, L., additional, Cazals, A., additional, Deffinis, B., additional, Ducasse, D., additional, Gachet, M., additional, Henrion, A., additional, Martinerie, E., additional, Molière, F., additional, Noisette, B., additional, Tarquini, G., additional, Belzeaux, R., additional, Correard, N., additional, Consoloni, J. L., additional, Groppi, F., additional, Lescalier, L., additional, Montant, J., additional, Rebattu, M., additional, Viglianese, N., additional, Cohen, R., additional, Milazzo, M., additional, Wajsbrot-Elgrabli, O., additional, Bougerol, T., additional, Fredembach, B., additional, Garçon, S., additional, Grignon, P., additional, Perrin, A., additional, Galliot, A.M., additional, Grévin, I., additional, Cannavo, A.S., additional, Kayser, N., additional, Roux, P., additional, Aubin, V., additional, Cussac, I., additional, Dupont, M.A., additional, Medecin, I., additional, Mazer, N., additional, and Portalier, C., additional

Published
2020
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26. NLX-112, a highly selective 5-HT1A receptor agonist, mediates analgesia and antidepressant-like activity in rats via spinal cord and prefrontal cortex 5-HT1A receptors, respectively.

Author

Newman-Tancredi, A., Bardin, L., Auclair, A., Colpaert, F., Depoortère, R., and Varney, M.A.

Subjects
*NEUROLOGICAL disorder prevention, *TRYPTAMINE, *ANALGESICS, *DRUG efficacy, *PREFRONTAL cortex, *ANTIDEPRESSANTS, *THERAPEUTICS
Abstract

NLX-112 (a.k.a. F13640 or befiradol) possesses marked activity in a variety of animal models of pain and of neuropsychiatric disorders; it exhibits nanomolar affinity, exceptional selectivity and high agonist efficacy at 5-hydroxytryptamine1A (5–HT 1A ) receptors. Although NLX-112 has been shown to activate 5-HT 1A postsynaptic heteroreceptors in the prefrontal cortex (PFC), a brain region involved in the control of depressive states, the influence of NLX-112 on spinal cord 5-HT 1A receptors (implicated in the control of pain) has not been described. Here we report on the ability, in rats, of NLX-112 to elicit analgesia in the intraplantar formalin model of nociceptive pain following intrathecal (i.t.) administration, and its ability to produce antidepressant-like activity in the forced swim test (FST) following in situ PFC microinjection. NLX-112, injected i.t. (L5-L6 region) induced analgesic effects in the formalin model of tonic nociceptive pain. At 20 µg, it almost abolished the effect of formalin on both the paw licking and paw elevation measures, and in both the early (0–5 min after formalin administration, reflecting acute pain) and the late (22.5–27.5 min, reflecting inflammatory pain) phases. The effects of NLX-112 (20 µg i.t.) were reversed by co-administration of 20 µg i.t. of the 5-HT 1A receptor antagonist, WAY100635. Furthermore, the analgesic effects of systemically administered NLX-112 (0.63 mg/kg i.p.) were reversed by i.t. administration of WAY100635 (20 µg), most notably on paw licking. Finally, microinjection of NLX-112, bilaterally in the PFC, dose-dependently (MED 4 µg) and markedly reduced immobility in the FST (circa 90% reduction at 32 µg). In conclusion, the present data demonstrate that activation of spinal cord-located 5-HT 1A receptors is sufficient for NLX-112 to mediate its analgesic effects in a rat model of tonic nociceptive pain. The data also highlight the involvement of PFC 5-HT 1A receptors in the antidepressant-like activity of NLX-112 in the FST. Overall, the study suggests that highly selective and high efficacy 5–HT 1A receptors agonists, such as NLX-112, could be useful to treat painful conditions associated with depressive states, through activation of different sub-populations of 5-HT 1A receptors. [ABSTRACT FROM AUTHOR]

Published
2018
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28. Medial arch supports do not significantly alter the knee adduction moment in people with knee osteoarthritis

Author

Hinman, RS, Bardin, L, Simic, M, Bennell, KL, Hinman, RS, Bardin, L, Simic, M, and Bennell, KL

Abstract

OBJECTIVE: This study aimed to evaluate the immediate effects of medial arch supports on indices of medial knee joint load (the peak external knee adduction moment (KAM) and knee adduction angular (KAA) impulse) and knee pain during walking in people with medial knee osteoarthritis (OA). DESIGN: Twenty-one people with medial compartment OA underwent gait analysis in standardised athletic shoes wearing (1) no medial arch supports and (2) prefabricated medial arch supports, in random order. Outcomes were the first and second peaks in the external KAM, the KAA impulse and severity of knee pain during testing. Outcomes were compared across conditions using paired t tests (gait data) and Wilcoxon Signed Ranks test (pain data). RESULTS: There were no significant changes in either first or second peak KAM, or in the KAA impulse, with the addition of medial arch supports (all P > 0.05). Considerable individual variation in response to the arch supports was observed across participants. There was no immediate change in knee pain during walking when medial arch supports were worn (P = 0.56). CONCLUSIONS: This study showed no mean change in any of the measured indices of medial knee load with medial arch supports. No immediate changes in knee pain were evident.

Published
2013

29. Magnesium deficiency induces on hyperalgesia reversed by the NMDA receptor antagonist MK801

Author

Dubray, C., Alloui, A., Bardin, L., Rock, Edmond, Mazur, André, Rayssiguier, Yves, Eschalier, A., Lavarenne, J., Unité de recherche Maladies Métaboliques et Micronutriments (U3M), Institut National de la Recherche Agronomique (INRA), and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], RECEPTEUR DU N METHYL D ASPARTATE, [SDV]Life Sciences [q-bio], RAT, NEUROPHYSIOLOGIE, MK801
Published
1997

42. P.3.d.007 F15063, a novel antipsychotic with dopamine D2/D3 antagonist, 5-HT1A agonist and D4 partial agonist properties: III. Duration of brain D2-like receptor occupancy, antipsychotic-like activity and plasma concentration in rodents

Author

Assié, M.B., primary, Bardin, L., additional, Auclair, A.L., additional, Consul-Denjean, N., additional, Sautel, F., additional, Kleven, M.S., additional, Depoortere, R., additional, and Newman-Tancredi, A., additional

Published
2006
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