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1. Successful immunosuppressive drug‐free immune tolerance induction in hemophilia B with inhibitor and anaphylaxis to factor IX: A case report.

Author

Palomo Bravo, Ángeles, Prieto Bonilla, Rosario, Bardan Rebollar, Daniel, López‐Jaime, Francisco José, and Fernández‐Bello, Ihosvany

Subjects
BLOOD coagulation factor IX, IMMUNOLOGICAL tolerance, MEDICAL protocols, HEMOPHILIA, ANAPHYLAXIS
Abstract

Key Clinical Message: Recommendations advise factor IX desensitization before immune tolerance induction in severe hemophilia B, supported by immunosuppression. A child with inhibitor and anaphylaxis to factor IX showed successful immunosuppression‐free immune tolerance induction using very low and slowly increasing doses of a factor IX extended‐half‐life product. Immune tolerance to factor IX based on this protocol merits further study. [ABSTRACT FROM AUTHOR]

Published
2024
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