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Nesse trabalho abordamos a obtenção do material cerâmico Gd2Mo3O12 na sua fase beta, denominado beta-GMO, utilizando-se do método convencional de mistura de óxidos e reação do estado sólido. MoO3 e o Gd2O3 nas razões molares 3:1 e 3,25:1 foram usados como pós de partida. Cerâmicas sinterizadas foram usadas como pedestais e sementes na produção de fibras monocristalinas pela técnica Laser Heated Pedestal Growth- LHPG. A cerâmica com fase única Gd2Mo3O12 foi melhor obtida usando a razão molar 3:1 entre os pós de partida. Por outro lado, fibras cristalinas obtidas a partir de pedestais cerâmicos com excesso de MoO3 apresentaram melhor qualidade óptica e a estequiometria desejada.

The production of high-density Bi 12TiO20 ceramics, their transmission spectrum, and impedance features are reported. The samples were synthesized at 700°C/6 h and sintered at 800°C/3 h. This procedure yielded translucent ceramics with relative density of 99.2 ± 0.5% and average grain size of 3.1 ± 1.6μm. Samples with 0.5 mm thickness were translucent with optical transmission of about 30% at 800 nm. The electrical and dielectric properties of the high-density ceramics were studied and compared with those measured for samples with lower density and also with the literature about Bi 12TiO20 single crystals. The activation energy for the conduction process in high-density ceramic was 0.99 eV, and the dielectric permittivity was 40 at 200°C. These values are comparable to those reported for single crystals. [ABSTRACT FROM AUTHOR]

When compared to other model organisms whose genome is sequenced, the number of mutations identified in the mouse appears extremely reduced and this situation seriously hampers our understanding of mammalian gene function(s). Another important consequence of this shortage is that a majority of human genetic diseases still await an animal model. To improve the situation, two strategies are currently used: the first makes use of embryonic stem cells, in which one can induce knockout mutations almost at will; the second consists of a genome-wide random chemical mutagenesis, followed by screening for mutant phenotypes and subsequent identification of the genetic alteration(s). Several projects are now in progress making use of one or the other of these strategies. Here, we report an original effort where we mutagenized BALB/c males, with the mutagen ethylnitrosourea. Offspring of these males were screened for dominant mutations and a three-generation breeding protocol was set to recover recessive mutations. Eleven mutations were identified (one dominant and ten recessives). Three of these mutations are new alleles (Otop1mlh, Foxn1sepe and probably rodador) at loci where mutations have already been reported, while 4 are new and original alleles (carc, eqlb, frqz, and Sacc). This result indicates that the mouse genome, as expected, is far from being saturated with mutations. More mutations would certainly be discovered using more sophisticated phenotyping protocols. Seven of the 11 new mutant alleles induced in our experiment have been localized on the genetic map as a first step towards positional cloning.