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Your search keyword '"Barbara L, Parsons"' showing total 88 results

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1. Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

2. A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

3. Outgrowth of erlotinib-resistant subpopulations recapitulated in patient-derived lung tumor spheroids and organoids

4. Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal Carcinomas

5. Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing

6. Quantification of cancer driver mutations in human breast and lung <scp>DNA</scp> using targeted, error‐corrected <scp>CarcSeq</scp>

7. Rationale and Roadmap for Developing Panels of Hotspot Cancer Driver Gene Mutations as Biomarkers of Cancer Risk

8. A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

9. CarcSeq Measurement of Rat Mammary Cancer Driver Mutations and Relation to Spontaneous Mammary Neoplasia

11. Modern conception of carcinogenesis creates opportunities to advance cancer risk assessment

12. LifespanKrasmutation levels in lung and liver of B6C3F1mice

13. Variation in organ-specificPIK3CAandKRASmutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas

14. Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations

15. ACB-PCR Quantification of Low-Frequency Hotspot Cancer-Driver Mutations

16. ACB-PCR Quantification of Low-Frequency Hotspot Cancer-Driver Mutations

17. Low-Frequency Mutational Heterogeneity of Invasive Ductal Carcinoma Subtypes: Information to Direct Precision Oncology

19. Multiclonal tumor origin: Evidence and implications

20. Quantification of Kras mutant fraction in the lung DNA of mice exposed to aerosolized particulate vanadium pentoxide by inhalation

21. Lifespan Kras mutation levels in lung and liver of B6C3F

22. Ovarian effects of prenatal exposure to benzo[a]pyrene: Roles of embryonic and maternal glutathione status

23. Variation in organ-specific PIK3CA and KRAS mutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas

24. Temporal Changes in K-ras Mutant Fraction in Lung Tissue of Big Blue B6C3F1 Mice Exposed to Ethylene Oxide

25. ACB-PCR measurement of spontaneous and furan-induced H-rasCodon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liver

26. Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations

27. A subset of papillary thyroid carcinomas containKRASmutant subpopulations at levels above normal thyroid

28. ACB-PCR measurement of H-ras codon 61 CAA→CTA mutation provides an early indication of aristolochic acid I carcinogenic effect in tumor target tissues

29. p53 codon 271 CGT to CAT mutant fraction does not increase in nasal respiratory and olfactory epithelia of rats exposed to inhaled naphthalene

30. Oncomutations as biomarkers of cancer risk

31. K-RAS mutation in the screening, prognosis and treatment of cancer

32. Many different tumor types have polyclonal tumor origin: Evidence and implications

33. Simulated solar light‐inducedp53mutagenesis in SKH‐1 mouse skin: A dose–response assessment

34. Low-frequency KRAS mutations are prevalent in lung adenocarcinomas

35. ACB-PCR measurement of K-ras codon 12 mutant fractions in livers of Big Blue(R) rats treated with N-hydroxy-2-acetylaminofluorene

36. Frequency and types of spontaneous Hprt lymphocyte mutations in Pms2-deficient mice

37. Levels of H-ras codon 61 CAA to AAA mutation: response to 4-ABP-treatment and Pms2-deficiency

38. 4-Aminobiphenyl induces liver DNA adducts in both neonatal and adult mice but induces liver mutations only in neonatal mice

39. Levels of 4-aminobiphenyl-induced somatic H-ras mutation in mouse liver DNA correlate with potential for liver tumor development

40. Quantifying levels ofp53 mutation in mouse skin tumors

41. Pms2 deficiency results in increased mutation in the Hprt gene but not the Tk gene of Tk+/- transgenic mice

42. Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression

43. ACB-PCR quantification of somatic oncomutation

44. Prospects for applying genotypic selection of somatic oncomutation to chemical risk assessment

45. Detection of basepair substitution mutation at a frequency of 1 × 10−7 by combining two genotypic selection methods, MutEx enrichment and allele-specific competitive blocker PCR

46. ACB-PCR Quantification of Somatic Oncomutation

47. Evaluation of MutS as a tool for direct measurement of point mutations in genomic DNA

48. Temporal changes in K-ras mutant fraction in lung tissue of big blue B6C3F₁ mice exposed to ethylene oxide

49. Personalized cancer treatment and the myth of KRAS wild-type colon tumors

50. ACB-PCR measurement of spontaneous and furan-induced H-ras codon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liver

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