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In order to explore the effect of Chuzhou chrysanthemum powder application in bread processing on dough characteristics and bread flavor and antioxidant activity, the thermal and mechanical properties of dough with added Chuzhou chrysanthemum powder were measured using Mixolab 2, and the volatile flavor compounds in the resulting bread were analyzed by gas chromatography-ion mobility spectrometry (GC-IMS). In addition, the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS) cation radical scavenging capacity and the total flavonoid content of the bread were determined. The results showed that the water absorption rate of dough significantly increased while the peak viscosity and setback of starch decreased upon addition of Chuzhou chrysanthemum powder. Compared with the control bread, the content of flavor components in Chuzhou chrysanthemum incorporated bread was higher, and d-camphor was found to be the characteristic flavor component of Chuzhou chrysanthemum. The volatile flavor components in the samples with and without Chuzhou chrysanthemum were obviously different according to principal component analysis (PCA). The total flavonoid content of Chuzhou chrysanthemum incorporated bread was 260.47 mg/100 g, which was significantly higher than that of the control bread, and the DPPH and ABTS cation radical scavenging activities were higher than those of the control bread. In conclusion, addition of Chuzhou chrysanthemum powder to bread can enrich the flavor components and improve the antioxidant activity of bread, which provides a reference for the application of Chuzhou chrysanthemum in bakery foods.

Extracellular vesicles (EVs) have emerged as promising biomaterials for the treatment of different disease. However, only handful types of EVs with clinical transformation potential have been reported to date, and their preparation on a large scale under biosafety‐controlled conditions is limited. In this study, we characterize a novel type of EV with promising clinical application potential: dehydration‐induced extracellular vesicles (DIMVs). DIMV is a type of micron‐diameter cell vesicle that contains more bioactive molecules, such as proteins and RNA, but not DNA, than previously reported cell vesicles. The preparation of DIMV is extraordinarily straightforward, which possesses a high level of biosafety, and the protein utilization ratio is roughly 600 times greater than that of naturally secreted EVs. Additional experiments demonstrate the viability of pre‐ or post‐isolation DIMV modification, including gene editing, nucleic acid encapsulation or surface anchoring, size adjustment. Finally, on animal models, we directly show the biosafety and immunogenicity of DIMV, and investigate its potential application as tumour vaccine or drug carrier in cancer treatment. [ABSTRACT FROM AUTHOR]

A Sr(II) complex [Sr(L)2 (H2O)4 ]n (1) was synthesized with 1,4,5,8-naphthalene tetracarboxylic acid (H4L1) and strontium chloride hexahydrate under solvothermal conditions. The structure was characterized by elemental analysis (EA), single crystal X-ray diffraction (SXRD), powder X-ray diffraction (PXRD), infrared spectroscopy (IR) and thermogravimetric analysis (TGA). The single crystal X-ray diffraction results indicate that H2L1 undergoes in-situ reaction to generate 1,3-dioxo-1H,3H-benzo[de]isomere-6,7-dicarboxylic acid (H2L). In complex 1, each Sr(II) atom is located in the geometric configuration of a square antiprism. The L- ligands connect Sr atoms to form a one-dimensional chain structure. 2D supramolecular structure is formed through hydrogen bonding and π ... π stacking interactions. The solid states luminescence behavior of complex 1 was explored. It is found that complex 1 produces a wide emission spectrum band (450-690 nm) at the excitation wavelength of 211 nm, and the maximum emission wavelength appears at 535 nm. Therefore, it can be seen that complex 1 is a potential green light material. [ABSTRACT FROM AUTHOR]

To systematically research the impact of Tai Chi intervention on cognitive rehabilitation of elderly adults with mild cognitive impairment (MCI). Both English and Chinese databases were systematically searched from inception to December 2019: MEDLINE, EMBASE, the Cochrane Library, Web of Science, SinoMed database, China National Knowledge Infrastructure, Traditional Chinese Medicine clinical evidence database, Wanfang knowledge database, Chinese Science and Technology Periodical Database. Randomized controlled trials (RCTs) and quasi-experimental studies that involved older adults with MCI, Tai Chi intervention, and cognitive rehabilitation outcomes were included. The meta-analysis was conducted and reported according to PRISMA guidelines (PROSPERO registration number CRD42019124925). Twelve studies were included. For the meta-analysis, Tai Chi exercise had a large beneficial effect on global cognitive ability and long-term delayed recall ability from the memory domain. In terms of executive ability, Tai Chi intervention had a moderate and significant effect on improving patients' executive function. The results suggest a Tai Chi intervention lasting at least 12 weeks with a frequency of three times per week and 30–60 min per session. Tai Chi shows promise as an alternative mind-body intervention for MCI rehabilitation among elder patients. From a global perspective, Tai Chi may be an effective mind-body exercise for cognitive rehabilitation among elder patients with MCI, which is not restricted by the condition of equipment, manpower, and venue. This review suggests an intervention that includes a warm-up, exercise, and cool-down period and lasts at least 12 weeks with a frequency of three times per week and 30–60 min per session. It is also recommended to choose suitable training methods according to local conditions, including one-to-one coaching, group training, VCD, and visual reality technology for some developed regions. [ABSTRACT FROM AUTHOR]