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Aim • To find changes in hematologic parameters in patients who are COVID-19-positive with respect to high resolution computed tomography (HRCT) chest scan so that the exact picture of the disease course can be identified and an adequate treatment protocol can be planned to combat the COVID-19 pandemic. Methods • Patients’ health-related data including age, gender, symptomatology, associated co-morbidities, laboratory test results and HRCT results were collected. Results • The radiologic findings showed ground glass opacities (GGOs) was the most common manifestation. Analysis of HRCTs of patients with COVID-19 showed that lesions were mainly confined to the right and left lower lobes, suggesting that the COVID-19 virus is mainly harbored in the basal areas of the lungs. Conclusion • Radiologic and laboratory investigations can greatly help in early detection of COVID-19, thus allowing for timely interventions. (Altern Ther Health Med. 2021;27(S1):204-209) [ABSTRACT FROM AUTHOR]

Introduction: Corona virus belongs to the family of viruses that may cause various symptoms such as pneumonia, fever, breathing difficulty, and lung infection(1). The outbreak of coronavirus disease (COVID-19) was first reported on December 31, 2019, in Wuhan, China(2). On January 30, 2020, the World Health Organization (WHO) declared COVID-19, a Public Health Emergency of International Concern (PHEIC) and thus a pandemic(3). India reported its First case on 30 January, 2020; a medical student who had travelled from Wuhan, China, the epicenter of COVID-19 Methodology: It is a retrospective, hospital based study conducted from 25 November 2020 to 15 December 2020 in J.L.N Medical College and Associated Group of Hospitals, Ajmer. A total of 118 Laboratory confirmed Covid-19 cases who underwent chest CT were taken in the study. Results and Conclusion: From present study it can conclude that the constancy of CT chest findings is related to duration of illness. It also shows that time course of infection is of utmost importance not onlyto understand the pathophysiologic features and natural history of disease, but also help to predict the disease in its early stages and to prevent potential complications. As the disease is very virulent and potentially fatal, the risk stratification through CT chest is necessary so during triage, CT should be done as early as possible along with RT-PCR so that early detection of disease provides window for early initiation of treatment thus avoiding complications especially in co-morbid patients. [ABSTRACT FROM AUTHOR]

Context • Inflammation is a significant factor driving the rise of multiple cases of viral pneumonia, including COVID-19 infection. Peripheral white blood cells (WBCs), the neutrophil (NEU)-to-lymphocyte (LYM) ratio (NLR), the platelet-to-lymphocyte (PLR) ratio, and hemoglobin (Hb) are markers of systematic inflammatory reaction and often predict disease severity. Objective • The current study intended to examine the prognostic importance of hemoglobin (Hb), total leukocyte count (TLC), absolute neutrophile count (ANC), absolute lymphocyte count (ALC), NLR, d-NLR [derived NLR = ANC/(WBC-ANC)], absolute platelet count (APC), and PLR, based on complete blood counts (CBCs) for COVID-19 patients. Design • The research team designed a retrospective that was conducted between March 27 and June 5, 2020, after the first COVID-19 case was reported in Ajmer, Rajasthan, India on March 27. Setting • The study took place at Jawaharlal Nehru (JLN) Medical College in Ajmer, Rajasthan, India. Participants • The study included 364 participants who were all COVID-positive patients who came to the hospital during the study’s period, including patients from various age groups and of both genders. Outcome Measures • Using the results of the CBC, the research team measured: (1) Hb in g/dl, (2) ANC, (3) ALC, and (4) APC. The neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) were calculated from measurements of the levels of the circulating biomarkers, as cells × 103/μl. Result • For participants who were severely symptomatic, the mean age was 57.86 ± 8.92. Males were more likely to experience severe symptoms. Participants’ Hb values were significantly different between groups, and TLC, ANC, NLR, d-NLR, and PLR were highest in the severely symptomatic group and lowest in the asymptomatic group. NLR was positively associated with a risk of COVID-19 pneumonia, while Hb was negatively associated with development of pneumonia. Conclusions • Disease severity and age are independent predictors of poor outcomes. The NLR should be used as a routine blood test that can help in the diagnosis of disease severity in COVID-19. NLR is very simple tool that can be used as a fast and low-cost test that is easily available, even in small centers where the facilities for other tests, such as tests of LDH, CRP, and IL‐6, and high resolution CT scans aren’t available. Thus, NLR can be used as single independent predictor of COVID-19 disease severity. [ABSTRACT FROM AUTHOR]

Context: Inflammation is a significant factor driving the rise of multiple cases of viral pneumonia, including COVID-19 infection. Peripheral white blood cells (WBCs), the neutrophil (NEU)-to-lymphocyte (LYM) ratio (NLR), the platelet-to-lymphocyte (PLR) ratio, and hemoglobin (Hb) are markers of systematic inflammatory reaction and often predict disease severity., Objective: The current study intended to examine the prognostic importance of hemoglobin (Hb), total leukocyte count (TLC), absolute neutrophile count (ANC), absolute lymphocyte count (ALC), NLR, d-NLR [derived NLR = ANC/(WBC-ANC)], absolute platelet count (APC), and PLR, based on complete blood counts (CBCs) for COVID-19 patients., Design: The research team designed a retrospective that was conducted between March 27 and June 5, 2020, after the first COVID-19 case was reported in Ajmer, Rajasthan, India on March 27., Setting: The study took place at Jawaharlal Nehru (JLN) Medical College in Ajmer, Rajasthan, India., Participants: The study included 364 participants who were all COVID-positive patients who came to the hospital during the study's period, including patients from various age groups and of both genders., Outcome Measures: Using the results of the CBC, the research team measured: (1) Hb in g/dl, (2) ANC, (3) ALC, and (4) APC. The neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) were calculated from measurements of the levels of the circulating biomarkers, as cells × 103/μl., Result: For participants who were severely symptomatic, the mean age was 57.86 ± 8.92. Males were more likely to experience severe symptoms. Participants' Hb values were significantly different between groups, and TLC, ANC, NLR, d-NLR, and PLR were highest in the severely symptomatic group and lowest in the asymptomatic group. NLR was positively associated with a risk of COVID-19 pneumonia, while Hb was negatively associated with development of pneumonia., Conclusions: Disease severity and age are independent predictors of poor outcomes. The NLR should be used as a routine blood test that can help in the diagnosis of disease severity in COVID-19. NLR is very simple tool that can be used as a fast and low-cost test that is easily available, even in small centers where the facilities for other tests, such as tests of LDH, CRP, and IL-6, and high resolution CT scans aren't available. Thus, NLR can be used as single independent predictor of COVID-19 disease severity.