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1. New Strong Gravitational Lenses from the DESI Legacy Imaging Surveys Data Release 9

Author

Storfer, C, Huang, X, Gu, A, Sheu, W, Banka, S, Dey, A, Reyes, J Inchausti, Jain, A, Kwon, KJ, Lang, D, Lee, V, Meisner, A, Moustakas, J, Myers, AD, Tabares-Tarquinio, S, Schlafly, EF, and Schlegel, DJ

Subjects
Astronomical Sciences, Physical Sciences, Biomedical Imaging, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physical Chemistry (incl. Structural), Astronomy & Astrophysics, Astronomical sciences
Abstract

We have conducted a search for strong gravitational lensing systems in the Dark Energy Spectroscopic Instrument (DESI) Legacy Imaging Surveys Data Release 9. This is the third paper in a series. These surveys together cover ∼19,000 deg2 visible from the Northern Hemisphere, reaching a z-band AB magnitude of ∼22.5. We use a deep residual neural network, trained on a compilation of known lensing systems and high-grade candidates as well as nonlenses in the same footprint. After applying our trained neural network to the survey data, we visually inspect and rank images with probabilities above a threshold which has been chosen to balance precision and recall. We have found 1895 lens candidates, of which 1512 are identified for the first time. Combining the discoveries from this work with those from Papers I (335) and II (1210), we have discovered a total of 3057 new candidates in the Legacy Surveys.

Published
2024

3. Overcoming Post-War Traumas and Confl icts through Dialogue in Distributed Cognition

Author

Banka Augustine

Subjects
trauma, therapy culture, post-traumatic stress, distributed cognition, dialogue, Political science, Social history and conditions. Social problems. Social reform, HN1-995
Abstract

The following paper presents a proposal of a theoretical foundation for an application of distributed cognition in overcoming post-war traumas and related social conflicts. The distributed cognition theory states that the cognitive system is a structure distributed between internal-mental and external-objective social world representations across time and space. The basic issue of dialogue in distributed cognition is that distribution as information dissemination in each cognitive component functions in a systemic integrity. The presented perspective of overcoming traumas and war conflicts through dialogue refers to the following aspects of human activity: 1 - the perception of an environment as a construct of own life path and self-image; 2 - active creation of a desired world, life space and desired self; 3 - agentic cognitive mapping of an environment as a real, virtual and potential life space; 4 - a way of elastic control over an environment through discovering objectively present environmental affordances; 5 - achieving agency through discovering possibilities for action rather than barriers; 6 - making the cognitive system more flexible through a change in style of thinking to a constant state of openness to new meanings and values.

Published
2017
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6. A Systematic Review of Deep Graph Neural Networks: Challenges, Classification, Architectures, Applications & Potential Utility in Bioinformatics

Author

Malla, Adil Mudasir and Banka, Asif Ali

Subjects
Computer Science - Machine Learning, Computer Science - Artificial Intelligence, Quantitative Biology - Quantitative Methods
Abstract

In recent years, tasks of machine learning ranging from image processing & audio/video analysis to natural language understanding have been transformed by deep learning. The data content in all these scenarios are expressed via Euclidean space. However, a considerable amount of application data is structured in non-Euclidean space and is expressed as graphs, e.g. dealing with complicated interactions & object interdependencies. Modelling physical systems, learning molecular signatures, identifying protein interactions and predicting diseases involve utilising a model that can adapt from graph data. Graph neural networks (GNNs), specified as artificial-neural models, employ message transmission between graph nodes to represent graph dependencies and are primarily used in the non-Euclidean domain. Variants of GNN like Graph Recurrent Networks (GRN), Graph Auto Encoder (GAE), Graph Convolution Networks (GCN), Graph Adversarial Methods & Graph Reinforcement learning have exhibited breakthrough productivity on a wide range of tasks, especially in the field of bioinformatics, in recent years as a result of the rapid collection of biological network data. Apart from presenting all existing GNN models, mathematical analysis and comparison of the variants of all types of GNN have been highlighted in this survey. Graph neural networks are investigated for their potential real-world applications in various fields, focusing on Bioinformatics. Furthermore, resources for evaluating graph neural network models and accessing open-source code & benchmark data sets are included. Ultimately, we provide some (seven) proposals for future research in this rapidly evolving domain. GNNs have the potential to be an excellent tool for solving a wide range of biological challenges in bioinformatics research, as they are best represented as connected complex graphs., Comment: 39 pages, 13 figures, 21 tables

Published
2023

7. Global Practice Patterns in the Evaluation of Non-Obstructive Azoospermia: Results of a World-Wide Survey and Expert Recommendations

Author

Rupin Shah, Amarnath Rambhatla, Widi Atmoko, Marlon Martinez, Imad Ziouziou, Priyank Kothari, Nicholas Tadros, Nguyen Ho Vinh Phuoc, Parviz Kavoussi, Ahmed Harraz, Gianmaria Salvio, Murat Gul, Taha Hamoda, Tuncay Toprak, Ponco Birowo, Edmund Ko, Mohamed Arafa, Ramy Abou Ghayda, Vilvapathy Senguttuvan Karthikeyan, Ramadan Saleh, Giorgio Ivan Russo, Germar-Michael Pinggera, Eric Chung, Missy Savira, Giovanni M. Colpi, Wael Zohdy, Edoardo Pescatori, Hyun Jun Park, Shinichiro Fukuhara, Akira Tsujimura, Cesar Rojas-Cruz, Angelo Marino, Siu King Mak, Edouard Amar, Wael Ibrahim, Puneet Sindhwani, Naif Alhathal, Gian Maria Busetto, Manaf Al Hashimi, Ahmed El-Sakka, Asci Ramazan, Fotios Dimitriadis, Massimiliano Timpano, Davor Jezek, Baris Altay, Daniel Suslik Zylbersztejn, Michael YC Wong, Du Geon Moon, Christine Wyns, Safar Gamidov, Hamed Akhavizadegan, Alessandro Franceschelli, Kaan Aydos, Vinh Nguyen Quang, Shedeed Ashour, Adel Al Dayel, Mohamed S. Al-Marhoon, Sava Micic, Saleh Binsaleh, Alayman Hussein, Haitham Elbardisi, Taymour Mostafa, Emad Taha, Jonathan Ramsay, Athanasios Zachariou, Islam Fathy Soliman Abdelrahman, Osvaldo Rajmil, Arif Kalkanli, Juan Manuel Corral Molina, Kadir Bocu, Gede Wirya Kusuma Duarsa, Gokhan Ceker, Ege Can Serefoglu, Fahmi Bahar, Nazim Gherabi, Shinnosuke Kuroda, Abderrazak Bouzouita, Ahmet Gudeloglu, Erman Ceyhan, Mohamed Saeed Mohamed Hasan, Muhammad Ujudud Musa, Ahmad Motawi, Cho Chak-Lam, Hisanori Taniguchi, Christopher Chee Kong Ho, Jesus Fernando Solorzano Vazquez, Shingai Mutambirwa, Nur Dokuzeylul Gungor, Marion Bendayan, Carlo Giulioni, Aykut Baser, Marco Falcone, Luca Boeri, Gideon Blecher, Alireza Kheradmand, Tamilselvi Sethupathy, Ricky Adriansjah, Nima Narimani, Charalampos Konstantinidis, Tuan Thanh Nguyen, Andrian Japari, Parisa Dolati, Keerti Singh, Cevahir Ozer, Selcuk Sarikaya, Nadia Sheibak, Ndagijimana Jean Bosco, Mehmet Serkan Özkent, Sang Thanh Le, Ioannis Sokolakis, Darren Katz, Ryan Smith, Manh Nguyen Truong, Tan V. Le, Zhongwei Huang, Muslim Dogan Deger, Umut Arslan, Gokhan Calik, Giorgio Franco, Ayman Rashed, Oguzhan Kahraman, Sotiris Andreadakis, Rosadi Putra, Giancarlo Balercia, Kareim Khalafalla, Rossella Cannarella, Anh Đặng Tuấn, Amr El Meliegy, Birute Zilaitiene, Marlene Lizbeth Zamora Ramirez, Filippo Giacone, Aldo E. Calogero, Konstantinos Makarounis, Sunil Jindal, Bac Nguyen Hoai, Ravi Banthia, Marcelo Rodriguez Peña, Dharani Moorthy, Aram Adamyan, Deniz Kulaksiz, Hussein Kandil, Nikolaos Sofikitis, Ciro Salzano, Andreas Jungwirth, Surendra Reddy Banka, Tiago Cesar Mierzwa, Tahsin Turunç, Divyanu Jain, Armen Avoyan, Pietro Salacone, Ateş Kadıoğlu, Chirag Gupta, Haocheng Lin, Iman Shamohammadi, Nasser Mogharabian, Trenton Barrett, Yavuz Onur Danacıoğlu, Andrea Crafa, Salima Daoud, Vineet Malhotra, Abdulmalik Almardawi, Osama Mohamed Selim, Mohamad Moussa, Saeid Haghdani, Mesut Berkan Duran, Yannic Kunz, Mirko Preto, Elena Eugeni, Thang Nguyen, Ahmed Rashad Elshahid, Seso Sulijaya Suyono, Dyandra Parikesit, Essam Nada, Eduardo Gutiérrez Orozco, Florence Boitrelle, Nguyen Thi Minh Trang, Mounir Jamali, Raju Nair, Mikhail Ruzaev, Franco Gadda, Charalampos Thomas, Raphael Henrique Ferreira, Umit Gul, Serena Maruccia, Ajay Kanbur, Ella Kinzikeeva, Saad Abumelha, Nguyen Quang, Raghavender Kosgi, Fatih Gokalp, Mohammad Ayodhia Soebadi, Gustavo Marquesine Paul, Hesamoddin Sajadi, Deepak Gupte, Rafael F. Ambar, Emrullah Sogutdelen, Karun Singla, Ari Basurkano, Shannon Hee Kyung Kim, Mohammad Ali Sadighi Gilani, Koichi Nagao, Sakti Ronggowardhana Brodjonegoro, Andri Rezano, Mohamed Elkhouly, Rossella Mazzilli, Hasan M. A. Farsi, Hung Nguyen Ba, Hamed Alali, Dimitrios Kafetzis, Tran Quang Tien Long, Sami Alsaid, Hoang Bao Ngoc Cuong, Knigavko Oleksandr, Akhmad Mustafa, Herik Acosta, Hrishikesh Pai, Bahadır Şahin, Eko Arianto, Colin Teo, Sanjay Prakash Jayaprakash, Rinaldo Indra Rachman, Mustafa Gurkan Yenice, Omar Sefrioui, Smit Paghdar, Shivam Priyadarshi, Marko Tanic, Noor Kareem Alfatlawy, Fikri Rizaldi, Ranjit B. Vishwakarma, George Kanakis, Dinesh Thomas Cherian, Joe Lee, Raisa Galstyan, Hakan Keskin, Jana Wurzacher, Doddy Hami Seno, Bambang S. Noegroho, Ria Margiana, Qaisar Javed, Fabrizio Castiglioni, Raman Tanwar, Ana Puigvert, Coşkun Kaya, Medianto Purnomo, Chadi Yazbeck, Azwar Amir, Edson Borges, Marina Bellavia, Isaac Ardianson Deswanto, Vinod K V, Giovanni Liguori, Dang Hoang Minh, Kashif Siddiqi, Fulvio Colombo, Armand Zini, Niket Patel, Selahittin Çayan, Ula Al-Kawaz, Maged Ragab, Guadalupe Hernández Hebrard, Ivan Hoffmann, Ozan Efesoy, Barış Saylam, and Ashok Agarwal

Subjects
azoospermia, diagnosis, guideline, infertility, male, surveys and questionnaires, Medicine, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Purpose: Non-obstructive azoospermia (NOA) represents the persistent absence of sperm in ejaculate without obstruction, stemming from diverse disease processes. This survey explores global practices in NOA diagnosis, comparing them with guidelines and offering expert recommendations. Materials and Methods:Materials and Methods: A 56-item questionnaire survey on NOA diagnosis and management was conducted globally from July to September 2022. This paper focuses on part 1, evaluating NOA diagnosis. Data from 367 participants across 49 coun-tries were analyzed descriptively, with a Delphi process used for expert recommendations. Results:Results: Of 336 eligible responses, most participants were experienced attending physicians (70.93%). To diagnose azoosper-mia definitively, 81.7% requested two semen samples. Commonly ordered hormone tests included serum follicle-stimulating hormone (FSH) (97.0%), total testosterone (92.9%), and luteinizing hormone (86.9%). Genetic testing was requested by 66.6%, with karyotype analysis (86.2%) and Y chromosome microdeletions (88.3%) prevalent. Diagnostic testicular biopsy, distinguishing obstructive azoospermia (OA) from NOA, was not performed by 45.1%, while 34.6% did it selectively. Differ-entiation relied on physical examination (76.1%), serum hormone profiles (69.6%), and semen tests (68.1%). Expectations of finding sperm surgically were higher in men with normal FSH, larger testes, and a history of sperm in ejaculate. Conclusions:Conclusions: This expert survey, encompassing 367 participants from 49 countries, unveils congruence with recommended guidelines in NOA diagnosis. However, noteworthy disparities in practices suggest a need for evidence-based, international consensus guidelines to standardize NOA evaluation, addressing existing gaps in professional recommendations.

Published
2024
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8. Lunapark deficiency leads to an autosomal recessive neurodevelopmental phenotype with a degenerative course, epilepsy and distinct brain anomalies

Author

Accogli, Andrea, Zaki, Maha S, Al-Owain, Mohammed, Otaif, Mansour Y, Jackson, Adam, Argilli, Emanuela, Chandler, Kate E, De Goede, Christian GEL, Cora, Tülün, Alvi, Javeria Raza, Eslahi, Atieh, Asl Mohajeri, Mahsa Sadat, Ashtiani, Setareh, Au, PY Billie, Scocchia, Alicia, Alakurtti, Kirsi, Pagnamenta, Alistair T, Toosi, Mehran Beiraghi, Ghayoor Karimiani, Ehsan, Mojarrad, Majid, Arab, Fatemeh, Duymuş, Fahrettin, Scantlebury, Morris H, Yeşil, Gözde, Rosenfeld, Jill Anne, Türkyılmaz, Ayberk, Sağer, Safiye Güneş, Sultan, Tipu, Ashrafzadeh, Farah, Zahra, Tatheer, Rahman, Fatima, Maqbool, Shazia, Abdel-Hamid, Mohamed S, Issa, Mahmoud, Efthymiou, Stephanie, Bauer, Peter, Zifarelli, Giovanni, Salpietro, Vincenzo, Al-Hassnan, Zuhair, Banka, Siddharth, Sherr, Elliot H, Gleeson, Joseph G, Striano, Pasquale, Houlden, Henry, Severino, Mariasavina, and Maroofian, Reza

Subjects
Pediatric, Neurosciences, Genetics, Neurodegenerative, Clinical Research, Congenital Structural Anomalies, Brain Disorders, Rare Diseases, Human Genome, Epilepsy, 2.1 Biological and endogenous factors, Aetiology, Mental health, Neurological, Clinical sciences, Biological psychology
Abstract

Abstract: LNPK encodes a conserved membrane protein that stabilizes the junctions of the tubular endoplasmic reticulum network playing crucial roles in diverse biological functions. Recently, homozygous variants in LNPK were shown to cause a neurodevelopmental disorder (OMIM#618090) in four patients displaying developmental delay, epilepsy, and non-specific brain malformations including corpus callosum hypoplasia and variable impairment of cerebellum. We sought to delineate the molecular and phenotypic spectrum of LNPK-related disorder. Exome or genome sequencing was carried out in eleven families. Thorough clinical and neuroradiological evaluation was performed for all the affected individuals, including review of previously reported patients. We identified twelve distinct homozygous loss-of-function variants in sixteen individuals presenting with moderate to profound developmental delay, cognitive impairment, regression, refractory epilepsy and a recognizable neuroimaging pattern consisting of corpus callosum hypoplasia and signal alterations of the forceps minor (“ear-of-the-lynx” sign), variably associated with substantia nigra signal alterations, mild brain atrophy, short midbrain, and cerebellar hypoplasia/atrophy. In summary, we define the core phenotype of LNPK-related disorder and expand the list of neurological disorders presenting with the “ear of the lynx” sign suggesting a possible common underlying mechanism related to endoplasmic reticulum-phagy dysfunction.

Published
2023

11. Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans.

Author

Guo, Long, Salian, Smrithi, Xue, Jing-Yi, Rath, Nicola, Rousseau, Justine, Kim, Hyunyun, Ehresmann, Sophie, Moosa, Shahida, Nakagawa, Norio, Kuroda, Hiroshi, Clayton-Smith, Jill, Wang, Juan, Wang, Zheng, Banka, Siddharth, Jackson, Adam, Zhang, Yan-Min, Wei, Zhen-Jie, Hüning, Irina, Brunet, Theresa, Ohashi, Hirofumi, Thomas, Molly, Bupp, Caleb, Miyake, Noriko, Matsumoto, Naomichi, Mendoza-Londono, Roberto, Costain, Gregory, Hahn, Gabriele, Di Donato, Nataliya, Yigit, Gökhan, Yamada, Takahiro, Nishimura, Gen, Ansel, Karl, Wollnik, Bernd, Hrabě de Angelis, Martin, Mégarbané, André, Rosenfeld, Jill, Heissmeyer, Vigo, Ikegawa, Shiro, and Campeau, Philippe

Subjects
ERI1, exoribonuclease, ribosomopathy, short stature, skeletal dysplasia, spondyloepimetaphyseal dysplasia, Humans, Exoribonucleases, Histones, Mutation, Missense, RNA, Ribosomal, 5.8S, RNA, RNA, Messenger
Abstract

ERI1 is a 3-to-5 exoribonuclease involved in RNA metabolic pathways including 5.8S rRNA processing and turnover of histone mRNAs. Its biological and medical significance remain unclear. Here, we uncover a phenotypic dichotomy associated with bi-allelic ERI1 variants by reporting eight affected individuals from seven unrelated families. A severe spondyloepimetaphyseal dysplasia (SEMD) was identified in five affected individuals with missense variants but not in those with bi-allelic null variants, who showed mild intellectual disability and digital anomalies. The ERI1 missense variants cause a loss of the exoribonuclease activity, leading to defective trimming of the 5.8S rRNA 3 end and a decreased degradation of replication-dependent histone mRNAs. Affected-individual-derived induced pluripotent stem cells (iPSCs) showed impaired in vitro chondrogenesis with downregulation of genes regulating skeletal patterning. Our study establishes an entity previously unreported in OMIM and provides a model showing a more severe effect of missense alleles than null alleles within recessive genotypes, suggesting a key role of ERI1-mediated RNA metabolism in human skeletal patterning and chondrogenesis.

Published
2023

12. Structures, processes and outcomes between first referral and referral hospitals in low-income and middle-income countries: a secondary preplanned analysis of the FALCON and ChEETAh randomised trials

Author

Rajeev Sharma, Neha Mishra, Simon Cousens, Sanjay Gupta, Thomas Pinkney, Neil Smart, Jonathan Cook, David Jayne, Hemanth Kumar, Peter Brocklehurst, Mohammed Bashir, Dmitri Nepogodiev, Adesoji O Ademuyiwa, Philip Alexander, Laura Magill, Mark Monahan, Rachel Moore, Stephen Tabiri, Joseph Yorke, Dion Morton, Aneel Bhangu, Bryar Kadir, Naveen Sharma, Punam Mistry, Joshua Arthur, Muneer A Malik, Tracy Roberts, Elisee Rwagahirima, Christian Urimubabo, Ewen Harrison, Vijay Kumar, Julia Brown, Pollyanna Hardy, Amit Mahajan, Pratik Solanki, James Glasbey, Himani Gupta, Omar Omar, Joana Simoes, Sivesh K Kamarajah, Adesoji Ademuyiwa, Felix Alakaloko, Olumide Elebute, Omolara Faboya, Justina Seyi-Olajide, Anita Thomas, David Lissauer, Zainab Imam, George Ihediwa, Zainab O Imam, Felix M Alakaloko, Pradeep Zechariah, Suraj Surendran, Olatunji O Lawal, Mohammed Adnan, Savleen Kaur, Faustin Ntirenganya, JC Allen Ingabire, Lawani Ismaïl, Emmy Runigamugabo, Djifid Morel Seto, Paul Wondoh, Charles Dally, Kwabena Agbedinu, Florence Dedey, Enoch Tackie, Frank Enoch Gyamfi, Anthony Davor, Akinlabi Ajao, Omobolaji Ayandipo, Olalekan Ajai, Mobolaji Oludara, Muhammad Daniyan, Danjuma Sale, Lawal Abdullahi, Olabisi Osagie, Adedeji Fatuga, Muzzammil Abdullahi, Manish Pathak, Prashant Singh, Rita Jain, Kwaku Boakye-Yiadom, Kazeem Atobatele, Ayokunle Ogunyemi, Olabode Oshodi, Christopher Bode, Omobolaji O Ayandipo, Akinlabi E Ajao, Godwin Akaba, Gabriella Hyman, Deepak Singh, Olukemi Akande, Sivesh Kathir Kamarajah, Naseem Akhtar, José A Flores, Donna Smith, Olatunji Lawal, Hadijat Olaide Raji, Zafar Khan, Matthew Francis, Emmanuel Williams, Pardeep Kumar, Oliver Samuel, María Paz Muñoz, Arun Chaturvedi, Sameer Gupta, Puneet Prakash, John Raphael, Funmilola Wuraola, Olalekan Olasehinde, Murlidhar V Pai, Deepak Jain, Anwar Sadat Seidu, Victor Ifeanyichukwu Modekwe, Jideofor Okechukwu Ugwu, Lukmon Amosu, Akan Inyang, Michael Amoah, Boateng Nimako, Dhruva Ghosh, Neil Winkles, Olabisi O Osagie, Karolin Kroese, Olubunmi Ogein, Mustapha Yakubu, Vasanth Mark Samuel, Cecil Thomas, Enono Yhoshu, Vishal Michael, William Bhatti, Swati Daniel, Jyoti Dhiman, Atul Suroy, Christopher O Bode, George C Ihediwa, Adaiah Soibi-Harry, Benedetto Osunwusi, Elizabeth Li, Sonia Mathai, Deepak Singla, Farhanul Huda, Aisha Mustapha, Anisah Yahya, Samuel Mensah, Puneet Pareek, Bernard Ofori, Souliath Lawani, Oluwafunmilayo Adeniyi, Opeyemi Rebecca Akinajo, Richard Ofosu-Akromah, Olumide Adeniyi, Adewale O. Adisa, Natacha Boumas, Fareeda Galley, Frank Enoch Gyamfi Parvez D Haque, Antonio Ramos de la Medina, Chukwuma Okereke, Ronald Tubasime, Felicity Brant, Sohini Chakrabortee, Parvez D Haque, Emily Heritage, Carmela Lapitan, Rachel Lillywhite, Pierre Sodonougbo, Pamphile Assouto, Michel Fiogbe, Houenoukpo Koco, Serge Metchinhoungbe, Hodonou Sogbo, Hulrich Behanzin, Yannick Tandje, Sosthène Kangni, Cyrile Kpangon, Marcelin Akpla, Hugues Herve Chobli, Blaise Kovohouande, Gérard Agboton, Rene Ahossi, Raoul Baderha Ngabo, Nathan Bisimwa, Covalic Melic Bokossa Kandokponou, Mireille Dokponou, Francis Moïse Dossou, Corinne Dzemta, Antoine Gaou, Roland Goudou, Emmanuel Hedefoun, Sunday Houtoukpe, Felix Kamga, Eric Kiki- Migan, Ismaïl Lawani, René Loko, Afissatou Moutaïrou, Pencome Ogouyemi, Fouad Soumanou, Pia Tamadaho, Mack-Arthur Zounon, Luke Aniakwo Adagrah, Bin Baaba Alhaji Alhassan, Mabel Pokuah Amoako-Boateng, Anthony Baffour Appiah, Alvin Asante-Asamani, Benedict Boakye, Samuel A Debrah, Donald Enti, Rahman Adebisi Ganiyu, Patience Koggoh, Richard Kpankpari, Isabella Naa M. Opandoh, Meshach Agyemang Manu, Maison Patrick Opoku Manu, Martin Tangnaa Morna, John Nkrumah, Michael Nortey, Emmanuel Owusu Ofori, Elizaberth Mercy Quartson, Esther Adjei-Acquah, Eric Agyemang Vera Agyekum, Rebecca Adjeibah Akesseh, Forster Amponsah-Manu, Ato Oppong Acquah, Leslie Issa Adam-Zakariah, Esther Asabre, Ruby Acheampong Boateng, Barbara Koomson, Ataa Kusiwaa, Emmanuel Yaw Twerefour, James Ankomah, Frank Assah-Adjei, Anthony Appiah Boakye, Godfred Fosu, Godwin Serbeh, Kofi Yeboah Gyan, Isaac Omane Nyarko, Zelda Robertson, Ralph Armah, Christopher Asare, Delali Akosua Gakpetor, Victoria Sena Gawu, Ambe Obbeng, Doris Ofosuhene, Dorcas Osei-Poku, Diana Puozaa, Arkorful Ebenezer Temitope, Regina Acquah, James Amoako, Akosua Dwamena Appiah, Mark Aseti, Charles Banka, Samuel Dadzie, Derick Essien, Romeo Hussey, Jemima Kwarteng, Naa Anyekaa Sowah, Grace Yeboah, Cynthia Yeboah, Kwame Gyambibi Addo, Enoch Appiah Akosa, Percy Boakye, Christian Larbi Coompson, Brian Gyamfi, Bismark Effah Kontor, Christian Kyeremeh, Ruth Manu, Elijah Mensah, Friko Ibrahim Solae, Gideon Kwasi Toffah, Dorcas Otuo Acheampong, Jane Acquaye, Michael Adinku, Anita Eseenam Agbeko, Emmanuel Gyimah Amankwa, George Amoah, Juliana Appiah, Alex Ayim, Emmanuel Kafui Ayodeji, Jonathan Boakye-Yiadom, Edward Amoah Boateng, Christian Kofi Gyasi-Sarpong, Naabo Nuhu Noel Hamidu, Iddrisu Haruna, Naa Kwarley, Agbenya Kobla Lovi, Bertina Beauty Nyadu, Dominic Opoku, Anita Osabutey, Robert Sagoe, Samuel Tuffour, Yaa Tufour, Francis Akwaw Yamoah, Abiboye Cheduko Yefieye, Nii Armah Adu-Aryee, Faisal Adjei, Erica Akoto, Elikem Ametefe, Joachim Kwaku Amoako, Godsway Solomon Attepor, George Darko Brown, Benjamin Fenu, Philemon Kwame Kumassah, David Olatayo Olayiwola, Theodore Wordui, Nelson Agboadoh, Fatao Abubakari, Cletus Ballu, Charles Gyamfi Barimah, Guy Casskey Boateng, Prosper Tonwisi Luri, Abraham Titigah, Frank Owusu, Raphael Adu-Brobbey, Abdul-Hamid Labaran, Junior Atta Owusu, Vivian Adobea, Amos Bennin, Fred Dankwah, Stanley Doe, Ruth Sarfo Kantanka, Ephraim Kobby, Kennedy Kofi Korankye Hanson Larnyor, Edwin Osei, Prince Yeboah Owusu, Clement Ayum Sie-Broni, Marshall Zume, Francis Atindaana Abantanga, Darling Ramatu Abdulai, Daniel Kwesi Acquah, Emmanuel Ayingayure, Imoro Osman, Sheba Kunfah, Gbana Limann, Shamudeen Alhassan Mohammed, Sheriff Mohammed, Yakubu Musah, Emmanuel Abem Owusu, Abdul-Hafiz Saba, Edwin Mwintiereh Ta-ang Yenli, Arun Gautham, Alice Hepzibah, Grace Mary, Dimple Bhatti, Karan Bir, Tapasya Dhar, Sunita Goyal, Goyal Ankush, Monika Hans, Parvez Haque, Samuel Konda, Anil Luther, Shalini Makkar, Kavita Mandrelle, Partho Mukherjee, Reuben Rajappa, Ravinder Thind, Alen Thomas, Arti Tuli, Sreejith Veetil, Esther Daniel Mark Jesudason, K Priyadarshini, Latha Madankumar, Rohin Mittal, Ida Nagomy, Rajesh Selvakumar, Bharat Shankar, Moonish Sivakumar, Rajeevan Sridhar, Devabalan Titus, Manisha Aggarwal, Parth Dhamija, Vinoth Kanna, Ashwani Kumar, Gurtaj Singh, Josy Thomas, Amos Dasari, Priya Jacob, Elizabeth Kurien, Arpit Mathew, Danita Prakash, Anju Susan, Rose Varghese, Rahul Alpheus, Ashish Choudhrie, Nitin Peters, Subrat Raul, Rakesh Vakil, Wenceslao Ángeles Bueno, Francisco Barbosa Camacho, Aldo Bernal Hernández, Ana Bogurin Arellano, Edgar Cortes Torres, Clotilde Fuentes Orozco, Erick González García de Rojas, Alejandro González Ojeda, Bertha Guzmán Ramírez, Michel Hernández Valadez, Diego Luna Acevedo, Rubén Morán Galaviz, Oscar Olvera Flores, José Pérez Navarro, Kevin Pintor Belmontes, Fernando Ramirez Marbello, Luis Ramírez-González, Laura Reyes Aguirre, Ramona Rojas García, Eduardo Valtierra Robles, Reyes Cervantes Ortiz, Gonzalo Hernandez Gonzalez, Rosa Hernandez Krauss, Luis Hernández Miguelena, Marco Hurtado Romero, Isaac Baltazar Gomez, Celina Cuellar Aguirre, Alejandro Cuevas Avendaño, Luis Dominguez Sansores, Hector Ortiz Mejia, Laura Urdapilleta Gomez del Campo, Claudia Caballero Cerdan, David Dominguez Solano, Rafael Toriz Garcia, Mariana Barreto Gallo, Ana Cortes Flores, Alejandro Gonzalez Ojeda, Monica Jimenez Velasco, Rozana Reyes Gamez, Roque Lincona Menindez, Alberto Navarrete Peón, Irani Durán Sánchez, Diana Gonzalez Vazquez, Maria Martínez Lara, Laura Martinez Perez Maldonado, Alejandra Nayen Sainz de la Fuente, Antonio Ramos De la Medina, Khadija Ado, Mohammed Aliyu, Lofty-John Anyanwu, Mahmoud Magashi, Abubakar Muhammad, Saminu Muhammad, Bello Muideen, Idris Takai, Onyekachi Ukata, Opeoluwa Adesanya, David Awonuga, Olushola Fasiku, Chidiebere Ogo, Moruf Abdulsalam, Abimbola Adeniran, Grace Eke, Esther Momson, Francisca Nwaenyi, Olufunmilade Omisanjo, Yusuf Oshodi, Yemisi Oyewole, Omotade Salami, Omolara Williams, Victoria Adeleye, Opeyemi Akinajo, David Akinboyewa, Iyabo Alasi, Oluwole Atoyebi, Olanrewaju Balogun, Orimisan Belie, Andrew Ekwesianya, Francis Ezenwankwo, Adesola Jimoh, Jubril Kuku, Oluwaseun Ladipo- Ajayi, Ayomide Makanjuola, Olayanju Mokwenyei, Samuel Nwokocha, Rufus Ojewola, Abraham Oladimeji, Thomas Olajide, Oluwaseun Oluseye, Aloy Ugwu, Ochomma Egwuonwu, Okechukwu Ekwunife, Victor Modekwe, Chukwuemeka Okoro, Chisom Uche, Kenneth Ugwuanyi, Chuka Ugwunne, Akeem Adeleke, Wilson Adenikinju, Akinfolarin Adepiti, Adewale Aderounmu, Abdulhafiz Adesunkanmi, Adewale Adisa, Samuel Ajekwu, Olusegun Ajenjfuja, Jerrie Akindojutimi, Akinbolaji Akinkuolie, Olusegun Alatise, Olubukola Allen, Micheal Archibong, Olukayode Arowolo, Deborah Ayantona, Ademola Ayinde, Olusegun Badejoko, Tajudeen Badmus, Amarachukwu Etonyeaku, Emeka Igbodike, Omotade Ijarotimi, Adedayo Lawal, Fayowole Nana, Tunde Oduanafolabi, Olaniyi Olayemi, Stephen Omitinde, Owolabi Oni, Chigozie Onyeze, Ernest Orji, Adewale Rotimi, Abdulkadir Salako, Olufemi Solaja, Oluwaseun Sowemimo, Ademola Talabi, Mohammed Tajudeen, Francis Adebayo, Oseremen Aisuodionoe- Shadrach, Lazarus Ameh, Ndubuisi Mbajiekwe, Felix Ogbo, Samson Olori, Samuel Sani Abu Sadiq, Nancy Tabuanu, Martins Uanikhoba, Godwin Chiejina, Ekpo Edet, Mary Isa, Faith Iseh, Adams Marwa, Sunday Ogbeche, Edima Olory, Gabriel Udie, Joseph Udosen, Usang Usang, Olukayode Abayomi, Rukiyat Abdus-Salam, Sikiru Adebayo, Olanrewaju Amusat, Kelvin Egbuchulem, Hyginus Ekwuazi, Peter Elemile, Taiwo Lawal, Solomon Olagunju, Peter Osuala, Bamidele Suleman, Augustine Takure, Lukman Abdur-Rahman, Nurudeen Adeleke, Muideen Adesola, Rafiat Afolabi, Sulaiman Agodirin, Isiaka Aremu, Jibril Bello, Saheed Lawal, Abdulwahab Lawal, Hadijat Raji, Olayinka Sayomi, Asimiyu Shittu, Jude Ede, Sebastian Ekenze, Vincent Enemuo, Matthew Eze, Uchechukwu Ezomike, Emmanuel Izuka, Okezie Mbadiwe, Ngozi Mbah, Uba Ezinne, Iweha Ikechukwu, Okoi Nnyonno, Philemon Okoro, Igwe Patrick, Oriji Vaduneme, Abhulimen Victor, Salathiel Kanyarukiko, Francine Mukaneza, Deborah Mukantibaziyaremye, Aphrodis Munyaneza, Gibert Ndegamiye, Ronald Tubasiime, Moses Dusabe, Emelyne Izabiriza, Hope Lydia Maniraguha, Christophe Mpirimbanyi, Josiane Mutuyimana, Olivier Mwenedata, Francine Uwizeyimana, Job Zirikana, Aime Dieudonne Hirwa, Elysee Kabanda, Salomee Mbonimpaye, Christine Mukakomite, Piolette Muroruhirwe, Georges Bucyibaruta, Gisele Juru Bunogerane, Sosthene Habumuremyi, Jean de Dieu Haragirimana, Alphonsine Imanishimwe, Violette Mukanyange, Emmanuel Munyaneza, Emmanuel Mutabazi, Isaie Ncogoza, Jeannette Nyirahabimana, Mary Augusta Adams, Richard Crawford, Chikwendu Jeffrey Ede, Maria Fourtounas, Morapedi Kwati, Mpho Nosipho Mathe, Ncamsile Anthea Nhlabathi, Hlengiwe Samkelisiwe Nxumalo, Paddy Pattinson, Nnosa Sentholang, Mmule Evelyn Sethoana, Maria Elizabeth Stassen, Laura Thornley, Cheryl Birtles, Mathete Ivy, Cynthia Mbavhalelo, Zain Ally, Abdus-sami Adewunmi, Maria Picciochi, Michael Bahrami-Hessari, Didier Ahogni Benin, Aristide Ahounou, K. Alassan Boukari, Oswald Gbehade, Thierry K Hessou, Sinama Nindopa, M.J. Bienvenue Nontonwanou, Nafissatou Orou Guessou, Arouna Sambo, Sorekou Victoire Tchati, Affisatou Tchogo, Semevo Romaric Tobome, Parfait Yanto, Isidore Gandaho, Armel Hadonou, Simplice Hinvo, Montcho Adrien Hodonou, Sambo Bio Tamou, Marie-Claire Kouroumta, Enrif Malade, Anne stredy Mkoh Dikao, Joel Nzuwa Nsilu, Nathan Bisimwa Mitima, Cyrille Kpangon, Stephane Laurent Loupeda, Mamonde Victorin Agbangla, Sena Emmanuel Hedefoun, Thierry Mavoha, Juvenal Ngaguene, Janvier Rugendabanga, Rish Romaric Soton, Martin Totin, Mouhamed Agbadebo, Irene Akpo, Hubert Dewamon, Martin Djeto, Aissatou Hada, Monsede Hollo, Albert Houndji, Anasthasie Houndote, Sylvestre Hounsa, Expedit Kpatchassou, Hugues Yome, Mohamed Moussa Alidou, Bonheur Dossou Yovo, Robert Guinnou, Souleymane Hamadou, Nabil Moussa, Boniface Cakpo, Lolyta Etchisse, Emery Hatangimana, Moise Muhindo, Katia Sanni, Agossou Barthelemy Yevide, Hermann Agossou, Fiston Basirwa Musengo, Bill Armstrong Alia, Arnaud Alitonou, Lucien Agbanda, Julien Attinon, Marcel Gbassi, Nounagnon Rene Hounsou, Derick Esssien, Yakubu Mustapha, Kojo Nunoo-Ghartey, Luke A Aniakwo, Margarey N M Adjei, Yvonne Adofo-Asamoah, Meshach M Agyapong, Thomas Agyen, Baba A B Alhassan, Mabel P Amoako-Boateng, Josephine Ashong, Joseph K Awindaogo, Benjamin B Brimpong, Makafui S C J K Dayie, Wendy W Ghansah, Jude E Gyamfi, Vincent Kudoh, Philip Mensah, Isabella N Morkor Opandoh, Martin T Morna, Emelia Odame, Emmanuel O Ofori, Sandra Quaicoo, Elizabert M Quartson, Cynthia Teye-Topey, Makafui Yigah, Safia Yussif, Vera O Agyekum-Gyimah, Eric Agyemang, Arko Akoto- Ampaw, Temitope E Arkorful, Moses A Dokurugu, Nanabanyin Essel, Aja Ijeoma, Emmanuel L Obiri, Karen N D Quarchey, Leslie Adam-Zakariah, Aaron B Andoh, Ruby A Boateng, Atta Kusiwaa, Adeline Naah, Ato Oppon-Acquah, Benjamin A Oppong, Emma A Agbowada, Ameley Akosua, O Lawrence Dorcas Acheampong, Frank E Gyamfi, Bertina B Nyadu, Samira Abdulai, Nii A Adu-Aryee, Joachim K Amoako, Nicholas T Aperkor, Wilfred K Asman, Godsway S Attepor, Antoinette A Bediako-Bowan, George D Brown, Victor K Etwire, Benjamin S Fenu, Philemon K Kumassah, Linda A Larbi-Siaw, Josephine Nsaful, David O Olatola, Sandra E Tsatsu, Iddrisu I A Abdul-Aziz, Johnson Akunyam, Gilbert A G Anasara, Charles G Barimah, Guy C Boateng, Ponala W Kwabena, Seidu M Kwarteng, Prosper T Luri, Kennedy Ngaaso, David K D Ogudi, Collins Kyeremeh, Clement Sie-Broni, Saba Abdul-Hafiz, Daniel K Acquah, Shamsudeen M Adams, Mohammed S Alhassan, Munira Amadu, Samuel A Asirifi, Martin Awe, Millicent Azanlerigu, Mathias K Dery, Yenli Edwin, Abantanga Atindaana Francis, Aloysius Maalekuu, Hawa Malechi, Ibrahim Mohammed, Kareem Mumuni, Bernard A Ofori, Jonathan I K Quansah, Napoleon Bellua Sam, Anwar S Seidu, Shekira Yahaya, Emmanuel Kojo Acquah, Jaabir Alhassan, Christian L Coompson, Addo K Gyambibi, Ametepe Jeffery-Felix, Bismark E Kontor, Gifty Naah, Carmen Noufuentes, Abraham Sakyi, Ramkaran Chaudhary, Sanjeev Misra, Dharma R Poonia, Kirti K Rathod, Mahaveer S Rodha, Nivedita Sharma, Subhash C Soni, Vaibhav K Varsheney, Jeevan R Vishnoi, Deepak K Garnaik, Manoj J Lokavarapu, Rohit Ranjan, Rajkumar K Seenivasagam, Shanky Singh, Raunak Verma, Suzan John, Jeffery A Kalyanapu, Ananta Kutma, Sanish Philips, Arun K Gautham, Deepak S Singh, Eunice S Abraham, Chetana Chetana, Prashant Dummala, Chinta S Gold, Jurgen Jacob, Jeremiah N Joseph, Elizabeth N Kurien, Priya Mary, Arpit J Mathew, Amy E Mathew, Danita D Prakash, Ashwin Sukumar, Niyah Syam, Alisha Bhatt, Dhruva N Ghosh, Ankush Goyal, Monika A Hans, Jyoti Jyoti, Karan Kumar, Vivin Daniel Sam, Ravinder Singh Thind, Sreejith K Veetil, Rahul Williams, D Sreekar, Esther R Daniel, Smitha E Jacob, Mark R Jesudason, Pushplatha Kumari, Soosan Prasad, Srujan Sharma, Moonish V Sivakumar, Paul Trinity, Sudheer Kanchodu, K Leshiini, Sundeep S Saluja, Ashok K Attri, Ishan Bansal, Monika Gureh, Simran Kapoor, Harmanjot Kaur, Simrandeep Singh, Viju John, Nivesh Agrawal, Uttkarsh Kumar, S Abhishek, Vikram Sehrawat, Gaurav Thami, Stanley Mathew, P S Prabhu, P T Sundeep, Shiv Rajan, Mohit Singh, Abhilasha Tripathi, Philip V Alexander, A Vijay, Moloti Kichu* Ismavel, Carolin V Solomi, Rahul A Alpheus, Ashish Victor Choudhrie, Rashmi Jacob Gunny, Susan Joseph, Nitin J Peters, Neha Pundir, Ram Samujh, Hafsa I Ahmed, Gowhar Aziz, Nisar A Chowdri, Rayees A Dar, Robindera Kour, Imtiyaz Mantoo, Asif Mehraj, Fazl Q Parray, Najmus Saqib, Zamir A Shah, Rauf A Wani, Komal Rautela, Nishu Singh, Priyanka Chowdhury, Sona Chowdhury, Pragyanmai Nayak, Bipradas Roy, Andrea S Alvarez Villaseñor, Kriscia V Ascencio Díaz, Victor J Avalos Herrera, Francisco J Barbosa, Elyoenai Bonilla Ahumada, Irma V Brancaccio, Miguel A Calderón, Guadalupe Castillo Cardiel, Guillermo A Cervantes, Gabino Cervantes Guevara, Enrique Cervantes Perez, Maria Chávez, Jonathan M Chejfec, Luis R Cifuentes, Ana O Cortés, Edgar J Cortes, Tania A Cueto, Andrea E Cueto, Esteban Cueva Martinez, Paulina Domínguez Barradas, Isaac Esparza Estrada, Paola Flores Becerril, Luis A García, Benjamín García Reyna, Eduardo Gómez Sánchez, Jaime L González, Eduardo González Espinoza, Fanny Y González, Cristhian S Guerrero, José A Guzmán, Bertha G Guzmán, Mario J Guzmán, DanielA Hérnandez Alva, SilviaA Ibarra Camargo, JuanC Ibarrola Peña, Martin Islas Torres, Jorge Jiménez Tornero, ZayraM Lara Pérez, Roberto Mares País, MelP Mellado Tellez, RobertoC Miranda Ackerman, Damián Mora Santana, Gilberto Morgan Villela, Rodrigo Nájar Hinojosa, Cesar Nuño Escobar, Itzel Ochoa Rodríguez, Angelica Ortega Barreiro, Jacqueline Osuna Rubio, Luis RPacheco Vallejo, VíctorH Pérez Bocanegra, JoseV Pérez Navarro, Francisco JPlascencia Posada, MaríaA Quirarte Hernández, LuisR Ramirez Gonzalez, Emilio AReyes Elizalde, EveliaV Romo Ascencio, Cornelio Ruelas Bravo, CarlosB Ruiz Velasco, JoséA Sánchez Martínez, Guillermo Sanchez Villaseñor, JoséI Sandoval Pulido, AlejandroG Serrano García, LuisO Suárez Carreón, JuanJ Tijerina 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Trejo-Avila, Roland Kevin CethorthFonseca, Edgard Efren LozadaHernandez, Bruno Crocco Quiros, JairoArturo Rodriguez Ramirez, Gabriela Ambriz-González, MitziR Becerra Moscoso, Ishtar Cabrera-Lozano, AnaB Calderón-Alvarado, FranciscoJ León-Frutos, ErickE Villanueva-Martínez, Aisha Abdullahi, Maimuna Abubakar, MohammedS Aliyu, Mudi Awaisu, Fadimatu Bakari, Abigail Olajumoke Balogun, Ahmad Bello, Kehinde Michael Duromola, Stephen G Gana, Mukoro Duke George, Justina Gimba, Isaac Gundu, Lambert Onahi Iji, Aminat O Jimoh, Afolabi K Koledade, Ahmad T Lawal, Bilkisu K Lawal, Stanley Emeka Nwabuoku, Oluseyi O Ogunsua, Ifeanyi Fidelis Okafor, Ethos Ike Okorie, Nasir Oyelowo, Ibrahim A Saidu, Tunde T Sholadoye, Ibrahim Sufyan, Musliu Adetola Tolani, Aliyu Muhammad Tukur, Ahmad Shehu Umar, Aminatu M Umar, Hajara Umaru-Sule, Mohammed Usman, Alfa Yakubu, Salisu Abeku Yusuf, Abdulhafiz A Abdulkarim, Lawal Barau Abdullahi, Khadija A Ado, Nura U Aliyu, Lofty-John Chukwuemeka Anyanwu, Sulaiman M Daneji, Mahmoud Kawu Magashi, Mohammad A Mohammad, Abubakar Bala Muhammad, Saminu S Muhammad, Bello Abodunde Muideen, Calistus U Nwachukwu, Suleiman B Sallau, Abdulrahman A Sheshe, Abdulmajeed Soladoye, Idris Usman Takai, Garzali I Umar, Abubakar Yahaya, Lubabatu Abdulrasheed, Joel A Adze, Lydia R Airede, Bashiru Aminu, Stephen B Bature, Firdaws Bello-Tukur, Damai Chinyio, SharonA N Duniya, Moses C Galadima, Babatunde K Hamza, Samaila Joshua, Stephen A Kache, Williams Y Kagomi, Ifeanyi A Kene, Jamila Lawal, Jerry G Makama, Caleb Mohammed, Amina A Mohammed-Durosinlorun, Deborah Nuwam, Abdulrasheed Sani, Salome Tabara, Mathew C Taingson, Emmanuel Usam, Josiah Yakubu, Folasade Adegoke, Oluwasuyi Ige, Tunde A Odunafolabi, Chukwuma E Okereke, Oluwafemi O Oladele, Oluwaseun H Olaleye, Oyetunde O Olubayo, Olukayode P Abiola, Henry O Abiyere, Idowu O Adebara, GbadeboT C Adeleye, Adebayo A Adeniyi, Olumide E Adewara, Olabisi T Adeyemo, Ademola A Adeyeye, Abimbola L Ariyibi, Babatunde S Awoyinka, Olumide M Ayankunle, Olakunle F Babalola, Adewumi Bakare, TajudeenI B Bakare, Oluseyi O Banjo, Peter A Egharevba, Oluwafemi S Fatudimu, John A Obateru, Oluremi J Odesanya, Owolabi D Ojo, Abiodun I Okunlola, Cecilia K Okunlola, Adewale T Olajide, Tesleem O Orewole, Adedayo I Salawu, Moruf A Abdulsalam, Aderinsola T Adelaja, Olalekan T Ajai, Noble Anyanwu, Kazeem M Atobatele, Oludayo Oluwaseyi Bakare, Omolara M Faboya, Francisca C Nwaenyi, Ayokunle A Ogunyemi, Mobolaji A Oludara, Olufunmilade A Omisanjo, Chinonso U Onyeka, Olabode A Oshodi, Yusuf A Oshodi, Omotade S Salami, Omolara M Williams, Esther Abunimye, Adebunmi Adeoluwa, Adedotun Adesiyakan, Victoria Ibukunoluwa Adeyeye, Moses Vincent Agbulu, David O Akinboyewa, Iyabo O Alasi, Michael Amao, Christiana Ashley-Osuzoka, Oluwole A Atoyebi, Olanrewaju S Balogun, Maryam Oluwatobi Busari, Nnamdi Jonathan Duru, Glory Bassey Edet, Olumide A Elebute, Francis Chinonso Ezenwankwo, Adedeji L Fatuga, Christianah Gbenga-Oke, Emmanuel Sylvester Inyang, Adesola I Jimoh, Jubril Oladayo Kuku, OluwaseunA Ladipo-Ajayi, Abdulrazzaq O Lawal, Christian Chigoze Makwe, Chinelo Victoria Mgbemena, Samuel U Nwokocha, Moses Adebisi Ogunjimi, Ephraim Okwudiri Ohazurike, Rufus W Ojewola, Moyosoluwa Eunice Badedale, Chike J Okeke, Adeyemi A Okunowo, Abraham T Oladimeji, Thomas O Olajide, Olabisi Olanrewaju, Olawunmi Olayioye, Oluwaseun O Oluseye, Stephen Olutola, Kenneth Onyekachi, Adeola Ayoola Orowale, Emili Osariemen, Adedapo Olumide Osinowo, Emmanuel Owie, Christianah Bidemi Oyegbola, Justina OSeyi-Olajide, AdaiahP Soibi-Harry, Manuella Talla Timo, Aloy Okechukwu Ugwu, Emmanuel Ojo Williams, Innocent O Duruewuru, Ochonma A Egwuonwu, Okechukwu Hyginus Ekwunife, James J Emeka, Chimdiebele Daisy Nwosu, Sylvester O Obiechina, Ahuizechukwu E Obiesie, Celestine I Okafor, Theophilus O Okonoboh, Odili A Okoye, Onyekachi A Onu, Chukwudubem C Onyejiaka, Chisom Faith Uche, JosephO Ugboajah, Akeem A Adeleke, Akinfolarin C Adepiti, Adewale A Aderounmu, Abdulhafiz O Adesunkanmi, Adewale O Adisa, Samuel C Ajekwu, Olusegun K Ajenifuja, Olusegun I Alatise, Tajudeen A Badmus, Tajudeen O Mohammed, Abdulkadir A Salako, Oludayo A Sowande, Ademola O Talabi, Funmilola O Wuraola, Paul Aderemi Adegoke, Abidemi Akinloye, Ayodeji Akinniyi, Joseph Ejimogu, Ideyonbe Samuel Eseile, Olakayode Olaolu Ogundoyin, Amos Okedare, Dare Isaac Olulana, Omolara Omotola, Francis Sanwo, Collins C Adumah, Adewale O Ajagbe, Olugbenga P Akintunde, Opeyemi Q Asafa, Kehinde Awodele, Amogu K Eziyi, Adeniyi O Fasanu, Olufemi O Ojewuyi, Abiodun R Ojewuyi, Abisola E Oyedele, Oluwaseun A Taiwo, Habiba I Abdullahi, Nathaniel D Adewole, Teddy E Agida, Eunice E Ailunia, Oseremen Aisuodionoe-Shadrach, Godwin O Akaba, Janet Alfred, Terkaa Atim, Kehinde G Bawa, John Y Chinda, Esther B Daluk, Sefiu B Eniola, Augusta O Ezenwa, Stephen E Garba, Philip M Mshelbwala, Ngozi O Ndukwe, Idoko P Ogolekwu, Alexander A Ohemu, Samuel A Sani, Salisu Suleiman, Helen Sunday, Nancy O Tabuanu, Aminu M Umar, Peter I Agbonrofo, Alexander I Arekhandia, Morrison E Edena, Raymond A Eghonghon, Joel E Enaholo, Genesis Ida, Stanley N Ideh, Oseihie I Iribhogbe, Omorodion O Irowa, Maradona E Isikhuemen, Oluwatomi R Odutola, Kester O Okoduwa, Scott O Omorogbe, David Oruade, Osasumwen T Osagie, Osarenkhoe Osemwegie, RukiyatA Abdus-Salam, Sikiru Adekola Adebayo, Oluwasanmi A Ajagbe, Gboyega Ajibola, Kelvin I Egbuchulem, Hyginus O Ekwuazi, Adegbolahan Fakoya, Oluwasegun C Idowu, David O Irabor, Taiwo A Lawal, Olakayode O Ogundoyin, Oluwabukade Ojediran, Naomi Olagunju, Akinsola T Sanusi, Augustine O Takure, Lukman Olajide Abdur-Rahman, Mary Oluwadamilola Adebisi, Nurudeen Abiola Adeleke, Rafiat Tinuola Afolabi, Isiaka Ishola Aremu, Jibril Oyekunle Bello, Robiat Bello, Saheed Abolade Lawal, Adeolu Ojajuni, Sabur Oyewale, Victor Abhulimen, Patrick O Igwe, Ikechukwu Enyinnaya Iweha, Raphael E John, Nnyonno Okoi, Philemon E Okoro, Vaduneme Kingsley Oriji, Ibiene T Oweredaba, Japhet Mizero, Immaculee Mutimamwiza, Francoise Nirere, Irenee Niyongombwa, Jean Paul Majyabere, Anastase Byaruhanga, Rongin Dukuzimana, Jean Aimable Habiyakare, Marie Gloriose Nabada, Marcel Uwizeye, Mathias Ruhosha, Joselyne Igiraneza, Faustine Ingabire, Aloys Karekezi, Jean pierre Masengesho, Lydia Mukamazera, Clemence Mukangabo, Jean Paul Niyomuremyi, Gabriel Ntwari, Celestin Seneza, Divine Umuhoza, Pierrine Nyirangeri, Jean Claude Uwimana, Isaie Sibomana, Desire Rubanguka, Josine Umuhoza, Roda Uwayezu, Leoncie Uzikwambara, Herbert Butana, Moise Dusabeyezu, Athanasie Mukasine, Jean N Utumatwishima, Mediatrice Batangana, Jeande Dieu Haragirimana, AllenJ C Ingabire, Espoir Mwungura, Dancilla Nyirasebura, Christian Jean Urimubabo, Anaclet Dusabimana, Sam Kanyesigye, Robert Munyaneza, Jean Yves Shyirakera, Aimee Domingo, Philip Munda, Chido Nyatsambo, Victor Ojo, Rudo Pswarayi, and Soeren Laurberg

Subjects
Medicine (General), R5-920, Infectious and parasitic diseases, RC109-216
Published
2024
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13. Menke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles

Author

Sadegheh Haghshenas, Hidde J. Bout, Josephine M. Schijns, Michael A. Levy, Jennifer Kerkhof, Pratibha Bhai, Haley McConkey, Zandra A. Jenkins, Ella M. Williams, Benjamin J. Halliday, Sylvia A. Huisman, Peter Lauffer, Vivian de Waard, Laura Witteveen, Siddharth Banka, Angela F. Brady, Elena Galazzi, Julien van Gils, Anna C.E. Hurst, Frank J. Kaiser, Didier Lacombe, Antonio F. Martinez-Monseny, Patricia Fergelot, Fabíola P. Monteiro, Ilaria Parenti, Luca Persani, Fernando Santos-Simarro, Brittany N. Simpson, Mariëlle Alders, Stephen P. Robertson, Bekim Sadikovic, and Leonie A. Menke

Subjects
Genetics, QH426-470
Published
2024
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15. Change Detection in Remote Sensing SAR Image Using a Ratio-Based Operator

Author

Banka, Vaibhav, Singh, Gursimar, Paul, Sourabh, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Mahapatra, Rajendra Prasad, editor, Peddoju, Sateesh K., editor, Roy, Sudip, editor, and Parwekar, Pritee, editor

Published
2024
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18. ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy.

Author

Mattison, Kari, Tossing, Gilles, Mulroe, Fred, Simmons, Callum, Butler, Kameryn, Schreiber, Alison, Alsadah, Adnan, Neilson, Derek, Naess, Karin, Wedell, Anna, Wredenberg, Anna, Sorlin, Arthur, McCann, Emma, Burghel, George, Menendez, Beatriz, Hoganson, George, Botto, Lorenzo, Filloux, Francis, Aledo-Serrano, Ángel, Gil-Nagel, Antonio, Tatton-Brown, Katrina, Verbeek, Nienke, van der Zwaag, Bert, Aleck, Kyrieckos, Fazenbaker, Andrew, Balciuniene, Jorune, Dubbs, Holly, Marsh, Eric, Garber, Kathryn, Ek, Jakob, Duno, Morten, Hoei-Hansen, Christina, Deardorff, Matthew, Raca, Gordana, Quindipan, Catherine, van Hirtum-Das, Michele, Breckpot, Jeroen, Hammer, Trine, Møller, Rikke, Whitney, Andrea, Douglas, Andrew, Kharbanda, Mira, Brunetti-Pierri, Nicola, Morleo, Manuela, Nigro, Vincenzo, May, Halie, Tao, James, Sherr, Elliot, Dobyns, William, Baines, Richard, Warwicker, Jim, Parker, J, Banka, Siddharth, Campeau, Philippe, Escayg, Andrew, and Argilli, Emanuela

Subjects
ATP6V0C, V-ATPase, VMA3, epilepsy genetics, neurodevelopmental disorders, Humans, Vacuolar Proton-Translocating ATPases, Saccharomyces cerevisiae, Epilepsy, Adenosine Triphosphate
Abstract

The vacuolar H+-ATPase is an enzymatic complex that functions in an ATP-dependent manner to pump protons across membranes and acidify organelles, thereby creating the proton/pH gradient required for membrane trafficking by several different types of transporters. We describe heterozygous point variants in ATP6V0C, encoding the c-subunit in the membrane bound integral domain of the vacuolar H+-ATPase, in 27 patients with neurodevelopmental abnormalities with or without epilepsy. Corpus callosum hypoplasia and cardiac abnormalities were also present in some patients. In silico modelling suggested that the patient variants interfere with the interactions between the ATP6V0C and ATP6V0A subunits during ATP hydrolysis. Consistent with decreased vacuolar H+-ATPase activity, functional analyses conducted in Saccharomyces cerevisiae revealed reduced LysoSensor fluorescence and reduced growth in media containing varying concentrations of CaCl2. Knockdown of ATP6V0C in Drosophila resulted in increased duration of seizure-like behaviour, and the expression of selected patient variants in Caenorhabditis elegans led to reduced growth, motor dysfunction and reduced lifespan. In summary, this study establishes ATP6V0C as an important disease gene, describes the clinical features of the associated neurodevelopmental disorder and provides insight into disease mechanisms.

Published
2023

20. Evolution of Ion Wake Characteristics with Experimental Conditions

Author

Banka, Rahul, Vermillion, Katrina, Matthews, Lorin, Hyde, Truell, and Couëdel, Lenaïc

Subjects
Physics - Plasma Physics, Physics - Computational Physics
Abstract

Two-dimensional microparticle crystals can be formed in the sheath of a gas discharge plasma. Ions from the bulk plasma are accelerated in the sheath electric field, flowing past the grains to create a positive ion wake downstream from the grains. Interaction between the ion wake and neighboring grains creates additional coupling between oscillation modes and can trigger mode-coupling instability (MCI). Recent experiments have shown that at a fixed discharge power there are threshold pressures above and below which the monolayer always crystallizes or melts, respectively. The melting is due to MCI being triggered in the crystal monolayer, while the crystallization is due to the suppression of MCI by neutral damping in the fluid monolayer. The relationship between the discharge parameters and ion wake characteristics is unknown. A molecular dynamics simulation of ion dynamics and dust charging is used to self-consistently determine the dust charge and ion wake characteristics for different experimental conditions. It is found that the ion wake is strongly dependent on discharge pressure but not affected much by the discharge power.

Published
2022
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21. Correction: Opioid Agonist Maintenance Treatment Outcomes—The OPTIMUS International Consensus Towards Evidence-Based and Patient-Centred Care, an Interim Report

Author

Wiessing, Lucas, Banka-Cullen, Prakashini, Barbaglia, M. Gabriela, Belackova, Vendula, Belbaisi, Saed A. S., Blanken, Peter, Carrieri, Patrizia, Comiskey, Catherine, Dacosta-Sánchez, Daniel, Dom, Geert, Fabricius, Venus, Faria, Hugo, Ignjatova, Liljana, Inić, Nemanja, Jacobsen, Britta, Javakhishvili, Jana D., Kamendy, Zuzana, Kapitány-Fövény, Máté, Kiss, Anna, Kyprianou, Evi, Marchand, Kirsten, Millar, Tim, Mravcik, Viktor, Mustafa, Naser J. Y., Nordt, Carlos, Partanen, Markus, Pedersen, Mads Uffe, Putkonen, Hanna, Razmadze, Mariam, Roux, Perrine, Schulte, Bernd, Seabra, Paulo, Sordo, Luis, Strada, Lisa, Subata, Emilis, Thoma, Esmeralda, Torrens, Marta, Walley, Alexander Y., and Yiasemi, Ioanna

Published
2024
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22. Opioid Agonist Maintenance Treatment Outcomes—The OPTIMUS International Consensus Towards Evidence-Based and Patient-Centred Care, an Interim Report

Author

Wiessing, Lucas, Banka-Cullen, Prakashini, Barbaglia, M. Gabriela, Belackova, Vendula, Belbaisi, Saed A. S., Blanken, Peter, Carrieri, Patrizia, Comiskey, Catherine, Dacosta-Sánchez, Daniel, Dom, Geert, Fabricius, Venus, Faria, Hugo, Ignjatova, Liljana, Inić, Nemanja, Jacobsen, Britta, Javakhishvili, Jana D., Kamendy, Zuzana, Kapitány-Fövény, Máté, Kiss, Anna, Kyprianou, Evi, Marchand, Kirsten, Millar, Tim, Mravcik, Viktor, Mustafa, Naser J. Y., Nordt, Carlos, Partanen, Markus, Pedersen, Mads Uffe, Putkonen, Hanna, Razmadze, Mariam, Roux, Perrine, Schulte, Bernd, Seabra, Paulo, Sordo, Luis, Strada, Lisa, Subata, Emilis, Thoma, Esmeralda, Torrens, Marta, Walley, Alexander Y., and Yiasemi, Ioanna

Published
2023
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23. The Impact of Experience Versus Decision Aids on Patient Preference Toward Virtual Care

Author

Aaron R. Prater, Jack T. McConnell, Nikhil R. Yedulla, Edward L. Peterson, Trevor R. Banka, and Charles S. Day

Subjects
decision aid, education, telehealth, telemedicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

Introduction: Virtual care utilization has increased in recent years bringing questions of how to best inform patients regarding their use. Decision aids (DAs) are tools created to assist patients in making informed decisions about their health care. This study seeks to determine whether a DA or previous experience could better educate and influence patient's preference on virtual care. Methods: One hundred fifty participants from an orthopedic clinic of a multi-hospital system were divided into three groups. Group 1 (Virtual Care Cohort) had at least one previous virtual care visit and was surveyed with the Telemedicine Satisfaction Questionnaire (TSQ). Group 2 (In-person with Decision Aid) and Group 3 (In-person without Decision Aid) had no virtual care experience. Group 2 received a validated virtual care DA with a knowledge test. Both groups were also administered the TSQ. Results: After the DA, patients improved their score on 3 of 4 virtual care knowledge questions. Each cohort demonstrated a positive perception of virtual care; however, the specific reasons for their favorable views varied. The DA cohort did not show increased preference toward virtual care compared with the non-DA group and only responded significantly higher regarding encounter comfort. Patients with previous experience in virtual care responded most favorably to the majority of survey questions regarding their virtual care preferences when compared with both virtual care naive cohorts. Discussion and Conclusion: We found that patient experience was the most important factor in influencing patient preference toward virtual care. Although the DA increased their virtual care knowledge it did not increase their preference; therefore, efforts should be placed at encouraging patient to experience virtual care.

Published
2024
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24. New Strong Gravitational Lenses from the DESI Legacy Imaging Surveys Data Release 9

Author

Storfer, C., Huang, X., Gu, A., Sheu, W., Banka, S., Dey, A., Reyes, J. Inchausti, Jain, A., Kwon, J., Lang, D., Lee, V., Meisner, A., Moustakas, J., Myers, A. D., Tabares-Tarquinio, S., Schlafly, E. F., and Schlegel, D. J.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

We have conducted a search for strong gravitational lensing systems in the Dark Energy Spectroscopic Instrument (DESI) Legacy Imaging Surveys Data Release 9. This is the third paper in a series. These surveys together cover $\sim$19,000 deg$^2$ visible from the Northern Hemisphere, reaching a z-band AB magnitude of $\sim$22.5. We use a deep residual neural network, trained on a compilation of known lensing systems and high-grade candidates as well as nonlenses in the same footprint. After applying our trained neural network to the survey data, we visually inspect and rank images with probabilities above a threshold which has been chosen to balance precision and recall. We have found 1895 lens candidates, of which 1512 are identified for the first time. Combining the discoveries from this work with those from Papers I (335) and II (1210), we have discovered a total of 3057 new candidates in the Legacy Surveys., Comment: Updated final version of manuscript published by the Astronomical Journal, 11 pages, 10 figures, 4 tables. arXiv admin note: text overlap with arXiv:2005.04730

Published
2022
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25. Combined effects of genetic background and diet on mouse metabolism and gene expression

Author

Jordan N. Reed, Faten Hasan, Abhishek Karkar, Dhanush Banka, Jameson Hinkle, Preeti Shastri, Navya Srivastava, Steven C. Scherping, Sarah E. Newkirk, Heather A. Ferris, Bijoy K. Kundu, Sibylle Kranz, Mete Civelek, and Susanna R. Keller

Subjects
Genetics, Transcriptomics, Model organism, Diet, Science
Abstract

Summary: In humans, dietary patterns impact weight and metabolism differentially across individuals. To uncover genetic determinants for differential dietary effects, we subjected four genetically diverse mouse strains to humanized diets (American, Mediterranean, vegetarian, and vegan) with similar macronutrient composition, and performed body weight, metabolic parameter, and RNA-seq analysis. We observed pronounced diet- and strain-dependent effects on weight, and triglyceride and insulin levels. Differences in fat mass, adipose tissue, and skeletal muscle glucose uptake, and gene expression changes in most tissues were strain-dependent. In visceral adipose tissue, ∼400 genes responded to diet in a strain-dependent manner, many of them in metabolite transport and lipid metabolism pathways and several previously identified to modify diet effects in humans. Thus, genetic background profoundly impacts metabolism, though chosen dietary patterns modify the strong genetic effects. This study paves the way for future mechanistic investigations into strain-diet interactions in mice and translation to precision nutrition in humans.

Published
2024
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26. Understanding corporate concerns. Barriers and challenges in corporate–start-up collaboration

Author

Michal Banka, Norbert Chmiel, Mariusz Kostrzewski, Magdalena Marczewska, Arkadiusz Michal Kowalski, Katarzyna Sedkiewicz, and Mariusz Salwin

Subjects
Start-ups, Corporates, Collaboration, Accelerator programme, Management. Industrial management, HD28-70, Business, HF5001-6182
Abstract

Despite increasing awareness of the benefits of partnerships with start-ups, corporates are often hesitant to collaborate due to perceived barriers, resulting in failed or suboptimal collaborations. This paper explores and assesses the key barriers that hinder corporates from successfully collaborating with startups. Based on a CAWI interviews with corporations, it evaluates both the significance and the severity of these obstacles, as well as the challenges involved in establishing effective partnerships. Additionally, the study examines how various corporate characteristics—such as company size, experience with startups, strategic approaches, and methods of engagement—impact the success of these collaborations. The findings reveal that corporates face significant challenges in partnering with startups. Major barriers include difficulties in identifying suitable startups, a lack of understanding of startup innovations, and concerns over financial risks associated with startup projects. Other obstacles, though less prominent, include fears of reputational damage if collaborations fail and limited support from corporate leadership for engaging with startups. This research highlights the need for enhanced strategies and knowledge-sharing to overcome these barriers, ultimately leading to more effective corporate-startup collaborations. This paper makes a key contribution by filling a significant research gap in the evaluation of barriers to corporate-startup collaborations, particularly by identifying new and unexplored obstacles that have not been previously documented in the literature. By expanding the catalogue of known barriers and analyzing corporate characteristics that affect collaboration outcomes, the study offers valuable insights for improving strategies and fostering more successful partnerships between corporates and startups.

Published
2024
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27. Identifying gamification factors for digital banking service users in Vietnam: Extending TAM model with gamification and perceived value

Author

Tran Viet Tam, Nguyen Hoang Tien, and Michal Banka

Subjects
Digital banking, perceived value, gamification, TAM, PLS-SEM, Vietnam, Business, HF5001-6182, Management. Industrial management, HD28-70
Abstract

This study explores the influence of gamification on level of acceptance of digital banking by users in Vietnam. Thence, the level of impact, the theoretical contributions and practical values for policy makers are determined. Research hypotheses are developed base on the original TAM model combined with gamification and perceived value factors. PLS-SEM method is used to carry out the research process of finding relationships between factors affecting users’ acceptance of digital banking in Vietnam with 262 complete survey results. The main results of this study have shown that gamification has positive affection on perceived value, attitude and behavioral intention of digital banking users. Additionally, the study suggests potential areas for future research to enhance the understanding and the application of gamification in digital banking.

Published
2024
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28. Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition.

Author

Palmer, Elizabeth, Pusch, Michael, Picollo, Alessandra, Forwood, Caitlin, Nguyen, Matthew, Suckow, Vanessa, Gibbons, Jessica, Hoff, Alva, Sigfrid, Lisa, Megarbane, Andre, Nizon, Mathilde, Cogné, Benjamin, Beneteau, Claire, Alkuraya, Fowzan, Chedrawi, Aziza, Hashem, Mais, Stamberger, Hannah, Weckhuysen, Sarah, Vanlander, Arnaud, Ceulemans, Berten, Rajagopalan, Sulekha, Nunn, Kenneth, Arpin, Stéphanie, Raynaud, Martine, Motter, Constance, Ward-Melver, Catherine, Janssens, Katrien, Meuwissen, Marije, Beysen, Diane, Dikow, Nicola, Grimmel, Mona, Haack, Tobias, Clement, Emma, McTague, Amy, Hunt, David, Townshend, Sharron, Ward, Michelle, Richards, Linda, Simons, Cas, Costain, Gregory, Dupuis, Lucie, Mendoza-Londono, Roberto, Dudding-Byth, Tracy, Boyle, Jackie, Saunders, Carol, Fleming, Emily, El Chehadeh, Salima, Spitz, Marie-Aude, Piton, Amelie, Gerard, Bénédicte, Abi Warde, Marie-Thérèse, Rea, Gillian, McKenna, Caoimhe, Douzgou, Sofia, Banka, Siddharth, Akman, Cigdem, Bain, Jennifer, Sands, Tristan, Wilson, Golder, Silvertooth, Erin, Miller, Lauren, Lederer, Damien, Sachdev, Rani, Macintosh, Rebecca, Monestier, Olivier, Karadurmus, Deniz, Collins, Felicity, Carter, Melissa, Rohena, Luis, Willemsen, Marjolein, Ockeloen, Charlotte, Pfundt, Rolph, Kroft, Sanne, Field, Michael, Laranjeira, Francisco, Fortuna, Ana, Soares, Ana, Michaud, Vincent, Naudion, Sophie, Golla, Sailaja, Weaver, David, Bird, Lynne, Friedman, Jennifer, Clowes, Virginia, Joss, Shelagh, Pölsler, Laura, Campeau, Philippe, Blazo, Maria, Bijlsma, Emilia, Rosenfeld, Jill, Beetz, Christian, Powis, Zöe, McWalter, Kirsty, Brandt, Tracy, Torti, Erin, Mathot, Mikaël, Mohammad, Shekeeb, Armstrong, Ruth, and Kalscheuer, Vera

Subjects
Male, Female, Humans, Neurodevelopmental Disorders, Mutation, Missense, Genes, X-Linked, Phenotype, Chloride Channels
Abstract

Missense and truncating variants in the X-chromosome-linked CLCN4 gene, resulting in reduced or complete loss-of-function (LOF) of the encoded chloride/proton exchanger ClC-4, were recently demonstrated to cause a neurocognitive phenotype in both males and females. Through international clinical matchmaking and interrogation of public variant databases we assembled a database of 90 rare CLCN4 missense variants in 90 families: 41 unique and 18 recurrent variants in 49 families. For 43 families, including 22 males and 33 females, we collated detailed clinical and segregation data. To confirm causality of variants and to obtain insight into disease mechanisms, we investigated the effect on electrophysiological properties of 59 of the variants in Xenopus oocytes using extended voltage and pH ranges. Detailed analyses revealed new pathophysiological mechanisms: 25% (15/59) of variants demonstrated LOF, characterized by a shift of the voltage-dependent activation to more positive voltages, and nine variants resulted in a toxic gain-of-function, associated with a disrupted gate allowing inward transport at negative voltages. Functional results were not always in line with in silico pathogenicity scores, highlighting the complexity of pathogenicity assessment for accurate genetic counselling. The complex neurocognitive and psychiatric manifestations of this condition, and hitherto under-recognized impacts on growth, gastrointestinal function, and motor control are discussed. Including published cases, we summarize features in 122 individuals from 67 families with CLCN4-related neurodevelopmental condition and suggest future research directions with the aim of improving the integrated care for individuals with this diagnosis.

Published
2023

29. Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues

Author

Spang, Martin T, Middleton, Ryan, Diaz, Miranda, Hunter, Jervaughn, Mesfin, Joshua, Banka, Alison, Sullivan, Holly, Wang, Raymond, Lazerson, Tori S, Bhatia, Saumya, Corbitt, James, D’Elia, Gavin, Sandoval-Gomez, Gerardo, Kandell, Rebecca, Vratsanos, Maria A, Gnanasekaran, Karthikeyan, Kato, Takayuki, Igata, Sachiyo, Luo, Colin, Osborn, Kent G, Gianneschi, Nathan C, Eniola-Adefeso, Omolola, Cabrales, Pedro, Kwon, Ester J, Contijoch, Francisco, Reeves, Ryan R, DeMaria, Anthony N, and Christman, Karen L

Subjects
Engineering, Biomedical Engineering, Biotechnology, Bioengineering, Cardiovascular, Neurosciences, Regenerative Medicine, Traumatic Head and Spine Injury, Heart Disease - Coronary Heart Disease, Heart Disease, Physical Injury - Accidents and Adverse Effects, Rats, Swine, Animals, Biocompatible Materials, Myocardium, Myocardial Infarction, Hydrogels, Extracellular Matrix, Biomedical engineering
Abstract

Decellularized extracellular matrix in the form of patches and locally injected hydrogels has long been used as therapies in animal models of disease. Here we report the safety and feasibility of an intravascularly infused extracellular matrix as a biomaterial for the repair of tissue in animal models of acute myocardial infarction, traumatic brain injury and pulmonary arterial hypertension. The biomaterial consists of decellularized, enzymatically digested and fractionated ventricular myocardium, localizes to injured tissues by binding to leaky microvasculature, and is largely degraded in about 3 d. In rats and pigs with induced acute myocardial infarction followed by intracoronary infusion of the biomaterial, we observed substantially reduced left ventricular volumes and improved wall-motion scores, as well as differential expression of genes associated with tissue repair and inflammation. Delivering pro-healing extracellular matrix by intravascular infusion post injury may provide translational advantages for the healing of inflamed tissues 'from the inside out'.

Published
2023

30. Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation

Author

Banka, Alison L, Guevara, M Valentina, Brannon, Emma R, Nguyen, Nhien Q, Song, Shuang, Cady, Gillian, Pinsky, David J, Uhrich, Kathryn E, Adili, Reheman, Holinstat, Michael, and Eniola-Adefeso, Omolola

Subjects
Biomedical and Clinical Sciences, Engineering, Biomedical Engineering, Hematology, Clinical Research, Cardiovascular, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Humans, Animals, Mice, Neutrophils, Inflammation, Thromboinflammation, Thrombosis, Blood Platelets, Leukocytes, P-Selectin
Abstract

The combination of inflammation and thrombosis is a hallmark of many cardiovascular diseases. Under such conditions, platelets are recruited to an area of inflammation by forming platelet-leukocyte aggregates via interaction of PSGL-1 on leukocytes and P-selectin on activated platelets, which can bind to the endothelium. While particulate drug carriers have been utilized to passively redirect leukocytes from areas of inflammation, the downstream impact of these carriers on platelet accumulation in thromboinflammatory conditions has yet to be studied. Here, we explore the ability of polymeric particles to divert platelets away from inflamed blood vessels both in vitro and in vivo. We find that untargeted and targeted micron-sized polymeric particles can successfully reduce platelet adhesion to an inflamed endothelial monolayer in vitro in blood flow systems and in vivo in a lipopolysaccharide-induced, systemic inflammation murine model. Our data represent initial work in developing cargo-free, anti-platelet therapeutics specifically for conditions of thromboinflammation.

Published
2023

33. Microbiology testing capacity and antimicrobial drug resistance in surgical-site infections: a post-hoc, prospective, secondary analysis of the FALCON randomised trial in seven low-income and middle-income countries

Author

Aboderin, Aaron Oladipo, Amfoabegyi, Solomon, Awopeju, Abimbola Temitayo, Bahrami-Hessari, Michael, Garchie, Emmanuel Isaac Acquah, Gill, Martin, Karikari, Akosua, Kirby, Andrew, Makanjuola, Olufunmilola, Mutiu, Bamidele, Offiong, Anthony Bassey, Oshun, Philip Olayiwola, Osumanu, Hisham Alhassan, Owusu-Ofori, Alex, Varghese, Shereen Rachel, Adam-Zakariah, Leslie Issa, Adebanjo, Ademola Tolulope, Aguirre, Celina Cuellar, Akoto, Erica, Aminu, Aliyu, Armah, Ralph, Aruldas, Neerav David, Choudhrie, Ashish V, Coompson, Christian Larbi, Ekwunife, Okechukwu Hyginus, Fourtounas, Maria, Lawani, Souliath, Mathew, Arpit Jacob, Patel, Akhil, Ademuyiwa, Adesoji O, Hardy, Pollyanna, Runigamugabo, Emmy, Sodonougbo, Pierre, Behanzin, Hulrich, Kangni, Sosthène, Agboton, Gérard, Adagrah, Luke Aniakwo, Adjei-Acquah, Esther, Acquah, Ato Oppong, Ankomah, James, Acquah, Regina, Addo, Kwame Gyambibi, Acheampong, Dorcas Otuo, Adu-Aryee, Nii Armah, Abubakari, Fatao, Titigah, Abraham, Owusu, Frank, Adu-Brobbey, Raphael, Adobea, Vivian, Abantanga, Francis Atindaana, Gautham, Arun, Bhatti, Dimple, Jesudason, Esther Daniel Mark, Aggarwal, Manisha, Alexander, Philip, Dasari, Amos, Alpheus, Rahul, Kumar, Hemanth, Raul, Subrat, Bueno, Wenceslao Ángeles, Ortiz, Reyes Cervantes, Gomez, Isaac Baltazar, Cerdan, Claudia Caballero, Gallo, Mariana Barreto, Gamez, Rozana Reyes, Sánchez, Irani Durán, Abdullahi, Lawal, Adesanya, Opeoluwa, Abdulsalam, Moruf, Adeleye, Victoria, Egwuonwu, Ochomma, Adeleke, Akeem, Adebayo, Francis, Chiejina, Godwin, Abayomi, Olukayode, Abdur-Rahman, Lukman, Ede, Jude, Ezinne, Uba, Kanyarukiko, Salathiel, Dusabe, Moses, Hirwa, Aime Dieudonne, Bucyibaruta, Georges, Adams, Mary Augusta, Birtles, Cheryl, Ally, Zain, Adewunmi, Abdus-sami, Cook, Jonathan, Brown, Julia, Adisa, Adewale O, Ismail, Lawani, Bhangu, Aneel, Omar, Omar, Simoes, Joana FF, Li, Elizabeth, Chaudhry, Daoud, Saeed, Samerah, Spurring, Eleanor Margaret, Verjee, Azmina, Assouto, Pamphile, Seto, Djifid Morel, Kpangon, Cyrile, Ahossi, Rene, Alhassan, Bin Baaba Alhaji, Agyekum, Vera, Assah-Adjei, Frank, Asare, Christopher, Amoako, James, Akosa, Enoch Appiah, Acquaye, Jane, Adjei, Faisal, Ballu, Cletus, Bennin, Amos, Abdulai, Darling Ramatu, Hepzibah, Alice, Bhatti, William, Paul, Priyadarshini K, Dhamija, Parth, Thomas, Josy, Jacob, Priya, Choudhrie, Ashish, Peters, Nitin, Sharma, Rajeev, Camacho, Francisco Barbosa, Gonzalez, Gonzalo Hernandez, Solano, David Dominguez, Flores, Ana Cortes, Menindez, Roque Lincona, Vazquez, Diana Gonzalez, Ado, Khadija, Awonuga, David, Adeniran, Abimbola, Ademuyiwa, Adesoji, Ekwunife, Okechukwu, Adenikinju, Wilson, Aisuodionoe-Shadrach, Oseremen, Edet, Ekpo, Abdus-Salam, Rukiyat, Adeleke, Nurudeen, Ekenze, Sebastian, Francis, Matthew, Mukaneza, Francine, Izabiriza, Emelyne, Kabanda, Elysee, Bunogerane, Gisele Juru, Crawford, Richard, Ivy, Mathete, Jayne, David, Cousens, Simon, Chakrabortee, Sohini, Ghosh, Dhruva, Gyamfi, Frank Enoch, Brant, Felicity, Fiogbe, Michel, Tandje, Yannick, Akpla, Marcelin, Ngabo, Raoul Baderha, Amoako-Boateng, Mabel Pokuah, Agyemang, Eric, Asabre, Esther, Boakye, Anthony Appiah, Gakpetor, Delali Akosua, Appiah, Akosua Dwamena, Boakye, Percy, Adinku, Michael, Barimah, Charles Gyamfi, Labaran, Abdul-Hamid, Dankwah, Fred, Acquah, Daniel Kwesi, Mary, Grace, Bir, Karan, Madankumar, Latha, Gupta, Himani, Zechariah, Pradeep, Kurien, Elizabeth, Vakil, Rakesh, Hernández, Aldo Bernal, Krauss, Rosa Hernandez, Avendaño, Alejandro Cuevas, Garcia, Rafael Toriz, Ojeda, Alejandro Gonzalez, Peón, Alberto Navarrete, Lara, Maria Martínez, Aliyu, Mohammed, Fasiku, Olushola, Ajai, Olalekan, Adeniyi, Oluwafunmilayo, Modekwe, Victor, Adeniyi, Olumide, Akaba, Godwin, Inyang, Akan, Adebayo, Sikiru, Adesola, Muideen, Enemuo, Vincent, Ikechukwu, Iweha, Mukantibaziyaremye, Deborah, Maniraguha, Hope Lydia, Mbonimpaye, Salomee, Habumuremyi, Sosthene, Ede, Chikwendu Jeffrey, Mbavhalelo, Cynthia, Laurberg, Soren, Smart, Neil, de la Medina, Antonio Ramos, Brocklehurst, Peter, Koco, Houenoukpo, Chobli, Hugues Herve, Bisimwa, Nathan, Appiah, Anthony Baffour, Akesseh, Rebecca Adjeibah, Boateng, Ruby Acheampong, Fosu, Godfred, Gawu, Victoria Sena, Aseti, Mark, Agbedinu, Kwabena, Ametefe, Elikem, Boateng, Guy Casskey, Owusu, Junior Atta, Doe, Stanley, Ayingayure, Emmanuel, Singh, Deepak, Daniel, Swati, Mittal, Rohin, Kanna, Vinoth, Mathew, Arpit, Arellano, Ana Bogurin, Miguelena, Luis Hernández, Sansores, Luis Dominguez, Velasco, Monica Jimenez, Muñoz, Maria Paz, Perez-Maldonado, Laura Martinez, Anyanwu, Lofty-John, Ogo, Chidiebere, Akande, Olukemi, Akinajo, Opeyemi, Okoro, Chukwuemeka, Adepiti, Akinfolarin, Ameh, Lazarus, Isa, Mary, Ajao, Akinlabi, Afolabi, Rafiat, Eze, Matthew, Nnyonno, Okoi, Munyaneza, Aphrodis, Mpirimbanyi, Christophe, Mukakomite, Christine, Haragirimana, Jean de Dieu, Moore, Rachel, Metchinhoungbe, Serge, Kovohouande, Blaise, Kandokponou, Covalic Melic Bokossa, Asante-Asamani, Alvin, Amponsah-Manu, Forster, Koomson, Barbara, Serbeh, Godwin, Obbeng, Ambe, Banka, Charles, Gyamfi, Brian, Agbeko, Anita Eseenam, Amoako, Joachim Kwaku, Luri, Prosper Tonwisi, Kantanka, Ruth Sarfo, Osman, Imoro, Dhar, Tapasya, Nagomy, Ida, Kumar, Ashwani, Prakash, Danita, Torres, Edgar Cortes, Romero, Marco Hurtado, Mejia, Hector Ortiz, de la Fuente, Alejandra Nayen Sainz, Magashi, Mahmoud, Atobatele, Kazeem, Akinboyewa, David, Uche, Chisom, Aderounmu, Adewale, Mbajiekwe, Ndubuisi, Iseh, Faith, Amusat, Olanrewaju, Agodirin, Sulaiman, Ezomike, Uchechukwu, Okoro, Philemon, Ndegamiye, Gibert, Mutuyimana, Josiane, Muroruhirwe, Piolette, Imanishimwe, Alphonsine, Hyman, Gabriella, Ntirenganya, Faustin, Sogbo, Hodonou, Dokponou, Mireille, Boakye, Benedict, Ofosu-Akromah, Richard, Kusiwaa, Ataa, Gyan, Kofi Yeboah, Ofosuhene, Doris, Dadzie, Samuel, Kontor, Bismark Effah, Amankwa, Emmanuel Gyimah, Attepor, Godsway Solomon, Kobby, Ephraim, Kunfah, Sheba, Dhiman, Jyoti, Selvakumar, Rajesh, Singh, Gurtaj, Susan, Anju, Orozco, Clotilde Fuentes, del Campo, Laura Urdapilleta Gomez, de la Medina, Antonio Ramos De, Muhammad, Abubakar, Eke, Grace, Alasi, Iyabo, Ugwuanyi, Kenneth, Adesunkanmi, Abdulhafiz, Ogbo, Felix, Marwa, Adams, Ayandipo, Omobolaji, Aremu, Isiaka, Izuka, Emmanuel, Patrick, Igwe, Tubasiime, Ronald, Mwenedata, Olivier, Ingabire, JC Allen, Khan, Zafar, Harrison, Ewen, Tabiri, Stephen, Glasbey, James, Dossou, Francis Moïse, Debrah, Samuel A, Enti, Donald, Twerefour, Emmanuel Yaw, Nyarko, Isaac Omane, Osei-Poku, Dorcas, Essien, Derick, Kyeremeh, Christian, Amoah, Michael, Brown, George Darko, Larnyor, Kennedy Kofi Korankye-Hanson, Limann, Gbana, Shankar, Bharat, Varghese, Rose, de Rojas, Erick González García, Muhammad, Saminu, Faboya, Omolara, Alakaloko, Felix, Ugwunne, Chuka, Adisa, Adewale, Olori, Samson, Ogbeche, Sunday, Egbuchulem, Kelvin, Bello, Jibril, Mbadiwe, Okezie, Raphael, John, Rwagahirima, Elisee, Mukanyange, Violette, Kwati, Morapedi, Dzemta, Corinne, Ganiyu, Rahman Adebisi, Robertson, Zelda, Puozaa, Diana, Manu, Ruth, Amoah, George, Fenu, Benjamin, Osei, Edwin, Mohammed, Shamudeen Alhassan, Goyal, Sunita, Sivakumar, Moonish, Muideen, Bello, Imam, Zainab, Atoyebi, Oluwole, Ajekwu, Samuel, Osagie, Olabisi, Olory, Edima, Ekwuazi, Hyginus, Lawal, Saheed, Mbah, Ngozi, Vaduneme, Oriji, Uwizeyimana, Francine, Munyaneza, Emmanuel, Mathe, Mpho Nosipho, Haque, Parvez D, Gaou, Antoine, Koggoh, Patience, Tackie, Enoch, Hussey, Romeo, Mensah, Elijah, Appiah, Juliana, Kumassah, Philemon Kwame, Owusu, Prince Yeboah, Mohammed, Sheriff, Goyal, Ankush, Sridhar, Rajeevan, Ramírez, Bertha Guzmán, Takai, Idris, Momson, Esther, Balogun, Olanrewaju, Ajenjfuja, Olusegun, Sadiq, Abu, Udie, Gabriel, Elemile, Peter, Lawal, Abdulwahab, Victor, Abhulimen, Zirikana, Job, Mutabazi, Emmanuel, Heritage, Emily, Goudou, Roland, Kpankpari, Richard, Temitope, Arkorful Ebenezer, Kwarteng, Jemima, Solae, Friko Ibrahim, Arthur, Joshua, Olayiwola, David Olatayo, Sie-Broni, Clement Ayum, Musah, Yakubu, Thomas, Cecil, Valadez, Michel Hernández Valadez, Ukata, Onyekachi, Nwaenyi, Francisca, Belie, Orimisan, Akindojutimi, Jerrie, Sani, Samuel, Udosen, Joseph, Lawal, Taiwo, Raji, Hadijat, Ncogoza, Isaie, Nhlabathi, Ncamsile Anthea, Hedefoun, Emmanuel, Opandoh, Isabella Naa M., Sowah, Naa Anyekaa, Toffah, Gideon Kwasi, Ayim, Alex, Wordui, Theodore, Zume, Marshall, Ofori, Bernard, Hans, Monika, Titus, Devabalan, Acevedo, Diego Luna, Ogunyemi, Ayokunle, Bode, Christopher, Akinkuolie, Akinbolaji, Tabuanu, Nancy, Usang, Usang, Lawal, Olatunji, Sayomi, Olayinka, Nxumalo, Hlengiwe Samkelisiwe, Kroese, Karolin, Houtoukpe, Sunday, Manu, Meshach Agyemang, Yeboah, Grace, Ayodeji, Emmanuel Kafui, Agboadoh, Nelson, Owusu, Emmanuel Abem, Haque, Parvez, Galaviz, Rubén Morán, Oludara, Mobolaji, Ekwesianya, Andrew, Alatise, Olusegun, Uanikhoba, Martins, Olagunju, Solomon, Shittu, Asimiyu, Nyirahabimana, Jeannette, Pattinson, Paddy, Lillywhite, Rachel, Lapitan, Carmela, Kamga, Felix, Manu, Maison Patrick Opoku, Yeboah, Cynthia, Boakye-Yiadom, Jonathan, Saba, Abdul-Hafiz, Konda, Samuel, Flores, Oscar Olvera, Omisanjo, Olufunmilade, Elebute, Olumide, Allen, Olubukola, Osuala, Peter, Urimubabo, Christian, Sentholang, Nnosa, Kiki-Migan, Eric, Mensah, Samuel, Boateng, Edward Amoah, Seidu, Anwar Sadat, Luther, Anil, Navarro, José Pérez, Oshodi, Olabode, Ezenwankwo, Francis, Amosu, Lukmon, Suleman, Bamidele, Sethoana, Mmule Evelyn, Lissauer, David, Morna, Martin Tangnaa, Dally, Charles, Mahajan, Amit, Belmontes, Kevin Pintor, Oshodi, Yusuf, Fatuga, Adedeji, Archibong, Micheal, Takure, Augustine, Stassen, Maria Elizabeth, Magill, Laura, Lawani, Ismaïl, Nkrumah, John, Davor, Anthony, Yakubu, Mustapha, Makkar, Shalini, Marbello, Fernando Ramirez, Oyewole, Yemisi, Ihediwa, George, Arowolo, Olukayode, Thornley, Laura, Morton, Dion, Loko, René, Nortey, Michael, Gyasi-Sarpong, Christian Kofi, Yenli, Edwin Mwintiereh Ta-ang, Mandrelle, Kavita, Ramírez-González, Luis, Salami, Omotade, Jimoh, Adesola, Ayantona, Deborah, Wondoh, Paul, Nepogodiev, Dmitri, Mistry, Punam, Moutaïrou, Afissatou, Ofori, Emmanuel Owusu, Hamidu, Naabo Nuhu Noel, Michael, Vishal, Aguirre, Laura Reyes, Williams, Omolara, Kuku, Jubril, Ayinde, Ademola, Monahan, Mark, Ogouyemi, Pencome, Quartson, Elizaberth Mercy Quartson, Haruna, Iddrisu, Mukherjee, Partho, García, Ramona Rojas, Ladipo-Ajayi, Oluwaseun, Badejoko, Olusegun, Soumanou, Fouad, Kwarley, Naa, Rajappa, Reuben, Robles, Eduardo Valtierra, Makanjuola, Ayomide, Badmus, Tajudeen, Smith, Donna, Tamadaho, Pia, Lovi, Agbenya Kobla, Singh, Prashant, Mokwenyei, Olayanju, Etonyeaku, Amarachukwu, Zounon, Mack-Arthur, Nimako, Boateng, Suroy, Atul, Nwokocha, Samuel, Igbodike, Emeka, Nyadu, Bertina Beauty, Thind, Ravinder, Ogein, Olubunmi, Ijarotimi, Omotade, Opoku, Dominic, Thomas, Alen, Ojewola, Rufus, Lawal, Adedayo, Pinkney, Thomas, Osabutey, Anita, Tuli, Arti, Oladimeji, Abraham, Nana, Fayowole, Roberts, Tracy, Sagoe, Robert, Veetil, Sreejith, Olajide, Thomas, Oduanafolabi, Tunde, Tuffour, Samuel, Oluseye, Oluwaseun, Olasehinde, Olalekan, Tufour, Yaa, Seyi-Olajide, Justina, Olayemi, Olaniyi, Winkles, Neil, Yamoah, Francis Akwaw, Soibi-Harry, Adaiah, Omitinde, Stephen, Yefieye, Abiboye Cheduko, Ugwu, Aloy, Oni, Owolabi, Yorke, Joseph, Williams, Emmanuel, Onyeze, Chigozie, Orji, Ernest, Rotimi, Adewale, Salako, Abdulkadir, Solaja, Olufemi, Sowemimo, Oluwaseun, Talabi, Ademola, Tajudeen, Mohammed, and Wuraola, Funmilola

Published
2024
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34. Discovery of DNA methylation signature in the peripheral blood of individuals with history of antenatal exposure to valproic acid

Author

Haghshenas, Sadegheh, Putoux, Audrey, Reilly, Jack, Levy, Michael A., Relator, Raissa, Ghosh, Sourav, Kerkhof, Jennifer, McConkey, Haley, Edery, Patrick, Lesca, Gaetan, Besson, Alicia, Coubes, Christine, Willems, Marjolaine, Ruiz-Pallares, Nathalie, Barat-Houari, Mouna, Tizzano, Eduardo F., Valenzuela, Irene, Sabbagh, Quentin, Clayton-Smith, Jill, Jackson, Adam, O’Sullivan, James, Bromley, Rebecca, Banka, Siddharth, Genevieve, David, and Sadikovic, Bekim

Published
2024
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35. Fuzzy inference system using genetic algorithm and pattern search for predicting roof fall rate in underground coal mines

Author

Ayush Sahu, Satish Sinha, and Haider Banka

Subjects
Underground coal mining, Roof fall, Fuzzy logic, Genetic algorithm, Mining engineering. Metallurgy, TN1-997
Abstract

Abstract One of the most dangerous safety hazard in underground coal mines is roof falls during retreat mining. Roof falls may cause life-threatening and non-fatal injuries to miners and impede mining and transportation operations. As a result, a reliable roof fall prediction model is essential to tackle such challenges. Different parameters that substantially impact roof falls are ill-defined and intangible, making this an uncertain and challenging research issue. The National Institute for Occupational Safety and Health assembled a national database of roof performance from 37 coal mines to explore the factors contributing to roof falls. Data acquired for 37 mines is limited due to several restrictions, which increased the likelihood of incompleteness. Fuzzy logic is a technique for coping with ambiguity, incompleteness, and uncertainty. Therefore, In this paper, the fuzzy inference method is presented, which employs a genetic algorithm to create fuzzy rules based on 109 records of roof fall data and pattern search to refine the membership functions of parameters. The performance of the deployed model is evaluated using statistical measures such as the Root-Mean-Square Error , Mean-Absolute-Error, and coefficient of determination ( $$R_2$$ R 2 ). Based on these criteria, the suggested model outperforms the existing models to precisely predict roof fall rates using fewer fuzzy rules.

Published
2024
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39. Comprehensive EHMT1 variants analysis broadens genotype-phenotype associations and molecular mechanisms in Kleefstra syndrome

Author

Rots, Dmitrijs, Bouman, Arianne, Yamada, Ayumi, Levy, Michael, Dingemans, Alexander J.M., de Vries, Bert B.A., Ruiterkamp-Versteeg, Martina, de Leeuw, Nicole, Ockeloen, Charlotte W., Pfundt, Rolph, de Boer, Elke, Kummeling, Joost, van Bon, Bregje, van Bokhoven, Hans, Kasri, Nael Nadif, Venselaar, Hanka, Alders, Marielle, Kerkhof, Jennifer, McConkey, Haley, Kuechler, Alma, Elffers, Bart, van Beeck Calkoen, Rixje, Hofman, Susanna, Smith, Audrey, Valenzuela, Maria Irene, Srivastava, Siddharth, Frazier, Zoe, Maystadt, Isabelle, Piscopo, Carmelo, Merla, Giuseppe, Balasubramanian, Meena, Santen, Gijs W.E., Metcalfe, Kay, Park, Soo-Mi, Pasquier, Laurent, Banka, Siddharth, Donnai, Dian, Weisberg, Daniel, Strobl-Wildemann, Gertrud, Wagemans, Annemieke, Vreeburg, Maaike, Baralle, Diana, Foulds, Nicola, Scurr, Ingrid, Brunetti-Pierri, Nicola, van Hagen, Johanna M., Bijlsma, Emilia K., Hakonen, Anna H., Courage, Carolina, Genevieve, David, Pinson, Lucile, Forzano, Francesca, Deshpande, Charu, Kluskens, Maria L., Welling, Lindsey, Plomp, Astrid S., Vanhoutte, Els K., Kalsner, Louisa, Hol, Janna A., Putoux, Audrey, Lazier, Johanna, Vasudevan, Pradeep, Ames, Elizabeth, O'Shea, Jessica, Lederer, Damien, Fleischer, Julie, O'Connor, Mary, Pauly, Melissa, Vasileiou, Georgia, Reis, André, Kiraly-Borri, Catherine, Bouman, Arjan, Barnett, Chris, Nezarati, Marjan, Borch, Lauren, Beunders, Gea, Özcan, Kübra, Miot, Stéphanie, Volker-Touw, Catharina M.L., van Gassen, Koen L.I., Cappuccio, Gerarda, Janssens, Katrien, Mor, Nofar, Shomer, Inna, Dominissini, Dan, Tedder, Matthew L., Muir, Alison M., Sadikovic, Bekim, Brunner, Han G., Vissers, Lisenka E.L.M., Shinkai, Yoichi, and Kleefstra, Tjitske

Published
2024
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40. Pathogenic variants in KMT2C result in a neurodevelopmental disorder distinct from Kleefstra and Kabuki syndromes

Author

Rots, Dmitrijs, Choufani, Sanaa, Faundes, Victor, Dingemans, Alexander J.M., Joss, Shelagh, Foulds, Nicola, Jones, Elizabeth A., Stewart, Sarah, Vasudevan, Pradeep, Dabir, Tabib, Park, Soo-Mi, Jewell, Rosalyn, Brown, Natasha, Pais, Lynn, Jacquemont, Sébastien, Jizi, Khadijé, Ravenswaaij-Arts, Conny M.A. van, Kroes, Hester Y., Stumpel, Constance T.R. M., Ockeloen, Charlotte W., Diets, Illja J., Nizon, Mathilde, Vincent, Marie, Cogné, Benjamin, Besnard, Thomas, Kambouris, Marios, Anderson, Emily, Zackai, Elaine H., McDougall, Carey, Donoghue, Sarah, O'Donnell-Luria, Anne, Valivullah, Zaheer, O'Leary, Melanie, Srivastava, Siddharth, Byers, Heather, Leslie, Nancy, Mazzola, Sarah, Tiller, George E., Vera, Moin, Shen, Joseph J., Boles, Richard, Jain, Vani, Brischoux-Boucher, Elise, Kinning, Esther, Simpson, Brittany N., Giltay, Jacques C., Harris, Jacqueline, Keren, Boris, Guimier, Anne, Marijon, Pierre, Vries, Bert B.A. de, Motter, Constance S., Mendelsohn, Bryce A., Coffino, Samantha, Gerkes, Erica H., Afenjar, Alexandra, Visconti, Paola, Bacchelli, Elena, Maestrini, Elena, Delahaye-Duriez, Andree, Gooch, Catherine, Hendriks, Yvonne, Adams, Hieab, Thauvin-Robinet, Christel, Josephi-Taylor, Sarah, Bertoli, Marta, Parker, Michael J., Rutten, Julie W., Caluseriu, Oana, Vernon, Hilary J., Kaziyev, Jonah, Zhu, Jia, Kremen, Jessica, Frazier, Zoe, Osika, Hailey, Breault, David, Nair, Sreelata, Lewis, Suzanne M.E., Ceroni, Fabiola, Viggiano, Marta, Posar, Annio, Brittain, Helen, Giovanna, Traficante, Giulia, Gori, Quteineh, Lina, Ha-Vinh Leuchter, Russia, Zonneveld-Huijssoon, Evelien, Mellado, Cecilia, Marey, Isabelle, Coudert, Alicia, Aracena Alvarez, Mariana Inés, Kennis, Milou G.P., Bouman, Arianne, Roifman, Maian, Amorós Rodríguez, María Inmaculada, Ortigoza-Escobar, Juan Dario, Vernimmen, Vivian, Sinnema, Margje, Pfundt, Rolph, Brunner, Han G., Vissers, Lisenka E.L.M., Kleefstra, Tjitske, Weksberg, Rosanna, and Banka, Siddharth

Published
2024
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41. DNA methylation analysis in patients with neurodevelopmental disorders improves variant interpretation and reveals complexity

Author

Trajkova, Slavica, Kerkhof, Jennifer, Rossi Sebastiano, Matteo, Pavinato, Lisa, Ferrero, Enza, Giovenino, Chiara, Carli, Diana, Di Gregorio, Eleonora, Marinoni, Roberta, Mandrile, Giorgia, Palermo, Flavia, Carestiato, Silvia, Cardaropoli, Simona, Pullano, Verdiana, Rinninella, Antonina, Giorgio, Elisa, Pippucci, Tommaso, Dimartino, Paola, Rzasa, Jessica, Rooney, Kathleen, McConkey, Haley, Petlichkovski, Aleksandar, Pasini, Barbara, Sukarova-Angelovska, Elena, Campbell, Christopher M., Metcalfe, Kay, Jenkinson, Sarah, Banka, Siddharth, Mussa, Alessandro, Ferrero, Giovanni Battista, Sadikovic, Bekim, and Brusco, Alfredo

Published
2024
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42. Menke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles

Author

Angius, Andrea, Baker, Janice A., Bedoukian, Emma, Bhambhani, Vikas, Bodamer, Olaf, O’Brien, Alan, Clayton-Smith, Jill, Crisponi, Laura, Cueto González, Anna María, the DDD study, Devriendt, Koenraad, Garrido, Elena Dominguez, Ehmke, Nadja, van Eerde, Albertien, van den Elzen, Annette P.M., Faivre, Laurence, Fisher, Laura, Flores-Daboub, Josue A., Foster, Alison, Friedman, Jennifer, Gabau, Elisabeth, Galazzi, Elena, García-Miñaúr, Sixto, Garavelli, Livia, Gardeitchik, Thatjana, Gerkes, Erica H., van Gils, Julien, Giltay, Jacques C., Garcia, Aixa Gonzalez, Heimdal, Ketil Riddervold, Horn, Denise, Houge, Gunnar, Hufnagel, Sophia B., Ilencikova, Denisa, Julia, Sophie, Kant, Sarina G., Kinning, Esther, Klee, Eric W., Kois, Chelsea, Kovačević, Maja, Lachmeijer, A.M.A. (Guus), Lanpher, Brendan, Lebrun, Marine, Leon, Eyby, Lichty, Angie Ward, Lin, Ruth, Llano-Rivas, Isabel, Lynch, Sally Ann, Maas, Saskia M., Maitz, Silvia B., McKee, Shane, Melis, Daniela, Merati, Elisabetta, Merla, Giuseppe, Newbury-Ecob, Ruth, Nizon, Mathilde, Park, Soo-Mi, Patterson, Jennifer, Petit, Florence, Peeters, Hilde, Persani, Luca, Persico, Ivana, Pes, Valentina, Pollazzon, Marzia, Potjer, Thomas, Potocki, Lorraine, Pottinger, Carrie, Prasad, Chitra, Prijoles, Eloise J., Ragge, Nicola K., Rake, Jan Peter, van Ravenswaaij-Arts, Conny M.A., Rea, Gillian, Ruivenkamp, Claudia, Rutz, Audrey, Saitta, Sulagna C., Russo, Rossana Sanchez, Santen, Gijs W.E., Schaefer, Elise, Shashi, Vandana, Schultz-Rogers, Laura, Sluga, Andrea, Sotgiu, Stefano, Steichen-Gersdorf, Elisabeth, Sullivan, Jennifer A., Sun, Yu, Suri, Mohnish, Tartaglia, Marco, Tedder, Matt, Terhal, Paulien, Tully, Ian, Verbeek, Nienke, Wenzel, Maren, White, Susan M., Xiao, Bing, Haghshenas, Sadegheh, Bout, Hidde J., Schijns, Josephine M., Levy, Michael A., Kerkhof, Jennifer, Bhai, Pratibha, McConkey, Haley, Jenkins, Zandra A., Williams, Ella M., Halliday, Benjamin J., Huisman, Sylvia A., Lauffer, Peter, de Waard, Vivian, Witteveen, Laura, Banka, Siddharth, Brady, Angela F., Hurst, Anna C.E., Kaiser, Frank J., Lacombe, Didier, Martinez-Monseny, Antonio F., Fergelot, Patricia, Monteiro, Fabíola P., Parenti, Ilaria, Santos-Simarro, Fernando, Simpson, Brittany N., Alders, Mariëlle, Robertson, Stephen P., Sadikovic, Bekim, and Menke, Leonie A.

Published
2024
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43. Access to and quality of elective care: a prospective cohort study using hernia surgery as a tracer condition in 83 countries

Author

Dönmez, A Eylül, Goswami, Aakansha Giri, Raheja, Aashna, Bhadani, Aayush, El Kady, Abd Elrahman Safwat, Alniemi, Abdalaziz, Awad, Abdalkarim, Aladl, Abdalla, Younis, Abdalla, Alwali, Abdallah, Khalil, Abdallah, Mansour, Abdallah, Elkhouly, Abdallah Mohamed, Rashad Temerik, Abdallah, Hasan, Abdallatef, Chied, Abdelhafid, Abdraba, Abdelhamid, Hrora, Abdelmalek, Abdelshafi, Abdelrahman, Alwali, Abdelrahman, Maraqa, Abdelrahman, Ghaffar, Abdul, Chekfa, Abdul Jabar, Al Balushi, Abdul Majeed, Quddus, Abdul, Hammadieh, Abdul Rahman, Muntaka, Abdul-Jalilu Mohammed, Asekun, Abdulazeez, Alshahrani, Abdulaziz, Jowharji, Abdulaziz, Alshukre, Abdulbaset, Khair Etareig, Abdulhafid, Abubakar Abdulkarim, Abdulhafiz, Ashiru, Abdulhafiz, Alailesh, Abdulhamid, Al-Mallah, Abdullah, Baydoun, Abdullah, Chaudhry, Abdullah, Askin, Abdullah Emre, Almutairi, Abdulmjeed, Belkhair, Abdulmunem, Abdllah, Abdulrahman, Alhammali, Abdulrahman, Basalim, Abdulrahman, Abouelnagah, Abdulrahman Galal Mohamed Mostafa, Ghazal, Abdulrahman, Mohammed, Abdulrahman, Qasem, Abdulrahman, Anadani, Abdulrazak, Jimoh, Abdulrazaq, Lawal, Abdulrazzaq Oluwagbemiga, Khaity, Abdulrhman, Lawal, Abdulwahab, Elzoubi, Abdurrahim Esseid, Sheshe, Abdurrahman Abba, Cetişli, Abdurrahman Furkan, Oyedele, Abeeb, Aljahdali, Abeer, Aboelnasr, Abeer Gamal Elsyed, Demessie, Abel, Bhargava, Abhilasha, Sonkar, Abhinav Arun, Bavaharan, Abhirame, Khan, Abid, Campbell, Abigail, Oyelekan, Abimbola Adeola Akintunde, Okunlola, Abiodun Idowu, Ojewuyi, Abiodun, Ekerin, Abiola, Saleh, Abobakr, Khairy, Abouelatta, Muthunayagam, Abraham Benjamin, Botha, Abraham, Teshome Sahilemariam, Abraham, Nawawi, Abrar, Muhammad, Abubakar Bala, Dahiru, Abubakar, Yahaya, Abubakar, Abdelmalik, Abubaker, Anuar, Abul Akmal Arif, Ousseini, Adakal, Leon -Del- Angel, Adalberto, Frankel, Adam, Gyedu, Adam, Lim, Adam, Lukáč, Adam, Peckham-Cooper, Adam, Sabbah, Adam, Varga, Adam, Sanou, Adama, Issaka, Adamu, Ningi, Adamu, Yeshitila, Addis, Yingess, Addisu, Olugbami, Adebayo, Moses, Damola-Okesiji, Adebola, Lawal, Adedayo, Ojo, Adedoyin, Hashmi, Adeel, Fakoya, Adegbolahan, Ishola, Adegoke, Abiodun, Adekunle, Ajayi, Adekunle, Mouffokes, Adel, Bonelli, Adele, Adekoya, Adeleke, Akeem Aderogba, Adeleke, Özcan, Adem, Ayoade, Ademidun, Adeyeye, Ademola, Agbaje, Ademola, Talabi, Ademola, Ademuyiwa, Adesoji, Adewumiya, Adesoji, Ademuyiwa, Adesoji O, Aderounmu, Adewale, Adisa, Adewale, Oke, Adewale, Ragab, Adham, Alzadjali, Adil, Baksi, Aditya, Jayapalan, Aditya, Md Yunos, Adnan, Pisanu, Adolfo, Salazar, Adolfo, Salinas Barragan, Adrian Alberto, Fox, Adrian, Stollberg, Adrian, Franco, Adriana, Neves, Adriana, Vricheva, Adriana, Hodonou, Adrien Montcho, Aghayeva, Afag, Liaquat, Affifa, Alsultan, Afnan, Morad, Afnan, Kalidis, Afroditi Angella, Gkouniaroudi, Agathi, Karakosta, Agathi, Lovi, Agbenya, Yevide, Agossou Barthélémy, Duro, Agustin, Rodriguez Gonzalez, Agustin, Tariq, Ahbala, Abaidalla, Ahmad, Abuhammad, Ahmad, Abuhantash, Ahmad, Mansour, Ahmad Adel, Ahmad Zaidi, Ahmad Al Hafeez, Alahmad Alismael, Ahmad, Alayed, Ahmad, Alfarwan, Ahmad, Alhaj, Ahmad, Ali, Ahmad, Alroobi, Ahmad, Alsheikh, Ahmad, Alusef, Ahmad, Alzu'Bi, Ahmad, Kayali, Ahmad Amir, Bouhuwaish, Ahmad, Doghaim, Ahmad, El-Sherbiney, Ahmad, Ghazal, Ahmad, Ramly, Ahmad Nasir, Raza, Ahmad, Qureshi, Ahmad Uzair, Arnaout, Ahmad Yamen, Abdelhamid, Ahmed, Abuthaher, Ahmed, Adel, Ahmed, Ahmayda, Ahmed, Al-Mouahhed, Ahmed, Alagha, Ahmed, Albalawi, Ahmed, Albhaisi, Ahmed, Alrifaee, Ahmed, Azam, Ahmed, Barakat, Ahmed, Al-Hajjaj, Ahmed Basim Abed, Dawoud, Ahmed, El Shamarka, Ahmed, El-Bastwesy, Ahmed, Elghrieb, Ahmed, Elkhalifa, Ahmed, Elmosalamy, Ahmed, Elshazli Mahmoud, Ahmed, Montaser, Ahmed G., Gbeadese, Ahmed, Haty, Ahmed, K. Ali, Ahmed, Awad, Ahmed K., Kedwany, Ahmed, Khalleefah, Ahmed, Abbas, Ahmed M., Allam, Ahmed M., Maher, Ahmed, Elsayed, Ahmed Mohamed, Mohamed Ibrahim Mohamed, Ahmed, Mostafa, Ahmed, Nabil, Ahmed, Nada, Ahmed, Ragheb, Ahmed, Abdelrahman, Ahmed Saber Mohamed, Sabry, Ahmed, Sakr, Ahmed, Elkhodary, Ahmed Salah, Shaheen, Ahmed, Ammar, Ahmed Siddique, Hameed, Ahmer, Akmercan, Ahmet, Aslan, Ahmet, Barcin, Ahmet, Ciftci, Ahmet Burak, Bozkurt, Ahmet Çağlar, Sarı, Ahmet Can, Yaşar, Ahmet Can, Develioğlu, Ahmet, Öztürk, Ahmet Mücteba, Sanli, Ahmet Necati, Rencuzogullari, Ahmet, Yildiz, Ahmet, Kaan, Ahmet Zahit, Toi, Ahouefa Chourika Sakinath, Aljamoudi, Aida, Cheung, Aiden Chak Kei, Gkoutoula, Aikaterini, Kalogeropoulou, Aikaterini, Sarafi, Aikaterini, Abo Al Shamat, Aiman, Sanon, Aimé Serge Titianma, Sanon, Aimée Florence, Hiller, Aimée, Costas-Chavarri, Ainhoa, Lombardero, Ainhoa, Fraile, Ainoa, Bojazyah, Aisha, Kamal, Aisha, Gill, Aisling, Hada, Aïssatou, Gulla, Aiste, Mačiulaitytė, Aistė, 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Daniel, Montwedi, Daniel, Muñoz, Daniel, Patterson, Daniel, Reim, Daniel, Agbley, Daniel Yao Dodzie, Patiño García, Daniela Cristina, Di Pietrantonio, Daniela, Pais, Daniela, Rosado, Daniela, Tavares, Daniela, Alberti, Daniele, Fusario, Daniele, Massaro, Daniele, Paglione, Daniele, Pironi, Daniele, Kurochka, Daniil, Centonze, Danilo Corrado, Hackner, Danilo, Herrera, Danilo, Amangaliyev, Daniyar, Silva-Cano, Danny Wladimir, Chaudhry, Daoud, Palmisano, Dario, Ribero, Dario, Vukosav, Dario, Misca, Darius, Lowen, Darren, Rattray, Darren, Walia, Darshanjit Singh, Maan, Darvesh, Muyenzi, Daryle, Verdi, Daunia, Bardsley, David, Reyes Rodríguez, David Estuardo, Fra Corral, David, Garcia López De Goicoechea, David, Gavit, David, Gómez, David, Idowu, David, Konkin, David, Labadah, David Kplorla Kekeli, Liu, David, Merlini, David, Mitchell, David, Moro-Valdezate, David, Osifo, David, Proud, David, Ridder, David, Gobatti, Davide, Muschitiello, Davide, Pertile, Davide, Zulian, Davide, Mengiste, Dawit, Mikami, Dean, Mohanty, Debajyoti, Chatterjee, Debarghya, Komolafe, Deborah Olaitan, Scotto Di Carlo, Deborah, Wright, Deborah, Rahme, Deema, Talreja, Deep Parkash, Jain, Deepak, Rajput, Deepak, Singh, Deepak, Anbu, Deepika, Ibrahim, Dena, Phom, Denchu, Hili, Denise, Osei, Dennis Broni, Daary, Dennis, Kyeremeh, Dennis, Shen, Dennis, Uymaz, Derya Salim, Cianflocca, Desiree, Ashitey, Desmond, Evripidou, Despo, Papageorgouli, Despoina, Kaushal, Devesh, Abeysirigunawardana, Dewmi, Dugar, Dharmendra, Mallik, Dhiraj, Ghosh, Dhruva, Houmran, Diaa, Abdulrahman, Diala, Pantoja Pachajoa, Diana Alejandra, Cardona Gomez, Diana Catalina, Fenner, Diana, Gonzalez, Diana Samantha, Siriwardena, Diana, Garcés Palacios, Diana Sofía, Stoian, Diana, Zuikyte, Diana, Sosa Méndez, Dianne Alitzá, Wickramarathna, Dickson, Mutter, Didier, Palma Portillo, Diego Andrés, Chavez Fernandez, Diego, Córdova García, Diego, Enjuto, Diego, Giulitti, Diego, Sasia, Diego, Visconti, Diego, Yiğit, Dilara, George, Dilip, Rabaia, Dima, Georgiev, Dimitar, Hadzhiev, Dimitar, Alexandrou, Dimitrios, Balalis, Dimitrios, Giakoustidis, Dimitrios, Manatakis, Dimitrios K., Korkolis, Dimitrios, Lytras, Dimitrios, Massaras, Dimitrios, Moris, Dimitrios, Politis, Dimitrios, Sampanis, Dimitrios, Schizas, Dimitrios, Tsiardas, Dimitrios, Vardakostas, Dimitrios, Kotsaris, Dimitris, Khattab, Dina Hesham, M. Awad, Dina, Alrokh, Dina Sami, Schippers, Dina, Waleed, Dina, Salinovic, Dinko, Gonçalves Múrias Gomes, Diogo Miguel, Silva, Diogo, Vaz Acosta, Diogo, Morton, Dion, Panagopoulos, Dionisios, Kelgiorgi, Dionysia, Dellaportas, Dionysios, Prevezanos, Dionysios, Joshi, Dipti, Ozal, Direm, Yigit, Direnc, Chimkaomasiri, Divine, Jabbar, Diya, Nepogodiev, Dmitri, Belekar, Dnyanesh, Abdalaziz, Doaa, Abunemer, Doaa, Attia, Doaa, Elkafrawy, Doaa, Dimitrov, Dobromir, Pignatelli, Domenica, Merlicco, Domenico, Soriero, Domenico, Zerbo, Domenico, Atouguia, Domingas, Fairbrass, Dominic, T. Enti, Donald, Venskutonis, Donatas, Rukavina, Dora, Caruso, Dorena, Herappe, Dorihela, Lee, Dorinda Norbetha, Ofosuhene, Doris, Hajela, Apoorva, Badwan, Basem, Kulkarni, Datta, Dhawan, Deep, Dhillon, Jeevanjit, Mehmood, Manzer, Mahmood, Namrah, Nikam, Narendra, Ramchandani, Radhakrishna, Thind, Ravinder Singh, Riazhussain, D Hafiz, Maqsood, Saliha, Alalawi, Yousef, Tyagi, Harshdeep, Kshirsagar, Shivani, Ahmed, Hisham, Juan Carlos, Luna Cydejko, Kone, Dramane, Omar, Duaa, Alves, Duarte Gil, Subasinghe, Duminda, Ommi, Durgesh, Joshiba, Durshney, Chakarov, Dzhevdet, Arkoh, Ebenezer Ameyaw, Frimpong-Manso, Ebenezer, Ada, Ece, Lincango, Eddy P., Lozada Hernandez, Edgard Efren, Hodžić, Edin, Di Marco, Edith, Baccalini, Edoardo Andrea, Baldini, Edoardo, González Marín, Eduardo, Gutierrez, Eduardo, Sepúlveda, Eduardo, Dainius, Edvinas, Zhang, Edward, Yenli, Edwin Mwintiereh Ta-Ang, Antoniou, Efstathios, Kapasakis, Efstathios, Baili, Efstratia, Poulios, Efthymios, Kubiliute, Egle, Osaze, Ehioghae, Afeikhena, Ehis, Elshennawy, Eiad, Athanasopoulou, Eirini, Synekidou, Eirini, Ekaladze, Eka, Tampaki, Ekaterini Christina, Adam, Elaf, Adel Hamdoun Aziz, Elaf, Yousuf, Elamin, Gialamas, Eleftherios, Spartalis, Eleftherios, Bedzhanyan, Elen, Toma, Elena Adelina, Daukšaitė, Elena, Desiato, Elena, Dvivedi, Elena, Hadzhieva, Elena, Martí Cuñat, Elena, Montalbán Martínez, Elena, Montanari, Elena, Signaroli, Elenasofia, Efremidou, Eleni, Gavriil, Eleni, Karakeke, Eleni, Mavrodimitraki, Eleni, Papamattheou, Eleni, Jose, Elenza, Cianci, Eleonora, Ciccioli, Eleonora, Daleva, Eleonora, Locci, Eleonora, Lori, Eleonora, Silanos, Eleonora, Ayala, Elí, Bankart, Eliana, Brolese, Eliane, Efstathiou, Elias, Salloum, Elias, Colak, Elif, Terzi, Elif Didem, Ametefe, Elikem, Cagigal Ortega, Elima Pilar, Donnarumma, Elio, Mina, Elisa, Reitano, Elisa, Wallner, Elisabeth, Moggia, Elisabetta, Betz, Elise, Kontis, Elissaios, Anestiadou, Elissavet, Gimson, Eliza, Lun, Elizabeth, Fraser, Elizabeth, Li, Elizabeth, Torres De Anda, Elizabeth Magaly, Murphy, Elizabeth Mary Ann, O'Connell, Elizabeth, Redondo, Elizabeth, Lun, Elizabeth Weng Yan, Francis, Ella, Haiden, Elmar, Hamed, Elmonzir, Alkhalifa, Elmustafa, Dexter, Eloise, Daketsey, Elorm, Setsoafia, Elorm, Mohamed, Elsagad, Mohammed, Elsamoual, Hegab, Elsayed, Ay, Elvin, Adinolfi, Elvira, Mbanzabugabo, Elvis, Chin, Elynn, Ahmed, Emad Ali, Younes, Eman, Basile, Emanuela, Gessa, Emanuela, Pontecorvi, Emanuele, Romairone, Emanuele, Hatangimana, Eméry, Ndizeye, Emile, Ciofic, Emilia, Dijan, Emilio, López-Negrete Cueto, Emilio, Baker, Emily, Reid, Emily, Schmidt, Emily, Alić, Emir, Bičakčić, Emir, Agbowada, Emma, Colton, Emma, Downing, Emma, Haege, Emma, O'Neill, Emma, Roussos, Emmanouel, Nachelleh, Emmanuel Aadereyir, Adebunmi, Emmanuel, Obiesie, Emmanuel Ahuizechukwu, Akakpo, Emmanuel Bismark, Konlan, Emmanuel Dammigu Francis, Nwangwu, Emmanuel Ifeanyi, Kafui Ayodeji, Emmanuel, Ofori, Emmanuel Owusu, Spanoudakis, Emmanuel, Abate, Emmanuele, Balik, Emre, Bozdağ, Emre, Bozkurt, Emre, Karabulut, Emre Cagri, Ozoran, Emre, Tunçcan, Emre, Tuzuner, Emre, Halilović, Emsad, Alabed, Enaam, Zidan, Enas, Hodžić, Enes, Aybar, Engin, Yildirim, Engin Okan, Wong, Enoch, Yhoshu, Enono, Bisogno, Enrica, Andolfi, Enrico, Ferri, Enrico, Potenza, Enrico, Spalice, Enrico, Volpin, Enrico, González, Enrique, Downes, Eoin, Gallo, Erdachew, Kamer, Erdinc, Naidoo, Eressa, Erginöz, Ergin, Bara, Eric, Irungu, Eric, García-Villegas, Eric Yusif, Mazzotta, Erica, Monati, Erica, Chan, Erick, Gómez Mejía, Erika, Dylja, Eris, Somuncu, Erkan, Yavuz, Erkan, Begunić, Ernes, Margelis, Ernest, Osei, Ernest Owusu, Saitoglou, Ertzan, Agastra, Ervis, Mazumdar, Eshan, Soyer Güldoğan, Esra, Abu Siam, Esra'A, Abdelbaset, Esraa, Abdu, Esraa, Adel Mahmod Sultan, Esraa, Nubi Mohamed, Esraa Gamal, Abuobaida Banaga Hag El Tayeb, Essam Eldien, Ali, Essraa, Page-Taylor, Estelle, Marra, Ester, Garcia Santos, Esther Pilar, Elsheikh, Ethar, Unal, Ethem, Tan, Eugene, De Leo, Eugenio, Borges, Eva, Gáspár, Éva, Ruiz-Daum, Eva, Apostolopoulos, Evaggelos, Samara, Evangelia, Barkolias, Evangelos, Fradelos, Evangelos, Hopping, Eve, Romo Ascencio, Evelia Veronica, Sosa Ferreira, Ever David, Shestakov, Evgenii, Tyurina, Evgenya, Hristova, Evguenia, Efthymiou, Evripidis, Tokidis, Evripidis, Harrison, Ewen, Dontoh, Ewurama Akroma, Mansour, Eyad, Yeshialem, Eyosiyas, Dabbagh, Ezeddin, Amer, Ezzeldin, Manasci, Fabiana, Gomes, Fabio, Medas, Fabio, d'Acapito, Fabrizio, Vassallo, Fabrizio, Haddad, Fadi, Elhabishi, Fadwa, Akhtar, Fahad, Tauheed, Fahad, Al Abbood, Fahd, Gareb, Fahed, Ghazali, Fairuz, Alnazawi, Faisal, Ondago, Faith, Rasoaherinomenjanahary, Fanjandrainy, Wiese, Fanny, González Ponce, Fanny Yesenia, Georgiades, Fanourios, Ali, Farah, Galley, Fareeda, Huda, Farhanul, Amir, Farhat Naaz, Ashraf, Fariha, Alfarsi, Faris, Ayasra, Faris, Ali, Farman, Mahmoud, Faten, Aliskander, Fater, Tahir Lwdie, Fathea, Buyuker, Fatih, Aguilar Del Castillo, Fátima, Mohammed Daoud, Fatima Ahmed, Alowjaly, Fatima, Oni, Fatima, Rauf, Fatima, Elkhafeefi, Fatimah, Hourri, Fatine, Monib, Fatma A., Alshreef, Fatma, Benghalbon, Fatma, Ntirenganya, Faustin, Ashraf, Fauziyah, Chahrour, Fayez, Ahmad, Fazal, Parray, Fazlul Qadir, Philips, Febi, Campus, Federica, Di Marco, Federica, Ferraina, Federica, Frongia, Federica, Maffeis, Federica, Natali, Federica, Pederiva, Federica, Scolari, Federica, Tofani, Federica, Marin, Federico Alberto Niccolò, Biolchini, Federico, Cappellacci, Federico, Corronca, Federico, Mazzola, Federico, Suldrup, Federico, Nyarko, Felicia, Casas J, Felipe, Zapata, Felipe, Aigner, Felix, Alakaloko, Felix, Amoako, Felix, Camacho, Felix, Hammett, Felix, Kuubetersob B. N, Felix, Alahmad, Feras, Alnimri, Feras, Haddad, Feras, Gool, Ferhana, Castro, Fernanda, Diaz, Fernanda, Lucero, Fernanda, Vovola, Fernanda, Mahnic, Fernando, Mercado Sanchez, Fernando, Prieto La Noire, Fernando, Soggiu, Fiammetta, Tsige, Fikreab, Brzeszczyński, Filip, Rudisch, Filip, Valente Costa Pinto, Filipa, Ramalho De Almeida, Filipe, Banchini, Filippo, Palomino Escalante, Fiorella, Fadzlullah, Fitri, Terefe, Fitsum, Sulo, Fjorenta, Ciccarone, Flavia, Tirelli, Flavio, Krämer, Florian, Grama, Florin, Spanos, Foivos, Solimene, Folco, Akinwande, Foluso, Osman, Forzia, Stefou, Foteini, Kyramargios, Fotios, Stavratis, Fotios, Alassani, Fousseni, Ascari, Francesca, Cammelli, Francesca, D'Agostino, Francesca, Tropeano, Francesca Paola, Peters, Francesca, Ré, Francesca, Brucchi, Francesco, Casti, Francesco, Coratti, Francesco, Ferrara, Francesco, Floris, Francesco, Izzo, Francesco, Maffei, Francesco, Palmieri, Francesco, Pata, Francesco, Porcelli, Francesco, Selvaggi, Francesco, Velluti, Francesco, Mulita, Francesk, Bello, Francis, Caiquo, Francis, Dossou, Francis, Eshun, Francis Junior, Opoku Twene, Francis, Tierenye, Francis, Quayson, Francis William, Romo Rosales, Francisco David, Ibañez Ortiz, Francisco, León Frutos, Francisco Javier, Redondo Calvo, Francisco Javier, Silva Rivera, Francisco Javier, Barbosa Camacho, Francisco José, Bujalance Cabrera, Francisco Manuel, Ruescas, Francisco, Irakiza, Franck Fanon, Corvatta, Franco, Pascual, Franco Raúl, Roviello, Franco, Roodt, Francois, Gyamfi, Frank Enoch, Olaniru, Frank, Owusu, Frank, Bader, Franz G., Anzinger, Franz-Xaver, Agbodo, Fred David Anku, Ris, Frederic, Agbemafoh, Frederick Mawuli, Afonso, Frederico, Nazareth, Frederico, Berrevoet, Frederik, Hounde, Fréjus, Demiral, Furkan, Hassooni, Furqan Ridha Hassooni, Kafa, Gabi, Cárdenas Rivera, Gabriel, Ntwari, Gabriel, Szydlo Shein, Gabriel, Ambriz González, Gabriela, Nita, Gabriela Elisa, Bellio, Gabriele, Moitzi, Gabriele, Urdang, Gabriella, Marom, Gad, Gallo, Gaetano, Luglio, Gaetano, Poillucci, Gaetano, Singh, Gagandeep, Saletta, Gaia, Abouelnagah, Galal, Yarovenko, Galina, Kazobinka, Gallina, Ahmed, Gamal Mutwakil Gamal, Rahman, Ganiyu Adebisi, Smith, Garett, Pillai, Gargi, Saxena, Garima, Gbessi, Gaspard, Nkunguzi, Gaston, Jalal, Gaurav, Chillarge, Gauri, Singh, Gautam, Mevognon, Gedeon, Getachew, Gedion, George, Gejoe, De La Peña González, Gema, Martínez Izquierdo, Gema, Grande, Gennaro, Birikorang, Geoffrey, Weber, Georg F., Singer, Georg, Ansong, George, Bashour, George, Brown, George Darko, Hneino, George, Kavalieratos, George, Kenchadze, George, Nagy, George, Pappas Gogos, George, Skroubis, George, Waiyaki, George, Cox, Georgia, Zeringa, Georgia, De Wee, Georgin, Hart, Georgina, Bekakos, Georgios, Fragulidis, Georgios, Kapogiannatos, Georgios, Karakaidos, Georgios, Kokkinos, Georgios, Kostoulas, Georgios, Koukoulis, Georgios, Peros, Georgios, Rados, Georgios, Tsoulfas, Georgios, Verras, Georgios-Ioannis, Berger, Geraint, Adoro, Gerard Ayuka, Chamoso Mialdea, Gerardo, Palmieri, Gerardo, Procaccini, Gerardo, Steenkamp, Gerhard, Viscido, Germán Rodrigo, Dajti, Gerti, Alemayehu, Getachew, Seyfu, Gezachew, Birqeeq, Ghada, Alsheikh, Ghadeer, Alrayyes, Ghaith, El Hunjul, Ghalib Nashaat, Zaza, Ghayath, Matroud, Ghazlah, Alhadwah, Ghena, Maltinti, Gherardo, Awais, Ghina, Shamsi, Ghina, Calini, Giacomo, Carganico, Giacomo, Zanus, Giacomo, Canu, Gian Luigi, Mendiola, Gian, Ibero Casadiego, Giana Pamela, Cocorullo, Gianfranco, Baronio, Gianluca, Pellino, Gianluca, Zanni, Gianluca, Poto, Gianmario Edoardo, Gravante, Gianpiero, Aduroja, Gideon, Almogy, Gidon, Bond-Smith, Giles, Natchagande, Gilles, Bechara, Gio, Brachini, Gioia, Riccioli, Giordana, Ercolani, Giorgio, Farris, Giorgio, Giraudo, Giorgio, Mammolo, Giovanna, Pavone, Giovanna, Sgarzini, Giovanna, Aprea, Giovanni, Fonsi, Giovanni Battista, Boroni, Giovanni, De Angeli, Giovanni, De Palma, Giovanni Domenico, Emiliani, Giovanni, Grava, Giovanni, Guercio, Giovanni, De Carlo, Giulia, Del Corpo, Giulia, Duranti, Giulia, Galatioto, Giulia, Grassi, Giulia, Graziano, Giulia, Marini, Giulia Maria Francesca, Munzi, Giulia, Tarantino, Giulia, Borda-Luque, Giuliano, Pellicano', Giuseppe Antonino, Canonico, Giuseppe, Carollo, Giuseppe, Ietto, Giuseppe, Palomba, Giuseppe, Pascarella, Giuseppe, Salamone, Giuseppe, Sica, Giuseppe, Sorrentino, Giuseppe, Orlando, Giuseppina, Pignata, Giusto, Pisarevi, Givi, Akcakoca, Gizem, Owusu, Godfred, Yohanna Abrak, Godwin, Kurtoglu, Gokalp Kagan, Kurtoglugk, Gokalp Kagan, Alıcı, Gökhan, Kurtoglu, Goktug Mert, Delgado Hernandez, Gonzalo, Augustin, Goran, Bhat, Gowhar Aziz, Sundaram Venkatesan, Gowtham, Chang, Grace, Eke, Grace, Lee, Grace, Massarra, Grace, Travaglini, Grazia, Scialandrone, Grazisa, Stavrou, Gregor A., Di Franco, Gregorio, Charalambous, Gregory, Christodoulidis, Gregory, Kouraklis, Gregory, Goodwin, Gregory Richard, Devidze, Grigol, Fialho, Guilherme, Santos, Guilherme, Cabezudo, Guillermo, García-Santos, Guillermo, Pou, Guillermo, Romero Reyna, Guillermo, Yanowsky-Reyes, Guillermo, Ozyuksel, Gul, Karadeniz Cakmak, Guldeniz, Kucuk, Gultekin Ozan, Bulbuloglu, Guney Cem, Sarp, Guray, Kaur, Gurleen, Nibogora, Guy Darcy, Hamdan, Gymar, Ogundipe, Habeeb, Yunes, Habib, Ayesh, Hadeel, Al Atassi, Hadi, Jalilehvand, Hadis, Masalma, Hafez, Jafarkhan, Hafis, Shahid, Hafiz Huzaifa, Younus, Hafsa, Al-Derume, Hail, Shames, Haitam, Mimouni, Haithem Ahmed, Aldare, Hajar, Odah Bashi, Hajar Omar, Abusnina, Hajer, Altounsi, Hajir, Qayum, Hajra, Baysal, Hakan, Bolukbasi, Hakan, Yigitbas, Hakan, Alkhatib, Hala, Afzal, Haleema, Mftah, Halima, Oyinlola, Halimah, Tümer, Haluk, Dolo, Hamadoun, Braham, Hamdi, Ozsahin, Hamdi, Abu-Arish, Hamdoon, Al-Aamri, Hamed, Fadlalmola, Hammad Ali, Abu Obead, Hamza, Al-Fahel, Hamza, Al-Zoubi, Hamza, Asaad, Hamza, Ejaz, Hamza, Jaber, Hamza, Bhatti, Hamza Waqar, Mohammadi Sardoo, Hamzeh, Farhat, Hana, Idheiraj, Hanadi, Zwaraa, Hanady, Al Sohabi, Hanan, Basharat, Hanan, Said, Hanan, Al-Abdallat, Haneen, Foad, Haneen, Daaboul, Hanen, Al Qadhi, Hani, Elhallaq, Hani, Alhusaini, Hanin, Lidbetter, Hannah, Reilly, Hannah, Moya- Ambriz, Hannia Betzabeth, Lederhuber, Hans, Fehrer, Hans-Jörg, Xiao, Haotian, Iswariah, Harish, Kaur, Harmeena, Cheema, Harnoor Kaur, Foda, Haroun, Chauhan, Harpreet, Kaur, Harpreet, Sagar, Harry, Unwin, Harry, Kaur, Harsharan, Panga, Harshavardhan, Gupta, Harshit, Prabhakar, Harshit Kumar, Anand, Harshitha, Pahwa, Harvinder Singh, Abbadi, Hasan, Amoudi, Hasan, Zaini, Hasan Hadi Zaini, Škiljo, Hasan, Miyasika, Hasangi, Altabbaa, Hashem, Haj Freej, Hasn, Abdelazim, Hassan, Habiba, Hassan, Kamal, Hassan, Sabir, Hassan, Zaigham, Hassan, Pehlivan, Hatice, Telci, Hatice, Abuobaida, Hayat, Tetley, Heather, Taher, Heba, Aguado López, Héctor, Askarpour, Hedyeh, Sherif Farouk Ahmed Hassan, Heidi, Devesa, Helena, Arbogast, Helmut, Nuñez Del Barrio, Henar, Abiyere, Henry, Delacave, Henry, Rice, Henry E., Pleass, Henry, Bradly, Hera, 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Rugambwa, Jean Paul, Jordaan, Jean- Jacques, Razafindrahita, Jeannie Ba, Do, Jee Eun, Senavirathna, Jeewantha, Kalyanapu, Jeffrey A, Chan, Jeffrey, Ofori, Jeffrey, Otote, Jeffrey, Akiely, Jehad, Cassiano Neves, Jelena, Gillingham, Jemima, Herrera Batres, Jenifer Olga María, Ezeh, Jennifer, Okei, Jennifer, Vu, Jennifer, Guevara, Jenny, Siu, Jenny, Rolinger, Jens, Skaff, Jeolle, Uys, Jernelle, Makama, Jerry Godfrey, Barklimore, Jessica, Dei-Asamoa, Jessica, Jahjah, Jessica, Jones, Jessica, Ng, Jessica, Ricardo, Jéssica, Schembri Higgans, Jessica, You, Jessica, Annan, Jessie, Aguilar, Jesus Antonio, Pizarro Lozano, Jesús, Lim, Jia Hui, Zhu, Jiang, Wang, Jianxue, Abbasy, Jibran, Ugwu, Jideofor, Rathod, Jignesh, Albalushi, Jihan, Najajra, Jinan, Fu, Jing Hui, Tefay, Joan Sia Tan, Domingues, Joana Cristina, Simoes, Joana FF, Figueiredo, Joana, Fontaínhas, Joana, Frazão, Joana, Marques Antunes, Joana, Simoes, Joana, Marx, Joanna Naemi, Dias-Ferreira, João, Fernandes, João, Mendes, João, Pinho, João, Ribeiro, João, Vaz, João, Dominguez, Joaquina, Abutu John, Job, Chen, Joe Jun Qiao, Enaholo, Joel, Alaji, Joelle, Miller, Johanna, Binder, Johannes, Daleku, John, Katogiritis, John, Khoury, John, Anyorigiya, John Noah, Reilly, John, Abebrese, John Tabiri, Ahale, Johnny Lordson, Tabora-Zepeda, Johnny, Barrutia Leonardo, Jon, Demma, Jonathan Abraham, Hong, Jonathan, Chejfec-Ciociano, Jonathan Matias, Oppong, Jonathan, Quansah, Jonathan, Sutcliffe, Jonathan, Taiwo, Jones, Nyamekye - Baidoo, Joojo, Prat-Ortells, Jordi, Dongmo, Jordy, Kleeff, Jorg, Jimenez Flores, Jorge Alberto, Pellecer Cano, Jorge Bernardo, Chóliz, Jorge, Giubi Bobeda, Jorge Eduardo, Escartin, Jorge, Febré, Jorge, Gass, Jörn-Markus, Calvache, Jose A, Guzman Barba, Jose Aldo, Gutiérrez Gómez, José Alonso, Calvache, Jose Andres, Acevedo Parrales, José Danilo, Orozco Navarro, José Esteban, Viñas, José Federico, Gomez, José, Goncalves-Nobre, Jose Guilherme, Valenzuela, José Ignacio, Garcia Galocha, Jose Luis, 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Marcella, Pisano, Marcello, Doniquian, Marcelo Alejandro, Martínez Bareiro, Marcelo Nicolás, Pagani, Marcelo, Scortechini, Marcelo, Carvalho, Márcia, Sánchez Audelo, Marco Antonio, Brizzolari, Marco, Ceresoli, Marco, De Prizio, Marco, Amisano, Marco Francesco, Gramellini, Marco, Marcianò, Marco, Mariani, Marco, Milone, Marco, Montagna, Marco, Piccino, Marco, Santos, Marco, Dyer, Marcus, Kang, Marcus, Mahadi, Mardhiana, Zawadzki, Marek, Yinusa, Margaret, Bernardo, Margarida, Nunes Luís, Margarida, Gambelli, Margherita, Flint, Margot, Aggelidou, Maria, Bequis, Maria Agustina, Sotiriou, Maria Aikaterini, Ñañez, Maria Alejandra, Tahir, Maria Ambreen, Gascón Domínguez, María Ángeles, Asimakidou, Maria, Mourato, Maria Beatriz, Blanco, Maria, Christou, Maria, Coronas Soucheiron, Maria, Pignanelli, Maria Costanza, Kalaydjian, María Cristina, Martí-Ejarque, Maria del Mar, Olmedo Reinoso, María Del Mar, Cebollero, María Del Pilar, Derattani, Maria, Gama Caldeira, Maria Do Carmo, Drogouti, Maria, Gonzalez-Gonzalez, Maria Elena, Muñoz Fernández, María Elena, Muriel, María Emilia, Duran, María Eugenia, Zarate Casas, María Fernanda, Florou, Maria, Piacentini, Maria Gaia, Seixo, Maria Inês, Bellini, Maria Irene, Peña Soria, Maria Jesús, Martínez, María José, Medina, Maria José, Rueda Medécigo, María José, Karakeke, Maria, Kausar, Maria, Kyriazi, Maria, Marqueta De Salas, Maria, Modolo, Maria Marta, Mateu, Maria, Mavri, Maria, El Ghoul Miliotou, Maria Melina, Moreno Gijon, Maria, Papadoliopoulou, Maria, Proclamà, Maria Pia, Picciochi, Maria, Reis, Maria, Rennis, Maria, D'Anna, Maria Rosa, Ruffoli, Maria, Ruiz Soriano, María, Sánchez Ramirez, Maria, Sánchez-Rubio, María, Schüler, Maria, Sotiropoulou, Maria, Barrio Renteria, Maria Teresa, Tsopozidi, Maria, Vasconcelos, Maria, Facchino, Maria Vittoria, Wikar, Maria, Aguilera-Arevalo, Maria-Lorena, Abdu, Mariam, Asarbakhsh, Mariam, Elmiesiry, Mariam, Ashong, Marian Esi, Gomes, Mariana, Capuano, Marianna, Lill, Marianne, Nieto Galvan, 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Nathan, Michael, Maclean, Michael, Nortey, Michael, Pellen, Michael, Pham, Michael, Pitiakoudis, Michael, Singh, Michael Prodip, Spartalis, Michael, Van Der Colf, Michael, Wilson, Michael, Billis, Michail, Karanikas, Michail, Papamichail, Michail, Vailas, Michail, Kisielewski, Michał, Kusiński, Michał, Nycz, Michał, Święch, Michał, Fagbayimu, Micheal, Adamina, Michel, Fiogbe, Michel, Prudhomme, Michel, Angelucci, Michela, Campanelli, Michela, Cricrì, Michele, Grande, Michele, Manigrasso, Michele, Scopelliti, Michele, George, Michelle, Mozel, Michelle, Galasyuk, Mick, Chevallay, Mickael, Giuliano, Micol, Dobón Rascón, Miguel Ángel, Fernandez Romero, Miguel Angel, García Ureña, Miguel Ángel, Zaragoza Mendieta, Miguel Ángel, Bejarano Serrano, Miguel, Brito, Miguel, Calderon, Miguel, Jurado Román, Miguel, Palas, Miguel, Li Valencia, Miguel Roberto, Sebastián-Mendoza, Miguel-Julián, Muresan, Mihai-Stefan, Slavchev, Mihail, Agapov, Mikhail, Milentijević, Milica, Catterall, Millie, 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Abosedra, Mohammed, Sarker, Mohammed Abu Kawsar, Abudabbous, Mohammed, Abuwarda, Mohammed, Elgak, Mohammed Ahmed, Al Hinai, Mohammed, Al Zebda, Mohammed, Al-Shehari, Mohammed, Alharthi, Mohammed, Ali, Mohammed, Ismael Alamin, Mohammed Ali, Alqadasi, Mohammed, Alshanwani, Mohammed, Alshehri, Mohammed, Asaad, Mohammed, Bashir, Mohammed, Bohlala, Mohammed, Meghaizerou, Mohammed El Amine, Albanna, Mohammed Emad Hashem, Ghunaim, Mohammed, Goga, Mohammed, Hajhamad, Mohammed, Hamada Takrouney, Mohammed, Hammoda, Mohammed, Hamoud Almahly, Mohammed, Muragi, Mohammed, Mohammed, Mohammed Mustafa Hassan, Obaid, Mohammed, Omar, Mohammed, Said, Mohammed, Salah, Mohammed, Saleh Khatab, Mohammed, Aliyu, Mohammed Salele, Shakhshir, Mohammed, Sheriff, Mohammed, Tageldin, Mohammed, Abdelfattah, Mohanad, Daher, Mohanad, Lotfy, Mohanad, Alqedrh, Mohannad, Nasani, Mohannad, Mohd Shah, Mohd Shahrulsalam, Madany, Mohie El-Din Mostafa, Mobolaji-Ojibara, Mojisola, Nkogatse, Moleseng, Alazabi, Mona, Gupta, 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Abubasheer, Tareq, Alhusban, Tariq, Yılmaz, Tarık Emre, Aloqaili, Tasneem, Aldirawi, Tayef, Karahasanoğlu, Tayfun, Gülşen, Taygun, Jemal, Tebarek, Nadeem, Tehmina, Singh, Tejinder Paul, Alinger, Temsula, Longkumer, Temsutoshi, Lo, Terence, Gimenez Maurel, Teresa, Uprak, Tevfik Kıvılcım, Petropoulou, Thalia, Rawther, Thampi, Techapongsatorn, Thawin, Manickam, Thendral, Padioti, Theodora, Kozonis, Theodoros, Sidiropoulos, Theodoros, Tsirlis, Theodoros, Theodosopoulos, Theodosios, Hessou, Thierry Kinnongni, Uiyapat, Thitapon, Agyen, Thomas, Harris, Thomas, Hugh, Thomas J, Jorgensen, Thomas W., Theivendrampillai, Thrshegan, Pham, Thuy Vy, Branco, Tiago, Nagwamutse, Tijjani Nasiru, Tony V, Tina, Devabalan Koil, Titus, Pilia, Tiziana, Abdulmola, Tmador Mahmed Ali, Oyeyemi, Tobiloba, Kebede, Tolera, Ibarra-Hurtado, Tomás Ramón, Reichelt, Tomas, Gach, Tomasz, Stefura, Tomasz, Wojewoda, Tomasz, Soric, Tomislav, Risteski, Toni, Tridip, Tridip Dutta Baruah, Yotsov, Tsanko, Doma Bhutia, Tshering, Girma, Tsion, Kwan, Tsun Yu, Ivanov, Tsvetomir, Iahmo, TT, Ashkar, Tuleen, Mabogoane, Tumi, Olobatoke, Tunde, Sholadoye, Tunde T., Mishra, Tushar Subhadarshan, Parker, Tyla, Ezomike, Uchechukwu, Dilibe, Uchenna, Kumbhar, Uday, Una, Uduak-Abasi, Grossi, Ugo, Ezidiegwu, Ugochukwu, Edith, Ugwuoke, Daspal, Ujjwal, Kalu, Ukoha Agwu, Dietz, Ulrich, Ronellenfitsch, Ulrich, Wirth, Ulrich, Abdullah, Umar, Rivolta, Umberto, Jayarajah, Umesh, Kanyan Kassim, Umu-Hera, Govindan, Unnikrishnan, Fernandes, Urânia, Akram, Usman, Mohammed Bello, Usman, Omara, Usra, Naidoo, Uvarasen, Mahendravarman, Vaishnaivy, Negoita, Valentina Madalina, Mariottini, Valentina, Murzi, Valentina, Zucchini, Valentina, Agbakwuru, Valentine, Armenta Tapia, Valeria Estefania, Gentilino, Valerio, Borgogni, Vanessa, Ng, Vanessa, Wolfschluckner, Vanessa, Silvestri, Vania, Žufić, Vanja, Gunasaegaram, Varman, Kamalathevan, Vasan, Pillay, Vasanthan, Neykov, Vasil, Kalles, Vasileios, Mousafeiris, Vasileios, Papadopoulos, Vasileios, Tsaousis, Vasileios, Tselepidis, Vasileios, Vougas, Vasileios, Georgilaki, Vasiliki, Nikolaou, Vasiliki, Themelidi, Vasiliki, Manchev, Vassil, Ioannou, Veatriki, Jha, Vedant Shekhar, Dragisic, Vedran, Sutharshan, Vengadasalam, Alonso, Veronica, Brocco, Veronica, Ongil Rodríguez, Verónica, Schirinzi, Veronica, Budyakova, Veronika, Naunova, Vesna, Panduro-Correa, Vicky, Ruiz López, Víctor Andrés, Bill, Victor, Dassah, Victor, Gonzabay, Víctor Eduardo, Etwire, Victor, Modekwe, Victor, Serna-Alarcon, Victor, De Donato, Victor Ugo, Duque Mallén, Victoria, Liu, Victoria, Sharma, Vidushi, Kumar, Vijaya, Muralidharan, Vijayaragavan, Kakotkin, Viktor, Enemuo, Vincent, Kudoh, Vincent, Osoka, Vincent, Siepaal, Vincent, Granata, Vincenza, Dinuzzi, Vincenza Paola, Lizzi, Vincenzo, Ricchiuti, Vincenzo, Mosca, Vinicio, Kanna D, Vinoth, Nair, Vipin Venugopal, Ledda, Virginia, Michael, Vishal, Singh, Vishavdeep, Govindasamy, Vishendran, Kollengode, Viswanathan V, Giordano, Vittoria, Morinelli, Vittoria, Lin, Vivian, Cuk, Vladica, Cijan, Vladimir, Çalik, Volkan, Bakshi, Vrushank, Ten, Vyacheslav, Ratheesh, Vysakh, Alsado, Wael, Mayo, Wafik, Yang, Wah, Rehman, Wajeeh Ur, Abbas, Walaa, Al-Khyatt, Waleed, Mabood, Waleed, Santucci, Walter, Yew, Wan Ting, Tahir, Warda, De Silva, Warusha Dhammika Dulantha, Wijenayake, Wasantha, Almadhoun, Waseem J.N., Alhroub, Wasef, Ebrahim, Wesam, Jabłoński, Wiktor, Krawczyk, Wiktor, Bhatti, William, Lai, William Kwan Ho, Petrushnko, Wilson, Afedo, Wisdom, Kasetsermwiriya, Wisit, Serednicki, Wojciech, Wysocki, Wojciech, Zerefa, Wondwossen Amtataw, Vagena, Xanthoula, Tarrado, Xavier, Papazarkadas, Xenofon, Po, Xiang Yuen, Ouadi, Yacine, Myla, Yacob, Haido, Yacoub, Hasan, Yafea, Karataş, Yağmur, Carpio Colmenares, Yahaira, Galvañ Félix, Yaiza, Balogun, Yakub Lekan, Maktabi, Yaman, Nerabani, Yaman, Fulgence, Yamuremye, De Silva, Yannick, Asar, Yara, Samer Morsy, Yara, Ghaleb, Yasameen Saif Saeed Mohammed, Vashishth, Yash, M S, Yashas, Manickchund, Yashoda, Sakaray, Yashwant, Kara, Yasin, Tosun, Yasin, Zwain, Yasir, Farag, Yasmeen, Jedidi, Yasmine, Seada, Yasmine, Aldebasi, Yasser, Ashour, Yasser, Badr, Yassin, Sarpong, Yaw, Alawneh, Yazan, Aung, Yee Lay, Orabi, Yehia, Lam, Yick Ho, Şen, Yigit Kaan, Koyluoglu, Yilmaz Onat, Huang, Yining, Mintz, Yoav, Perez, Yocarli, Chamara, Yohan, Melkamu, Yohannes, Maestre González, Yolanda, Dean, Yomna, Metaferia, Yonas Yilma, Malki, Yosra, Mohamed, Younis, A. Omar, Yousef, Alhammoud, Yousef, Allaoua, Yousef, Tanas, Yousef, El Okazy, Youssef, Kerolous, Youssef, Mohamed, Youssef, Al-Junaidi, Youssuf, Lakdawala, Yousuf, Lu, Yuann, Asano, Yukio, Altinel, Yuksel, Aktimur, Yunus Emre, Fishman, Yuri, Kudryavcev, Yurii, Tandoğan, Yusuf Iskender, Razafimandimby, Yves Michaël, Adofo-Asamoah, Yvonne, Şenol, Zafer, Odeh, Zahra, Benamrouche, Zahra Rayane, Alkhaier, Zahraa, Al-Sheikh Ali, Zaid, Zaher, Zain Aldin, Alnajjar, Zaina, Al-Balushi, Zainab, Alkhuzaie, Zainab, Khraim, Zakaria, Toutounji, Zakaria, Djama, Zakarya, Farraj, Zamil, Shah, Zamir Ahmad, Khan, Zara, Khan, Zarnigar, Abo Alarous, Zayn Alabden, Asaad, Zaynab, Demetrashvili, Zaza, Lorenc, Zbigniew, Brekalo, Zdrinko, Hannouneh, Zein Alabdin, Robertson, Zelda, Bady, Zeyad, Durna, Zeynep, Wong, Zhen Yu, Fozo, Zien Alabdin, Klib, Zienab, Chin, Ziling, Tamou, Zime Farid, Johnson, Zina, Shabello, Ziyad, Orzeszko, Zofia, Aljalabi, Zohal, Al-Azher El-Hamel, Zohour, Karampotaki, Zoi Rafaila, Valera Sanchez, Zoraida, Matkovic, Zoran, Azhar, Zubair, Qureshi, Zubaria, Correa López, Zulema Margarita, Balciscueta, Zutoia, Musilová, Zuzana, Katusic, Zvonimir, Osama, Zyad, and Dauksa, Zygimantas

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2024
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44. The impact of inversions across 33,924 families with rare disease from a national genome sequencing project

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Pagnamenta, Alistair T., Yu, Jing, Walker, Susan, Noble, Alexandra J., Lord, Jenny, Dutta, Prasun, Hashim, Mona, Camps, Carme, Green, Hannah, Devaiah, Smrithi, Nashef, Lina, Parr, Jason, Fratter, Carl, Ibnouf Hussein, Rana, Lindsay, Sarah J., Lalloo, Fiona, Banos-Pinero, Benito, Evans, David, Mallin, Lucy, Waite, Adrian, Evans, Julie, Newman, Andrew, Allen, Zoe, Perez-Becerril, Cristina, Ryan, Gavin, Hart, Rachel, Taylor, John, Bedenham, Tina, Clement, Emma, Blair, Ed, Hay, Eleanor, Forzano, Francesca, Higgs, Jenny, Canham, Natalie, Majumdar, Anirban, McEntagart, Meriel, Lahiri, Nayana, Stewart, Helen, Smithson, Sarah, Calpena, Eduardo, Jackson, Adam, Banka, Siddharth, Titheradge, Hannah, McGowan, Ruth, Rankin, Julia, Shaw-Smith, Charles, Evans, D. Gareth, Burghel, George J., Smith, Miriam J., Anderson, Emily, Madhu, Rajesh, Firth, Helen, Ellard, Sian, Brennan, Paul, Anderson, Claire, Taupin, Doug, Rogers, Mark T., Cook, Jackie A., Durkie, Miranda, East, James E., Fowler, Darren, Wilson, Louise, Igbokwe, Rebecca, Gardham, Alice, Tomlinson, Ian, Baralle, Diana, Uhlig, Holm H., and Taylor, Jenny C.

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2024
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45. Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases

Author

Pagnamenta, Alistair T., Camps, Carme, Giacopuzzi, Edoardo, Taylor, John M., Hashim, Mona, Calpena, Eduardo, Kaisaki, Pamela J., Hashimoto, Akiko, Yu, Jing, Sanders, Edward, Schwessinger, Ron, Hughes, Jim R., Lunter, Gerton, Dreau, Helene, Ferla, Matteo, Lange, Lukas, Kesim, Yesim, Ragoussis, Vassilis, Vavoulis, Dimitrios V., Allroggen, Holger, Ansorge, Olaf, Babbs, Christian, Banka, Siddharth, Baños-Piñero, Benito, Beeson, David, Ben-Ami, Tal, Bennett, David L., Bento, Celeste, Blair, Edward, Brasch-Andersen, Charlotte, Bull, Katherine R., Cario, Holger, Cilliers, Deirdre, Conti, Valerio, Davies, E. Graham, Dhalla, Fatima, Dacal, Beatriz Diez, Dong, Yin, Dunford, James E., Guerrini, Renzo, Harris, Adrian L., Hartley, Jane, Hollander, Georg, Javaid, Kassim, Kane, Maureen, Kelly, Deirdre, Kelly, Dominic, Knight, Samantha J. L., Kreins, Alexandra Y., Kvikstad, Erika M., Langman, Craig B., Lester, Tracy, Lines, Kate E., Lord, Simon R., Lu, Xin, Mansour, Sahar, Manzur, Adnan, Maroofian, Reza, Marsden, Brian, Mason, Joanne, McGowan, Simon J., Mei, Davide, Mlcochova, Hana, Murakami, Yoshiko, Németh, Andrea H., Okoli, Steven, Ormondroyd, Elizabeth, Ousager, Lilian Bomme, Palace, Jacqueline, Patel, Smita Y., Pentony, Melissa M., Pugh, Chris, Rad, Aboulfazl, Ramesh, Archana, Riva, Simone G., Roberts, Irene, Roy, Noémi, Salminen, Outi, Schilling, Kyleen D., Scott, Caroline, Sen, Arjune, Smith, Conrad, Stevenson, Mark, Thakker, Rajesh V., Twigg, Stephen R. F., Uhlig, Holm H., van Wijk, Richard, Vona, Barbara, Wall, Steven, Wang, Jing, Watkins, Hugh, Zak, Jaroslav, Schuh, Anna H., Kini, Usha, Wilkie, Andrew O. M., Popitsch, Niko, and Taylor, Jenny C.

Published
2023
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47. Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders

Author

Gracia-Diaz, Carolina, Zhou, Yijing, Yang, Qian, Maroofian, Reza, Espana-Bonilla, Paula, Lee, Chul-Hwan, Zhang, Shuo, Padilla, Natàlia, Fueyo, Raquel, Waxman, Elisa A., Lei, Sunyimeng, Otrimski, Garrett, Li, Dong, Sheppard, Sarah E., Mark, Paul, Harr, Margaret H., Hakonarson, Hakon, Rodan, Lance, Jackson, Adam, Vasudevan, Pradeep, Powel, Corrina, Mohammed, Shehla, Maddirevula, Sateesh, Alzaidan, Hamad, Faqeih, Eissa A., Efthymiou, Stephanie, Turchetti, Valentina, Rahman, Fatima, Maqbool, Shazia, Salpietro, Vincenzo, Ibrahim, Shahnaz H., di Rosa, Gabriella, Houlden, Henry, Alharbi, Maha Nasser, Al-Sannaa, Nouriya Abbas, Bauer, Peter, Zifarelli, Giovanni, Estaras, Conchi, Hurst, Anna C. E., Thompson, Michelle L., Chassevent, Anna, Smith-Hicks, Constance L., de la Cruz, Xavier, Holtz, Alexander M., Elloumi, Houda Zghal, Hajianpour, M J, Rieubland, Claudine, Braun, Dominique, Banka, Siddharth, French, Deborah L., Heller, Elizabeth A., Saade, Murielle, Song, Hongjun, Ming, Guo-li, Alkuraya, Fowzan S., Agrawal, Pankaj B., Reinberg, Danny, Bhoj, Elizabeth J., Martínez-Balbás, Marian A., and Akizu, Naiara

Published
2023
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49. Heterozygous loss-of-function SMC3 variants are associated with variable growth and developmental features

Author

Morad Ansari, Kamli N.W. Faour, Akiko Shimamura, Graeme Grimes, Emeline M. Kao, Erica R. Denhoff, Ana Blatnik, Daniel Ben-Isvy, Lily Wang, Benjamin M. Helm, Helen Firth, Amy M. Breman, Emilia K. Bijlsma, Aiko Iwata-Otsubo, Thomy J.L. de Ravel, Vincent Fusaro, Alan Fryer, Keith Nykamp, Lara G. Stühn, Tobias B. Haack, G. Christoph Korenke, Panayiotis Constantinou, Kinga M. Bujakowska, Karen J. Low, Emily Place, Jennifer Humberson, Melanie P. Napier, Jessica Hoffman, Jane Juusola, Matthew A. Deardorff, Wanqing Shao, Shira Rockowitz, Ian Krantz, Maninder Kaur, Sarah Raible, Victoria Dortenzio, Sabine Kliesch, Moriel Singer-Berk, Emily Groopman, Stephanie DiTroia, Sonia Ballal, Siddharth Srivastava, Kathrin Rothfelder, Saskia Biskup, Jessica Rzasa, Jennifer Kerkhof, Haley McConkey, Bekim Sadikovic, Sarah Hilton, Siddharth Banka, Frank Tüttelmann, Donald F. Conrad, Anne O’Donnell-Luria, Michael E. Talkowski, David R. FitzPatrick, and Philip M. Boone

Subjects
Cornelia de Lange syndrome, SMC3, loss-of-function, cohesin, CdLS3, LoF, Genetics, QH426-470
Abstract

Summary: Heterozygous missense variants and in-frame indels in SMC3 are a cause of Cornelia de Lange syndrome (CdLS), marked by intellectual disability, growth deficiency, and dysmorphism, via an apparent dominant-negative mechanism. However, the spectrum of manifestations associated with SMC3 loss-of-function variants has not been reported, leading to hypotheses of alternative phenotypes or even developmental lethality. We used matchmaking servers, patient registries, and other resources to identify individuals with heterozygous, predicted loss-of-function (pLoF) variants in SMC3, and analyzed population databases to characterize mutational intolerance in this gene. Here, we show that SMC3 behaves as an archetypal haploinsufficient gene: it is highly constrained against pLoF variants, strongly depleted for missense variants, and pLoF variants are associated with a range of developmental phenotypes. Among 14 individuals with SMC3 pLoF variants, phenotypes were variable but coalesced on low growth parameters, developmental delay/intellectual disability, and dysmorphism, reminiscent of atypical CdLS. Comparisons to individuals with SMC3 missense/in-frame indel variants demonstrated an overall milder presentation in pLoF carriers. Furthermore, several individuals harboring pLoF variants in SMC3 were nonpenetrant for growth, developmental, and/or dysmorphic features, and some had alternative symptomatologies with rational biological links to SMC3. Analyses of tumor and model system transcriptomic data and epigenetic data in a subset of cases suggest that SMC3 pLoF variants reduce SMC3 expression but do not strongly support clustering with functional genomic signatures of typical CdLS. Our finding of substantial population-scale LoF intolerance in concert with variable growth and developmental features in subjects with SMC3 pLoF variants expands the scope of cohesinopathies, informs on their allelic architecture, and suggests the existence of additional clearly LoF-constrained genes whose disease links will be confirmed only by multilayered genomic data paired with careful phenotyping.

Published
2024
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50. Polysalicylic Acid Polymer Microparticle Decoys Therapeutically Treat Acute Respiratory Distress Syndrome

Author

Brannon, Emma R, Kelley, William J, Newstead, Michael W, Banka, Alison L, Uhrich, Kathryn E, O'Connor, Colleen E, Standiford, Theodore J, and Eniola‐Adefeso, Omolola

Subjects
Acute Respiratory Distress Syndrome, Rare Diseases, Lung, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Respiratory, Good Health and Well Being, Acute Lung Injury, Animals, Mice, Neutrophil Infiltration, Polymers, Respiratory Distress Syndrome, Salicylic Acid, inflammation, lung injury, microparticles, neutrophils, phagocytosis, Medicinal and Biomolecular Chemistry, Biomedical Engineering, Medical Biotechnology
Abstract

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) remain problematic due to high mortality rates and lack of effective treatments. Neutrophilic injury contributes to mortality in ALI/ARDS. Here, technology for rapid ARDS intervention is developed and evaluated, where intravenous salicylic acid-based polymer microparticles, i.e., Poly-Aspirin (Poly-A), interfere with neutrophils in blood, reducing lung neutrophil infiltration and injury in vivo in mouse models of ALI/ARDS. Importantly, Poly-A particles reduce multiple inflammatory cytokines in the airway and bacterial load in the bloodstream in a live bacteria lung infection model of ARDS, drastically improving survival. It is observed that phagocytosis of the Poly-A microparticles, with salicylic acid in the polymer backbone, alters the neutrophil surface expression of adhesion molecules, potentially contributing to their added therapeutic benefits. Given the proven safety profile of the microparticle degradation products-salicylic acid and adipic acid-it is anticipated that the Poly-A particles represent a therapeutic strategy in ARDS with a rare opportunity for rapid clinical translation.

Published
2022

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