4 results on '"Banjoko B"'
Search Results
2. MICA, HLA-B haplotypic variation in five population groups of sub-Saharan African ancestry
- Author
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Marcus Inyama, A Essiet, Patricia A. Fraser, Dong-Feng Chen, Mohseni M, Deborah A. Boggs, Adewole T, Wei Tian, Banjoko B, Wei-Zi Ding, Fritz R, Gabriel Uko, and Lyle J. Palmer
- Subjects
Linkage disequilibrium ,Immunology ,Population ,Population genetics ,Black People ,Biology ,Linkage Disequilibrium ,Gene Frequency ,Trinucleotide Repeats ,Genetic variation ,Genetics ,Humans ,Allele ,education ,Allele frequency ,Genetics (clinical) ,Africa South of the Sahara ,Alleles ,education.field_of_study ,Haplotype ,Histocompatibility Antigens Class I ,Genetic Variation ,HLA-B ,stomatognathic diseases ,Genetics, Population ,Haplotypes ,HLA-B Antigens ,Boston - Abstract
The human major histocompatibility complex (MHC) class I chain-related gene A (MICA), located 46 kb centromeric to HLA-B, encodes a stress-inducible protein, which is a ligand for the NKG2D receptor. In addition to its primary role in immune surveillance, data suggest that MICA is involved in the immune response to transplants and in susceptibility to some diseases. In this study, 152 subjects from the Yoruba (n=74), Efik (n=32), and Igbo (n=46) tribes of southern Nigeria, 39 nationwide African-American stem cell donors, and 60 African-American individuals residing in the metropolitan Boston area were studied for MICA, HLA-B allelic variation, haplotypic diversity, and linkage disequilibrium (LD). MICA and HLA-B exhibited a high degree of genetic diversity among the populations studied. In particular, MICA allele and HLA-B-MICA haplotype frequencies and LD in the Efik and Igbo tribes were significantly different from the other study groups. HLA-B and MICA loci demonstrated significant global LD in all five populations (P-values &
- Published
- 2003
3. Stress, Illness Perceptions, Behaviors, and Healing in Venous Leg Ulcers: Findings From a Prospective Observational Study.
- Author
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Walburn J, Weinman J, Norton S, Hankins M, Dawe K, Banjoko B, and Vedhara K
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- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Prospective Studies, Depression psychology, Health Knowledge, Attitudes, Practice, Outcome Assessment, Health Care, Stress, Psychological psychology, Varicose Ulcer psychology, Varicose Ulcer therapy
- Abstract
Objective: The aim of the study was to investigate the impact of stress, illness perceptions, and behaviors on healing of venous leg ulcers., Methods: A prospective observational study of 63 individuals for 24 weeks investigated possible psychosocial predictors of healing. There were two indices of healing: rate of change in ulcer area and number of weeks to heal. Psychological variables were assessed at baseline using self-report measures (Perceived Stress Scale, Hospital Anxiety and Depression Scale, Revised Illness Perception Questionnaire, adapted Summary of Diabetes Self-Care Activities, Adherence Questionnaire, and Short-Form Health Survey)., Results: Controlling for sociodemographic and clinical variables, for the 24 weeks, a slower rate of change in ulcer area was predicted by greater stress (standardized β = -0.61, p = .008), depression (standardized β = -0.51, p = .039), and holding negative perceptions or beliefs about the ulcer (standardized β = -1.4, p = .045). By 24 weeks, 69% of ulcers had closed. A more negative emotional response to the ulcer at baseline (i.e., emotional representation of the ulcer) was associated with a greater number of weeks to heal (hazard ratio [HR] = 0.63, 95% confidence interval [CI] = 0.41-0.95, p = .028). Higher educational attainment (HR = 3.22, 95% CI = 1.37-7.55, p = .007) and better adherence to compression bandaging (HR = 1.41, 95% CI = 1.06-1.88, p = .019) were associated with fewer weeks to heal. No other psychosocial variable (stress, perceptions about the ulcer, health behaviors) predicted weeks to heal., Conclusions: Alongside ulcer-related predictors, psychological and sociodemographic factors were associated with healing. Future research should explore mediating mechanisms underlying these associations and develop interventions to target these variables.
- Published
- 2017
- Full Text
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4. Radon level in a Nigerian University Campus.
- Author
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Afolabi OT, Esan DT, Banjoko B, Fajewonyomi BA, Tobih JE, and Olubodun BB
- Subjects
- Adult, Aged, Environmental Exposure, Humans, Middle Aged, Nigeria, Air Pollutants, Radioactive analysis, Air Pollution, Indoor analysis, Radon analysis, Universities
- Abstract
Background: Globally, radon is a natural contaminant that affects indoor air quality. Several epidemiological studies have implicated high radon levels in the causality of lung cancer. The study therefore determined the environmental level of radon in selective offices in the Obafemi Awolowo University, Ile-Ife. The study employed a descriptive cross-sectional design. A Pro 3-series radon detector was used to determine the radon levels in randomly selected offices. The instrument was set-up in each office and after 48 h, reading was taken and recorded on a proforma data sheet. The structural characteristics of the offices were also assessed by observation., Results: The result revealed that the radon level obtained in the sampled offices ranged from 0.0 to 5.3 pCi/L (196 Bq/m(3)). The median concentration of radon obtained from sampled offices was 0.9 pCi/L. Almost all (95 %) of the offices had radon levels within the 'permissible' reference level recommended by World Health Organization. Radon levels also showed a statistically significant decline with height of office building with the mean concentration of radon in offices located on the basement, ground floor and first floor being 1.54 ± 1.32, 0.99 ± 0.56, 0.63 ± 0.41 pCi/L respectively, (F statistic 5.8, p < 0.001)., Conclusion: The radon levels obtained in most assessed offices in Obafemi Awolowo University were found to be within the permissible reference levels. Mitigation measures should be put in place in the few offices above permissible levels.
- Published
- 2015
- Full Text
- View/download PDF
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