Author: "Bancroft, Gregory" - Searchworks@Jio Institute Digital Library Search Results

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369 results on '"Bancroft, Gregory"'

1. Glibenclamide alters interleukin-8 and interleukin-1β of primary human monocytes from diabetes patients against Mycobacterium tuberculosis infection

Author: Kewcharoenwong, Chidchamai, Saenwongsa, Wipawee, Willcocks, Samuel J., Bancroft, Gregory J., Fletcher, Helen A., and Lertmemongkolchai, Ganjana
Published: 2020
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2. Burkholderia pseudomallei and Burkholderia mallei vaccines: Are we close to clinical trials?

Author: Titball, Richard W., Burtnick, Mary N., Bancroft, Gregory J., and Brett, Paul
Published: 2017
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3. Phenotypic and Functional Characterization of Human Memory T Cell Responses to Burkholderia pseudomallei

Author: Tippayawat, Patcharaporn, Saenwongsa, Wipawee, Mahawantung, Jirawan, Suwannasaen, Duangchan, Chetchotisakd, Ploenchan, Limmathurotsakul, Direk, Peacock, Sharon J, Felgner, Philip L, Atkins, Helen S, Titball, Richard W, Bancroft, Gregory J, and Lertmemongkolchai, Ganjana
Subjects: gamma-interferon, ifn-gamma, provides protection, severe melioidosis, adaptive immunity, secretion system, murine model, risk-factors, infection, identification
Abstract: Background: Infection with the Gram-negative bacterium Burkholderia pseudomallei is an important cause of community-acquired lethal sepsis in endemic regions in southeast Asia and northern Australia and is increasingly reported in other tropical areas. In animal models, production of interferon-gamma (IFN-gamma) is critical for resistance, but in humans the characteristics of IFN-gamma production and the bacterial antigens that are recognized by the cell-mediated immune response have not been defined. Methods: Peripheral blood from 133 healthy individuals who lived in the endemic area and had no history of melioidosis, 60 patients who had recovered from melioidosis, and 31 other patient control subjects were stimulated by whole bacteria or purified bacterial proteins in vitro, and IFN-gamma responses were analyzed by ELISPOT and flow cytometry. Findings: B. pseudomallei was a potent activator of human peripheral blood NK cells for innate production of IFN-gamma. In addition, healthy individuals with serological evidence of exposure to B. pseudomallei and patients recovered from active melioidosis developed CD4(+) (and CD8(+)) T cells that recognized whole bacteria and purified proteins LolC, OppA, and PotF, members of the B. pseudomallei ABC transporter family. This response was primarily mediated by terminally differentiated T cells of the effector-memory (T(EMRA)) phenotype and correlated with the titer of anti-B. pseudomallei antibodies in the serum. Conclusions: Individuals living in a melioidosis-endemic region show clear evidence of T cell priming for the ability to make IFN-gamma that correlates with their serological status. The ability to detect T cell responses to defined B. pseudomallei proteins in large numbers of individuals now provides the opportunity to screen candidate antigens for inclusion in protein or polysaccharide-conjugate subunit vaccines against this important but neglected disease.
Published: 2009

4. Mineralized Matrix Deposition by Marrow Stromal Osteoblasts in 3D Perfusion Culture Increases with Increasing Fluid Shear Forces

Author: Sikavitsas, Vassilios I., Bancroft, Gregory N., Holtorf, Heidi L., Jansen, John A., and Mikos, Antonios G.
Published: 2003

5. A proteasome inhibitor produced by Burkholderia pseudomallei modulates intracellular growth

Author: Wagley, Sariqa, Vanaporn, Muthita, Rinchai, Darawan, Conejero, Laura, Lertmemongkolchai, Ganjana, Bancroft, Gregory J., and Titball, Richard W.
Published: 2017
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6. Fluid Flow Increases Mineralized Matrix Deposition in 3D Perfusion Culture of Marrow Stromal Osteoblasts in a Dose-Dependent Manner

Author: Bancroft, Gregory N., Sikavitsas, Vassilios I., van den Dolder, Juliette, Sheffield, Tiffany L., Ambrose, Catherine G., Jansen, John A., and Mikos, Antonios G.
Published: 2002

7. Immune responses in beta-thalassaemia: heme oxygenase 1 reduces cytokine production and bactericidal activity of human leucocytes

Author: Nithichanon, Arnone, Tussakhon, Inthira, Samer, Waraporn, Kewcharoenwong, Chidchamai, Ato, Manabu, Bancroft, Gregory J., and Lertmemongkolchai, Ganjana
Published: 2020
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8. Identification of an OmpW homologue in Burkholderia pseudomallei, a protective vaccine antigen against melioidosis

Author: Casey, William T., Spink, Natasha, Cia, Felipe, Collins, Cassandra, Romano, Maria, Berisio, Rita, Bancroft, Gregory J., and McClean, Siobhán
Published: 2016
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9. Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence

Author: Butt, Aaron, Halliday, Nigel, Williams, Paul, Atkins, Helen S., Bancroft, Gregory J., and Titball, Richard W.
Published: 2016
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10. Immunisation with proteins expressed during chronic murine melioidosis provides enhanced protection against disease

Author: Champion, Olivia L., Gourlay, Louise J., Scott, Andrew E., Lassaux, Patricia, Conejero, Laura, Perletti, Lucia, Hemsley, Claudia, Prior, Joann, Bancroft, Gregory, Bolognesi, Martino, and Titball, Richard W.
Published: 2016
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11. Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system

Author: Bottai, Daria, Frigui, Wafa, Clark, Simon, Rayner, Emma, Zelmer, Andrea, Andreu, Nuria, de Jonge, Marien I., Bancroft, Gregory J., Williams, Ann, Brodin, Priscille, and Brosch, Roland
Published: 2015
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12. Deletion of zmp1 improves Mycobacterium bovis BCG-mediated protection in a guinea pig model of tuberculosis

Author: Sander, Peter, Clark, Simon, Petrera, Agnese, Vilaplana, Cristina, Meuli, Michael, Selchow, Petra, Zelmer, Andrea, Mohanan, Deepa, Andreu, Nuria, Rayner, Emma, Dal Molin, Michael, Bancroft, Gregory J., Johansen, Pål, Cardona, Pere-Joan, Williams, Ann, and Böttger, Erik C.
Published: 2015
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13. Combining Vaccination and Postexposure CpG Therapy Provides Optimal Protection Against Lethal Sepsis in a Biodefense Model of Human Melioidosis

Author: Easton, Anna, Haque, Ashraful, Chu, Karen, Patel, Natasha, Lukaszewski, Roman A., Krieg, Arthur M., Titball, Richard W., and Bancroft, Gregory J.
Published: 2011
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14. Human Immune Responses to Burkholderia pseudomallei Characterized by Protein Microarray Analysis

Author: Suwannasaen, Duangchan, Mahawantung, Jirawan, Chaowagul, Wipada, Limmathurotsakul, Direk, Felgner, Philip L., Davies, Huw, Bancroft, Gregory J., Titball, Richard W., and Lertmemongkolchai, Ganjana
Published: 2011
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15. Low-Dose Exposure of C57BL/6 Mice to Burkholderia pseudomallei Mimics Chronic Human Melioidosis

Author: Conejero, Laura, Patel, Natasha, de Reynal, Melanie, Oberdorf, Sara, Prior, Joanne, Felgner, Philip L., Titball, Richard W., Salguero, Francisco J., and Bancroft, Gregory J.
Published: 2011
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16. A Critical Role for Neutrophils in Resistance to Experimental Infection with Burkholderia pseudomallei

Author: Easton, Anna, Haque, Ashraful, Chu, Karen, Lukaszewski, Roman, and Bancroft, Gregory J.
Published: 2007

17. A Live Experimental Vaccine against Burkholderia pseudomallei Elicits CD4⁺ T Cell-Mediated Immunity, Priming T Cells Specific for 2 Type III Secretion System Proteins

Author: Haque, Ashraful, Chu, Karen, Easton, Anna, Stevens, Mark P., Galyov, Edouard E., Atkins, Tim, Titball, Rick, and Bancroft, Gregory J.
Published: 2006

18. Role of T Cells in Innate and Adaptive Immunity against Murine Burkholderia pseudomallei Infection

Author: Haque, Ashraful, Easton, Anna, Smith, Debbie, O'Garra, Anne, Van Rooijen, Nico, Lertmemongkolchai, Ganjana, Titball, Richard W., and Bancroft, Gregory J.
Published: 2006

19. Enhanced Protection against Tuberculosis by Vaccination with Recombinant Mycobacterium microti Vaccine That Induces T Cell Immunity against Region of Difference 1 Antigens

Author: Brodin, Priscille, Majlessi, Laleh, Brosch, Roland, Smith, Debbie, Bancroft, Gregory, Clark, Simon, Williams, Ann, Leclerc, Claude, and Cole, Stewart T.
Published: 2004

20. Increased Susceptibility to Cytomegalovirus Infection in Beige Mutant Mice

Author: Shellam, Geoffrey R., Allan, Jane E., Papadimitriou, John M., and Bancroft, Gregory J.
Published: 1981

21. The case for hypervirulence through gene deletion in Mycobacterium tuberculosis

Author: ten Bokum, Annemieke M.C., Movahedzadeh, Farahnaz, Frita, Rosangela, Bancroft, Gregory J., and Stoker, Neil G.
Published: 2008
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