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1. Traduction et republication de « Recommandations de l’EAACI sur le diagnostic de l’allergie alimentaire médiée par les IgE »

Author

Santos, A.F., Riggioni, C., Agache, I., Akdis, C.A., Akdis, M., Alvarez-Perea, A., Alvaro-Lozano, M., Ballmer-Weber, B., Barni, S., Beyer, K., Bindslev-Jensen, C., Brough, H.A., Buyuktiryaki, B., Chu, D., Del Giacco, S., Dunn-Galvin, A., Eberlein, B., Ebisawa, M., Eigenmann, P., Eiwegger, T., Feeney, M., Fernandez-Rivas, M., Fisher, H.R., Fleischer, D.M., Giovannini, M., Gray, C., Hoffmann-Sommergruber, K., Halken, S., O’B Hourihane, J., Jones, C.J., Jutel, M., Knol, E., Konstantinou, G.N., Lack, G., Lau, S., Marques Mejias, A., Marchisotto, M.J., Meyer, R., Mortz, C.G., Moya, B., Muraro, A., Nilsson, C., Camargo Lopes de Oliveira, L., O’Mahony, L., Papadopoulos, N.G., Perrett, K., Peters, R.L., Podesta, M., Poulsen, L.K., Roberts, G., Sampson, H.A., Schwarze, J., Smith, P., Huiwen Tham, E., Untersmayr, E., Van Ree, R., Venter, C., Vickery, B.P., Vlieg-Boerstra, B., Werfel, T., Worm, M., Du Toit, G., and Skypala, I.

Published
2025
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4. A European‐Japanese study on peach allergy: IgE to Pru p 7 associates with severity

Author

Kallen, E. J. J., primary, Revers, A., additional, Fernández‐Rivas, M., additional, Asero, R., additional, Ballmer‐Weber, B., additional, Barreales, L., additional, Belohlavkova, S., additional, de Blay, F., additional, Clausen, M., additional, Dubakiene, R., additional, Ebisawa, M., additional, Fernández‐Perez, C., additional, Fritsche, P., additional, Fukutomi, Y., additional, Gislason, D., additional, Hoffmann‐Sommergruber, K., additional, Jedrzejczak‐Czechowicz, M., additional, Knulst, A. C., additional, Kowalski, M. L., additional, Kralimarkova, T., additional, Lidholm, J., additional, Metzler, C., additional, Mills, E. N. C., additional, Papadopoulos, N. G., additional, Popov, T. A., additional, Purohit, A., additional, Reig, I., additional, Seneviratne, S. L., additional, Sinaniotis, A., additional, Takei, M., additional, Versteeg, S. A., additional, Vassilopoulou, A. E., additional, Vieths, S., additional, Welsing, P. M. J., additional, Zwinderman, A. H., additional, Le, T. M., additional, and Van Ree, R., additional

Published
2023
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5. A European-Japanese study on peach allergy: IgE to Pru p 7 associates with severity

Author

MS Dermatologie/Allergologie, Infection & Immunity, MS Reumatologie/Immunologie/Infectie, Regenerative Medicine and Stem Cells, JC onderzoeksprogramma Methodologie, Lab Reumatologie/Klinische Immunologie, Kallen, E. J.J., Revers, A., Fernández-Rivas, M., Asero, R., Ballmer-Weber, B., Barreales, L., Belohlavkova, S., de Blay, F., Clausen, M., Dubakiene, R., Ebisawa, M., Fernández-Perez, C., Fritsche, P., Fukutomi, Y., Gislason, D., Hoffmann-Sommergruber, K., Jedrzejczak-Czechowicz, M., Knulst, A. C., Kowalski, M. L., Kralimarkova, T., Lidholm, J., Metzler, C., Mills, E. N.C., Papadopoulos, N. G., Popov, T. A., Purohit, A., Reig, I., Seneviratne, S. L., Sinaniotis, A., Takei, M., Versteeg, S. A., Vassilopoulou, A. E., Vieths, S., Welsing, P. M.J., Zwinderman, A. H., Le, T. M., Van Ree, R., MS Dermatologie/Allergologie, Infection & Immunity, MS Reumatologie/Immunologie/Infectie, Regenerative Medicine and Stem Cells, JC onderzoeksprogramma Methodologie, Lab Reumatologie/Klinische Immunologie, Kallen, E. J.J., Revers, A., Fernández-Rivas, M., Asero, R., Ballmer-Weber, B., Barreales, L., Belohlavkova, S., de Blay, F., Clausen, M., Dubakiene, R., Ebisawa, M., Fernández-Perez, C., Fritsche, P., Fukutomi, Y., Gislason, D., Hoffmann-Sommergruber, K., Jedrzejczak-Czechowicz, M., Knulst, A. C., Kowalski, M. L., Kralimarkova, T., Lidholm, J., Metzler, C., Mills, E. N.C., Papadopoulos, N. G., Popov, T. A., Purohit, A., Reig, I., Seneviratne, S. L., Sinaniotis, A., Takei, M., Versteeg, S. A., Vassilopoulou, A. E., Vieths, S., Welsing, P. M.J., Zwinderman, A. H., Le, T. M., and Van Ree, R.

Published
2023

7. Component‐resolved diagnosis and beyond: Multivariable regression models to predict severity of hazelnut allergy

Author

Datema, M. R., van Ree, R., Asero, R., Barreales, L., Belohlavkova, S., de Blay, F., Clausen, M., Dubakiene, R., Fernández‐Perez, C., Fritsche, P., Gislason, D., Hoffmann‐Sommergruber, K., Jedrzejczak‐Czechowicz, M., Jongejan, L., Knulst, A. C., Kowalski, M., Kralimarkova, T. Z., Le, T.‐M., Lidholm, J., Papadopoulos, N. G., Popov, T. A., del Prado, N., Purohit, A., Reig, I., Seneviratne, S. L., Sinaniotis, A., Versteeg, S. A., Vieths, S., Zwinderman, A. H., Mills, E. N. C., Fernández‐Rivas, M., and Ballmer‐Weber, B.

Published
2018
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8. European Surveillance System on Contact Allergies (ESSCA): results with the European baseline series, 2013/14

Author

Uter, W., Amario‐Hita, J.C., Balato, A., Ballmer‐Weber, B., Bauer, A., Belloni Fortina, A., Bircher, A., Chowdhury, M.M.U., Cooper, S.M., Czarnecka‐Operacz, M., Dugonik, A., Gallo, R., Giménez‐Arnau, A., Johansen, J.D., John, S.M., Kieć‐Świerczyńska, M., Kmecl, T., Kręcisz, B., Larese Filon, F., Mahler, V., Pesonen, M., Rustemeyer, T., Sadowska‐Przytocka, A., Sánchez‐Pérez, J., Schliemann, S., Schuttelaar, M.L., Simon, D., Spiewak, R., Valiukevičienė, S., Weisshaar, E., White, I.R., and Wilkinson, S.M.

Published
2017
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9. A new framework for the documentation and interpretation of oral food challenges in population‐based and clinical research

Author

Grabenhenrich, L. B., Reich, A., Bellach, J., Trendelenburg, V., Sprikkelman, A. B., Roberts, G., Grimshaw, K. E. C., Sigurdardottir, S., Kowalski, M. L., Papadopoulos, N. G., Quirce, S., Dubakiene, R., Niggemann, B., Fernández‐Rivas, M., Ballmer‐Weber, B., van Ree, R., Schnadt, S., Mills, E. N. C., Keil, T., and Beyer, K.

Published
2017
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11. The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

Author

Zuberbier, T. Abdul Latiff, A.H. Abuzakouk, M. Aquilina, S. Asero, R. Baker, D. Ballmer-Weber, B. Bangert, C. Ben-Shoshan, M. Bernstein, J.A. Bindslev-Jensen, C. Brockow, K. Brzoza, Z. Chong Neto, H.J. Church, M.K. Criado, P.R. Danilycheva, I.V. Dressler, C. Ensina, L.F. Fonacier, L. Gaskins, M. Gáspár, K. Gelincik, A. Giménez-Arnau, A. Godse, K. Gonçalo, M. Grattan, C. Grosber, M. Hamelmann, E. Hébert, J. Hide, M. Kaplan, A. Kapp, A. Kessel, A. Kocatürk, E. Kulthanan, K. Larenas-Linnemann, D. Lauerma, A. Leslie, T.A. Magerl, M. Makris, M. Meshkova, R.Y. Metz, M. Micallef, D. Mortz, C.G. Nast, A. Oude-Elberink, H. Pawankar, R. Pigatto, P.D. Ratti Sisa, H. Rojo Gutiérrez, M.I. Saini, S.S. Schmid-Grendelmeier, P. Sekerel, B.E. Siebenhaar, F. Siiskonen, H. Soria, A. Staubach-Renz, P. Stingeni, L. Sussman, G. Szegedi, A. Thomsen, S.F. Vadasz, Z. Vestergaard, C. Wedi, B. Zhao, Z. Maurer, M.

Subjects
immune system diseases, parasitic diseases, education, skin and connective tissue diseases
Abstract

This update and revision of the international guideline for urticaria was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GA²LEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), the European Dermatology Forum (EDF; EuroGuiDerm), and the Asia Pacific Association of Allergy, Asthma and Clinical Immunology with the participation of 64 delegates of 50 national and international societies and from 31 countries. The consensus conference was held on 3 December 2020. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS). Urticaria is a frequent, mast cell–driven disease that presents with wheals, angioedema, or both. The lifetime prevalence for acute urticaria is approximately 20%. Chronic spontaneous or inducible urticaria is disabling, impairs quality of life, and affects performance at work and school. This updated version of the international guideline for urticaria covers the definition and classification of urticaria and outlines expert-guided and evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria. © 2021 GA²LEN. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.

Published
2022

14. European Surveillance System on Contact Allergies (ESSCA)

Author

Dittmar, Daan, Uter, Wolfgang, Bauer, Andrea, Fortina, Anna B, Bircher, Andreas J, Czarnecka-Operacz, Magdalena, Dugonik, Aleksandra, Elsner, Peter, Gallo, Rosella, Ghaffar, Sharizan A, Giménez-Arnau, Anna, Johnston, Graham A, Kręcisz, Beata, Filon, Francesca L, Rustemeyer, Thomas, Sadowska-Przytocka, Anna, Sánchez-Pérez, Javier, Schnuch, Axel, Simon, Dagmar, Spiewak, Radoslaw, Spring, Philipp, Corradin, Maria T, Valiukevičienė, Skaidra, Vok, Marko, Weisshaar, Elke, Wilkinson, Mark, Schuttelaar, Marie L, Aberer W, Ballmer-Weber B, Grabbe J, Beiteke U, Brasch J, Fuchs T, John SM, Mahler V, Pesonen M, Jolanki R, Rantanen T, Armario-Hita JC, Fernández-Redondo V, García-Gavín J, Mercader P, Ruiz I, Silvestre JF, Balato A, Ayala F, Peserico A, Sliuziaviciene G, Kieć-Świerczyńska M, Kmecl T, Pandurovic MK, Kecelj N, Lunder T, Simončič Godnič M, Chowdhury MMU, Cooper SM, English JSC, Cousen P, Horne HL, Gawkrodger DJ, Holden C, Sabroe R, Green CM, King CM, Ormerod AD, Samson JE, Statham B, Stone N, White I., Dittmar, Daan, Uter, Wolfgang, Bauer, Andrea, Fortina, Anna B, Bircher, Andreas J, Czarnecka-Operacz, Magdalena, Dugonik, Aleksandra, Elsner, Peter, Gallo, Rosella, Ghaffar, Sharizan A, Giménez-Arnau, Anna, Johnston, Graham A, Kręcisz, Beata, Filon, Francesca L, Rustemeyer, Thoma, Sadowska-Przytocka, Anna, Sánchez-Pérez, Javier, Schnuch, Axel, Simon, Dagmar, Spiewak, Radoslaw, Spring, Philipp, Corradin, Maria T, Valiukevičienė, Skaidra, Vok, Marko, Weisshaar, Elke, Wilkinson, Mark, Schuttelaar, Marie L, Aberer, W, Ballmer-Weber, B, Grabbe, J, Beiteke, U, Brasch, J, Fuchs, T, John, Sm, Mahler, V, Pesonen, M, Jolanki, R, Rantanen, T, Armario-Hita, Jc, Fernández-Redondo, V, García-Gavín, J, Mercader, P, Ruiz, I, Silvestre, Jf, Balato, A, Ayala, F, Peserico, A, Sliuziaviciene, G, Kieć-Świerczyńska, M, Kmecl, T, Pandurovic, Mk, Kecelj, N, Lunder, T, Simončič Godnič, M, Chowdhury, Mmu, Cooper, Sm, English, Jsc, Cousen, P, Horne, Hl, Gawkrodger, Dj, Holden, C, Sabroe, R, Green, Cm, King, Cm, Ormerod, Ad, Samson, Je, Statham, B, Stone, N, White, I., Dermatology, Public Health Research (PHR), Fortina, Ana B., Bircher, Andreas J., Ghaffar, Sharizan A., Johnston, Graham A., Larese Filon, Francesca., Corradin, Maria T., Schuttelaar, Marie L., Aberer, Werner, Ballmer-Weber, Barbara, Grabbe, Jürgen, Beiteke, Ulrike, Brasch, Jochen, Fuchs, Thoma, John, Swen Malte, Mahler, Vera, Pesonen, Maria, Jolanki, Riitta, Rantanen, Tapio, Armario-Hita, José Carlo, Fernández-Redondo, Virginia, García-Gavín, Juan, Mercader, Pedro, Ruiz, Inmaculada, Silvestre, Juan Fco., Balato, Anna, Ayala, Fabio, Peserico, Andrea, Sliuziaviciene, Gondinga, Kieć-Świerczyńska, Marta, Kmecl, Tanja, Pandurovic, Maja Kalac, Kecelj, Nada, Lunder, Tomaž, Simončič Godnič, Mojca, Chowdhury, Mahbub M. U., Cooper, Susan M., English, John S. C., Cousen, Philippa, Horne, Helen L., Gawkrodger, David J., Holden, Catherine, Sabroe, Ruth, Green, Cathy M., King, Codagh M., Ormerod, Anthony D., Samson, Jane E., Statham, Barry, Stone, Natalie, and White, Ian

Subjects
Allergy, Allergic Contact, Occupational Dermatitis, ANGRY BACK SYNDROME, Dermatitis, SUSCEPTIBILITY, medicine.disease_cause, 030207 dermatology & venereal diseases, 0302 clinical medicine, Allergen, Quality of life, QUALITY-OF-LIFE, Adult Allergens Dermatitis, Allergic Contact Dermatitis, Atopic Europe Humans Middle Aged Patch Tests Population Surveillance Prevalence Retrospective Studies Young Adult, Prevalence, Immunology and Allergy, Medicine, Young adult, 610 Medicine & health, DERMATOLOGY IVDK, education.field_of_study, PATCH-TEST REACTIONS, Patch test, BASE-LINE SERIES, clinical epidemiology, Middle Aged, Patch Tests, DERMATITIS-RESEARCH-GROUP, contact allergy, patch test, polysensitization, Adult, Allergens, Dermatitis, Allergic Contact, Dermatitis, Atopic, Europe, Humans, Retrospective Studies, Young Adult, Population Surveillance, Atopic Europe Humans Middle Aged Patch Tests Population Surveillance Prevalence Retrospective Studies Young Adult, GENETIC-FACTORS, Allergic Contact Dermatitis, INFORMATION-NETWORK, Population, Dermatology, Atopic, 2708, 03 medical and health sciences, P-PHENYLENEDIAMINE, education, business.industry, Retrospective cohort study, Adult Allergens Dermatitis, medicine.disease, 030228 respiratory system, business, Demography
Abstract

Background. Polysensitization, defined as being allergic to three or more haptens from the European baseline series, is considered to reflect increased susceptibility to developing a contact allergy, and is likely to be associated with an impaired quality of life.Objectives. To evaluate the prevalences of polysensitization across Europe and to analyse factors associated with polysensitization.Methods. Patch test data collected by the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc.org) in consecutively patch tested patients from January 2009 to December 2014, comprising 11 countries and 57 departments, were retrospectively analysed.Results. A total of 86 416 patients were available for analysis, showing a standardized prevalence of polysensitization of 7.02%, ranging from 12.7% (Austria) to 4.6% (Italy). Allergen pairs with the strongest association are reported for the total population, for South Europe, and for North/Central Europe. Overall, polysensitized patients showed a higher percentage of extreme (+++) positive patch test reactions than oligosensitized patients. Female sex, occupational dermatitis and age > 40 years were risk factors for polysensitization.Conclusions. The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Knownrisk factors for polysensitization are confirmed in a European dermatitis population.

Published
2018
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16. The EuroPrevall outpatient clinic study on food allergy: background and methodology

Author

Fernández-Rivas, M., Barreales, L., Mackie, A. R., Fritsche, P., Vázquez-Cortés, S., Jedrzejczak-Czechowicz, M., Kowalski, M. L., Clausen, M., Gislason, D., Sinaniotis, A., Kompoti, E., Le, T.-M., Knulst, A. C., Purohit, A., de Blay, F., Kralimarkova, T., Popov, T., Asero, R., Belohlavkova, S., Seneviratne, S. L., Dubakiene, R., Lidholm, J., Hoffmann-Sommergruber, K., Burney, P., Crevel, R., Brill, M., Fernández-Pérez, C., Vieths, S., Mills, Clare E. N., van Ree, R., and Ballmer-Weber, B. K.

Published
2015
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17. IgE recognition patterns in peanut allergy are age dependent: perspectives of the EuroPrevall study

Author

Ballmer-Weber, B. K., Lidholm, J., Fernández-Rivas, M., Seneviratne, S., Hanschmann, K.-M., Vogel, L., Bures, P., Fritsche, P., Summers, C., Knulst, A. C., Le, T.-M., Reig, I., Papadopoulos, N. G., Sinaniotis, A., Belohlavkova, S., Popov, T., Kralimarkova, T., de Blay, F., Purohit, A., Clausen, M., Jedrzejczak-Czechowcz, M., Kowalski, M. L., Asero, R., Dubakiene, R., Barreales, L., Clare Mills, E. N., van Ree, R., and Vieths, S.

Published
2015
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19. EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy

Author

Muraro, A., Werfel, T., Hoffmann-Sommergruber, K., Roberts, G., Beyer, K., Bindslev-Jensen, C., Cardona, V., Dubois, A., duToit, G., Eigenmann, P., Rivas, Fernandez M., Halken, S., Hickstein, L., Hst, A., Knol, E., Lack, G., Marchisotto, M. J., Niggemann, B., Nwaru, B. I., Papadopoulos, N. G., Poulsen, L. K., Santos, A. F., Skypala, I., Schoepfer, A., Van Ree, R., Venter, C., Worm, M., Vlieg–Boerstra, B., Panesar, S., de Silva, D., Soares-Weiser, K., Sheikh, A., Ballmer-Weber, B. K., Nilsson, C., de Jong, N. W., and Akdis, C. A.

Published
2014
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20. The prevalence and distribution of food sensitization in European adults

Author

Burney, P. G. J., Potts, J., Kummeling, I., Mills, E. N. C., Clausen, M., Dubakiene, R., Barreales, L., Fernandez-Perez, C., Fernandez-Rivas, M., Le, T.-M., Knulst, A. C., Kowalski, M. L., Lidholm, J., Ballmer-Weber, B. K., Braun-Fahlander, C., Mustakov, T., Kralimarkova, T., Popov, T., Sakellariou, A., Papadopoulos, N. G., Versteeg, S. A., Zuidmeer, L., Akkerdaas, J. H., Hoffmann-Sommergruber, K., and van Ree, R.

Published
2014
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21. Proposal of 0.5 mg of protein/100 g of processed food as threshold for voluntary declaration of food allergen traces in processed food—A first step in an initiative to better inform patients and avoid fatal allergic reactions: A GA²LEN position paper

Author

Zuberbier, T. Dörr, T. Aberer, W. Alvaro, M. Angier, E. Arasi, S. Arshad, H. Ballmer-Weber, B. Bartra, J. Beck, L. Bégin, P. Bindslev-Jensen, C. Bislimovska, J. Bousquet, J. Brockow, K. Bush, A. Cianferoni, A. Cork, M.J. Custovic, A. Darsow, U. de Jong, N. Deleanu, D. Del Giacco, S. Deschildre, A. Dunn Galvin, A. Ebisawa, M. Fernández-Rivas, M. Ferrer, M. Fiocchi, A. Gerth van Wijk, R. Gotua, M. Grimshaw, K. Grünhagen, J. Heffler, E. Hide, M. Hoffmann-Sommergruber, K. Incorvaia, C. Janson, C. Malte John, S. Jones, C. Jutel, M. Katoh, N. Kendziora, B. Kinaciyan, T. Knol, E. Kurbacheva, O. Lau, S. Loh, R. Lombardi, C. Mäkelä, M. Marchisotto, M.J. Makris, M. Maurer, M. Meyer, R. Mijakoski, D. Minov, J. Mullol, J. Nilsson, C. Nowak–Wegrzyn, A. Nwaru, B.I. Odemyr, M. Pajno, G.B. Paudel, S. Papadopoulos, N.G. Renz, H. Ricci, G. Ring, J. Rogala, B. Sampson, H. Senna, G. Sitkauskiene, B. Smith, P.K. Stevanovic, K. Stoleski, S. Szajewska, H. Tanaka, A. Todo-Bom, A. Topal, F.A. Valovirta, E. Van Ree, R. Venter, C. Wöhrl, S. Wong, G.W.K. Zhao, Z. Worm, M.

Subjects
digestive, oral, and skin physiology
Abstract

Background: Food anaphylaxis is commonly elicited by unintentional ingestion of foods containing the allergen above the tolerance threshold level of the individual. While labeling the 14 main allergens used as ingredients in food products is mandatory in the EU, there is no legal definition of declaring potential contaminants. Precautionary allergen labeling such as “may contain traces of” is often used. However, this is unsatisfactory for consumers as they get no information if the contamination is below their personal threshold. In discussions with the food industry and technologists, it was suggested to use a voluntary declaration indicating that all declared contaminants are below a threshold of 0.5 mg protein per 100 g of food. This concentration is known to be below the threshold of most patients, and it can be technically guaranteed in most food production. However, it was also important to assess that in case of accidental ingestion of contaminants below this threshold by highly allergic patients, no fatal anaphylactic reaction could occur. Therefore, we performed a systematic review to assess whether a fatal reaction to 5mg of protein or less has been reported, assuming that a maximum portion size of 1kg of a processed food exceeds any meal and thus gives a sufficient safety margin. Methods: MEDLINE and EMBASE were searched until 24 January 2021 for provocation studies and case reports in which one of the 14 major food allergens was reported to elicit fatal or life-threatening anaphylactic reactions and assessed if these occurred below the ingestion of 5mg of protein. A Delphi process was performed to obtain an expert consensus on the results. Results: In the 210 studies included, in our search, no reports of fatal anaphylactic reactions reported below 5 mg protein ingested were identified. However, in provocation studies and case reports, severe reactions below 5 mg were reported for the following allergens: eggs, fish, lupin, milk, nuts, peanuts, soy, and sesame seeds. Conclusion: Based on the literature studied for this review, it can be stated that cross-contamination of the 14 major food allergens below 0.5 mg/100 g is likely not to endanger most food allergic patients when a standard portion of food is consumed. We propose to use the statement “this product contains the named allergens in the list of ingredients, it may contain traces of other contaminations (to be named, e.g. nut) at concentrations less than 0.5 mg per 100 g of this product” for a voluntary declaration on processed food packages. This level of avoidance of cross-contaminations can be achieved technically for most processed foods, and the statement would be a clear and helpful message to the consumers. However, it is clearly acknowledged that a voluntary declaration is only a first step to a legally binding solution. For this, further research on threshold levels is encouraged. © 2021 The Authors. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.

Published
2021

22. Update Leitlinie zum Management IgE-vermittelter Nahrungsmittelallergien – S2k-Leitline der DGAKI

Author

Worm, M., primary, Reese, I., additional, Ballmer-Weber, B., additional, Beyer, K., additional, Bischoff, S.C., additional, Bohle, B., additional, Brockow, K., additional, Claßen, M., additional, Fischer, P.J., additional, Hamelmann, E., additional, Jappe, U., additional, Tebbe, J. Kleine-, additional, Klimek, L., additional, Koletzko, B., additional, Lange, L., additional, Lau, S., additional, Lepp, U., additional, Mahler, V., additional, Nemat, K., additional, Raithel, M., additional, Saloga, J., additional, Schäfer, C., additional, Schnadt, S., additional, Schreiber, J., additional, Szépfalusi, Z., additional, Treudler, R., additional, Wagenmann, M., additional, Werfel, T., additional, and Zuberbier, T., additional

Published
2021
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26. Is benzyl alcohol a significant contact sensitizer?

Author

Geier, J., Ballmer‐Weber, B., Buhl, T., Rieker‐Schwienbacher, J., Mahler, V., Dickel, H., Schubert, S., Baron, Jens Malte, Grabbe, Jürgen, Siedlecki, Katharina, Strom, Kerstin, Hartmann, Karin, Worm, Margitta, Simon, Dagmar, Effendy, Isaak, Dickel, Heinrich, Fartasch, Manigé, Vieluf, Dieter, Beiteke, Ulrike, and Bauer, Andrea

Subjects
*BENZYL alcohol, *ALLERGENS, *INFORMATION networks, *RELIABILITY in engineering, *TEST reliability
Abstract

Background: Benzyl alcohol is a widely used preservative, solvent and fragrance material. According to published data, it is a rare sensitizer in humans. Objectives: To identify characteristics and sensitization patterns of patients with positive patch test reactions to benzyl alcohol and to check the reliability of the patch test preparation benzyl alcohol 1% pet. Patients and Methods: Retrospective analysis of data from the Information Network of Departments of Dermatology (IVDK), 2010–2019. Results: Of 70 867 patients patch tested with benzyl alcohol 1% pet., 146 (0.21%) showed a positive reaction, most of them (89%) only weakly positive. The number of doubtful and irritant reactions significantly exceeded the number of positive reactions. Reproducibility of positive test reactions was low. Among benzyl alcohol‐positive patients, compared to benzyl alcohol‐negative patients, there were significantly more patients with leg dermatitis (17.8% vs. 8.6%), more patients aged 40 years or more (81.5% vs. 70.5%) and more patients who were tested because of a suspected intolerance reaction to topical medications (34.9% vs. 16.6%). Concomitant positive reactions were mainly seen to fragrances, preservatives and ointment bases. Conclusions: Sensitization to benzyl alcohol occurs very rarely, mainly in patients with stasis dermatitis. In view of our results, benzyl alcohol cannot be regarded as a significant contact allergen, and therefore marking it as skin sensitizer 1B and labelling it with H 317 is not helpful. [ABSTRACT FROM AUTHOR]

Published
2022
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29. The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

Author

Zuberbier, T., primary, Aberer, Werner, primary, Asero, R., primary, Abdul Latiff, A. H., primary, Baker, D., primary, Ballmer-Weber, B., primary, Bernstein, J. A., primary, Bindslev-Jensen, C., primary, Brzoza, Z., primary, Buense Bedrikow, R., primary, Canonica, G. W., primary, Church, M. K., primary, Craig, T., primary, Danilycheva, I. V., primary, Dressler, C., primary, Ensina, L. F., primary, Gimenez-Arnau, A., primary, Godse, K., primary, Goncalo, M., primary, Grattan, C., primary, and Hebert, J., primary

Published
2021
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35. EAACI/GA(2)LEN/EDF/WAO guidelines for the definition, classification, diagnosis and treatment of urticaria

Author

Zuberbier, T., Aberer, W., Asero, R., Latiff, A. H. Abdul, Baker, D., Ballmer-Weber, B., Bernstein, J. A., Bindslev-Jensen, C., Brzoza, Z., Bedrikow, R. Buense, Canonica, G. W., Church, M. K., Craig, T., Danilycheva V, I., Dressler, C., Ensina, L. F., Gimenez-Arnau, A., Godse, K., Goncalo, M., Grattan, C., Hebert, J., Hide, M., Kaplan, A., Kapp, A., Katelaris, C. H., Kocaturk, E., Kulthanan, K., Larenas-Linnemann, D., Leslie, T. A., Magerl, M., Mathelier-Fusade, P., Meshkova, R. Y., Metz, M., Nast, A., Nettis, E., Oude-Elberink, H., Rosumeck, S., Saini, S. S., Sanchez-Borges, M., Schmid-Grendelmeier, P., Staubach, P., Sussman, G., Toubi, E., Vena, G. A., Vestergaard, C., Wedi, B., Werner, R. N., Zhao, Z., and Maurer, M.

Published
2020
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