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45 results on '"Balligand, Marc"'

1. Determination of Canine Long Bone Ultimate Tensile Strain by Digital Image Correlation

Author

Böhme, Beatrice, Laurent, Cédric, Milis, Olivier, Ponthot, Jean-Phillippe, and Balligand, Marc

Subjects
Physics - Medical Physics, Physics - Classical Physics
Abstract

Creating finite element models for simulation of bone behaviour, fracture occurrence and propagation requires feeding the system with adequate mechanical data. To date, little is known about the mechanical behaviour of long canine bones, and in cases of modelling a bone-breakage scenario the ultimate strain at failure still needs to be determined. Extrapolation from human literature or other species is uninteresting as differences of mechanical properties between species are expected (Vahey et al, 1987) [1]. Our purpose was to measure the ultimate tensile strain of canine long bones by Digital Image Correlation (DIC), an optical technique to measure strain under load and a promising measurement method for our purpose. Tension tests of cortical bone strips and flexion tests of entire bones were performed, and the ultimate tensile strain was measured and compared between different specimen and testing scenarios., Comment: Journal of Orthopedic Research and Therapy, Gavin Publishers, 2022

Published
2022
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6. Session 1: Orthopaedics

Author

Soares, Diana, primary, Allen, Matthew J, additional, Burton, Neil J, additional, Mella, Stephanie, additional, Meeson, Richard, additional, Dirrig, Helen, additional, Murugarren, Maider, additional, Piana, Francesco, additional, Solano, Miguel, additional, Phipps, William, additional, Richard, Megan, additional, Rincon, Javier, additional, Aisa, Josep, additional, Tomlinson, Andrew, additional, Vicente, Felipe de, additional, Picavet, Pierre, additional, Balligand, Marc, additional, Claeys, Stéphanie, additional, Potamopoulou, Maria, additional, Brown, Gordon, additional, Whitelock, Richard, additional, García, Alba Rial, additional, and Ridge, Patrick, additional

Published
2021
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19. Short-Term Bone Healing Response to Mechanical Stimulation - A Case Series Conducted on Sheep

Author

Barcik, Jan, Ernst, Manuela, Balligand, Marc, Dlaska, Constantin, Drenchev, Ludmil, Zeiter, Stephan, Epari, Devakar, Windolf, Markus, Barcik, Jan, Ernst, Manuela, Balligand, Marc, Dlaska, Constantin, Drenchev, Ludmil, Zeiter, Stephan, Epari, Devakar, and Windolf, Markus

Abstract

It is well known that mechanical stimulation promotes indirect fracture healing by triggering callus formation. We investigated the short-term response of healing tissue to mechanical stimulation to compare the changes in tissue stiffness during stimulation and resting phases in a preclinical case-series. Four sheep underwent a tibial osteotomy and were instrumented with a custom-made active fixator which applied a mechanical stimulation protocol of 1000 cycles/day, equally distributed over 12 h, followed by 12 h of rest. During each cycle, a surrogate metric for tissue stiffness was measured, enabling a continuous real-time monitoring of the healing progression. A daily stiffness increase during stimulation and an increase during resting were evaluated for each animal. One animal had to be excluded from the evaluation due to technical reasons. For all included animals, the stiffness began to increase within the second week post-op. A characteristic pattern was observed during daily measurements: the stiffness dropped considerably within the first stimulation cycles followed by a steady rise throughout the rest of the stimulation phase. However, for all included animals, the average daily stiffness increase within the first three weeks post operation was larger during resting than during stimulation (Sheep I: 16.9% vs. −5.7%; Sheep II: 14.7% vs. −1.8%; Sheep III: 8.9% vs. 1.6%). A continuous measurement of tissue stiffness together with a controlled fracture stimulation enabled the investigation of the short-term effects of specific stimulatory parameters, such as resting periods. Resting was identified as a potentially determining factor for bone healing progression. Optimizing the ratio between stimulation and resting may contribute to more robust fracture healing in the future

Published
2021

22. Effect of orthopedic implants on canine long bone compression stiffness: a combined experimental and computational approach.

Author

de Brosses, Emilie, Ganghoffer, Jean-François, Laurent, Cédric P, Böhme, Béatrice, Verwaerde, Jolanthe, Papeleux, Luc, Ponthot, Jean-Philippe, and Balligand, Marc

Abstract

Osteosynthesis for canine long bones is a complex process requiring knowledge of biology, surgical techniques and (bio)mechanical principles. Subject-specific finite element analysis constitutes a promising tool to evaluate the effect of surgical intervention on the global properties of a bone-implant construct, but suffers from a lack of validation. In this study, the biomechanical behavior of 10 canine humeri was compared before and after creation of a 10 mm bone defect stabilized with an eight-hole locking compression plate (Synthes®) and two locking screws on each fragment. The response under compression of both intact and plated samples was measured experimentally and reproduced with a finite element model. The experimental stiffness ratio between plated and intact bone was equal to 0.39 ± 0.06. A subject-specific finite element analysis including density-dependent elasto-plastic material properties for canine bone and automatic generation of orthopedic implants was then conducted to recover these experimental results. The stiffness of intact and plated samples could be predicted, with no significant differences with experimental data. The simulated stiffness ratio between plated and intact canine bone was equal to 0.43 ± 0.03. This study constitutes a first step toward the building of a virtual database of pre-computed cases, aiming at helping the veterinary surgeons to make decisions regarding the most suited orthopedic solution for a given dog and a given fracture. [ABSTRACT FROM AUTHOR]

Published
2020
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23. A randomized, double-blind, prospective, placebo-controlled study of the efficacy of a diet supplemented with curcuminoids extract, hydrolyzed collagen and green tea extract in owner’s dogs with osteoarthritis

Author

Comblain, Fanny, primary, Barthélémy, Nicolas, additional, Lefèbvre, Michael, additional, Schwartz, Cédric, additional, Lesponne, Isabelle, additional, Serisier, Samuel, additional, Feugier, Alexandre, additional, Balligand, Marc, additional, and Henrotin, Yves, additional

Published
2017
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34. Study of spinal cord evoked injury potential by use of computer modeling and in dogs with naturally acquired thoracolumbar spinal cord compression

Author

Poncelet, Luc, Balligand, Marc, Michaux, Charles, Poncelet, Luc, Balligand, Marc, and Michaux, Charles

Abstract

Objective - To add objective measurements of the characteristics of evoked injury potentials (EIP) and their relations to clinical severity in dogs with thoracolumbar spinal cord damage. Animals - 25 dogs with naturally acquired spinal cord compression attributable to disk extrusion or vertebral fracture at the level of the thoracolumbar junction and with various degrees of paresis/paralysis. Procedure - Spinal cord potentials evoked by tibial nerve stimulation were recorded every 5 to 10 mm at the lamina level in the vicinity of the cord compression. This allowed an EIP to be recorded even in the least handicapped dogs. A computer model yielded information about the waveform changes of the EIP in the vicinity of conduction blocks. Results - The EIP waveform changed from biphasic to monophasic a short distance caudad to the location of spinal cord compression. Location of a maximal conduction block was measured in relation to position of the electrodes recording this waveform change. The distance between the assumed conduction block and the actual spinal cord compression was larger in the most affected dogs. The amplitude of the EIP was not related to severity of the clinical picture; however, the proximity of the recording electrode to the spine influenced the amplitude and the waveform of the EIP. Conclusion and Clinical Relevance - Change in the EIP waveform from biphasic to monophasic makes it possible to estimate the conduction block location along the spinal cord. A large distance between the assumed conduction block and site of actual cord compression could be an objective argument to confirm severity of a lesion., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1998

43. Bilateral contracture of the carpal and digital flexor muscles resulting in carpal flexural deformity in a cat.

Author

Vrijsen E, Hamon M, Picavet P, Bouvy B, and Balligand M

Abstract

Case Summary: A 12-year-old neutered female domestic shorthair cat was presented with bilateral progressive forelimb lameness that was unresponsive to anti-inflammatory drugs. Bilateral carpal flexural deformity with hyperflexion of multiple toes of the right forelimb was observed. In the absence of abnormalities detected on radiographs and ultrasound, a bilateral contracture of the carpal and digital flexor muscles was diagnosed. Treatment consisted of single-session bilateral selective tenectomies (5 mm) of the flexor carpi ulnaris, flexor carpi radialis and superficial digital flexor muscle tendons on the left forelimb and tendons of the flexor carpi ulnaris muscle, and branches of the third and fourth digit of the deep digital flexor muscle on the right forelimb. Two months postoperatively, selective tenectomies (10 mm) were performed due to contracture recurrence on the left forelimb. The subjective outcome was rated as good 6 months postoperatively., Relevance and Novel Information: Digital and/or carpal contractures are rarely described in (feline) veterinary medicine and are limited to a few case reports. The exact aetiology remains unknown. A traumatic/iatrogenic origin seems to be the most likely cause. Surgery is indicated, consisting of selective tenectomy and/or tenotomy, and is associated with minor complications and an excellent outcome. This case report describes the presence, treatment and successful outcome of a cat with bilateral carpal and digital flexor muscle contractures resulting in carpal flexural deformity with valgus deviation treated with selective tenectomies., Competing Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2023.)

Published
2023
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44. Patellar Proximo-Distal Displacement following Modified Maquet Technique Is Not Predictive of Patellar Luxation.

Author

Giansetto TE, Pierrot E, Picavet PP, Lefebvre M, Rives A, Farnir F, Claeys S, and Balligand M

Subjects
Dogs, Animals, Patella surgery, Stifle surgery, Patellar Dislocation veterinary, Dog Diseases surgery
Abstract

Objective: The aim of this study was to test the low sensitivity of the Allberg and Miles index to the stifle opening angle, evaluate the displacement of the patella after a Modified Maquet Technique using this index and assess the incidence of patellar luxation post-Modified Maquet Technique in dogs., Study Design:  Medical records were reviewed from 2012 to 2017. Allberg Miles index were determined for each stifle pre- and postoperatively, as well as the stifle joint opening of each case. Occurrence of patellar luxation was recorded., Results:  137 stifles on 116 dogs were reviewed. The stifle opening angle did not influence the Allberg Miles index. Pre- and postoperative index showed a distal displacement of the patella after a Modified Maquet Procedure, especially at 135° of stifle opening angle. Only 1/137 cases demonstrated patellar luxation after the surgery., Conclusion:  Based on our statistical analysis, we were able to conclude that within the maximum stifle opening angle range recorded in our series of cases; the Allberg Miles index variation was not significant. While patellar baja is clearly induced by the Modified Maquet Technique, the latter did not seem to predispose patients to post-operative patellar luxation in our study population., Competing Interests: None declared., (Thieme. All rights reserved.)

Published
2023
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45. Effect of orthopedic implants on canine long bone compression stiffness: a combined experimental and computational approach.

Author

Laurent CP, Böhme B, Verwaerde J, Papeleux L, Ponthot JP, and Balligand M

Subjects
Animals, Biomechanical Phenomena, Dogs, Finite Element Analysis, Compressive Strength, Humerus physiology, Mechanical Tests, Orthopedics, Prostheses and Implants
Abstract

Osteosynthesis for canine long bones is a complex process requiring knowledge of biology, surgical techniques and (bio)mechanical principles. Subject-specific finite element analysis constitutes a promising tool to evaluate the effect of surgical intervention on the global properties of a bone-implant construct, but suffers from a lack of validation. In this study, the biomechanical behavior of 10 canine humeri was compared before and after creation of a 10 mm bone defect stabilized with an eight-hole locking compression plate (Synthes ® ) and two locking screws on each fragment. The response under compression of both intact and plated samples was measured experimentally and reproduced with a finite element model. The experimental stiffness ratio between plated and intact bone was equal to 0.39 ± 0.06. A subject-specific finite element analysis including density-dependent elasto-plastic material properties for canine bone and automatic generation of orthopedic implants was then conducted to recover these experimental results. The stiffness of intact and plated samples could be predicted, with no significant differences with experimental data. The simulated stiffness ratio between plated and intact canine bone was equal to 0.43 ± 0.03. This study constitutes a first step toward the building of a virtual database of pre-computed cases, aiming at helping the veterinary surgeons to make decisions regarding the most suited orthopedic solution for a given dog and a given fracture.

Published
2020
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