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2. May Measure Month 2022 in Italy: A Focus on Fixed-dose Combination, Therapeutic Adherence, and Medical Inertia in a Nationwide Survey

Author

Del Pinto, R, Agabiti Rosei, C, Borghi, C, Cipollini, F, Cottone, S, De Giorgi, G, Di Guardo, A, Dugnani, M, Fabris, B, Giannattasio, C, Giacchetti, G, Minuz, P, Mulè, G, Nazzaro, P, Parati, G, Rattazzi, M, Saladini, F, Salvetti, M, Sarzani, R, Savoia, C, Tocci, G, Veglio, F, Volpe, M, Vulpis, V, Baldini, G, Ferri, C, Muiesan, M, Del Pinto R., Agabiti Rosei C., Borghi C., Cipollini F., Cottone S., De Giorgi G. A., Di Guardo A., Dugnani M., Fabris B., Giannattasio C., Giacchetti G., Minuz P., Mulè G., Nazzaro P., Parati G., Rattazzi M., Saladini F., Salvetti M., Sarzani R., Savoia C., Tocci G., Veglio F., Volpe M., Vulpis V., Baldini G., Ferri C., Muiesan M. L., Del Pinto, R, Agabiti Rosei, C, Borghi, C, Cipollini, F, Cottone, S, De Giorgi, G, Di Guardo, A, Dugnani, M, Fabris, B, Giannattasio, C, Giacchetti, G, Minuz, P, Mulè, G, Nazzaro, P, Parati, G, Rattazzi, M, Saladini, F, Salvetti, M, Sarzani, R, Savoia, C, Tocci, G, Veglio, F, Volpe, M, Vulpis, V, Baldini, G, Ferri, C, Muiesan, M, Del Pinto R., Agabiti Rosei C., Borghi C., Cipollini F., Cottone S., De Giorgi G. A., Di Guardo A., Dugnani M., Fabris B., Giannattasio C., Giacchetti G., Minuz P., Mulè G., Nazzaro P., Parati G., Rattazzi M., Saladini F., Salvetti M., Sarzani R., Savoia C., Tocci G., Veglio F., Volpe M., Vulpis V., Baldini G., Ferri C., and Muiesan M. L.

Abstract

Introduction: Hypertension is the main risk factor for cardiovascular diseases (CVD). Notably, only about half of hypertensive patients manage to achieve the recommended blood pressure (BP) control. Main reasons for the persistence of uncontrolled BP during treatment are lack of compliance on the patients' side, and therapeutic inertia on physicians' side. Methods: During the global BP screening campaign "May Measure Month" (MMM) (May 1st to July 31st, 2022), a nationwide, cross-sectional, opportunistic study endorsed by the Italian Society of Hypertension was conducted on volunteer adults ≥ 18 years to raise awareness of the health issues surrounding high BP. A questionnaire on demographic/clinical features and questions on the use of fixed-dose single-pills for the treatment of hypertension was administered. BP was measured with standard procedures. Results: A total of 1612 participants (mean age 60.0±15.41 years; 44.7% women) were enrolled. Their mean BP was 128.5±18.1/77.1±10.4 mmHg. About half of participants were sedentary, or overweight/obese, or hypertensive. 55.5% individuals with complete BP assessment had uncontrolled hypertension. Most were not on a fixed-dose combination of antihypertensive drugs and did not regularly measure BP at home. Self-reported adherence to BP medications was similar between individuals with controlled and uncontrolled BP (95% vs 95.5%). Conclusions: This survey identified a remarkable degree of therapeutic inertia and poor patients' involvement in the therapeutic process and its monitoring in the examined population, underlining the importance of prevention campaigns to identify areas of unsatisfactory management of hypertension, to increase risk factors' awareness in the population with the final purpose of reducing cardiovascular risk.

Published
2024

3. Mechanical bowel preparation in elective colorectal surgery: a propensity score-matched analysis of the Italian colorectal anastomotic leakage (iCral) study group prospective cohorts

Author

Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Patriti, A, Campagnacci, R, Sica, G, Caricato, M, Montemurro, L, Ciano, P, Benedetti, M, Guercioni, G, Scatizzi, M, De Luca, R, Ficari, F, Scabini, S, Liverani, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Cicconi, S, Marziali, I, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Sisti, V, Ricci, M, Maurizi, A, Sensi, B, Capolupo, G, Pandolfini, L, Falsetto, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Aprile, A, Soriero, D, Scarinci, A, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Pirozzi F., Delrio P., Garulli G., Marini P., Patriti A., Campagnacci R., Sica G., Caricato M., Montemurro L. A., Ciano P., Benedetti M., Guercioni G., Scatizzi M., De Luca R., Ficari F., Scabini S., Liverani A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Mattei M. S., Belloni E., Apa D., Di Carlo M., Cicconi S., Marziali I., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Sisti V., Ricci M. L., Maurizi A., Sensi B., Capolupo G. T., Pandolfini L., Falsetto A., Simone M., Giudici F., Cianchi F., Baldini G., Aprile A., Soriero D., Scarinci A., Sagnotta A., Molfino S., Amodio P., Cardinali A., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., La Gioia G., Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Patriti, A, Campagnacci, R, Sica, G, Caricato, M, Montemurro, L, Ciano, P, Benedetti, M, Guercioni, G, Scatizzi, M, De Luca, R, Ficari, F, Scabini, S, Liverani, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Cicconi, S, Marziali, I, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Sisti, V, Ricci, M, Maurizi, A, Sensi, B, Capolupo, G, Pandolfini, L, Falsetto, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Aprile, A, Soriero, D, Scarinci, A, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Pirozzi F., Delrio P., Garulli G., Marini P., Patriti A., Campagnacci R., Sica G., Caricato M., Montemurro L. A., Ciano P., Benedetti M., Guercioni G., Scatizzi M., De Luca R., Ficari F., Scabini S., Liverani A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Mattei M. S., Belloni E., Apa D., Di Carlo M., Cicconi S., Marziali I., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Sisti V., Ricci M. L., Maurizi A., Sensi B., Capolupo G. T., Pandolfini L., Falsetto A., Simone M., Giudici F., Cianchi F., Baldini G., Aprile A., Soriero D., Scarinci A., Sagnotta A., Molfino S., Amodio P., Cardinali A., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., and La Gioia G.

Abstract

Retrospective evaluation of the effects of mechanical bowel preparation (MBP) on data derived from two prospective open-label observational multicenter studies in Italy regarding elective colorectal surgery. MBP for elective colorectal surgery remains a controversial issue with contrasting recommendations in current guidelines. The Italian ColoRectal Anastomotic Leakage (iCral) study group, therefore, decided to estimate the effects of no MBP (treatment variable) versus MBP for elective colorectal surgery. A total of 8359 patients who underwent colorectal resection with anastomosis were enrolled in two consecutive prospective studies in 78 surgical centers in Italy from January 2019 to September 2021. A retrospective PSMA was performed on 5455 (65.3%) cases after the application of explicit exclusion criteria to eliminate confounders. The primary endpoints were anastomotic leakage (AL) and surgical site infections (SSI) rates; the secondary endpoints included SSI subgroups, overall and major morbidity, reoperation, and mortality rates. Overall length of postoperative hospital stay (LOS) was also considered. Two well-balanced groups of 1125 patients each were generated: group A (No MBP, true population of interest), and group B (MBP, control population), performing a PSMA considering 21 covariates. Group A vs. group B resulted significantly associated with a lower risk of AL [42 (3.5%) vs. 73 (6.0%) events; OR 0.57; 95% CI 0.38–0.84; p = 0.005]. No difference was recorded between the two groups for SSI [73 (6.0%) vs. 85 (7.0%) events; OR 0.88; 95% CI 0.63–1.22; p = 0.441]. Regarding the secondary endpoints, no MBP resulted significantly associated with a lower risk of reoperation and LOS > 6 days. This study confirms that no MBP before elective colorectal surgery is significantly associated with a lower risk of AL, reoperation rate, and LOS < 6 days when compared with MBP.

Published
2024

6. Revealing faint compact radio jets at redshifts above 5 with very long baseline interferometry.

Author

Krezinger, M., Baldini, G., Giroletti, M., Sbarrato, T., Ghisellini, G., Giovannini, G., An, T., Gabányi, K. É., and Frey, S.

Subjects
*VERY long baseline interferometry, *SUPERMASSIVE black holes, *RADIO galaxies, *GALACTIC redshift, *BRIGHTNESS temperature, *QUASARS
Abstract

Context. Over the past two decades, our knowledge of the high-redshift (z > 5) radio quasars has expanded, thanks to dedicated high-resolution very long baseline interferometry (VLBI) observations. Distant quasars provide unique information about the formation and evolution of the first galaxies and supermassive black holes in the Universe. Powerful relativistic jets are likely to have played an essential role in these processes. However, the sample of VLBI-observed radio quasars is still too small to allow meaningful statistical conclusions. Aims. We extend the list of the VLBI observed radio quasars to investigate how the source structure and physical parameters are related to radio loudness. Methods. We assembled a sample of ten faint radio quasars located at 5 < z < 6 with their radio-loudness indices spanning between 0.9 − 76. We observed the selected targets with the European VLBI Network (EVN) at 1.7 GHz. The milliarcsecond-scale resolution of VLBI at this frequency allowed us to probe the compact innermost parts of radio-emitting relativistic jets. In addition to the single-band VLBI observations, we collected single-dish and low-resolution radio interferometric data to investigate the spectral properties and variability of our sources. Results. The detection rate of this high-redshift, low-flux-density sample is 90%, with only one target (J0306+1853) remaining undetected. The other nine sources appear core-dominated and show a single, faint and compact radio core on this angular scale. The derived radio powers are typical of Fanaroff-Riley II radio galaxies and quasars. By extending our sample with other VLBI-detected z > 5 sources from the literature, we found that the core brightness temperatures and monochromatic radio powers tend to increase with radio loudness. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Patient-generated subjective global assessment (PG-SGA) better identifies malnourished patients and better correlates with functional capacity than global leadership initiative on malnutrition (GLIM) criteria

Author

Fiorindi, C., primary, Baldini, G., additional, Testa, G.D., additional, Foti, L., additional, Alpigiano, G., additional, Bertulli, L., additional, Campani, F., additional, Cherici, S., additional, Sartini, L., additional, Tognozzi, C., additional, Romagnoli, S., additional, Cianchi, F., additional, Mechi, M.T., additional, and Nannoni, A., additional

Published
2023
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9. Three-row versus two-row circular staplers for left-sided colorectal anastomosis: a propensity score-matched analysis of the iCral 2 and 3 prospective cohorts

Author

Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Scatizzi, M, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Campagnacci, R, De Luca, R, Ficari, F, Sica, G, Scabini, S, Liverani, A, Caricato, M, Patriti, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Guercioni, G, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Ciano, P, Benedetti, M, Montemurro, L, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Pandolfini, L, Falsetto, A, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Maurizi, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Sensi, B, Aprile, A, Soriero, D, Scarinci, A, Capolupo, G, Sisti, V, Ricci, M, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Cicconi, S, Marziali, I, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Scatizzi M., Pirozzi F., Delrio P., Garulli G., Marini P., Campagnacci R., De Luca R., Ficari F., Sica G., Scabini S., Liverani A., Caricato M., Patriti A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Guercioni G., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Ciano P., Benedetti M., Montemurro L. A., Mattei M. S., Belloni E., Apa D., Di Carlo M., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Pandolfini L., Falsetto A., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Maurizi A., Simone M., Giudici F., Cianchi F., Baldini G., Sensi B., Aprile A., Soriero D., Scarinci A., Capolupo G. T., Sisti V., Ricci M. L., Sagnotta A., Molfino S., Amodio P., Cardinali A., Cicconi S., Marziali I., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., La Gioia G., Catarci, M, Guadagni, S, Masedu, F, Ruffo, G, Viola, M, Borghi, F, Baldazzi, G, Scatizzi, M, Pirozzi, F, Delrio, P, Garulli, G, Marini, P, Campagnacci, R, De Luca, R, Ficari, F, Sica, G, Scabini, S, Liverani, A, Caricato, M, Patriti, A, Mancini, S, Baiocchi, G, Santoro, R, Siquini, W, Guercioni, G, Basti, M, Pedrazzani, C, Totis, M, Carrara, A, Lucchi, A, Pavanello, M, Muratore, A, D'Ugo, S, Di Leo, A, Pignata, G, Elmore, U, Anania, G, Carlini, M, Corcione, F, Vettoretto, N, Longo, G, Sorrentino, M, Giuliani, A, Ferrari, G, Taglietti, L, Verzelli, A, Di Cosmo, M, Cavaliere, D, Milone, M, Rausei, S, Ciaccio, G, Tebala, G, Brisinda, G, Berti, S, Millo, P, Boni, L, Guerrieri, M, Persiani, R, Parini, D, Spinelli, A, Genna, M, Bottino, V, Coratti, A, Scala, D, Rivolta, U, Piccoli, M, Talarico, C, Roviello, F, Anastasi, A, Ettorre, G, Montuori, M, Mariani, P, de Manzini, N, Donini, A, Armellino, M, Feo, C, Guerriero, S, Costanzi, A, Marchesi, F, Cicetti, M, Ciano, P, Benedetti, M, Montemurro, L, Mattei, M, Belloni, E, Apa, D, Di Carlo, M, Clementi, M, Bertocchi, E, Masini, G, Altamura, A, Rubichi, F, Cianflocca, D, Migliore, M, Cassini, D, Pandolfini, L, Falsetto, A, Sciuto, A, Pace, U, Bucci, A, Monari, F, Attina, G, Maurizi, A, Simone, M, Giudici, F, Cianchi, F, Baldini, G, Sensi, B, Aprile, A, Soriero, D, Scarinci, A, Capolupo, G, Sisti, V, Ricci, M, Sagnotta, A, Molfino, S, Amodio, P, Cardinali, A, Cicconi, S, Marziali, I, Frazzini, D, Conti, C, Tamini, N, Braga, M, Motter, M, Tirone, G, Martorelli, G, Cacurri, A, Di Marco, C, Marsanic, P, Federico, N, Spampinato, M, Crepaz, L, Andreuccetti, J, Canfora, I, Maggi, G, Chiozza, M, Spoletini, D, Marcellinaro, R, Lisi, G, Bracale, U, Peltrini, R, Di Nuzzo, M, Botteri, E, Santoni, S, Stefanoni, M, Del Vecchio, G, Magistro, C, Ruggiero, S, Birindelli, A, Budassi, A, Zigiotto, D, Solaini, L, Ercolani, G, De Palma, G, Tenconi, S, Locurto, P, Di Cintio, A, Chiarello, M, Cariati, M, Gennai, A, Grivon, M, Cassinotti, E, Ortenzi, M, Biondi, A, De Luca, M, Carrano, F, Fior, F, Ferronetti, A, Giuliani, G, Marino, G, Bertoglio, C, Pecchini, F, Greco, V, Piagnerelli, R, Canonico, G, Colasanti, M, Pinotti, E, Carminati, R, Osenda, E, Graziosi, L, De Martino, C, Ioia, G, Pindozzi, F, Organetti, L, Monteleone, M, Dalmonte, G, La Gioia, G, Catarci M., Guadagni S., Masedu F., Ruffo G., Viola M. G., Borghi F., Baldazzi G., Scatizzi M., Pirozzi F., Delrio P., Garulli G., Marini P., Campagnacci R., De Luca R., Ficari F., Sica G., Scabini S., Liverani A., Caricato M., Patriti A., Mancini S., Baiocchi G. L., Santoro R., Siquini W., Guercioni G., Basti M., Pedrazzani C., Totis M., Carrara A., Lucchi A., Pavanello M., Muratore A., D'Ugo S., Di Leo A., Pignata G., Elmore U., Anania G., Carlini M., Corcione F., Vettoretto N., Longo G., Sorrentino M., Giuliani A., Ferrari G., Taglietti L., Verzelli A., Di Cosmo M., Cavaliere D., Milone M., Rausei S., Ciaccio G., Tebala G., Brisinda G., Berti S., Millo P., Boni L., Guerrieri M., Persiani R., Parini D., Spinelli A., Genna M., Bottino V., Coratti A., Scala D., Rivolta U., Piccoli M., Talarico C., Roviello F., Anastasi A., Ettorre G. M., Montuori M., Mariani P., de Manzini N., Donini A., Armellino M. F., Feo C., Guerriero S., Costanzi A., Marchesi F., Cicetti M., Ciano P., Benedetti M., Montemurro L. A., Mattei M. S., Belloni E., Apa D., Di Carlo M., Clementi M., Bertocchi E., Masini G., Altamura A., Rubichi F., Cianflocca D., Migliore M., Cassini D., Pandolfini L., Falsetto A., Sciuto A., Pace U., Bucci A. F., Monari F., Attina G. M., Maurizi A., Simone M., Giudici F., Cianchi F., Baldini G., Sensi B., Aprile A., Soriero D., Scarinci A., Capolupo G. T., Sisti V., Ricci M. L., Sagnotta A., Molfino S., Amodio P., Cardinali A., Cicconi S., Marziali I., Frazzini D., Conti C., Tamini N., Braga M., Motter M., Tirone G., Martorelli G., Cacurri A., Di Marco C., Marsanic P., Federico N. S. P., Spampinato M., Crepaz L., Andreuccetti J., Canfora I., Maggi G., Chiozza M., Spoletini D., Marcellinaro R., Lisi G., Bracale U., Peltrini R., Di Nuzzo M. M., Botteri E., Santoni S., Stefanoni M., Del Vecchio G., Magistro C., Ruggiero S., Birindelli A., Budassi A., Zigiotto D., Solaini L., Ercolani G., De Palma G. D., Tenconi S., Locurto P., Di Cintio A., Chiarello M. M., Cariati M., Gennai A., Grivon M., Cassinotti E., Ortenzi M., Biondi A., De Luca M., Carrano F., Fior F., Ferronetti A., Giuliani G., Marino G., Bertoglio C. L., Pecchini F., Greco V., Piagnerelli R., Canonico G., Colasanti M., Pinotti E., Carminati R., Osenda E., Graziosi L., De Martino C., Ioia G., Pindozzi F., Organetti L., Monteleone M., Dalmonte G., and La Gioia G.

Abstract

Background: Since most anastomoses after left-sided colorectal resections are performed with a circular stapler, any technological change in stapling devices may influence the incidence of anastomotic adverse events. The aim of the present study was to analyze the effect of a three-row circular stapler on anastomotic leakage and related morbidity after left-sided colorectal resections. Materials and methods: A circular stapled anastomosis was performed in 4255 (50.9%) out of 8359 patients enrolled in two prospective multicenter studies in Italy, and, after exclusion criteria to reduce heterogeneity, 2799 (65.8%) cases were retrospectively analyzed through a 1:1 propensity score-matching model including 20 covariates relative to patient characteristics, to surgery and to perioperative management. Two well-balanced groups of 425 patients each were obtained: group (A) – true population of interest, anastomosis performed with a three-row circular stapler; group (B) – control population, anastomosis performed with a two-row circular stapler. The target of inferences was the average treatment effect in the treated (ATT). The primary endpoints were overall and major anastomotic leakage and overall anastomotic bleeding; the secondary endpoints were overall and major morbidity and mortality rates. The results of multiple logistic regression analyses for the outcomes, including the 20 covariates selected for matching, were presented as odds ratios (OR) and 95% confidence intervals (95% CI). Results: Group A versus group B showed a significantly lower risk of overall anastomotic leakage (2.1 vs. 6.1%; OR 0.33; 95% CI 0.15–0.73; P = 0.006), major anastomotic leakage (2.1 vs. 5.2%; OR 0.39; 95% CI 0.17–0.87; P = 0.022), and major morbidity (3.5 vs. 6.6% events; OR 0.47; 95% CI 0.24–0.91; P = 0.026). Conclusion: The use of three-row circular staplers independently reduced the risk of anastomotic leakage and related morbidity after left-sided colorectal resection. Twenty-five pati

Published
2023

10. Can the endometrioma be an obstacle to complete oocyte retrieval in IVF cycles? A retrospective study.

Author

BALDINI, G. M., LAGANÀ, A. S., MASTROROCCO, A., MALVASI, A., BALDINI, D., FERRI, D., SCIORIO, R., and TROJANO, G.

Abstract

OBJECTIVE: The study aimed to evaluate the utility and safety of ancillary maneuvers during oocyte retrieval for patients with endometrioma that makes ovum pick-up hard due to poor ovarian surgical accessibility. PATIENTS AND METHODS: Cases of 251 women with ovarian endometriomas undergoing in vitro fertilization (IVF) in our infertility unit were retrospectively analyzed to evaluate the clinical IVF cycle outcomes after oocyte retrieval. Controls (n = 251) were age-matched women without endometriomas who underwent an uncomplicated oocyte retrieval. RESULTS: No statistically significant differences were observed between groups except for the number of oocytes retrieved, which was higher in the control group than in the group of women with endometrioma. On the contrary, there were no differences between the experimental groups in the fertilization rate and number of embryos and neither were there in the pregnancy and live birth rate. Moreover, the surgical complications were infrequent and similar between the two analyzed groups. Accidental or voluntary endometrioma punctures were not accompanied by increases in the risk of a pelvic infection. CONCLUSIONS: In conclusion, patients with endometrioma can undergo high-performance oocyte recovery procedures thanks to safe accessory maneuvers during the ovum pick-up. [ABSTRACT FROM AUTHOR]

Published
2024

11. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018

Author

Gustafsson, U. O., Scott, M. J., Hubner, M., Nygren, J., Demartines, N., Francis, N., Rockall, T. A., Young-Fadok, T. M., Hill, A. G., Soop, M., de Boer, H. D., Urman, R. D., Chang, G. J., Fichera, A., Kessler, H., Grass, F., Whang, E. E., Fawcett, W. J., Carli, F., Lobo, D. N., Rollins, K. E., Balfour, A., Baldini, G., Riedel, B., and Ljungqvist, O.

Published
2019
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12. P240 PREOPERATIVE OPTIMISATION FOR A PATIENT WITH HEART FAILURE UNDERGOING MAJOR NON–CARDIAC SURGERY: AN EXAMPLE OF COLLABORATION BETWEEN THE MULTIMODAL PREHABILITATION CENTRE AND THE HEART FAILURE CLINIC AT CAREGGI UNIVERSITY HOSPITAL

Author

Testa, G, primary, Livi, F, additional, Foti, L, additional, Verga, F, additional, Salucci, C, additional, D‘Errico, G, additional, Perini, E, additional, Fiorindi, C, additional, Cianchi, F, additional, Ficari, F, additional, Scaringi, S, additional, Tognozzi, C, additional, Amatucci, S, additional, Marmorale, S, additional, Ungar, A, additional, Romagnoli, S, additional, Orso, F, additional, Baldasseroni, S, additional, and Baldini, G, additional

Published
2023
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15. Indirect structural health monitoring (iSHM) of transport infrastructure in the digital age. MITICA (Monitoring Transport Infrastructures with Connected and Automated vehicles) workshop report

Author

Gkoumas, Konstantinos, Galassi, M.C., Allaix, Diego, Anthonine, A, Argyroudis, S., Baldini, G, Benedetti, Lorenzo, Bono, F, Brownjohn, James, Caetano, Elsa, Camata, G, Cantero, Daniel, Cimellaro, G.P., and Cutini, Maurizio

Abstract

The existing European motorway infrastructure network is prone to ageing and subject to natural events (e.g. climate change) and hazards (e.g. earthquakes), necessitating immediate actions for its maintenance and safety. Within this context, the structural health monitoring (SHM) framework allows a quantitative assessment of the structural integrity, serviceability and performance, facilitating better-informed decisions for the management of the existing infrastructure. The European Commission Joint Research Centre (JRC) established the exploratory research project MITICA (Monitoring Transport Infrastructures with Connected and Automated vehicles) to investigate the opportunity to use novel methods for infrastructure motoring, aiming at the efficient maintenance of the European aging road infrastructure. This report summarizes the discussion and the outcomes of a workshop held at the JRC in Ispra (Italy) on June 6-7 2022, as part of the MITICA project. Considering the EU priority “A Europe fit for the digital age”, the workshop was dedicated to SHM and its application to civil infrastructure, focusing on innovative indirect structural health monitoring (iSHM) approaches that rely on the vehicle-bridge interaction and the deployment of sensor-equipped vehicles for the monitoring of the existing bridge infrastructure. The report aims to become a reference document in the area of iSHM using passing vehicles, for both scholars and policy makers.

Published
2023

18. EP05.02-015 Neoadjuvant Prehabilitation Therapy for Locally Advanced Non-small-Cell Lung Cancer: Optimizing Outcomes throughout the Trajectory of Care

Author

Schmid, S., primary, Minnella, E.M., additional, Pilon, Y., additional, Rokah, M., additional, Rayes, R., additional, Najmeh, S., additional, Cools-Lartigue, J., additional, Ferri, L., additional, Mulder, D., additional, Sirois, C., additional, Owen, S., additional, Shieh, B., additional, Ofiara, L., additional, Wong, A., additional, Sud, S., additional, Baldini, G., additional, Carli, F., additional, and Spicer, J., additional

Published
2022
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19. Obesity does not increase the risk of side effects and complications of egg retrieval: delaying oocyte retrieval in obese patients is not a good strategy.

Author

BALDINI, G. M., LOT, D., HATIRNAZ, S., MALVASI, A., CASCARDI, E., CAZZATO, G., DELLINO, M., BALDINI, D., and TROJANO, G.

Abstract

OBJECTIVE: Obesity is one of the main concerns for public health and is becoming an increasingly widespread problem worldwide. Women are more likely to require a cesarean section and have a longer hospital stay after delivery. Excess body weight can interfere with ovulation and make it more difficult for embryos to implant in the uterus. A high body mass index (BMI) has controversial effects on the outcomes of medically assisted reproduction treatments (IVF) and, if careful counseling is not performed, medical-legal risks may be incurred. While some researchers argue that obesity does not particularly affect ART outcomes, other studies claim that a high BMI does not interfere with embryonic development. Both the American Society for Reproductive Medicine (ASRM) and the European Society of Human Reproduction and Embryology (ESHRE) has stated that there is no clear evidence supporting a BMI limit for IVF treatment and that each patient should be evaluated on an individual basis. The purpose of our study was to evaluate whether performing in vitro fertilization on these patients increases the risk of medical, surgical, and anesthetic complications of oocyte retrieval. PATIENTS AND METHODS: From January 2011 to December 2022, all patients with BMI higher than 25 were enrolled in the study (n=766). Complications and risks related to oocyte retrieval were evaluated, and patients were divided according to BMI groups. RESULTS: With the one-way ANOVA test, all groups were compared with the control group, and none showed statistically significant differences, only the number of produced embryos in the BMI group between 30-34.9 was lower and statistically significant.Only one study has analyzed these aspects, mainly focusing on the need for anesthesia drugs and any related complications, and the same author reported greater difficulty in performing oocyte retrieval. The same study recorded an increase in incomplete oocyte retrievals. Our work does not confirm any of these impressions. [ABSTRACT FROM AUTHOR]

Published
2023

20. 03. Is ethnicity an appropriate measure of health care marginalization?: A systematic review and meta-analysis of the outcomes of diabetic foot ulceration in the Aboriginal population

Author

Johnson, G., Vergis, A., Unger, B., Park, J., Gillman, L., Hickey, K., Pace, D., Azin, A., Guidolin, K., Lam-Tin-Cheung, K., Chadi, S., Quereshy, F., Catton, J., Rubin, B., Bell, J., Marangos, J., Heesters, A., Stuart-McEwan, T., Shariff, F., Wright, F., Ahmed, N., Nadler, A., Hallet, J., Gentles, J., Chen, L., Hwang, H., Parapini, M., Hirpara, D., Sidhu, R., Scott, T., Karimuddin, A., Guo, R., Nguyen, A., Osborn, J., Wiseman, S., Nabata, K., Ertel, E., Lenet, T., Baker, L., Park, L., Vered, M., Zahrai, A., Shorr, R., Davis, A., McIsaac, D., Tinmouth, A., Fergusson, D., Martel, G., Rummel, S., Stefic-Cubic, M., Stewart, M., Melck, A., McKechnie, T., Anpalagan, T., Ichhpuniani, S., Lee, Y., Ramji, K., Eskicioglu, C., Zhu, A., Deng, S., Greene, B., Tsang, M., Palter, V., Jayaraman, S., Mann, A., Tittley, J., Cadeddu, M., Nguyen, M., Madani, A., Pasternak, J., Hong, D., Qu, L., Istl, A., Tang, E., Gray, D., Zuckerman, J., Coburn, N., Callum, J., McLeod, R., Pearsall, E., Lin, Y., Turgeon, A., Mahar, A., Kammili, A., Kriviraltcheva-Kaneva, P., Lee, L., Cools-Lartigue, J., Ferri, L., Mueller, C., Haas, B., Tillman, B., Guttman, M., Chesney, T., Zuk, V., Hsu, A., Chan, W., Vasdev, R., D’Souza, K., Huynh, C., Ling, L. Cadili J., Warburton, R., Hameed, M., Glass, L., Williamson, H., Murphy, P., Leslie, K., Hawel, J., Kerr, L., Zablotny, S., Roldan, H., He, W., Jiang, X., Zheng, B., Fiore, J., Feldman, L., Fried, G., Valanci, S., Balvardi, S., Cipolla, J., Kaneva, P., Demyttenaere, S., Boutros, M., Alhashemi, M., Miles, A., Purich, K., Verhoeff, K., Shapiro, J., Bigam, D., Kung, J., Fecso, A., Mosko, J., Skubleny, D., Hamilton, P., Ghosh, S., Widder, S., Schiller, D., Do, U., El Kefraoui, C., Pook, M., Barone, N., Montgomery, H., Nguyen-Powanda, P., Rajabiyazdi, F., Elhaj, H., Lapointe-Gagner, M., Olleik, G., Antoun, A., Safa, N., Di Lena, E., Meterissian, S., Meguerditchian, A., Lee, F., Baldini, G., Serrano Aybar, P.E., Parpia, S., Ruo, L., Tywonek, K., Lee, S., O’Neill, C., Faisal, N., Alfayyadh, A., Gundayao, M., Meyers, B.M., Habashi, R., Kruse, C., Levin, M., Aldrich, K., Grantcharov, T., Langerman, A., Forbes, H., Anantha, R., Fawcett, V., Hetherington, A., Pravong, V., Gervais, M., Rakovich, G., Selvam, R., Hu, R., Musselman, R., Raiche, I., Moloo, H., Liu, R., Elnahas, A., Alkhamesi, N., Alnumay, A., Schlachta, C., Walser, E., Zhang, C., Cristancho, S., Ott, M., Lee, A., Niu, B., Balaa, F., Gawad, N., Ren, K., Qiu, Y., Hamann, K., How, N., Leveille, C., Davidson, A., Eqbal, A., Sardiwalla, Y., Korostensky, M., Lee, E., Yang, I., Muaddi, H., Stukel, T., de Mestral, C., Nathens, A., Karanicolas, P., Frigault, J., Lemieux, S., Breton, D., Bouchard, P., Bouchard, A., Grégoire, R., Letarte, F., Bouchard, G., Drolet, S., Avoine, S., Gagné, J., Thibault, C., Jutras Bouthillette, N., Gosselin, M., Rosenzveig, A., Stuleanu, T., Jarrar, A., Kolozsvari, N., Skelhorne-Gross, G., Nenshi, R., Jerath, A., Gomez, D., Singh, K., Amir, T., Liu, E., Farquharson, S., Mao, R., Lan, L., Yan, J., Allard-Coutu, A., Mierzwa, A., Tin, R., Brisebois, R., Bradley, N., Wigen, R., Hartford, L., Van Koughnett, J., Vogt, K., Hilsden, R., Parry, N., Allen, L., Raskin, R., Jones, J., Neumann, K., Dwyer, C., Strickland, M., O’Dochartaigh, D., Lobay, K., Kabaroff, A., Chang, E., Sun, W., Beck, J., Davidson, J., Jones, S., Van Hooren, T., Schmitz, E., El Hafid, M., Dang, J., Mocanu, V., Lutzak, G., Sultanian, R., Wong, C., Karmali, S., Petrera, M., Pickell, M., Auer, R., Patro, N., Li, B., Wilson, H., Jogiat, U., Switzer, N., Li, C., Al Hinai, A., Cieply, A., Hawes, H., Joos, E., Saleh, A., Engels, P., Drung, J., Pang, G., Kwong, M., Ellsmere, J., Chang, D., Hutter, M., Spence, R., Abou Khalil, M., Vasilevsky, C., Morin, N., Longtin, Y., Liberman, S., Montpetit, P., Poirier, M., Mukherjee, K., Sebajang, H., Younan, R., Schwenter, F., De Broux, E., Larsen, K., Beckett, A., Nantais, J., Kay, J., Lohre, R., Ayeni, O., Goel, D., de SA, D., He, R., Hylton, D., Bedard, E., Johnson, S., Laing, B., Valji, A., Hanna, W., Turner, S., Akhtar-Danesh, G., Akhtar-Danesh, N., Shargall, Y., Gupta, V., Kidane, B., Limbachia, J., Sullivan, K., Farrokhyar, F., Leontiadis, G., Patel, Y., Churchill, I., Xie, F., Seely, A., Spicer, J., Yasufuku, K., Beauchamp, M., Wald, J., Mbuagbaw, L., Agzarian, J., Finley, C., Fahim, C., Abbas, M., Olaiya, O., Begum, H., Ednie, A., Palma, D., Warner, A., Malthaner, R., Fortin, D., Qiabi, M., Nayak, R., Nguyen, T., Louie, A., Rodrigues, G., Yaremko, B., Laba, J., Inculet, R., Alaichi, J., Mador, B., Lai, H., White, J., Kim, M., Darling, G., Rousseau, M., Samarasinghe, Y., Lee, M., Thiru, L., Levine, O., Juergens, R., Brogly, S., Li, W., Lougheed, D., Petsikas, D., Mistry, N., Gatti, A., Abdul, S., Anestee, C., Gilbert, S., Sundaresan, S., Villeneuve, P., Maziak, D., Razzak, R., Ashrafi, A., Tregobov, N., Hassanzadeh, N., Stone, S., Panjwani, A., Bong, T., Bond, R., Hafizi, A., De Meo, M., Rayes, R., Milette, S., Vagai, M., Usatii, M., Chandrasekaran, A., Giannias, B., Bourdeau, F., Sangwan, V., Bertos, N., Moraes, C., Huang, S., Quail, D., Walsh, L., Camilleri-Broet, S., Fiset, P., Bilgic, E., Quaiattini, A., Maurice-Ventouris, M., Najmeh, S., Esther, L., 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K., Enns, S., Tan, A., Bruinooge, A., Poole, E., Pascoe, C., Karakach, T., Halayko, A., Fang, B., Birch, D., Singh, H., Hershorn, O., Hochman, D., Helewa, R., Robertson, R., Cahill, C., Lipson, M., Afzal, A., Maclean, A., Roen, S., Buie, W., Chu, M., Amin, N., Jaffer, H., Rebello, R., Doumouras, A., Hajjar, R., Oliero, M., Cuisiniere, T., Fragoso, G., Calvé, A., Djediai, S., Annabi, B., Richard, C., Santos, M., Zhou, Y., Dodd), S., Ring, B., Yuan, Y., Garfinkle, R., Dell’Aniello, S., Bhatnagar, S., Ghitulescu, G., Faria, J., Brassard, P., Salama, E., Amar-Zifkin, A., Talwar, G., Daniel, R., AlSulaim, H., Alqahtani, M., Al-Masrouri, S., Chen, A., Patel, A., Brissette, V., Al Busaidi, N., Moon, J., Demian, M., MacRae, H., Alam, F., Holland, J., Cwintal, M., Rigas, G., Pang, A., Marinescu, D., Brown, C., Raval, M., Phang, P., Ghuman, A., Li, M., Muncner, S., Mihajlovic, I., Dykstra, M., Snelgrove, R., Monton, O., Smith, A., AlAamer, O., AlSelaim, N., AlMalki, M., Al-osail, A., Ruxton, R., 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Subjects
Abstracts, Canadian Association of General Surgeons, Canadian Hernia Society, Canada, Canadian Association of Thoracic Surgeons, Canadian Hepato-Pancreato-Biliary Association, Humans, Canadian Society of Surgical Oncology, Canadian Association of Bariatric Physicians and Surgeons, Canadian Society of Colon and Rectal Surgeons
Published
2022

21. Fare causa alla Cina per il virus, una corsa ad ostacoli

Author

Armano, A., Baldini, G., Bona, M., Ceccherini, G., Cendon, P., Clemente, A., Franzina, P., Graziadei, M., Marcatajo, G., Meli, M., Negro, A., Rossi, S., Salanitro, U., Spangher, G., Todeschini, N., Venchiarutti, A., Ziviz, P., Franzina, P. (ORCID:0000-0001-9601-2281), Armano, A., Baldini, G., Bona, M., Ceccherini, G., Cendon, P., Clemente, A., Franzina, P., Graziadei, M., Marcatajo, G., Meli, M., Negro, A., Rossi, S., Salanitro, U., Spangher, G., Todeschini, N., Venchiarutti, A., Ziviz, P., and Franzina, P. (ORCID:0000-0001-9601-2281)

Abstract

Lo scritto, di taglio divulgativo, ripercorre le questioni giuridiche che dovrebbe affrontare chi volesse far accertare in giudizio in Italia, in sede civile, un'ipotetica responsabilità della Repubblica Popolare Cinese per i danni provocati dalla diffusione del virus SARS-CoV-2.

Published
2022

22. Evaluation of the ideal vaginal Progesterone effectiveness doses for luteal support in embryo thawing cycles after endometrial preparation without using the GnRh analogue.

Author

BALDINI, G. M., MASTROROCCO, A., HATIRNAZ, S., MALVASI, A., CAZZATO, G., CASCARDI, E., DELLINO, M., and BALDINI, D.

Abstract

OBJECTIVE: Frozen-thawed embryo transfer (FET) cycles require the use of luteal phase support (LPS) for supporting implantation, endometrial and embryo maturity. Individualized LPS should be chosen according to the used endometrial preparation protocol. The aim of the study was to analyze the effectiveness of two different vaginal Progesterone doses for women who underwent FET cycle and the same endometrial preparation without using the GnRh analogue. PATIENTS AND METHODS: 607 women who underwent FET cycle were included in the study. 305 patients received luteal support with 600 mg/day vaginal Progesterone and 302 patients were treated with 800 mg/day of vaginal Progesterone. RESULTS: In the 800 mg/day group, the mean serum Progesterone concentration on the day of embryo transfer was higher than in the 600 mg group (14.00±6.18 ng/mL and 12.22±5.39, respectively, p < 0.001). Moreover, human chorionic gonadotrophin (hCG) positive and ongoing pregnancy rates were higher in the group of patients who received LPS with 800 mg/day of Progesterone than in the group of patients treated with 600 mg/day of Progesterone. CONCLUSIONS: In patients undergoing FET cycles following endometrial preparation made without previously using the GnRh analogue, 800 mg doses of vaginal Progesterone as LPS improve reproductive outcomes. [ABSTRACT FROM AUTHOR]

Published
2023

23. An Atlas for the Inkjet Printing of Large-Area Tactile Sensors

Author

Baldini, G, Albini, A, Maiolino, P, and Cannata, G

Subjects
Inkjet printing, Large area, Robotic, Tactile sensors, Electronics, Touch, Electrical and Electronic Engineering, Biochemistry, Instrumentation, Atomic and Molecular Physics, and Optics, Analytical Chemistry
Abstract

This review aims to discuss the inkjet printing technique as a fabrication method for the development of large-area tactile sensors. The paper focuses on the manufacturing techniques and various system-level sensor design aspects related to the inkjet manufacturing processes. The goal is to assess how printed electronics simplify the fabrication process of tactile sensors with respect to conventional fabrication methods and how these contribute to overcoming the difficulties arising in the development of tactile sensors for real robot applications. To this aim, a comparative analysis among different inkjet printing technologies and processes is performed, including a quantitative analysis of the design parameters, such as the costs, processing times, sensor layout, and general system-level constraints. The goal of the survey is to provide a complete map of the state of the art of inkjet printing, focusing on the most effective topics for the implementation of large-area tactile sensors and a view of the most relevant open problems that should be addressed to improve the effectiveness of these processes.

Published
2022

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Author

Johnson, G., primary, Hickey, K., primary, Azin, A., primary, Guidolin, K., primary, Shariff, F., primary, Gentles, J., primary, Parapini, M., primary, Guo, R., primary, Ertel, E., primary, Lenet, T., primary, Nabata, K., primary, McKechnie, T., primary, Zhu, A., primary, Nguyen, M., primary, Qu, L., primary, Zuckerman, J., primary, Kammili, A., primary, D’Souza, K., primary, Glass, L., primary, Kerr, L., primary, He, W., primary, Lee, L., primary, Balvardi, S., primary, Miles, A., primary, Fecso, A., primary, Skubleny, D., primary, Do, U., primary, Serrano Aybar, P.E., primary, Kruse, C., primary, Forbes, H., primary, Pravong, V., primary, Selvam, R., primary, Liu, R., primary, Walser, E., primary, Lee, A., primary, Ren, K., primary, Muaddi, H., primary, Frigault, J., primary, Rosenzveig, A., primary, Skelhorne-Gross, G., primary, Singh, K., primary, Mierzwa, A., primary, Wigen, R., primary, Raskin, R., primary, Dwyer, C., primary, Sun, W., primary, Schmitz, E., primary, Patro, N., primary, Wilson, H., primary, Li, C., primary, Drung, J., primary, Pang, G., primary, Abou Khalil, M., primary, Larsen, K., primary, Lan, L., primary, He, R., primary, Akhtar-Danesh, G., primary, Hirpara, D., primary, Sullivan, K., primary, Jogiat, U., primary, Patel, Y., primary, Abbas, M., primary, Ednie, A., primary, Alaichi, J., primary, Turner, S., primary, Lee, Y., primary, Nayak, R., primary, Mistry, N., primary, Abdul, S., primary, Razzak, R., primary, De Meo, M., primary, Esther, L., primary, Brophy, S., primary, Resende, V., primary, Sisson, D., primary, Alghamedi, A., primary, Shargall, Y., primary, Greenberg, B., primary, Huynh, C., primary, Al Rawahi, A., primary, Humer, M., primary, Le Nguyen, D., primary, Kaafarani, M., primary, Hunka, N., primary, Churchill, I., primary, Finley, C., primary, Jones, D., primary, Gupta, V., primary, Peters, E., primary, Robinson, M., primary, Wang, H., primary, Graham, K., primary, Bruinooge, A., primary, Verhoeff, K., primary, Cahill, C., primary, Hajjar, R., primary, Purich, K., primary, Garfinkle, R., primary, Talwar, G., primary, AlSulaim, H., primary, Brissette, V., primary, Holland, J., primary, Brown, C., primary, Li, M., primary, Monton, O., primary, AlAamer, O., primary, Ruxton, R., primary, Motamedi, M.K., primary, Caminsky, N., primary, Bayat, Z., primary, Liang, J., primary, Roy, H., primary, Moon, J., primary, Salama, E., primary, Wiseman, V., primary, Harra, Z., primary, Hegagi, M., primary, Alghaithi, N., primary, Papillon, E., primary, Kasteel, N., primary, Szwimer, R., primary, Merchant, S., primary, Li, V., primary, Jacobson, M., primary, Marini, W., primary, DiPasquale, A., primary, Gagnon, N., primary, Mysuria), S., primary, Hunter-Smith, A., primary, Alqaydi, A., primary, Di Lena, É., primary, Mysuria, S., primary, Kapur, H., primary, Cadili, L., primary, Ng, D., primary, Allen, K., primary, Cyr, D., primary, Allard-Coutu, A., primary, Mardinger, C., primary, Nguyen, D., primary, Langer, S., primary, Lim, D., primary, Reyna-Sepulveda, F., primary, Hanna, N., primary, Henault, D., primary, Lemke, M., primary, Lund, M., primary, Park, L., primary, Glinka, J., primary, Waugh, E., primary, Webb, A., primary, Essaji, Y., primary, Shrader, H., primary, Smith, V., primary, Gilbert, R., primary, Mir, Z., primary, Elbekri, S., primary, Zuker, N., primary, Chartrand, G., primary, Melland-Smith, M., primary, McLean, C., primary, Fortin, M., primary, Keshavjee, S., primary, Deaninck, F., primary, Cloutier, Z., primary, Shiroky, J., primary, Jarrar, A., primary, Lin, W., primary, Connell, M., primary, Vergis, A., additional, Unger, B., additional, Park, J., additional, Gillman, L., additional, Pace, D., additional, Lam-Tin-Cheung, K., additional, Chadi, S., additional, Quereshy, F., additional, Catton, J., additional, Rubin, B., additional, Bell, J., additional, Marangos, J., additional, Heesters, A., additional, Stuart-McEwan, T., additional, Wright, F., additional, Ahmed, N., additional, Nadler, A., additional, Hallet, J., additional, Chen, L., additional, Hwang, H., additional, Hirpara, D., additional, Sidhu, R., additional, Scott, T., additional, Karimuddin, A., additional, Nguyen, A., additional, Osborn, J., additional, Wiseman, S., additional, Nabata, K., additional, Baker, L., additional, Park, L., additional, Vered, M., additional, Zahrai, A., additional, Shorr, R., additional, Davis, A., additional, McIsaac, D., additional, Tinmouth, A., additional, Fergusson, D., additional, Martel, G., additional, Rummel, S., additional, Stefic-Cubic, M., additional, Stewart, M., additional, Melck, A., additional, Anpalagan, T., additional, Ichhpuniani, S., additional, Lee, Y., additional, Ramji, K., additional, Eskicioglu, C., additional, Deng, S., additional, Greene, B., additional, Tsang, M., additional, Palter, V., additional, Jayaraman, S., additional, Mann, A., additional, Tittley, J., additional, Cadeddu, M., additional, Madani, A., additional, Pasternak, J., additional, Hong, D., additional, Istl, A., additional, Tang, E., additional, Gray, D., additional, Coburn, N., additional, Callum, J., additional, McLeod, R., additional, Pearsall, E., additional, Lin, Y., additional, Turgeon, A., additional, Mahar, A., additional, Kriviraltcheva-Kaneva, P., additional, Lee, L., additional, Cools-Lartigue, J., additional, Ferri, L., additional, Mueller, C., additional, Haas, B., additional, Tillman, B., additional, Guttman, M., additional, Chesney, T., additional, Zuk, V., additional, Hsu, A., additional, Chan, W., additional, Vasdev, R., additional, Huynh, C., additional, Ling, L. Cadili J., additional, Warburton, R., additional, Hameed, M., additional, Williamson, H., additional, Murphy, P., additional, Leslie, K., additional, Hawel, J., additional, Zablotny, S., additional, Roldan, H., additional, Jiang, X., additional, Zheng, B., additional, Fiore, J., additional, Feldman, L., additional, Fried, G., additional, Valanci, S., additional, Cipolla, J., additional, Kaneva, P., additional, Demyttenaere, S., additional, Boutros, M., additional, Alhashemi, M., additional, Purich, K., additional, Verhoeff, K., additional, Shapiro, J., additional, Bigam, D., additional, Kung, J., additional, Mosko, J., additional, Hamilton, P., additional, Ghosh, S., additional, Widder, S., additional, Schiller, D., additional, El Kefraoui, C., additional, Pook, M., additional, Barone, N., additional, Balvardi, S., additional, Montgomery, H., additional, Nguyen-Powanda, P., additional, Rajabiyazdi, F., additional, Elhaj, H., additional, Lapointe-Gagner, M., additional, Olleik, G., additional, Antoun, A., additional, Safa, N., additional, Di Lena, E., additional, Meterissian, S., additional, Meguerditchian, A., additional, Lee, F., additional, Baldini, G., additional, Parpia, S., additional, Ruo, L., additional, Tywonek, K., additional, Lee, S., additional, O’Neill, C., additional, Faisal, N., additional, Alfayyadh, A., additional, Gundayao, M., additional, Meyers, B.M., additional, Habashi, R., additional, McKechnie, T., additional, Levin, M., additional, Aldrich, K., additional, Grantcharov, T., additional, Langerman, A., additional, Anantha, R., additional, Fawcett, V., additional, Hetherington, A., additional, Gervais, M., additional, Rakovich, G., additional, Hu, R., additional, Musselman, R., additional, Raiche, I., additional, Moloo, H., additional, Elnahas, A., additional, Alkhamesi, N., additional, Alnumay, A., additional, Schlachta, C., additional, Zhang, C., additional, Cristancho, S., additional, Ott, M., additional, Niu, B., additional, Balaa, F., additional, Gawad, N., additional, Qiu, Y., additional, Hamann, K., additional, How, N., additional, Leveille, C., additional, Davidson, A., additional, Eqbal, A., additional, Sardiwalla, Y., additional, Korostensky, M., additional, Lee, E., additional, Yang, I., additional, Ren, K., additional, Stukel, T., additional, de Mestral, C., additional, Nathens, A., additional, Karanicolas, P., additional, Lemieux, S., additional, Breton, D., additional, Bouchard, P., additional, Bouchard, A., additional, Grégoire, R., additional, Letarte, F., additional, Bouchard, G., additional, Drolet, S., additional, Avoine, S., additional, Gagné, J., additional, Thibault, C., additional, Jutras Bouthillette, N., additional, Gosselin, M., additional, Stuleanu, T., additional, Jarrar, A., additional, Kolozsvari, N., additional, Nenshi, R., additional, Jerath, A., additional, Gomez, D., additional, Amir, T., additional, Liu, E., additional, Farquharson, S., additional, Mao, R., additional, Lan, L., additional, Yan, J., additional, Allard-Coutu, A., additional, Tin, R., additional, Brisebois, R., additional, Bradley, N., additional, Walser, E., additional, Hartford, L., additional, Van Koughnett, J., additional, Vogt, K., additional, Hilsden, R., additional, Parry, N., additional, Allen, L., additional, Jones, J., additional, Neumann, K., additional, Strickland, M., additional, O’Dochartaigh, D., additional, Lobay, K., additional, Kabaroff, A., additional, Chang, E., additional, Beck, J., additional, Davidson, J., additional, Jones, S., additional, Van Hooren, T., additional, El Hafid, M., additional, Dang, J., additional, Mocanu, V., additional, Lutzak, G., additional, Sultanian, R., additional, Wong, C., additional, Karmali, S., additional, Petrera, M., additional, Pickell, M., additional, Auer, R., additional, Li, B., additional, Sun, W., additional, Jogiat, U., additional, Switzer, N., additional, Al Hinai, A., additional, Cieply, A., additional, Hawes, H., additional, Joos, E., additional, Saleh, A., additional, Engels, P., additional, Kwong, M., additional, Ellsmere, J., additional, Chang, D., additional, Hutter, M., additional, Spence, R., additional, Vasilevsky, C., additional, Morin, N., additional, Longtin, Y., additional, Liberman, S., additional, Montpetit, P., additional, Poirier, M., additional, Mukherjee, K., additional, Sebajang, H., additional, Younan, R., additional, Schwenter, F., additional, De Broux, E., additional, Skelhorne-Gross, G., additional, Beckett, A., additional, Nantais, J., additional, Kay, J., additional, Lohre, R., additional, Ayeni, O., additional, Goel, D., additional, de SA, D., additional, Hylton, D., additional, Bedard, E., additional, Johnson, S., additional, Laing, B., additional, Valji, A., additional, Hanna, W., additional, Turner, S., additional, Akhtar-Danesh, N., additional, Shargall, Y., additional, Gupta, V., additional, Kidane, B., additional, Limbachia, J., additional, Farrokhyar, F., additional, Leontiadis, G., additional, Patel, Y., additional, Churchill, I., additional, Xie, F., additional, Seely, A., additional, Spicer, J., additional, Yasufuku, K., additional, Sullivan, K., additional, Beauchamp, M., additional, Wald, J., additional, Mbuagbaw, L., additional, Agzarian, J., additional, Finley, C., additional, Fahim, C., additional, Olaiya, O., additional, Begum, H., additional, Palma, D., additional, Warner, A., additional, Malthaner, R., additional, Fortin, D., additional, Qiabi, M., additional, Nayak, R., additional, Nguyen, T., additional, Louie, A., additional, Rodrigues, G., additional, Yaremko, B., additional, Laba, J., additional, Inculet, R., additional, Mador, B., additional, Lai, H., additional, White, J., additional, Kim, M., additional, Darling, G., additional, Rousseau, M., additional, Samarasinghe, Y., additional, Lee, M., additional, Thiru, L., additional, Levine, O., additional, Juergens, R., additional, Brogly, S., additional, Li, W., additional, Lougheed, D., additional, Petsikas, D., additional, Gatti, A., additional, Anestee, C., additional, Gilbert, S., additional, Sundaresan, S., additional, Villeneuve, P., additional, Maziak, D., additional, Ashrafi, A., additional, Tregobov, N., additional, Hassanzadeh, N., additional, Stone, S., additional, Panjwani, A., additional, Bong, T., additional, Bond, R., additional, Hafizi, A., additional, Rayes, R., additional, Milette, S., additional, Vagai, M., additional, Usatii, M., additional, Chandrasekaran, A., additional, Giannias, B., additional, Bourdeau, F., additional, Sangwan, V., additional, Bertos, N., additional, Moraes, C., additional, Huang, S., additional, Quail, D., additional, Walsh, L., additional, Camilleri-Broet, S., additional, Fiset, P., additional, Bilgic, E., additional, Quaiattini, A., additional, Maurice-Ventouris, M., additional, Najmeh, S., additional, Lu, J., additional, Malhan, R., additional, Brennan, K., additional, French, D., additional, Momtazi, M., additional, Solaja, O., additional, Donahoe, L., additional, Bedard, P., additional, Hansen, A., additional, De Perrot, M., additional, Simone, A., additional, Huang, J., additional, Murthy, S., additional, Lin, J., additional, Li, H., additional, Crowther, M., additional, Linkins, L., additional, Lau, E., additional, Schneider, L., additional, Douketis, J., additional, Allen-Avodabo, C., additional, Davis, L., additional, Zhao, H., additional, Sirois, C., additional, Mulder, D., additional, Aftab Abdul, S., additional, Nguyen, D., additional, Anstee, C., additional, Delic, E., additional, Sasewich, H., additional, Islam, T., additional, Low, D., additional, Al Rawahi, A., additional, Kay, M., additional, Shayegan, B., additional, Adili, A., additional, Chouiali, F., additional, Muthukrishnan, N., additional, Maleki, F., additional, Ovens, K., additional, Gold, M., additional, Sorin, M., additional, Falutz, R., additional, Forghani, R., additional, Kennedy, R., additional, Bigsby, R., additional, 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additional, Kruse, C., additional, Jaffer, H., additional, Rebello, R., additional, Doumouras, A., additional, Oliero, M., additional, Cuisiniere, T., additional, Fragoso, G., additional, Calvé, A., additional, Djediai, S., additional, Annabi, B., additional, Richard, C., additional, Santos, M., additional, Zhou, Y., additional, Dodd), S., additional, Ring, B., additional, Yuan, Y., additional, Dell’Aniello, S., additional, Bhatnagar, S., additional, Ghitulescu, G., additional, Faria, J., additional, Brassard, P., additional, Salama, E., additional, Amar-Zifkin, A., additional, Daniel, R., additional, Alqahtani, M., additional, Garfinkle, R., additional, Al-Masrouri, S., additional, Chen, A., additional, Patel, A., additional, Al Busaidi, N., additional, Moon, J., additional, Demian, M., additional, MacRae, H., additional, Alam, F., additional, Cwintal, M., additional, Rigas, G., additional, Pang, A., additional, Marinescu, D., additional, Raval, M., additional, Phang, P., additional, 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Published
2021
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32. In patients with isthmocele undergoing IVF, the risk of ectopic pregnancy on the cesarean scar is reduced only if the ultrasound-guided transfer is performed on day 5 - A retrospective case-control study.

Author

BALDINI, G. M., MALVASI, A., HATIRNAZ, S., KOSMAS, I., TINELLI, A., and BALDINI, D.

Abstract

OBJECTIVE: The study aimed to demonstrate that the risk of Cesarean Scar Pregnancy (CSP) for patients with isthmocele decreases when the embryo transfer is performed on day 5 at the blastocyst stage. PATIENTS AND METHODS: From January 2014 to December 2021, 167 patients who previously had an IVF treatment and delivered by cesarean section, were selected. The isthmocele was found in 98 of them. Firstly, we evaluated whether the isthmocele increases the risk of CSP. Subsequently, we investigated the possible correlation between the risk of the CSP with the day of the embryo transfer. Hence, the selected patients were divided into two groups: Group A where the embryo transfer was performed at the cleavage stage on day 3 and Group B where the embryo was transferred at the blastocyst stage on day 5. RESULTS: The outcomes show that the isthmocele does not seem to increase the risk of CSP, while the embryo transfer on day 3 increases its rate. CONCLUSIONS: When the isthmocele is diagnosed, according to our results, an embryo transfer on day 5 at the blastocyst stage seems to minimize the risk of the CSP. [ABSTRACT FROM AUTHOR]

Published
2022

33. Lamellar and «club-shaped» corpuscular nerve endings in human gingival mucosa. A light and electron microscopic study

Author

Narducci, P, Zweyer, M, Bareggi, R, Sandrucci, M.A, Baldini, G, and Grill, V

Subjects
histology, histologie, microscopie électronique à transmission, corpuscular nerve endings, terminaisons nerveuses corpusculaires, TEM, muqueuse gingivale humaine, human gingival mucosa
Abstract

A study on the presence of corpuscular nerve endings in human gingival mucosa was performed using both light and transmission electron microscopic (TEM) techniques. Both round and oval lamellar corpuscles were detected by light microscopy. They were located either subepithelially, close to the basement membrane, or within the papillae, deeply invaginated into the overlying epithelium. TEM techniques showed convoluted structures with unmyelinated fibre arborizations leading to an afferent fibre supported by the so called lamellar cells. The presence of blood vessels, collagenous fibrils, desmosome-like junctions, cytoplasmic organelles, as well as the similarity with some previously described mechanoreceptors, suggested the role of such corpuscular nerve endings in transmitting a nervous impulse induced by mechanical stimulation. Other simpler structures were also observed and named «club-shaped» corpuscles: they could support the more complex ones in responding to the strengths and the movements directly influencing the gingival mucosa., La présence de terminaisons nerveuses corpusculaires dans la muqueuse gingivale humaine a été observée tant en microscopie optique qu’en microscopie électronique à transmission. En microscopie optique on a remarqué des corpuscules lamellaires ronds et ovalaires, qui étaient localisés tant au dessous de l’épithélium, tout près de la membrane basale, qu’au dedans des papilles, profondément insérés dans l’épithélium.En microscopie électronique on a observé des structures convolutées pourvues d’arborisations de fibres nerveuses sans myéline qui vont se réunir dans une fibre afférente supportée par des cellules dites lamellaires. La présence de vaisseaux, de fibrilles collagènes, de jonctions telles que desmoses, d’inclusions cytoplasmiques autant que la ressemblance avec quelques mécanorécepteurs décrits en littérature, suggérait un rôle de ces terminaisons nerveuses corpusculaires en envoyant un impulse nerveux induit par une stimulation mécanique. On a aussi observé des corpuscules plus simples appelés «club-shaped» qui pourraient supporter les plus complexes dans la réponse aux forces et aux mouvements qui influencent directement la muqueuse gingivale.

Published
2020

34. The abortion rate in trans-myometrial eggs retrieval is the same as in classical transvaginal retrieval.

Author

BALDINI, G. M., TOTARO, P., MALVASI, A., and BALDINI, D.

Abstract

OBJECTIVE: This study compares the miscarriage rate of pregnancies after trans-myometrial eggs retrieval to transvaginal eggs retrieval. PATIENTS AND METHODS: In the period between January 2004 and December 2020, 13,323 egg retrievals were carried out. In 699 cases, the ovaries were unreachable. Alternative maneuvers were performed to solve this problem, but despite this, in 132 patients the technique of trans-myometrial sampling had to be used. 26 patients were excluded from the study, because of the inclusion criteria, and therefore two groups of 106 patients were selected, Group A and Group B (control). RESULTS: In the comparison between the two groups, there were no statistically significant differences in abortion rates, pregnancy rates and complications after the technique. CONCLUSIONS: This study shows that the abortion rate in trans-myometrial oocyte retrieval does not change when compared to classic retrieval, despite the sampling needle completely crossing the myometrium. Furthermore, the pregnancy rate and the complication rate do not appear to have worsened with this technique. [ABSTRACT FROM AUTHOR]

Published
2022

41. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018

Author

Gustafsson, U.O., Scott, M.J., Hubner, M., Nygren, J., Demartines, N., Francis, N., Rockall, T.A., Young-Fadok, T.M., Hill, A.G., Soop, M., de Boer, H.D., Urman, R.D., Chang, G.J., Fichera, A., Kessler, H., Grass, F., Whang, E.E., Fawcett, W.J., Carli, F., Lobo, D.N., Rollins, K.E., Balfour, A., Baldini, G., Riedel, B., and Ljungqvist, O.

Abstract

This is the fourth updated Enhanced Recovery After Surgery (ERAS ® ) Society guideline presenting a consensus for optimal perioperative care in colorectal surgery and providing graded recommendations for each ERAS item within the ERAS ® protocol. A wide database search on English literature publications was performed. Studies on each item within the protocol were selected with particular attention paid to meta-analyses, randomised controlled trials and large prospective cohorts and examined, reviewed and graded according to Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. All recommendations on ERAS ® protocol items are based on best available evidence; good-quality trials; meta-analyses of good-quality trials; or large cohort studies. The level of evidence for the use of each item is presented accordingly. The evidence base and recommendation for items within the multimodal perioperative care pathway are presented by the ERAS ® Society in this comprehensive consensus review.

Published
2019

44. Goal-directed Fluid Therapy Does Not Reduce Primary Postoperative Ileus after Elective Laparoscopic Colorectal Surgery: A Randomized Controlled Trial

Author

Gomez-Izquierdo J. C., Trainito A., Mirzakandov D., Stein B. L., Liberman S., Charlebois P., Pecorelli N., Feldman L. S., Carli F., Baldini G., Gomez-Izquierdo, J. C., Trainito, A., Mirzakandov, D., Stein, B. L., Liberman, S., Charlebois, P., Pecorelli, N., Feldman, L. S., Carli, F., and Baldini, G.

Subjects
Male, Canada, Ileus, Postoperative Complications, Treatment Outcome, Elective Surgical Procedures, Fluid Therapy, Humans, Female, Laparoscopy, Intestine, Large, Middle Aged, Goals
Abstract

Background: Inadequate perioperative fluid therapy impairs gastrointestinal function. Studies primarily evaluating the impact of goal-directed fluid therapy on primary postoperative ileus are missing. The objective of this study was to determine whether goal-directed fluid therapy reduces the incidence of primary postoperative ileus after laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Methods: Randomized patient and assessor-blind controlled trial conducted in adult patients undergoing laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Patients were assigned randomly to receive intraoperative goal-directed fluid therapy (goal-directed fluid therapy group) or fluid therapy based on traditional principles (control group). Primary postoperative ileus was the primary outcome. Results: One hundred twenty-eight patients were included and analyzed (goal-directed fluid therapy group: N = 64; control group: N = 64). The incidence of primary postoperative ileus was 22% in the goal-directed fluid therapy and 22% in the control group (relative risk, 1; 95% CI, 0.5 to 1.9; P = 1.00). Intraoperatively, patients in the goal-directed fluid therapy group received less intravenous fluids (mainly less crystalloids) but a greater volume of colloids. The increase of stroke volume and cardiac output was more pronounced and sustained in the goal-directed fluid therapy group. Length of hospital stay, 30-day postoperative morbidity, and mortality were not different. Conclusions: Intraoperative goal-directed fluid therapy compared with fluid therapy based on traditional principles does not reduce primary postoperative ileus in patients undergoing laparoscopic colorectal surgery in the context of an Enhanced Recovery After Surgery program. Its previously demonstrated benefits might have been offset by advancements in perioperative care.

Published
2017

45. Increased bioavailability of Vitamin D improved pregnancy outcomes in in vitro fertilization cycles, only in patients over 36 years: a cross-sectional study.

Author

BALDINI, D., MALVASI, A., KOSMAS, I., BALDINI, G. M., and SILVESTRIS, E.

Abstract

OBJECTIVE: Vitamin D (VitD) is a secosteroid hormone showing both antiproliferative and immunomodulatory effects. Its involvement in placental steroidogenesis and endometrial decidualization even plays a role in other gynecological functions, including assisted reproductive technology (ART). However, controversial data have been reported on its implication in pregnancy outcomes during In Vitro Fertilization (IVF) program. In order to elucidate the VitD role in ART success, we evaluated serum and follicular fluid (FF) VitD levels in infertile women concerning the pregnancy rate. PATIENTS AND METHODS: In our IVF center, 446 patients, under the age of 42 years old, were evaluated in the period between January 2018 and December 2019. It is here important to clarify that, in order to respect the exclusion criteria, only 103 of them were enrolled for the study concerning the VitD evaluation in serum and follicular fluid at the time of the egg retrieval. This took place both in 34 pregnant patients (Group 1) and 69 non-pregnant ones (Group 2). Furthermore, the collection of these data gave us the opportunity to assess a possible correlation between the VitD levels and the achievement of pregnancy in the performed IVF cycles. RESULTS: The studied group included 103 eligible women. The average age for Group 1 was 33.12 ± 3.72 yrs whereas 33.72+3.99 yrs (p=0.467) for Group 2. The main differences were observed concerning follicle numbers of 17-21 mm (p=0.0043), the number of retrieved oocytes (p=0.0207), as well as the number of mature oocytes (p=0.0233) among the different groups. Different reference ranges, established according to the pregnancy outcomes, revealed that pregnant women with >36 yrs showed significantly higher levels of VitD. CONCLUSIONS: Increased serum and FF-VitD levels in women undergoing IVF with age ≥36 yrs, were significantly associated with a favorable outcome to achieve and carry on with the pregnancy. [ABSTRACT FROM AUTHOR]

Published
2021

48. Ethical Design in the Internet of Things

Author

Tallacchini, Mariachiara, Baldini, G, Botterman, M, Neisse, R, Tallacchini M (ORCID:0000-0003-3730-3673), Tallacchini, Mariachiara, Baldini, G, Botterman, M, Neisse, R, and Tallacchini M (ORCID:0000-0003-3730-3673)

Abstract

Even though public awareness about privacy risks in the Internet is increasing, in the evolution of the Internet to the Internet of Things (IoT) these risks are likely to become more relevant due to the large amount of data collected and processed by the ‘‘Things’’. The business drivers for exploring ways to monetize such data are one of the challenges identified in this paper for the protection of Privacy in the IoT. Beyond the protection of privacy, this paper highlights the need for new approaches, which grant a more active role to the users of the IoT and which address other potential issues such as the Digital Divide or safety risks. A key facet in ethical design is the transparency of the technology and services in how that technology handles data, as well as providing choice for the user. This paper presents a new approach for users’ interaction with the IoT, which is based on the concept of Ethical Design implemented through a policy-based framework. In the proposed framework, users are provided with wider controls over personal data or the IoT services by selecting specific sets of policies, which can be tailored according to users’ capabilities and to the contexts where they operate. The potential deployment of the framework in a typical IoT context is described with the identification of the main stakeholders and the processes that should be put in place.

Published
2018

50. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018

Author

Gustafsson, U. O., primary, Scott, M. J., additional, Hubner, M., additional, Nygren, J., additional, Demartines, N., additional, Francis, N., additional, Rockall, T. A., additional, Young-Fadok, T. M., additional, Hill, A. G., additional, Soop, M., additional, de Boer, H. D., additional, Urman, R. D., additional, Chang, G. J., additional, Fichera, A., additional, Kessler, H., additional, Grass, F., additional, Whang, E. E., additional, Fawcett, W. J., additional, Carli, F., additional, Lobo, D. N., additional, Rollins, K. E., additional, Balfour, A., additional, Baldini, G., additional, Riedel, B., additional, and Ljungqvist, O., additional

Published
2018
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