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268 results on '"Baldan N"'

8. Retrospective multicenter study of post-operative stenosis after stapled colorectal anastomosis

Author

Sartori A, De Luca M, Fiscon V, Frego M, Vigna S, Mazzeo A, Coco D, Agresta F, Finotti E, Antoniutti M, Carnio S, Elio A, Brunelli M, Ruffo G, Bertocchi E, Parini D, Losacco L, Poli F, Santoro G, Massani M, Ruffolo C, Cian E, Zanatta L, Genna M, Ballarin A, Rebonato M, Fontana M, Moretto G, Impellizzeri H, Merenda R, Margani G, Merigliano S, Baldan N, Ubiali P, Braini A, Balani A, Kosuta M, Infantino A, Giacomel G, Armatura G, Patauner S, de Manzini N, Palmisano S, Sorrentino M, Brizzolari M, Belluco C, Olivieri M, Lauro E, Scudo G, Valduga P, Brolese A, Pignata G, Andreucetti J, Caruso A, Zappalà F, Portale G ., Sartori, A, De Luca, M, Fiscon, V, Frego, M, Vigna, S, Mazzeo, A, Coco, D, Agresta, F, Finotti, E, Antoniutti, M, Carnio, S, Elio, A, Brunelli, M, Ruffo, G, Bertocchi, E, Parini, D, Losacco, L, Poli, F, Santoro, G, Massani, M, Ruffolo, C, Cian, E, Zanatta, L, Genna, M, Ballarin, A, Rebonato, M, Fontana, M, Moretto, G, Impellizzeri, H, Merenda, R, Margani, G, Merigliano, S, Baldan, N, Ubiali, P, Braini, A, Balani, A, Kosuta, M, Infantino, A, Giacomel, G, Armatura, G, Patauner, S, de Manzini, N, Palmisano, S, Sorrentino, M, Brizzolari, M, Belluco, C, Olivieri, M, Lauro, E, Scudo, G, Valduga, P, Brolese, A, Pignata, G, Andreucetti, J, Caruso, A, Zappalà, F, and Portale G, .

Subjects
Male, medicine.medical_specialty, Colorectal anastomosis, Constriction, Pathologic, Anastomosis, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Risk Factors, Surgical Stapling, Prevalence, medicine, Humans, Colorectal anastomosi, Retrospective Studies, Stenosis, business.industry, Stapled anastomosis, Anastomosis, Surgical, Retrospective cohort study, Endoscopic dilatation, medicine.disease, Colorectal surgery, Surgery, Italy, Multicenter study, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Colorectal Neoplasms, business, Complication, Stapled anastomosi
Abstract

Anastomotic stenosis after colorectal surgery is usually considered low-rate complication and often is under-reported in most studies. Few data are available on management strategies. The aim of the study was to assess the prevalence of stenosis after stapled colorectal anastomosis, performed either in elective or emergent setting, for benign or malignant disease, and to evaluate treatment profiles. This retrospective study was a survey conducted in a large Italian North-Eastern area including three regions (Triveneto), over a 12-month period (January–December 2015). Patients’ characteristics and surgical technique details were recorded, along with data on the prevalence of stenosis and its treatment. Patients with mid or low rectal resection and/or neoadjuvant chemo-radio therapy and/or diverting stoma were excluded. The study was promoted by the Italian Association of Hospital Surgeons (ACOI) and the Society of Surgeons of the Triveneto Region. Twenty-eight surgical units were enrolled in the survey, accounting for over 1400 patients studied. Fifty percent of the units performed laparoscopically > 70% of the colorectal resections and 7.5% of the procedures were emergent. Less than 60% of the units planned regular endoscopic follow-up after colorectal resection. Anastomotic stricture was recorded in 2% of the patients; 88% of the stenoses were diagnosed within 6 months from surgery. Only one anastomotic stricture required re-do surgery. The CANSAS study confirms that colorectal anastomotic stenosis is low-rate—but still present—complication. Treatment strategies vary according to surgeons’ and endoscopists’ preferences. Commonly endoscopic dilatation is preferred, but re-do surgery is required in some cases.

Published
2019

9. Preliminary study in a life supporting pig to primate xenotransplantation model using GAL KO pigs transgenic for human CD39, CD55, CD59 and fucosyltransferase: LB IXA O-4

Author

Cozzi, E., Simioni, P., Nottle, M. B., Vadori, M., Benedictis, GM De, Baldan, N, Boldrin, M., Robson, S. C., Besenzon, F., Cavicchioli, L., Calabrese, F., Brunetti, D., Gavasso, S., Ekser, B., Radu, C., Seveso, M., Dedja, A., Fante, F., Salvaris, E., Tisato, V., Carraro, P., Galli, C., Soulillou, J. P., Blancho, G., dʼApice, A. J., Ancona, E., and Cowan, P. J.

Published
2009

21. Lessons learned from 227 biological meshes used for the surgical treatment of ventral abdominal defects.

Author

Baldan, N., Munegato, G., Di Leo, A., Lauro, E., Morpurgo, E., Pianigiani, S., Briscolini, D., Ferrara, R., Fiscon, V., Brolese, A., De Manzoni, G., Baldazzi, G., Snidero, D., Merigliano, S., Ricci, F., Laterza, E., Merenda, R., Gianesini, R., and NEI-Meshing Collaborative

Subjects
*VENTRAL hernia, *SURGICAL meshes, *SURGICAL complications, *SURGICAL site, *ABDOMINAL wall, *CORONARY disease
Abstract

Purpose: The advantages of biological meshes for ventral hernia repair are still under debate. Given the high financial cost, the proper indications for biological meshes should be clarified to restrict their use to properly selected patients.Methods: A retrospective database was instituted to register all cases of abdominal wall defect treated with biological meshes from 1/2010 to 3/2016.Results: A total of 227 patients (mean age: 64 years) whose ventral abdominal defects were reconstructed with a biological mesh were included in the study. Patients were divided according to the 2010 four-level surgical-site complication risk grading system proposed by the Ventral Hernia Working Group (VHWG): Grade 1 (G1, 12 cases), Grade 2 (G2, 68 cases), Grade 3 (G3, 112 cases), and Grade 4 (G4, 35 cases). The surgical site complication rate was higher in patients with one or more risk factors (33.6% vs 19% in patients with no risk factors) (P = 0.68). Statistically significant risk factors associated with the onset of one or more postoperative surgical site complications included: diabetes, coronary artery disease, immunosuppression, and obesity. Recurrence was more common in patients with surgical site complications and mainly associated with infection (38.9%) and wound necrosis (44.4%), and in cases of inlay positioning of the mesh (36%).Conclusions: Due to their high costs, biological mesh should not be used in G1 patients. In infected fields (G4), they should only be used if no other surgical solution is feasible. There is a clear need to prospectively evaluate the performance of biological meshes. [ABSTRACT FROM AUTHOR]

Published
2020
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22. Carbon monoxide segnificantly reduces the apoptotic events associated with ischemia-reperfusion injury: observations in a renal pig-to-primate model

Author

Cozzi, E, Seveso, M, Calabrese, F, De Benedictis, G, Baldan, N, Boldrin, M, Castagnaro, M, Ravarotto, L, Carraro, P, Busetto, R, Otterbein, LE, Bernardini, D, Thiene, G, Bach, FH, Ancona, E., LAVITRANO, MARIALUISA, Cozzi, E, Seveso, M, Calabrese, F, De Benedictis, G, Baldan, N, Boldrin, M, Castagnaro, M, Ravarotto, L, Carraro, P, Busetto, R, Otterbein, L, Lavitrano, M, Bernardini, D, Thiene, G, Bach, F, and Ancona, E

Subjects
xenotransplantation, ischemia-reperfusion injury, transplantation
Published
2004

28. Preliminary study in a life supporting pig to primate xenotransplantation model using GAL KO pigs transgenic for human CD39, CD55, CD59 and fucosyltransferase

Author

Cozzi, E, Simioni, Paolo, Nottle, Mb, Vadori, M, DE BENEDICTIS, GIULIA MARIA, Baldan, N, Boldrin, M, Robson, Sc, Besenzon, F, Cavicchioli, Laura, Calabrese, Fiorella, Brunetti, D, Gavasso, S, Ekser, B, Radu, C, Seveso, M, Dedja, Arben, Fante, F, Salvaris, E, Tisato, V, Carraro, P, Galli, C, Soulillou, Jp, Blancho, G, D'Apice, Aj, Ancona, Ermanno, and Cowan, Pj

Published
2009

36. Topical photodynamic therapy of actinic keratosis in renal transplant recipients

Author

Piaserico, Stefano, Fortina, Ab, Rigotti, Paolo, Rossi, B, Baldan, N, Alaibac, MAURO SALVATORE ALESSANDRO, Marchini, F., and BELLONI FORTINA, Anna

Subjects
medicine.medical_specialty, Administration, Topical, medicine.medical_treatment, Population, Photodynamic therapy, Cryotherapy, Imiquimod, Organ transplantation, Postoperative Complications, medicine, Humans, Photosensitivity Disorders, education, Aged, Retrospective Studies, Transplantation, education.field_of_study, Photosensitizing Agents, business.industry, Actinic keratosis, Aminolevulinic Acid, Keratosis, Middle Aged, medicine.disease, Kidney Transplantation, Dermatology, Surgery, Solar keratosis, Photochemotherapy, business, Follow-Up Studies, medicine.drug
Abstract

Organ transplant recipients (OTRs) show an increased risk of precancerous (mostly actinic keratosis [AK]) and cancerous (mostly squamous cell carcinomas [SCC] and basal cell carcinomas [BCC]) cutaneous lesions. Their frequency increases with time after transplantation. AKs seem to progress more often and faster to invasive SCC in OTRs compared with the general population. The steady increase of risk of cutaneous premalignancies and malignancies with time after transplantation is an alarming figure because the number of organ allograft recipients who live for many years after transplantion is rapidly growing. This points out the need to devote more resources to skin cancer prevention, detection, and management. Various therapies, including cryotherapy, topical 5-fluorouracil, imiquimod, topical diclofenac, curettage, electrosurgery, carbon dioxide laser, and surgical excision, are available for AKs. However, most of these are limited by frequent relapses and the presence of multiple lesions over a wide area. Topical photodynamic therapy (PDT) represents an innovative therapeutic approach for nonsurgical treatment of cutaneous precancerous lesions and skin cancers. In this study we confirmed the usefulness of PDT in the treatment of AKs in OTRs, even in lesions relapsing or unresponsive to conventional treatment. We showed a complete response rate of 71%, after 2 treatments sessions that were 2 weeks apart. The response rate of scalp/facial lesions (72%) was higher compared with acral lesions (40%). Topical PDT could represent a useful therapeutic alternative for AKs in OTRs because large lesions can be treated with excellent cosmetic outcome.

Published
2007

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