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37 results on '"Balasubramanian, Sandhya"'

1. Author Correction: Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia

Author

Al-Sawaf, Othman, Zhang, Can, Jin, Hyun Yong, Robrecht, Sandra, Choi, Yoonha, Balasubramanian, Sandhya, Kotak, Alex, Chang, Yi Meng, Fink, Anna Maria, Tausch, Eugen, Schneider, Christof, Ritgen, Matthias, Kreuzer, Karl-Anton, Chyla, Brenda, Paulson, Joseph N., Pallasch, Christian P., Frenzel, Lukas P., Peifer, Martin, Eichhorst, Barbara, Stilgenbauer, Stephan, Jiang, Yanwen, Hallek, Michael, and Fischer, Kirsten

Published
2023
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2. Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia

Author

Al-Sawaf, Othman, Zhang, Can, Jin, Hyun Yong, Robrecht, Sandra, Choi, Yoonha, Balasubramanian, Sandhya, Kotak, Alex, Chang, Yi Meng, Fink, Anna Maria, Tausch, Eugen, Schneider, Christof, Ritgen, Matthias, Kreuzer, Karl-Anton, Chyla, Brenda, Paulson, Joseph N., Pallasch, Christian P., Frenzel, Lukas P., Peifer, Martin, Eichhorst, Barbara, Stilgenbauer, Stephan, Jiang, Yanwen, Hallek, Michael, and Fischer, Kirsten

Published
2023
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3. P1244: AN AUTOMATED QUANTIFICATION ALGORITHM FOR EVALUATING TOTAL METABOLIC TUMOR VOLUME IN PATIENTS WITH FDG-AVID LYMPHOMAS USING A DEEP LEARNING MODEL

Author

Xu, Tao, primary, Jemaa, Skander, additional, Kumar, Manas, additional, Balasubramanian, Sandhya, additional, Shamas-Din, Aisha, additional, Lyalina, Svetlana, additional, Ounadjela, Souhila, additional, Malik, Bilal, additional, Lee, Joe, additional, Figueroa Morales, Salvador, additional, Nielsen, Tina, additional, Ad Carano, Rick, additional, Kostakoglu, Lale, additional, and Capra, William, additional

Published
2023
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5. High-Throughput Translational Medicine: Challenges and Solutions

Author

Sulakhe, Dinanath, Balasubramanian, Sandhya, Xie, Bingqing, Berrocal, Eduardo, Feng, Bo, Taylor, Andrew, Chitturi, Bhadrachalam, Dave, Utpal, Agam, Gady, Xu, Jinbo, Börnigen, Daniela, Dubchak, Inna, Gilliam, T. Conrad, Maltsev, Natalia, Cohen, Irun R., Series editor, Lajtha, Abel, Series editor, Paoletti, Rodolfo, Series editor, Lambris, John D., Series editor, Maltsev, Natalia, editor, Rzhetsky, Andrey, editor, and Gilliam, T. Conrad, editor

Published
2014
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7. Outcomes by BCL2 and MYC expression and rearrangements in untreated diffuse large B-cell lymphoma (DLBCL) from the POLARIX trial.

Author

Morschhauser, Franck, primary, Jiang, Yanwen, additional, Jardin, Fabrice, additional, Herrera, Alex Francisco, additional, Sehn, Laurie Helen, additional, Herbaux, Charles, additional, Flowers, Christopher, additional, Phillips, Tycel Jovelle, additional, López Guillermo, Armando, additional, Magid Diefenbach, Catherine S., additional, Gregory, Gareth, additional, Kim, Austin Injae, additional, Barbui, Anna Maria, additional, Balasubramanian, Sandhya, additional, Harris, Will, additional, Hirata, Jamie, additional, Paulson, Joseph N., additional, Lee, Calvin, additional, and Lenz, Georg, additional

Published
2022
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8. Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region

Author

Balasubramanian, Sandhya, primary, Andreani, Matteo, primary, Andrade, Júlia Goncalves, additional, Saha, Tannishtha, additional, Sundaravinayagam, Devakumar, additional, Garzón, Javier, additional, Zhang, Wenzhu, additional, Popp, Oliver, additional, Hiraga, Shin-ichiro, additional, Rahjouei, Ali, additional, Rosen, Daniel B, additional, Mertins, Philipp, additional, Chait, Brian T, additional, Donaldson, Anne D, additional, and Di Virgilio, Michela, additional

Published
2022
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9. Author response: Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region

Author

Balasubramanian, Sandhya, primary, Andreani, Matteo, primary, Andrade, Júlia Goncalves, additional, Saha, Tannishtha, additional, Sundaravinayagam, Devakumar, additional, Garzón, Javier, additional, Zhang, Wenzhu, additional, Popp, Oliver, additional, Hiraga, Shin-ichiro, additional, Rahjouei, Ali, additional, Rosen, Daniel B, additional, Mertins, Philipp, additional, Chait, Brian T, additional, Donaldson, Anne D, additional, and Di Virgilio, Michela, additional

Published
2022
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10. Plasma Circulating Tumor DNA (ctDNA) as an Alternative to Tissue DNA for Genotyping of DLBCL: Results from the POLARIX Study

Author

Jardin, Fabrice, Raghavan, Vibha, Tracy, Samuel, Balasubramanian, Sandhya, Sehn, Laurie H., Flowers, Christopher R., Morschhauser, Franck, Herrera, Alex F., Trněný, Marek, Sharman, Jeff P., Salles, Gilles, Tilly, Hervé, Friedberg, Jonathan W., Harris, Will, Hirata, Jamie H., Lee, Calvin, Jiang, Yanwen, and Lenz, Georg

Published
2023
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13. PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

Author

Delgado-Benito, Verónica, Berruezo-Llacuna, Maria, Altwasser, Robert, Winkler, Wiebke, Sundaravinayagam, Devakumar, Balasubramanian, Sandhya, Caganova, Marieta, Graf, Robin, Rahjouei, Ali, Henke, Marie-Thérèse, Driesner, Madlen, Keller, Lisa, Prigione, Alessandro, Janz, Martin, Akalin, Altuna, and Di Virgilio, Michela

Subjects
Cancer Research, Cardiovascular and Metabolic Diseases, Technology Platforms, Function and Dysfunction of the Nervous System
Abstract

The establishment of protective humoral immunity is dependent on the ability of mature B cells to undergo antibody gene diversification while adjusting to the physiological stressors induced by activation with the antigen. Mature B cells diversify their antibody genes by class switch recombination (CSR) and somatic hypermutation (SHM), which are both dependent on efficient induction of activation-induced cytidine deaminase (AID). Here, we identified PDGFA-associated protein 1 (Pdap1) as an essential regulator of cellular homeostasis in mature B cells. Pdap1 deficiency leads to sustained expression of the integrated stress response (ISR) effector activating transcription factor 4 (Atf4) and induction of the ISR transcriptional program, increased cell death, and defective AID expression. As a consequence, loss of Pdap1 reduces germinal center B cell formation and impairs CSR and SHM. Thus, Pdap1 protects mature B cells against chronic ISR activation and ensures efficient antibody diversification by promoting their survival and optimal function.

Published
2020

14. High-Throughput Translational Medicine: Challenges and Solutions

Author

Sulakhe, Dinanath, primary, Balasubramanian, Sandhya, additional, Xie, Bingqing, additional, Berrocal, Eduardo, additional, Feng, Bo, additional, Taylor, Andrew, additional, Chitturi, Bhadrachalam, additional, Dave, Utpal, additional, Agam, Gady, additional, Xu, Jinbo, additional, Börnigen, Daniela, additional, Dubchak, Inna, additional, Gilliam, T. Conrad, additional, and Maltsev, Natalia, additional

Published
2013
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19. PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

Author

Delgado-Benito, Verónica, primary, Berruezo-Llacuna, Maria, additional, Altwasser, Robert, additional, Winkler, Wiebke, additional, Sundaravinayagam, Devakumar, additional, Balasubramanian, Sandhya, additional, Caganova, Marieta, additional, Graf, Robin, additional, Rahjouei, Ali, additional, Henke, Marie-Thérèse, additional, Driesner, Madlen, additional, Keller, Lisa, additional, Prigione, Alessandro, additional, Janz, Martin, additional, Akalin, Altuna, additional, and Di Virgilio, Michela, additional

Published
2020
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20. Pdap1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

Author

Delgado-Benito, Verónica, primary, Berruezo-Llacuna, Maria, additional, Altwasser, Robert, additional, Winkler, Wiebke, additional, Balasubramanian, Sandhya, additional, Sundaravinayagam, Devakumar, additional, Graf, Robin, additional, Rahjouei, Ali, additional, Driesner, Madlen, additional, Keller, Lisa, additional, Janz, Martin, additional, Akalin, Altuna, additional, and Virgilio, Michela Di, additional

Published
2020
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22. Recapitulation of Prognostic Mutational Subtyping Utilizing F1H in GOYA and CAVALLI and the Potential to Highlight Benefit of Targeted Therapy in De Novo DLBCL

Author

Kim, Eugene C, primary, Fan, Jinzhen, additional, Bolen, Christopher R, additional, Bazeos, Alexandra, additional, Jiang, Yanwen, additional, Balasubramanian, Sandhya, additional, Balakrishnan, Rama, additional, Knapp, Andrea, additional, Humphrey, Kathryn, additional, Nielsen, Tina G, additional, Venstrom, Jeffrey M., additional, Hernandez, Genevive, additional, and Paulson, Joseph N, additional

Published
2019
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24. Lynx: a knowledge base and an analytical workbench for integrative medicine

Author

Sulakhe, Dinanath, primary, Xie, Bingqing, additional, Taylor, Andrew, additional, D'Souza, Mark, additional, Balasubramanian, Sandhya, additional, Hashemifar, Somaye, additional, White, Steven, additional, Dave, Utpal J., additional, Agam, Gady, additional, Xu, Jinbo, additional, Wang, Sheng, additional, Gilliam, T. Conrad, additional, and Maltsev, Natalia, additional

Published
2015
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27. Circulating tumor DNA (ctDNA) status and clinical outcomes in patients (pts) with previously untreated diffuse large B-cell lymphoma (DLBCL) in the POLARIX study.

Author

Herrera, Alex Francisco, Tracy, Samuel, Sehn, Laurie Helen, Jardin, Fabrice, Lenz, Georg, Trneny, Marek, Salles, Gilles A., Flowers, Christopher, Tilly, Herve, Sharman, Jeff Porter, Friedberg, Jonathan W., Balasubramanian, Sandhya, Raghavan, Vibha, Hirata, Jamie H., Lee, Calvin, Jiang, Yanwen, and Morschhauser, Franck

Published
2023
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29. An Integrative Computational Approach for Prioritization of Genomic Variants

Author

Dubchak, Inna, primary, Balasubramanian, Sandhya, additional, Wang, Sheng, additional, Meyden, Cem, additional, Sulakhe, Dinanath, additional, Poliakov, Alexander, additional, Börnigen, Daniela, additional, Xie, Bingqing, additional, Taylor, Andrew, additional, Ma, Jianzhu, additional, Paciorkowski, Alex R., additional, Mirzaa, Ghayda M., additional, Dave, Paul, additional, Agam, Gady, additional, Xu, Jinbo, additional, Al-Gazali, Lihadh, additional, Mason, Christopher E., additional, Ross, M. Elizabeth, additional, Maltsev, Natalia, additional, and Gilliam, T. Conrad, additional

Published
2014
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30. Lynx: a database and knowledge extraction engine for integrative medicine

Author

Sulakhe, Dinanath, primary, Balasubramanian, Sandhya, additional, Xie, Bingqing, additional, Feng, Bo, additional, Taylor, Andrew, additional, Wang, Sheng, additional, Berrocal, Eduardo, additional, Dave, Utpal, additional, Xu, Jinbo, additional, Börnigen, Daniela, additional, Gilliam, T. Conrad, additional, and Maltsev, Natalia, additional

Published
2013
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32. Copy number variants and infantile spasms: evidence for abnormalities in ventral forebrain development and pathways of synaptic function

Author

Paciorkowski, Alex R, primary, Thio, Liu Lin, additional, Rosenfeld, Jill A, additional, Gajecka, Marzena, additional, Gurnett, Christina A, additional, Kulkarni, Shashikant, additional, Chung, Wendy K, additional, Marsh, Eric D, additional, Gentile, Mattia, additional, Reggin, James D, additional, Wheless, James W, additional, Balasubramanian, Sandhya, additional, Kumar, Ravinesh, additional, Christian, Susan L, additional, Marini, Carla, additional, Guerrini, Renzo, additional, Maltsev, Natalia, additional, Shaffer, Lisa G, additional, and Dobyns, William B, additional

Published
2011
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36. Impact of Entrepreneurial Orientation on University Performance and Regional Economic Development.

Author

Balasubramanian, Sandhya, Yi Yang, and Tello, Steven

Abstract

Entrepreneurial orientation (EO) has been examined immensely through a growing stream of research in both entrepreneurship and strategic management literature. As a firm-level attribute, the beneficial relationship to firm performance has been established in the corporate sector leaving EO's implications in other sectors including university settings a rather underexplored area. Further, measurement of EO has been dominated by use of scales of initially proposed by Miller, warranting need for alternative method development. Our study adds to the body of literature that seeks to understand the dimensionality of EO and in contexts other than firms. We employ the use of content analysis of university president letters to measure university EO and establish its relationship to both commercialization of intellectual property and regional business development outcomes. The findings have significant managerial implications for higher education administrators as institutional adaptiveness, capacity of universities to generate new knowledge and facilitate spillovers that spur regional economic growth are true reflections of university entrepreneurialism. [ABSTRACT FROM AUTHOR]

Published
2015
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