1. Exposure to heavy metals in utero and autism spectrum disorder at age 3: a meta-analysis of two longitudinal cohorts of siblings of children with autism
- Author
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Dou, John F, Schmidt, Rebecca J, Volk, Heather E, Nitta, Manon M, Feinberg, Jason I, Newschaffer, Craig J, Croen, Lisa A, Hertz-Picciotto, Irva, Fallin, M Daniele, and Bakulski, Kelly M
- Subjects
Epidemiology ,Public Health ,Health Sciences ,Brain Disorders ,Prevention ,Autism ,Women's Health ,Mental Health ,Pregnancy ,Pediatric ,Intellectual and Developmental Disabilities (IDD) ,2.3 Psychological ,social and economic factors ,Reproductive health and childbirth ,Quality Education ,Humans ,Autism Spectrum Disorder ,Female ,Metals ,Heavy ,Prenatal Exposure Delayed Effects ,Siblings ,Child ,Preschool ,Longitudinal Studies ,Male ,Maternal Exposure ,Environmental Pollutants ,Cohort Studies ,Metals exposure ,Autism spectrum disorder ,Pregnancy cohort ,Cadmium ,ExWAS ,Public Health and Health Services ,Toxicology ,Public health - Abstract
BackgroundAutism spectrum disorder (ASD) is a prevalent and heterogeneous neurodevelopmental disorder. Risk is attributed to genetic and prenatal environmental factors, though the environmental agents are incompletely characterized.MethodsIn Early Autism Risk Longitudinal Investigation (EARLI) and Markers of Autism Risk in Babies Learning Early Signs (MARBLES), two pregnancy cohorts of siblings of children with ASD, urinary metals concentrations during two pregnancy time periods (
- Published
- 2024