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27 results on '"Bain, C. R."'

1. Postoperative systemic inflammation after major abdominal surgery: patient‐centred outcomes.

Author

Bain, C. R., Myles, P. S., Martin, C., Wallace, S., Shulman, M. A., Corcoran, T., Bellomo, R., Peyton, P., Story, D. A., Leslie, K., Forbes, A., Myles, Paul, Bellomo, Rinaldo, Corcoran, Tomas, Christophi, Chris, Forbes, Andrew, Peyton, Phil, Story, David, Leslie, Kate, and Serpell, Jonathan

Subjects
*ABDOMINAL surgery, *FLUID therapy, *INTENSIVE care units, *ACUTE kidney failure, *CLINICAL medicine, *INFLAMMATION
Abstract

Summary: Postoperative systemic inflammation is strongly associated with surgical outcomes, but its relationship with patient‐centred outcomes is largely unknown. Detection of excessive inflammation and patient and surgical factors associated with adverse patient‐centred outcomes should inform preventative treatment options to be evaluated in clinical trials and current clinical care. This retrospective cohort study analysed prospectively collected data from 3000 high‐risk, elective, major abdominal surgery patients in the restrictive vs. liberal fluid therapy for major abdominal surgery (RELIEF) trial from 47 centres in seven countries from May 2013 to September 2016. The co‐primary endpoints were persistent disability or death up to 90 days after surgery, and quality of recovery using a 15‐item quality of recovery score at days 3 and 30. Secondary endpoints included: 90‐day and 1‐year all‐cause mortality; septic complications; acute kidney injury; unplanned admission to intensive care/high dependency unit; and total intensive care unit and hospital stays. Patients were assigned into quartiles of maximum postoperative C‐reactive protein concentration up to day 3, after multiple imputations of missing values. The lowest (reference) group, quartile 1, C‐reactive protein ≤ 85 mg.l‐1, was compared with three inflammation groups: quartile 2 > 85 mg.l‐1 to 140 mg.l‐1; quartile 3 > 140 mg.l‐1 to 200 mg.l‐1; and quartile 4 > 200 mg.l‐1 to 587 mg.l‐1. Greater postoperative systemic inflammation had a higher adjusted risk ratio (95%CI) of persistent disability or death up to 90 days after surgery, quartile 4 vs. quartile 1 being 1.76 (1.31–2.36), p < 0.001. Increased inflammation was associated with increasing decline in risk‐adjusted estimated medians (95%CI) for quality of recovery, the quartile 4 to quartile 1 difference being ‐14.4 (‐17.38 to ‐10.71), p < 0.001 on day 3, and ‐5.94 (‐8.92 to ‐2.95), p < 0.001 on day 30. Marked postoperative systemic inflammation was associated with increased risk of complications, poor quality of recovery and persistent disability or death up to 90 days after surgery. [ABSTRACT FROM AUTHOR]

Published
2023
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3. Postoperative systemic inflammatory dysregulation and corticosteroids: a narrative review.

Author

Bain, C. R., Myles, P. S., Corcoran, T., and Dieleman, J. M.

Subjects
*CORTICOSTEROIDS, *CLINICAL trials, *DIETARY supplements, *NARRATIVES
Abstract

Summary: In some patients, the inflammatory‐immune response to surgical injury progresses to a harmful, dysregulated state. We posit that postoperative systemic inflammatory dysregulation forms part of a pathophysiological response to surgical injury that places patients at increased risk of complications and subsequently prolongs hospital stay. In this narrative review, we have outlined the evolution, measurement and prediction of postoperative systemic inflammatory dysregulation, distinguishing it from a healthy and self‐limiting host response. We reviewed the actions of glucocorticoids and the potential for heterogeneous responses to peri‐operative corticosteroid supplementation. We have then appraised the evidence highlighting the safety of corticosteroid supplementation, and the potential benefits of high/repeated doses to reduce the risks of major complications and death. Finally, we addressed how clinical trials in the future should target patients at higher risk of peri‐operative inflammatory complications, whereby corticosteroid regimes should be tailored to modify not only the a priori risk, but also further adjusted in response to markers of an evolving pathophysiological response. [ABSTRACT FROM AUTHOR]

Published
2023
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7. 19Ne(p,γ)20Na and 19Ne(d,n)20Na reactions and its astrophysical implications for the transition of the hot CNO cycle to the rp process

Author

Vancraeynest, G., Decrock, Patrick, Gaelens, Michel, Huyse, Mark, Van Duppen, Piet, Bain, C. R., Davinson, Thomas, Page, Robert, Shotter, Alan C., Woods, P.J., Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Coszach, R., Delbar, Th, Galster, Wilfried, Graulich, Jean Sébastien, Leleux, Pol, Liénard, Etienne, Lipnik, Peter, Michotte, C., Ninane, A., Vervier, Jean, Herndl, H., Oberhummer, Heinz, Sükösd, Cs, Wiescher, Michael, Vancraeynest, G., Decrock, Patrick, Gaelens, Michel, Huyse, Mark, Van Duppen, Piet, Bain, C. R., Davinson, Thomas, Page, Robert, Shotter, Alan C., Woods, P.J., Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Coszach, R., Delbar, Th, Galster, Wilfried, Graulich, Jean Sébastien, Leleux, Pol, Liénard, Etienne, Lipnik, Peter, Michotte, C., Ninane, A., Vervier, Jean, Herndl, H., Oberhummer, Heinz, Sükösd, Cs, and Wiescher, Michael

Abstract

The population of the 20Na resonances at 448, 661, 797, and 887 keV above the proton threshold has been studied in measurements of the 19Ne(p, γ)20Na reaction with radioactive 19Ne beams. The data have been analyzed fully in terms of resonance strengths, enabling a comparison with theoretical estimates and the extraction of upper and lower limits on the resonant part of the 19Ne(p, γ)20Na astrophysical reaction rate. The total cross section of the 19Ne(d,n)20Na reaction has been measured from 0.6 to 1.8 MeV (c.m.). On the basis of the results of a subsequent distorted-wave Born approximation analysis the direct component of the 19Ne(p, γ)20Na astrophysical reaction rate has been calculated in a potential model. The astrophysical implications of the resulting total reaction rate have been investigated: the conditions for the breakout from the hot CNO cycle into the rapid-proton capture process are determined by the preceding 15O(α, γ)19Ne reaction and the photodisintegration of the produced 20Na nuclei will not impede the breakout., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1998

8. The 19Ne(p,γ)20Na astrophysical reaction rate determined from measurements with a radioactive beam

Author

Vancraeynest, G., Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Th, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Graulich, Jean Sébastien, Huyse, Mark, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, C., Ninane, A., Page, Robert, Sellin, Paul, Shotter, Alan C., Sükösd, Cs, Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, Woods, P.J., Vancraeynest, G., Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Th, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Graulich, Jean Sébastien, Huyse, Mark, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, C., Ninane, A., Page, Robert, Sellin, Paul, Shotter, Alan C., Sükösd, Cs, Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, and Woods, P.J.

Abstract

The 19Ne(p,γ)20Na as well as the 19Ne(d,n)20Na reaction have been studied in inverse kinematics using 19Ne radioactive beams. Upper and lower limits for the 19Ne(p,γ)20Na astrophysical reaction rate have been deduced, for the first time on the basis of direct experimental data. It is concluded that the transition from the hot-CNO cycle to the rp-process in explosive hydrogen burning is most likely governed by the preceeding 15O(a,γ)19Ne reaction., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1997

9. New limits for the 19Ne(p,γ)20Na astrophysical reaction rate from direct measurements using radioactive beams

Author

Michotte, C., Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Th, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Graulich, Jean Sébastien, Huyse, Mark, Leleux, Pol, Liénard, Etienne, Lipnik, Peter, Ninane, A., Shotter, Alan C., Sükösd, Cs, Vancraeynest, G., Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, Woods, P.J., Michotte, C., Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Th, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Graulich, Jean Sébastien, Huyse, Mark, Leleux, Pol, Liénard, Etienne, Lipnik, Peter, Ninane, A., Shotter, Alan C., Sükösd, Cs, Vancraeynest, G., Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, and Woods, P.J.

Abstract

In explosive stellar hydrogen burning, the hot CNO cycles and the rp-process are mainly linked by the reaction sequence 15O(α, γ)19Ne(p,γ)20Na. Using intense 19Ne radioactive beams, both the 19Ne(p,γ) and the 19Ne(d,n) reaction have been studied. Upper and lower limits for the 19Ne(p,γ) reaction rate have been deduced, allowing to conclude that the 15O(α,γ) reaction is most likely the bottleneck reaction., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1996

10. A direct measurement of the 19Ne(p,γ)20Na reaction

Author

Page, Robert D., Vancraeynest, G., Shotter, Alan C., Huyse, Mark, Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Thierry, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, E., Lipnik, Peter, Michotte, C., Ninane, A., Sellin, Paul, Sükösd, Cs, Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, Woods, Philippe J., Page, Robert D., Vancraeynest, G., Shotter, Alan C., Huyse, Mark, Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Thierry, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, E., Lipnik, Peter, Michotte, C., Ninane, A., Sellin, Paul, Sükösd, Cs, Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, and Woods, Philippe J.

Abstract

The 19 Ne(p,γ); 20 Na reaction may be of considerable influence for the reaction flow between the CNO and NeNa mass region in high temperature hydrogen burning conditions. The proposed low energy resonance at 0.447 MeV has been measured in inverse kinematics with the Louvain‐la‐Neuve ;19 Ne beam, using novel activation techniques. An upper limit to the resonance strength has been determined and the implications for the spin assignment of the 2.646 MeV state in 20 Na as well as for the stellar reaction rate are discussed. © ;1995 American Institute of Physics., info:eu-repo/semantics/published

Published
1995

11. A direct measurement of the 18F(p,α)15 O reaction

Author

Coszach, R., Cogneau, Michel, Delbar, Th, Galster, Wilfried, Graulich, Jean Sébastien, Labar, Daniel, Leleux, Pierre, Loiselet, Marc, Michotte, C., Ryckewaert, Guido, Vervier, Jean, Bain, C. R., Davinson, Thomas, Irvine, R F, Neal, R., Shotter, A.S. A.S., Woods, Ph P.J., Binon, Freddy, Vanhorenbeeck, Jean, Decrock, Patrick, Gaelens, Michel, Goerres, J., Wiescher, Michael, Coszach, R., Cogneau, Michel, Delbar, Th, Galster, Wilfried, Graulich, Jean Sébastien, Labar, Daniel, Leleux, Pierre, Loiselet, Marc, Michotte, C., Ryckewaert, Guido, Vervier, Jean, Bain, C. R., Davinson, Thomas, Irvine, R F, Neal, R., Shotter, A.S. A.S., Woods, Ph P.J., Binon, Freddy, Vanhorenbeeck, Jean, Decrock, Patrick, Gaelens, Michel, Goerres, J., and Wiescher, Michael

Abstract

The cross section for the 18F(p,α) 15O reaction has been obtained in reverse kinematics (18F beam on CH2 target) between 550 and 740 keV above threshold, i.e. in a region of astrophysical interest. The reaction yield is dominated by a wide resonant state whose spin, parity, total width and partial widths were deduced from the analysis of the α-particle and elastic proton data., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1995

12. Nuclear reactions of astrophysical interest with radioactive beams

Author

Huyse, Mark, Bain, C. R., Binon, Freddy, Davinson, Thomas, Duhamel, Paul, Decrock, Patrick, Coszach, R., Delbar, Th, Gaelens, Michel, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Loiselet, Marc, Michotte, C., Page, R., Ryckewaert, Guido, Sellin, Paul, Shotter, Alan C., Sükösd, Cs, Vancraeynest, G., Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, Woods, P., Huyse, Mark, Bain, C. R., Binon, Freddy, Davinson, Thomas, Duhamel, Paul, Decrock, Patrick, Coszach, R., Delbar, Th, Gaelens, Michel, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Loiselet, Marc, Michotte, C., Page, R., Ryckewaert, Guido, Sellin, Paul, Shotter, Alan C., Sükösd, Cs, Vancraeynest, G., Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, and Woods, P.

Abstract

The ARENAS3 facility, coupling the two cyclotrons of Louvain-la-Neuve, is intensively been used over the past years for cross-section measurements of nuclear reactions of astrophysical interest. We will describe the characteristics of the available beams and the experiments going on using these beams. The 19Ne(p,γ)20Na reaction, of considerable importance for the reaction flow between the CNO and the NeNa mass region in high-temperature hydrogen burning conditions, will be discussed in particular. The proposed low-energy resonance at 0.447 MeV has been measured in inverse kinematics using novel activation techniques. An upper limit (90% C.L.) of 18 meV is obtained for the strength of this first particle-unbound state of 20Na together with preliminary values for the strength of the higher excited states. © 1995., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1995

13. First experimental eimit on the Ne19(p,γ)Na20 resonance strength, of astrophysical interest

Author

Page, Robert, Vancraeynest, G., Shotter, Alan C., Huyse, Mark, Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Th, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, C., Ninane, A., Sellin, Paul, Sükösd, Cs, Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, Woods, P.J., Page, Robert, Vancraeynest, G., Shotter, Alan C., Huyse, Mark, Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Decrock, Patrick, Delbar, Th, Duhamel, Paul, Gaelens, Michel, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, C., Ninane, A., Sellin, Paul, Sükösd, Cs, Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, and Woods, P.J.

Abstract

The 19Ne(p, γ)20Na reaction may influence considerably the reaction flow between the CNO and NeNa mass regions in high temperature hydrogen burning conditions. The 447 keV resonance has been studied by exploiting radioactive 19Ne beams with novel detection techniques to measure β+ -delayed α radioactivity of 20Na nuclei produced in reactions with polyethylene targets. A 90% C.L. upper limit of 18 meV for the resonance strength has been determined and implications for the spin assignment of the 2.646 MeV state in 20Na and the stellar reaction rate are discussed., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1994

14. Resonant scattering of isobaric 19Ne and 19F beams on an H target

Author

Coszach, R., Delbar, Thierry, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, Claude, Ninane, A., Vervier, Jean, Bain, C. R., Davinson, Thomas, Page, Robert D., Shotter, Alan C., Woods, Philippe J., Descouvemont, Pierre, Baye, Daniel Jean, Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Vincke, Marc, Decrock, Patrick, Huyse, Mark, Van Duppen, Piet, Vancraeynest, G., Barker, Frederick C., Coszach, R., Delbar, Thierry, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, Claude, Ninane, A., Vervier, Jean, Bain, C. R., Davinson, Thomas, Page, Robert D., Shotter, Alan C., Woods, Philippe J., Descouvemont, Pierre, Baye, Daniel Jean, Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Vincke, Marc, Decrock, Patrick, Huyse, Mark, Van Duppen, Piet, Vancraeynest, G., and Barker, Frederick C.

Abstract

Resonances in Na20 above the proton threshold have been studied by scattering radioactive Ne19 beams off thick polyethylene targets. The isobaric F19+p scattering was also examined. The analysis of the data under different theoretical approaches is discussed. The energy, total width, spin, and parity of two resonances in Na20 were assigned unambiguously. The results are compared to those obtained by indirect methods. © 1994 The American Physical Society., info:eu-repo/semantics/published

Published
1994

15. Resonant scattering of a 19Ne beams on a H-target

Author

Coszach, R., Delbar, Th, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, Claude, Vervier, Jean, Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Bain, C. R., Davinson, Thomas, Page, Robert D., Shotter, Alan C., Sellin, Paul, Woods, Philippe J., Decrock, Patrick, Huyse, Mark, Van Duppen, Piet, Roters, G., Trautvetter, H. P., Coszach, R., Delbar, Th, Galster, Wilfried, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, Claude, Vervier, Jean, Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Bain, C. R., Davinson, Thomas, Page, Robert D., Shotter, Alan C., Sellin, Paul, Woods, Philippe J., Decrock, Patrick, Huyse, Mark, Van Duppen, Piet, Roters, G., and Trautvetter, H. P.

Abstract

info:eu-repo/semantics/published

Published
1994

16. Measurements of the 19Ne(p,y) reaction rate using radioactive BEAMS

Author

Page, Robert D., Shotter, Alan C., Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Delbar, Th, Decrock, Patrick, Duhamel, Paul, Galster, Wilfried, Huyse, Mark, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, Claude, Ninane, A., Sellin, Paul, Vancraeynest, G., Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, Woods, Philippe J., Page, Robert D., Shotter, Alan C., Bain, C. R., Binon, Freddy, Coszach, R., Davinson, Thomas, Delbar, Th, Decrock, Patrick, Duhamel, Paul, Galster, Wilfried, Huyse, Mark, Leleux, Pol, Licot, I., Liénard, Etienne, Lipnik, Peter, Michotte, Claude, Ninane, A., Sellin, Paul, Vancraeynest, G., Van Duppen, Piet, Vanhorenbeeck, Jean, Vervier, Jean, Wiescher, Michael, and Woods, Philippe J.

Abstract

info:eu-repo/semantics/published

Published
1994

17. Nuclear astrophysics studies with radioactive Beams in Louvain-La-Neuve

Author

Michotte, Claude, Coszach, R., Delbar, Th, Galster, Wilfried, Leleux, Pol, Licot, I., Lienard, E., Lipnik, Peter, Ninane, A., Vervier, Jean, Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Decrock, Patrick, Gaelens, Michel, Huyse, Mark, Vancraeynest, G., Van Duppen, Piet, Bain, C. R., Davinson, Thomas, Page, Robert, Sellin, Paul, Shotter, Alan C., Woods, P., Michotte, Claude, Coszach, R., Delbar, Th, Galster, Wilfried, Leleux, Pol, Licot, I., Lienard, E., Lipnik, Peter, Ninane, A., Vervier, Jean, Binon, Freddy, Duhamel, Paul, Vanhorenbeeck, Jean, Decrock, Patrick, Gaelens, Michel, Huyse, Mark, Vancraeynest, G., Van Duppen, Piet, Bain, C. R., Davinson, Thomas, Page, Robert, Sellin, Paul, Shotter, Alan C., and Woods, P.

Abstract

info:eu-repo/semantics/published

Published
1994

18. 19Ne(p,γ)20Naand19Ne(d,n)20Nareactions and its astrophysical implications for the transition of the hot CNO cycle to therpprocess

Author

Vancraeynest, G., primary, Decrock, P., additional, Gaelens, M., additional, Huyse, M., additional, Van Duppen, P., additional, Bain, C. R., additional, Davinson, T., additional, Page, R. D., additional, Shotter, A. C., additional, Woods, P. J., additional, Binon, F., additional, Duhamel, P., additional, Vanhorenbeeck, J., additional, Coszach, R., additional, Delbar, Th., additional, Galster, W., additional, Graulich, J. S., additional, Leleux, P., additional, Liénard, E., additional, Lipnik, P., additional, Michotte, C., additional, Ninane, A., additional, Vervier, J., additional, Herndl, H., additional, Oberhummer, H., additional, Sükösd, Cs., additional, and Wiescher, M., additional

Published
1998
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19. A direct measurement of the 19Ne(p,γ)20Na reaction

Author

Page, R. D., primary, Vancraeynest, G., additional, Shotter, A. C., additional, Huyse, M., additional, Bain, C. R., additional, Binon, F., additional, Coszach, R., additional, Davinson, T., additional, Decrock, P., additional, Delbar, Th., additional, Duhamel, P., additional, Gaelens, M., additional, Galster, W., additional, Leleux, P., additional, Licot, I., additional, Liénard, E., additional, Lipnik, P., additional, Michotte, C., additional, Ninane, A., additional, Sellin, P. J., additional, Sükösd, Cs., additional, Duppen, P. Van, additional, Vanhorenbeeck, J., additional, Vervier, J., additional, Wiescher, M., additional, and Woods, P. J., additional

Published
1995
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20. First Experimental Limit on theNe19(p,γ)Na20Resonance Strength, of Astrophysical Interest

Author

Page, R. D., primary, Vancraeynest, G., additional, Shotter, A. C., additional, Huyse, M., additional, Bain, C. R., additional, Binon, F., additional, Coszach, R., additional, Davinson, T., additional, Decrock, P., additional, Delbar, Th., additional, Duhamel, P., additional, Gaelens, M., additional, Galster, W., additional, Leleux, P., additional, Licot, I., additional, Lienard, E., additional, Lipnik, P., additional, Michotte, C., additional, Ninane, A., additional, Sellin, P. J., additional, Sükösd, Cs., additional, Van Duppen, P., additional, Vanhorenbeeck, J., additional, Vervier, J., additional, Wiescher, M., additional, and Woods, P. J., additional

Published
1994
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21. Resonant scattering of isobaricNe19andF19beams on an H target

Author

Coszach, R., primary, Delbar, Th., additional, Galster, W., additional, Leleux, P., additional, Licot, I., additional, Liénard, E., additional, Lipnik, P., additional, Michotte, C., additional, Ninane, A., additional, Vervier, J., additional, Bain, C. R., additional, Davinson, T., additional, Page, R. D., additional, Shotter, A. C., additional, Woods, P. J., additional, Baye, D., additional, Binon, F., additional, Descouvemont, P., additional, Duhamel, P., additional, Vanhorenbeeck, J., additional, Vincke, M., additional, Decrock, P., additional, Huyse, M., additional, Van Duppen, P., additional, Vancraeynest, G., additional, and Barker, F. C., additional

Published
1994
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24. Redheads and anaesthesia--Reply.

Author

MYLES, P. S., BUCHANAN, F. F., and BAIN, C. R.

Subjects
LETTERS to the editor, HUMAN hair color, SURGERY
Abstract

A response by P. S. Myles et al. to a letter to the editor about their article "The Effect of Hair Colour on Anaesthetic Requirements and Recovery Time After Surgery" published in a 2012 issue is presented.

Published
2013

26. Data on the modulatory effects of a single bolus dexamethasone on the surface marker expression of various leucocyte subsets.

Author

Draxler DF, Bain CR, Taylor R, Wallace S, Gouldthorpe O, Corcoran TB, Myles PS, Bozaoglu K, and Medcalf RL

Abstract

Dexamethasone is frequently administered to surgical patients for anti-emetic prophylaxis. We have examined the immunomodulatory effects of a single bolus of dexamethasone on circulating peripheral blood mononuclear cells (PBMCs) in the same 10 healthy male volunteers, previously used in our investigation on early in vivo effects of a single anti-emetic dose of dexamethasone on innate immune cell gene expression and activation [1]. Blood samples were drawn at baseline, 2 h, 4 h and 24 h. Immune cell phenotypes were examined with flow cytometry. In this data article the expression strength of markers involved in immune activation and immunosuppression as well as maturation, migration, cell death and responsiveness to signalling on monocyte and cDC subsets, as well as NK cells, CD4+ and CD8+ T cells and regulatory T cells (Treg) are presented. These data improve our understanding of the immunomodulatory effects of the glucocorticoid dexamethasone in-vivo , which may be important for the optimisation of treatment regimens as well as the evaluation of new indications for glucocorticoid treatment., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships which have, or could be perceived to have, influenced the work reported in this article., (© 2020 The Authors.)

Published
2020
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