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Your search keyword '"Baikova, Irina P."' showing total 8 results
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8. Synthesis and Сytotoxicity of A-Azepanobetulinic Acid N-Methyl-Piperazinylamide

Author

Giniyatullina, Gulnara V., Kazakova, Oxana B., Baikova, Irina P., Yamansarov, Emil Yu., Osterman, Ilya A., Komarova, Ekaterina S., Skvortsov, Dmitry A., Saltikova, Irina V., Majouga, Alexander G., and Ivanenkov, Yan A.

Abstract

The synthesis of A-azepanobetulinic acid N-methylpiperazinylamide was performed through a series of transformations (oximation, Beckmann rearrangement, reduction) of previously synthesized betulonic acid N-methylpiperazinylamide. In vitro cytotoxic activity was detected for the obtained compound against a number of cancer cell lines, and its potential was revealed as an antibacterial agent.

Published
2019
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