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2 results on '"Bai, P. (Peter)"'

1. Successful Applications of Generic Atmospheric Correction Online Service for InSAR (GACOS) to the Reduction of Atmospheric Effects on InSAR Observations

Author

Chen YU,Zhenhong LI,Lin BAI,Jan-Peter MULLER,Jingfa ZHANG,Qiming ZENG

Subjects
insar, atmospheric correction, gacos, earthquake, volcano, landslide, city subsidence, Science, Geodesy, QB275-343
Abstract

The tremendous development of Synthetic Aperture Radar (SAR) missions in recent years facilitates the study of smaller amplitude ground deformation over greater spatial scales using longer time series. However, this poses greater challenges for correcting atmospheric effects due to the wider coverage of SAR imagery than ever. Previous attempts have used observations from Global Positioning System (GPS) and Numerical Weather Models (NWMs) to separate atmospheric delays, but they are limited by ①The availability (and distribution) of GPS stations; ②The low spatial resolution of NWM; And ③The difficulties in quantifying their performance. To overcome these limitations, we have developed the Generic Atmospheric Correction Online Service for InSAR (GACOS) which utilizes the high-resolution European Centre for Medium-Range Weather Forecasts (ECMWF) products using an Iterative Tropospheric Decomposition (ITD) model. This enables the reduction of the coupling effects of the troposphere turbulence and stratification and hence achieves equivalent performances over flat and mountainous terrains. GACOS comprises a range of notable features: ①Global coverage; ②All-weather, all-time usability; ③Available with a maximum of two-day latency; And ④Indicators available to assess the model’s performance and feasibility. In this paper, we demonstrate some successful applications of the GACOS online service to a variety of geophysical studies.

Published
2021
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2. ADP-ribosyltransferases, an update on function and nomenclature

Author

Lüscher, B. (Bernhard), Ahel, I. (Ivan), Altmeyer, M. (Matthias), Ashworth, A. (Alan), Bai, P. (Peter), Chang, P. (Paul), Cohen, M. (Michael), Corda, D. (Daniela), Dantzer, F. (Françoise), Daugherty, M. D. (Matthew D.), Dawson, T. M. (Ted M.), Dawson, V. L. (Valina L.), Deindl, S. (Sebastian), Fehr, A. R. (Anthony R.), Feijs, K. L. (Karla L. H.), Filippov, D. V. (Dmitri V.), Gagné, J.-P. (Jean-Philippe), Grimaldi, G. (Giovanna), Guettler, S. (Sebastian), Hoch, N. C. (Nicolas C.), Hottiger, M. O. (Michael O.), Korn, P. (Patricia), Kraus, W. L. (W. Lee), Ladurner, A. (Andreas), Lehtiö, L. (Lari), Leung, A. K. (Anthony K. L.), Lord, C. J. (Christopher J.), Mangerich, A. (Aswin), Matic, I. (Ivan), Matthews, J. (Jason), Moldovan, G.-L. (George-Lucian), Moss, J. (Joel), Natoli, G. (Gioacchino), Nielsen, M. L. (Michael L.), Niepel, M. (Mario), Nolte, F. (Friedrich), Pascal, J. (John), Paschal, B. M. (Bryce M.), Pawłowski, K. (Krzysztof), Poirier, G. G. (Guy G.), Smith, S. (Susan), Timinszky, G. (Gyula), Wang, Z.-Q. (Zhao-Qi), Yélamos, J. (José), Yu, X. (Xiaochun), Zaja, R. (Roko), Ziegler, M. (Mathias), Lüscher, B. (Bernhard), Ahel, I. (Ivan), Altmeyer, M. (Matthias), Ashworth, A. (Alan), Bai, P. (Peter), Chang, P. (Paul), Cohen, M. (Michael), Corda, D. (Daniela), Dantzer, F. (Françoise), Daugherty, M. D. (Matthew D.), Dawson, T. M. (Ted M.), Dawson, V. L. (Valina L.), Deindl, S. (Sebastian), Fehr, A. R. (Anthony R.), Feijs, K. L. (Karla L. H.), Filippov, D. V. (Dmitri V.), Gagné, J.-P. (Jean-Philippe), Grimaldi, G. (Giovanna), Guettler, S. (Sebastian), Hoch, N. C. (Nicolas C.), Hottiger, M. O. (Michael O.), Korn, P. (Patricia), Kraus, W. L. (W. Lee), Ladurner, A. (Andreas), Lehtiö, L. (Lari), Leung, A. K. (Anthony K. L.), Lord, C. J. (Christopher J.), Mangerich, A. (Aswin), Matic, I. (Ivan), Matthews, J. (Jason), Moldovan, G.-L. (George-Lucian), Moss, J. (Joel), Natoli, G. (Gioacchino), Nielsen, M. L. (Michael L.), Niepel, M. (Mario), Nolte, F. (Friedrich), Pascal, J. (John), Paschal, B. M. (Bryce M.), Pawłowski, K. (Krzysztof), Poirier, G. G. (Guy G.), Smith, S. (Susan), Timinszky, G. (Gyula), Wang, Z.-Q. (Zhao-Qi), Yélamos, J. (José), Yu, X. (Xiaochun), Zaja, R. (Roko), and Ziegler, M. (Mathias)

Abstract

ADP-ribosylation, a modification of proteins, nucleic acids, and metabolites, confers broad functions, including roles in stress responses elicited, for example, by DNA damage and viral infection and is involved in intra- and extracellular signaling, chromatin and transcriptional regulation, protein biosynthesis, and cell death. ADP-ribosylation is catalyzed by ADP-ribosyltransferases (ARTs), which transfer ADP-ribose from NAD⁺ onto substrates. The modification, which occurs as mono- or poly-ADP-ribosylation, is reversible due to the action of different ADP-ribosylhydrolases. Importantly, inhibitors of ARTs are approved or are being developed for clinical use. Moreover, ADP-ribosylhydrolases are being assessed as therapeutic targets, foremost as antiviral drugs and for oncological indications. Due to the development of novel reagents and major technological advances that allow the study of ADP-ribosylation in unprecedented detail, an increasing number of cellular processes and pathways are being identified that are regulated by ADP-ribosylation. In addition, characterization of biochemical and structural aspects of the ARTs and their catalytic activities have expanded our understanding of this protein family. This increased knowledge requires that a common nomenclature be used to describe the relevant enzymes. Therefore, in this viewpoint, we propose an updated and broadly supported nomenclature for mammalian ARTs that will facilitate future discussions when addressing the biochemistry and biology of ADP-ribosylation. This is combined with a brief description of the main functions of mammalian ARTs to illustrate the increasing diversity of mono- and poly-ADP-ribose mediated cellular processes.

Published
2021

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