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32 results on '"Bahnasy, Wafik Said"'

23. Additional file 1 of Gait and balance impairments in patients with subcortical vascular cognitive impairment

Author

Elhassanien, Mahmoud Ebrahim Mostafa, El-Heneedy, Yasser Abo Elfotoh, Ramadan, Kareem Mohammed, Kotait, Mona Ahmed, Elkholy, Amr, Elhamrawy, Mohammed Youssef, and Bahnasy, Wafik Said

Abstract

Additional file 1: Computerized dynamic posturography (CDP). Figure (*). The different conditions performed in the sensory organization test; (A) eyes open, surround and platform stable, (B) eyes closed, surround and platform stable, (C) eyes open, sway- referenced surround, (D) eyes open sway-referenced platform, (E) eyes closed, sway-referenced platform and (F) eyes open sway referenced surround and platform (Quoted from Massukawa Oda and Ganança, 2015).

Published
2021
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29. Sex Hormones and Alzheimer’s Disease

Author

Bahnasy, Wafik Said

Subjects
Medical / Endocrinology & Metabolism
Abstract

Alzheimer’s disease (AD) is the most common type of dementia and the most common neurodegenerative disorder of elderly. It is not an accelerated form of aging but it is characterized by distinct temporospatial brain pathological changes, including amyloid plaques accumulation, neurofibrillary tangles deposition, synaptic loss and neuronal death with gross brain atrophy. These changes result in persistent progressive memory and cognitive decline interfering with the usual daily activities. AD is a multifactorial disorder results from the interaction of genetic, epigenetic, environmental and lifestyle factors. Estrogen, progesterone and androgen effects are important building stones in AD pathogenesis, and their effect in brain modulation and development results in different gender susceptibility to the disease. These sex hormones whether gonadal or neurosteroids (synthesized locally in the brain) play important neuroprotective roles influencing the individual’s vulnerability to AD development, rate of mild cognitive impairment (MCI)/AD conversion and speed of AD progression. Despite the little therapeutic implications of hormonal replacement therapy in AD treatment, yet this topic still represents a challenging hopeful way to construct a strategy for the development of personalized, gender-specific AD management.

Published
2018

32. Early hematoma expansion in primary intracerebral hemorrhage: incidence and predictors.

Author

Elhady Helal, Hany Hamed Abd, Bahnasy, Wafik Said, Ghali, Azza Abbas, and Rabie, Mohammed Osman

Subjects
*HEMORRHAGE, *ARTERIAL pressure
Abstract

Background: Hematoma expansion (HE) is the leading cause of early neurological deterioration, poor functional outcome, and increased mortality in patients with spontaneous intracerebral hemorrhage (S-ICH). The study aimed to estimate the risks and predictors of early HE in patients with S-ICH and the effect of this HE on patient's survival and functional outcome. Methods: This study was carried out on 72 patients with S-ICH submitted to baseline non-contrast brain CT (NCCT) and CT angiography for determination of hematoma site, size, border irregularity, blend sign, and spot sign score (SSS). Rescan was done 48 h after stroke onset or on clinical deterioration to resize the HV and diagnose HE. Modified Rankin Scale (MRS) was done 3 months after stroke onset to assess the effect of HE on patients' physical dependence. Results: HE occurred in 28/72 (38.9%) of included patients. Risks of HE included old age, smoking, elevated baseline mean arterial blood pressure, and high admission modified National Institute of Health stroke scale. NCCT predictors of HE included large volume, irregular border, and presence of blend sign. The presence of spot sign in early CTA is more accurate than NCCT predictors with 54%, 91%, 79%, and 75% for sensitivity, specificity, positive predictive value, and negative predictive value, respectively. Conclusions: HE is a major cause of early clinical deterioration, increased mortality, and poor functional outcome. Early CTA for detection of spot sign is indicated in patients with large volume, irregular border, and/or blend sign in NCCT. [ABSTRACT FROM AUTHOR]

Published
2019
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