438 results on '"Bagley, Mark C."'
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2. Selective targeting of the αC and DFG-out pocket in p38 MAPK
3. Synthesis and Evaluation of a Silver Nanoparticle/Polyurethane Composite That Exhibits Antiviral Activity against SARS-CoV-2
4. Microwave-Assisted Multicomponent Reactionsfor the Synthesis of Heterocycles
5. A Convenient, Rapid, Conventional Heating Route to MIDA Boronates
6. Solvent‐Free Synthesis of Core‐Functionalised Naphthalene Diimides by Using a Vibratory Ball Mill: Suzuki, Sonogashira and Buchwald–Hartwig Reactions
7. Regiocontrolled synthesis of 3- and 5-aminopyrazoles, pyrazolo[3,4-d]pyrimidines, pyrazolo[3,4-b]pyridines and pyrazolo[3,4-b]quinolinones as MAPK inhibitors
8. New Approaches Towards Inhibitors of Folate-Dependent Enzymes: Rapid Synthesis of 5-Deazapterins From Uracil Derivatives
9. Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor
10. Synthesis and antimicrobial properties of some new thiazolyl coumarin derivatives
11. An efficient synthetic route to biologically relevant 2-phenylbenzothiazoles substituted on the benzothiazole ring
12. The effect of small-molecule inhibition of MAPKAPK2 on cell ageing phenotypes of fibroblasts from human Werner syndrome
13. Microwaves in Drug Discovery and Development: Recent Advances
14. Understanding ageing: biological and social perspectives
15. Microwave-assisted synthesis and antioxidant properties of hydrazinyl thiazolyl coumarin derivatives
16. Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors
17. Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells
18. Small Molecule Inhibition of p38 MAP Kinase Extends the Replicative Life Span of Human ATR-Seckel Syndrome Fibroblasts
19. Synthesis of methyl sulfomycinate, sulfomycinic amide and sulfomycinine, degradation products of the sulfomycin thiopeptide antibiotics
20. Gram-scale synthesis of the p38α MAPK-inhibitor VX-745 for preclinical studies into Werner syndrome
21. Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts
22. Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome
23. Microwave-assisted synthesis of a pyrazolyl ketone library for evaluation as p38 MAPK inhibitors in Werner syndrome cells
24. The Role of Cellular Senescence in Werner Syndrome: Toward Therapeutic Intervention in Human Premature Aging
25. Chemistry of α-(arylhydrazono)-β-ketoaldehydes: Preparation and Chemical Reactivities
26. Diterpenoids of terrestrial origin
27. Asymmetric synthesis of 1-azaspiro[4.5]decanes via intramolecular dipolar cycloaddition of nitrones containing the bornane-10,2-sultam chiral auxiliary
28. Microwave-assisted Ullmann C-S bond formation: synthesis of the P38[alpha] MAPK clinical candidate VX-745
29. A simple continuous flow microwave reactor
30. One-pot multistep Bohlmann-Rahtz heteroannulation reactions: Synthesis of dimethyl sulfomycinamate
31. Thiopeptide antibiotics
32. Recent Synthetic Approaches to N,N-Dimethyl-β-Ketoenamines
33. Recent developments in chemical reactivity of N,N-dimethylenamino ketones as synthons for various heterocycles
34. ChemInform Abstract: Microwave-Assisted Bohlmann-Rahtz Synthesis of Highly Substituted 2-Aminonicotinates.
35. Effect of Flecainide Derivatives on Sarcoplasmic Reticulum Ca2+ Release Confirms a Lack of Direct Action on the Cardiac Ryanodine Receptor
36. The effect of RO3201195 and a pyrazolyl ketone P38 MAPK inhibitor library on the proliferation of Werner syndrome cells
37. ChemInform Abstract: Microwave‐Assisted Synthesis of 3‐Aminobenzo[b]thiophene Scaffolds for the Preparation of Kinase Inhibitors.
38. Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors
39. Understanding ageing:biological and social perspectives
40. Understanding ageing
41. Microwave-assisted synthesis of MK2 inhibitors for targeting p38 MAPK signal transduction in Werner syndrome cells
42. ChemInform Abstract: Regiocontrolled Synthesis of 3- and 5-Aminopyrazoles, Pyrazolo[3,4-d]pyrimidines, Pyrazolo[3,4-b]pyridines and Pyrazolo[3,4-b]quinolinones as MAPK Inhibitors.
43. Chemistry of α-(arylhydrazono)-β-ketoaldehydes: Preparation and Chemical Reactivities
44. Rapid Ullmann-type synthesis of aryl sulfides using a copper(I) catalyst and ligand under microwave irradiation
45. One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor
46. Rapid Protium-Deuterium Exchange of 4-Aminopyridines in Neutral D2O under Microwave Irradiation.
47. Microwave-Assisted Bohlmann-Rahtz Synthesis of Highly Substituted 2-Aminonicotinates.
48. Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts.
49. Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38 MAPK inhibitor RO3201195 for study in Werner syndrome cells
50. Microwave-assisted Ullmann-Buchwald C-S bond formation using a copper(I) catalyst and trans-cyclohexane-1,2-diol as ligand
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