1. A randomized trial study on the effect of amniotic membrane graft on wound healing process after anal fistulotomy
- Author
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Ghahramani Leila, Pirayeh Saeideh, Khazraei Hajar, Bagher pour Ali, Hosseini Seyed Vahid, Noorafshan Ali, Safarpour Ali Reza, and Mousavi Laleh
- Subjects
Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Objective: Human amniotic membrane (HAM) used as a wound coverage for more than a century. The aim of this study is to evaluate the efficacy of amniotic membrane on wound healing and reduce post-operative complication. Study design: Randomized clinical trial study. Place and duration of study: Surgery Department, Shahid Faghihi Hospital, Shiraz, in the period of between Sep. 2014 and Nov. 2015. Methodology: 73 patients with anal fistula were divided into two groups. The patients suffered from simple perianal fistula (low type) without any past medical history. Fistulotomy were performed for all of them and in interventional group HAM were applied as biologic dressing. Their wound healing improvement was evaluated post-operative in two groups. Results: From 73 patients participated in the study, 36 patients were in control group and 37 patients were in intervention group. According to the analysis of images taken from the wound, the rate of wound healing was 67.39% in intervention group and 54.51% in control group (p
- Published
- 2017
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