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29 results on '"Bagaglia, Simone"'

6. Refractive surgical correction and treatment of keratoconus.

Author

D'Oria, Francesco, Bagaglia, Simone A., Alio del Barrio, Jorge L., Alessio, Giovanni, Alio, Jorge L., and Mazzotta, Cosimo

Subjects
*PHOTOREFRACTIVE keratectomy, *CORNEAL transplantation, *KERATOCONUS, *VISION disorders, *CORNEAL cross-linking, *INTRAOCULAR lenses, *VISUAL acuity, *REFRACTIVE errors
Abstract

Keratoconus is an ectatic corneal disorder that causes severe vision loss. Surgical options allow us to correct, partially or totally, the induced refractive error. Intracorneal ring segments (ICRS) implantation represents a minimally invasive surgical option that improves visual acuity, with a high success rate and a low overall complication rate. Corneal allogenic ICRS consists of ring segments derived from allogenic eye bank-processed donor corneas. Selective topography-guided transepithelial photorefractive or phototherapeutic keratectomy combined with CXL is another way in selected cases to improve spectacles corrected distance visual acuity. The microphotoablative remodeling of the central corneal profile is generally planned by optimizing the optical zones and minimizing tissue consumption. Phakic intraocular lens (PIOL) implant is considered in patients with stable disease and acceptable anatomical requirements. The two types of pIOLs, depending on their implantation inside the eye, are anterior chamber-pIOLs, which fixate to the anterior surface of the iris by using a polymethomethacrolate claw at the two haptics, and posterior chamber-pIOLs. In patients with both cataracts and keratoconus, the correct IOL power is difficult to obtain due to the irregular corneal shape and K values. Toric IOL is recommended, but carefully judging the topography and the possible need of subsequent keratoplasties. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Direct Versus Indirect Corneal Neurotization for the Treatment of Neurotrophic Keratopathy

Author

Fogagnolo, Paolo, primary, Giannaccare, Giuseppe, additional, Bolognesi, Federico, additional, Digiuni, Maurizio, additional, Tranchina, Laura, additional, Rossetti, Luca, additional, Dipinto, Angelica, additional, Allevi, Fabiana, additional, Lozza, Alessandro, additional, Rabbiosi, Dimitri, additional, Mariani, Silvia, additional, Pellegrini, Marco, additional, Cazzola, Federica E., additional, Bagaglia, Simone, additional, Mazzotta, Cosimo, additional, Gabriele, Guido, additional, Gennaro, Paolo, additional, Badiali, Giovanni, additional, Marchetti, Claudio, additional, Campos, Emilio C., additional, and Biglioli, Federico, additional

Published
2020
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17. Corneal Collagen Cross-Linking With Riboflavin and Ultraviolet A Light for Pediatric Keratoconus: Ten-Year Results

Author

Mazzotta, Cosimo, Traversi, Claudio, Baiocchi, Stefano, Bagaglia, Simone, Caporossi, Orsola, Villano, Antonio, Caporossi, Aldo, Caporossi, Aldo (ORCID:0000-0002-8680-3773), Mazzotta, Cosimo, Traversi, Claudio, Baiocchi, Stefano, Bagaglia, Simone, Caporossi, Orsola, Villano, Antonio, Caporossi, Aldo, and Caporossi, Aldo (ORCID:0000-0002-8680-3773)

Abstract

PURPOSE: To assess the 10-year follow-up efficacy and safety of riboflavin ultraviolet A-induced cross-linking (CXL) in a population of pediatric patients aged 18 years and younger with progressive keratoconus (KC).METHODS: The prospective longitudinal cohort study included 62 eyes of 47 keratoconic patients undergoing epithelium-off CXL who completed 10-year follow-up. The surgical procedure was performed in all patients according to the Siena (Dresden modified) protocol. Evaluation included uncorrected distance visual acuity, corrected distance visual acuity, Scheimpflug corneal tomography, and optical coherence tomography demarcation line measurement. Follow-up measurements taken up to 10 years after treatment were compared with baseline values, and statistical analysis was performed using a 2-tailed paired sample Student t test.RESULTS: Uncorrected distance visual acuity and corrected distance visual acuity improved from 0.45 to 0.23 logarithm of the minimum angle resolution (P = 0.0001) and from 0.14 to 0.1 logarithm of the minimum angle resolution (P = 0.019). KC stability was recorded after 10 years of follow-up in nearly 80% of the patients. The overall 10-year follow-up progression rate was 24% including 13 eyes of 9 patients with Kmax progression over 1 diopter and 2 eyes of 2 patients who underwent corneal grafting.CONCLUSIONS: The study demonstrates the ability of CXL to slow down KC progression in pediatric patients, improving functional performance. Long-term stability may be correlated with CXL-induced delay in corneal collagen turnover and with spontaneous age-related KC stabilization. A 24% regression rate could be contemplated in the patients who were aged 15 years and younger at the time of inclusion in the treatment protocol.

Published
2018

20. Erratum: Blindness and glaucoma: A multicenter data review from 7 academic eye clinics (PLoS ONE (2015) 10:8 (e0136632) DOI: 10.1371/journal.pone.0136632)

Author

Rossetti, Luca, Digiuni, Maurizio, Montesano, Giovanni, Centofanti, Marco, Fea, Antonio M., Iester, Michele, Frezzotti, Paolo, Figus, Michele, Ferreras, Antonio, Oddone, Francesco, Tanga, Lucia, Rolle, Teresa, Battaglino, Valentina, Posarelli, Chiara, Motolese, Ilaria, Mittica, Pietro, Bagaglia, SIMONE ALEX, Menicacci, Cristina, De Cilla, Stefano, Autelitano, Alessandro, and Fogagnolo, Paolo

Subjects
Genetics and Molecular Biology (all), Agricultural and Biological Sciences (all), Medicine (all), Biochemistry, Genetics and Molecular Biology (all), Biochemistry
Published
2016

21. Blindness and glaucoma: a multicenter data review from 7 academic eye clinic

Author

Rossetti, Luca, Digiuni, Maurizio, Giovanni, Montesano, Centofanti, Marco, Fea, Antonio M., Iester, Michele, Frezzotti, Paolo, Figus, Michele, Ferreras, Antonio, Oddone, Francesco, Tanga, Lucia, Rolle, Teresa, Battaglino, Valentina, Posarelli, Chiara, Motolese, Ilaria, Mittica, Pietro, Bagaglia, Simone Alex, Menicacci, Cristina, Cilla, Stefano De, Autelitano, Alessandro, and Fogagnolo, Paolo

Published
2015

22. Correction: Blindness and Glaucoma: A Multicenter Data Review from 7 Academic Eye Clinics

Author

Rossetti, Luca, primary, Digiuni, Maurizio, additional, Montesano, Giovanni, additional, Centofanti, Marco, additional, Fea, Antonio M., additional, Iester, Michele, additional, Frezzotti, Paolo, additional, Figus, Michele, additional, Ferreras, Antonio, additional, Oddone, Francesco, additional, Tanga, Lucia, additional, Rolle, Teresa, additional, Battaglino, Valentina, additional, Posarelli, Chiara, additional, Motolese, Ilaria, additional, Mittica, Pietro, additional, Bagaglia, Simone Alex, additional, Menicacci, Cristina, additional, De Cilla’, Stefano, additional, Autelitano, Alessandro, additional, and Fogagnolo, Paolo, additional

Published
2016
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24. Blindness and Glaucoma: A Multicenter Data Review from 7 Academic Eye Clinics

Author

Rossetti, Luca, primary, Digiuni, Maurizio, additional, Giovanni, Montesano, additional, Centofanti, Marco, additional, Fea, Antonio M., additional, Iester, Michele, additional, Frezzotti, Paolo, additional, Figus, Michele, additional, Ferreras, Antonio, additional, Oddone, Francesco, additional, Tanga, Lucia, additional, Rolle, Teresa, additional, Battaglino, Valentina, additional, Posarelli, Chiara, additional, Motolese, Ilaria, additional, Mittica, Pietro, additional, Bagaglia, Simone Alex, additional, Menicacci, Cristina, additional, De Cilla’, Stefano, additional, Autelitano, Alessandro, additional, and Fogagnolo, Paolo, additional

Published
2015
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29. Direct Versus Indirect Corneal Neurotization for the Treatment of Neurotrophic Keratopahty: a Multicenter Prospective Comparative Study

Author

Fogagnolo, P., Giannaccare, G., Bolognesi, F., Digiuni, M., Tranchina, L., Rossetti, L., Dipinto, A., Allevi, F., Lozza, A., Rabbiosi, D., Mariani, S., Pellegrini, M., Cazzola, F. E., Bagaglia, S., Mazzotta, C., Gabriele, G., Gennaro, P., Badiali, G., Marchetti, C., Campos, E. C., Biglioli, F., Fogagnolo, Paolo, Giannaccare, Giuseppe, Bolognesi, Federico, Digiuni, Maurizio, Tranchina, Laura, Rossetti, Luca, Dipinto, Angelica, Allevi, Fabiana, Lozza, Alessandro, Rabbiosi, Dimitri, Mariani, Silvia, Pellegrini, Marco, Cazzola, Federica E, Bagaglia, Simone, Mazzotta, Cosimo, Gabriele, Guido, Gennaro, Paolo, Badiali, Giovanni, Marchetti, Claudio, Campos, Emilio C, and Biglioli, Federico

Subjects
Adult, Male, corneal neurotization, neurotrophic keratopathy, maxillofacial surgery, ophthalmic surgery, Ophthalmic Nerve, maxillofacial surgery, ophthalmic surgery, Corneal Diseases, NO, Cornea, Young Adult, neurotrophic keratopathy, 80 and over, Humans, Prospective Studies, Nerve Transfer, Aged, Aged, 80 and over, corneal neurotization, ophthalmic surgery, maxillofacial surgery, neurotrophic keratopathy, Microscopy, Microscopy, Confocal, Female, Middle Aged, Treatment Outcome, Nerve Regeneration, Confocal, corneal neurotization
Abstract

PURPOSE: To analyze the comparative safety and efficacy of two techniques of corneal neurotization (CN) (direct corneal neurotization [DCN] vs indirect corneal neurotization [ICN] for the treatment of neurotrophic keratopathy (NK).DESIGN: Multicenter Interventional Prospective Comparative Case Series.METHODS: Setting: ASST Santi Paolo e Carlo University Hospital, Milan; S.Orsola-Malpighi University Hospital, Bologna; Santa Maria alle Scotte University Hospital, Siena.STUDY POPULATION: Consecutive patients with NK undergoing CN between November 2014 and October 2019; Intervention Procedures: DCN was performed by transferring contralateral supraorbital and supratrochlear nerves; ICN was performed using sural nerve graft.MAIN OUTCOME MEASURES: NK healing; corneal sensitivity; corneal nerve fiber length (CNFL) measured by in vivo confocal microscopy (IVCM); complication rate.RESULTS: 26 eyes of 25 patients were included: 16 were treated with DCN and 10 with ICN. After surgery, NK healed in all patients after a mean period of 3.9 months without differences between DCN and ICN. Mean corneal sensitivity improved significantly 1 year after surgery (from 3.07 to 22.11 mm; p

Published
2020

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