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Simple Summary: This study aimed to enhance the accuracy of detecting laryngeal carcinoma using a modified AI model based on U-Net. The model was designed to automatically identify lesions in endoscopic images. Researchers addressed issues such as mode collapse and gradient explosion to ensure stable performance, achieving 99% accuracy in detecting malignancies. The study found that malignant tumors were detected more reliably than benign ones. This technology could help reduce human error in diagnoses, allowing for earlier detection and treatment. Furthermore, it has the potential to be applied in other medical fields, benefiting overall healthcare. This study modifies the U-Net architecture for pixel-based segmentation to automatically classify lesions in laryngeal endoscopic images. The advanced U-Net incorporates five-level encoders and decoders, with an autoencoder layer to derive latent vectors representing the image characteristics. To enhance performance, a WGAN was implemented to address common issues such as mode collapse and gradient explosion found in traditional GANs. The dataset consisted of 8171 images labeled with polygons in seven colors. Evaluation metrics, including the F1 score and intersection over union, revealed that benign tumors were detected with lower accuracy compared to other lesions, while cancers achieved notably high accuracy. The model demonstrated an overall accuracy rate of 99%. This enhanced U-Net model shows strong potential in improving cancer detection, reducing diagnostic errors, and enhancing early diagnosis in medical applications. [ABSTRACT FROM AUTHOR]