Search

Your search keyword '"Baek, Jae-Woo"' showing total 30 results
Start Over Author "Baek, Jae-Woo"
30 results on '"Baek, Jae-Woo"'

30. Photodynamic therapy with methyl-aminolaevulinic acid for mycosis fungoides.

Author

Kim ST, Kang DY, Kang JS, Baek JW, Jeon YS, and Suh KS

Subjects
Adult, Aged, Aminolevulinic Acid administration & dosage, Aminolevulinic Acid therapeutic use, Female, Humans, Male, Middle Aged, Mycosis Fungoides pathology, Occlusive Dressings, Photosensitizing Agents administration & dosage, Republic of Korea, Skin Neoplasms pathology, Aminolevulinic Acid analogs & derivatives, Mycosis Fungoides drug therapy, Photochemotherapy, Photosensitizing Agents therapeutic use, Skin Neoplasms drug therapy
Abstract

Mycosis fungoides is the most common type of cutaneous T-cell lymphoma. There are a wide range of treatments for early-stage and advanced-stage mycosis fungoides. Photodynamic therapy (PDT) has emerged as a new treatment modality due to its safety and efficacy. The aim of this study was to investigate the safety and efficacy of PDT with methyl-aminolaevulinic acid (MAL) for the treatment of mycosis fungoides. Ten patients with mycosis fungoides were enrolled in this study. A 16.8% MAL cream was applied under occlusive dressing for 3 h. The lesion was irradiated at 37.5 J/cm2 with red light. The patients underwent two sessions of PDT at one-week intervals. Follow-up biopsy was performed 3 months after the last treatment. In case of partial response, treatment was repeated once a week until complete response. Seven patients had a good therapeutic response. Complete and partial responses were seen in 5 and 2 patients, respectively. During the follow-up period (8-31 months), 6 of the 7 patients remained in stable remission. The treatment was well-tolerated overall, and no patients discontinued the PDT due to pain. In conclusion, PDT with MAL is a fast, effective and well-tolerated treatment for unilesional mycosis fungoides.

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results