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9 results on '"Bachetti G"'

2. HLA TYPING: A MOLECULAR APPROACH : 056

Author

Nardi, G., Bachetti, G., Canzian, A., Coccia, C., Demasi, O., Striani, P., Massi, L., Santini, N., Cicconi, G., Gagliardi, G., Grazioli, M., and Mazzocchi, G.

Published
1997

3. Chronic Idiopathic Thrombocytopenic Purpura (ITP) 51-Cr-Platelet Kinetics and Splenectomy in 197 Patients

Author

G. Isacchi, Sante Tura, Maria Rosa Motta, Attilio Guarini, Franco Mandelli, Bachetti G, and Luigi Gugliotta

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Internal medicine, Splenectomy, Chronic idiopathic thrombocytopenic purpura, medicine, Platelet, business, Gastroenterology
Abstract

51cr-Platelet Kinetics was studied in 197 patients with Chronic ITP of which 111 were submitted to splenectomy after the study.Platelet half life-span was always decreased (< 24 hours).Platelet, sequestration was splenic, spleno-hepatic, hepato-splenic, hepatic and diffuse in 56%, 18%, 1%, 6% and 19% of patients respectively. Platelet life-span and sequestration were not correlated with sex, age, platelet number, duration and severity of disease.101 patients with splenic and spleno-hepatic platelet sequestration underwent splenectomy. Their follow-up is 1-5 years. Complete (steady platelet level > 150,000μl) or partial (platelet level in between 80,000 and 15,000/μ1) remission was obtained in 83% and 6% of them respectively. In 10 patients with non-splenic platelet segue-stration complete and partial remission’after splenectomy were observed in 5 and 1 gases respectively. 51Cr-Platelet Kinetics is a reliable and useful predictor of the therapeutic value of splenectomy. However splenectomy should be considered also in selected case with non splenic platelet sequestration.

Published
1979

5. Long-term survival in adult acute leukemia. A multicenter study of 56 patients

Author

Tura, S., Gobbi, M., Cavo, M., Bachetti, G., Mandelli, F., Sergio Amadori, Petti, M. C., Quattrin, N., Rosa, L., Storti, E., Rizzo, S. C., Bernasconi, C., Salvaneschi, L., Paolino, W., Infelise, V., Dini, E., Barbui, T., Bruzzese, L., Abbadessa, A., Martelli, M. F., and Rambotti, P.

Subjects
Adult, Male, Leukemia, Adolescent, Age Factors, Middle Aged, Prognosis, Leukemia, Lymphoid, Leukemia, Myeloid, Acute, Humans, Drug Therapy, Combination, Female, Child, Aged
Published
1982

8. [Thrombocythemias (author's transl)].

Author

Tura S, Alimena G, Artusi T, Baccarani M, Bachetti G, Bernasconi C, Betti S, Biagini G, Boccaccio P, Canevari A, Chezzi C, Ciccone F, Grossi A, Guarini A, Gugliotta L, Isacchi G, Laschi R, Mannucci PM, Morfini M, Motta MR, Pareti FI, Ricci P, Rossi A, Rossi-Ferrini PL, Salvaneschi L, Salvidio E, Sessarego M, and Zaccaria A

Subjects
Humans, Thrombocythemia, Essential etiology, Thrombocythemia, Essential therapy, Thrombocytosis etiology, Thrombocytosis therapy, Thrombocythemia, Essential pathology, Thrombocytosis pathology
Published
1979

9. Chronic idiopathic thrombocytopenic purpura (ITP): site of platelet sequestration and results of splenectomy. A study of 197 patients.

Author

Gugliotta L, Isacchi G, Guarini A, Ciccone F, Motta MR, Lattarini C, Bachetti G, Mazzucconi MG, Baccarani M, Mandelli F, and Tura S

Subjects
Adolescent, Adult, Aged, Child, Child, Preschool, Chromium Radioisotopes, Chronic Disease, Female, Humans, Infant, Kinetics, Male, Middle Aged, Platelet Count, Purpura, Thrombocytopenic therapy, Blood Platelets physiology, Purpura, Thrombocytopenic blood, Splenectomy
Abstract

51Cr-platelet kinetics study was performed in 197 patients with chronic ITP after corticosteroid therapy had failed to induce a long lasting remission. The incidence of splenic, spleno-hepatic, hepatic and diffuse platelet sequestration site was 58%, 17%, 6% and 19%, respectively. Splenic and spleno-hepatic sequestration sites were more frequent in patients less than 30 years old and in patients with a platelet count lower than 50 x 10(9)/1. 111 patients were splenectomized shortly after the study. Normalization of the platelet count was obtained more frequently in patients with splenic and spleno-hepatic sequestration than in the others. Labelled platelet sequestration site was the best predictor of the outcome of splenectomy. Platelet kinetics is a non-invasive investigation that should be performed early after the diagnosis of chronic ITP in all patients eligible for splenectomy.

Published
1981
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