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7. Profilo auxologico, metabolico ed endocrino in pazienti epilettici in età evolutiva in terapia con acido valproico

Author

Santangelo, G, Vanadia, E, Camarda, I, Buffa, D, Manzoni, D, Vanadia, F, MAGGIO, Maria Cristina, PANZECA, Rossana, LIOTTA, Andrea, CORSELLO, Giovanni, Santangelo, G, Vanadia, E, Camarda, I, Buffa, D, Manzoni, D, Vanadia, F, Maggio, MC, Panzeca, R, Liotta, A, and Corsello, G

Subjects
epilessia, acido valproico, tiroide, pubertà, Settore MED/38 - Pediatria Generale E Specialistica
Published
2009

8. Incremento dei livelli di 17-idrossiprogesterone in pazienti con sclerosi multipla in età pediatrica

Author

Santangelo, G, Vanadia, E, Camarda, I, Buffa, D, Manzoni, D, Vanadia, F, MAGGIO, Maria Cristina, PANZECA, Rossana, LIOTTA, Andrea, CORSELLO, Giovanni, Santangelo, G, Vanadia, E, Camarda, I, Buffa, D, Manzoni, D, Vanadia, F, Maggio, MC, Panzeca, R, Liotta, A, and Corsello, G

Subjects
Settore MED/38 - Pediatria Generale E Specialistica, sclerosi multipla, 17-idrossiprogesterone
Published
2009

10. Rottura di rene trapiantato.Analisi di due casi

Author

LO MONTE, Attilio Ignazio, GIOVIALE, Maria Concetta, ZUMBINO, Carmelo, SCIO, Antonio, DAMIANO, Giuseppe, BUSCEMI, Giuseppe, ROMANO, Maurizio, MAIONE C, BUFFA D, FALCONE G., LO MONTE AI, GIOVIALE MC, MAIONE C, ZUMBINO C, BUFFA D, SCIO A, DAMIANO G, BUSCEMI G, ROMANO M, and FALCONE G

Published
2005

13. La colecistectomia laparoscopica nel paziente uremico

Author

ROMANO, Giorgio, COCCHIARA G, CAJOZZO, Massimo, CALDERONE, Fiorella, BUFFA D, LO MONTE, Attilio Ignazio, BUSCEMI, Giuseppe, DIANA G, ROMANO, Maurizio, ROMANO G, COCCHIARA G, CAJOZZO M, CALDERONE F, BUFFA D, LO MONTE AI, BUSCEMI G, DIANA G, and Romano, M.

Published
2004

14. A transcranial magnetic stimulation study evaluating methylprednisolone treatment in multiple sclerosis

Author

FIERRO, Brigida, SALEMI, Giuseppe, BRIGHINA, Filippo, LA BUA, Vincenzo, SAVETTIERI, Giovanni, Buffa, D., Conte, S., Piazza, A., Fierro, B., Salemi, G., Brighina, F., Buffa, D., Conte, S., La Bua, V., Piazza, A., and Savettieri, G.

Subjects
Neuroscience (all), High dose methylprednisolone, Multiple sclerosi, Settore MED/26 - Neurologia, Neurology (clinical), Randomized trial, Transcranial magnetic stimulation
Abstract

Objective - To investigate the efficacy of two different high doses of intravenous methylprednisolone (IVMP) during Multiple Sclerosis (MS) relapses. Background - Transcranial Magnetic Stimulation (TMS) is the most sensitive neurophysiological ascertainment to quantify motor disability, to follow the recovery from an MS relapse, and to detect the response to treatment. Design and method - Twenty-four clinically definite relapsing - remitting MS patients presenting a relapse were randomly assigned to a treatment for 5 days with IVMP 1 or 2 g/day. The response to treatment of each patient was evaluated through Expanded Disability Status Scale (EDSS), Medical Research Council (MRC) score, and TMS by means of motor evoked potential (MEP) parameters. Results - Motor threshold (MT), central motor conduction time (CMCT) and MRC showed a higher improvement with the highest dose of IVMP. Silent period and EDSS improved with both treatments. Conclusion - The dose of 2 g/day of IVMP is more effective in MS relapse.

Published
2002

15. Is season of birth associated with multiple sclerosis?

Author

Salemi, G, Ragonese, P, Aridon, P, Reggio, A, Nicoletti, Alessandra, Buffa, D, Conte, S, Savettieri, G., Salemi, G., Ragonese, P., Aridon, P., Reggio, A., Nicoletti, A., Buffa, D., Conte, S., and Savettieri, G.

Subjects
Neuroscience (all), Multiple sclerosi, Settore MED/26 - Neurologia, Risk factor, Seasonality, Neurology (clinical), Month of birth
Abstract

Objective - To compare the monthly distribution of multiple sclerosis (MS) patients' births with that of the Sicilian population. Background - Studies on the association between season of birth and risk of MS are scanty and controversial. Design and methods - Archives of the Institute of Neuropsychiatry of the Universities of Palermo and Catania were searched up to 1995 for definite MS patients (McDonald and Halliday criteria). The monthly distribution of MS patients' births (N = 965) was compared with that of the Sicilian population (N = 5,608,307). Results - The distribution of births among MS patients compared with the general population was not different when tested by the χ2 statistic (P > 0.25). The Hewitt's non- parametric test for seasonality showed an excess of births between June and November among MS patients (P = 0.004). Conclusion - A different pattern of MS patients' births is observed in Sicily and in Northern countries.

Published
2000

16. Contralateral neglect induced by right posterior parietal rTMS in healthy subjects

Author

Fierro, B., Filippo BRIGHINA, Oliveri, M., Piazza, A., La Bua, V., Buffa, D., and Bisiach, E.

Subjects
Adult, Magnetics, Parietal Lobe, Space Perception, General Neuroscience, Agnosia, Humans, Middle Aged, Electric Stimulation, Functional Laterality, Photic Stimulation, Psychomotor Performance, Aged
Abstract

We applied repetitive transcranial magnetic stimulation (rTMS) in order to induce interference on visuo-spatial perception in 11 healthy subjects. Subjects performed a visuo-spatial task requiring judgements about the symmetry of prebisected lines. Visual stimuli consisted of symmetrically or asymmetrically transected lines, tachystoscopically presented for 50 ms on a computer-monitor. Performance was examined in basal condition and during rTMS trains of 10 stimuli at 25 Hz, delivered through a focal coil over right or left posterior parietal cortex (P5 and P6 sites) and triggered synchronously with visual stimulus. Randomly intermixed sham rTMS trains were employed to control for non-specific effects. Right parietal rTMS induced a significant rightward bias in symmetry judgements as compared with basal and sham rTMS conditions. No differences emerged between other conditions.

Published
2000
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20. Coffee consumption and Parkinson's disease

Author

Ragonese, P., Morgante, Letterio, Salemi, G., Epifanio, A., Buffa, D., Aridon, P., Cammarata, E., Maimone, M., Scoppa, F., and Savettieri, G.

Published
2000

21. The Legacy

Author

Buffa, D. W. and Buffa, D. W.

Subjects
Medical students--Fiction, African American students--Fiction, Legislators--Crimes against--Fiction, Trials (Murder)--Fiction
Abstract

A young black student is on trial for the murder of a hot-shot California senator. The student claims he is innocent, but all the evidence indicates otherwise. Joseph Antonelli leaves his Oregon law practice to put up a case for the defence. He soon discovers a world of deceit, betrayal and naked ambition.

Published
2008

24. Migraine and Cranial Autonomic Symptoms in Children and Adolescents: A Clinical Study.

Author

Raieli, V., Giordano, G., Spitaleri, C., Consolo, F., Buffa, D., Santangelo, G., Savettieri, G., Vanadia, F., and D’Amelio, M.

Subjects
MIGRAINE, HEADACHE, TEENAGERS, NEUROLOGY, PEDIATRIC neurology
Abstract

The frequency of cranial autonomic symptoms in children affected by primary headaches is uncertain. The aim of our study was to estimate the frequency of symptoms in pediatric headaches and correlate it with main migraine characteristics. A questionnaire investigating the presence of cranial autonomic symptoms was administered to all children with primary headache for 2 years. A total of 230 children with primary headache (105 males, 125 females) were included. Two hundred two children were affected by migraine and 28 (12.2%) by other primary headaches. Cranial autonomic symptoms were significantly complained by migraineurs (55% vs 17.8%) (P < .001) and by children with higher frequency of migraine attacks (odds ratio = 2.6, confidence interval = 1.4-4.7, P = .001). Our findings show that cranial autonomic symptoms are rather common during pediatric migraine attacks. The association between cranial autonomic symptoms and higher frequency of attacks might suggest the role of the trigeminal-autonomic reflex in migraine pathophysiology. [ABSTRACT FROM PUBLISHER]

Published
2015
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28. Trial by Fire

Author

Buffa, D W and Buffa, D W

Abstract

Murder can be a very public affair, as famed defence attorney Joseph Antonelli discovers, in this moody and thrilling novel of love, loyalty, and revenge in the Edgar Award-nominated series.Joseph Antonelli has never lost a case he should have won... until now. Julian Sinclair is a brilliant young man on the path to greatness, but he is also a man with powerful emotions he tries to keep in check. When a beautiful woman, a married district attorney, is murdered, Sinclair is accused of killing her in a fit of jealous rage. He claims that she was the victim of her sadistic husband, but the media, especially television, wildly condemn Sinclair, and whip the public into a frenzy.Antonelli does not doubt for a minute that the idealistic Sinclair is innocent. But the victim's widowed husband, a man of wealth and privilege and a master of manipulation, is determined to destroy both this remarkable defendant and the shrewd Antonelli. This is one case Antonelli can't win by playing fair. He has to bait the real killer out of hiding, force him to confess his crimes, even if it means putting himself in danger. Trial by Fire is about the power of television and how an innocent man can be convicted when the media insist he is guilty.From the author of the acclaimed Joseph Antonelli novels, Trial by Fire is D W Buffa's seventh book in the series.

Published
2005

34. The Judgment

Author

Buffa, D. W. and Buffa, D. W.

Subjects
Judges--Fiction, Trials (Murder)--Fiction
Abstract

When Judge Calvin Jeffries becomes the first sitting judge to be murdered while serving in office, charismatic criminal defense attorney Joseph Antonelli finds himself smack in the middle of a riveting case. As he works through the intricacies of a homicide audacious enough to strike at the heart of justice, the ensuing investigation and trial reveal a deadly trail of evil, shattered lives, and revenge. While challenging traditional notions of crime and punishment, the novel also calls into question the very principles of our judicial system and marks the breakthrough of a master storyteller. D.W. Buffas The Defense (Henry Holt, 1997) received great praise and grossed more than 40,000 hardcover copies. The Prosecution (Henry Holt, 1999) was also lauded by critics and garnered equally impressive sales.

Published
2001

35. Murein synthesis and beta-lactam antibiotic susceptibility during rod-to-sphere transition in a pbpA(Ts) mutant of Escherichia coli

Author

Botta, G A and Buffa, D

Abstract

The conditional morphology mutant of Escherichia coli SP45 grows as a rod at 30 degrees C and assumes a spherical shape after 90 min of incubation at 42 degrees C. The rod-to-sphere morphological transition has been found to be associated with the disappearance of penicillin-binding protein 2 (PBP-2), the progressive reduction (as much as 50%) of murein synthesis, as measured both in intact cells and ether-permeabilized bacteria, and alterations in the structure of the cell envelope, including detachment of the outer membrane from the underlying structures. The detachment was initially localized at the poles of the cells and then spread over the entire surface. Shape transition was also linked to increased susceptibility to beta-lactam antibiotics which preferentially bound to PBP-1A (cephalothin, cephaloridine) or to PBP-3 (furazlocillin, piperacillin). Treatment with beta-lactams possessing a high affinity for PBP-1A, although inducing a low degree of peptidoglycan synthesis inhibition (5 to 10%), was associated with a marked loss of cell viability and massive lysis. On the other hand, the simultaneous absence of PBP-2 and inhibition of PBP-3 causes a significant reduction of peptidoglycan synthesis, yet only slightly affected cell viability. Whereas PBP-1A inhibition during shape transition had no effect on morphology, addition of antibiotics binding to PBP-3 30 min after the temperature shift-up caused formation of elongated cells with a centrally located bulge, not observed in similarly treated cells grown at 30 degrees C. Inhibition of PBP-3 in round cells 90 min after temperature shift caused formation of giant cells, indicating complete loss of elongation ability. The different effects of the simultaneous inhibition of two PBPs, combining mutational loss with specific binding in vivo of another PBP by beta-lactams, provide new insight into the role of these proteins and the killing mechanisms of this class of antibiotics.

Published
1981
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36. Blue nevus of the uterine cervix

Author

Donofrio, V., Luigi Maria TERRACCIANO, Boscaino, A., Rosa, G., Buffa, D., Donofrio, V, Terracciano, Lm, Boscaino, A, DE ROSA, Gaetano, and Buffa, D.

Subjects
Neoplasms, Multiple Primary, Microscopy, Electron, Nevus, Pigmented, Ovarian Cysts, Leiomyoma, Uterine Neoplasms, Humans, Melanocytes, Uterine Cervical Neoplasms, Female, Dendritic Cells, Middle Aged, Biomarkers
Abstract

A case of blue naevus of the endocervix is reported with immunohistochemical and ultrastructural findings. The dendritic melanin-containing cells are analogous to the blue naevi cells of the skin. Electron microscopy showed melanosomes in dendritic cells but no cells with melanin-producing Schwann cells features were observed. Histogenetic hypotheses are discussed.

37. A simple method to treat post-kydney transplantation lymphocele

Author

Giuseppe Damiano, Lombardo, C., Palumbo, V. D., Buffa, D., Maione, C., Gioviale, M. C., Cacciabaudo, F., Spinelli, G., Calvagna, C., Lo Monte, A. I., Damiano, G, Lombardo, C, Palumbo, VD, Buffa, D, Maione, C, Gioviale, MC, Cacciabaudo, F, Spinelli, G, Calvagna, C, and Lo Monte, AI

Subjects
Adult, Male, Settore MED/18 - Chirurgia Generale, Instillation, Drug, Lymphocele, Sclerotherapy, Humans, Middle Aged, US-guided percutaneous treatment, Kidney Transplantation, Povidone-Iodine, Sclerosing Solutions, Ultrasonography
Abstract

OBJECTIVE: To describe our experience with ultrasonic-guided instillation of povidone-iodine to treat post-kidney transplantation lymphocele. Patients and methods. We studied the safety and efficacy of this procedure for treatment of lymphocele in 6 male kidney transplanted recipients in which we assisted a progressive increase of creatinine and urinary proteins levels and color-Doppler ultrasonography demonstrated an increase (25,4%) of index of resistence (IR) Using eco-colorDoppler, the related-graft lymphocele location and the distance to the anterior abdominal wall were determined; then, a radiopaque double-lumen catheter was used to instillate 5% povidone-iodine 10 ml. Results. Percutaneous drainage achieved a resolution rate of 100%. Studying the rate of peripheral and internal vascularization of the kidney before and after treatment, eco-colorDoppler showed a significant decrease of the IR (24,6%). Conclusions. The US-guided povidone-iodine instillation for treatment of lymphocele following renal transplantation may be considered as first choice therapy in such disease.

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